Maria Clarissa Yasmin "Maria Clarissa" O. Tio, MD

Maria Clarissa Yasmin "Maria Clarissa" O. Tio, MD

Assistant Professor

Department:
SOM-Medicine-NEPHROL

Email:
mctio@umc.edu

Academic Appointments or Other Previous Appointments

Assistant Professor, School of Medicine, Department of Medicine

Sponsored Program Funding

Extramural, Mississippi Center for Clinical and Translational Research Scholars Program01/2022 - Present

Publications

Review

Tio MC, Shafi T, Zhu X, Kalantar-Zadeh K, Chan A, Nguyen L, Traditions and innovations in assessment of glomerular filtration rate using creatinine to cystatin C. Current opinion in nephrology and hypertension, 2023 Jan 1;32(1):89-972023

Journal Article

Hamid A, Khan Minhas AM, Rizwan AM, Kamimura D, Tio MC, Claudio CH, Pandey A, Mentz R, Nambi V, Jones DW, Hall JE, Butler J, Hall ME, Independent and Joint Associations of Obesity and Hypertension on Incident Heart Failure: A Pooled Cohort Analysis. Mayo Clinic proceedings, 2025 Jul 4;2025
Tio MC, Butler J, Zhu X, Obi Y, Yen TE, Kalantar-Zadeh K, Streja E, Dossabhoy NR, Hall ME, Shafi T Individualized Risk of CKD Progression among US Adults J Am Soc Nephrol. 2024 Aug 1;35(8):1076-10832024
Tio MC, Zhu X, Lirette S, Rule AD, Butler K, Hall ME, Dossabhoy NR, Mosley T, Shafi T, External Validation of a Novel Multimarker GFR Estimating Equation. Kidney360, 2023 Dec 1;4(12):1680-16892023
Ermer T, Nazzal L, Tio MC, Waikar S, Aronson PS, Knauf F, Oxalate homeostasis. Nature reviews. Nephrology, 2023 Feb;19(2):123-1382023
Gupta S, Garcia-Carro C, Prosek JM, Glezerman I, Herrmann SM, Garcia P, Abudayyeh A, Lumlertgul N, Malik AB, Loew S, Beckerman P, Renaghan AD, Carlos CA, Rashidi A, Mithani Z, Deshpande P, Rangarajan S, Shah CV, Seigneux S, Campedel L, Kitchlu A, Shin DS, Coppock G, Ortiz-Melo DI, Sprangers B, Aggarwal V, Benesova K, Wanchoo R, Murakami N, Cortazar FB, Reynolds KL, Sise ME, Soler MJ, Leaf DE, ICPi-AKI Consortium Investigators, Shorter versus longer corticosteroid duration and recurrent immune checkpoint inhibitor-associated AKI. Journal for immunotherapy of cancer, 2022 Sep;10(9)2022
Gupta S, Strohbehn IA, Wang Q, Hanna PE, Seethapathy R, Prosek JM, Herrmann SM, Abudayyeh A, Malik AB, Loew S, Carlos CA, Chang WT, Beckerman P, Mithani Z, Shah CV, Renaghan AD, de Seigneux S, Campedel L, Kitchlu A, Shin DS, Coppock G, Lumlertgul N, Garcia P, Ortiz-Melo DI, Rashidi A, Sprangers B, Aggarwal V, Benesova K, Jhaveri KD, Cortazar FB, Weins A, Zuo Y, Mooradian MJ, Reynolds KL, Leaf DE, Sise ME, ICPi-AKI Consortium, Acute kidney injury in patients receiving pembrolizumab combination therapy versus pembrolizumab monotherapy for advanced lung cancer. Kidney international, 2022 Oct;102(4):930-9352022
Shafi T, Zhu X, Lirette ST, Rule AD, Mosley T, Butler KR, Hall ME, Vaitla P, Wynn JJ, Tio MC, Dossabhoy NR, Guallar E, Butler J, Quantifying Individual-Level Inaccuracy in Glomerular Filtration Rate Estimation : A Cross-Sectional Study. Annals of internal medicine, 2022 Aug;175(8):1073-10822022
Liu J, Tio MC, Verma A, Schmidt IM, Ilori TO, Knauf F, Mc Causland FR, Waikar SS, Determinants and Outcomes Associated With Urinary Calcium Excretion in Chronic Kidney Disease. The Journal of clinical endocrinology and metabolism, 2022 Jan 1;107(1):e281-e2922022
Gupta S, Short SAP, Sise ME, Prosek JM, Madhavan SM, Soler MJ, Ostermann M, Herrmann SM, Abudayyeh A, Anand S, Glezerman I, Motwani SS, Murakami N, Wanchoo R, Ortiz-Melo DI, Rashidi A, Sprangers B, Aggarwal V, Malik AB, Loew S, Carlos CA, Chang WT, Beckerman P, Mithani Z, Shah CV, Renaghan AD, Seigneux S, Campedel L, Kitchlu A, Shin DS, Rangarajan S, Deshpande P, Coppock G, Eijgelsheim M, Seethapathy H, Lee MD, Strohbehn IA, Owen DH, Husain M, Garcia-Carro C, Bermejo S, Lumlertgul N, Seylanova N, Flanders L, Isik B, Mamlouk O, Lin JS, Garcia P, Kaghazchi A, Khanin Y, Kansal SK, Wauters E, Chandra S, Schmidt-Ott KM, Hsu RK, Tio MC, Sarvode Mothi S, Singh H, Schrag D, Jhaveri KD, Reynolds KL, Cortazar FB, Leaf DE, ICPi-AKI Consortium Investigators, Acute kidney injury in patients treated with immune checkpoint inhibitors. Journal for immunotherapy of cancer, 2021 Oct;9(10)2021
Pfau A, Ermer T, Coca SG, Tio MC, Genser B, Reichel M, Finkelstein FO, März W, Wanner C, Waikar SS, Eckardt KU, Aronson PS, Drechsler C, Knauf F, High Oxalate Concentrations Correlate with Increased Risk for Sudden Cardiac Death in Dialysis Patients. Journal of the American Society of Nephrology : JASN, 2021 Sep;32(9):2375-23852021
Tio MC, Sparks MA, Neyra JA, The International Biomedical Workforce is Critical to Our Response to COVID-19 in the United States. Mayo Clinic proceedings, 2020 Nov;95(11):2336-23382020
Neyra JA, Tio MC, Ferrè S, International Medical Graduates in Nephrology: A Guide for Trainees and Programs. Advances in chronic kidney disease, 2020 Jul;27(4):297-304.e12020
Gupta S, Tio MC, Gutowski ED, Stecker MS, Verma A, Motwani SS, Mount DB, McMahon GM, Waikar SS, Incidence of Hyponatremia in Patients With Indwelling Peritoneal Catheters for Drainage of Malignant Ascites. JAMA network open, 2020 Oct 1;3(10):e20178592020
Verma A, Patel AB, Tio MC, Waikar SS, Caring for Dialysis Patients in a Time of COVID-19. Kidney medicine, 2020 Oct 14;2(6):787-922020
Bargagli M, Tio MC, Waikar SS, Ferraro PM, Dietary Oxalate Intake and Kidney Outcomes. Nutrients, 2020 Sep 2;12(9)2020
Li P, Schmidt IM, Sabbisetti V, Tio MC, Opotowsky AR, Waikar SS, Plasma Endothelin-1 and Risk of Death and Hospitalization in Patients Undergoing Maintenance Hemodialysis. Clinical journal of the American Society of Nephrology : CJASN, 2020 Jun 8;15(6):784-7932020
Gutowski ED, Tio MC, Burch EA, Leaf DE, Peritoneal dialysate tamponading a massive retroperitoneal hemorrhage. Kidney international, 2020 Apr;97(4):8102020
Li GZ, Tio MC, Pak LM, Krier J, Seifter JL, Tullius SG, Riella LV, Malek SK, Stergachis AB, Noncirrhotic hyperammonemia after deceased donor kidney transplantation: A case report. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2019 Nov;19(11):3197-32012019
Gregg LP, Tio MC, Li X, Adams-Huet B, de Lemos JA, Hedayati SS, Association of Monocyte Chemoattractant Protein-1 with Death and Atherosclerotic Events in Chronic Kidney Disease. American journal of nephrology, 2018;47(6):395-405

Book Chapter

Tio MC, McMahon GM Rhabdomyolysis Handbook of Critical Care Nephrology

Editorial

Tio MC, Shafi T, The Limits of Generalizability: Pitfalls of Applying Western GFR Estimation Models to Global Populations. Kidney international reports, 2024 Dec;9(12):3355-33572024

Presentations

State/Local Invited Seminars/Lectures, Department of Internal Medicine Grand Rounds ACP Debate: Medicine, A Job or a Calling?, Department of Medicine, Jackson, MS05/2025
Regional Invited Seminars/Lectures, Clinical Educator Career Advancement Workshop: Identifying Mentors, Southern Regional Meeting/Southern Society for Clinical Investigation, New Orleans, LA02/2025
Invited Podcast, Early uACR and eGFR Testing to Improve Clinical Outcomes, American Heart Association, https://professional.heart.org/en/education/the-link-between-ckd-and-cvd#podcast10/2024
Poster Presentation, GFR Estimation Errors and Association with Outcomes in CKD, American Society of Nephrology, Kidney Week, American Society of Nephrology, Kidney Week, San Diego, CA10/2024
Invited Podcast, Individualized Risk of CKD Progression Among US Adults, Journal of the American Society of Nephrology Podcast, https://www.asn-online.org/media/podcast.aspx?ID=51906/2024
State/Local Invited Seminars/Lectures, UMMC Department of Internal Medicine Grand Rounds: Chronic Kidney Disease: A 2024 Update, UMMC Department of Medicine, Jackson, MS03/2024
Regional Invited Seminars/Lectures, The Cardiovascular Health of US Adults with Chronic Kidney Disease, Southern Regional Meeting/Southern Society for Clinical Investigation, New Orleans, LA02/2024
Regional Invited Seminars/Lectures, Managing Time: The Long and the Short, Southern Regional Meeting/Southern Society for Clinical Investigation, New Orleans, LA02/2024
National and International Invited Seminars/Lectures, Cardiorenal Session: Decongestion and GDMT Optimization in HF and CKD, American Heart Association, Philadelphia, PA11/2023
Poster Presentation, Validation of a Multimarker eGFR Equation In Preserved and Reduced eGFR Using the GENOA Cohort, American Society of Nephrology, Kidney Week, Philadelphia, PA11/2023
National and International Invited Seminars/Lectures, External Validation of a Novel Multimarker GFR Estimating Equation, European Renal Association Congress, Milan, Italy06/2023
National and International Invited Seminars/Lectures, Assessing the 3-Year Risk of 40% eGFR Decline or Kidney Failure in the US Population, European Renal Association Congress, Milan, Italy06/2023
Regional Invited Seminars/Lectures, Quantification of Risk of Chronic Kidney Disease Progression in the US Population, Southern Regional Meeting/Southern Society for Clinical Investigation, New Orleans, LA02/2023
National and International Invited Seminars/Lectures, Intersection of Kidney and Heart Failure- Biomarkers, Treatment, and Outcomes in Patients with Cardiorenal Disease, American Heart Association Scientific Sessions, Chicago, IL11/2022
Poster Presentation, 5-Year Risk of End Stage Kidney Disease in the US Population: Implications for Kidney Care Referral, American Society of Nephrology, Kidney Week, Orlando, Fl11/2022
National and International Invited Seminars/Lectures, Changes in CKD Prevalence in the US Using the Age-Adapted CKD Classification System, American Society of Nephrology Kidney Week, Orlando, FL11/2022
Poster Presentation, Changes in CKD Prevalence with and Without eGFR Indexing to the Median Body Surface Area in the US, American Society of Nephrology, Kidney Week, Orlando, Fl11/2022
Regional Invited Seminars/Lectures, A Comparison Of Trends In Chronic Kidney Disease In Mississippi Using The Chronic Kidney Disease Epidemiology Collaboration 2009 Vs. 2021 Equations, Southern Regional Meeting/Southern Society for Clinical Investigation, New Orleans, LA02/2022
Regional Invited Seminars/Lectures, A Comparison Of Trends In Chronic Kidney Disease In Mississippi Using The Chronic Kidney Disease Epidemiology Collaboration 2009 Vs. 2021 Equations, Southern Regional Meeting/Southern Society for Clinical Investigation, New Orleans, LA02/2022
Regional Invited Seminars/Lectures, Associations of plasma oxalate in CKD progression and death using the Chronic Renal Insufficiency Cohort, Women in Nephrology, Virtual and In-Person (Birmingham, AL)09/2021
National and International Invited Seminars/Lectures, Monocyte Chemoattractant Protein-1 (MCP-1) is Associated with Atherosclerotic (ASCV) Events and Death in CKD, American Society of Nephrology Kidney Week, New Orleans, LA11/2017

Honors, Awards, and Recognition

Tinsley Harrison Scholar, Southern Society for Clinical Investigation2025

Professional Membership and Service

Southern Society for Clinical Investigation, Fellow2025 - Present
Southern Society for Clinical Investigation, Officer, Other Officer2025 - Present
American Kidney Fund, Unknown Causes of Chronic Kidney Disease Healthcare Professionals Working Group2024 - Present
Southern Society for Clinical Investigation, Member2021 - Present
American Society of Nephrology, Fellow2021 - Present
American Kidney Fund, Clinical Scientist in Nephrology Fellow2020 - 2021
American Society of Nephrology, Member2016 - Present

Committee Service

Nephrology- Program Evaluation Committee, Member2025 - Present
Medicine- House Officer Selection Committee, Member2024 - Present
Nephrology- Clinical Competency Committee, Chair2024 - Present
Nephrology- Clinical Competency Committee, Member2022 - Present

Community Service

Kidney Action Week, American Kidney Fund, Moderator03/2024 - 03/2024
Kidney Health Coach Collaborative Speaker, American Kidney Fund, Guest Speaker04/2023 - 04/2023
Carolyn Wilson Patient Scholarship Selection Committee, American Kidney Fund, Member04/2022 - 08/2022
Webinar: “Kidney Chat- Ask a Nephrologist about COVID-19", American Kidney Fund, Guest Speaker04/2020 - 04/2020

Other Service

International Medical Graduates Interest Group (Department of Medicine), Organizer07/2023 - Present
Invited reviewer for manuscripts from journals including: Clinical Journal of the American Society of Nephrology, Kidney360, Kidney Medicine, Journal of the American Heart Association, American Journal of Kidney Disease, Biology of Sex Differences11/2021 - Present

Teaching Experience

SOM 615, Medicine, Lecture, Lecturer, Polycystic Kidney DiseaseSpring 2024 - 2024
CONJ 612, Medicine, Lecture, Lecturer, Ethics of Dialysis Panel DiscussionSpring 2024 - 2024
Medicine, Lecture, Lecturer, Nephrology Board Review SeriesAnnual 2023
Medicine, Lecture, Lecturer, Continuous Renal Replacement TherapySpring 2023 - 2023
Medicine, Small Group, Facilitator, Medical Physiology Kidney PBLSpring 2022-2023 - 2023
Medicine, Lecture, Lecturer, Internal Medicine Board Review- NephrologyAnnual 2022
Medicine, Lecture, Lecturer, Acute Kidney InjuryAnnual 2022 - 2023
Medicine, Lecture, Lecturer, Step 1 Review Series: Renal/UrinarySpring 2021-2022 - 2022
Medicine, Lecture, Lecturer, Kidney Complications in Acute Liver FailureAnnual 2021

Directed Student Learning

Supervised Research, Advised: Wesley Zhang2022 - 2023

Fellows supervised

Nephrology Fellowship Program, Assistant Fellowship Director, 15 fellows supervised07/2024 - Present

Residency Training

Division of Nephrology Fellowship Program, Assoc. Program Director2024 - Present