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John D. Isaacs  Jr., MD

John D. Isaacs Jr., MD

Specialties: Reproductive Endocrinology and Infertility

Gender: Male

Biography: After receiving the B.A. in biological science from the University of Mississippi in 1984, Isaacs earned the M.D. at UMMC in 1989. He had an ob-gyn internship and residency here from 1989-93 and completed a reproductive endocrinology fellowship in the Department of Obstetrics and Gynecology at Washington University Medical Center, St. Louis, Missouri, in 1995. Before entering private practice, Isaacs served as an assistant professor of ob-gyn in the Division of Reproductive Endocrinology at UMMC from 1995-99. An ad hoc reviewer for the journals Fertility and Sterility and the Journal of the Mississippi State Medical Association and a special reviewer for Obstetrics and Gynecology, Isaacs is a fellow of the American College of Obstetricians and Gynecologists and is an active member of several professional organizations. He has authored or co-authored 18 articles in peer-reviewed professional publications, seven book chapters, 16 abstracts, and has made numerous presentations at scientific meetings throughout the U.S. and Canada.

My Approach to Healthcare

“I have discovered over the years that listening to my patients is the most important thing I can do as a doctor. I try to understand a patient’s unique situation and tailor a plan of treatment that meets their individual needs. We have treatments that can help the majority of couples achieve their dream of having a family but there are many ways to navigate the options available. I try to educate patients about their options and help them make the best choice for their situation."

Practice Locations

Accepted Insurance Plans

The University of Mississippi Medical Center accepts all plans, but may not be an in-network provider with your plan. We encourage you to contact your insurer and ask if the plan is in network with UMMC. Always contact your insurance carrier for specific coverage information.

Network Participation - 2026

MississippiCAN and CHIP [Managed Care programs promulgated by the Mississippi Division of Medicaid]

  • Molina Healthcare of Mississippi, Inc.
  • Magnolia Health (Centene)
  • TrueCare

Affordable Care Act (ACA) Marketplace [Individual plans offered on healthcare.gov]

  • Ambetter from Magnolia Health (Centene)
  • Molina Healthcare of Mississippi, Inc.
  • UHC Marketplace (Madison only)

Medicare Advantage

  • Devoted Health Plans: PPO, HMO, DSNP, CSNP
  • HealthSpring Plans: PPO, HMO, DSNP
  • Humana: PPO, HMO, DSNP, CSNP, ISNP
  • United Healthcare Plans: PPO, HMO, DSNP, CSNP, ISNP
  • WellCare (Centene) Plans: PPO, HMO, DSNP

Commercial - Group and Individual

  • Aetna Plans: PPO, HMO [Includes all facilities except UMMC Madison]
  • BCBSMS Plans: BlueCardPPO, State Health Plan (AHS), Federal Employee Plan (FEP)
  • Cigna Plans: PPO, HMO
  • United Healthcare Plans: PPO, HMO (Includes plans administered by UMR, UnitedHealth Group's wholly owned third-party administrator (TPA) subsidiary)

Transplant Only Networks

  • Optum Plan: Commercial • Programs: Solid Organ, BMT, VAD
  • Emerging Therapy Solutions (ETS) Plan: Commercial • Programs: Solid Organ, BMT, CAR-T, VAD
  • Interlink Plan: Commercial • Programs: Solid Organ, BMT, CAR-T
  • Celtic Plans: Ambetter, WellCare, Magnolia Health MississippiCAN, Magnolia Health CHIP • Programs: Solid Organ, BMT
  • Cigna Lifesource Plan: Commercial • Programs: Solid Organ, BMT, CAR-T, VAD

Dental

  • Avesis Plan: MississippiCAN and CHIP (TrueCare)
  • Always Care/Unum Plan: Commercial

Vision

  • Avesis Plan: MississippiCAN and CHIP (TrueCare)
  • Always Care/Unum Plan: Commercial

Rental Networks (Utilized by self-funded employer group plans and third-party administrators (TPAs))

  • Mississippi Physicians Care Network (MPCN) [If MPCN is present on a Member/Subscriber ID, all UMMC facilities and providers are in-network regardless of TPA.]
  • First Choice Health Plan
  • Claritev (formerly Multiplan)
  • Zelis

Government Programs

  • Humana Military Plan: Tricare
  • United Healthcare Plan: Veterans Affairs Community Care Networks

Plans and Payors UMMC is not in-network with as of April 1, 2026

  • Oscar Health Plan: ACA Marketplace [Final negotiations taking place now. Anticipate in-network participation, effective June 1, 2026.]
  • Cigna (Connect EPO) Plan: ACA Marketplace
  • American Health Advantage Plan: Medicare Advantage
  • Patrius Health (BCBSMS) Plan: Medicare Advantage
  • Aetna Plan: Medicare Advantage

Education

Board Certification: Obstetrics & Gynecology, Reproductive Endocrinology; Obstetrics and Gynecology
Fellowship:Washington University Medical School
Internship:University of Mississippi Medical Center
Medical Education:University of Mississippi School of Medicine
Residency:University of Mississippi Medical Center