CVs

VI BICH NGUYEN

My primary research interest is vascular malformations, which focused on neurovascular interaction and epigenetic role in pathogenesis.

University of South Carolina, School of Medicine
Columbia, South Carolina
Ph.D. in Biomedical Science
August 2021 – present

University of California, Irvine
Irvine, California
Bachelor of Science, Biological Sciences
June 2018

Golden West College
Huntington Beach, California
Associate of Art, Biology
May 2016

Lab Technician
Columbia, South Carolina
University of South Carolina, School of Medicine
November 2018 – July 2021

Principal Investigator: Wenbin Tan
Organize and manage equipment and supplies
Assist with ordering lab supplies
Conduct experiments for the projects
- Project 1: investigate neurovascular interaction in vascular malformation pathogenesis, which focused on the brain-derived neurotrophic factor (BDNF). Study the relationship between BDNF and epigenetic in vascular malformation.
- Project 2: Investigate the role of lipid in Covid-19 viral entry and spike protein functions in cellular metabolism. Study the LDL and HDL role in a spike pseudo- virus entry in macrophage cell, RAW cell, and endothelial cell. Study function of spike protein in the Nrf2 pathway in lipid toxicity and oxidative stress
Train and assist undergraduate students with experiments
Maintain and breed mice colonies

Research Assistant
Irvine, California
University of California, Irvine
February 2017 – June 2018

Principal Investigator: Wenbin Tan
Assisted and conducted experiments: Western Blot, Immunohistochemistry, Paraffin Sectioning

Teaching Assistant – Cell and Molecular Biology Lab
Huntington Beach, California
Golden West College
August 2014 – December 2014

Nguyen V, Hochman M, Mihm MC Jr, Nelson JS, Tan The Pathogenesis of Port Wine Stain and Sturge Weber Syndrome: Complex Interactions between Genetic Alterations and Aberrant MAPK and PI3K Activation. Int J Mol Sci. 2019 May 7;20(9):2243. doi: 10.3390/ijms20092243. PMID: 31067686; PMCID: PMC6539103.
Cao X, Tian Y, NguyenV, Zhang Y, Gao C, Yin R, Carver W, Fan D, Albrecht H, Cui T, Tan W. Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice. FASEB J. 2021 Sep;35(9):e21801. doi: 10.1096/fj.202002742RR. PMID: 34365657; PMCID: PMC8441663. (co-first authors)
Li G, Du L, Cao X, Wei X, Jiang Y, Lin Y, Nguyen V, Tan W, Wang Follow-up study on serum cholesterol profiles and potential sequelae in recovered COVID-19 patients. BMC Infect Dis. 2021 Mar 24;21(1):299. doi: 10.1186/s12879-021-05984-1. PMID: 33761881; PMCID: PMC7989719. (co-author)
Nguyen V, Zhang Y, Gao C, Cao X, Tian Y, Carver W, Kiaris H, Cui T, Tan W. The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Cells. 2022 Jun 14;11(12):1916. doi: 10.3390/cells11121916. PMID: 35741045; PMCID: PMC9221434.

The Regents’ Scholarship – University of California, Irvine | September 2016
Dean’s Honor List – University of California, Irvine | January 2017, June 2018
Academic Honor list – Golden West College | August 2013 – May 2016
Patrons Monarch Scholarship – Golden West College | May 2016
Aminoil, C.B. Hill and Dennis F. Roughton Memorial Science Scholarship - Golden West College | May 2016
ASGGWC Perpetual Scholarship - Golden West College | May 2015
CA Community College Endowment OSHER Scholarship - Golden West College | May 2015
Southern California (STEM) Scholarship – Golden West College | May 2014

Computer: Word, Excel, PowerPoint, ImageJ, Origin, RStudio
Lab equipment: centrifuge, thermal cycler, nanodrop, microtome, microscope (bright field, EVOS, confocal), Bio-rad Chemidoc, qPCR Bio-rad CFX
Language: English, Vietnamese

University of California – Irvine Alumni Association | June 2018 – present

Orange County Community Health Affiliation | March 2018 – present

Pre-Pharmacy Society – University of California, Irvine | September 2017 – June 2018

Alpha Gamma Sigma Golden West College Honor Society | February 2015 – May 2016

International Student Club – Golden West College | August 2012 – May 2016