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Reportable Cancer List DX 10/2023 or later
REPORTABLE CASES – MISSISSIPPI
For cases diagnosed 10/1/2023 and after
The following lists are intended to assist you, as the reporter, in identifying the reportable neoplasms for your facility. Any reportable neoplasms diagnosed on or after January 1, 1996 should be reported to the Mississippi Cancer Registry.
REPORTABLE NEOPLASMS- Malignant neoplasms (Behavior 2 and 3) (exclusions noted below)
- Benign and borderline neoplasms of the central nervous system (Cases diagnosed on or after January 1, 2004)
- Squamous intraepithelial neoplasia grade III of vulva [VIN], vagina [VAIN], and anus [AIN] beginning with 2001 cases.
- Carcinoid, NOS of the appendix is reportable and should be coded with a behavior of 3 (Cases diagnosed on or after January 1, 2015)
- Lobular neoplasia grade III (LN III)/lobular intraepithelial neoplasia grade III (LIN III) breast C500-C509 (January 1, 2016 and forward)
- Pancreatic intraepithelial neoplasia (PanIN III) (January 1, 2016 and forward)
- Penile intraepithelial neoplasia III (PeIN III) (January 1, 2016 and forward)
- GIST tumors, all histologies changed to behavior 3 in ICD-O-3.2 (Cases diagnosed January 1, 2021 and later).
- Thymoma, most behaviors changed to 3 in ICD-O-3.2 (January 1, 2021 and later).
- GIST, NOS with multiple tumor foci and/or metastatic to lymph nodes or distant sites (Prior to January 1, 2021)
- Early or evolving melanoma in situ, or any other early or evolving melanoma beginning January 1, 2021 and forward.
- Low-grade appendiceal mucinous neoplasm (LAMN) behavior changed to 2 effective January 1, 2022.
- High-grade appendiceal mucinous neoplasm (HAMN) behavior changed to 2 effective January 1, 2022.
These are just some highlighted reportable conditions. For all reportable histologies, refer to https://www.naaccr.org/icdo3/ for the lists of reportable conditions reportable as of January 1, 2024.
NON-REPORTABLE NEOPLASMS- Skin cancers (C44._) with histologies 8000-8005, 8010-8046, 8050-8084, 8090-8110
- CIS of the cervix and CIN III and SIN III
- PIN III (January 1, 2001 and later)
- Borderline cystadenomas (ICD-O-3 Histologies 8442, 8451, 8462, 8472, 8473), of the ovaries with behavior code “1” are not collected as of January 1, 2001
- Cyst, brain or CNS tumor that does not have an ICD-O-3 code as of January 1, 2004
- Colorectal tumors with the following morphologic description:
- Serrated dysplasia, high grade
- Adenomatous polyp, high grade dysplasia
- Tubular adenoma, high grade
- Villous adenoma, high grade
- Tubulovillous adenoma, high grade
- Microscopic thymoma or thymoma benign (8580/0), micronodular thymoma with lymphoid stroma (8580/1), and ectopic hamartomatous thymoma (8587/0)
These are just some highlighted non-reportable conditions. For all reportable/non-reportable histologies, refer to https://www.naaccr.org/icdo3/ for the lists of reportable/non-reportable conditions as of January 1, 2024.
AMBIGUOUS TERMINOLOGYAll diagnostic reports should be reviewed for reportability. If the terminology is ambiguous, use the following list to determine if the case should be reported.
Terms That Constitute a Diagnosis** | Terms That Do Not Constitute a Diagnosis |
Apparent(ly) | Cannot be ruled out |
Appears | Equivocal |
Comparable with | Possible |
Compatible with | Potentially malignant |
Consistent with | Questionable |
Favors | Rule out |
Malignant appearing | Suggests |
Most likely | Worrisome |
Presumed | |
Probable | |
Suspect(ed) | |
Suspicious (for) | |
Typical of | |
Tumor (beginning with 2004 diagnosis and only for C70.0-C72.9, C75.1-C75.3) | |
Neoplasm (beginning with 2004 diagnosis and only for C70.0-C72.9, C75.1-C75.3) |
** Do not substitute synonyms such as "supposed" for "presumed" or "equal" for "comparable." Do not substitute "likely" for "most likely." Use on the exact words on the list.
Exceptions:
- If a cytology is reported using any ambiguous term, do not interpret it as a diagnosis of cancer. Abstract the case only if a positive biopsy or a physician’s clinical impression of cancer supports the cytology findings.
- Genetic findings in the absence of pathologic or clinical evidence of reportable disease are indicative of risk only and do not constitute a diagnosis.
COMPREHENSIVE ICD-10-CM CASEFINDING CODE LIST FOR REPORTABLE TUMORS
ICD-10-CM Codes | Explanation of Codes |
C00._-C43._, C4A._, C45._- C48._, C49._ - C96._ | Malignant neoplasms (excluding category C44 and C49.A), stated or presumed to be primary (of specified site) and certain specified histologies 1 |
C44.00, C44.09 | Unspecified/other malignant neoplasm of skin of lip |
C44.10_, C44.19_ | Unspecified/other malignant neoplasm of skin of eyelid |
C44.13_ | Sebaceous cell carcinoma of the skin of eyelid (Effective 10/1/2018) |
C44.20_, C44.29_ | Unspecified/other malignant neoplasm skin of ear and external auricular canal |
C44.30_, C44.39_ | Unspecified/other malignant neoplasm of skin of other/unspecified parts of face |
C44.40, C44.49 | Unspecified/other malignant neoplasm of skin of scalp & neck |
C44.50_, C44.59_ | Unspecified/other malignant neoplasm of skin of trunk |
C44.60_, C44.69_ | Unspecified/other malignant neoplasm of skin of upper limb, incl. shoulder |
C44.70_, C44.79_ | Unspecified/other malignant neoplasm of skin of lower limb, including hip |
C44.80, C44.89 | Unspecified/other malignant neoplasm of skin of overlapping sites of skin |
C44.90, C44.99 | Unspecified/other malignant neoplasm of skin of unspecified sites of skin |
C49.A_ | Gastrointestinal Stromal Tumors Note: All GIST are reportable beginning 1/1/2021. |
D00._, D05._, D07._, D09._ | In-situ neoplasms (Note: Carcinoma in situ of the cervix (CIN III-8077/2), Prostatic Intraepithelial Carcinoma (PIN III-8148/2), and basal and squamous cell in situ lesions of of skin are not reportable). |
D18.02 | Hemangioma of intracranial structures and any site |
D32._ | Benign neoplasm of meninges (cerebral, spinal and unspecified) |
D33._ | Benign neoplasm of brain and other parts of central nervous system |
D35.2 - D35.4 | Benign neoplasm of pituitary gland, craniopharyngeal duct and pineal gland |
D42._, D43._ | Neoplasm of uncertain or unknown behavior of meninges, brain, CNS |
D44.3 – D44.5 | Neoplasm of uncertain or unknown behavior of pituitary gland, craniopharyngeal duct and pineal gland |
D45 | Polycythemia vera (9950/3) |
D46._ | Myelodysplastic syndromes (9980, 9982, 9983, 9985, 9986, 9989, 9993) |
D47.02 | Systemic mastocytosis |
D47.1 | Chronic myeloproliferative disease (9963/3, 9975/3) |
D47.3 | Essential (hemorrhagic) thrombocythemia (9962/3) Includes Essential thrombocytosis, idiopathic hemorrhagic thrombocythemia |
D47.4 | Osteomyelofibrosis (9961/3) Includes: Chronic idiopathic myelofibrosis, Myelofibrosis (idiopathic) (with myeloid metaplasia), myelosclerosis (megakaryocytic) with myeloid metaplasia), secondary myelofibrosis in myeloproliferative disease |
D47.Z_ | Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified (9960/3, 9971/3, 9931/3) Note: Effective 1/1/2021, PTLD (9971/3) is no longer reportable (9971/3) |
D47.9 | Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified (9931/3) |
D49.6, D49.7 | Neoplasm of unspecified behavior of brain, endocrine glands and other CNS |
D72.11_ | Hypereosinophilic syndrome {HES} (9964/3) |
K31.A22 | Gastric intestinal metaplasia with high grade dysplasia |
R85.614 | Cytologic evidence of malignancy on smear of anus |
R87.614 | Cytologic evidence of malignancy on smear of cervix |
R87.624 | Cytologic evidence of malignancy on smear of vagina |
R90.0 | Intracranial space-occupying lesion found on diagnostic imaging of central nervous system. |
1 Note: Beginning with cases diagnosed 1/1/2023, pilocytic astrocytoma are coded 9421/1. Cases diagnosed prior to 1/1/2023 are coded 9421/3.
SUPPLEMENTAL CASEFINDING LIST TO BE SCREENED FOR REPORTABLE CONDITIONS
Cases with the following codes should be screened as time allows. Experience has shown that use of this supplemental list increases casefinding for benign brain and CNS, hematopoietic neoplasms and other reportable diseases and treatment related information.
ICD-10-CM Codes | Explanation of Codes |
D06._ | Carcinoma in situ of the cervix |
D13.7 | Benign neoplasm of endocrine pancreas Note: Effective 1/1/2021: Review this code to look for the following which were previously a benign tumor of the pancreas, but is now malignant per ICD-O-3.2
|
D21.4 | Benign neoplasm of connective and other soft tissue of abdomen Note: Effective 1/1/2021: Review this code to look for the following which were previously a benign tumor of the pancreas, but is now malignant per ICD-O-3.2 Gastrointestinal stromal tumor, NOS/GIST, NOS/Gastrointestinal autonomic nerve tumor/GANT/Gastrointestinal pacemaker cell tumor (8936/1, now 8936/3) |
D23.9 | Other benign neoplasm of skin Benign carcinoid tumors of other sites Note: Effective 1/1/2021: Review these codes to look for the following which were previously benign and borderline tumors, but are now malignant per ICD-O-3.2
|
D29.2 | Benign neoplasm of testis Note: Effective 1/1/2024: Review this code to look for the following which was previously a borderline tumor but is now malignant per ICD-O-3.2
|
D35.0_ | Benign neoplasm of adrenal gland Note: Effective 1/1/2021: Review this code to look for the following which was previously a benign (8700/0) tumor of the adrenal gland, but is now malignant per ICD-O-3.2 (8700/3)
|
D37.8 | Neoplasm of uncertain behavior of other specified digestive organs (includes uncertain behavior of pancreas) Note: Effective 1/1/2021: Review this code to look for the following histologies which were previously borderline tumors, but are now malignant per ICD-O-3.2
|
D3A._ | Benign carcinoid tumors Note: Effective 1/1/2021: Review these codes to look for the following which were previously benign or borderline tumors, but are now malignant per ICD-O-3.2
|
D44.6 | Neoplasm of uncertain behavior of carotid body Note: Effective 1/1/2021: Review this code to look for the following histologies which were previously borderline tumors, but are now malignant per ICD-O-3.2
|
D44.7 | Neoplasm of uncertain behavior of aortic body and other paraganglia Note: Effective 1/1/2021: Review this code to look for the following histologies which were previously borderline tumors, but are now malignant per ICD-O-3.2
|
D48.0 | Neoplasm of uncertain behavior of bone and articular cartilage Note: Effective 1/1/2021: Review this code to look for the following histologies which were previously borderline tumors, but are now malignant per ICD-O-3.2
|
D48.1 | Neoplasm of uncertain behavior of connective and other soft tissue of abdomen Note: Effective 1/1/2021: Review this code to look for the following which were previously a benign tumor of the pancreas, but is now malignant per ICD-O-3.2 Gastrointestinal stromal tumor, NOS/GIST, NOS/Gastrointestinal autonomic nerve tumor/GANT/Gastrointestinal pacemaker cell tumor (8936/1, now 8936/3) |
D49.2 | Neoplasm of unspecified behavior of digestive organs (includes unspecified behavior of pancreas) Note: Review this code to look for the following which were previously unknown behavior tumors of the pancreas, but are now malignant tumors per ICD-O-2.3 (Histology 8150/3)
|
D61.810 | Antineoplastic chemotherapy induced pancytopenia |
D64.81 | Anemia due to antineoplastic chemotherapy |
D70.1 | Agranulocytosis secondary to cancer chemotherapy |
D72.10 | Eosinophilia, NOS (Note: Screen for incorrectly coded Chronic eosinophilic leukemia, 9964/3) |
D75.81 | Myelofibrosis (note: this is not primary myelofibrosis [9961/3]) |
E31.2_ | Multiple endocrine neoplasia [MEN] syndromes |
E34.0 | Carcinoid syndrome |
E88.3 | Tumor lysis syndrome (following antineoplastic chemotherapy) |
G89.3 | Neoplasm related pain (acute)(chronic) |
H47.42 | Disorders of optic chiasms in (due to) neoplasm |
H47.52_ | Disorders of visual pathways in (due to) neoplasm |
H47.63_ | Disorders of visual cortex in (due to) neoplasm |
I31.31 | Malignant pericardial effusion in diseases classified elsewhere |
J70.0 | Acute pulmonary manifestations due to radiation |
J70.1 | Chronic and other pulmonary manifestations due to radiation |
J91.0 | Malignant pleural effusion |
K12.31 | Oral mucositis (ulcerative) due to antineoplastic therapy |
K12.33 | Oral mucositis (ulcerative) due to radiation |
K52.0 | Gastroenteritis and colitis due to radiation |
K62.7 | Radiation proctitis |
K62.82 | Dysplasia of anus (AIN I and AIN II) |
K92.81 | Gastrointestinal mucositis (ulcerated) (due to antineoplastic therapy) |
L58._ | Radiodermatitis |
L59.8 | Other disorders of skin and subcutaneous tissue related to radiation |
L59.9 | Disorder of the skin and subcutaneous tissue related to radiation, unspecified |
M31.11 | Hematopoietic stem cell transplantation-associated thrombotic microangioplasty |
M96.2 | Postradiation kyphosis |
M96.5 | Postradiation scoliosis |
N30.4_ | Irradiation cystitis |
N46.024 | Azoospermia due to radiation |
N46.124 | Oligospermia due to radiation |
N52.31-N52.32, N52.34-N52.36 | Post procedural erectile dysfunction (due to prostatectomy, cystectomy, radiation) |
O35.6_ | Maternal care for (suspected) damage to fetus by radiation |
O9A.1_ | Malignant neoplasm complicating pregnancy, childbirth and the puerperium |
P04.11 | Newborn affected by maternal antineoplastic chemotherapy |
P04.12 | Newborn affected by maternal cytotoxic drugs |
Q85.0_ | Neurofibromatosis (nonmalignant) (9540/1) Note: Neurofibromatosis is not cancer. These tumors can be precursors to acoustic neuromas, which are reportable |
R18.0 | Malignant ascites |
R53.0 | Neoplastic (malignant) related fatigue |
R97.21 | Rising PSA following treatment for malignant neoplasm of prostate |
T38.6_ | Poisoning by antigonadotropins, antiestrogens, antiandrogens, not elsewhere classified |
T38.8_, T38.9_ | Poisoning by hormones and their synthetic substitutes |
T45.1_ | Poisoning by, adverse effect of and under dosing of antineoplastic and immunosuppressive drugs |
T45.8_, T45.9_ | Poisoning by primary systemic and hematological agent, unspecified |
T66._ | Unspecified effects of radiation |
T80.81_ | Extravasation of vesicant agent |
T80.82_ | Complication of immune effector cellular therapy
|
T86.0_ | Complications of bone marrow transplant |
Y63.2 | Overdose of radiation given during therapy |
Y84.2 | Radiological procedure and radiotherapy as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure |
Z08 | Encounter for follow-up examination after completed treatment for malignant neoplasm (medical surveillance following completed treatment) |
Z40.0_ | Encounter for prophylactic surgery for risk factors related to malignant neoplasms |
Z42.1 | Encounter for breast reconstruction following mastectomy |
Z48.290 | Encounter for aftercare following bone marrow transplant |
Z48.3 | Aftercare following care for neoplasm |
Z51.0 | Encounter for antineoplastic radiation therapy |
Z51.1_ | Encounter for antineoplastic chemotherapy and immunotherapy |
Z51.5, Z51.89 | Encounter for palliative care and other specified aftercare |
Z79.63_ | Long term (current) use of chemotherapeutic agent |
Z79.64 | Long term (current) use of myelosuppressive agent (hydroxyurea) |
Z79.81_ | Long term (current) use of agents affecting estrogen receptors and estrogen levels |
Z85._ | Personal history of malignant neoplasm |
Z86.00_ | Personal history of in situ neoplasm |
Z86.010 | Personal history of colonic polyps |
Z86.011 | Personal history of benign neoplasm of the brain |
Z86.012 | Personal history of benign carcinoid tumor |
Z92.21, Z92.23, Z92.25, Z92.3 | Personal history of antineoplastic chemotherapy, estrogen therapy, immunosuppression therapy or irradiation (radiation) |
Z92.850 | Personal history of Chimeric Antigen Receptor T-cell therapy
|
Z94.81, Z94.84 | Bone marrow and stem cell transplant status |