Metabolic Phenotyping Core

Main Content

Metabolic Core Equipment

Promethion Metabolic Measurement System - Sable System

SableHD equipment.jpgThe Promethion Respiratory System for mice and rats synchronously measures energy expenditure, respiratory quotient (RQ), oxygen consumption (VO2), dioxide production (VCO2), heat production activity and behavioral information, yielding a highly-resolved and rich data stream. The SableHD High Definition platform updates once per second for all sensors in every cage - including position, food and water intake, wheel running, body mass and more, sleep time - creating a richer data stream, compliant raw data storage and analytical flexibility.  

Sable HD monitorKey components

  • Promethion core rack mount instrumentation includes:
    • Triple gas single path analyzer
    • 16-channel flow generator and multiplexer
    • Promethion IM-3 interface module, including onboard computer and memory
  • Vacuum pump
  • Precision mass monitors
  • Magnetic mount hood hopper
  • Magnetic mount rater bottle with sipper yube
  • Data acquisition and analysis software
  • Body mass measurement - enrichment accessory
  • Access control unit
  • 3-D IR beam break array
  • Activity detector vibration sensor pad
  • Desktop computer with monitor
  • Running wheel
  • Environmental sensor array

Columbus Instruments - Metabolic Measurement System

Columbus equipmentColumbus Instrument’s Comprehensive Lab Animal Monitoring System (CLAMS) measures energy expenditure, respiratory quotient (RQ), oxygen consumption (VO2), dioxide production (VCO2), heat production and body temperature. CLAMS serves as a platform onto which animal may add activity, feeding, drinking and telemetry allowing 24-hour, automated, non-invasive measurements of several physiological and behavioral parameters.

Key components
  • CLAMS core rack mount instrumentation includes:
    • Triple gas single path analyzer
    • 8-channel flow generator
  • Vacuum pump
  • Precision mass monitors
  • Food hopper
  • Water bottle with sipper tube
  • Data acquisition and analysis software
  • PDT – 400 E-Mitter to measure body temperature in mice
  • Temperature and humidity chamber for mice
  • Access control unit
  • 3-D IR beam break array
  • Activity detector vibration sensor pad
  • Desktop computer with monitor
  • Environmental sensor array

AccusCan - Metabolic Measurement System

AccusCan equipmentAccusCan Metabolic Measurement System measures energy expenditure, respiratory quotient (RQ), oxygen consumption (VO2), dioxide production (VCO2), heat production, food and water intake.

Key components

  • AccusCan core rack mount instrumentation includes:
    • Triple Gas Single Path Analyzer
    • 4-channel Flow Generator
  • Vacuum pump
  • Precision mass monitors
  • Food hopper
  • Water bottle with sipper tube
  • Data acquisition and analysis software
  • 3-D IR beam break array
  • Activity detector vibration sensor pad
  • Desktop computer with monitor

EchoMRI 4-in-1 System

EchoMRI The EchoMRI 4-in-1-700 Analyzers measures precise body composition including fat, lean, free water, and total water masses for live animals. Scanning takes 0.5 – 3.2 minutes, depending on the precision options.

Key components

  • Horizontal bore for rats up to 700 grams (500 and 700 grams)
  • Vertical bore for mice up to 100 grams
  • Vertical bore for organ or tissue up 7 grams
  • Vertical bore for biopsy samples up to 0.3 grams
  • Water bottle with sipper tube
  • Data acquisition and analysis