Main ContentRaiana dos Anjos Moraes - Curriculum Vitae
PERSONAL DATA
I have a background in physiology and pharmacology with specific training and expertise in cardiovascular and erectile systems, focusing on physiology and pathophysiology of hypertension, diabetes and sexual function. As a PhD student in the laboratory of Dr. Darizy Flavia Silva at Federal University of Bahia (Brazil), I learned basic concepts of vascular control, and this was extended during my training with Dr. R.Clinton Webb as international exchange at University of South Carolina (USA).
EDUCATIONAL BACKGROUND
2022 - Current
Exchange student (Intern) in University of South Carolina, SC, Columbia, USA. Supervisor: R.Clinton Webb
2019 - Current
PhD in Biotechnology in Health and Investigative Medicine, Oswaldo Cruz Foundation (Fiocruz), Salvador, BA, Brazil. Supervisor: Darizy Flavia Silva Amorim de Vasconcelos.
2016 - 2018
Master in pharmacy, Federal University of Bahia (UFBA), Salvador, Brazil. Thesis: Itaconimides derivatives induce relaxation in mesenteric artery and negative inotropism in rats by inhibition of Ca2+ influx. Supervisor: Darizy Flavia Silva Amorim de Vasconcelos. Scholarship: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
2009 - 2016
Undergrad in Pharmacy, Federal University of Bahia, UFBA, Salvador, Brazil
Brazilian Scientific Mobility Program - Science without Borders (2014 – 2015), fully funded scholarship in University of Illinois at Chicago (UIC), Chicago, USA
Scholarship: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
COMPLEMENTARY EDUCATION
2021 - Training in the Use and Management of Laboratory Animals
University of São Paulo, USP, Brazil
2020 - Pharmacology Intensive Course: Cardiovascular Function
Bahia State University, UNEB, Brazil
2020 - I Electrocardiogram Online Course
Academic League of Cardiology of Pará, LAC, Brazil
2019 - Short term course in technological and biological prospecting of natural resources
I Brazilian Symposium of (Bio)Pharmaceutical Innovation (SIMBIFAR), Salvador, Brazil
2017 - Short term course in assessment methods of natural products activity in the cardiovascular system
VI Symposium of Medicinal Plants of Vale do São Francisco, Juazeiro, Brazil
2017 – Course in knowledge in intellectual property, industrial property and search of technological information in patent documents
Oswaldo Cruz Foundation (Fiocruz), Salvador, Brazil.
2017 - Short term course in Univariate statistical analysis Federal University of Bahia (UFBA), Salvador, Brazil
2016 - Short term course in Unraveling the electrocardiogram II Symposium on Cardiovascular Physiology, Sergipe, Brazil
2014 - I Mini course of nephrology
Federal University of Bahia (UFBA), Salvador, Brazil
2013 - Theoretical and practical course of administration of injectable medicines Institute of Galeno, Salvador, Brazil
2012 - Short term course in basic approaches to cancer control National Cancer Institute (INCA), Brazil
2009 - Short term course in Immunosuppressive drugs Federal University of Bahia (UFBA), Salvador, Brazil
RESEARCH PROJECTS
2020 – Current
Study of pharmacological effects of NONO2P, nitric oxide donor complex, on the cardiovascular system from rats
Members: Darizy Flavia Silva Amorim de Vasconcelos (coordinator); Fênix Alexandra de Araujo; Raiana dos Anjos Moraes; Rafael Leonne Cruz de Jesus; Liliane Barreto da Silva; Gabriela Brandao de Carvalho Lima; Daniele Santana de Brito.
2019 – Current
Thermosensitive TRPM8 channels and diabetic erectile dysfunction
Members: Darizy Flavia Silva Amorim de Vasconcelos; R Clinton Webb; Raiana dos Anjos Moraes.
2018 – Current
Evaluation of vascular effects induced by Leandra dasytricha leaf extract in spontaneously hypertensive (SHR) and normotensive (Wistar) rats
Members: Darizy Flavia Silva Amorim de Vasconcelos (coordinator); Fênix Alexandra de Araujo; Quiara Lovatti Alves; Raiana dos Anjos Moraes; Rafael Leonne Cruz de Jesus; Gabriela Brandao de Carvalho Lima; Daniele Santana de Brito.
2018 – Current
Evaluation of the therapeutic potential of coumarin braylin for the treatment of erectile dysfunction associated with hypertension.
Members: Darizy Flavia Silva Amorim de Vasconcelos (coordinator); Fênix Alexandra de Araujo; Raiana dos Anjos Moraes; Rafael Leonne Cruz de Jesus; Gabriela Brandao de Carvalho Lima; Daniele Santana de Brito.
2018 – 2020
Cardiovascular activities of different coumarines: structure-activity relationship study Members: Darizy Flavia Silva Amorim de Vasconcelos (coordinator); José Maria Barbosa Filho; Letícia Oliveira Simões; Quiara Lovati Alves; Carla Fiama de Azevedo Medeiros; Viviane Rodrigues Santana da Hora; Fênix Alexandra de Araujo; Raiana dos Anjos Moraes.
2016 - 2018
Pharmacological profile of five cyclic imides on the cardiovascular system: a focus for structure-activity relationship.
Members: Darizy Flavia Silva Amorim de Vasconcelos (coordinator); Quiara Lovati Alves; Valdir Cechinel-Filho; Carla Fiama de Azevedo Medeiros; Samuel Barbosa Camargo; Viviane Rodrigues Santana da Hora; Raiana dos Anjos Moraes.
2016 – 2018
Antihypertensive potential evaluation of carvacrol complexed with a drug controlled release system: A focus for beta-cyclodextrin
Members: Darizy Flavia Silva Amorim de Vasconcelos (coordinator); Quiara Lovati Alves; Lucindo José Quintans Júnior; Jullyana de Souza Siqueira Quintans; Samuel Barbosa Camargo; Carla Fiama de Azevedo Medeiros; Anderson de Melo Jesus; Liliane Barreto da Silva; Raiana dos Anjos Moraes.
EXTENSION PROJECT
2010-2012
Health Work Education Program (PET-Saúde)
Members: Maria Cristina T. Cangussu (coordinator); Raiana dos Anjos Moraes; Angela de Carvalho Pontes; Joslene Barreto; Cleane Guardiano Leal.
INTERNSHIP
2013- 2014
Antivenom Information Center of Bahia (CIAVE – Bahia)
HONOR
2022 - Gonçalo Moniz Institute, Oswaldo Cruz Foundation (Fiocruz) Category: PhD in progress
2017 - Honorable mention to the work: Itaconimides derivatives induce relaxation in mesenteric artery from rats, VI Symposium of Medicinal Plants of Vale do São Francisco.
GRANT
2021 – 2022 - Sexual Medicine Society of North America Research Grant
PUBLICATIONS
MORAES, RAIANA DOS ANJOS; WEBB, R. CLINTON; SILVA, DARÍZY FLÁVIA. Vascular Dysfunction in Diabetes and Obesity: Focus on TRP Channels. Frontiers in Physiology, v. 12, p. xx, 2021.
SANTOS, W. A.; DOURADO, K. M. C.; ARAÚJO, F. A.; JESUS, R. L. C.; MORAES, R. A.; OLIVEIRA, S. C. D. S.; ALVES, Q. L.; SIMÕES, L. O.; CASAIS-E-SILVA, L. L.; COSTA, R. S.; VELOZO, E. S.; SILVA, D. F. Braylin induces a potent vasorelaxation, involving distinct mechanisms in superior mesenteric and iliac arteries of rats. NAUNYN- SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, v. xx, p. xx-xx, 2020.
ALVES, QUIARA LOVATTI; MORAES, RAIANA DOS ANJOS; FROES, THAMIRES QUADROS; CASTILHO, MARCELO SANTOS; AQUINO DE ARAÚJO, RODRIGO SANTOS; BARBOSA-FILHO, JOSÉ MARIA; MEIRA, CÁSSIO SANTANA; PEREIRA SOARES, MILENA BOTELHO; SILVA, DARÍZY FLÁVIA. Inhibition of intracellular Ca2+ mobilization and potassium channels activation are involved in the vasorelaxation induced by 7-hydroxycoumarin. EUROPEAN JOURNAL OF PHARMACOLOGY, p. 173525, 2020.
BARRETO, LILIANE; CAMARGO, SAMUEL BARBOSA; DOS ANJOS MORAES, RAIANA; MEDEIROS, CARLA FIAMA; DE MELO JESUS, ANDERSON; EVANGELISTA, AFRÂNIO; VILLARREAL, CRISTIANE FLORA; QUINTANS'JÚNIOR, LUCINDO JOSÉ; SILVA, DARÍZY FLÁVIA. Antihypertensive effect of carvacrol is improved after incorporation in β-cyclodextrin as a drug delivery system. Clinical and Experimental Pharmacology & Physiology, 2020.
MORAES, RAIANA DOS ANJOS; ALVES, QUIARA LOVATTI; CAMARGO, SAMUEL BARBOSA; MEDEIROS, CARLA FIAMA DE AZEVEDO; JESUS, ANDERSON DE MELO; DA HORA, VIVIANE RODRIGUES SANTANA; STIZ, DORIMAR SERAFIM; CORRÊA, ROGÉRIO; CECHINEL-FILHO, VALDIR; SILVA, DARIZY FLÁVIA. Itaconimides derivatives induce relaxation in mesenteric artery and negative inotropism by inhibition of CA2+ influx. Pharmacological Reports, 2020.
SILVA, H. R.; COSTA, R. H. F.; PINHEIRO NETO, J. C.; MACEDO JUNIOR, C. A. A.;
NASCIMENTO, P. B.; MORAES, R. A.; PIRES, Y. M. S. Analysis of incidents notified to the National Health Surveillance Notification System (NOTIVISA) in Brazil from 2014 to 2019. RESEARCH, SOCIETY AND DEVELOPMENT, v. 9, p. 1, 2020.
PUBLISHED WORKS IN EVENT ANNALS (SUMMARY)
MORAES R.A., ALVES Q.L., CAMARGO S.B., MEDEIROS C.F.A., HORA V.R.S., JESUS A.D.M., CECHINEL-FILHO V., STIZ D.S., CORRÊA R., VASCONCELOS D.F.S.A. Itaconimides derivatives induce vasodilation, negative inotropism and hypotension. In: 51th Brazilian Congress of Pharmacology and Experimental Therapeutics, 2019, Maceió, AL, Brazil.
LIMA G.B.C., ALVES Q.L., ARAÚJO F.A., JESUS R.L.C., BRITO D.S., GONÇALVES G.O., MORAES R.A., CECHINEL-FILHO V., VASCONCELOS D.F.S.A. Involvement of nitric oxide and potassium channels on the vasorelaxant effect induced by Leandra dasytricha extract. In: 51th Brazilian Congress of Pharmacology and Experimental Therapeutics, 2019, Maceió, AL, Brazil.
HORA V.R.S.; MORAES, R. A; SILVA, D. F. Evaluation of vascular effects induced by different cyclic imides in the superior mesenteric artery: A focus for structure-activity relationship. In: Research, Teaching and Extension Congress, 2018, Salvador, Brazil.
MORAES, R. A; JESUS, A. M; CECHINEL FILHO, V; SILVA, D. F. Itaconimides derivatives induce relaxation in mesenteric artery from rats. In: VI Symposium of Medicinal Plants of Vale do São Francisco, 2017, Juazeiro, BA, Brazil.
SANTOS, M. S.; MENEZES, A. P. O.; CORDEIRO, S.; LEITE, M. C.; GALVAO, V. S.; ANDRADE, J; CAMPOS, A. E. S.; ARAUJO, L.G.; LIMA, V. S.; MORAES, R. A.; BEALL, B. ; REIS, M. G. ; PEDREIRA, J. N. R. Early Nasopharyngeal Carriage of Streptococcus pneumoniae in Brazilian Children. In: 8th International Symposium on Pneumococci and Pneumococcal Diseases, 2012.
PRESENTATION OF WORKS
MORAES R.A., Araújo, F. A., Jesus, R. L. C. Silva, L.B., Meira, C. S., Capinan, J. W. S. Filho, Soares, M. B. P., Sá, D. S., Silva, C. D. S., Silva, D. F. NONO2P, a new nitric oxide donor, induce vasorelaxation in superior mesenteric artery from rats. In: 53th Brazilian Congress of Pharmacology and Experimental Therapeutics, 2021, in the Virtual Format - InEvent Platform, Brazil.
MORAES R.A., ALVES Q.L., CAMARGO S.B., MEDEIROS C.F.A., HORA V.R.S., JESUS A.D.M., CECHINEL-FILHO V., STIZ D.S., CORRÊA R., VASCONCELOS D.F.S.A. Itaconimides derivatives induce vasodilation, negative inotropism and hypotension. In: 51th Brazilian Congress of Pharmacology and Experimental Therapeutics, 2019, Maceió, AL, Brazil.
MORAES, R.A; JESUS, A.M ; CECHINEL FILHO, V; SILVA, D.F. Itaconimides derivatives induce relaxation in mesenteric artery from rats, VI Symposium of Medicinal Plants of Vale do São Francisco, 2017
MORAES, R.A.; PEDREIRA, J.N.R. Antimicrobial Susceptibility of Streptococcus pneumoniae in Cases of Infection and Colonization in Salvador. XXXII Student Research Seminars, 2013.
MORAES, R.A.; MARTINS, K.M.S.; LEITE, M.C.; SANTOS, M.S.; ENCARNACAO, T.J.; LIMA, V.S.; PEDREIRA, J.N.R. Impact of Decavalent Vaccine in Pneumococcal Meningitis in Salvador. XXXI Student Research Seminars, 2012.
MORAES, R.A., SANTOS, M.S., ALMEIDA, L.M., LIMA, V.S., REIS, J.N. Impact of Decavalent Vaccine in Pneumococcal Meningitis in Salvador. VII Seminar of Bacterial Resistance/VI Seminar of Microbial Resistance, 2012.
EXAMINING BOARD
Undergraduate Students
FERREIRA, J.R.D.; ADORNO, E.V.; MORAES, R.A. Participation in Board of Deisiane dos Santos da Silva. Cardiometabolic effects of the use of hormone therapy in transgender: state of the art. 2018. Course Conclusion Paper (Undergraduate Pharmacy) - Federal University of Bahia
SUPERVISION
Another nature guidance
Daniele Santana de Brito. Investigation of the hemodynamic influences of NONO2P on blood pressure blood pressure and heart rate in normotensive and hypertensive rats. 2021. Another Nature guidance (Pharmacy) - Federal University of Bahia
Gabriela Brandão de Carvalho Lima. Characterization of possible mechanisms involved in the vasorelaxant effect induced by NONO2P in mesenteric arteries from normotensive rats. 2021. Another Nature guidance (Pharmacy) - Federal University of Bahia
Viviane Rodrigues Santana da Hora. Evaluation of vascular effects induced by different cyclic imides in the superior mesenteric artery: A focus for structure-activity relationship. 2017. Another Nature guidance (Pharmacy) - Federal University of Bahia
ORGANIZATION OF EVENTS, CONFERENCES AND FAIRS
MORAES, R.A.; BARRETO, N.M.P.V.; LAURIA, P.S.S.; SILVA, L.B.; CAMARGO, S.S.; NASCIMENTO, I.S.; OPRETZKA, L.C.F.; SANTO, R.F.E. Science Fair in Barros Barreto State School. 2017.