Manju George

Manju George

Assistant Professor

Department:
SPH-Population Health Science

Email:
mgeorge@umc.edu

Work Phone:
(601) 984-5560

Education

College of Veterinary and Animal Sciences, Mannuthy, Thrisoor, Kerala India, BVSc & AH, Veterinary Medicine and Animal Husbandry1995

Publications

Randomized Controlled Trial

Hitchcock KE, Miller ED, Shi Q, Dixon JG, Gholami S, White SB, Wu C, Goulet CC, George M, Jee KW, Wright CL, Yaeger R, Shergill A, Hong TS, George TJ, O'Reilly EM, Meyerhardt JA, Romesser PB, Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal cancer: evaluating radiation, ablation, and surgery (ERASur). BMC cancer, 2024 Feb 13;24(1):2012024

Consensus Development Conference

Godfrey EL, Mahoney F, Bansal VV, Su DG, Hanna DN, Lopez-Ramirez F, Baron E, Turaga KK, Benson AB, Cusack J, Winer JH, Gunderson CG, Misdraji J, Shah R, Magge DR, Solsky I, Eng C, Eng OS, Shergill A, Shen JP, Foote MB, Peritoneal Surface Malignancies Consortium Group, Consensus guideline for the management of patients with appendiceal tumors, part 1: Appendiceal tumors without peritoneal involvement. Cancer, 2025 Jul 1;131(13):e358672025

Journal Article

Sekar P, Johnson WV, George M, Breininger A, Parsons HM, Vogel RI, Blaes AH, Gupta A, "The biggest challenge is there's never a routine": a qualitative study of the time burdens of cancer care at home. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025 Jan 27;33(2):802025
Alvarez J, Zambare W, George M, Garcia R, Gallagher P, Kitchens C, Bercz A, Kim MJ, Romesser PB, Cercek A, Garcia-Aguilar J, Sanoff H, George TJ, Hong TS, Yothers G, Philip PA, Al Baghdadi T, Alese OB, Shergill A, O'Reilly EM, Meyerhardt JA, Horvat N, Dasari A, Hall WA, Shi Q, Schrag D, Smith JJ, Utilizing Patient Input in Rectal Cancer Trial Design. Journal of the National Cancer Institute, 2025 Jul 1;117(7):1421-14282025
Schultz KS, Bansal VV, Wach MM, Bhutiani N, Godley FA 4th, Wang JJ, Waheed MT, Buchheit JT, Papai E, Campbell S, Schleimer LE, Su DG, Turaga KK, Gunderson CG, White MG, Uppal A, Raghav KPS, Labow DM, Sarpel U, Shergill AP, Shen JP, Eng C, Foote MB, Baumgartner JM, Peritoneal Surface Malignancies Consortium Group, Consensus guideline for the management of colorectal cancer with peritoneal metastases. Cancer, 2025 Jul 1;131(13):e358692025
Godfrey EL, Mahoney F, Bansal VV, Su DG, Hanna DN, Lopez-Ramirez F, Baron E, Turaga KK, Benson AB 3rd, Setia N, Winer JH, Gunderson CG, Shah R, Magge DR, Solsky I, Eng C, Eng OS, Shergill A, Shen JP, Misdraji J, Foote MB, Luo W, Peritoneal Surface Malignancies Consortium Group, Consensus guideline for the management of patients with appendiceal tumors, part 2: Appendiceal tumors with peritoneal involvement. Cancer, 2025 Jul 1;131(13):e358742025
Schultz KS, Bansal VV, Wach MM, Bhutiani N, Godley FA 4th, Wang JJ, Waheed MT, Buchheit JT, Papai E, Campbell S, Schleimer LE, Su DG, Turaga KK, Gunderson CG, White MG, Uppal A, Raghav KPS, Labow DM, Sarpel U, Shergill AP, Shen JP, Eng C, Foote MB, Baumgartner JM, Peritoneal Surface Malignancies (PSM) Consortium Group, Consensus Guideline for the Management of Colorectal Cancer with Peritoneal Metastases. Annals of surgical oncology, 2025 Jun 25;2025
Godfrey EL, Mahoney F, Bansal VV, Su DG, Hanna DN, Lopez-Ramirez F, Baron E, Turaga KK, Benson AB 3rd, Cusack J, Winer JH, Gunderson CG, Misdraji J, Shah R, Magge DR, Solsky I, Eng C, Eng OS, Shergill A, Shen JP, Foote MB, Peritoneal Surface Malignancies (PSM) Consortium Group, Consensus Guideline for the Management of Patients with Appendiceal Tumors, Part 1: Appendiceal Tumors Without Peritoneal Involvement. Annals of surgical oncology, 2025 Jun 25;2025
Godfrey EL, Mahoney F, Bansal VV, Su DG, Hanna DN, Lopez-Ramirez F, Baron E, Turaga KK, Benson AB 3rd, Setia N, Winer JH, Gunderson CG, Shah R, Magge DR, Solsky I, Eng C, Eng OS, Shergill A, Shen JP, Misdraji J, Foote MB, Luo W, Peritoneal Surface Malignancies (PSM) Consortium Group, Consensus Guideline for the Management of Patients with Appendiceal Tumors, Part 2: Appendiceal Tumors with Peritoneal Involvement. Annals of surgical oncology, 2025 Jun 25;2025
Kagalwalla S, Tsai AK, George M, Waldock A, Davis S, Jewett P, Vogel RI, Ganguli I, Booth C, Dusetzina SB, Rocque GB, Blaes AH, Gupta A, Consuming Patients' Days: Time Spent on Ambulatory Appointments by People With Cancer. The oncologist, 2024 May 3;29(5):400-4062024
Alvarez JA, Shi Q, Dasari A, Garcia-Aguilar J, Sanoff H, George TJ, Hong T, Yothers G, Philip P, Nelson G, Al Baghdadi T, Alese OB, Zambare W, Omer D, Verheij FS, Bercz A, Kim MJ, Buckley J, Williams H, George M, Garcia R, Gallagher P, O'Reilly EM, Meyerhardt JA, Crawley J, Shergill A, Horvat N, Romesser PB, Hall W, Smith JJ, Alliance A022104/NRG-GI010: The Janus Rectal Cancer Trial: a randomized phase II/III trial testing the efficacy of triplet versus doublet chemotherapy regarding clinical complete response and disease-free survival in patients with locally advanced rectal cancer. BMC cancer, 2024 Jul 26;24(1):9012024
Scott AJ, Kennedy EB, Berlin J, Brown G, Chalabi M, Cho MT, Cusnir M, Dorth J, George M, Kachnic LA, Kennecke HF, Loree JM, Morris VK, Perez RO, Smith JJ, Strickland MR, Gholami S, Management of Locally Advanced Rectal Cancer: ASCO Guideline. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2024 Oct;42(28):3355-33752024
Gupta A, Johnson WV, Henderson NL, Ogunleye OO, Sekar P, George M, Breininger A, Kyle MA, Booth CM, Hanna TP, Rocque GB, Parsons HM, Vogel RI, Blaes AH, Patient, Caregiver, and Clinician Perspectives on the Time Burdens of Cancer Care. JAMA network open, 2024 Nov 4;7(11):e24476492024
Kennecke HF, Auer R, Cho M, Dasari NA, Davies-Venn C, Eng C, Dorth J, Garcia-Aguilar J, George M, Goodman KA, Kreppel L, Meyer JE, Monzon J, Saltz L, Schrag D, Smith JJ, Zell JA, Das P, National Cancer Institute Rectal-Anal Task Force, NCI Rectal-Anal Task Force consensus recommendations for design of clinical trials in rectal cancer. Journal of the National Cancer Institute, 2023 Dec 6;115(12):1457-14642023
Hitchcock KE, Miller ED, Shi Q, Dixon JG, Gholami S, White SB, Wu C, Goulet CC, George M, Jee KW, Wright CL, Yaeger R, Shergill A, Hong TS, George TJ, O'Reilly EM, Meyerhardt JA, Romesser PB, Alliance for Clinical Trials in Oncology (Alliance) trial A022101/NRG-GI009: A pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal cancer: evaluating radiation, ablation, and surgery (ERASur). Research square, 2023 Dec 23;2023
Araujo L, Rebic N, Dau H, Brotto L, George M, De Vera MA, Reproductive Health Experiences of Females Diagnosed with Young-Onset Colorectal Cancer: A Multi-Method Cross-Sectional Survey. Current oncology (Toronto, Ont.), 2022 Jan 21;29(2):465-4782022
Kasi A, Dotan E, Poage GM, Catteau A, Vernerey D, George M, Barzi A, Impact of Immunoscore on the Management of Stage II Colon Cancer Patients: A Physician Survey. Cancers, 2021 Oct 30;13(21)2021
Bhattacharyya S, Rainey MA, Arya P, Mohapatra BC, Mushtaq I, Dutta S, George M, Storck MD, McComb RD, Muirhead D, Todd GL, Gould K, Datta K, Waes JG, Band V, Band H, Corrigendum: Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Scientific reports, 2017 Mar 23;7:423202017
Bhattacharyya S, Rainey MA, Arya P, Mohapatra BC, Mushtaq I, Dutta S, George M, Storck MD, McComb RD, Muirhead D, Todd GL, Gould K, Datta K, Gelineau-van Waes J, Band V, Band H, Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Scientific reports, 2016 Feb 17;6:207272016
Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Developmental biology, 2015 Dec 1;408(1):41-552015
Bailey TA, Luan H, Tom E, Bielecki TA, Mohapatra B, Ahmad G, George M, Kelly DL, Natarajan A, Raja SM, Band V, Band H, A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells. The Journal of biological chemistry, 2014 Oct 31;289(44):30443-304582014
Buggia-Prévot V, Fernandez CG, Udayar V, Vetrivel KS, Elie A, Roseman J, Sasse VA, Lefkow M, Meckler X, Bhattacharyya S, George M, Kar S, Bindokas VP, Parent AT, Rajendran L, Band H, Vassar R, Thinakaran G, A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production. Cell reports, 2013 Dec 26;5(6):1552-632013
Posey AD Jr, Pytel P, Gardikiotes K, Demonbreun AR, Rainey M, George M, Band H, McNally EM, Endocytic recycling proteins EHD1 and EHD2 interact with fer-1-like-5 (Fer1L5) and mediate myoblast fusion. The Journal of biological chemistry, 2011 Mar 4;286(9):7379-882011
George M, Rainey MA, Naramura M, Foster KW, Holzapfel MS, Willoughby LL, Ying G, Goswami RM, Gurumurthy CB, Band V, Satchell SC, Band H, Renal thrombotic microangiopathy in mice with combined deletion of endocytic recycling regulators EHD3 and EHD4. PloS one, 2011 Mar 9;6(3):e178382011
George M, Rainey MA, Naramura M, Ying G, Harms DW, Vitaterna MH, Doglio L, Crawford SE, Hess RA, Band V, Band H, Ehd4 is required to attain normal prepubertal testis size but dispensable for fertility in male mice. Genesis (New York, N.Y. : 2000), 2010 May;48(5):328-422010
Rainey MA, George M, Ying G, Akakura R, Burgess DJ, Siefker E, Bargar T, Doglio L, Crawford SE, Todd GL, Govindarajan V, Hess RA, Band V, Naramura M, Band H, The endocytic recycling regulator EHD1 is essential for spermatogenesis and male fertility in mice. BMC developmental biology, 2010 Apr 2;10:372010
Gudmundsson H, Hund TJ, Wright PJ, Kline CF, Snyder JS, Qian L, Koval OM, Cunha SR, George M, Rainey MA, Kashef FE, Dun W, Boyden PA, Anderson ME, Band H, Mohler PJ, EH domain proteins regulate cardiac membrane protein targeting. Circulation research, 2010 Jul 9;107(1):84-952010
Sengupta S, George M, Miller KK, Naik K, Chou J, Cheatham MA, Dallos P, Naramura M, Band H, Zheng J, EHD4 and CDH23 are interacting partners in cochlear hair cells. The Journal of biological chemistry, 2009 Jul 24;284(30):20121-92009
Chung BM, Raja SM, Clubb RJ, Tu C, George M, Band V, Band H, Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src. BMC cell biology, 2009 Nov 30;10:842009
George M, Ying G, Rainey MA, Solomon A, Parikh PT, Gao Q, Band V, Band H, Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans. BMC cell biology, 2007 Jan 18;8:32007
George M, Venkataramanan R, Pattnaik B, Sanyal A, Gurumurthy CB, Hemadri D, Tosh C, Sequence analysis of the RNA polymerase gene of foot-and-mouth disease virus serotype Asia1. Virus genes, 2001 Jan;22(1):21-62001
George M, Venkataramanan R, Gurumurthy CB, Hemadri D, The non-structural leader protein gene of foot-and-mouth disease virus is highly variable between serotypes. Virus genes, 2001 Jun;22(3):271-82001
Pattnaik B, Sanyal A, George M, Tosh C, Hemadri D, Venkataramanan R, Evaluation of primers for PCR amplification of RNA polymerase gene sequences of foot-and-mouth disease virus. Acta virologica, 1997 Dec;41(6):333-61997
Gurumurthy CB, Sanyal A, Venkataramanan R, Tosh C, George M, Hemadri D, Genetic diversity in the VP1 gene of foot-and-mouth disease virus serotype Asia 1. Archives of virology, 2002;147(1):85-102

Editorial

Felder S, Frakes J, George M, Rosen A, Sahin IH, Which Treatment for Which Patient: Rectal Cancer Management After PROSPECT Trial. Oncology (Williston Park, N.Y.), 2024 May 13;38(5):187-1902024
Banerjee R, George M, Gupta A, Maximizing Home Time for Persons With Cancer. JCO oncology practice, 2021 Sep;17(9):513-5162021

Presentations

Poster Presentation, Communication of cancer biomarker testing results: what patients need., ASCO, San Francisco CA01/2025
National and International Invited Seminars/Lectures, From Diagnosis to Treatment to Survivorship-The patient Perspective, ASCO, San Francisco, CA01/2024
Poster Presentation, Twitterchats as a means to educate patients with CRC and caregivers, and stimulate collaborations, ASCO, San Francisco CA01/2023
Poster Presentation, Colontown University: Patient-created disease education, ASCO, San Francisco CA01/2022
Poster Presentation, Impact and utility of COLONTOWN, an online CRC patient and caregiver support group in clinical trial design, ASCO, San Francisco CA01/2021
Poster Presentation, Subverting trafficking of ErbB2 to improve the efficacy of targeted therapies, DoD, Era of Hope Conference, Orlando, FL08/2011
Poster Presentation, Severe Glomerular Pathology in Mice Lacking Glomerular Endothelium-Enriched Endocytic Regulator Ehd3 and the Related
Gene Ehd4, American Society for Nephrology, Denver, CO
11/2010
Poster Presentation, Ehd4 is Required to Attain Normal Prepubertal Testis Size But Dispensable for Fertility in Male Mice, Gordon research Conference, Proctor Academy, Andover08/2010