Ji Li, PhD

Professor Office: G551-03; (601) 815-8995 Lab: G554; (601) 984-1839 Email

Areas of Expertise

• General: Cardiovascular Pharmacology and Physiology, Neuroinflammation and neurometabolic integration
• Specific: Signal transduction, metabolic regulation, myocardial ischemia and reperfusion, heart failure, cardiorenal syndrome, traumatic brain injury, epilepsy, Alzheimer's disease

Research methods and techniques

Surgical approaches to generate animal models of myocardial infarction, heart failure, cardiorenal syndrome, traumatic brain injury. Echocardiography measures cardiac systolic and diastolic functions under physiological and pathological conditions. Quantitative electroencephalography for measurement of traumatic brain injury, epilepsy, and Alzheimer’s disease related dementia. A working heart perfusion system with radioactive glucose and oleate to determine cardiac metabolism under physiological and pathological conditions. IonOptix myocyte calcium and contractility systems to determine contractile functions of cardiomyocytes in response to pathological challenge. Seahorse XF Cell Mito Stress Test measures alterations in mitochondrial energy metabolism under physiological or pathological conditions. 10x Genomics Single Cell Technique and common biochemical/molecular analysis investigate the signal transduction of heart and brain in response to pathological challenge in aging.

For more information

• Biosketch
• Summary of Research
• Links to PubMed articles