Ji Li, PhD

Professor

Department:
SOM-Physiology & Biophysics

Email:
jli3@umc.edu

Work Phone:
(601) 815-8995

Biography

Dr. Ji Li is a nationally recognized senior-level research scientist as demonstrated by a continuous record of research productivity and independent funding, for at least 17 years. Dr. Li serves on the local medical fellow education committee, he organized and hosted numerous research seminars. Dr. Li served on admission committee and steering committee of the PhD Program of Biomedical Sciences. At national level, he has served as peer-reviewed committee member of VA CARA (Cardiovascular Studies-A) Study Section for over 10 years, besides serving on NIH and DoD grant review panels since 2013. Dr. Li was tapped to serve as Editor-in-Chief for Pharmaceutical Regulatory Affairs journal, and Associate Editor for Life Sciences journal and Frontiers in Cardiovascular Medicine journal. Dr. Li was Chapter Councilor of ASPET (The American Society for Pharmacology and Experimental Therapeutics) upstate New York Pharmacology Society.

Education

Yale University School of Medicine, Postdoc, Physiology	2002
National Institute on Aging/NIH, Visiting Scholar, Signal Transduction	2000
Sichuan University, Postdoc, Molecular Medicine	1998
Lanzhou University, PhD, Cell Biology	1998
Lanzhou University, MS, Biophysics	1992
Lanzhou University, BS, Biochemistry	1989

Current Positions

Professor, School of Medicine	05/2023 - Present
Co-Director, School of Medicine	05/2023 - Present
The University of Mississippi Medical Center Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Professor, University of South Florida, School of Medicine	07/2019 - 05/2023
Associate Director, Mississippi Center for Heart Research, School of Medicine	09/2015 - 06/2019
Associate Professor, University of Mississippi Medical Center, School of Medicine, Department of Physiology And Biophysics	07/2015 - 06/2019
Assistant Professor, University at Buffalo-SUNY, School of Medicine	08/2009 - 06/2015
Director, University of Wyoming, School of Pharmacy	2008 - 07/2009
Assistant Professor, University of Wyoming, School of Pharmacy	08/2007 - 07/2009
Associate Research Scientist, Yale University, School of Medicine	07/2003 - 07/2007
Instructor, Xiamen University	09/1992 - 08/1995

Publications

Journal Article
Fatmi MK, Wang H, Slotabec L, Wen C, Seale B, Zhao B, Li J, Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C. Aging, 2024 Feb 21;16(4):3137-3159	2024
Wang H, Slotabec L, Didik S, Li Z, Leng L, Zhao B, Bucala R, Li J, A small molecule macrophage migration inhibitory factor agonist ameliorates age-related myocardial intolerance to ischemia-reperfusion insults via metabolic regulation. Metabolism: clinical and experimental, 2024 Apr;153:155792	2024
Zoungrana LI, Krause-Hauch M, Wang H, Fatmi MK, Li Z, Slotabec L, James AS, Didik S, Li J, Activated protein C signaling mediates neuroinflammation in seizure induced by pilocarpine. Biochemistry and biophysics reports, 2023 Sep;35:101550	2023
Zhang J, Wang H, Slotabec L, Cheng F, Tan Y, Li J, Alterations of SIRT1/SIRT3 subcellular distribution in aging undermine cardiometabolic homeostasis during ischemia and reperfusion. Aging cell, 2023 Sep;22(9):e13930	2023
Didik S, Wang H, James AS, Slotabec L, Li J, Sestrin2 as a Potential Target in Hypertension. Diagnostics (Basel, Switzerland), 2023 Jul 14;13(14)	2023
Bates L, Krause-Hauch M, Wang H, Fatmi MK, Li Z, Chen Q, Ren D, Li J, Lesnefsky EJ, Acute, High Dose Metformin Therapy at Reperfusion Decreases Infarct Size in the High-Risk Aging Heart. Aging and disease, 2023 Oct 1;14(5):1488-1491	2023
Li Z, Wang H, Zoungrana LI, James A, Slotabec L, Didik S, Fatmi MK, Krause-Hauch M, Lesnefsky EJ, Li J, Administration of metformin rescues age-related vulnerability to ischemic insults through mitochondrial energy metabolism. Biochemical and biophysical research communications, 2023 Jun 4;659:46-53	2023
Iglesias M, Wang H, Krause-Hauch M, Ren D, Zoungrana LI, Li Z, Zhang J, Wei J, Yadav N, Patel K, Fatmi MK, Liu R, Lesnefsky EJ, Li J, Sestrin2 Mediates Metformin Rescued the Age-Related Cardiac Dysfunctions of Cardiorenal Syndrome Type 3. Cells, 2023 Mar 8;12(6)	2023
Fatmi MK, Ren D, Fedorova J, Zoungrana LI, Wang H, Davitt K, Li Z, Iglesias M, Lesnefsky EJ, Krause-Hauch M, Li J, Cardiomyocyte Pdk4 response is associated with metabolic maladaptation in aging. Aging cell, 2023 Apr;22(4):e13800	2023
Van Le TN, Zoungrana LI, Wang H, Fatmi MK, Ren D, Krause-Hauch M, Li J, Sirtuin 1 aggravates hypertrophic heart failure caused by pressure overload via shifting energy metabolism. Biochemical and biophysical research communications, 2022 Dec 31;637:170-180	2022
Krause-Hauch M, Fedorova J, Zoungrana LI, Wang H, Fatmi MK, Li Z, Iglesias M, Slotabec L, Li J, Targeting on Nrf2/Sesn2 Signaling to Rescue Cardiac Dysfunction during High-Fat Diet-Induced Obesity. Cells, 2022 Aug 22;11(16)	2022
Kim M, Nikouee A, Zou R, Ren D, He Z, Li J, Wang L, Djukovic D, Raftery D, Purcell H, Promislow D, Sun Y, Goodarzi M, Zhang QJ, Liu ZP, Zang QS, Age-Independent Cardiac Protection by Pharmacological Activation of Beclin-1 During Endotoxemia and Its Association With Energy Metabolic Reprograming in Myocardium-A Targeted Metabolomics Study. Journal of the American Heart Association, 2022 Jul 19;11(14):e025310	2022
Zoungrana LI, Krause-Hauch M, Wang H, Fatmi MK, Bates L, Li Z, Kulkarni P, Ren D, Li J, The Interaction of mTOR and Nrf2 in Neurogenesis and Its Implication in Neurodegenerative Diseases. Cells, 2022 Jun 28;11(13)	2022
Zhou H, Li J, Su H, Li J, Lydic TA, Young ME, Chen W, BSCL2/Seipin deficiency in hearts causes cardiac energy deficit and dysfunction via inducing excessive lipid catabolism. Clinical and translational medicine, 2022 Apr;12(4):e736	2022
Ren D, Fedorova J, Davitt K, Van Le TN, Griffin JH, Liaw PC, Esmon CT, Rezaie AR, Li J, Activated Protein C Strengthens Cardiac Tolerance to Ischemic Insults in Aging. Circulation research, 2022 Jan 21;130(2):252-272	2022
Hu M, Li J, Baker PN, Tong C, Revisiting preeclampsia: a metabolic disorder of the placenta. The FEBS journal, 2022 Jan;289(2):336-354	2022
Li X, Lu Q, Qiu Y, do Carmo JM, Wang Z, da Silva AA, Mouton A, Omoto ACM, Hall ME, Li J, Hall JE, Direct Cardiac Actions of the Sodium Glucose Co-Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure-Overload Heart Failure. Journal of the American Heart Association, 2021 Mar 16;10(6):e018298	2021
Zhang J, He Z, Fedorova J, Logan C, Bates L, Davitt K, Le V, Murphy J, Li M, Wang M, Lakatta EG, Ren D, Li J, Alterations in mitochondrial dynamics with age-related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility. Aging cell, 2021 Jul;20(7):e13419	2021
Ren D, He Z, Fedorova J, Zhang J, Wood E, Zhang X, Kang DE, Li J, Sestrin2 maintains OXPHOS integrity to modulate cardiac substrate metabolism during ischemia and reperfusion. Redox biology, 2021 Jan;38:101824	2021
Ren D, Quan N, Fedorova J, Zhang J, He Z, Li J, Sestrin2 modulates cardiac inflammatory response through maintaining redox homeostasis during ischemia and reperfusion. Redox biology, 2020 Jul;34:101556	2020
Han Y, Sun W, Ren D, Zhang J, He Z, Fedorova J, Sun X, Han F, Li J, SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion. Redox biology, 2020 Jul;34:101538	2020
Sun X, Han F, Lu Q, Li X, Ren D, Zhang J, Han Y, Xiang YK, Li J, Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet-Induced Obese Mice. Diabetes, 2020 Jun;69(6):1292-1305	2020
Lu Q, Liu J, Li X, Sun X, Zhang J, Ren D, Tong N, Li J, Empagliflozin attenuates ischemia and reperfusion injury through LKB1/AMPK signaling pathway. Molecular and cellular endocrinology, 2020 Feb 5;501:110642	2020
Zhang J, Ren D, Fedorova J, He Z, Li J, SIRT1/SIRT3 Modulates Redox Homeostasis during Ischemia/Reperfusion in the Aging Heart. Antioxidants (Basel, Switzerland), 2020 Sep 13;9(9)	2020
Liu J, Li X, Lu Q, Ren D, Sun X, Rousselle T, Li J, Leng J, AMPK: a balancer of the renin-angiotensin system. Bioscience reports, 2019 Sep 30;39(9)	2019
Hu H, Li X, Ren D, Tan Y, Chen J, Yang L, Chen R, Li J, Zhu P, The cardioprotective effects of carvedilol on ischemia and reperfusion injury by AMPK signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019 Sep;117:109106	2019
Yang L, Wang S, Ma J, Li J, Yang J, Bucala R, Ren J, CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy. Biochimica et biophysica acta. Molecular basis of disease, 2019 Sep 1;1865(9):2368-2378	2019
Ren D, Giri H, Li J, Rezaie AR, The Cardioprotective Signaling Activity of Activated Protein C in Heart Failure and Ischemic Heart Diseases. International journal of molecular sciences, 2019 Apr 10;20(7)	2019
Mohsin AA, Chen Q, Quan N, Rousselle T, Maceyka MW, Samidurai A, Thompson J, Hu Y, Li J, Lesnefsky EJ, Mitochondrial Complex I Inhibition by Metformin Limits Reperfusion Injury. The Journal of pharmacology and experimental therapeutics, 2019 May;369(2):282-290	2019
Lu Q, Li X, Liu J, Sun X, Rousselle T, Ren D, Tong N, Li J, AMPK is associated with the beneficial effects of antidiabetic agents on cardiovascular diseases. Bioscience reports, 2019 Feb 28;39(2)	2019
Li X, Liu J, Lu Q, Ren D, Sun X, Rousselle T, Tan Y, Li J, AMPK: a therapeutic target of heart failure-not only metabolism regulation. Bioscience reports, 2019 Jan 31;39(1)	2019
Li X, Liu J, Hu H, Lu S, Lu Q, Quan N, Rousselle T, Patel MS, Li J, Dichloroacetate Ameliorates Cardiac Dysfunction Caused by Ischemic Insults Through AMPK Signal Pathway-Not Only Shifts Metabolism. Toxicological sciences : an official journal of the Society of Toxicology, 2019 Feb 1;167(2):604-617	2019
Chen X, Li X, Zhang W, He J, Xu B, Lei B, Wang Z, Cates C, Rousselle T, Li J, Activation of AMPK inhibits inflammatory response during hypoxia and reoxygenation through modulating JNK-mediated NF-κB pathway. Metabolism: clinical and experimental, 2018 Jun;83:256-270	2018
Wang L, Quan N, Sun W, Chen X, Cates C, Rousselle T, Zhou X, Zhao X, Li J, Cardiomyocyte-specific deletion of Sirt1 gene sensitizes myocardium to ischaemia and reperfusion injury. Cardiovascular research, 2018 May 1;114(6):805-821	2018
Quan N, Wang L, Chen X, Luckett C, Cates C, Rousselle T, Zheng Y, Li J, Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway. Journal of molecular and cellular cardiology, 2018 Feb;115:170-178	2018
Cates C, Rousselle T, Wang J, Quan N, Wang L, Chen X, Yang L, Rezaie AR, Li J, Activated protein C protects against pressure overload-induced hypertrophy through AMPK signaling. Biochemical and biophysical research communications, 2018 Jan 22;495(4):2584-2594	2018
Feng R, Liu J, Wang Z, Zhang J, Cates C, Rousselle T, Meng Q, Li J, The structure-activity relationship of ginsenosides on hypoxia-reoxygenation induced apoptosis of cardiomyocytes. Biochemical and biophysical research communications, 2017 Dec 16;494(3-4):556-568	2017
Xue M, Chen X, Guo Z, Liu X, Bi Y, Yin J, Hu H, Zhu P, Zhuang J, Cates C, Rousselle T, Li J, L-Carnitine Attenuates Cardiac Dysfunction by Ischemic Insults Through Akt Signaling Pathway. Toxicological sciences : an official journal of the Society of Toxicology, 2017 Dec 1;160(2):341-350	2017
Zhang J, Zhao P, Quan N, Wang L, Chen X, Cates C, Rousselle T, Li J, The endotoxemia cardiac dysfunction is attenuated by AMPK/mTOR signaling pathway regulating autophagy. Biochemical and biophysical research communications, 2017 Oct 21;492(3):520-527	2017
Zhang C, Sun W, Li J, Xiong B, Frye MD, Ding D, Salvi R, Kim MJ, Someya S, Hu BH, Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea. Neuroscience, 2017 Oct 11;361:179-191	2017
Quan N, Sun W, Wang L, Chen X, Bogan JS, Zhou X, Cates C, Liu Q, Zheng Y, Li J, Sestrin2 prevents age-related intolerance to ischemia and reperfusion injury by modulating substrate metabolism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017 Sep;31(9):4153-4167	2017
Yang H, Sun W, Quan N, Wang L, Chu D, Cates C, Liu Q, Zheng Y, Li J, Cardioprotective actions of Notch1 against myocardial infarction via LKB1-dependent AMPK signaling pathway. Biochemical pharmacology, 2016 May 15;108:47-57	2016
Liu Z, Chen JM, Huang H, Kuznicki M, Zheng S, Sun W, Quan N, Wang L, Yang H, Guo HM, Li J, Zhuang J, Zhu P, The protective effect of trimetazidine on myocardial ischemia/reperfusion injury through activating AMPK and ERK signaling pathway. Metabolism: clinical and experimental, 2016 Mar;65(3):122-30	2016
Sun W, Quan N, Wang L, Yang H, Chu D, Liu Q, Zhao X, Leng J, Li J, Cardiac-Specific Deletion of the Pdha1 Gene Sensitizes Heart to Toxicological Actions of Ischemic Stress. Toxicological sciences : an official journal of the Society of Toxicology, 2016 May;151(1):193-203	2016
Wang J, Ma Y, Sachs F, Li J, Suchyna TM, GsMTx4-D is a cardioprotectant against myocardial infarction during ischemia and reperfusion. Journal of molecular and cellular cardiology, 2016 Sep;98:83-94	2016
Dungan CM, Li J, Williamson DL, Caloric Restriction Normalizes Obesity-Induced Alterations on Regulators of Skeletal Muscle Growth Signaling. Lipids, 2016 Aug;51(8):905-12	2016
Chen S, Wang Z, Xu B, Mi X, Sun W, Quan N, Wang L, Chen X, Liu Q, Zheng Y, Leng J, Li J, The Modulation of Cardiac Contractile Function by the Pharmacological and Toxicological Effects of Urocortin2. Toxicological sciences : an official journal of the Society of Toxicology, 2015 Dec;148(2):581-93	2015
Ma Y, Li J, Metabolic shifts during aging and pathology. Comprehensive Physiology, 2015 Apr;5(2):667-86	2015
Morrison A, Chen L, Wang J, Zhang M, Yang H, Ma Y, Budanov A, Lee JH, Karin M, Li J, Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015 Feb;29(2):408-17	2015
Ma Y, Wang J, Gao J, Yang H, Wang Y, Manithody C, Li J, Rezaie AR, Antithrombin up-regulates AMP-activated protein kinase signalling during myocardial ischaemia/reperfusion injury. Thrombosis and haemostasis, 2015 Feb;113(2):338-49	2015
Sun W, Fu Q, Zhang C, Manohar S, Kumaraguru A, Li J, Loudness perception affected by early age hearing loss. Hearing research, 2014 Jul;313:18-25	2014
Chen S, Zhu P, Guo HM, Solis RS, Wang Y, Ma Y, Wang J, Gao J, Chen JM, Ge Y, Zhuang J, Li J, Alpha1 catalytic subunit of AMPK modulates contractile function of cardiomyocytes through phosphorylation of troponin I. Life sciences, 2014 Mar 11;98(2):75-82	2014
Li J, Qi D, Cheng H, Hu X, Miller EJ, Wu X, Russell KS, Mikush N, Zhang J, Xiao L, Sherwin RS, Young LH, Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart. Proceedings of the National Academy of Sciences of the United States of America, 2013 Oct 1;110(40):16133-8	2013
Wang J, Tong C, Yan X, Yeung E, Gandavadi S, Hare AA, Du X, Chen Y, Xiong H, Ma C, Leng L, Young LH, Jorgensen WL, Li J, Bucala R, Limiting cardiac ischemic injury by pharmacological augmentation of macrophage migration inhibitory factor-AMP-activated protein kinase signal transduction. Circulation, 2013 Jul 16;128(3):225-36	2013
Tong C, Morrison A, Mattison S, Qian S, Bryniarski M, Rankin B, Wang J, Thomas DP, Li J, Impaired SIRT1 nucleocytoplasmic shuttling in the senescent heart during ischemic stress. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013 Nov;27(11):4332-42	2013
Sun L, Liu Y, Lin S, Shang J, Liu J, Li J, Yuan S, Zhang L, Early growth response gene-1 and hypoxia-inducible factor-1α affect tumor metastasis via regulation of tissue factor. Acta oncologica (Stockholm, Sweden), 2013 May;52(4):842-51	2013
Yeung ED, Morrison A, Plumeri D, Wang J, Tong C, Yan X, Li J, Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway. The Prostate, 2012 Feb 1;72(2):165-72	2012
Costa R, Morrison A, Wang J, Manithody C, Li J, Rezaie AR, Activated protein C modulates cardiac metabolism and augments autophagy in the ischemic heart. Journal of thrombosis and haemostasis : JTH, 2012 Sep;10(9):1736-44	2012
Sun W, Manohar S, Jayaram A, Kumaraguru A, Fu Q, Li J, Allman B, Early age conductive hearing loss causes audiogenic seizure and hyperacusis behavior. Hearing research, 2011 Dec;282(1-2):178-83	2011
Morrison A, Yan X, Tong C, Li J, Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice. American journal of physiology. Heart and circulatory physiology, 2011 Sep;301(3):H895-902	2011
Morrison A, Li J, PPAR-γ and AMPK--advantageous targets for myocardial ischemia/reperfusion therapy. Biochemical pharmacology, 2011 Aug 1;82(3):195-200	2011
Kim AS, Miller EJ, Wright TM, Li J, Qi D, Atsina K, Zaha V, Sakamoto K, Young LH, A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. Journal of molecular and cellular cardiology, 2011 Jul;51(1):24-32	2011
Wang J, Yang L, Rezaie AR, Li J, Activated protein C protects against myocardial ischemic/reperfusion injury through AMP-activated protein kinase signaling. Journal of thrombosis and haemostasis : JTH, 2011 Jul;9(7):1308-17	2011
Yao HR, Liu J, Plumeri D, Cao YB, He T, Lin L, Li Y, Jiang YY, Li J, Shang J, Lipotoxicity in HepG2 cells triggered by free fatty acids. American journal of translational research, 2011 May 15;3(3):284-91	2011
Li Y, Xu S, Giles A, Nakamura K, Lee JW, Hou X, Donmez G, Li J, Luo Z, Walsh K, Guarente L, Zang M, Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011 May;25(5):1664-79	2011
Yan X, Yan X, Morrison A, Han T, Chen Q, Li J, Wang J, Fluoride induces apoptosis and alters collagen I expression in rat osteoblasts. Toxicology letters, 2011 Feb 5;200(3):133-8	2011
Tong C, Morrison A, Yan X, Zhao P, Yeung ED, Wang J, Xie J, Li J, Macrophage migration inhibitory factor deficiency augments cardiac dysfunction in Type 1 diabetic murine cardiomyocytes. Journal of diabetes, 2010 Dec;2(4):267-74	2010
Wang J, Ma H, Tong C, Zhang H, Lawlis GB, Li Y, Zang M, Ren J, Nijland MJ, Ford SP, Nathanielsz PW, Li J, Overnutrition and maternal obesity in sheep pregnancy alter the JNK-IRS-1 signaling cascades and cardiac function in the fetal heart. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010 Jun;24(6):2066-76	2010
Turdi S, Fan X, Li J, Zhao J, Huff AF, Du M, Ren J, AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction. Aging cell, 2010 Aug;9(4):592-606	2010
Kandadi MR, Rajanna PK, Unnikrishnan MK, Boddu SP, Hua Y, Li J, Du M, Ren J, Sreejayan N, 2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities. Biochemical pharmacology, 2010 Feb 15;79(4):623-31	2010
Zhang X, Yeung ED, Wang J, Panzhinskiy EE, Tong C, Li W, Li J, Isoliquiritigenin, a natural anti-oxidant, selectively inhibits the proliferation of prostate cancer cells. Clinical and experimental pharmacology & physiology, 2010 Aug;37(8):841-7	2010
Ma H, Wang J, Thomas DP, Tong C, Leng L, Wang W, Merk M, Zierow S, Bernhagen J, Ren J, Bucala R, Li J, Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart. Circulation, 2010 Jul 20;122(3):282-92	2010
Wang J, Li J, Activated protein C: a potential cardioprotective factor against ischemic injury during ischemia/reperfusion. American journal of translational research, 2009 Jul 15;1(4):381-92	2009
Wang J, Ma H, Zhang X, He L, Wu J, Gao X, Ren J, Li J, A novel AMPK activator from Chinese herb medicine and ischemia phosphorylate the cardiac transcription factor FOXO3. International journal of physiology, pathophysiology and pharmacology, 2009 Mar 25;1(2):116-126	2009
Li D, Wang Z, Chen H, Wang J, Zheng Q, Shang J, Li J, Isoliquiritigenin induces monocytic differentiation of HL-60 cells. Free radical biology & medicine, 2009 Mar 15;46(6):731-6	2009
Zhao P, Wang J, He L, Ma H, Zhang X, Zhu X, Dolence EK, Ren J, Li J, Deficiency in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia. Journal of cellular and molecular medicine, 2009 Aug;13(8A):1513-25	2009
Zhao P, Wang J, Ma H, Xiao Y, He L, Tong C, Wang Z, Zheng Q, Dolence EK, Nair S, Ren J, Li J, A newly synthetic chromium complex-chromium (D-phenylalanine)3 activates AMP-activated protein kinase and stimulates glucose transport. Biochemical pharmacology, 2009 Mar 15;77(6):1002-10	2009
Li Q, Ceylan-Isik AF, Li J, Ren J, Deficiency of insulin-like growth factor 1 reduces sensitivity to aging-associated cardiomyocyte dysfunction. Rejuvenation research, 2008 Aug;11(4):725-33	2008
Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH, Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature, 2008 Jan 31;451(7178):578-82	2008
Miller EJ, Li J, Sinusas KM, Holman GD, Young LH, Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart. American journal of physiology. Endocrinology and metabolism, 2007 Jun;292(6):E1922-8	2007
Reznick RM, Zong H, Li J, Morino K, Moore IK, Yu HJ, Liu ZX, Dong J, Mustard KJ, Hawley SA, Befroy D, Pypaert M, Hardie DG, Young LH, Shulman GI, Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell metabolism, 2007 Feb;5(2):151-6	2007
Zhang L, Li J, Young LH, Caplan MJ, AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proceedings of the National Academy of Sciences of the United States of America, 2006 Nov 14;103(46):17272-7	2006
Shi X, Leng L, Wang T, Wang W, Du X, Li J, McDonald C, Chen Z, Murphy JW, Lolis E, Noble P, Knudson W, Bucala R, CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity, 2006 Oct;25(4):595-606	2006
Li J, Coven DL, Miller EJ, Hu X, Young ME, Carling D, Sinusas AJ, Young LH, Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart. American journal of physiology. Heart and circulatory physiology, 2006 Oct;291(4):H1927-34	2006
Li J, Miller EJ, Ninomiya-Tsuji J, Russell RR 3rd, Young LH, AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart. Circulation research, 2005 Oct 28;97(9):872-9	2005
Young LH, Li J, Baron SJ, Russell RR, AMP-activated protein kinase: a key stress signaling pathway in the heart. Trends in cardiovascular medicine, 2005 Apr;15(3):110-8	2005
Baron SJ, Li J, Russell RR 3rd, Neumann D, Miller EJ, Tuerk R, Wallimann T, Hurley RL, Witters LA, Young LH, Dual mechanisms regulating AMPK kinase action in the ischemic heart. Circulation research, 2005 Feb 18;96(3):337-45	2005
Russell RR 3rd, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, Mu J, Birnbaum MJ, Young LH, AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. The Journal of clinical investigation, 2004 Aug;114(4):495-503	2004
Li J, Hu X, Selvakumar P, Russell RR 3rd, Cushman SW, Holman GD, Young LH, Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle. American journal of physiology. Endocrinology and metabolism, 2004 Nov;287(5):E834-41	2004
Li J, Holbrook NJ, Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress. Experimental gerontology, 2004 May;39(5):735-44	2004
Li J, Holbrook NJ, Common mechanisms for declines in oxidative stress tolerance and proliferation with aging. Free radical biology & medicine, 2003 Aug 1;35(3):292-9	2003
Li J, Gorospe M, Barnes J, Liu Y, Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts. The Journal of biological chemistry, 2003 Apr 11;278(15):13183-91	2003
Ikeyama S, Wang XT, Li J, Podlutsky A, Martindale JL, Kokkonen G, van Huizen R, Gorospe M, Holbrook NJ, Expression of the pro-apoptotic gene gadd153/chop is elevated in liver with aging and sensitizes cells to oxidant injury. The Journal of biological chemistry, 2003 May 9;278(19):16726-31	2003
Cui K, Li J, Xing G, Li JL, Wang L and Wang Y. Effect of hydrogen peroxide on synthesis of proteins during somatic embryogenesis in Lycium barbarum Plant Cell, Tissue and Organ Culture 2002; 68: 187-193.	2002
Chen P, Li J, Barnes J, Kokkonen GC, Lee JC, Liu Y, Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. Journal of immunology (Baltimore, Md. : 1950), 2002 Dec 1;169(11):6408-16	2002
Li J, Chen P, Sinogeeva N, Gorospe M, Wersto RP, Chrest FJ, Barnes J, Liu Y, Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells. The Journal of biological chemistry, 2002 Dec 20;277(51):49504-10	2002
Hutter D, Chen P, Li J, Barnes J, Liu Y, The carboxyl-terminal domains of MKP-1 and MKP-2 have inhibitory effects on their phosphatase activity. Molecular and cellular biochemistry, 2002 Apr;233(1-2):107-17	2002
Chen RC, Su JH, Yang SM, Li J, Wang TJ, Zhou H, Effect of isoverbascoside, a phenylpropanoid glycoside antioxidant, on proliferation and differentiation of human gastric cancer cell. Acta pharmacologica Sinica, 2002 Nov;23(11):997-1001	2002
Li J, Gorospe M, Hutter D, Barnes J, Keyse SM, Liu Y, Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. Molecular and cellular biology, 2001 Dec;21(23):8213-24	2001
Xing G, Cui K, Ji L, Wang Y, Li Z, Water stress and accumulation of beta-N-oxalyl-L-alpha,beta-diaminopropionic acid in grass pea (Lathyrus sativus). Journal of agricultural and food chemistry, 2001 Jan;49(1):216-20	2001
Li J, Chen JJ, Gao XP, Zhou J, Luo DX and Li BG The inducing role of antioxidant quercetin in apoptosis of human leukemia HL-60 cells Chin J Hematol 2000; 21: 319-320	2000
Li J, Chen JJ and Wang RH Prevention and mechanism of H2O2-induced apoptosis by nerve growth factor in glioma cell line A-172 Chin J Cancer 2000; 19:404-408	2000
Huang C, Li J, Zheng R, Cui K, Hydrogen peroxide-induced apoptosis in human hepatoma cells is mediated by CD95(APO-1/Fas) receptor/ligand system and may involve activation of wild-type p53. Molecular biology reports, 2000 Mar;27(1):1-11	2000
Li J, Chen JJ, Zhang F, Zhang C, Ebselen protection against hydrogen peroxide-induced cytotoxicity and DNA damage in HL-60 cells. Acta pharmacologica Sinica, 2000 May;21(5):455-9	2000
Wang Z, Li J, Zheng R, Wang B, Jia Z In vitro antitumor activities of pencyclic triterpenoid glycosyl esters from Rubus pileatus Chinese Pharmaceutical J 1999; 34:164-164.	1999
Li J, Chen JJ, Gao XP and Li BG. TNF-alpha induces apoptosis of human hepatoma cell SMMC-7721 and regulates the expression of Bcl-2 Chinese J Cancer Biotherapy 1999; 6:194-195.	1999
Li J, Chen JJ, Ju Y, Jia ZJ and Zheng RL. Antitumor activities of natural stenine Natural Products Res & Dev 1999; 11: 14-17.	1999
Li JF, Li J, Liao X, Gao QX and Li DH Photosensitization of sulfonated aluminum phthalocyanine (AIPCS) on human hepatoma SMMC-7721 cell and its mechanism Tumour 1998; 18:262-264.	1998
Li J, Zheng Y, Zhou H, Su B, Zheng R, Differentiation of human gastric adenocarcinoma cell line MGc80-3 induced by verbascoside. Planta medica, 1997 Dec;63(6):499-502	1997
Li J, Ge RC, Zheng RL, Liu ZM, Jia ZJ, Antioxidative and chelating activities of phenylpropanoid glycosides from Pedicularis striata. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997 Jan;18(1):77-80	1997
Li J, Zheng Y, Zheng RL and Jia ZJ Antitumor activities of natural diene compounds Cancer Res. On Prevention and Treatment 1995; 22: 271-273.	1995
Li J, Zheng Y, Zheng RL, Liu ZM and Jia ZJ Antitumor effects of phenylpropanoid glycosides Chinese Pharmac J 1995; 30:269-270.	1995
Li J, Wang XX and Zheng RL Effect of extracts of sea buckthron on metabolism of DNA and protein of tumor cells and cAMP level of plasma in vitro J. Xiamen Univ. (Natural Sci) 1994; 33:887-890.	1994
Li J, Wang PF, Zheng R, Liu ZM, Jia Z, Protection of phenylpropanoid glycosides from Pedicularis against oxidative hemolysis in vitro. Planta medica, 1993 Aug;59(4):315-7	1993
Zheng RL, Wang PF, Li J, Liu ZM, Jia ZJ, Inhibition of the autoxidation of linoleic acid by phenylpropanoid glycosides from Pedicularis in micelles. Chemistry and physics of lipids, 1993 Jun;65(2):151-4	1993
Li J and Zheng RL Degradation of glutamic acid induced by ferrous salt and related to free radicals Progress in Biochem & Biophys. 1992; 19:473-474.	1992
Li J, Zheng RL, Liu ZM, Jia ZJ, Scavenging effects of phenylpropanoid glycosides on superoxide and its antioxidation effect. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992 Sep;13(5):427-30	1992
Zhang X, Zhu P, Zhang X, Ma Y, Li W, Chen JM, Guo HM, Bucala R, Zhuang J, Li J, Natural antioxidant-isoliquiritigenin ameliorates contractile dysfunction of hypoxic cardiomyocytes via AMPK signaling pathway. Mediators of inflammation, 2013;2013:390890
Liu J, Li J, Li WJ, Wang CM, The role of uncoupling proteins in diabetes mellitus. Journal of diabetes research, 2013;2013:585897
Cui M, Yu H, Wang J, Gao J, Li J, Chronic caloric restriction and exercise improve metabolic conditions of dietary-induced obese mice in autophagy correlated manner without involving AMPK. Journal of diabetes research, 2013;2013:852754
Li J, Huang CY, Zheng RL, Cui KR, Li JF, Hydrogen peroxide induces apoptosis in human hepatoma cells and alters cell redox status. Cell biology international, 2000;24(1):9-23
Ren JG, Zheng RL, Shi YM, Gong B, Li JF, Apoptosis, redifferentiation and arresting proliferation simultaneously triggered by oxidative stress in human hepatoma cells. Cell biology international, 1998;22(1):41-9
Zhang M, Wang CM, Li J, Meng ZJ, Wei SN, Li J, Bucala R, Li YL, Chen L, Berberine protects against palmitate-induced endothelial dysfunction: involvements of upregulation of AMPK and eNOS and downregulation of NOX4. Mediators of inflammation, 2013;2013:260464
Li J, Zheng R, Li J, Wang Z, Mechanisms of the induction of apoptosis in human hepatoma cells by tumour necrosis factor-alpha. Cell biology international, 2001;25(12):1213-9
Zoungrana LI, Didik S, Wang H, Slotabec L, Li J, Activated protein C in epilepsy pathophysiology. Frontiers in neuroscience, 2023;17:1251017
Murphy J, Le TNV, Fedorova J, Yang Y, Krause-Hauch M, Davitt K, Zoungrana LI, Fatmi MK, Lesnefsky EJ, Li J, Ren D, The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease. Frontiers in cardiovascular medicine, 2022;9:850538
Review Article
Goodman M, Liu Z, Zhu P, Li J AMPK activators as a drug for diabetes, cancer and cardiovascular disease Pharmaceutical Regulatory Affairs 2014; 3: 1000118.	2014
Zheng R, Wang C, Lin C, Shi Y, Li J, Zhao C, Zhang Q, Huang S, Mu P, Tan X. The earliest stage of carcinogenesis blocked by the fast repair of DNA transient damage Acta Biophy Sin 2012; 28: 185-199.	2012
Moussa A, Li J AMPK in myocardial infarction and diabetes: the yin/yang effect Acta Pharm Sin B 2012; 2:368-378.	2012
Zheng R, Jia Z, Li J, Huang S, Mu P, Zhang F, Wang C, Yuan C Fast repair of DNA radicals in the earliest stage of carcinogenesis suppress hallmarks of cancer RSC Adv 2011; 1:1610-1619.	2011
Miller EJ, Russell RR, Li J and Young LH AMPK-a pivotal rheostat in the control of cardiac metabolism Drug Discovery Today: Disease Mechanisms 2005; 2:93-100.	2005
Li J The dual role of nitric oxide in ischemic injury World Sciences & Technology Res Dev 1999; 21:23-26.	1999
Li J and Chen JJ Oxidative stress & neurodegenerative diseases Advances in Free Radical Life Sci 1999; 7:88-91.	1999
Li J and Chen JJ Redox signal transduction pathway via iron-sulfur clusters Advances in Free Radical Life Sci 1999; 7:77-81.	1999
Zhang Q, Li J and Wang LF Studies on antioxidative, antitumor activity and effect on T,B cells proliferation of copper (II) complex with 8-acetyl-4-methyl umbelliferone Advances in Free Radical Life Sci 1997; 5:60-64.	1997
Li J, Chen FY and Zheng RL Oxidative stress is a signal mechanism of apoptosis Advances in Free Radical Life Sci 1997; 5:14-19.	1997
Li JF, Li J and Zheng RL Measurement of EPR signal and protein thiols in lesions of human uterine cervix Advances in Free Radical Life Sci 1997; 5:97-100.	1997
Li J and Zheng RL Reactive oxygen species (ROS) induce apoptosis Chinese J. Cell Biology 1997; 19: 115-119.	1997
Abstracts
Quan N, Rousselle T, Zheng Y, Li J. Sestrin2 suppresses age-related hypertrophy by inhibiting mTORC1 signaling pathway Circulation (supplement) 2017, 135:A12390	2017
Wang L, Luckett C, Cates C, Rousselle T, Li X, Li J. Cardiomyocyte SIRT1 deficiency alters cardiac substrate metabolism and sensitizes myocardium to ischemic insults Circulation (supplement) 2017, 135:A15686	2017
Guo Z, Rousselle T, Luckett C, Cates C, Li J Caloric restriction increases the resistance of aged heart to myocardial ischemia/reperfusion injury via modulating AMPK-SIRT1 signaling pathway Circulation (supplement) 2017, 135: A20703	2017
Bi Y, Luckett C, Lu S, Li J Aspirin protects heart against ischemia-reperfusion injury via LKB1-Sestrin2-AMPK signaling cascade Circulation (supplement) 2017, 135: A15274	2017
Quan N, Cates C, Rousselle T, Li J Sestrin2 suppresses age-related hypertrophy by inhibiting mTORC1 signaling pathway Hypertension (supplement)	2017
Li J, Ma Y, Bogan J. A Tether Containing a UBX Domain (TUG) mediates glucose transporter translocation in the ischemic heart Circulation Research (supplement) A158	2017
Wang L, Cates C, Li J. Cardiomyocyte specific SIRT1 deficiency alters glucose metabolism in response to ischemic insults Diabetes (supplement) A519	2017
Chu D, Rousselle T, Cates C, Li J Glucose oxidation by pyruvate dehydrogenase ameliorates cardiomyocytes contractility in response to hypoxic stress ATVB 2017	2017
Li J, Quan N, Cates C Sestrin2 modulates substrate metabolism and prevents age-related intolerance to ischemia and reperfusion injury FASEB J (supplement) 2017, 31:1069.10	2017
Quan N, Wang L, Chu D, Chen X, Cates C, Liu Q, Zheng Y, Li J Sestrin2 prevents age-related intolerance to ischemia and reperfusion injury via modulating substrate metabolism Circulation (supplement) 2016, 134: A11974	2016
Wang L, Quan N, Chu D, Chen X, Zhao X, Li J Cardiomyocyte specific deletion of Sirt1 gene alters substrate metabolism and sensitizes myocardium to ischemia and reperfusion injury Circulation (supplement) 2016, 134: A12050	2016
Wang J, Ma Y, Sachs F, Suchyna T, Li J. GsMTx4-D is a cardioprotectant against myocardial infarction during ischemia and reperfusion Circulation (supplement) 2016, 134: A11804	2016
Chen X, Quan N, Wang L, Chu D, Zhao P, Xue M, Bi Y, Cates C, Li J. A potent and selective covalent inhibitor of JNK protects heart from both ischemia/reperfusion- and hypertension-induced heart failure Circulation (supplement) 2016, 134: A11919	2016
Wang J, Quan N, Wang L, Chen X, Chu D, Rezaie A, Li J Inactivation of AMP-activated protein kinase sensitizes heart to pressure overload-induced hypertrophy Circulation Supplement) 2016, 134: A12019	2016
Mohsin A, Chen Q, Quan N, Maceyka M, Samidurai A, Thompson J, Hu Y, Li J, Lesnefsky EJ. Cardioprotection during early reperfusion via Complex I inhibition by Metformin Circulation (Supplement) 2016, 134: A19919	2016
Sun W, Quan N, Wang L, Cates C, Li J The deficiency of pyruvate dehydrogenase in the heart alters cardiac glucose oxidation and sensitizes heart to ischemic insults Diabetes (supplement) A 479 (76th ADA Scientific Sessions, June 10-14, 2016, New Orleans)	2016
Wang J, Quan N, Wang L, Cates C, Li J AMP-activated protein kinase mediates pressure overload-induced hypertrophy Hypertension	2016
Wang J, Quan N, Wang L, Sun W, Cates C, Chu D, Chen X, Rezaie A, Li J Cardiac deficiency of AMPK exacerbates heart hypertrophy by pressure overload ATVB 2016 (2016 ATVB/PVD Scientific Sessions, May 5-7, 2016, Nashville)	2016
Quan N, Sun W, Wang L, Chu D, Chen X, Cates C, Li J Impaired cardiac Sestrin2 signaling in response to ischemic insults with aging ATVB 2016 (2016 ATVB/PVD Scientific Sessions, May 5-7, 2016, Nashville)	2016
Ma Y, Sun W, Quan N, Wang L, Chen X, Bogan J, Li J A novel anchor protein TUG mediates GLUT4 translocation by AMP-activated protein kinase in the ischemic heart Circulation 131 (supplement) A13103, 2015 (2015 AHA Scientific Sessions, Nov. 7-11, 2015, Orlando)	2015
Sun W, Liu Q, Leng J, Zheng Y, Li J The cardiac deficiency of pyruvate dehydrogenase complex alters cardiac glucose oxidation and sensitizes heart to ischemic insults Diabetes (supplement) (75th ADA Scientific Sessions, June 4-9, 2015 Boston)	2015
Ma Y, Wang J, Techiryan G, Sun W, Wang Y, Li J The cardioprotective effect of Dexamethasone through activation of RISK pathway FASEB J 29 (supplement) 1026.6 (Experimental Biology, Mar.28-April 1, 2015, Boston)	2015
Ma Y, Wang J, Wang Y, Bogan J, Li J TUG mediates GLUT4 translocation by AMP-activated protein kinase in the heart FASEB J 29 (supplement) 1026.7 (Experimental Biology, Mar.28-April 1, 2015, Boston)	2015
Wang J, Sun W, Ma Y, Techiryan G, Zhang T, Zhang J, Li J A potent and selective covalent inhibitor of JNK protects heart from both ischemia/reperfusion- and hypertension-induced heart failure Circulation 130 (supplement): A13262, 2014 (2014 AHA Scientific Sessions, Nov., 2014, Chicago)	2014
Ma Y, Wang J, Gao J‡, Yang H, Sun W, Chen X, Wang Y, Rezaie AR, Li J AMP-activated protein kinase signaling mediates the cardioprotective effect of antithrombin against myocardial ischemia and reperfusion injury Circulation 130 (supplement): A11738, 2014 (2014 AHA Scientific Sessions, Nov., 2014, Chicago)	2014
Wang J, Sun W, Techiryan G, Sachs F, Suchyna T, Li J GsMTx4-D is a cardioprotectant against myocardial infarction during ischemia and reperfusion Circulation 130 (supplement): A12292, 2014 (2014 AHA Scientific Sessions, Nov., 2014, Chicago)	2014
Yang H, Sun W, Ma Y, Chen X, Techiryan G, Li J Activated Notch1 interacting with LKB1 reduces myocardial ischemic injury via modulating AMPK signaling pathway Circulation 130 (supplement): A12099, 2014 (2014 AHA Scientific Sessions, Nov., 2014, Chicago)	2014
Wang J, Ma Y, Sun W‡, Techiryan G, Wang Y, Li J Cardiac SIRT1 deficiency sensitizes myocardium to ischemia and reperfusion injury Circulation 130 (supplement): A13311, 2014 (2014 AHA Scientific Sessions, Nov., 2014, Chicago)	2014
Liu Z, Ma Y, Kuznicki M, Chen X, Sun W, Zhu P, Li J The cardioprotection of Trimetazidine against ischemic injury is mediated by AMPK and ERK signaling pathways Circulation 130 (supplement): A12117, 2014 (2014 AHA Scientific Sessions, Nov., 2014, Chicago)	2014
Ma Y, Sun W, Yawson E, Techiryan G, Wang J, Liu Z, Yang H, Chen X, Wang Y, Bogan J, Li J TUG mediates GLUT4 translocation by AMP-activated protein kinase in the heart Circulation 130 (supplement): A12301, 2014 (2014 AHA Scientific Session, Nov., 2014, Chicago)	2014
Li J, Morrison A, Ma Y, Wang J, Liu Z, Budanov A, Lee JH, Karin M Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart Circulation Research 114 (supplement): A087, 2014 (2014 Basic Cardiovascular Sciences Scientific Sessions, July, Las Vegas)	2014
Li J, Wang J, Sachs F, Suchyna TM GsMTx4-D is a cardioprotectant against myocardial infarction during ischemia and reperfusion Circulation Research 114 (supplement): A341, 2014 (2014 Basic Cardiovascular Sciences Scientific Sessions, July, Las Vegas)	2014
Li J, Ma Y, Wang J, Yang H, Wang Y, Masnithody C, Rezaie A AMP-activated protein kinase signaling mediates the cardioprotective effect of antithrombin against myocardial ischemia and reperfusion injury Circulation Research 114 (supplement): A088, 2014 (2014 Basic Cardiovascular Sciences Scientific Sessions, July, Las Vegas)	2014
Ma Y, Wang J, Yang H, Rezaie A, Li J AMPK mediates glucose transporter translocation by Antithrombin in the ischemic heart Diabetes 63 (supplement): A127, 2014 (74th ADA Scientific Session, June 13-17, 2014, San Francisco)	2014
Morrison A, Ma Y, Wang L, Wang Y, Li J Sestrin2 is an essential regulator of cardiac AMPK signaling during ischemia Circulation 128 (supplement): A12324, 2013 (2013 AHA Scientific Session, Nov., 2013, Dallas)	2013
Li J, Wang J, Wang Y, Wang J, Gao J, Yawson E, Manithody C, Rezaie AR Antithrombin exerts a cardioprotective effect against myocardial ischemia/reperfusion injury through induction of prostacyclin and inhibition of NF-kB signaling Circulation Research 113 (supplement): A094, 2013 (2013 Basic Cardiovascular Sciences Scientific Sessions, July, Las Vegas)	2013
Wang J, Tong C, Jorgensen WL, Bucala R, Li J. Limiting cardiac ischemic injury by pharmacologic augmentation of translocation of glucose transporter Diabetes 62 (supplement 1):A1187, 2013. (73rd ADA Scientific Session, Chicago, June, 2013)	2013
Morrison-Nozik A, Tong C, Lee JH, Budanov AV, Karin M, Li J Sestrin2 is Cardioprotective against Ischemia/Reperfusion Injury by Promoting LKB1-Mediated AMPK Activation Experimental Biology 2013, April 2013, Boston, MA. FASEB J 27 (supplement): 652.9, 2013. (*Oral Presentation)	2013
Wang J, Yan X, Yang L, Rezaie AR, Li J. Antithrombin protects against cardiac ischemia/reperfusion injury via inhibiting the NF-kB signaling pathway Circulation 126 (supplement): A11204, 2012. (2012 AHA Scientific Session, Nov, 2012, Los Angeles)	2012
Tong C, Morrison A, Wang J, Thomas DP, Li J Impaired SIRT1 nucleocytoplasmic shuttling in the senescent heart during ischemic stress Circulation 126 (supplement): A11344, 2012. (2012 AHA Scientific Session, Nov, 2012, Los Angeles)	2012
Morrison A, Tong C, Lee JH, Karin M, Li J Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart Circulation 126 (supplement): A11766, 2012. (2012 AHA Scientific Session, Nov, 2012, Los Angeles)	2012
Yan X, Wang J, Li J Fluoride reduction of contractile heart function in response to ischemic stress Oral Presentation, 30th Conference of the International Society for Fluoride Research September 5-8, 2012, Szczecin, Poland	2012
Morrison A, Tong C, Lee JH, Karin M, Li J Sestrin2 mediates the LKB1-AMPK signaling cascade in the ischemic heart Circulation Research 111 (supplement): A93, 2012 (2012 Basic Cardiovascular Sciences Scientific Sessions, New Orleans)	2012
Costa R, Wang J, Yang L, Rezaie A, Li J Activated protein C imparts its cardioprotective effects through modulating glucose metabolism Diabetes 61 (supplement 1):A561, 2012. (72nd ADA Scientific Session, Philadelphia, June, 2012)	2012
Brown KD, Waggy ED, Peterson M, Du M, Sreejayan N, Li J, Thomas PD Gender disparity in cardiac AMPK activation in response to exhaustive exercise Am Coll Sports Med (ACSM’s 59th Annual Meeting and 3rd World Congress in Exercise is Medicine, May 29, 2012, San Francisco)	2012
Wang J, Yan X, Fu Q, Cui M, Yang L, Rezaie A, Li J Activated protein C protects against ischemic injury by activating AMPK signaling and regulating substrate metabolism Circulation 124 (supplement): A10639, 2011. (2011 AHA Scientific Session, Nov, 2011, Orlando)	2011
Morrison A, Yan X, Li J Acute rosiglitazone treatment is cardioprotective against ischemia/reperfusion injury by modulating AMPK, Akt, and JNK signaling in non-diabetic mice Circulation 124 (supplement): A9827, 2011. (2011 AHA Scientific Session, Nov, 2011, Orlando)	2011
Tong C, Morrison A, Thomas DP, Li J SIRT1 activation restores cardioprotection in the aged heart against ischemia/reperfusion injury Circulation 124 (supplement): A10153, 2011. (2011 AHA Scientific Session, Nov, 2011, Orlando)	2011
Tong C, Thomas DP, Wang J, Li J Impaired nucleocytoplasmic shuttling of SIRT1 in the senescent heart in response to ischemic stress Circulation 124 (supplement): A10395, 2011. (2011 AHA Scientific Session, Nov, 2011, Orlando)	2011
Morrison A, Tong C, Lee JH, Karin M, Li J Sestrin2 mediates the LKB1-AMPK signaling cascade in the ischemic heart Circulation 124 (supplement): A10070, 2011. (2011 AHA Scientific Session, Nov, 2011, Orlando)	2011
Wang J, Yan X, Yang L, Rezaie AR, Li J Antithrombin protects against cardiac ischemia/reperfusion injury via inhibiting the NF-kB pathway Circulation 124 (supplement): A10505, 2011. (2011 AHA Scientific Session, Nov, 2011, Orlando)	2011
Morrison A, Li J Acute rosiglitazone treatment activates cardioprotective signaling during ischemia/reperfusion in non-diabetic mice Circulation 122 (supplement): A21, 2010. (2010 AHA Scientific Session, Nov, 2010, Chicago)	2010
Wang J, Yan X, Yang L, Rezaie AR, Li J The cardioprotective effect of activated protein C is separate from its anticoagulant activity Circulation 122 (supplement): A13452, 2010 (2010 AHA Scientific Session, Nov, 2010, Chicago)	2010
Tong C, Yan X, Thomas DP, Li J Impaired nucleocytoplasmic shuttling and activity of SIRT1 in the senescent heart in response to ischemic stress Circulation 122 (supplement): A16057, 2010 (2010 AHA Scientific Session, Nov, 2010, Chicago)	2010
Wang J, Yan X, Yeung E, Gandavadi S, Hare AA, Du X, Leng L, Jorgensen WL, Li J, Bucala R Limiting cardiac ischemic injury by augmenting the MIF-AMPK signaling cascade with a novel class of MIF receptor agonists Circulation 122 (supplement): A15835, 2010 (2010 AHA Scientific Session, Nov, 2010, Chicago)	2010
Thomas DP, Waggy E, Armstrong C, Brown K, Wang J, Li J Exercise training enhances cardiac AMP-activated protein kinase signaling to both physiological and pathological stress 15th Annual ECSS-Congress, June 23-26, Antalya, Turkey, 2010	2010
Wang J, Tong C, Ford SP, Nathanielsz NW, Li J Overnourished obese sheep in pregnancy alters insulin signaling cascades and cardiac function in the fetal heart Diabetes 59 (supplement 1): A42-A42, 2010. (70th ADA Scientific Session, June, 2010, Orlando)	2010
Wang J, Tong C, Leng L, Merk M, Zierow S, Bernhagen J, Bucala R, Li J Impaired AMPK-mediated glucose transport and ischemic recovery in the senescent heart Diabetes 59 (supplement 1):A245-A245, 2010. (70th ADA Scientific Session, June, 2010, Orlando)	2010
Wang J, Ma H, Zhao P, Ren J, Ford SP, Nathanielsz PW, Li J. Impairment of JNK-IRS-1 signaling cascades and cardiac function in fetal heart during overnourished obese sheep pregnancy Circulation 120 (supplement): S491, 2009 (2009 AHA Scientific Session, Nov, 2009, Orlando)	2009
Wang J, Yang L, Rezaie AR, Li J Activated protein C protects heart against ischemia reperfusion injury via activating AMPK signaling pathway and decreasing inflammatory response Circulation 120 (supplement): S1489, 2009 (2009 AHA Scientific Session, Nov, 2009, Orlando)	2009
Ma H, Wang J, Thomas DP, Leng L, Wang W, Merk M, Zierow S, Bernhagen J, Ren J, Bucala R, Li J Role for reduced MIF secretion in attenuated AMPK activation and ischemic recovery in the senescent heart Circulation 120 (supplement): S1488, 2009 (2009 AHA Scientific Session, Nov, 2009, Orlando)	2009
Ma H, Wang J, Tong C, Leng L, Bucala R, Li J The role of extracellular signal-regulated kinase in cardioprotective effect of macrophage migration inhibitory factor Circulation 120 (supplement): S1463, 2009 (2009 AHA Scientific Session, Nov, 2009, Orlando)	2009
Zhang X, Wang J, Li W, Li J Natural antioxidant-isoliquiritigenin protects heart against ischemia-reperfusion injury via activation of cardioprotective signaling pathways Circulation 120 (supplement): S1445, 2009 (2009 AHA Scientific Session, Nov, 2009, Orlando)	2009
Li J Aging-associated dysregulation of glucose transport in the heart Chinese Journal of Diabetes Mellitus 1 (supplement):10, 2009 (2009 Annual Meeting of Chinese Diabetes Society, Zhengzhou, China, Nov, 2009)	2009
Tong C, Zhao P, Xiao X, He L, Wang J, Perez Z, Ren J, Li J Macrophage migration inhibitory factor deficiency augments cardiac dysfunction in type 1 diabetic murine cardiomyocytes Diabetes 58 (supplement 1):A759-A759, 2009. (69th ADA Scientific Session, New Orleans, June, 2009)	2009
Wang J, Ma H, Zhang H, Zhao P, Ren J, Ford SP, Nathanielsz PW, Li J Impairment of JNK-IRS-1 signaling cascades in maternal and fetal heart tissue during overnourished obese sheep pregnancy Reproductive Sciences 16: 109A, 2009.	2009
Waggy E, Wang J, Armstrong C, Ma H, Li J, Thomas DP Effects of endurance training on AMP-activated protein kinase activity in the heart Med Sci Sports Exerc 41:S215, 2009.	2009
Li J, Kim AS, Cheng H, Hu X, Miller EJ, Wu X, Xiao L, Young LH AMPK mediates the cardioprotective effect of urocortin Circulation 118 (supplement): S433, 2008.	2008
Zhao P, He L, Ma H, Li J, Wang J, Zhu X, Ren J, Li J Toll-like receptor 4-deficiency improves ischemic cardiomyocytes contractile dysfunction via augmentation of AMPK activation. Circulation 118 (supplement) S277, 2008.	2008
Wang J, Ma H, Ren J, Li J Ischemia and AMPK activator phosphorylate the cardiac transcription factor FOXO3 National IDeA Symposium of Biomedical Research Excellence (NISBRE), Washington DC, 2008	2008
Li J Aging-associated impairment in the activation of AMP-activated protein kinase in the ischemic heart The Gerontologist 48 (supplement): 185, 2008.	2008
Li J, Kim AS, Cheng H, Hu X, Miller EJ, Wu X, Sherwin RS, Xiao L, Young LH AMP-activated Protein Kinase Mediates the Cardioprotective Effects of Urocortin via Augment Glucose Transport during Myocardial Ischemia Diabetes 57 (supplement): A403-A404, 2008.	2008
Li J, Haynes NA, Geringer M, Wen L, Young LH, Li J Toll-like receptor 4-deficiency limits ischemic injury via up-regulation of AMPK and down-regulation of p38 MAPK Diabetes 57 (supplement): A426-A426, 2008.	2008
Zhao P, Xiao X, Kim AS, Leite MF, Xu J, Zhu X, Ren J, Li J c-Jun inhibits ER-stress through up-regulation of down syndrome critical region 1 (DSCR1)/Adapt78 Diabetes 57 (supplement): A759-A759, 2008.	2008
Zhao P, Xiao Y, Nair S, Ren J and Li J A Newly synthetic chromium complex –chromium (D-phenylalanine)3 stimulates glucose transport via activation of AMP-activated protein kinase Diabetes 57 (supplement): A533-A534, 2008.	2008
Li J Signaling pathways in the ischemic hearts Chinese Pharmacologist 25:22-24, 2008.	2008
Ma H, Wang J, Wu J, Zhao P, Li Q, Gao X, Ren J, Li J A novel AMPK activator from Chinese herb medicine and ischemia phosphorylate the cardiac transcription factor FOXO3 Chinese Pharmacologist 25:52-54, 2008.	2008
Zhao P, Su G, Hao E, Xiao X, Zhu X, Ma H, Ren J, Li J Radix astragali suppresses myocardial inflammation and improves cardiac function in autoimmune myocarditis rats Chinese Pharmacologist 25:60-62, 2008	2008
Ma H, Wang J, Lane E, Ren J, Li J Alterations in cardiac MIF-AMPK cascades in response to ischemic stress with aging National IDeA Symposium of Biomedical Research Excellence (NISBRE), Washington DC, 2008.	2008
Kim A, Li J, Hu J, Edelman AM and Young LH Ca2+/Calmodulin-dependent Kinase Kinase β (CaMKKβ) contributes to AMPK activation in the heart during hypoxia Circulation 116:II-34, 2007.	2007
Li J, Cheng HY, Hu J, Liao C, Miller EJ, Wu X, Sherwin RS and Young LH Urocortin stimulates glucose uptake in the hypoxic by activation of PKCε-AMPK pathway Diabetes 56 (supplement I): A312-A312, 2007.	2007
Li J, Chen HY, Hu J, Liao C, Miller EJ, Sherwin RS, Young LH Cardiac urocortin stimulates hypoxic glucose uptake through activation of AMP-activated protein kinase Circulation 114 (supplement): II-136-II-136, 2006.	2006
Li J, Miller EJ, Hu X, Young LH Aging-related impairment the activation of AMP-activated protein kinase in the ischemic rat heart Diabetes 55 (supplement I): A334-A334, 2006.	2006
Kim A, Li J, Edelman AM, Miller EJ, Young LH. Ca2+/Camodulin-dependent protein kinase b activates AMP-activated protein kinase in the heart Diabetes 55 (supplement I): A12-A12, 2006.	2006
Li J, Miller EJ, Hu X, Jun Ninomiya-Tsuji, Russell RR, Young LH AMPK activates p38 MAP kinase by increasing its recruitment to TAB1 in the ischemic heart Circulation 112 (supplement II): II-181-II-181, 2005.	2005
Miller EJ, Li J, Leng L, Hu X, Atsumi T, Ortiz DJ, Bucala R, Young LH Macrophage migration inhibitory factor in the ischemic heart: activation of AMP-activated protein kinase, stimulation of glucose transport, and prevention of cardiac dysfunction Circulation 112 (supplement II): II-35-II-35, 2005.	2005
Li J, Miller EJ, Hu X, Russell RR, Mu J, Birnbaum MJ, Young LH AMP-activated protein kinase activation of p38 MAP kinase in the ischemic heart Diabetes 54 (supplement I): A479-A479, 2005.	2005
Miller EJ, Li J, Holman GD, Young LH Cell surface transporter isolation in the perfused mouse heart Diabetes 54 (supplement I): A315-A315, 2005.	2005
Miller EJ, Li J, Russell RR, Mu J, Birnbaum MJ, Young LH AMP-activated protein kinase deficiency increase myocardial injury after severe ischemia/reperfusion Diabetes 54 (supplement I): A484-A484, 2005.	2005
Reznick RM, Moore IK, Morino K, Li J, Young LH, Shulman GI Aging-associated reduction in AMP-activated protein kinase activity: potential role in insulin resistance of the elderly Diabetes 54 (supplement I): A93-A93, 2005.	2005
Coven DL, Li J, Hu X, Miller EJ, Carling D, Hardie G, Sinusas AJ, Young LH Regulation of cardiac a- and g-AMPK subunit isoforms in the in vivo ischemic heart Circulation 110 (supplement III): III-277-III-278, 2004.	2004
Baron S, Li J, Neumann D, Hurley RL, Witters LA, Russell RR, Young LH Dual mechanisms of AMP-activated protein kinase regulation in the ischemic heart Circulation 110 (suppl. III): III-323-III-323, 2004.	2004
Liu Y, Li J, Lorenzini A, Sinogeeva N, Chen P, Gorospe M, Cristofalo VJ Constitutively active Raf induces growth arrest in WI-38 normal human lung fibroblasts: The effects of active Raf on chromosomal structure and gene expression profiles Pediatric Research 53: 275A-275A, 2003.	2003
Holbrook NJ, Ikeyama S, Li J, Kokkonen T Cellular response to oxidants: links to proliferation and alteration with aging Free Radical Biol. Med. 33: S60-S60, 2002.	2002
Li J, Gorospe M, Hutter D, Barnes J, Keyse SM, Li Y Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation/acetylation FASEB J 16(4): A168-A168 Part 1, 2002.	2002
Li J, Ikeyama S, Liu Y Histone H3 modification in response to epidermal growth factor and arsenite declines with age in primary rat hepatocytes FASEB J 15(4): A10-A10 Part 1, 2001.	2001
Book Chapter
Li J Reactive Oxygen Species in Cell Death and Differentiation In Zheng RL. (Eds) Free Radical Life Sciences. pp216-234. (Ho-Chi Book Publishing Company), 2013 1st edition.	2013
Miller EJ, Qi D, Li J, Young L MIF in Cardiovascular Disease The MIF Handbook. pp220-235, World Scientific Publishing Co. Pte. Ltd. 2012	2012
Li J Apoptosis Medical Molecular Biology. pp216-234. (Chinese Union Medical University Press), 2000 1st edition, 2005 2nd edition.	2005
Clinical Trial
Ji K, Wang X, Li J, Lu Q, Wang G, Xue Y, Zhang S, Qian L, Wu W, Zhu Y, Wang L, Liao L, Tang J, Macrophage migration inhibitory factor polymorphism is associated with susceptibility to inflammatory coronary heart disease. BioMed research international, 2015;2015:315174
Editorial
Xiao J, Li J, Cai L, Chakrabarti S, Li X, Cytokines and diabetes research. Journal of diabetes research, 2014;2014:920613

Presentations

National and International Invited Seminars/Lectures, AMPK Signaling in Cardiovascular Aging, University of Missouri, Columbia, MU	04/2024
National and International Invited Seminars/Lectures, MIF in Ischemic Heart Disease, the 35th MIT Virtual Seminar, Virtual	01/2024
National and International Invited Seminars/Lectures, Targeting AMPK for Cardiorenal Syndrome, the 63rd Annual Meeting of Southern Salts, Water, and Kidney Society, Lido Key, FL	12/2023
Regional Invited Seminars/Lectures, Activated Protein C Signaling in Aging, Seminar of Physiology, Jackson, MS	09/2023
Invited Symposia, Signal Transduction of Activated Protein C in Aging, Single Cell Genomics Symposium, Tampa, FL	08/2022
Regional Invited Seminars/Lectures, Activated Protein C and Vascular Health in Aging, Department of Pharmacology and Toxicology, Jackson, MS	06/2022
National and International Invited Seminars/Lectures, AMPK Signaling in Age-related Heart Failure, Augusta University, Augusta, GA	02/2022
National and International Invited Seminars/Lectures, Activated Protein C and Vascular Health in Aging, Loyola University, Chicago, IL	01/2022
National and International Invited Seminars/Lectures, Metabolic Regulation is a Strategy to Limit Ischemic Insults in Aging, UT Health San Antonio, San Antonio, TX	04/2019
National and International Invited Seminars/Lectures, Metabolic Regulation is a Strategy to Limit Ischemic Insults in Aging, Temple University Lewis Katz School of Medicine, Philadelphia	12/2018
National and International Invited Seminars/Lectures, The Metabolic Regulations Associated with Inflammatory Response during Ischemic Insults, The 12th Oriental Congress of Cardiology, Shanghai, China	06/2018
National and International Invited Seminars/Lectures, A New Drug Target for Cardiovascular Disease, Northwest Institute of Plateau Biology, Xining, China	05/2018
Invited Symposia, AMPK as a Metabolic Sensor Regulates Inflammatory Response during Ischemic Insults, Experimental Biology 2018, San Diego, CA	04/2018
National and International Invited Seminars/Lectures, A Novel Stress Inducible Protein Sestrin2, the 20th South China International Congress of Cardiology, Guangzhou, China	04/2018
Platform Presentations, Activated Protein C and Cardiac Inflammatory Response, Cardiovascular-Renal Research Center, UMMC	03/2018
National and International Invited Seminars/Lectures, Glucose Transporter Trafficking during Myocardial Ischemia in Aging, Loma Linda University, Loma Linda, CA	02/2018
National and International Invited Seminars/Lectures, Cardiac Sirtuin 1 Signaling Pathway in Aging, The 8th Chinese-American Diabetic Complication Forum, Ruian, China	11/2017
National and International Invited Seminars/Lectures, Glucose Metabolic Regulation in Ischemic Heart Disease, The 28th Great Wall International Congress of Cardiology, Beijing, China	10/2017
National and International Invited Seminars/Lectures, Cardiac Glucose Transporter Trafficking in Aging, University of Iowa, Iowa City, Iowa	09/2017
National and International Invited Seminars/Lectures, Impaired Cardiac Glucose Transporter Trafficking in Aging, The 5th International Biomedical Forum of West China, Shihezi, China	08/2017
National and International Invited Seminars/Lectures, Cardiac Sestrin2 Signaling in Aging, 2017 Basic Cardiovascular Sciences Scientific Sessions, Portland, Oregon	07/2017
National and International Invited Seminars/Lectures, Sestrin2 Signaling in the Ischemic Heart, the 4th Yangtze River International Congress of Cardiology, Chongqing, China	04/2017
National and International Invited Seminars/Lectures, Cardiac Glucose Transporter Trafficking, the 19th South CHina International Congress of Cardiology, Guangzhou, China	04/2017
National and International Invited Seminars/Lectures, AMPK Signaling in Myocardial Infarction and Heart Failure, The 2nd Beijing International Conference Targeting AMPK: basic research and drug discovery, Beijing, China	11/2016
Platform Presentations, AMP-activated Protein Kinase Mediates Pressure Overload-induced Hypertrophy, 2016 Hypertension Scientific Sessions, Orlando, FL	09/2016
National and International Invited Seminars/Lectures, The Regulation of Glucose Transporter Trafficking, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China	07/2016
National and International Invited Seminars/Lectures, Cardiac Glucose Transporter Trafficking in Aging, Perking University, Beijing, China	07/2016
National and International Invited Seminars/Lectures, The Regulation of Glucose Transporter Trafficking, the 7th Chinese-American Diabetic Complication Forum, Ruian, China	07/2016
Regional Invited Seminars/Lectures, A New Strategy of Drug Treatment for Angina Pectoris, Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS	05/2016
National and International Invited Seminars/Lectures, The Regulation of Glucose Transport in the Ischemic Heart, University of Oklahoma HSC, Oklahoma City, OU	05/2016
State/Local Invited Seminars/Lectures, Impaired AMP-activated Protein Kinase Signaling in Aging during Ischemia and Reperfusion, Organ Transplant/Ischemia-Reperfusion Research Group, Department of Surgery, University of Mississippi Medical Center, Jackson, MS	04/2016
National and International Invited Seminars/Lectures, The regulation of metabolic shift in myocardial infarction, the 18th South China International Congress of Cardiology, Guangzhou, China	04/2016
National and International Invited Seminars/Lectures, The regulation of cardiac glucose transporter trafficking, the 19th Scientific Meeting of the Chinese Diabetes Society, Suzhou, China	12/2015
National and International Invited Seminars/Lectures, The Regulation of Cardiac Glucose Transporter Trafficking, Soochow University, Suzhou, China	12/2015
National and International Invited Seminars/Lectures, The Regulation of Glucose Trafficking in Ischemic Heart, the 6th Chinese-American Diabetic Complication Forum, Ruian, China	11/2015
National and International Invited Seminars/Lectures, The Regulation of Glucose Transporter in Heart Failure, 2015 Yuying Forum International Conference on Translational Medicine, Wenzhou, China	10/2015
National and International Invited Seminars/Lectures, The regulation of glucose metabolism in cardiovascular diseases, the 26th Great Wall International Congress of Cardiology (GW-ICC), Beijing, China	10/2015
National and International Invited Seminars/Lectures, The Cardioprotection of Macrophage Migration Inhibitory Factor against Ischemic Injury, the 17th South China International Congress of Cardiology, Guangzhou, China	04/2015
National and International Invited Seminars/Lectures, AMP-activated Protein Kinase in the Aged Heart, Wayne State University, Detroit, MI	09/2014
National and International Invited Seminars/Lectures, Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart, 9th Xiangya International Diabetes and Immunology Forum, Changsha, China	04/2014
State/Local Invited Seminars/Lectures, AMPK in the Aged Heart, Division of Geriatrics, Department of Medicine, SUNY at Buffalo, Clinical Translational Research Center (CTRC), Buffalo, NY	12/2013
National and International Invited Seminars/Lectures, AMP-activated Protein Kinase in the Aged Heart, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China	11/2013
National and International Invited Seminars/Lectures, More Evidence to Show the Cardioprotection of AMPK in Age-related Disease, Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China	11/2013
National and International Invited Seminars/Lectures, AMP-activated Protein Kinase in the Ischemic Heart, University of Maryland, Baltimore, MD	06/2013
National and International Invited Seminars/Lectures, Mechanism of APC-cardioprotection against Ischemic Injury, Drug Discovery & Therapy World Congress 2013, Boston, MA	06/2013
National and International Invited Seminars/Lectures, AMP-activated Protein Kinase in the Ischemic Heart, Aab Cardiovascular Research Institute (CVRI), University of Rochester Medical Center, Rochester, NY	05/2013
National and International Invited Seminars/Lectures, Mechanism of APC-Mediated Cardioprotection against Ischemic Injury, The 1st Changchun Forum for Cardiovascular Diseases and Dietary Nutrition, Changchun, China	04/2013
National and International Invited Seminars/Lectures, Macrophage Migration Inhibitory Factor and Glucose Homeostasis, the 8th Xiangya International Diabetes Immunology Forum, Changsha, China	04/2013
National and International Invited Seminars/Lectures, Sestrin2 is Cardioprotective against Ischemia/reperfusion Injury by Promoting LKB1-mediated AMPK Activation, the 15th South China International Congress of Cardiology, Guangzhou, China	04/2013
National and International Invited Seminars/Lectures, Activated Protein C (APC)-a new peptide for ischemic heart disease, 3rd International Conference on Fibroblast Growth Factors, Wenzhou, China	12/2012
National and International Invited Seminars/Lectures, Glucose Transporter Regulation by Macrophage Migration Inhibitory Factor, 16th Scientific Meeting of the Chinese Diabetes Society (CDS), Chengdu, China	12/2012
National and International Invited Seminars/Lectures, Sestrin2 Promotes LKB1-Mediated AMPK Activation in the Ischemic Heart, 2012 FASEB Science Research Conferences: AMPK and Beyond: Biology, Disease Mechanisms and Therapeutic Opportunities, Pacific Grove, CA	10/2012
National and International Invited Seminars/Lectures, Melatonin-Mediated Cardioprotective Signaling in Ischemic Heart, The 1st International Chinese Symposium on Free Radical Research, Lanzhou, China	08/2012
National and International Invited Seminars/Lectures, Sestrin2 Mediates the LKB1-AMPK Signaling Cascade in the Ischemic Heart, Basic Cardiovascular Sciences 2012 Scientific Sessions: Frontiers in Cardiovascular Science and Novel Therapy, New Orleans, LA	07/2012
State/Local Invited Seminars/Lectures, Optimizing Cardiac Function in Aging via a Novel Signaling Pathway, Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY	04/2012
State/Local Invited Seminars/Lectures, Optimizing Cardiac Function via Modulating Energy Sensor AMPK, University at Buffalo-SUNY, Department of Exercise and Nutrition Sciences, School of Public Health and Health Professions, Buffalo, NY	03/2012
National and International Invited Seminars/Lectures, Optimizing Cardiac Function in Aging via a Novel Signaling Pathway, Tongji University, Shanghai, China	12/2011
National and International Invited Seminars/Lectures, New Strategy for the Treatment of Angina, Chongqing Medical University, Chongqing, China	11/2011
National and International Invited Seminars/Lectures, Optimizing Cardiac Function in Aging via Modulating Glucose Transport, 2nd Symposium of China-American Complication of Diabetes, Wenzhou, China	11/2011
National and International Invited Seminars/Lectures, Optimizing Cardiac Function in Aging via MIF Signaling, 2011 The Bridge Medical Summit, Boston, MA	11/2011
National and International Invited Seminars/Lectures, Melatonin-Mediated Cardioprotective Signaling in Ischemic Heart, FASEB Summer Research Conference, Aspen Snowmass, CO	06/2011
National and International Invited Seminars/Lectures, AMPK: A Novel Target for Ischemic Heart Disease, Fourth Military Medical University, Xi'an, China	04/2011
National and International Invited Seminars/Lectures, AMPK: A Novel Target for Ischemic Heart Disease, China Pharmaceutical University, Nanjing, China	04/2011
National and International Invited Seminars/Lectures, Alterations in the Cardiac AMPK Signaling Pathways with Aging, Saint Louis University School of Medicine, St. Louis, MO	11/2010
National and International Invited Seminars/Lectures, The Regulation of AMPK Signaling Pathway in the Ischemic Heart, Shanxi Normal University, Lifen, China	10/2010
National and International Invited Seminars/Lectures, AMPK: A Novel Target for Ischemic Heart Disease, Chongqing Medical University, Chongqing, China	10/2010
State/Local Invited Seminars/Lectures, The Role of Energy Sensor, AMPK, during Myocardial Ischemia and Ischemic Stroke, Grand Rounds Lecture, University at Buffalo-SUNY, Department of Neurosurgery, Buffalo, NY	10/2010
National and International Invited Seminars/Lectures, The Cardioprotective Effect of Activated Protein C is Separate from its Anticoagulant Activity, 8th Annual Scientific Sessions of Society for Heart and Vascular Metabolism (SHVM), Kananaskis, Alberta, Canada	08/2010
National and International Invited Seminars/Lectures, Overnourished Obese Sheep in Pregnancy Alters Insulin Signaling Cascades and Cardiac Function in the Fetal Heart, 70th Scientific Session of American Diabetes Association, Orlando, FL	06/2010
National and International Invited Seminars/Lectures, Exercise Training Enhances Cardiac AMP-activated Protein Kinase (AMPK) Signaling to Both Physiological and Pathological Stress, 15th Annual Congress of the European College of Sport Science (ECSS), Antalya, Turkey	06/2010
National and International Invited Seminars/Lectures, Regulation of Signaling Pathways in the Heart, Lanzhou University, Lanzhou, China	04/2010
National and International Invited Seminars/Lectures, Maternal Obesity and Fetal Health, Shihezi University, Shihezi, China	04/2010
National and International Invited Seminars/Lectures, Aging-Associated Dysregulation of Glucose Transport in the Heart, 13th Scientific Session of Chinese Diabetes Society, Zhengzhou, China	11/2009
State/Local Invited Seminars/Lectures, Impaired Macrophage Migration Inhibitory Factor (MIF)-AMPK Cascades and Ischemic Recovery in the Senescent Heart, University at Buffalo-SUNY, Division of Cardiology, Buffalo, NY	10/2009
National and International Invited Seminars/Lectures, Aging-Associated Reduction in Ischemic AMPK Activation, the Whitaker Cardiovascular Center, Boston University, Boston, MA	04/2009
National and International Invited Seminars/Lectures, Aging-associated impairment in the activation of AMP-activated protein kinase in the ischemic heart, 61st Annual Scientific Meeting of Gerontological Society of America, Washington DC, MD	11/2008
National and International Invited Seminars/Lectures, AMPK mediates the cardioprotection effect of urocortin during ischemia, 2008 AHA Scientific Session, New Orleans, LA	11/2008
National and International Invited Seminars/Lectures, AMP-activated Protein Kinase: A Novel Target for Protection against Ischemic Injury, University of Arkansas Medical School, Little Rock, AR	10/2008
State/Local Invited Seminars/Lectures, MKP-1 and AMPK: Targets for Inflammatory and Ischemic Heart Disease, The Keynote speaker of UW INBRE retreat, Yellowstone, WY	09/2008
National and International Invited Seminars/Lectures, Signaling Pathways in the Ischemic Hearts, The Symposium of Chinese Cardiovascular Pharmacology Society, Lanzhou, China	07/2008
National and International Invited Seminars/Lectures, The Signaling Mechanisms of the Cellular Stress Response, Institute of Lanzhou Modern Physics, the Chinese Academy of Sciences (CAS), Lanzhou, China	07/2008
National and International Invited Seminars/Lectures, MAPK and AMPK: Critical Mediators of the Cellular Stress Response, Lanzhou University, Lanzou, China	07/2008
National and International Invited Seminars/Lectures, MKP-1 and AMPK: Targets for Inflammatory and Ischemic Heart Diseases, Shihezi University, Shihezi, China	07/2008
National and International Invited Seminars/Lectures, MAPK and AMPK: Critical Mediators of the Cellular Stress Response, Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences (SIBS), the Chinese Academy of Sciences (CAS), Shanghai, China	07/2008
National and International Invited Seminars/Lectures, AMPK: Mediator of the Cardioprotective Effects of MIF and Urocortin, Uniformed Service University, Bethesda, MD	06/2008
National and International Invited Seminars/Lectures, The Cellular Fuel Gauge-AMPK in the Heart, Saint Louis University, St. Louis, MO	04/2008
State/Local Invited Seminars/Lectures, Regulation of AMP-activated Protein Kinase in the Ischemic Heart, Department of Molecular Biology, University of Wyoming, Laramie, WY	02/2008
National and International Invited Seminars/Lectures, The Molecular Mechanisms of Cardioprotective Action of the Natural Polyphenols, Yunnan Spirin Biotech. Co. Inc., Kunming, China	01/2008
National and International Invited Seminars/Lectures, AMPK and MAPK: Critical Mediators of the Cellular Stress Response, Sichuan University, Chengdu, China	01/2008
State/Local Invited Seminars/Lectures, AMPK Mediates the Cardioprotective Effect of Urocortin during Ischemia, C-CRAM Symposium, University of Wyoming, Laramie, WY	11/2007

Honors, Awards, and Recognition

Gold level for the Excellence in Research Awards, University of Mississippi Medical Center	2015
Young Investigator Award, The 16th South China International Congress of Cardiology	2014
Seed Award for Research, University of Wyoming	2009
Travel Award for AHA Scientific Sessions, University of Wyoming, College of Health Sciences	2008
Research Award, Center for Cardiovascular Research & Alternative Medicine	2008
Fellow (FAHA), American Heart Association	2008
Selected Participant, 16th Annual Summer Training Course in Experimental Aging Research/NIH	2008
New Investigator Award, University of Wyoming	2007
Travel Award for AHA Scientific Sessions, American Heart Association	2005
Fellow Award for Research Excellence, NIH	2000

Professional Membership and Service

Chinese American Diabetes Association, Officer, President/Elect/Past, President-Elect	2013 - 2015
Upstate New York Pharmacology Society, Officer, Other Officer	2012 - 2015
Heart Failure Society of America, Member	2011 - 2013
American Physiology Society, Member	2011 - Present
American Society for Pharmacology & Experimental Therapeutics, Member	2010 - 2015
Chinese American Diabetes Association, Officer, Treasurer	2009 - 2013
American Heart Association, Fellow, FAHA	2008 - Present
The Academy of Cardiovascular Research Excellence, Member	2008 - Present
The Gerontological Society of America, Member	2007 - 2011
American Diabetes Association, Member	2005 - Present
American Heart Association and American Stroke Association (AHA/ASA), Member	2003 - Present
American Society for Biochemistry and Molecular Biology, Member	2000 - 2007

Committee Service

MEDICAL CENTER-INSTITUTIONAL BIOSAFETY, Member	2023 - Present
MEDICAL CENTER-FACULTY SENATE, Member	2018 - 2019
T32 Mentoring Committee, Member	2016 - Present
SUNY Buffalo School of Medicine Income Fund Reimbursable (IFR) Policy Committee, Member	2013 - 2015
SCHOOL OF GRADUATE STUDIES IN THE HEALTH SCIENCES-GRADUATE COUNCIL, Member	2011 - 2015
SUNY Buffalo Space Planning Committee, Member	2010 - 2011
SUNY Buffalo Undergraduate Education Committee, Member	2009 - 2015
SCHOOL OF GRADUATE STUDIES IN THE HEALTH SCIENCES-GRADUATE PROGRAM REVIEW, Member	2009 - 2011
ADA Grant Review, Member	2009 - Present
Assessment Committee, University of Wyoming School of Pharmacy, Member	2008 - 2009
Safety Committee, University of Wyoming School of Pharmacy, Member	2008 - 2009
As a Junior Faculty member meet the accreditation team of the Liaison Committee on Medical Education (LCME), Member

Community Service

AHA Scientific Sessions, Moderator	11/2018 - 11/2018
2016 AHA Scientific Sessions, Poster Professor	11/2016 - 11/2016
Hypertension 2016 Scientific Sessions, Moderator	09/2016 - 09/2016
2015 AHA Scientific Sessions, Poster Professor	11/2015 - 11/2015
AHA Scientific Sessions, Abstract Reviewer	06/2015 - Present
Chinese American Diabetes Association (CADA), President	06/2015 - 10/2015
Chinese American Diabtes Association (CADA), President-Elect	06/2013 - 05/2015
Upstate New York Pharmacology Society (UNYPS, ASPET), Councilor	03/2012 - 06/2015
Chinese American Diabetes Association (CADA), Treasurer	06/2009 - 05/2013

Other Service

Intramural Research Support Program (Reviewer, Grant Proposal)	05/2018 - 07/2018
Pennsylvania Department of Health (Reviewer, Grant Proposal)	04/2018 - Present
Swiss National Science Foundation (Reviewer, Grant Proposal)	09/2017 - Present
Florida Department of Health Biomedical Research Program (Reviewer, Grant Proposal)	11/2016 - Present
NIH Cardiac Contractility, Hypertrophy, and Failure (CCHF) Study Section (Reviewer, Ad Hoc Reviewer)	10/2016 - Present
National Institute of Health (NIH) SAT Study Section (Reviewer, Ad Hoc Reviewer)	06/2016 - Present
U.S. Department of Veterans Affairs (VA) CARA Study Section (Reviewer, Ad Hoc Reviewer)	05/2016 - Present
American Heart Association (AHA) Strategically Focus Research Network-Heart Failure (Reviewer, Grant Proposal)	04/2016 - Present
National Institute of Health (NIH) Special Emphasis Panels ZDK1 GRB-7 (M1) 1, R13 Conference Grant Applications (Reviewer, Ad Hoc Reviewer)	06/2015 - Present
National Institute of Health (NIH) ASG Study Section (Reviewer, Ad Hoc Reviewer)	2015 - Present
U.S. Department of Defense (DoD) Peer Reviewed Medical Research Program, Discovery-Metabolic Disease (DIS-MD) (Reviewer, Ad Hoc Reviewer)	06/2014 - Present
National Institute of Health (NIH) Special Emphasis Panels Zrg1 BDCN-N02 M SEP, Cognition, Diabetic Neuropathy and Metabolomics (Reviewer, Ad Hoc Reviewer)	06/2014 - Present
U.S. Department of Defense (DoD) Peer Reviewed Medical Research Program, Pre-Metabolic Disease (DIS-MD-2) (Reviewer, Ad Hoc Reviewer)	2014 - Present
National Institute of Health (NIH) Special Emphasis Panels Zrg1 BDCN-L02 SEP (Reviewer, Ad Hoc Reviewer)	2014 - Present
BioMed Research International (Editor, Journal Editor)	2014 - 12/2015
PLoS ONE (Reviewer, Journal Article)	07/2013 - Present
Life Sciences (Editor, Associate Editor)	07/2013 - 06/2016
World Journal of Cardiology (Editorial Review Board Member)	07/2013 - Present
National Institute of Health (NIH) MIM Study Section (Reviewer, Ad Hoc Reviewer)	06/2013 - Present
University of Washington NIH Diabetes Research Center's Pilot and Feasibility Study Program (Reviewer, Grant Proposal)	2013 - 12/2013
Louisiana Board of Regents Support Fund (Reviewer, Grant Proposal)	2013 - 12/2014
Molecular Medicine (Reviewer, Journal Article)	2013 - Present
Journal of Diabetes Research (Editor, Journal Editor)	2013 - 12/2014
PLOS Neglected Tropical Diseases (Editor, Associate Editor)	2013 - 12/2014
J Cardiovascular Pharmacology (Reviewer, Journal Article)	07/2012 - Present
Circulation (Reviewer, Journal Article)	2012 - Present
Cardiovascular Tox (Reviewer, Journal Article)	2012 - Present
J Nutrition Biochem (Reviewer, Journal Article)	07/2011 - Present
Circulation Res (Reviewer, Journal Article)	07/2011 - Present
Current Angiogenesis (Editorial Review Board Member)	07/2011 - Present
Open Journal of Endocrine and Metabolic Diseases (Editorial Review Board Member)	07/2011 - Present
American Journal of Cardiovascular Disease (Editorial Review Board Member)	07/2011 - Present
J Endocrinology (Reviewer, Journal Article)	2011 - Present
Diabetes (Reiviewer, Journal Article)	2011 - Present
Biochem Pharmacol (Reviewer, Journal Article)	2011 - Present
Arthristis & Rheumatism (Reviewer, Journal Article)	2011 - Present
PLoS Biology (Reviewer, Journal Article)	07/2010 - Present
Int'l Conference on Bioinformatics and Biomedical Engineering (Reviewer, Journal Article)	07/2010 - Present
Apoptosis (Reviewer, Journal Article)	07/2010 - Present
J Diabetes Complicat (Reviewer, Journal Article)	2010 - Present
Gynecologic Oncology (Reviewer, Journal Article)	2010 - Present
Diabetologia (Reviewer, Journal Article)	2010 - Present
Cancer Informatic (Reviewer, Journal Article)	2010 - Present
Biochim Biophys Acta (Reviewer, Journal Article)	2010 - Present
Arch Immunol Ther Ex (Reviewer, Journal Article)	2010 - Present
Am J Physiol-Cell Physiology (Reviewer, Journal Article)	2010 - Present
American Journal of Translational Research (Editorial Review Board Member)	06/2009 - 10/2015
American Diabetes Association (ADA) , Research Grant Review Committee (Reviewer, Grant Proposal)	2009 - Present
Vascular Medicine (Reviewer, Journal Article)	2009 - Present
Integrative Cancer Therapies (Reviewer, Journal Article)	2009 - Present
Free Radical Biology and Medicine (Reviewer, Journal Article)	2009 - Present
Cardiovascular Res (Reviewer, Journal Article)	2009 - Present
BMC Genomics (Reviewer, Journal Article)	2009 - Present
Am J Physiol-Endocrinology and Metabolism (Reviewer, Journal Article)	2009 - Present
Am Appl Physiol (Reviewer, Journal Article)	2009 - Present
Am J Physiol-Regulatory, Integrative and Comparative Physiology (Reviewer, Journal Article)	2009 - Present
International Journal of Physiology, Pathophysiology and Pharmacology (Editorial Review Board Member)	06/2008 - Present
Institute of Translational Health Sciences (ITHS) Pilot Grant Review (Reviewer, Grant Proposal)	2008 - 12/2009
J Mol Cell Cardiol (Reviewer, Journal Article)	2008 - Present
Life Sciences (Reviewer, Journal Article)	2008 - Present
Letters in Drug Design & Discovery (Reviewer, Journal Article)	2008 - Present
Informatica (Reviewer, Journal Article)	2008 - Present
Canadian J Physiol and Pharmacol (Reviewer, Journal Article)	2008 - Present
Acta Pharmacologica Sinica (Reviewer, Jorunal Article)	2008 - Present
The Open Diabtes Journal (Editorial Review Board Member)	06/2007 - Present
Clinical Experimental Pharmacology and Physiology (Reviewer, Journal Article)	2007 - Present
American Heart Association (AHA) (Reviewer, Grant Proposal)	2006 - 12/2009
The Donaghue Foundation of Connecticut (Reviewer, Grant Proposal)	2004 - 06/2007

Teaching Experience

Medicine, Lecture, Lecturer	Spring 2018 - 2018
Medicine, Lab, Preceptor	Summer 2018 - 2018
Medicine, Lecture, Lecturer	Spring 2018 - 2018
PHYSIO 715, Medicine, Course, Facilitator, Advanced Endocrinology	Fall 2018
Medicine, Lab, Preceptor	Annual 2017 - 2018
Medicine, Lecture, Lecturer	Spring 2017 - 2017
Medicine, Lab, Preceptor	Summer 2017 - 2017
Medicine, Lecture, Lecturer	Spring 2016 - 2016
Medicine, Lecture, Lecturer	Spring 2016 - 2016
Medicine, Lecture, Lecturer	Spring 2016 - 2016
Medicine, Lecture, Lecturer	Spring 2016 - 2016
Medicine, Lab, Preceptor	Summer 2016 - 2016
Graduate, Lab, Preceptor	Summer 2016 - 2016

Directed Student Learning

Research Advisor, Cardiovascular Response to Thermoregulatory Challenges Advised: Michael Adenawoola	2024 - Present
Research Advisor, Energy Metabolism in Myocardial Infarction Advised: Nadiyeh Rouhi	2024 - Present
Supervised Research, Lab Rotation Advised: Tawhida Islam	2023 - 2023
Supervised Research, Lab Rotation Advised: Michael Adenawoola	2023 - 2023
Supervised Research, Lab Rotation Advised: Lucy Tylor	2023 - 2023
Research Advisor, Obesity Cardiomyopathy Advised: Adewale James	2022 - 2023
Research Advisor, Activated Protein C and Epilepsy Advised: Linda Zoungrana	2021 - 2023
Supervised Research, Research Project: Activated protein C for Myocardial Infraction Treatment Advised: Mary Sampson	2018 - 2018
Research Advisor, Research Project: Age-related Impaired Stress Signaling Pathways Advised: Andrew Walker	2018 - 2018
Supervised Research, Advised: Osvaldo Gonzalez	2018 - 2018
Supervised Research, Advised: Kyle Moore	2018 - 2018
Supervised Research, Advised: Michael Deseke	2018 - 2018
Supervised Research, Advised: Michael Deseke	2017 - 2017
Supervised Research, Advised: Kyle Moore	2017 - 2017
Supervised Research, Advised: Rivera Gonzalez	2017 - 2017
Research Advisor, The Cardioprotective Effects of Humanin Advised: Thomas Rousselle	2017 - 2018
Supervised Research, Research Project: AMPK Signaling in the Aged Heart Advised: Chelsea Luckett	2017 - 2017
Supervised Research, The Structure-activity Relationship of Ginsenosides on Hypoxia-reoxygenation Induced Apoptosis of Cardiomyocytes Advised: Ruiqi Feng	2017 - 2017
Supervised Research, Characterize the antiinflammtion activities of natural products from herb medicine Advised: Ruiqi Feng	2016 - 2017
Supervised Research, Advised: Tyler Lomax	2016 - 2016
Supervised Research, Advised: Laura Coats	2016 - 2016
Research Advisor, Metformin Modulates Contractile Functions of Isolated Cardiomyocytes Advised: Amit Bajaj	2016 - 2016
Research Advisor, Characterize the antiinflammation activities of natural products from herb medicine Advised: Ruiqi Feng	2016 - 2016
Supervised Research, The Cardioprotective Effect of Aspirin Advised: Shaoxin Lu	2016 - 2016
Supervised Research, The Principle of Immunoblotting Advised: Chelsea Luckett	2016 - 2016
Supervised Research, Advised: Kai Wang	2015 - 2016
Research Advisor, Advised: Xingchi Chen	2015 - 2016
Research Advisor, Metformin and AMPK Activation Advised: George Techiryan	2014 - 2015
Dissertation Committee Member, Effects of flow on reactive oxygen species production in brain versus aortic endothelial cells Advised: Bethany Pond	2014 - 2015
Dissertation Committee Member, Effects of glucose and flow on reactive oxygen species in brain artery endothelial cells Advised: Stephen Mele	2014 - 2015
Research Advisor, Sestrin2 and AMPK Signaling Pathways Advised: Emmanuel Yawson	2014 - 2015
Research Advisor, Xanthohumol, a nature prenylated chalconoid, selectively inhibits the proliferation of neurotumor Advised: Xingchi Chen	2013 - 2015
Research Advisor, Limiting ischemic injury by pharmacologically administering antithrombin or modulating the glucocorticoid receptor activity Advised: Yina Ma	2013 - 2015
Research Advisor, AMPK modulates contractile function of cardiomyocytes Advised: Si Chen	2012 - 2014
Dissertation Defense Committee Member, The Cardioprotective Effects of iPS Stem Cells Advised: Michalis Mastri	2012 - 2012
Research Advisor, Cellular Effects of Weitaichun, a natural compound, in human prostate cancer Advised: Jee Park	2011 - 2013
Doctoral Advisory Committee Member, The Redox Regulation in the Aneurysm Advised: Nicholas Lian	2011 - 2013
Dissertation Committee Member, The Inflammation Response in the Endothelial Cells during Hyopoxia and Reoxygenation Advised: Liwei Wang	2010 - 2012
Research Advisor, Cellular effects of small molecule AMPK activator in prostate cancer Advised: Daniel Plumeri	2010 - 2012
Research Advisor, Potential role of the GLUT4 tether TUG in AMPK-mediated glucose uptake Advised: Mark Bryniarski	2010 - 2012
Research Advisor, Activated protein C modulates cardiac metabolism and augments autophagy in the ischemic heart Advised: Costa Robert	2010 - 2012
Dissertation Committee Member, The Pharmacological Mechanism of Melatonin on Behavior Advised: Ekue Ahamah-Blassi	2010 - 2010
Dissertation Defense Committee Member, The Cardioprotective Mechanisms of Novel Nitric Oxide Donors Advised: Max Mandelbaum	2010 - 2010
Dissertation Defense Committee Member, Intramuscular vascular endothelial growth factor therapy for heart failure: Roles of host derived factors and mobilization of bone marrow progenitor cells Advised: David Zisa	2010 - 2010
Research Advisor, Regulatory mechanisms of AMP-activated protein kinase in limiting myocardial infarction Advised: Alexander Morrison-Nozik	2009 - 2013
Research Advisor, Prostate-specific antitumor effects of natural compounds: isoliquitigenin and alternol Advised: Eddie Yeung	2009 - 2011
Doctoral Advisory Committee Member, Activity-dependent plasticity of neocortical inhibitory networks Advised: Yuanyuan Jiao	2009 - 2011
Doctoral Advisory Committee Member, Fetal pancreatic beta cell proliferation and insulin secretion in an ovine maternal obesity model Advised: Liren Zhang	2008 - 2009
Doctoral Advisory Committee Member, Study of placentomal angiogenesis during overnourished obese sheep pregnancy and the impact on fetal growth Advised: Yan Ma	2008 - 2010
Dissertation Committee Member, The Role of AMPK SIgnaling Pathway in Skeletal Muscle Development Advised: Xun Yan	2008 - 2009
Research Advisor, Pharmacological activation of SIRT1 protects against cardiac ischemic injury in the senescent heart Advised: Chao Tong	2008 - 2012
Doctoral Advisory Committee Member, Effects of maternal obesity on the skeletal muscle development in the offsprings and what the role of AMPK is Advised: Junfeng Tong	2007 - 2009
Doctoral Advisory Committee Member, AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction Advised: Subati Tuerdi	2007 - 2009
Research Advisor, Limiting cardiac ischemic injury by pharmacologically augmenting the AMPK signaling pathway Advised: Jingying Wang	2007 - 2011

Fellows supervised

Medical Student Research Program, Research Advisor, 1 fellows supervised, Medical Student	05/2024 - Present
R01HL158515, Post-Doc Advisor, 1 fellows supervised, Postdoc Fellow	01/2022 - Present
Medical Student Research Program, Research Advisor, 1 fellows supervised, Medical Student	01/2021 - 05/2023
Visiting Fellow, Research Advisor, 1 fellows supervised, Visiting Scholar	12/2018 - 12/2019
Visiting Fellow, Research Advisor, 1 fellows supervised	08/2018 - 06/2019
NIH 1R01GM124108, Post-Doc Advisor, 1 fellows supervised	08/2018 - 06/2022
Visiting Fellow, Research Advisor, 1 fellows supervised	01/2018 - 06/2019
Visiting Fellow, Research Advisor, 1 fellows supervised	07/2017 - 06/2020
Visiting Fellow, Research Advisor, 1 fellows supervised	06/2017 - 05/2018
NIH 1R01AG049835, Post-Doc Advisor, 1 fellows supervised	05/2017 - 06/2019
Visiting Fellow, Research Advisor, 1 fellows supervised	02/2017 - 08/2017
Visiting Fellow, Research Advisor, 1 fellows supervised	12/2016 - 11/2017
Visiting Fellow, Research Advisor, 1 fellows supervised	09/2016 - 08/2017
Visiting Fellow, Research Advisor, 1 fellows supervised	07/2016 - 06/2017
Visiting Fellow, Research Advisor, 1 fellows supervised	07/2016 - 06/2017
Visiting Scholar, Research Advisor, 1 fellows supervised	11/2015 - 10/2016
NIH R21AG044820, Research Advisor, 1 fellows supervised	11/2014 - 09/2017
NIH R21AG044820, Research Advisor, 1 fellows supervised	11/2014 - 08/2017
ADA 1-14-BS-131, Research Advisor, 1 fellows supervised	03/2014 - 03/2016
SUNY Buffalo-Capital Medical University Excahnge Program, Research Advisor, 1 fellows supervised	10/2013 - 09/2014
Visiting Scholar, Research Advisor, 1 fellows supervised	09/2012 - 08/2013
Visiting Scholar, Research Advisor, 1 fellows supervised	07/2012 - 09/2012
Visiting Scholar, Research Advisor, 1 fellows supervised	12/2011 - 11/2012
Visitng Scholar, Research Advisor, 1 fellows supervised	11/2011 - 10/2012
Visiting Scholar, Research Advisor, 1 fellows supervised	03/2010 - 02/2011
Visiting Scholar, Research Advisor, 1 fellows supervised	12/2009 - 11/2010
Visiting Fellow, Research Advisor, 1 fellows supervised	10/2008 - 09/2009
Visiting Scholar, Research Advisor, 1 fellows supervised	09/2007 - 08/2008

Residency Training

SUNY Buffalo Resident Research Training, Training Faculty	2012 - 06/2015
SUNY Buffalo Resident Reserach Training, Research Advisor	2011 - 07/2012

Extramural, The Regulation of Immunometabolism by Activated Protein C, NIH/NIGMS	07/2024 - Present
Extramural, Metformin Therapy for Ischemic Insult and Reperfusion Injury in Aging, NIH/NIA	09/2023 - 08/2025
Extramural, A Stress Inducible Protein Sestrin2 in Heart Failure, VA Merit Award	04/2022 - 03/2026
Extramural, Metformin Therapy for Ischemic Insult and Reperfusion Injury in Aging, NIH/NIA	09/2021 - 08/2023
Extramural, MIF and Cardiovascular Inflammation, NIH/NHBLI	07/2021 - 06/2025
Extramural, Activated Protein C and Cardiac Inflammatory Response, NIH/NIGMS	04/2018 - 03/2022
Extramural, A Novel Mechanism of Stromal Cell-derived Factor-1 Protection Against Diabetic Cardiomyopathy, NIH/NHBLI	05/2017 - 03/2022
Extramural, Glucose transport in the ischemic heart, American Diabetes Association (ADA)	01/2017 - 12/2019
Extramural, AMPK-SIRT1 Signaling in the Adaptive Metabolic Response, NIH/NIA	04/2015 - 03/2020
Extramural, Protease Activated Receptor-1 Signaling by Coagulation Proteases, NIH/NHLBI	12/2014 - 11/2015
Extramural, Role of Sestrin2 in Prevention of Age-related Cardiomyopathy, NIH/NIA	06/2014 - 05/2017
Extramural, Mitochondrial mechanism and novel therapeutic targets in atrial fibrillation, NIH/NHBLI	04/2014 - 03/2018
Extramural, Stress Signaling in the Aged Heart, American Heart Association (AHA)	01/2014 - 12/2015
Extramural, Sestrin2 Modulates Glucose Transport in the Ischemic Heart, American Diabetes Association	01/2014 - 12/2016
Extramural, Developmental programming of cardiovascular disease risk by maternal phytosterol consumption, NIH/NIDDK	09/2013 - 08/2018
Extramural, Sestrin2: A Novel Signaling Component in the Senescent Heart, NIH/NIA	04/2013 - 03/2015
Extramural, Serpin Regulation of Coagulation Proteases, NIH/NHBLI	07/2012 - 06/2014
Extramural, Optimizing Cardiac Function in Aging via a Novel Signaling Pathway, American Heart Association (AHA)	07/2012 - 06/2015
Extramural, Aging-associated Cardiovascular Disease and Diabetes, American Diabetes Association (ADA)	01/2012 - 12/2012
Extramural, Aging associated Alterations in Ischemic Glucose Transport by the MIF-AMPK Pathway, American Diabetes Association (ADA)	01/2011 - 12/2013
Extramural, Activated Protein C Ameliorates Cardiac Injury during Ischemia/Reperfusion, American Heart Association (AHA)	07/2010 - 06/2012
Extramural, Zannoni Summer Undergraduate Research Fellowship (SURF), American Society for Pharmacology and Experimental Therapeutics (ASPET)	07/2010 - 06/2012
Extramural, Protease Activated Receptor-1 Signaling by Coagulation Proteases, NIH/NHBLI	04/2010 - 03/2014
Extramural, Wyoming IdeA Networks of Biomedical Research Excellence, Aging-associated Alterations in Signaling, National Center for Research Resources (NCRR)	05/2009 - 07/2014
Intramural, Glucose Transporters Regulated by AMP-activated Protein Kinase, University of Wyoming College of Health Sciences	05/2009 - 06/2009
Intramural, Ph.D. Candidacy (Jingying Wang) stipend support, University of Wyoming Graduate School	01/2009 - 12/2011
Extramural, Macrophage Migration Inhibitory Factor in the Heart, National Center for Research Resources (NCRR)	07/2008 - 06/2009
Extramural, Alterations in AMP-activated Protein Kinase Signaling with Aging, American Federation for Aging Research (AFAR)	07/2008 - 09/2010
Intramural, Aging-associated Alterations in Cardiac MIF-AMPK Signaling during Ischemia, NIH	06/2008 - 05/2009
Extramural, Regulation of Stress Signaling in the Senescent Heart, NIH/NIA	04/2008 - 03/2010
Extramural, Aging-associated Alterations in Heart Stress Signaling during Ischemia/Reperfusion, American Heart Association (AHA)	01/2008 - 06/2012
Intramural, Equipment Support, University of Wyoming Northern Rockies Regional INBRE, 5P20RR016474-07	11/2007 - 01/2010
Extramural, Regulation of Glucose Transport in the Ischemic Heart, NIH/NHBLI	04/2005 - 03/2009
Intramural, Mouse Hepatocyte Model to Investigate Stress Response Mechanisms in Aging, NIDDK, The Liver Center Pilot Grant, Yale University	09/2002 - 08/2003
Extramural, Regulation of Glucose Transport in the Ischemic Heart, NIH/NHBLI	09/2000 - 07/2005

Ji Li, PhD

Biography

Education

Current Positions

Academic Appointments or Other Previous Appointments

Sponsored Program Funding

Publications

Journal Article

Review Article

Abstracts

Book Chapter

Clinical Trial

Editorial