Chancellor |
 | Jeffrey S. Vitter, PhD Chancellor | Biography |
Vice Chancellor |
 | LouAnn Woodward, MD Vice Chancellor for Health Affairs and Dean of the School of Medicine | Biography |
Executive Cabinet |
 | Ralph H. Didlake, MD, MA Associate Vice Chancellor for Academic Affairs and Chief Academic Officer | Biography |
 | Charles S. O'Mara, MD Associate Vice Chancellor for Clinical Affairs | Biography |
 | Richard L. Summers, MD Associate Vice Chancellor for Research | Biography |
 | Claude Brunson, MD Senior Advisor to the Vice Chancellor, External Affairs | Biography |
 | Kevin Cook, MSBA Health System Chief Executive Officer | Biography |
 | Sam E. Smith Jr., CPA Interim Chief Financial Officer Chief Accounting Officer; Comptroller |
 | Thomas H. Fortner, MBA Chief Public Affairs and Communications Officer |
 | Guy Giesecke, MBA, MHA, DHA Chief Executive Officer, Children's of Mississippi | Biography |
 | Paula M. Henderson, MBA Chief Human Resources Officer |
 | Loretta Jackson-Williams, MD Vice Dean for Medical Education, School of Medicine | Biography |
 | Brian Rutledge, PhD Chief of Staff, Office of the Vice Chancellor | Biography |
 | Juanyce Taylor, PhD Chief Diversity and Inclusion Officer | Biography |
 | Paul Veregge, MD Chief Information Officer and Chief Medical Information Officer |
 | Stephanie Jones, JD Interim General Counsel and Chief Legal Officer |
 | Jonathan Wilson, RN, PhD Chief Administrative Officer | Biography |
Academic Officers |
 | Jessica Bailey, PhD Dean of the School of Health Related Professions |
 | Bettina M. Beech, DrPH Dean of the School of Population Health |
 | Joey Granger, PhD Dean of the School of Graduate Studies in the Health Sciences |
 | Kim Hoover, RN, PhD Dean of the School of Nursing |
 | David Felton, DMD Dean of the School of Dentistry |
 | Leigh Ann Ross, PhD Associate Dean for Clinical Affairs, School of Pharmacy |
Emeriti |
Edrie J. George, MSN, EdD | Dean Emeritus of the School of Nursing |
James E. Keeton, MD | Vice Chancellor Emeritus for Health Affairs Dean Emeritus of the School of Medicine |
J. Perry McGinnis, DDS | Dean Emeritus of the School of Dentistry |