Larry S. Mcdaniel, PhD

Larry S. Mcdaniel, PhD

Professor

Department:
SOM-Cell and Molecular Biology

Email:
lmcdaniel@umc.edu

Work Phone:
(601) 984-1701

Education

University of Oklahoma, PhD, Microbiology1981
University of Southwestern Louisiana, MS, Microbiology1978
Southeastern Louisiana University, BS, Microbiology1974
University of Alabama at Birmingham, NIH Fellowship: Microbial Pathogenesis and Immunology

Current Positions

Department Chair2017 - Present
Professor, School of Medicine, Department of Microbiology2001 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Interim-Chair, University of Mississippi Medical Center2016 - 2017
Vice Chair, University of Mississippi Medical Center Department of of Microbiology and Immunology2015 - 2016
Adjunct Associate Professor, University of Alabama at Birmingham, School of , Department of Microbiology1995 - 2001
Associate Professor, University of Mississippi Medical Center, Jackson, MS, School of Medicine, Department of Microbiology1995 - 2001
Assistant Professor, University of Alabama at Birmingham, Department of Microbiology1989 - 1995
Instructor, Univeristy of Alabama at Birmingham, School of , Department of Microbiology1987 - 1989
Research Associate, Univeristy of Alabama, Department of Microbiology1985 - 1987
Quality Control Supervisor1974 - 1976
Media Prep Lab Technician, Southeastern Louisiana University1972 - 1974
Quality Control Microbiologist

Sponsored Program Funding

Intramural, Bacterial evasion of innate immunity, Intramural Research Support Program UMC11/2006 - 10/2007

Publications

US Patent #6,592,876

Larry S. McDaniel Pneumococcal genes, portions thereof, expression products there from, and uses of such genes, portions and products2003

US Patent #6,500,613

Larry S. McDaniel Pneumococcal surface proteins and uses thereof2002

US Patent #5,997,882

Larry S. McDaniel Epitopic regions of pneumococcal surface protein A1999

US Patent #6,004,802

Larry S. McDaniel Oral administration of pneumococcal antigens1999

US Patent #5,476,929

Larry S. McDaniel Structural gene of pneumococcal protein1995

Journal Article

Moore III, Q.C., McCormick, C.C., Norcross, E.W., Onwubiko, C., Sanders, M.E., Fratkin, J., McDaniel, L.S., O’Callaghan, R.J., and Marquart, M.E. Development of a Streptococcus pneumoniae keratitis model in mice. Ophthalmic Res. 2010, 42:141-1462010
King, L., Swiatlo, E., Swiatlo, A., and McDaniel, L.S. Serum resistance and biofilm formation in clinical isolates of Acinetobacter baumannii. FEMS Immunol. Med. Microbio. 55:414-421. 2009.2009
Onwubiko, C., Swiatlo, E., and McDaniel, L.S. Cross-sectional study of nasopharyngeal carriage of Streptococcus pneumoniae in human immunodeficiency virus-infected adults in the conjugate vaccine era J. Clin. Microbiol. 46:3621-3625. 2008.2008
Quin LR, Moore QC, Thornton JA, McDaniel LS Peritoneal challenge modulates pneumococcal expression of PspC during bacteremia in mice Infect. Immun. 2008; 76:1122-11272008
Green SN, Sanders M, Moore III QC, Norcross EW, Mounds KS, Caballero AR, McDaniel LS, Robinson SA, Onwubiko C, O’Callaghan RJ, Marquart ME Protection from Streptococcus pneumoniae keratitis by passive immunization with pneumolysin antiserum Invest. Ophthalmol. Vis. Sci. 2008; 49:290-2942008
Onwubiko, C., Shires, C., Quin, L.R., Swiatlo, E., and McDaniel, L.S. Characterization of Streptococcus pneumoniae isolated from children with otitis media FEMS Immunol. Med. Microbiol. 50:119-125. 20072007
Marquart, M.E., Monds, K.S., McCormick, C.C., Dixon, S.N., Sanders, M.E., Reed, J.M., McDaniel, L.S., Caballero, A.R., and O’Callaghan, R.J. Cholesterol as treatment for pneumococcal keratitis: cholesterol-specific inhibition of pneumolysin in the cornea Invest. Ophthalmol. Vis. Sci. 48:2661-2666. 20072007
Rogers PD, Liu, TT, Barker, KS, Hilliard, GM, English, BK, Thornton, J, Swiatlo, E, and McDaniel, LS Gene expression profiling of the response of Streptococcus pneumoniae to penicillin. J Antimicrob Chemother. 59:616-626. 2007.2007
Moore, Q.C., Johnson, L., Repka, M., and McDaniel, L.S. Immunization with PspA Incorporated into a Poly(Ethylene Oxide) Matrix Elicits Protective Immunity against Streptococcus pneumoniae Clin. Vaccin. Immunol. 14:789-791. 2007.2007
Mills MF, Marquart ME, and McDaniel LS. Localization of PcsB of Streptococcus pneumoniae and its differential expression in response to stress. J Bacteriol. 189:4544-45446. 2007.2007
Quin, L.R., Moore, Q.C., and McDaniel, L.S. Pneumolysin, PspA, and PspC contribute to pneumococcal evasion of early innate immune responses during bacteremia in mice Infect. Immun. 2007 75:2067-20702007
He, X., and McDaniel, L.S. The genetic background of Streptococcus pneumoniae affects the protection of mice immunized with PspA FEMS Microbiol. Lett. 269:189-195, 20072007
Quin LR, Onwubiko C, Moore QC, Mills MF, McDaniel LS, Carmicle S Factor H binding to PspC of Streptococcus pneumoniae increases adherence to human cell lines in vitro and enhances invasion of mouse lungs in vivo Infect. Immun. 2007; 75:4082-40872007
Moore, Q.C., Bosarge, J.R., Quin, L.R., and McDaniel, L.S. Enhanced protective immunity against pneumococcal infection with PspA DNA and protein Vaccine 24:5755-5761, 20062006
Quin, L.R., Onwubiko, C., Carmicle, S., and McDaniel, L.S. Interaction of clinical isolates of Streptococcus pneumoniae with human complement factor H. FEMS Microbiol. Lett. 264:98-103, 20062006
He, X., Thornton, J., Carmicle-Davis, S., and McDaniel, L.S. Tex, a Putative Transcriptional Accessory Factor, Is Involved in Pathogen Fitness in Streptococcus pneumoniae Microbial Pathogen. 41:199-206, 20062006
Hu, L., Guo, M., He, Z., Thornton, J., McDaniel, L.S., and Hughson, M.D. Human papillomavirus genotyping and p16(INK4a) expression in cervical intraepithelial neoplasia of adolescents Mod. Pathol. 18:267-273, 20052005
Quin, L.R., Carmicle, S., Dave, S., Pangburn, M.K., Evenhuis, J.P., and McDaniel, L.S. In Vivo Binding of Complement Regulator Factor H by Streptococcus pneumoniae J. Infect. Dis. 192:1996-2003, 2005.2005
Thornton, J., and McDaniel, L.S. THP-1 monocytes up-regulate intercellular adhesion molecule 1 in response to pneumolysin from Streptococcus pneumoniae Infect. Immun. 73:6493-6498, 20052005
Dave, S., Carmicle, S., Hammerschmidt, S. Pangburn, M.K., and McDaniel, L.S. Dual roles of PspC, a surface protein of Streptococcus pneumoniae, in binding human sIgA and Factor H J. Immunol. 173:471-477, 20042004
Dave, S., Pangburn, M.K., Pruitt, C., and McDaniel, L.S. Interaction of human factor H with PspC of Streptococcus pneumoniae Indian J. Med. Res. 199(suppl.):66-73, 20042004
McDaniel, L.S., and Swiatlo, E. Pneumococcal disease: Pathogenesis, treatment, and prevention Infect. Dis. Clin. Pract. 12:93-98, 20042004
McDaniel, L.S., Thronton, J., and McDaniel, D.O. Use of cDNA microarrays to analyze pneumococcal virulence factors Indian J. Med. Res. 199(suppl.):99-103, 20042004
McDaniel, D.O., Barber, W.H., Nguyan, C., Rhodes, S.W., May,W.L., McDaniel, L.S., Vig, P.J.S., Jemeson, L.L., and Butkus, D.E. Combined analysis of cytokine genotype polymorphism and the level of expression with allograft function in African-American renal transplant patients Transpl. Immunol. 11:107-119, 20032003
Rogers, P.D., Thornton, J., Barker, K.S., McDaniel, D.O., Sacks, G.S., Swiatlo, E., and McDaniel, L.S. Pneumolysin-dependent and –independent gene expression identified by cDNA microarray analysis of THP-1 human mononuclear cells stimulated by Streptococcus pneumoniae Infect. Immun. 71:2087-2094, 20032003
Roche, H., Ren, B., McDaniel, L.S., Hakansson, A., and Briles, D.E. Relative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae Infect. Immun. 71:4498-4505, 20032003
Anders, H., Roche, H., Mirza, S., McDaniel, L.S., Brooks-Walter, A., and Briles, D.E. Characterization of binding of human lactoferrin to pneumococcal surface protein A Infect. Immun. 69:3372-3381, 20012001
Bosarge,J., Watt, J.M., McDaniel, D.O., Swiatlo, E., and McDaniel, L.S. Genetic immunization with the region encoding the -helical domain of PspA elicits protective immunity against Streptococcus pneumoniae Infect. Immun. 69:5456-5463, 20012001
Dave, S., Brooks-Walter, A., Pangburn, M.K., and McDaniel, L.S. PspC, a Pneumococcal Surface Protein, Binds Human Factor H Infect. Immun. 69:3435-3437, 20012001
McDaniel, D.O., Nguyen, C., and McDaniel, L.S. A new HLA-DPA1 allele, DPA1*02016, identified in African-American population Tissue Antig. 56:197-198, 20002000
Swiatlo, E., Moore, E., Watt, J., and McDaniel, L.S. Invitro activity of four fluoroquinolones against clinical isolates of Pseudomonas aeruginosa determined by the E test Int. J. Antimicrob. Agents. 15: 73-76, 20002000
Nayak, A.R., Tinge, S.A., Tart, R.C., McDaniel, L.S., Briles, D.E., and Curtiss,III, R. A live recombinant avirulent oral Salmonella vaccine expressing pneumococcal surface protein A (PspA) induced protective responses against Streptococcus pneumoniae Infect. Immun. 66: 3744-3751, 19981998
McDaniel, L.S., McDaniel, D.O., Hollingshead, S.K., and Briles, D.E. Comparison of the PspA sequence from Streptococcus pneumoniae EF5668 to the previously identified PspA sequence from strain Rx1 and ability of PspA from EF5668 to elicit protection against pneumococci of different capsular types Infect. Immun. 66:4748-4754, 19981998
Wortham, C., Grinberg, L., Kaslow, D.C., Briles, D.E., McDaniel, L.S., Lees, A., Flora, M., Snapper, C.M., and Mond, J.J. Enhanced protective antibody responses to PspA after intranasal or subcutaneous injections of PspA genetically fused to granulocyte-macrophage colony-stimulating factor or interleukin-2 Infect. Immun. 66:1513-1520, 19981998
McDaniel, L.S., Loechel, F., Benedict, C., Greenway, T., Briles, D.E., Conry, R.M., and Curiel, D.T. Immunization with a plasmid expressing pneumococcal surface protein A (PspA) can elicit protection against fatal infection with Streptococcus pneumoniae. Gene Therapy. 4:375-377, 19971997
Swiatlo, E., Brooks-Walter, A., Briles, D.E., and McDaniel, L.S. Oligonucleotides identify conserved and variable regions of pspA and pspA-like sequences of Streptococcus pneumoniae Gene. 188:279-284, 19971997
Yamamoto, M., McDaniel, L.S., Kawabata, K., Briles, D.E., Jackson, R.J., McGhee, J.R., and Kiyono, H. Oral immunizationwith PspA elicits protective humoral immunity against Streptococcus pneumoniae infection Infect. Immun. 65:640-644, 19971997
Swiatlo, E., Crain, M.J., McDaniel, L.S., Brooks-Walter, A., Coffey, T. J., Spratt, B.G., Morrison, D.A., and Briles, D.E. DNA polymorphisms and variant penicillin-binding proteins as evidence that relatively penicillin-resistant pneumococci in western Canada are clonally related J. Infect. Dis. 174:884-888, 19961996
Crain, M.J., Turner, J.S., Robinson, D.A., Coffey, T.J., Brooks-Walter, A., McDaniel, L.S., and Briles, D.E. Evidence for the simultaneous expression of two PspAs by a clone of capsular serotype 6B Streptococcus pneumoniae Microbio. Path. 21:265-275, 19961996
Briles, D.E., King, J.D., Gray, M.A., McDaniel, L.S., Swiatlo, E., and Benton, K.A. PspA, a protection-eliciting pneumococcal protein: immunogenicity of isolated native PspA in mice Vaccine. 14:858-867, 19961996
Tart, R.C., McDaniel, L.S., Ralph, B.A., and Briles, D.E. Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice J. Infect. Dis. 173:380-386, 19961996
Ralph, B.A., Briles, D.E., and McDaniel, L.S. Cross-reactive protection eliciting epitopes of pneumococcal surface protein A Annals New York Acad. Sci. 1994, 730:361-3631994
McDaniel, L.S., Ralph, B. A., McDaniel, D. O., and Briles, D. E. Localization of protection eliciting epitopes on PspA of Streptococcus pneumoniae between amino acid residues 192 and 260 Microbial Pathogenesis. 17:323-337, 19941994
Talkington, D. F., Voellinger, D. C., McDaniel, L. S. and Briles, D. E. Analysis of pneumococcal PspA microheterogeneity in SDS polyacrylamide gels and the association of PspA with the cell membrane Microbial Pathogenesis. 13:343-355, 19921992
Sheffield, J.S., Benjamin, Jr., W.H., and McDaniel, L.S. Detection of DNA in southern blots by chemiluminescence is a sensitive and rapid technique Biotechniques 12:836-839, 19921992
McDaniel, L.S., Sheffield, J.S., Swiatlo, E., Yother, J., Crain, M.J., and Briles, D.E. Molecular localization of variable and conserved regions of pspA and identification of additional pspA homologous sequences in Streptococcus pneumoniae Microbial Pathogenesis 13:261-269, 19921992
McDaniel, L.S., Steinbronn, J.L.,Bowen, P. and Briles, D. E. PspA, a Surface Protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular type Infect. and Immun. 59: 222-228. 19911991
Crain, M. J., Waltman, W. D., II, Turner, J. S., Yother, J., Talkington, D. F., McDaniel, L. S., Gray, B. M., and Briles, D. E. Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae Infect. and Immun. 58: 3293-3299, 19901990
Waltman, W. D., II, McDaniel, L. S., Gray, B. M. and Briles, D. E. Variation in the molecular weight of PspA (pneumococcal surface protein A) in Streptococcus pneumoniae Microbial Pathogenesis. 8:61-69, 19901990
Briles, D.E., Forman, C., Horowitz, J.C., Volanakis, J.E., Benjamin, W.H. Jr., McDaniel, L.S., Eldridge, J., and Brooks, J. Antipneumococcal effects of C-reactive protein and monoclonal antibodies to pneumococcal cell wall and capsular antigens Infect. Immun. 57:1457-1464. 19891989
McDaniel, L. S. and Briles, D. E. A pneumococcal surface protein (PspB) that exhibits the same protease sensitivity as streptococcal R antigen. Infect. Immun. 56:3001-3003, 1988.1988
Waltman, W. D., II, Gray, B. M., McDaniel, L. S. and Briles, D. E. Cross-reactive monoclonal antibodies in the diagnosis of pneumococcal meningitis. J. Clin. Microbial. 26:1625-1640, 1988.1988
Watson, H. L., McDaniel, L. S., Blalock, D. K., Fallon, M. T. and Cassell, G. H. Heterogeneity among strains and a high rate of variation within strains of a major surface antigen of Mycoplasma pulmonis. Infect. Immun. 56:1358-1363, 1988.1988
Waltman, W. D., II, McDaniel, L. S., Andersson, B., Bland, L., Gray, B. M., Svanborg-Eden, C. and Briles, D. E. Protein serotyping of Streptococcus pneumoniae based on reactivity to six monoclonal antibodies Microbial Pathogenesis. 5:159-167, 1988.1988
McDaniel, L. S., Waltman, W. D., II, Gray, B. and Briles, D. E. A protective monoclonal antibody that reacts with a novel antigen of pneumococcal teichoic acid Microbial Pathogenesis. 3:249-260, 19871987
McDaniel, L. S., Yother, J. Vijakumar, M., McGarry, L., Guild, W. R. and Briles, D. E. Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA) J. Exp. Med. 165:381-394, 19871987
McDaniel, L. S., Scott, G., Carrol, J. M. and Briles, D. E. Analysis of a surface protein of Streptococcus pneumoniae recognized by protective monoclonal antibodies Microbial Pathogenesis. 1:519-531, 19861986
Yother, J., McDaniel, L. S. and Briles, D. E. Transformation of encapsulated Streptococcus pneumoniae J. Bacteriol. 168:1463-1465, 19861986
McDaniel, L. S., Benjamin, W. H., Forman, C. and Briles, D. E. Blood clearance by anti-phosphocholine antibodies as a mechanism of protection in experimental pneumococcal bacteremia J. Immunol. 1984, 133:3308-33121984
McDaniel, L. S., Scott, G. Kearney, J. F. and Briles, D. E. Monoclonal antibodies against protease sensitive pneumococcal antigens can protect mice from fatal infection with Streptococcus pneumoniae J. Exp. Med. 160:386-397, 19841984
McDaniel, L. S. and Cozad, G. C. Immunomodulation by Blastomyces dermatitidis; functional activity of murine peritoneal macrophages Infect. Immun. 40:733-740, 19831983
McDaniel, L. S. and Cozad, G. C. Immunoadjuvant effects Blastomyces dermatitidis against EL4 lymphoma in C57BL/6J mice J. Natl. Cancer Inst. 69:1337-1342, 19821982
McDaniel, L. S., Rogers, L. H. and Hill, W. E. Survival of recombination-deficient mutants of Escherichia coli during incubation with nalidixic acid J. Bacteriol. 134:1195-1198, 19781978

Review Article

Swiatlo, E., McDaniel, L.S., and Briles, D.E. Choline-binding proteins In: E. Tuomanen, T.J. Mitchell, D.A. Morrison, and B.G. Spratt eds. The Pneumococcus. American Soc. Microbiol. Press, Washington, DC., p.49-60, 20042004
McDaniel, L.S., and Bosarge, J.R. Cellular transport of DNA as a vehicle for genetic implants J. Long Term Effects Medical Implants. 12:63-70, 20022002
Briles, D.E., Tart, R.C., Swiatlo, E., Dillard, J.P., Smith, P., Beton, K.A., Ralph, B.A., Brooks-Walter, A., Crain, M.J., Hollingshead, S.K., and McDaniel, L.S. Pneumococccal diversity: consideration for new vaccine strategies with an emphasis on pneumococcal surface protein A (PspA) Clin. Microbiol. Rev. 11:645-657, 19981998
Briles, D.E., Tart, R.C., Wu, H.Y., Ralph, B.A., Russell, M.W., and McDaniel, L.S. Systemic and mucosal protective immunity to pneumococcal surface protein A Annals New York Academy of Sciences. 797:118-126, 19961996
McDaniel, L.S., and McDaniel, D.O. Analysis of the gene encoding type 12 PspA of Streptococcus pneumoniae EF5668 In: J.J. Ferretti, M.S. Gilmore, T.R. Klaenhammer, and F. Brown eds., Genetics of Streptococci, Enterococci, and Lactococci. Proceedings of the IV ASM International Conference on Streptococcal Genetics. Developments in Biological Standardiztion. Karger, New York, vol. 85:283-286, 19951995
Yother, J., McDaniel, L. S., Crain, M. J., Talkington, D. K., Briles, D. E. Pneumococcal surface protein A: Structural analysis and biological significance In: G. M. Dunny, P. P. Cleary, and L. L. Mckay, eds., Genetics and molecular biology of streptococci, lactococci, and enterococci. American Society for Microbiology, Washington, DC. pp. 88-91, 19911991
Briles, D. E., Yother, J. and McDaniel, L. S. Role of pneumococcal surface protein A in the virulence of Streptococcus pneumoniae Rev. Inf. Dis. l0:S372-S374, 19881988
McDaniel, L. S., Yother, J., Waltman, W. D., II and Briles, D. E. Studies on PspA (pneumococcal surface protein A) insertionally inactivated mutants In: J. J. Ferretti and R. Curtiss, III, ed., Streptococcal Genetics. American. Soc. Microbiol., Washington, D.C., p. 172-176, 19871987
McDaniel, L. S., and Briles, D. E. Monoclonal antibodies against surface components of Streptococcus pneumoniae In: A. J. L. Macario and E. C. de Macario, ed., Monoclonal antibodies against bacteria, Vol.3. Academic Press, Orlando, FL., p. 143-164, 19861986

Abstracts

Kiing, L.B., and McDaniel, L.S. A serine protease is involved in Acinetobacter baumannii serum resistance Am. Soc. Microbiol. General Meeting, May, 20102010
King, L.B., Nanduri, B., Burgess, S., and McDaniel, L.S.: Acinetobacter baumannii protease is involved in serum resistance Am. Soc. Microbiol. General Meeting, May, 20092009
Mills, M.F., Burton, R.L., Nahm, M.H., Briles, D.E., Moore, III, Q.C., and McDaniel, L.S. Intranasal Immunization with PcsB of Streptococcus pneumoniae Reduces Nasopharyngeal Colonization in Mice Am. Soc. Microbiol. General Meeting, May, 20092009
King LB, Swiatlo E, McDaniel LS Serum-Sensitivity of Acinetobacter baumannii Am. Soc. Microbiol. General Meeting2008
Onwubiko, C., Shires, C., Quin, L.R., Swiatlo, E., and McDaniel, L.S. Characterization of pediatric pneumococcal otitis media isolates J. Mississippi Academy of Sciences 2007, 52:952007
Moore, Q., Johnson, L., Repka, M., and McDaniel, L.S. Immunization with PspA incorporated into a poly(ethylene oxide) matrix elicits protective immunity against Streptococcus pneumoniae J. Mississippi Academy of Sciences 2007, 52:1092007
Sanders, M., Dixon, S.N., McDaniel, L.S., and Marquart, M.E. Neutralization of Streptococcus pneumoniae pneumolysin by anti-pneumolysin immunoglobulin G J. Mississippi Academy of Sciences 2007, 52:952007
Sanders, M., Dixon, S.N., McDaniel, L.S., and Marquart, M.E.: Neutralization of Streptococcus pneumoniae pneumolysin by anti-pneumolysin immunoglobulin G J. Mississippi Academy of Sciences 52:95, 20072007
McDaniel LS, Quin LR, Onwubiko C, Mills MF Factor H binding to PspC of Streptococcus pneumoniae increases adherence to human cell lines in vitro and enhances invasion of mouse lungs in vivo Infect. Dis. Soc. Am., Annual Meeting2007
Onwubiko C, Swiatlo E, McDaniel LS Nasopharyngeal carriage of Streptococcus pneumoniae in HIV-infected patients in the conjugate vaccine era Infect. Dis. Soc. Am., Annual Meeting2007
Onwubiko, C., Mills, M.F., Pfluger, V., Pluschke, G., and McDaniel, L.S. Characterization of non-hemolytic pneumolysin from invasive Streptococcus pneumoniae isolates Am. Soc. Microbiol. General Meeting, May, 2007.2007
Mills, M.F., Thornton, J., and McDaniel, L.S. Pneumolysin release is linked to serotype 3 capsule in Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, May, 2007.2007
Onwubiko, C., Quin, L.R., Carmicle, S., and McDaniel, L.S. Analysis of human complement factor H binding to Streptococcus pneumoniae clinical isolates J. Mississippi Academy of Sciences 51:67-68, 20062006
Shires, C., Quin, L.R., and McDaniel, L.S. Analysis of Streptococcus pneumoniae from middle ear effusions of children in Mississippi using PspA family typing and box PCR based DNA finger printing. J. Mississippi Academy of Sciences 51:68, 20062006
Mills, M.F., Marquart, M.E., and McDaniel, L.S. Antibodies to PcsB of Streptococcus pneumoniae fail to protect against lethal pneumococcal challenge Am. Soc. Microbiol. General Meeting, May, 20062006
Onwubiko, C., Thornton, J., and McDaniel, L.S. Effects of pneumolysin on intracellular adhesioni molecule-1 expression in endothelial cells Am. Soc. Microbiol. General Meeting, May, 20062006
Quin, L.R., Moore, Q.C., Carmicle, S., and McDaniel, L.S.: The combined role of pneumolysin, PspA, and PspC in complement deposition and virulence of Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, May, 20062006
He, X., Thornton, J., and McDaniel, L.S. A pneumococcal homologue of tex is not an essential gene The Lancefield Society Meeting, 20052005
McDaniel, D.O., Zhou, X., Tee, L.Y., McDaniel, L.S., Calicote, L., and Barber, W.H. Impact of peripheral blood IL-18 gene early expression on kidney allograft long-term outcome Human Immunol. 66:S542005
Carmicle, S., Quin, L.R., and McDaniel, L.S. Interaction of PspC with human complement inhibitory protein factor H The Lancefield Society Meeting, 20052005
Thornton, J., Homayouni, R., Hooshdaran, M.Z., English, B.K., Swiatlo, E., McDaniel, L.S., and Rogers, P.D. Modulation of the Streptococcus pneumoniae-induced gene expression profile of THP-1 human monocytic cells by sub-inhibitory concentrations of penicillin and clarithromycin 45th ICAAC Abstracts p. 43, 20052005
Thornton, J., and McDaniel, L.S. Pneumolysin-dependent up-regulation of ICAM-1 in THP-1 monocytes exposed to Streptococcus pneumoniae 45th ICAAC Abstracts p. 44, 20052005
Hooshdaran, M.Z., Liu, T.T., Barker, K.S., Hilliard, G.M., English, B.K., Thornton, J., Swiatlo, E., McDaniel, L.S., and Rogers, P.D. Transcriptional modulation of gene expression in Streptococcus pneumoniae in response to subinhibitory concentrations of penicillin and clarithromycin 45th ICAAC Abstracts p. 71, 20052005
Carmicle, S., and McDaniel, L.S.: The interaction of pneumococcal surface protein C and factor H in pneumococcal isolates from infective endocarditis Am. Soc. Microbiol. General Meeting, June, 20052005
Quin, L.R., Onwibuko, C., Carmicle, S., and McDaniel, L.S. Binding of factor H to clinical isolates of Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, June, 20052005
Moore, III, Q.C., and McDaniel, L.S. Protection against pneumococcal disease by prime-boost immunization with pspA/EF5668 Am. Soc. Microbiol. General Meeting, June, 20052005
McDaniel, L.S., Quin, L.R., Onwubiko, C., Hammerschmidt, S., and Carmicle, S. PspC increases pneumococcal virulence by recruitment of complement factor H 7th European Meeting on the Molecular Biology of Pneumococcus, Braunschweig, Germany, May, 20052005
Moore, III, Q.C., and McDaniel, L.S.: Protection against Streptococcus pneumoniae by prime-boost immunization with pspA/EF5668 St. Jude Children Research Hospital National Graduate Student Symposium. April, 2005.2005
He, X., Thornton, J.A., and McDaniel, L.S. A pneumococcal protein involved in low temperature growth Am. Soc. Microbiol. General Meeting, 20042004
Onwubiko, C., Quin, L.R., Carmicle, S., and McDaniel, L.S. Binding of factor H to clinical isolates of Streptococcus pneumoniae Am. Soc. Microbiol., South Central Branch Meeting, 20042004
Quin, L.R., Dave, S., Carmicle, S.D., and McDaniel, L.S. Differential in vivo binding of complement regulator factor H to Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, 20042004
Quin, L.R., Carmicle, S., and McDaniel, L.S. Pneumococcal survival is increased in the host through recruitment of complement factor H by PspC Am. Soc. Microbiol., South Central Branch Meeting, 20042004
Carmicle, S.and McDaniel, L.S. The interaction of pneumococcal surface protein C and factor H on pneumococcal isolates from infective endocarditis Am. Soc. Microbiol., South Central Branch Meeting, 20042004
Moore, Q., Bosarge, J., and McDaniel, L.S. Protection against pneumococcal infection by prime-boost immunization with DNA and protein 4th International Symposium on Pneumococci and Pneumococcal Diseases. Helsinki, Finland. May, 20042004
Thornton, J., Rogers, D., and McDaniel, L.S.: Role of antibiotics in release of pneumolysin and subsequent inflammatory reactions 4th International Symposium on Pneumococci and Pneumococcal Diseases. Helsinki, Finland. May, 20042004
Carmicle, S., Dave, S., Quin, L.R., and McDaniel, L.S. The interaction of variants of pneumoccal surface protein C with factor H and the implication for pneumococcal survival in vivo 4th International Symposium on Pneumococci and Pneumococcal Diseases. Helsinki, Finland. May, 20042004
Thornton, J.A., and McDaniel, L.S. Characterization of a Tex homolog in Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, 2003.2003
Swords, W.E., McDaniel, L.S., and VonCannon, J. Discrete lipooligosaccharide glycoforms mediate differential host cell adherence by nontypeable Haemophilus influenzae Am. Soc. Microbiol. General Meeting, 20032003
Moore, III, Q.C., Bosarge, J.R., and McDaniel, L.S. DNA vaccination with pspA and protein elicits PspA specific antibody responses Am. Soc. Microbiol. General Meeting, 20032003
Zhou, X., Barber, H., Butkus, D.E., McDaniel, L.S., Mangilog, B., and McDaniel, O. IL-18 and IFN-γ genotype correlation with allograft function in african-american renal transplant patients Am. Soc. Human Immunogenetics, 20032003
Dave, S., Pangburn, M.K., Holloway, J., and McDaniel, L.S. Interaction of human complement proteins FH and C3 with PspA and PspC of Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, 20032003
McDaniel, L.S., Thornton, J.A. and Rogers, P.D. Pneumolysin induced inflammatory responses following antibiotic treatment of Streptococcus pneumoniae Infectious Dis. Soc. Annual Meeting, p.150-151, 20032003
He, X., and McDaniel, L.S. The influence of pneumococcal background on protection in mice immunized with PspA Am. Soc. Microbiol. General Meeting, 2003.2003
Quin, L.R., Dave, S., Carmicle, S., and McDaniel, L.S. The interaction of complement factor H with Streptococcus pneumoniae Am. Soc. Microbiol., South Central Branch Meeting, 20032003
McDaniel, L.S., Dave, S., Smith, L., and Carmicle, S. The role of PspC in the virulence of Streptococcus pneumoniae Microbial Pathogenesis and Host Response at Cold Spring Harbor Laboratory, p. 117, 20032003
Pruitt, C., Dave, S., Cameron, J., and McDaniel, L.S. Binding of human complement factor H by PspC of Streptococcus pneumonia Experimental Biology, 20022002
Dave, S., Pruitt, C., and McDaniel, L.S. Interaction of human complement factor H with PspC of Streptococcus pneumoniae Am. Soc. Microbiol., South Central Branch Meeting, 20022002
Thornton, J.A., Rogers, P.D., Barker, K.S., Chapman, B., Sacks, G., Swiatlo, E., and McDaniel, L.S. Microarray analysis identifies genes differently expressed in response to pneumolysin after exposure to Streptococcus pneumoniae Am. Soc. Microbiol., South Central Branch Meeting, 20022002
Thornton, J.A., Rogers, P.D., Barker, K.S., Chapman, B., Sacks, G., Swiatlo, E., and McDaniel, L.S. Pneumolysin-dependent differential gene expression identified by cDNA microarray analysis of THP-1 cells exposed to Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, 20022002
Moore, III, Q.C., Bosarge, J.R., and McDaniel, L.S. Protection against pneumococcal disease by genetic immunization. Annual Biomedical Research Conference for Minority Students, 2002.2002
Moore, III, Q.C., Bosarge, J.R., and McDaniel, L.S. Protection against pneumococcal infection by genetic immunization with pspA/EF5668 Am. Soc. Microbiol., South Central Branch Meeting, 20022002
Moore, III, Q.C., Bosarge, J.R., Ethridge, A.S., and McDaniel, L.S. Protection against Streptococcus pneumoniae by genetic immunization with pspA/EF5668. Am. Soc. Microbiol. General Meeting, 20022002
He, X., and McDaniel, L.S. Use of allelic replacement to study the biology of PspA 6th International Conference on Streptococcal Genetics, 20022002
He, X., and McDaniel, L.S. Use of allelic replacement to study the biology of PspA Am. Soc. Microbiol., South Central Branch Meeting, 20022002
McDaniel, L.S., and Thornton, J.A. Use of cDNA microarrays to analyze pneumococcal virulence factors XV Lancefield International Symposium on Streptococci and Streptococcal Diseases. Goa, India, October, 2002.2002
McDaniel, L.S., Bosarge, J.R., and Moore III, Q.C. Cross-protection elicited by genetic immunization with pspA 3rd International Symposium on Pneumococci and Pneumococcal Diseases. Anchorage, AK., May, 2002.2002
Pruitt, C., Dave, S., Cameron, J., and McDaniel, L.S. Binding of human complement factor H by PspC of Streptococcus pneumoniae Am. Soc. Microbiol., South Central Branch Meeting, 20012001
Bosarge, J.R., Ethridge, A., Moore, Q., and McDaniel, L.S.: DNA vaccination with regions within the α-helical domain of PspA/Rx1 protects against Streptococcus pneumoniae. Am. Soc. Microbiol. General Meeting, 20012001
He, X., Ethridge, A., and McDaniel, L.S. Immune response to the α-helical domain of PspA/EF5668 Am. Soc. Microbiol., South Central Branch Meeting, 20012001
Dave, S., Brooks-Walter, A., Hakansson, A., and McDaniel, L.S. Interaction of human complement factor H with PspC of Streptococcus pneumoniae Am.Soc. Microbiol. General Meeting, 20012001
Van Meter, C.J., Bosarge, J.R., and McDaniel, L.S. Localization of protection eliciting epitopes on PspA/EF5668 Am. Soc. Microbiol. General Meeting, 20012001
McDaniel, L.S. “Captain of the men of death”: The pneumococcal story Southern Association of Medicine and Science, Third Annual Conference, 20012001
McDaniel, L.S., and Bosarge, J.R. Anti-PspA specific antibodies elicited by genetic immunization are protective against pneumococcal challenge Am. Soc. Microbiol. General Meeting, 20002000
McDaniel, L.S., Dave, S., Bosarge, J., Swiatlo, E., McDaniel, O., and Brooks-Waler, A. Complement interactive proteins of Streptococcus pneumoniae The Lancefield Society Meeting, 20002000
Sanders, V., Watt, J., Swiatlo, E., Cameron, J., and McDaniel, L.S. Evidence for a sortase gene in Streptococcus pneumoniae Am. Soc. Microbiol., South Central Meeting, 20002000
Johnson, L., Watt, J., Swiatlo, E., and McDaniel, L.S. Families of PspA of Streptococcus pneumoniae isolates from Mississippi Am. Soc. Microbiol., South Central Branch Meeting, 20002000
Ethridge, A., and McDaniel, L.S. Localization of epitopes on PspA of Streptococcus pneumoniae recognized by monoclonal antibodies Am. Soc. Microbiol., South Central Branch Meeting, 20002000
Washington, L.B., Johnston, L., and McDaniel, L.S. PspA family typing of clinical isolates of Streptococcus pneumoniae J. Miss. Acad. Sciences, 2000, 45:512000
Sanders, V., Watt, J., Swiatlo, E., Cameron, J., and McDaniel, L.S. Evidence for a sortase gene in Streptococcus pneumoniae. Bridges Baccularate Program, Univ. of South Alabama, July, 20002000
Moore, E., Washington, L.B, and McDaniel, L.S. Analysis of pneuococcal clinical isolates by DNA hybridization using a fragment specific for pspA MS Acad. Sci., 44:53, 19991999
Bosarge,J., and McDaniel, L.S. Genetic immunization with the region of pspA encoding the α-helical domain elicits protection against the extracellular pathogen Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, p. 86, 19991999
McDaniel, L.S., Bosarge, J.R., and McDaniel, D.O. Immune response to PspA following genetic immunization with pspA Molecular Approaches to Vaccine Design Meeting at Cold Spring Harbor Laboratory, p. 60, 19991999
Sidie, K., Bosarge, J., and McDaniel, L.S. Immune response to PspA following genetic immunization with the region of pspA encoding the α-helical domain of PspA/Rx1. Am. Soc. Microbiol., South Central Branch Meeting, 19991999
Swiatlo, E. Moore, E., Watt, J., Cameron, J.A., and McDaniel, L.S. In vitro activity of four quinolones against clinical isolates of Pseudomonas aeruginosa Am. Soc. Microbiol. ICAAC, p. 247, 19991999
Caldwell,J.W., Hollingshead, S.K., Briles, D.E., and McDaniel, L.S. A Conserved Sequence of PspA Upstream of a Region Containing Protection-Eliciting Epitopes Am. Soc. Microbiol., General Meeting, 19981998
McNair, L., Moore, E., Watt, J., Swiatlo, E., Cameron, J.A., and McDaniel, L.S. Activity of trovafloxacin against clinical isolates of pneumococci, staphylococci, and enterococci Am. Soc. Microbiol., Southeastern and South Central Joint Branch Meeting, 1998.1998
Bosarge, J., and McDaneil, L.S. Expression of the α-helical domain of PspA in transfected HeLa Cells Am. Soc. Microbiol., Southeastern and South Central Joint Branch Meeting, 1998.1998
McDaniel, L.S., and Curiel, D.T. Genetic Immunization with pspA can Elicit Protection Against Pneumococcal Infection 5th International Streptococcal Genetics Meeting, Vichy, France. 19981998
Caldwell, J.W., Hollingshead, S.K., Briles, D.E., and McDaniel, L.S. Analysis of a conserved DNA sequence of pspA encoding cross-protection eliciting epitope(s) American Society for Microbiology, South Central Branch Meeting, 19971997
McDaniel, L.S., and Caldwell, J.W. DNA immunization with pspA can elicit protection against pneumococcal infection Microbial Pathogenesis and Host Response Meeting at Cold Spring Harbor Laboratory, 1997, p. 1841997
McDaniel, L.S., and Curiel, D.T. Protection against Streptococcus pneumoniae following immunization with a plasmid expressing PspA Am. Soc. Microbiol. General Meeting, 19971997
McDaniel, L. S. and Hill, W. E. Survival of recombination-deficient mutants of Escherichia coli during incubation with nalidixic acid. South Central Branch of the American Society for Microbiology, 1977.1997
Briles, D.E., King, J., McDaniel, L.S., Swiatlo, E., and Forman, C. Cross-protection elicited by individual PspAs in mice challenged with Streptococcus pneumoniae Am. Soc. Microbiol., 1996, p.561996
Ralph, B.A., Briles, D.E., and McDaniel, L.S. Evidence that the repeat region of PspA does not elicit protection against infection with Streptococcus pneumoniae Am. Soc. Microbiol. General Meeting, 1996, p.54.1996
McDaniel, L.S., McDaniel, D. O., and Hollingshead, S.K. Sequencing of the gene encoding a serologically varied, but cross-protective PspA of Streptococcus pneumoniae EF5668 Am. Soc. Microbiol. General Meeting, 19961996
Ralph, B.A., Briles, D.E., and McDaniel, L.S. Protection elicited against fatal pneumococcal infection by the C-terminal half of pneumococcal surface protein A (PspA) Am. Soc. Microbiol. Meeting, 19951995
McDaniel, L.S., Brooks-Walter, A., Hollingshead, S.K., Crain, M.J., and Briles, D.E. pspA gene families detected by PCR-restriction fragment length polymorphism analysis Lancefield Soc. Meeting, 19951995
Brooks-Walter, A., McDaniel, L.S., Hollingshead, S.K., Crain, M.J., and Briles, D.E. RFLP of the pspA gene from different isolates of Streptococcus pneumoniae reveal families of pspA ICAAC, 1995, p. 281995
Tart, R. C., McDaniel, L.S., Ralph, B.A., and Briles, D.E. Truncated Streptococcus pneumoniae PspA molecules elicit protective immunity against fatal pneumococcal challenge in mice ICAAC, 1995, p. 281995
Ralph, B.A., Briles, D.E., and McDaniel, L.S. Cross-reactive protection eliciting epitopes of pneumococcal surface protein A (PspA) Am. Soc. Microbiol. Meeting, 1994, p. 1481994
Swiatlo, E., Briles, D.E., and McDaniel, L.S. Genetic analysis of pneumococcal surface protein A (pspA) ICAAC, 1994, p. 2351994
McDaniel, L.S., Ralph, B.A., Hollingshead, S.K., and Briles, D.E. Protection-elicited by the C-terminal half of PspA and analysis of diversity of pspA Lancefield Soc. Meeting, 19941994
Brooks-Walter, A., Crain, M.J., Briles, D.E., and McDaniel, L.S. Restriction fragment length polymorphism analysis of the pneumococcal surface protein A (PspA) of Streptococcus pneumoniae Am. Soc. Microbiol. Meeting, 1994, p. 1071994
Stover, C. K., Langermann, S., Hanson, M.S., Burlein, J. E., Palasdzynski, S. R., McDaniel, L. S., and. Briles, D. E. Candidate pneumococcal vaccines based on the recombinant BCG vaccine vehicle Am. Soc. Microbiol, Meeting, 1993, p. 1561993
Brooks-Walter, A., Briles, D.E., and McDaniel, L.S. Detection of Streptococcus pneumoniae in body fluids by polymerase chain reaction ICAAC, 19931993
Briles, D.E., Cairns, B., Forman, C., Yother, J., and. McDaniel, L.S Full length pneumococcal surface protein A (PspA) injected without adjuvant is able to elicit protection against otherwise fatal pneumococcal infections Am. Soc. Microbiol. Meeting, 1993, p. 1561993
Swiatlo, E. Briles, E., D., and McDaniel, L. Genetic analysis of Pneumococcal Surface Protein A (PspA) using southern blot hybridization with oligonucleotide probes Am. Soc. Microbiol. Meeting, 1993, p. 1071993
McDaniel, L. S., Forman, C., and McDaniel, D. O. Pneumococcal surface protein A (PspA) type 12 elicits protection against pneumococci of different capsular and PspA types Am. Soc. Microbiol. Meeting, 1993, p. 611993
McDaniel, L.S., Stover, C.K. and McDaniel, D.O. Cloning and expression in Escherichia coli of an amplified pspA gene of type 12 PspA from a capsular type 14 Streptococcus pneumoniae Am. Soc. Microbiol. Meeting, 1992, p. 701992
Cairns, B. A., Briles, D. E., and McDaniel, L. S. Mapping protection eliciting epitopes of pneumococcal surface protein A (PspA) Am. Soc. Microbiol. Meeting, 1992, p. 701992
Sheffield, J. S., and McDaniel, L. S. Analysis of the immunogenic potential of a type 4 pneumococcal surface protein A (PspA) Am. Soc. Microbiol., 1991, p. 971991
McDaniel, L.S., Sheffield, J.S., Yother, J., and Briles, D.E. Localization of protection eliciting epitopes and molecular diversity of PspA Lancefield Soc. Meeting, 19911991
McDaniel, L. S., Yang, C.Y., Sheffield, J. S., and Yother, J. Localization of protective epitopes on PspA (pneumococcal surface protein A) Am. Soc. Microbiol., 1991, p. 311991
Briles, D.E., Yother, J., McDaniel, L., and Crain, M. Pneumococcal surface protein A: Role in pathogenesis and vaccine development Am. Soc. Micorobiol. Biotechnology Conf., 19911991
Steinbronn, J. L., Briles, D. E., and McDaniel, L.S. Identification and immunological analysis of protective pneumococcal surface proteins National Medical Student Research Conference, 19901990
McDaniel, L. S., Steinbronn, J. L., and Briles, D. E. Molecular cloning and analysis of recombinant PspA (pneumococcal surface protein A) Am. Soc. Microbiol. Third Conference on Streptococcal Genetics, 19901990
Hughes, T. E. and McDaniel, L. S. Analysis of a surface protein from a PspA (pneumococcal surface protein A) mutant, Alabama Acad. Sci., 1989.1989
McDaniel, L. S., Bowen, P. and Briles, D. E. Molecular cloning of the gene encoding PspA (pneumococcal surface protein A) and analysis of protective immunity induced by PspA Am. Soc. Microbiol., 1989, p. 1251989
McDaniel, L. S., Forman, C. and Briles, D. E. Analysis of protection eliciting pneumococcal cell surface components from PspA (pneumococcal surface protein A) mutants FASEB J. 1988, 2:A12571988
Yother, J., McDaniel, L. S. and Briles, D. E. A pneumococcal surface protein that is necessary to protect pneumococci from complement dependent killing in serum and blood Fed. Proc. 1987, 46(3):6111987
McDaniel, L. S., Forman, C. and Briles, D. E. Analysis of Protective antibody responses elicited by PspA (pneumococcal surface protein A) mutants Am. Soc. Microbiol. 1987. p. 471987
Waltman, W. D., II and McDaniel, L. S. Differences in the molecular weights of specific proteins in Streptococcus pneumoniae Am. Soc. Microbiol. 1987. p. 3391987
Yother, J., McDaniel, L. S. and Briles, D. E. Pneumococcal surface protein A (PspA) prevents complement-dependent killing of Streptococcus pneumoniae Am. Soc. Microbiol. 1987. p.471987
McDaniel, L. S., Vijayakumar, M. and Guild, W. R. Generation of a plasmid that can insertionally inactivate a gene necessary for the production of pneumococcal surface protein 1 (PSP1) Am. Soc. Microbiol. 1986. p. 1381986
Carroll, J. M. and McDaniel, L. S. Immunochemical characterization of pneumococcal surface antigens J. Alabama Acad. Sci. 1986, 57:115.1986
Briles, D. E., McDaniel, L. S., Yother, J., Fischetti, V. and Widenhofer, K. Surface proteins that can behave as type 1 or 2 antigens depending on whether or not the bacteria expressing them carry anti-phagocytic molecules International Congress in Immunology. 19861986
Waltman, W. D. II, McDaniel, L. S., Rhee, S. S. and Briles, D. E. The potential for serotyping Streptococcus pneumoniae based on the presence of surface protein antigens Am. Soc. Microbiol. 1986. p. 3461986
Yother, J. McDaniel, L. S., and Briles, D. E. Transformation of encapsulated pneumococci with chromosomal and plasmid DNA Am. Soc. Microbiol. 1986. p. 1431986
McDaniel, L. S., Scott, G., Widenhofer, K. and Briles, D. E. A monoclonal antibody that reacts with a common antigen of Streptococcus pneumoniae and can protect mice from infection Amer. Soc. Microbiol. 1985. p. 881985
McDaniel, L. S., Scott, G. and Briles, D. E. Characterization of monoclonal antibodies against cell surface proteins of Streptococcus pneumoniae Amer. Soc. Microbiol. 1984. p. 30.1984
McDaniel, L. S., Widenhofer, K. and Briles, D. E. Immunochemical analysis of cell surface protein antigens of Streptococcus pneumoniae Amer. Soc. Microbiol. 1984. p. 291984
Acton, R. T., McDaniel, L. S. and McDaniel, D. O. Modification of NK cell activity by monoclonal antibodies to target cell glycoproteins Fed. Proc. 1984, 43:17581984
McDaniel, L. S., Scott, G., Svanborg-Eden, C. and Briles, D. E. Monoclonal antibodies against surface polypeptides on mouse virulent strains of Streptococcus pneumoniae Fed. Proc. 1984, 43:14521984
McDaniel, L. S. and Briles, D. E Blood clearance by anti-phosphocholine antibodies as a mechanism of protection in experimental pneumococcal bacteremia Amer. Soc. Microbiol. 1983. p. 831983
McDaniel, L. S. and Briles, D. E. Monoclonal antibodies that protect against infection with Streptococcus pneumoniae and appear to recognize a surface polypeptide Fed. Proc. 1983, 42:10891983
McDaniel, L. S., Benjamin, W. H., Jr. and Briles, D. E. Effects of anti-phosphocholine antibodies on in vivo clearance and killing of Streptococcus pneumoniae XIII International Congress of Microbiol. 1982. p. 1141982
McDaniel, L. S. and Cozad, G. C. Suppression of murine EL4 lymphoma by Blastomyces dermatitidis. Amer. Soc. Microbiol. 1981. p. 325.1981
McDaniel, L. S., and Cozad, G. C. Functional activity of peritoneal macrophages activated by Blastomyces dermatitidis Amer. Soc. Microbiol. 1980. p. 3301980
McDaniel, L. S. and Cozad G. C. Phagocytic studies of peritoneal macrophages activated by Blastomyces dermatitidis. Oklahoma Acad. Sci. 1979.1979
McDaniel, L. S. and Hill, W. E. Sensitivity of recombination-deficient mutants of Escherichia coli to nalidixic acid Amer. Soc. Microbiol. 1979. p. 123.1979

Book Chapter

Briles, D.E., Hollingshead, S.K., Swiatlo, E., Brooks-Walters, A., Szalai, A., Virolainen, A., McDaniel, L.S., Benton, K.A., Aerts, P.C., van Dijk, H., and Crain, M.J. Pneumococcal proteins PspA and PspC: Their potential for use as vaccines In: A. Tomasz ed. Streptococcus pneumoniae: Molecular Biology and Mechanisms of Disease. Marry Ann Liebert, Inc., Larchmount, NY, p. 253-260, 20002000
Briles, D. E., Horwitz, J., McDaniel, L. S., Benjamin, W. H., Jr., Claflin, J. L., Booker, C. L., Scott, G., and Forman, C. Genetic control of susceptibility to pneumococcal infection In: D. E. Briles and M. D. Cooper, eds., Current Topics in Microbiology and Immunology: Genetic Control of the Susceptibility to Bacterial Infection. Springer-Verlag GmBh and Co. KG., p. 124:103-120, 19861986
McDaniel, L. S. and Briles, D. E. Protective effects of antibodies to pneumococcal cell wall proteins In: D. Schlessinger, ed., Microbiology - 1985, Amer. Soc. Microbiol., Washington, D. C., p. 103-105, 19851985

Presentations

Invited Symposia, Release of pneumolysin during exponential growth, UAB Pneumococcal Symposium, Department of Microbiology, University of Alabama at Birmingham, University of Alabama at Birmingham, Birmingham, AL10/2010
National and International Invited Seminars/Lectures, Pneumococcal responses during ocular infections., University of Siena, University of Siena, Siena, Italy.09/2010
Invited Symposia, Acinetobacter baumannii serine protease is required for serum resistance and biofilm dispersal., 8th International Symposium on the Biology of Acinetobacter, Universita di Roma, Universita di Roma Tre, Rome, Italy.09/2010
Invited Symposia, Host-Pathogen Interactions during Streptococcus pneumoniae Colonization and Infection., Elliott Nowell White Science Symposium, Delta State University, Delta State University, Cleveland, MS.10/2008
Invited Symposia, Characterization of PcsB of Streptococcus pneumoniae: Localization, Conservation, and Immunogenicity, UAB Pneumococcal Symposium, Department of Microbiology, University of Alabama at Birmingham, University of Alabama at Birmingham, Birmingham, AL07/2008
Invited Symposia, The Odyssey., UAB Pneumococcal Symposium, Department of Microbiology, University of Alabama at Birmingham, July 24-25, University of Alabama at Birmingham, Birmingham, AL.07/2008
Invited Symposia, Pneumococcal proteins as vaccine candidates, 9th International Symposium on Recent Advances in Otitis Media, St. Petersburg Beach, FL07/2007
National and International Invited Seminars/Lectures, Bacterial and host responses during infection with Streptococcus pneumoniae., Department of Molecular Biology and Immunology, University of North Texas Health Sciences Center, University of North Texas Health Sciences Center, Fort Worth, TX10/2006
Invited Symposia, Pneumococcal DNA vaccines., UAB Pnemocaccal Symposium, Department of Microbiology, University of Alabama at Birmingham, University of Alabama at Birmingham, Birmingham, AL.08/2006
Invited Symposia, Pneumococcal Evasion of Early Innate Immune Responses., UAB Pnemocaccal Symposium, Department of Microbiology, University of Alabama at Birmingham, University of Alabama at Birmingham, Birmingham, AL.08/2006
State/Local Invited Seminars/Lectures, Pneumolysin: A multifunctional toxin of Streptococcus pneumoniae, Department of Biochemistry, University of Mississippi Medical Center, University of Mississippi Medical Center, Jackson, MS.2006
State/Local Invited Seminars/Lectures, Molecular cloaking by Streptococcus pneumoniae., Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, Louisiana State University Health Sciences Center, New Orleans, LA.2005
National Center for Natural Products Research, The Pneumococcus: A Model System for Discovery, National Center for Natural Products Research, The University of Mississippi, University, MS.2004
University Wide Research Seminar, The Enduring Pnuemococcus: New Insights into a Prototypical Pathogen, University Wide Research Seminar, University of Mississippi Medical Center, University of Mississippi Medical Center, Jackson, MS.2003
Regional Invited Seminars/Lectures, The Interaction of Human Complement Factor H with Streptococcus pneumoniae, Department of Molecular Sciences, University of Tennessee Health Science Center, University of Tennessee Health Science Center, Memphis, TN.2003
National and International Invited Seminars/Lectures, Bacterial and host responses during infection with Streptococcus pneumoniae, Department of Infectious Diseases, Creighton University/Veterans Administration Medical Center, Creighton University/Veterans Administration Medical Center, Omaha, NE.2002
Invited Symposia, Pneumococcal DNA vaccines., The Pneumococcal Laboratory Symposium, Department of Microbiology, University of Alabama at Birmingham, University of Alabama at Birmingham, Birmingham, AL.2001
State/Local Invited Seminars/Lectures, “Captain of the Men of Death”: The Pneumococcal Story, The Reynolds Historical Lecture. University of Alabama at Birmingham, University of Alabama at Birmingham, Birmingham, AL.2001
National and International Invited Seminars/Lectures, Genetic immunization with pspA protects against Streptococcus pneumoniae infection., Department of Biological Sciences, Alabama State University, Alabama State University, Montgomery, AL2000
National and International Invited Seminars/Lectures, Host-parasite interactions of the pneumococcus, Department of Microbiology, University of Alabama at Birmingham, University of Alabama at Birmingham, Birmingham, AL.1999
National and International Invited Seminars/Lectures, Immune responses against PspA., Eijkman-Winkler Laboratory of Medical Microbiology, University of Utrecht, University of Utrecht, the Netherlands1998
State/Local Invited Seminars/Lectures, The pneumococcus: Possible vaccine development, Guest lecturer for honors biology seminar, Millsaps College, Jackson, MS1997
National and International Invited Seminars/Lectures, Pneumococcal protein antigens., Amer. Soc. Microbiol. General Meeting, Washington, DC1995
National and International Invited Seminars/Lectures, Prospects for a protein based pneumococcal vaccine., 18th International Congress of Chemotherapy., Stockholm, Sweden.1993
Regional Invited Seminars/Lectures, PspA encodes a major protection eliciting protein on Streptococcus pneumoniae, Montgomery, AL, Alabama State University1990
Regional Workshop Program., Principal and procedures of monoclonal antibody preparation., Amer. Soc. Microbiol. Regional Workshop Program, Boston, MA.1987
Scientific Presentations, Studies on PspA (pneumococcal surface protein A) insertionally inactivated mutants., Amer. Soc. Micro. Second Conference on Strep. Genet., Miami, FL1986
Abstract from American Society of Microbiology, Protective effects of antibodies to pneumococcal cell wall proteins. Amer. Soc. Microbiol. p.XVI.1984

Honors, Awards, and Recognition

Elected to Fellowship in the American Academy of Microbiology, American Academy of Microbiology2008
Fellow of the Infectious Diseases Society of America, University of Mississippi Medical Center2008
Excellence in Research Award, University of Mississippi Medical Center
B.S. in Microbiology cum laude, Southeastern Louisiana University
NIH Postdoctoral Traineeship, Immunology and Pathogenesis, University of Alabama at Birmingham
Excellence in Research Award, University of Mississippi Medical Center
Weekly editorialist on animal health for Gulf Dairy Assn. Newsletter
President of the Lancefield Society
Member of the American Society for Microbiology
Member of the Phi Sigma Society
Member of the Reticuloendothelial Society
Member of the American Association of Immunologist
President of the Mississippi Academy of Sciences

Professional Membership and Service

mBio, Editorial board (founding member)2010 - Present
American Heart Association, Reviewer, Grant Proposal, Co-Chairman R1 Microbiology and Microbial Pathogenesis Committee2009 - Present
Infection and Immunity, Editorial board2009 - Present
American Academy of Microbiology, Fellow2008 - Present
American Academy of Microbiology Committees, Member, Maurice Hilleman/Merck Award Selection Committee2008 - Present
American Society for Microbiology, Workshop Organizer, Presentation Institute2008 - Present
American Heart Association, Reviewer, Grant Proposal2007 - Present
Molecular Microbiology, Reviewer, Ad Hoc Reviewer2007 - Present
American Association for Immunology, Editor, Associate Editor, Journal of Immunology2006 - Present
The Journal of Immunology, Editor, Associate Editor2006 - 2010
Infectious Disease Society of America, Fellow2005 - Present
Vaccine, Reviewer, Ad Hoc Reviewer2005 - Present
The Israel Science Foundation, Reviewer, Grant Proposal2005 - 2007
Mississippi Academy of Sciences, Officer, President/Elect/Past2005 - 2006
Journal of Clinical Microbiology2004 - Present
The Israel Science Foundation Reviewer, Reviewer, Grant Proposal2004 - 2007
Frontiers in Bioscience, Editor, Journal Editor2002 - Present
Journal of Infectious Diseases, Reviewer, Ad Hoc Reviewer2002 - Present
The Journal of Immunology, Reviewer, Ad Hoc Reviewer2002 - 2006
Emerging Infectious Diseases, Reviewer, Ad Hoc Reviewer2002
Meningitis Research Foundation, Reviewer, Ad Hoc Reviewer, Reviewer2000 - 2002
Minority Access to Research Careers (MARC)1998 - 2006
Infection and Immunity1997 - 2009
American Society for Microbiology, Reviewer, Ad Hoc Reviewer, Reviewer of American Society for Microbiology minority faculty fellowships1997 - 1998
American Sociey for Microbiology, Committee Member, Minority pre-doctoral Watkins fellowships1996 - 2007
Jackson State University Bridges to Baccalaureate, Mentor1996 - 2006
Mycology and Bacteriology Study Section 2 (MBC-2), Reviewer, Ad Hoc Reviewer1995 - 1997
American Association for Immunology, Member1984 - Present
University of Alabama at Birmingham, Immunology and Pathogenesis1981 - 1984
American Society for Microbiology, Member1974 - Present
American Association of Immunologist, Member
American Society for Microbiology, Member
Infectious Disease Society of America, Fellow
Phi Sigma Society, Member
Reticuloendothelial Society, Member
American Society for Microbiology-Pan American Health Organization Scientific, Facilitator, American Society for Microbiology-Pan American Health Organization Scientific Writing and Publishing Workshop, San Jose, Costa Rica2010
Am. Soc. for Microbiology, Mentor, Mentor for Am. Soc. for Microbiology Writing/Pub Workshop (grad. stud/post doc.)2010
SURE Undergraduate Research, Mentor2010
American Heart Association, Reviewer, Grant Proposal, R2 Immunology and Virology Committee2008
American Society for Microbiology, Invited Lecture, American Society for Microbiology Presentation Institute2008
American Heart Association, Reviewer, Grant Proposal, Southern/Ohio Valley Research Consortium, Peer Review Committee, 4a2007
American Society for Microbiology and American Physiology Society, Invited Lecture, American Society for Microbiology and American Physiology Society Writing Workshop2006
Phillip Morris External Research Program, Reviewer, Grant Proposal2005
The Wellcome Trust, Reviewer, Ad Hoc Reviewer2000
Special Emphasis Panel Study Section, Vaccine Centers, Member1999
Special Emphasis Panel Study Section, MBC, Member1998
Veterans Administration, Reviewer, Grant Proposal, Merit Review Application Reviewer1997

Committee Service

Microbiology Faculty Promotions Committee, Chair2009 - Present
School Of Graduate Studies - Curriculum Committee, Member2008 - Present
Biomedical Institutional Grant Committee, Member

Community Service

SURE Undergraduate Research, Mentor2010 - 2019
The Lancefield Society, President2001 - 2003
Minority Access to Research Careers (MARC), Program Mentor1998 - 2006
Tougaloo College summer program, Mentor1997 - 2005
Jackson State University Bridges to Baccalaureate, Mentor1996 - 2006
Base Pair Program (high school students), Mentor1996 - 2008
MSRP Summer Student Research Fellowship, Mentor1995 - 2019
Gulf Dairy Assn. Newsletter, Weekly editorialist on animal health1974 - 1976

Other Service

Publication Committee for the Infectious Diseases Society of America, Committee2016 - 2020
Member of American Heart Association Task Force to review Scientific Subgroups, Member2009 - Present
Department of Microbiology Executive Committee, Member06/2007 - Present
VA Institutional Animal Care and Use Committee, Chairman2006 - Present

Teaching Experience

725, Graduate, Course, Course Director, Bacterial Structure and Function 2011
Lecture, Course Director, Advanced Bacteriology Course for Graduate Students

Directed Student Learning

Master's Thesis Committee Chair, Advised: Lauren King2010 - 2010
Dissertation Committee Chair, Advised: Chinwendu Onwubiko, Megumi Mills, Lauren King2004 - 2011
Doctoral Advisory Committee Member, Advised: Sandhya Dave2004 - 2004
Master's Thesis Committee Member, Advised: Jason Caldwell2000 - 2000
Dissertation Committee Member, Advised: Pratik Shah, Melissa Sanders
Doctoral Advisory Committee Member, Advised: Megumi F. Mills
Doctoral Advisory Committee Member, Advised: Lisa Quin
Doctoral Advisory Committee Member, Advised: Quincy C. Moore, III
Doctoral Advisory Committee Member, Advised: Xiangyun He
Doctoral Advisory Committee Member, Advised: Justin Thornton
Doctoral Advisory Committee Member, Advised: Joseph Bosarge

Fellows supervised

Post Doctoral for Stephanie Carmicle-Davis, Advisor/Trainer/Mentor, 1 fellows supervised