Zhen Wang, PhD

Assistant Professor Office: G262; (601) 984-1250 Lab: G253; (601) 984-1832 Email

Areas of expertise

• General: Cardiovascular and renal physiology, molecular biology
• Specific: Diabetic nephropathy, leptin signaling pathway and obesity, hypertension

Research methods

• Utilizing chronically instrumented rodents for 24 hr/day computerized-cardiovascular monitoring of BP and HR
• Comprehensive renal, cardiac and metabolic function measurements in chronically instrumented rodents
• Metabolic functions, including appetite, VO2 and energy expenditure measurement
• Chronic IV and intracerebroventricularly (ICV) infusion
• Breeding, genotyping and validation of different Cre-Lox genetically engineered mice
• Molecular, and biochemical assays (RT-PCR, Western Blot, IHC, ELISA, etc.)

Current projects

• Mechanisms of hypertensive diabetic nephropathy: role of mitochondrial dysfunction and ER stress
• Role of negative regulators of leptin signaling (SOCS3) in modulating leptin's actions

For more information

• Biosketch
• Summary of research
  
• Links to PubMed articles