| Vice Chancellor |
 | LouAnn Woodward, MD
Vice Chancellor for Health Affairs and Dean of the School of Medicine | Biography |
| Executive Cabinet |
 | Ralph H. Didlake, MD
Associate Vice Chancellor for Academic Affairs and Chief Academic Officer | Biography |
 | Alan E. Jones, MD
Associate Vice Chancellor for Clinical Affairs | Biography |
 | Richard L. Summers, MD
Associate Vice Chancellor for Research | Biography |
 | Molly Brasfield, MS
Chief Human Resources Officer |
 | Britt H. Crewse, MBA, MHS, CPA
Chief Executive Officer, Adult Hospitals |
 | Guy B. Giesecke, FACHE
Chief Executive Officer, Children’s of Mississippi |
 | Dodie T. McElmurray, RN, BSN, MSN/MBA, FACHE
Chief Executive Officer, Community Hospitals |
 | Marc Rolph
Executive Director, Office of Communications and Marketing |
 | Brian Rutledge, PhD
Chief of Staff, Office of the Vice Chancellor | Biography |
 | Juanyce Taylor, PhD
Chief Diversity and Inclusion Officer | Biography |
 | William Smith III, JD
General Counsel and Chief Legal Officer |
 | Nelson C. Weichold, MHA
Chief Financial Officer |
 | Jonathan Wilson, PhD
Chief Administrative Officer | Biography |
| Academic Officers |
 | Jessica Bailey, PhD
Dean of the School of Health Related Professions |
 | Sreenivas Koka, DDS, MS, PhD, MBA
Dean of the School of Dentistry |
 | Natalie W. Gaughf, PhD
Interim Dean of the School of Population Health |
 | Joey Granger, PhD
Dean of the School of Graduate Studies in the Health Sciences |
 | Loretta Jackson-Williams, MD
Vice Dean for Medical Education, School of Medicine | Biography |
 | Leigh Ann Ross, PharmD
Associate Dean for Clinical Affairs, School of Pharmacy |
 | Julie Sanford, DNS
Dean of the School of Nursing |
| Emeriti |
| Edrie J. George, MSN, EdD | Dean Emeritus of the School of Nursing |
| Buford Gilbert, DMD | Dean Emeritus of the School of Dentistry |
| Willie Hill, DDS, MS | Dean Emeritus of the School of Dentistry |
| Daniel W. Jones, MD | Vice Chancellor Emeritus for
Health Affairs and Dean Emeritus of the School of Medicine |
| James E. Keeton, MD | Vice Chancellor Emeritus for Health Affairs
Dean Emeritus of the School of Medicine |
| J. Perry McGinnis, DDS | Dean Emeritus of the School of Dentistry |
| Gary Reeves, DMD | Dean Emeritus of the School of Dentistry |