David Stec, PhD

Professor Director, Transgenic Core                       Office: G158; (601) 815-1859 Lab: G154; (601) 815-1366                                           Transgenic Lab: G165 Email

Areas of expertise

• General: Cardiovascular and renal physiology
• Specific: Mechanisms of hypertension, role of heme oxygenase and associated metabolites in the regulation of blood pressure and renal function, role of P450 metabolites of arachidonic acid in the regulation of blood pressure and renal function, role of heme oxygenase and associated metabolites in the regulation of body weight and metabolism

Research methods and techniques

Genetically engineered mouse models; chronic instrumentation of mice for long-term blood pressure and renal function studies; chronic renal intramedullary interstitial infusion in mice; 24 hr measurement of metabolism including oxygen consumption, activity, heat production; antisense DNA targeting; molecular biology methods for study gene expression and activity.

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