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Oluwabori Adekanye, PhD

Oluwabori Stephen Segun Adekanye
Department of Physiology and Biophysics
University of Mississippi Medical Center
Jackson, Mississippi
Email: oadekanye@umc.edu
LinkedIn: https://www.linkedin.com/in/adekanye-oluwabori-2590151b0?

EDUCATION
Doctor of Philosophy (Ph.D.), Biomedical Sciences
Mississippi State University, Mississippi State, MS, USA
2021 – 2026
Advisor: Dr. Matt K. Ross
Dissertation: Oxidized lipids are inflammatory danger signals. The hydrolytic enzyme carboxylesterase 1 regulates their metabolic fate, thereby shaping macrophage phenotype.

Master of Science (M.S.), Environmental and Applied Physiology
University of Ibadan, Ibadan, Nigeria 2017– 2018

Bachelor of Technology (B.Tech), Human Physiology
Ladoke Akintola University of Technology, Ogbomosho, Nigeria 2009–2015

CONTINUING EDUCATION
Preparing Future Faculty
Center for Teaching and Learning, Mississippi State University
2023 – 2024
The Art of Science Communication
American Society for Biochemistry and Molecular Biology (ASBMB) Summer 2025

PROFESSIONAL EXPERIENCE
Postdoctoral Research Fellow
Department of Physiology and Biophysics
University of Mississippi Medical Center
Jackson, Mississippi
September 2026-Present

Graduate Teaching Assistant
Department of Biological Sciences, Mississippi State University, Starkville, MS, USA Spring 2026
Graduate Research Assistant
Department of Comparative Biomedical Sciences, Mississippi State University, Starkville, MS, USA
2022 – 2026

Graduate Teaching Assistant
Department of Biological Sciences, Mississippi State University, Starkville, MS, USA Jan 2021 – Dec 2021

Graduate Research and Teaching Assistant
Department of Physiology, University of Ibadan, Ibadan, Nigeria 2017 – 2019

Biology and Chemistry Teacher
Akumazi-Umuocha Mixed Secondary School, Delta State, Nigeria 2015 – 2016

Drug Abuse Awareness Team Member
NAFDAC Drug Club, Delta State, Nigeria 2015 –2016

Laboratory Intern
Institute of Advanced Medical Research and Training (IAMRAT), University College Hospital, Ibadan, Nigeria
2013

RESEARCH COMPETENCIES

• Gene modification using lentiviral shRNA constructs
• Mammalian cell culture, maintenance, and preservation
• Quantitative real-time PCR (RT-qPCR)
• DNA/RNA extraction and cDNA synthesis
• Gel electrophoresis and genotyping
• Flow cytometry
• Confocal and fluorescence microscopy
• Liquid chromatography–mass spectrometry (LC-MS)
• Single-cell RNA sequencing analysis
• Lipidomics and metabolomics
• Western blotting, ELISA, and activity-based protein profiling (ABPP)
• Immunoprecipitation and chromatin immunoprecipitation
• Histology and tissue processing
• Enzymatic assays (TUNEL, myeloperoxidase)
• Animal handling and tissue harvesting
• Data analysis (Microsoft Excel, SigmaPlot)
• Scientific illustration (BioRender)

AWARDS, SCHOLARSHIPS, AND GRANTS

• ASBMB Graduate Student Award (2026)
• TAGGs Travel Award (2026)
• Office of Research and Graduate Studies Travel Award (2025)
• 2nd Place, Graduate Research Symposium (Oral), Mississippi State University (2025)
• 2nd Place, Graduate Research Symposium (Oral), Mississippi State University (2024)
• 3rd Place, Graduate Student Oral Presentation, College of Veterinary Medicine Research Day (2024)
• ASBMB Graduate Travel Award (2024)
• Best Graduate Student Poster Presentation, Mississippi Academy of Sciences (2023)
• ORGS Travel Award (2023)
• 2nd Place, Graduate Student Poster, CVM Research Day (2023)
• 2nd Place, Graduate Student Poster, CVM Research Day (2022)
• Doctoral Scholarship, Mississippi State University (2021–2025)
• ASM Future Leaders Mentorship Fellowship (2025–2027)

PUBLICATIONS
Ross, M. K., Borazjani, A., Thrash, H. L., Adekanye, O., & Crow, J. A. (2026). Carboxylesterase 1 contributes to the human macrophage alternative activation response to Th2 cytokine interleukin4. Journal of Leukocyte Biology, 118(6), qiag073.
Borazjani, A., Odom, K., Oluwabori, A., & Ross, M. K. (2026). Thromboxane A2 Synthase is an Off Target of the CES1 Small-Molecule Inhibitor WWL113. Prostaglandins & Other Lipid Mediators, 107074.
Deb, A., Gomez, V., Cheng, Y., Li, Z., Yang, J., Dowllah, I., Nguyen, N., Adekanye, O., Smuder, A.J., Cheng, Z., Liu, B. (2025). Ablation of mitochondrial calcium uniporter alleviates cardiac dysfunction in type 1 diabetes. Cell Calcium.
Adekanye, O., Borazjani, A., Phillips, M. E., & Ross, M. K. (2025). Transcriptomics and
Targeted Metabolomics Reveal That CES1 Ablation in Macrophages Confers a Distinct Inflammatory Phenotype Involving Altered Interleukin-1β, Citrate, and Lipid Levels. The FASEB Journal, 39(14), e70831.
Ogunleye, S. C., Akinsulie, O. C., Aborode, A. T., Olorunshola, M. M., Gbore, D., Oladoye, M., Adekanye, O., ... & Chinyere, E. C. (2024). The re-emergence and transmission of Monkeypox virus in Nigeria: the role of one health. Frontiers in Public Health, 11, 1334238.
Ogunleye, S. C., Olorunshola, M. M., Fasina, K. A., Aborode, A. T., Akinsulie, O. C., Amoo, Adekanye, O., ... & Chinyere, E. C. (2024). Anthrax outbreak: exploring its biological agents and public health implications. Frontiers in Tropical Diseases, 4, 1297896.
*Phillips, M.E.,*Adekanye, O., Borazjani, A., Crow, J.A., Ross, M.K. (2023). CES1 regulates oxylipin metabolism in macrophages. ACS Chemical Biology. (*Co-first authors).
Szafran, B. N., Borazjani, A., Scheaffer, H. L., Crow, J. A., McBride, A. M., Adekanye, O., ... & Ross, M. K. (2022). Carboxylesterase 1d inactivation augments lung inflammation in mice. ACS pharmacology & translational science, 5(10), 919-931.
Ige, A. O., Adekanye, O. S., & Adewoye, E. O. (2023). Intermittent exposure to green and white light-at-night activates hepatic glycogenolytic and gluconeogenetic activities in male Wistar rats. Journal of Basic and Clinical Physiology and Pharmacology, 34(4), 451-458.

BOOK CHAPTERS
Kehinde, B.A., Igiehon, O., Adekanye, O., Majid, I. (2023). Onion Sprouts. In Advances in Plant Sprouts. Springer.
Kehinde, B.A., Igiehon, O., Adekanye, O., Majid, I. (2023). Clover and Alfalfa Sprouts. In Advances in Plant Sprouts. Springer.

PRESENTATIONS (ORAL)
Adekanye, O., Borazjani, A., Ross, M.K. (August 2025). Caspase-1 downstream of NLRP3 inflammasome is more highly expressed and catalytically active in CES1KD macrophages. CVM Research Day, Mississippi State University.
Kehinde, B., Adekanye, O., Taiwo, M. (October 2024). Environmental pollution by food wastes and by-products: probiotic valorization. AIChE Annual Meeting.
Adekanye, O., Borazjani, A., Ross, M.K. (October 2024). CES1 inactivation initiates NLRP3 inflammasome activation. Graduate Research Symposium, Mississippi State University.
Adekanye, O., Borazjani, A., Ross, M.K. (August 2024). CES1 inactivation disrupts TCA cycle and promotes pro-inflammatory phenotype. CVM Research Day.
Adekanye, O., Borazjani, A., Ross, M.K. (March 2024). CES1 knockdown promotes proinflammatory phenotype. ASBMB Annual Meeting.
Adekanye, O., Borazjani, A., Ross, M.K. (February 2024). CES1 knockdown disrupts citric acid metabolism similar to M1 macrophages. Graduate Research Symposium.
Adekanye, O., Borazjani, A., Ross, M.K. (October 2023). Transcriptomic analysis of CES1 knockdown macrophages. Graduate Research Symposium.
Adekanye, O., Borazjani, A., Ross, M.K. (July 2023). CES1 regulates inflammatory cytokines in human macrophages. Mississippi Academy of Sciences.

PRESENTATIONS (POSTER)
Adekanye, O., Borazjani, A., Ross, M.K. (March 2026). Anti-inflammatory markers in CES1deficient macrophages. ASBMB Annual Meeting.
Adekanye, O., Borazjani, A., Ross, M.K. (November 2025). Lipid peroxidation triggers IL-1β release. Society of Toxicology.
Adekanye, O., Borazjani, A., Ross, M.K. (October 2025). Lipid peroxidation triggers IL-1β release. Graduate Research Symposium.
Adekanye, O., Borazjani, A., Ross, M.K. (April 2025). CES1 inactivation alters macrophage metabolism and plasticity. ASBMB Annual Meeting.
Deb, A., et al. (February 2025). Mitochondrial calcium uniporter and cardiomyopathy. Biophysical Society.
Adekanye, O., Borazjani, A., Ross, M.K. (November 2024). CES1 inactivation and inflammasome activation. ASM Regional Meeting.
Adekanye, O., Borazjani, A., Ross, M.K. (February 2024). CES1 knockdown increases citrate and alters immunophenotype. Mississippi Academy of Sciences.
Adekanye, O., Borazjani, A., Ross, M.K. (November 2023). Transcriptomic signatures of CES1 knockdown. ASM Meeting.
Goff, G., Adekanye, O., et al. (August 2023). Chlorpyrifos and serine hydrolases. MSU Undergraduate Research Symposium.
Adekanye, O., Borazjani, A., Ross, M.K. (July 2023). CES1 regulates prostaglandins in macrophages. Mississippi Academy of Sciences.
Phillips, M., Adekanye, O., et al. (April 2023). Hydrolytic metabolism of arachidonic acidcontaining TAGs. CVM Research Day.
Adekanye, O., Phillips, M., Borazjani, A., Ross, M.K. (March 2023). CES1 regulates lipid metabolism. ASBMB Annual Meeting.
Deb, A., Adekanye, O., et al. (2023). Mitochondrial-associated membranes in arrhythmias. Biophysical Journal.
Adekanye, O., Borazjani, A., Ross, M.K. (February 2023). CES1 modifies macrophage phenotype. Mississippi Academy of Sciences.
Deb, A., Adekanye, O., et al. (October 2022). Calcium-dependent arrhythmias. American Heart Association.
Adekanye, O., Borazjani, A., Ross, M.K. (October 2022). CES1 modifies macrophage phenotype. Graduate Research Symposium.
Adekanye, O., Borazjani, A., Ross, M.K. (August 2022). CES1 regulates lipid metabolism. CVM Research Day.
Wonnacott, C., Adekanye, O., et al. (August 2022). Carboxylesterase 1d in lung inflammation. CVM Research Day.

CERTIFICATIONS

• Responsible Conduct of Research (2022)
• CITI Program – Working with the IACUC (2021)
• National Youth Service Corps (NYSC), Nigeria (2015)

LEADERSHIP & SERVICE

• Co-Facilitator, ASBMB Art of Science Communication (2026)
• Judge, ASBMB Undergraduate Poster Competition (2024–2026)
• Reviewer, MSU Endeavors Journal (2024)
• Graduate Student Association Representative (2024)
• Undergraduate Research Symposium Evaluator (2023–2024)
• MSU Leadership and Community Engagement (MLK Day) (2021–2024)
• Member, National Drug Law Enforcement Agency Drug-Free Club (2015–2016)
• Co-Facilitator, The Art of Science Communication American Society for Biochemistry and Molecular Biology (ASBMB) Summer 2026

PROFESSIONAL MEMBERSHIPS

• American Society for Biochemistry and Molecular Biology (ASBMB)
• American Society for Microbiology (ASM)
• Mississippi Academy of Sciences (MAS)