Sumana Ghosh
Instructor
Department:
SOM-Otolaryngology - Head and Neck Surgery
Email:
sghosh@umc.edu
Work Phone:
(601) 984-5162
Education
| Southern Illinois University School of Medicine, Springfield, IL, US., PhD, Pharmacology and Neuroscience | 2017 |
| University of Leicester, Leicester, United Kingdom., MS, Cancer Cell and Molecular Biology | 2011 |
| Bangalore University, Bangalore, India., MS, Biochemistry | 2009 |
| Bangalore University, Bangalore, India., BS, Biotechnology, Biochemistry and Genetics | 2007 |
Sponsored Program Funding
Publications
Research News | |
| Keeping the neurons alive in the deaf ears”- | |
Bioarchive article | |
| Ghosh S, Wineski R, Pittman M, Lopez I, Ishiyama A, Thapa P, Walters BJ. Identification of putative GATA3 regulatory elements and comparison of GATA3 distribution in cochleae of mice, rats, macaques, and human | 2022 |
Journal Article | |
| McGovern MM, Ghosh S, Dupuis C, Walters BJ, Groves AK. Reprogramming with Atoh1, Gfi1, and Pou4f3 promotes hair cell regeneration in the adult organ of Corti PNAS Nexus. 2024 Oct 4;3(10):pgae445 | 2024 |
| Ghosh S, Lewis M, Walters BJ. Comparisons of ethylenediaminetetraacetic acid and rapid decalcifier solution for studying human temporal bones by immunofluorescence. Laryngoscope Investig Otolaryngol. 2020 Aug 26;5(5):919-927 | 2020 |
| Bhatta P, Dhukwa A, Sheehan K, Al Ameri, Borse V, Ghosh S, Sheth S, Mamillapalli C, Rybak L, Ramkumar V, Mukherjea D. Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea Sci Rep. 2019 Mar 11;9(1):4131. | 2019 |
| Ghosh S, Sheth S, Sheehan K, Mukherjea D, Dhukhwa A, Borse V, Rybak LP, Ramkumar V. The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss. Front Cell Neurosci. 2018 Aug 21;12:271. | 2018 |
| Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity Cell Death Dis. 2017 Jul 13;8(7):e2921. | 2017 |
| Kaur T, Borse V, Sheth S, Sheehan K, Ghosh S, Tupal S, Jajoo S, Mukherjea D, Rybak LP, Ramkumar V. Adenosine A1 Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea Journal of Neuroscience 6 April 2016, 36 (14) 3962-3977. | 2016 |
| Stansak K, Baum L, Ghosh S, Thapa P, Vanga V, Walters BJ. A Novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting. Front Cell Dev Biol. 2024 May 17; 12:1394031. | |
Review Article | |
| Ghosh S, Stansak K and Walters BJ. Cannabinoid Signaling in Auditory Function and Development Front. Mol. Neurosci. 14:678510. | 2021 |
| Mukherjea D, Ghosh S, Bhatta P, Sheth S, Tupal S, Borse V, Brozoski T, Sheehan KE, Rybak LP, Ramkumar V. Early investigational drugs for hearing loss Expert Opin Investig Drugs.2015 Feb;24(2):201-17. | 2015 |
Book Chapter | |
| Ramkumar V, Borse V, Ghosh S, Kaur T, Sheehan K, Sheth S., Dukhwa A, Tupal S, Mukherjea D., Rybak L. Role of Adenosine Receptors in Auditory Functions. Adenosine Receptors- Pharmacology, Functions and Therapeutic Aspects, Nova Science Publishers, 2015. | 2015 |
| Ghosh S, Casey G, Stansak K, Thapa P, and Walters BJ. “An Efficient Method to Detect Messenger RNA (mRNA) in the Inner Ear by RNAscope In-Situ Hybridization”. Neuromethods, Vol 176. Humana, New York, NY, 2022. | |
Presentations
| Platform Presentations, Role of Transcription Factor Six2 in the Development of Vestibular Epithelia, 48th Annual Mid Winter Meeting | 02/2025 |
| Poster Presentation, Pcp Auto Count: An Imagej Plug-In Developed Using Ai (Actual Intelligence) for Automated Cell Counting and Measurement of Planar Cell Polarity, 48th Annual Mid Winter Meeting ARO | 02/2025 |
| Poster Presentation, Differential Effects of Tmie Deletion on Canal and Otolith Function in Mice, Association for Research in Otolaryngology, Orlando, FL | 02/2025 |
| Platform Presentations, The Essential Role of Cannabinoid Receptor (CB2) in the Cochlea in Otoprotection., Association for Research in Otolaryngology, San Diego, CA | 02/2025 |
| Poster Presentation, Proper Dosage of the Transcription Factor Six2 is Needed for Vestibular Organ Development. | 01/2025 |
| Platform Presentations, The Transcription Factor Six2 Regulates Morphogenesis of Vestibular Epithelia and Maturation of Vestibular Hair Cells., Anaheim, CA | 02/2024 |
| Poster Presentation, Testing ZBTB6 Binding Affinity To Human-Specific GATA3 Regulatory Elements by Electrophoretic Mobility Shift Assay (EMSA)., UMMC | 07/2023 |
| Platform Presentations, Six2 Regulates Morphogenesis and Planar Cell Polarity (PCP) of Vestibular Epithelia, Association for Research in Otolaryngology | 02/2023 |
| Platform Presentations, The Novel Role of Transcription Factor Six2 in Vestibular Planar Cell Polarity, Association for Research in Otolaryngology | 02/2022 |
| Poster Presentation, Identification of Putative GATA3 Regulatory Elements and Comparison of GATA3 Immunostaining Across Rodent, Monkey, and Human Cochleae, Association for Research in Otolaryngology, San Jose, CA | 02/2021 |
| Poster Presentation, GATA3 Expression in Cochlear Tissues is Conserved across Mice, Rats, Macaques, and Humans., Association for Research in Otolaryngology, San Jose, CA | 01/2020 |
| Poster Presentation, AP-001/NPD1 Prevents Cisplatin-induced Hearing Loss in the Rat and Confers Protection Through Unique Pleiotropic Actions on Multiple Target, Assciation for Research in Otolaryngology, San Diego, CA | 02/2018 |
| Poster Presentation, Regulator of G-protein Signaling 17 (RGS17), a Novel Mediator of Cisplatin-induced ototoxicity., Association for Research in Otolaryngology, San Diego, CA | 02/2018 |
| Poster Presentation, Transplatin: An effective treatment for noise induced hearing loss. Abstract#578. Association for Research in Otolaryngology, Association for Research in Otolaryngology, San Diego, CA | 02/2014 |
| Poster Presentation, Epigallocatechin Gallate (EGCG) Protects Against Cisplatin-Induced Hearing Loss by Altering the Balance Between STAT1 and STAT3 Proteins, Association for Research in Otolaryngology | 02/2014 |
| Invited Talk, A Journey to understand hearing and balance: Stories of Two Transcription Factors in Development and Regeneration of Mammalian Inner Ear.”, anderbilt University Medical Center. Department of Hearing and Speech Science | |
| Platform Presentations, The Transcription Factor Six2 Regulates Morphogenesis of Vestibular Epithelia and Maturation of Vestibular Hair Cells, Association for Research in Otolaryngology, Anaheim, CA | |
| Poster Presentation, PCP-Autocount: A Novel ImageJ Plug-In for Automated Quantification of Planar Cell Polarity, Association for Research in Otolaryngology, Anaheim, CA | |
| Poster Presentation, A Novel Approach for the Automation of Spiral Ganglion Neuron Quantification Using an ADARB1 Antibody, Association for Research in Otolaryngology, Anaheim, CA | |
| Poster Presentation, Comparisons of Various Pretreatments to Improve Immunofluorescence Staining of Human Temporal bone, Association for Research in Otolaryngology, Baltimore, MD | |
| Poster Presentation, Caffeine Consumption Exacerbates Cisplatin-Induced Hearing Loss in the Rat., Association for Research in Otolaryngology, San Diego, CA | |
| Poster Presentation, Expression, Regulation and Function of Cannabinoid Receptor 2 in the cochlea., Association for Research in Otolaryngology, San Diego, CA | |
| Poster Presentation, Dysregulation of TRPV1 Channel Activity by TNF-α and H2O2 in Noise Induced Hearing Loss., Association for Research in Otolaryngology, San Diego, CA | |
| Poster Presentation, Modulation of the STAT1/STAT3 Signaling Pathway by Epigallocatechin 3-Gallate (EGCG) Protects Against Cisplatin Ototoxicity, Association for Research in Otolaryngology |
Honors, Awards, and Recognition
| Travel Award, Association for Research in Otolaryngology | 2021 |
| Travel Award, Association for Research in Otolaryngology | 2019 |
Professional Membership and Service
| Association for Research in Otolaryngology, Member | 2013 - Present |
Committee Service
| Postdoc Advisory Committee, Member | |
| Student postdoc ARO (spARO), Steering Committee Member | |
| ARO Education Committee, Steering Committee Member |
Other Service
| Ear, Nose &Throat Journal | |
| Served as Ad-hoc reviewer for the following 1.Frontiers in Cellular Neuroscience 2.Scientific Reports 3.Ear, Nose & Throat Journal 4.Biomed Research International 5.Cellular and Molecular biology 6.Neuroscience Letters 7.Otology and Neurotology 8. JARO |
Teaching Experience
| Graduate, Course, Lecturer | Spring 2026 |
| Graduate, Course, Lecturer, Biochemistry for Neuroscientists | Spring 2026 |
| Graduate, Lecture, Lecturer, AUD 704 1 A&P of Hearing & Balance Mechanisms | Fall 2025 |
Directed Student Learning
| Supervised Research, Advised: Beth Baker | |
| Supervised Research, Advised: Vineel Vanga | |
| Supervised Research, Advised: Katie Churilla | |
| Supervised Research, Advised: Michael Pittman | |
| Supervised Research, Advised: Kaylee Zettler |