Alexandre da Silva, PhD

Associate Professor Office: G263 Lab: G253; (601) 984-1829 Email

Areas of expertise

• General: Cardiovascular, neuro and metabolic physiology
• Specific: Neurohumoral control of cardiac function and glucose homeostasis, developmental programming of cardiometabolic and cognitive disorders

Research methods

• Rodent models of cardiovascular and metabolic diseases;
• Chronic instrumentation for long-term cardiovascular and metabolic studies in rodents;
• Pre-clinical echocardiography and catheter-based evaluations of cardiac function;
• Primary and immortalized cell cultures;
• Breeding, genotyping and validation of different Cre-Lox genetically modified mice;

Current projects

• Role of the leptin-brain melanocortin system in regulating cardiac function and protecting the heart against progressive heart failure
• Neurohumoral control of glucose homeostasis in insulin-deficiency diabetes
• Impact of parental obesity on young and adult offspring cardiometabolic profile and cognitive function

For more information

• Biosketch
• Summary of research
• Links to PubMed articles