Cell and Molecular Biology Research
The Department of Cell and Molecular Biology at UMMC focuses on a variety of research areas. The department is comprised of regular faculty members, instructors, and some faculty with joint appointments in the Cancer Center and Research Institute, and adjunct faculty members from the Departments of Physiology, Preventive Medicine, and Neurology and the School of Nursing.
The faculty use various model systems for their work, such as cell and molecular models, zebrafish, and rodent models. Their studies are supported by grants from the National Institutes of Health and private foundations such as the American Heart Association.
The CMB faculty's research interests focus on these areas:
- the thermodynamics and hydrodynamics of protein-protein interactions
- drug development and delivery
- histone structure and function
- Cajal bodies and RNA processing and their role in mediating diseases such as preeclampsia
- mitochondrial function in the microbiome and heart
- molecular mechanisms of cancer
- mechanisms responsible for tooth development
- mechanisms responsible for sex differences in blood pressure control
- adipose tissue and its role in mediating metabolic disease
- role of microRNAs in mediating adiposity, obesity, and hypertension
- role of lipids in various disease processes
- impact of maternal hyperandrogenemia on cardiometabolic health of the offspring of both sexes
See individual faculty pages for details.
The Cell and Molecular Biology Department also houses four research core facilities located in the Guyton Research Complex:
- Analytical Ultracentrifugation Core
- Animal and Telemetry Core
- Confocal Microscopy Core
- Mitochondrial Research Core
Graduate research mission statement
The overall objective of the PhD program in cell and molecular biology is for each student to achieve competency in both the coursework and research components of the program and develop critical thinking and communication skills. With this knowledge base and skill set, graduating students will be equipped to pursue a variety of different career options.
To ensure that each student meets the objective of the PhD program, many different competencies will be evaluated.