Letter |
George EM, Granger JP, Response to: Using Carbon Monoxide Releasing Molecules in Models of Pre-Eclampsia: When Should We Be Monitoring Vascular Effects? American journal of hypertension, 2017 Oct 1;30(10):e11 | 2017 |
News |
George EM, Granger JP, Hypertension: A new genetic clue to unravel the origins of pre-eclampsia. Nature reviews. Nephrology, 2017 Oct;13(10):599-600 | 2017 |
Journal Article |
George EM The disease of theories: unravelling the mechanisms of preeclampsia The Biochemist. 39:1: 22-25. | 2017 |
Eddy AC, Chapman H, George EM, Acute Hypoxia and Chronic Ischemia Induce Differential Total Changes in Placental Epigenetic Modifications. Reproductive sciences (Thousand Oaks, Calif.), 2019 Jun;26(6):766-773 | 2019 |
Eddy AC, Bidwell GL 3rd, George EM, Pro-angiogenic therapeutics for preeclampsia. Biology of sex differences, 2018 Aug 25;9(1):36 | 2018 |
George EM, Cockrell K, Arany M, Stec DE, Rimoldi JM, Gadepalli RSV, Granger JP, Carbon Monoxide Releasing Molecules Blunt Placental Ischemia-Induced Hypertension. American journal of hypertension, 2017 Sep 1;30(9):931-937 | 2017 |
Logue OC, Mahdi F, Chapman H, George EM, Bidwell GL 3rd, A Maternally Sequestered, Biopolymer-Stabilized Vascular Endothelial Growth Factor (VEGF) Chimera for Treatment of Preeclampsia. Journal of the American Heart Association, 2017 Dec 8;6(12) | 2017 |
Logue OC, George EM, Bidwell GL 3rd, Preeclampsia and the brain: neural control of cardiovascular changes during pregnancy and neurological outcomes of preeclampsia. Clinical science (London, England : 1979), 2016 Aug 1;130(16):1417-34 | 2016 |
Logue OC, McGowan JW, George EM, Bidwell GL 3rd, Therapeutic angiogenesis by vascular endothelial growth factor supplementation for treatment of renal disease. Current opinion in nephrology and hypertension, 2016 Sep;25(5):404-9 | 2016 |
Flanagan TW, Files JK, Casano KR, George EM, Brown DT, Photobleaching studies reveal that a single amino acid polymorphism is responsible for the differential binding affinities of linker histone subtypes H1.1 and H1.5. Biology open, 2016 Feb 24;5(3):372-80 | 2016 |
George EM, Mahdi F, Logue OC, Robinson GG, Bidwell GL 3rd, Corneal Penetrating Elastin-Like Polypeptide Carriers. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2016 Apr;32(3):163-71 | 2016 |
Warrington JP, Coleman K, Skaggs C, Hosick PA, George EM, Stec DE, Ryan MJ, Granger JP, Drummond HA, Heme oxygenase-1 promotes migration and β-epithelial Na+ channel expression in cytotrophoblasts and ischemic placentas. American journal of physiology. Regulatory, integrative and comparative physiology, 2014 May;306(9):R641-6 | 2014 |
George EM, Garrett MR, Granger JP, Placental ischemia induces changes in gene expression in chorionic tissue. Mammalian genome : official journal of the International Mammalian Genome Society, 2014 Jun;25(5-6):253-61 | 2014 |
George EM, Warrington JP, Spradley FT, Palei AC, Granger JP, The heme oxygenases: important regulators of pregnancy and preeclampsia. American journal of physiology. Regulatory, integrative and comparative physiology, 2014 Oct 1;307(7):R769-77 | 2014 |
Chinthalapudi K, Rangarajan ES, Patil DN, George EM, Brown DT, Izard T, Lipid binding promotes oligomerization and focal adhesion activity of vinculin. The Journal of cell biology, 2014 Dec 8;207(5):643-56 | 2014 |
George EM, New approaches for managing preeclampsia: clues from clinical and basic research. Clinical therapeutics, 2014 Dec 1;36(12):1873-1881 | 2014 |
Hammond BR, Johnson BA, George ER, Oxidative photodegradation of ocular tissues: beneficial effects of filtering and exogenous antioxidants. Experimental eye research, 2014 Dec;129:135-50 | 2014 |
George EM, Liu H, Robinson GG, Bidwell GL, A polypeptide drug carrier for maternal delivery and prevention of fetal exposure. Journal of drug targeting, 2014 Dec;22(10):935-47 | 2014 |
Rana S, Rajakumar A, Geahchan C, Salahuddin S, Cerdeira AS, Burke SD, George EM, Granger JP, Karumanchi SA, Ouabain inhibits placental sFlt1 production by repressing HSP27-dependent HIF-1α pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014 Oct;28(10):4324-34 | 2014 |
George EM, Granger JP, Heme oxygenase in pregnancy and preeclampsia. Current opinion in nephrology and hypertension, 2013 Mar;22(2):156-62 | 2013 |
George EM, Hosick PA, Stec DE, Granger JP, Heme oxygenase inhibition increases blood pressure in pregnant rats. American journal of hypertension, 2013 Jul;26(7):924-30 | 2013 |
George EM, Palei AC, Dent EA, Granger JP, Sildenafil attenuates placental ischemia-induced hypertension. American journal of physiology. Regulatory, integrative and comparative physiology, 2013 Aug 15;305(4):R397-403 | 2013 |
Warrington JP, George EM, Palei AC, Spradley FT, Granger JP, Recent advances in the understanding of the pathophysiology of preeclampsia. Hypertension (Dallas, Tex. : 1979), 2013 Oct;62(4):666-73 | 2013 |
George EM, Arany I, Induction of heme oxygenase-1 shifts the balance from proinjury to prosurvival in the placentas of pregnant rats with reduced uterine perfusion pressure. American journal of physiology. Regulatory, integrative and comparative physiology, 2012 Mar 1;302(5):R620-6 | 2012 |
George EM, Palei AC, Granger JP, Endothelin as a final common pathway in the pathophysiology of preeclampsia: therapeutic implications. Current opinion in nephrology and hypertension, 2012 Mar;21(2):157-62 | 2012 |
George EM, Granger JP, Linking placental ischemia and hypertension in preeclampsia: role of endothelin 1. Hypertension (Dallas, Tex. : 1979), 2012 Aug;60(2):507-11 | 2012 |
Hall JE, Granger JP, do Carmo JM, da Silva AA, Dubinion J, George E, Hamza S, Speed J, Hall ME, Hypertension: physiology and pathophysiology. Comprehensive Physiology, 2012 Oct;2(4):2393-442 | 2012 |
George EM, Cockrell K, Aranay M, Csongradi E, Stec DE, Granger JP, Induction of heme oxygenase 1 attenuates placental ischemia-induced hypertension. Hypertension (Dallas, Tex. : 1979), 2011 May;57(5):941-8 | 2011 |
Tam Tam KB, George E, Cockrell K, Arany M, Speed J, Martin JN Jr, Lamarca B, Granger JP, Endothelin type A receptor antagonist attenuates placental ischemia-induced hypertension and uterine vascular resistance. American journal of obstetrics and gynecology, 2011 Apr;204(4):330.e1-4 | 2011 |
George EM, Granger JP, Mechanisms and potential therapies for preeclampsia. Current hypertension reports, 2011 Aug;13(4):269-75 | 2011 |
Speed JS, LaMarca B, Berry H, Cockrell K, George EM, Granger JP, Renal medullary endothelin-1 is decreased in Dahl salt-sensitive rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2011 Aug;301(2):R519-23 | 2011 |
George EM, Granger JP, Endothelin: key mediator of hypertension in preeclampsia. American journal of hypertension, 2011 Sep;24(9):964-9 | 2011 |
George EM, Arany M, Cockrell K, Storm MV, Stec DE, Granger JP, Induction of heme oxygenase-1 attenuates sFlt-1-induced hypertension in pregnant rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2011 Nov;301(5):R1495-500 | 2011 |
Ryan MJ, Gilbert EL, Glover PH, George EM, Masterson CW, McLemore GR Jr, LaMarca B, Granger JP, Drummond HA, Placental ischemia impairs middle cerebral artery myogenic responses in the pregnant rat. Hypertension (Dallas, Tex. : 1979), 2011 Dec;58(6):1126-31 | 2011 |
Hall ME, George EM, Granger JP, [The heart during pregnancy]. Revista espanola de cardiologia, 2011 Nov;64(11):1045-50 | 2011 |
George EM, Brown DT, Prothymosin alpha is a component of a linker histone chaperone. FEBS letters, 2010 Jul 2;584(13):2833-6 | 2010 |
George EM, Izard T, Anderson SD, Brown DT, Nucleosome interaction surface of linker histone H1c is distinct from that of H1(0). The Journal of biological chemistry, 2010 Jul 2;285(27):20891-6 | 2010 |
George EM, Cockrell K, Adair TH, Granger JP, Regulation of sFlt-1 and VEGF secretion by adenosine under hypoxic conditions in rat placental villous explants. American journal of physiology. Regulatory, integrative and comparative physiology, 2010 Dec;299(6):R1629-33 | 2010 |
George EM, Granger JP, Recent insights into the pathophysiology of preeclampsia. Expert review of obstetrics & gynecology, 2010 Sep 1;5(5):557-566 | 2010 |
Hearst SM, Gilder AS, Negi SS, Davis MD, George EM, Whittom AA, Toyota CG, Husedzinovic A, Gruss OJ, Hebert MD, Cajal-body formation correlates with differential coilin phosphorylation in primary and transformed cell lines. Journal of cell science, 2009 Jun 1;122(Pt 11):1872-81 | 2009 |
Meshorer E, Yellajoshula D, George E, Scambler PJ, Brown DT, Misteli T, Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Developmental cell, 2006 Jan;10(1):105-16 | 2006 |
Speed JS, George EM, Arany M, Cockrell K, Granger JP, Role of 20-hydroxyeicosatetraenoic acid in mediating hypertension in response to chronic renal medullary endothelin type B receptor blockade. PloS one, 2011;6(10):e26063 | |
George EM, Colson D, Dixon J, Palei AC, Granger JP, Heme Oxygenase-1 Attenuates Hypoxia-Induced sFlt-1 and Oxidative Stress in Placental Villi through Its Metabolic Products CO and Bilirubin. International journal of hypertension, 2012;2012:486053 | |
George EM, Stout JM, Stec DE, Granger JP, Heme oxygenase induction attenuates TNF-α-induced hypertension in pregnant rodents. Frontiers in pharmacology, 2015;6:165 | |
George EM, Liu H, Robinson GG, Mahdi F, Perkins E, Bidwell GL 3rd, Growth factor purification and delivery systems (PADS) for therapeutic angiogenesis. Vascular cell, 2015;7(1):1 | |
Bidwell GL 3rd, George EM, Maternally sequestered therapeutic polypeptides - a new approach for the management of preeclampsia. Frontiers in pharmacology, 2014;5:201 | |
Review Article |
Palei AC, Spradley FT, Warrington JP, George EM, and Granger JP Pathophysiology of Hypertension in Preeclampsia: A Lesson in Integrative Physiology Acta Physiol (Oxf). 2013 Apr 16. Epub ahead of print | 2013 |
Abstracts |
Colson AS, DixonJ, George EM, and Granger JP Heme oxygenase-1 attenuates hypoxia-induced superoxide production in placental villi FASEB J March 17, 2011 25:836.9 | 2011 |
George EM, Cockrell K, Arany M, Stec DE, and Granger JP Heme oxygenase-1 induction attenuates sFlt-1 induced hypertension in pregnant rats FASEB J March 17, 2011 25:836.7 | 2011 |
George EM, Adair TH, and Granger JP Regulation of sFlt-1 secretion by adenosine receptor signaling in rat placental villous explants FASEB J, Apr 2010: 24: 1041.11 | 2010 |
Book Chapter |
George EM and Granger JP Animal models for investigating pathophysiological mechanisms of preeclampsia In Lindheimer MD, Roberts JM, and Cunningham FG (Eds.), Chesley’s Hypertensive Disorders of Pregnancy, 4th Edition. Elsevier. | 2015 |
Granger JP and George EM Role of the Kidneys in Hypertension In Schrier RW, Coffman TM, Falk RJ, Molitoris BA, and Neilson EG. (Eds.), Schrier’s Diseases of the Kidney, 9th ed. Lippincott Williams & Wilkins. | 2012 |
George EM and Granger JP Vascular Mechanisms of Hypertension in the Pathophysiology of Preeclampsia In Hill, J.A., Griendling, K., and Olson, E.N. (Eds.), Muscle: Fundamental Biology and Mechanisms and Disease. Elsevier. | 2012 |
Editorial |
George EM, Bidwell GL, STOX1: a new player in preeclampsia? Hypertension (Dallas, Tex. : 1979), 2013 Mar;61(3):561-3 | 2013 |