David Stec, PhD
Director, Transgenic Core
Office: G158; (601) 815-1859
Lab: G154; (601) 815-1366
Transgenic Lab: G165
Areas of expertise
- General: Cardiovascular and renal physiology
- Specific: Cardiovascular complications of non-alcoholic fatty liver disease (NAFLD); Role of Bilirubin and Biliverdin Reductase in NAFLD; Development of therapeutic strategies to increase plasma bilirubin for the treatment of cardiovascular and metabolic diseases; Role of heme oxygenase and carbon monoxide in the regulation of body weight and metabolism.
Research methods and techniques
Genetically engineered mouse models; chronic instrumentation of mice for long-term blood pressure and renal function studies; chronic renal intramedullary interstitial infusion in mice; 24 hr measurement of metabolism including oxygen consumption, activity, heat production; antisense DNA targeting; molecular biology methods for study gene expression and activity.
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