Kevin B. Freeman
Professor
Department:
SOM-Psychiatry
Email:
kfreeman@umc.edu
Work Phone:
(601) 815-5622
Biography
Dr. Freeman is a behavioral pharmacologist specializing in the study of substance abuse. He completed a Ph.D. in Psychology (Behavioral Neuroscience Track) from American University in 2007 and completed a post-doctoral fellowship in Pharmacology at the University of Mississippi Medical Center (UMMC) in 2010. Dr. Freeman joined the faculty in the Department of Psychiatry and Human Behavior at UMMC in 2010 at the Instructor level and was promoted to Assistant and Associate Professor in 2012 and 2017, respectively. Dr. Freeman's NIH-funded research focuses on the development of novel abuse-deterrent formulations for prescription opioids. Dr. Freeman also studies the behavioral pharmacology of polydrug abuse (e.g., combinations of stimulants and opioids). In addition to conducting research, Dr. Freeman directs the Office of Medical Student and Resident Research for the Department of Psychiatry and Human Behavior. He teaches across all levels of the institution including graduates students, medical students, and residents. Lastly, Dr. Freeman speaks regularly at schools and other community meetings to raise awareness about the dangers of substance abuse, the related costs to society, and the ways in which these problems are being addressed by the research enterprise at UMMC.
Education
| University of Mississippi Medical Center; Dept. of Psychiatry & Human Behavior, Postdoc, Pharmacology | 2010 |
| American University (Washington, DC), PhD, Psychology/Behavioral Neuroscience | 2007 |
| University of Mississippi, BA, Psychology | 2001 |
| University of Mississippi, BA, Political Science/English | 1996 |
Current Positions
| Associate Professor, School of Medicine, Department of Psychiatry | 07/2017 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Academic Appointments or Other Previous Appointments
| Assistant Professor, University of Mississippi Medical Center, School of Medicine, Department of Psychiatry | 06/2012 - 06/2017 |
| Instructor, University of Mississippi Medical Center, School of Medicine, Department of Psychiatry | 04/2010 - 05/2012 |
Sponsored Program Funding
| Extramural, An opioid/cannabinoid analgesic that boosts pain relief and blocks opiate reward, National Institute on Drug Abuse (NIDA) | 07/2018 - 06/2020 |
| Extramural, Unpredictable access to cocaine as a determinant of drug choice, National Institute on Drug Abuse (NIDA) | 04/2018 - 03/2023 |
| Extramural, Tolerance and physical dependence after chronic benzodiazepine treatment, National Institute on Drug Abuse (NIDA) | 07/2017 - 06/2022 |
| Extramural, Deterrents for prescription opioid abuse, National Institute on Drug Abuse (NIDA) | 09/2015 - 05/2026 |
| Extramural, Anxiolytic and abuse-related effects of BZ Ligands, National Institute on Drug Abuse (NIDA) | 03/2015 - 12/2019 |
| Extramural, Delay discounting and the choices to take a drug, National Institute on Drug Abuse (NIDA) | 06/2013 - 06/2017 |
| Extramural, Fat, sweet taste, and cocaine reinforcement in obese and lean Zucker rats, National Institute on Drug Abuse (NIDA) | 06/2012 - 05/2015 |
| Intramural, Assessment of sucrose, saccharin, and corn oil reward in obese and lean rats, The University of Mississippi Medical Center (IRSP) | 05/2011 - 04/2012 |
Publications
Journal Article | |
| Zamarripa, C.A., Pareek, T., Schrock, H.M., Prisinzano, T.E., Blough, B.E., Sufka, K.J., Freeman, K.B. The kappa-opioid receptor agonist, triazole 1.1, reduces oxycodone self-administration and enhances oxycodone-induced thermal antinociception in male rats Psychopharmacology. 2021; epub ahead of print | 2021 |
| Zamarripa, C.A., Naylor, J.E., Huskinson, S.L., Townsend, E.A., Prisinzano, T.E., Freeman, K.B Kappa opioid agonists reduce oxycodone self-administration in male rhesus monkeys Psychopharmacology. 2020; 237:1471-1480 | 2020 |
| Zamarripa, C.A., Patel, T.R., Williams, B.C., Pareek, T., Schrock, H.M., Prisinzano, T.E., Freeman, K.B. The kappa-opioid receptor agonist, nalfurafine, blocks acquisition of oxycodone self-administration and oxycodone’s conditioned rewarding effects in male rats Behavioural Pharmacology. 2020; 31:792-797 | 2020 |
| Huskinson, S.L., Platt, D.M., Brasfield, M., Follett, M.E., Prisinzano, T.E., Blough, B.E., Freeman, K.B. Quantification of observable behaviors induced by kappa opioid agonists in male rhesus monkeys Psychopharmacology. 2020; 237:2075-2087 | 2020 |
| Gerb, S.A., Cook, J.E., Gochenauer A.E., Young, C.S., Fulton, L.K., Grady, A.W., Freeman, K.B. Ketamine tolerance in Sprague-Dawley rats following chronic ketamine, morphine, or cocaine administration Comparative Medicine. 2019;69:29-34 | 2019 |
| Huskinson, S.L, Freeman, K.B., Rowlett, J.K. Self-administration of benzodiazepine and cocaine combinations by male and female rhesus monkeys in a choice procedure: Role of 1 subunit-containing GABAA receptors Psychopharmacology. 2019; 236:3271-3279 | 2019 |
| Witkin, J.M., Cerne, R., Davis, P.G., Freeman, K.B., do Carmo, J.M., Rowlett, J.K., Methuki, K.R., Okun, A., Gleason, S.D., Li, X., Krambis, M.J., Poe, M., Li, G., Schkeryantz, J.M., Jahan, R., Yan, L., Guo, W., Golani, L.K., Anderson, W.H., Catlow, J.T., Jones, T.M., Porreca, F., Smith, J.L., Knopp, K.L., Cook, J.M. The 2,3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats Pharmacology, Biochemistry and Behavior. 2019; 180:22-31 | 2019 |
| Schmidt, M.F., Storrs, J.M., Freeman, K.B., Jack, C.R., Turner, S.T., Griswold, M.E., Mosley, T.H. A comparison of manual tracing and FreeSurfer for estimating hippocampal volume over the adult lifespan Human Brain Mapping. 2018, 39:2500-2513 | 2018 |
| Negus, S.S., Freeman, K.B. Abuse potential of biased mu opioid receptor agonists Trends in Pharmacological Sciences. 2018; 39:916-919 | 2018 |
| Zamarripa, C.A., Edwards, S.R., Qureshi, H.N., Yi, J.Y., Blough, B.E., Freeman, K.B. The G-protein biased mu-opioid agonist, TRV130, produces reinforcing and antinociceptive effects that are comparable to oxycodone in rats Drug and Alcohol Dependence. 2018:192:158-162 | 2018 |
| Townsend EA, Platt DM, Rowlett JK, Roma PB, Freeman KB Reinforcing effectiveness of midazolam, ethanol, and sucrose: Behavioral economic comparison of a mixture relative to its component solutions Behavioural Pharmacology. 2017; 28:386-393 | 2017 |
| Lazenka, M.L., Moerke, M.J., Townsend, E.A., Freeman, K.B., Carroll, F.I., Negus, S.S. Dissociable effects of the kappa opioid receptor agonist nalfurafine on pain/itch-stimulated and pain/itch-depressed behaviors in male rats Psychopharmacology. 2017; Epub ahead of print | 2017 |
| Huskinson SL, Freeman KB, Petry NM, Rowlett JK Choice between variable and fixed cocaine alternatives in male rhesus monkeys Psychopharmacology. 2017; 234:2653-2364 | 2017 |
| Townsend E A, Naylor JE, Negus SS, Edwards SR, Qureshi HN, McLendon HW, McCurdy CR, Kapanda CN, do Carmo JM, Fernanda SD, Hall JE, Sufka KJ, Freeman KB Effects of nalfurafine on oxycodone reinforcement, thermal antinociception, and respiration: Modeling an abuse-deterrent opioid analgesic in rats Psychopharmacology. 2017, In Press | 2017 |
| Townsend EA, Freeman KB Comparison of cocaine reinforcement in lean and obese Zucker rats: Relative potency and reinstatement of extinguished operant responding Physiology & Behavior. 2016; 170:88-92 | 2016 |
| Huskinson SL, Naylor JE, Townsend EA, Rowlett JK, Blough JE, Freeman KB Self-administration and behavioral economics of second-generation synthetic cathinones in male rats Psychopharmacology. 2016; Epub ahead of print | 2016 |
| Huskinson SL, Myerson J, Green L, Rowlett JK, Woolverton WL, Freeman KB Shallow discounting of delayed cocaine by male rhesus monkeys when immediate food is the choice alternative Experimental and Clinical Psychopharmacology, 2016, Epub ahead of print | 2016 |
| Scmidt MF, Freeman KB, Windham BG, Griswold ME, Kullo IJ, Turner ST, Mosley TH Associations between serum inflammatory markers and hippocampal volume in a community sample Journal of the American Geriatrics Society. 2016; Epub ahead of print | 2016 |
| Huskinson SL, Woolverton WL, Green L, Myerson J, Freeman KB. Delay discounting of food by rhesus monkeys: Cocaine and food choice in isomorphic and allomorphic situations. Experimental and Clinical Psychopharmacology. 2015; 23(3):184-93. | 2015 |
| Townsend EA, Beloate LN, Huskinson SL, Roma PG, Freeman KB. Corn oil, but not cocaine, is a more effective reinforcer in obese than in lean Zucker rats. Physiol Behav. 2015; 143:136-41. | 2015 |
| Naylor JE, Freeman KB, Blough BE, Woolverton WL, Huskinson SL. Discriminative-stimulus effects of second generation synthetic cathinones in methamphetamine-trained rats. Drug Alcohol Depend. 2015; 149:280-4. | 2015 |
| Huskinson SL, Freeman KB, Woolverton WL. Self-administration of cocaine and remifentanil by monkeys under concurrent-access conditions. Psychopharmacology. 2015; 232(2):321-30. | 2015 |
| Freeman KB, Naylor JE, Prisinzano TE, Woolverton WL. Assessment of the kappa opioid agonist, salvinorin A, as a punisher of drug self-administration in monkeys. Psychopharmacology (Berl). 2014; 231(14):2751-8. | 2014 |
| Freeman KB, McMaster BC, Roma PG, Woolverton WL. Assessment of the effects of contingent histamine injections on the reinforcing effectiveness of cocaine using behavioral economic and progressive-ratio designs. Psychopharmacology (Berl). 2014 Jun;231(12):2395-403. | 2014 |
| Freeman KB, Heal DJ, McCreary AC, Woolverton WL. Assessment of ropinirole as a reinforcer in rhesus monkeys. Drug Alcohol Depend. 2012 Sep 1;125(1-2):173-7. | 2012 |
| Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nature Genetics. 2012; 44:545-551. | 2012 |
| Woolverton WL, Freeman KB, Myerson J, Green L. Suppression of cocaine self-administration in monkeys: Effects of delayed punishment. Psychopharmacology. 2012; 220:509-517. | 2012 |
| Freeman KB, Nonnemacher JE, Green L, Myerson J, Woolverton WL. Delay discounting in rhesus monkeys: Equivalent discounting of more and less preferred sucrose concentrations. Learning & Behavior. 2012; 40(1):54-60. | 2012 |
| Freeman KB, Woolverton WL. Self-administration of cocaine and remifentanil by monkeys: choice between single drugs and mixtures. Psychopharmacology. 2011; 215(2):281-90. | 2011 |
| Freeman KB, Wang Z, Woolverton WL. Self-administration of (+)-methamphetamine and (+)-pseudoephedrine, alone and combined, by rhesus monkeys. Pharmacol Biochem Behav. 2010; 95(2):198-202. | 2010 |
| Freeman KB, Woolverton WL. Self-administration of cocaine and nicotine mixtures by rhesus monkeys. Psychopharmacology. 2009; 207(1):99-106. | 2009 |
| Freeman KB, Green L, Myerson J, Woolverton WL. Delay discounting of saccharin in rhesus monkeys. Behav Processes. 2009; 82(2):214-8. | 2009 |
| Freeman KB, Kearns DN, Kohut SJ, Riley AL. Strain differences in patterns of drug-intake during prolonged access to cocaine self-administration. Behavioral Neuroscience. 2009; 123(1):156-64. | 2009 |
| Freeman KB, Verendeev A, Riley AL. Noradrenergic antagonism enhances the conditioned aversive effects of cocaine. Pharmacology, Biochemistry and Behavior. 2008; 88(4):523-32. | 2008 |
| Lombas AS, Freeman KB, Roma PG, Riley AL. Intravenous cocaine priming reinstates cocaine in-duced conditioned place preference Psicologica. 2008; 28:55-62 | 2008 |
| Freeman KB, Rice KC, Riley AL. Assessment of monoamine transporter inhibition in the mediation of cocaine-induced conditioned taste aversion. Pharmacology, Biochemistry and Behavior. 2005; 82(3):583-9. | 2005 |
| Freeman KB, Riley AL Cocaine-induced conditioned taste avoidance over extended conditioned stimulus-unconditioned stimulus intervals. Behavioural Pharmacology. 2005; 16(7):591-5. | 2005 |
| Busse GD, Freeman KB, Riley AL. The interaction of sex and route of drug administration in cocaine-induced conditioned taste aversions. Pharmacology, Biochemistry and Behavior. 2005; 81(4):814-20. | 2005 |
| Freeman KB, Konalieva MJ, Riley AL. Assessment of the contributions of Na+ channel inhibition and general peripheral action in cocaine-induced conditioned taste aversion. Pharmacology, Biochemistry and Behavior. 2005; 80(2):281-8. | 2005 |
| Feltenstein MW, Ford NG, Freeman KB, Sufka KJ. Dissociation of stress behaviors in the chick social-separation-stress procedure. Physiology & Behavior. 2002; 75(5):675-9 | 2002 |
| Balster RL, Nader MA, Freeman KB. Obituary: William L. Woolverton. Psychopharmacology (Berl). 2013; 229(2):379-81. | 2013 |
| Riley AL, Freeman KB. Conditioned taste aversion: A database Pharmacology, Biochemistry and Behavior. 2004 ;77(3):655-6. | 2004 |
| Riley AL, Freeman KB. Conditioned flavor aversions: assessment of drug-induced suppression of food intake. Current Protocols in Neuroscience. 2004; Chapter 8:Unit 8.6E. | 2004 |
Review Article | |
| Zhou, Y., Freeman, K.B., Setola, V., Cao, D., Kaski, S., Kreek, M.J., Liu-Chen, L. Preclinical studies of nalfurafine (TRK-820), a clinically used KOR agonist Handbook of Experimental Pharmacology. 2021; epub ahead of print. | 2021 |
| Perkins FN, Freeman KB Pharmacotherapies for decreasing maladaptive choice in drug addiction: Targeting the behavior and the drug Pharmacology, Biochemistry, and Behavior. 2017; In Press | 2018 |
| Huskinson SL, Naylor JE, Rowlett JK, Freeman KB. Predicting abuse potential of stimulants and other dopaminergic drugs: overview and recommendations Neuropharmacology. 2014; 87:66-80 | 2014 |
Dissertation | |
| Freeman KB Assessment of noradrenergic mediation in the aversive effects of cocaine | 2007 |
Book Chapter | |
| Freeman KB, Riley AL The Origins of Conditioned Taste Aversion Learning: A Historical Analysis Conditioned Taste Aversion: Behavioral and Neural Processes. Oxford University Press. pp. 9-33 | 2009 |
| Freeman KB, Riley AL. The Conditioned Taste Aversion Preparation: Practical Applications and Technical Considerations. Tasks and Techniques: A Sampling of the Methodologies for the Investigation of Animal Learning, Behavior and Cognition. Nova Science Publishers. pp. 125-138 | 2006 |
Presentations
| Oral presentation, Typical and atypical kappa opioid agonists reduce cocaine and oxycodone choice in a drug vs. food self-administration model in male rhesus monkeys, CPDD, Virtual meeting | 06/2021 |
| Oral presentation, Comparison of the reinforcing and antinociceptive effects of prototypical and G-protein “biased” mu-opioid receptor agonists in male and female Sprague-Dawley rats, ISGIDAR, Virtual meeting | 06/2021 |
| Regional Invited Seminars/Lectures, Pain management for dental professionals in the era of the opioid crisis, Eastern Mississippi Dental Association, Meridian, MS | 05/2021 |
| State/Local Invited Seminars/Lectures, Atypical kappa opioid receptor agonists as deterrents for prescription opioid abuse, UMMC - NAS, Jackson, MS | 02/2021 |
| Poster Presentation, Quantification of the relative potencies of mu opioid receptor agonists of varying G-protein signaling bias in a rat model of thermal antinociception, BBC, San Antonio, TX | 03/2020 |
| Poster Presentation, Antinociceptive effects of G-protein biased mu opioid receptor agonists in male and female rats with chemotherapy-induced neuropathy, BBC, San Antonio, TX | 03/2020 |
| Poster Presentation, Enhancement of oxycodone-induced antinociception with kappa opioid receptor agonists in rats: assessment of the role of G-protein bias at the kappa receptor, BBC, San Antonio, TX | 03/2020 |
| National and International Invited Seminars/Lectures, Atypical kappa opioid receptor agonists as deterrents for prescription opioid abuse, Johns Hopkins University, Baltimore, MD | 11/2019 |
| Oral presentation, Nalfurafine blocks oxycodone’s conditioned rewarding effects and acquisition of oxycodone self-administration in male rats, CPDD, San Antonio, TX | 06/2019 |
| Oral presentation, Quantification of observable behaviors induced by kappa agonists in rhesus monkeys: Effects of signaling bias, CPDD, San Antonio, TX | 06/2019 |
| Oral communication, Delay discounting of food and cocaine in male rhesus monkeys, ABAI, Chicago, IL | 05/2019 |
| Oral presentation, Kappa-opioid agonists: Assessment of signaling bias on antinociception and oxycodone self-administration reduction in rats, BBC, San Antonio, TX | 03/2019 |
| State/Local Invited Seminars/Lectures, Causes of and countermeasures for the opioid crisis, Northeast Jackson Rotary Club, Jackson, MS | 2019 |
| Poster Presentation, Variability as a determinant of food and cocaine choice in rhesus monkeys, ABAI, Washington, D.C. | 11/2018 |
| Oral presentation, Oxycodone self-administration on a progressive-ratio schedule is reduced by contingent administration of the atypical kappa-opioid agonist, nalfurafine, in rhesus monkeys, CPDD, San Diego, CA | 06/2018 |
| Poster Presentation, Behavioral profile of mu and kappa-opioid agonists in male rhesus monkeys, CPDD, San Diego, CA | 06/2018 |
| Poster Presentation, Administration of KRM-II-81, an α-1sparing GABA receptor ligand, exhibits decreased respiratory depressing effects compared to alprazolam, BBC, San Antonio, TX | 03/2018 |
| Oral presentation, Assessment of the kappa-opioid agonist, nalfurafine, on the reinforcing and antinociceptive effects of oxycodone in male and female rats, BBC, San Antonio, TX | 03/2018 |
| Poster Presentation, The biased mu-opioid agonist, TRV130, produces reinforcing and antinociceptive effects that are comparable to oxycodone in rats., BBC, San Antonio, TX | 02/2018 |
| State/Local Invited Seminars/Lectures, From Pill to Needle: Targeting the Pipeline of the Prescription Opioid Epidemic, Dept. Psychiatry and Human Behavior, UMMC | 09/2017 |
| Oral Presentation, Effects of nalfurafine on oxycodone reinforcement and thermal antinociception: Modeling a candidate abuse-deterrent opioid in male rats, CPDD, Montreal | 06/2017 |
| Oral Presentation, Comparison of the punishing effects of nalfurafine and salvinorin A on cocaine and oxycodone self-administration in rhesus monkeys, CPDD, Montreal | 06/2017 |
| Oral Presentation, Nalfurafine decreases the reinforcing effects of oxycodone while producing additive thermal antinociception in male rats, Kappa Therapeutics, Philadelphia, PA | 04/2017 |
| Oral Communication, Reinforcing and antinociceptive effects of oxycodone and nalfurafine mixtures in male rats, BBC, San Antonio, TX | 03/2017 |
| Poster Presentation, Use of mu opioid antagonists and pharmacological punishers in the development of abuse-deterrent opioid analgesics, Am Soc Health-System Pharmacists, Las Vegas, NV | 12/2016 |
| Poster Presentation, Novel environment response as a predictor of midazolam self-administration in rats, CPDD, Montreal | 06/2016 |
| Poster Presentation, Comparison of cocaine reinforcement in lean and obese Zucker rats: Dose-sensitivity and reinstatement of extinguished operant responding., College on Problems of Drug Dependence | 06/2015 |
| Oral Presentation, Self-administration of second-generation synthetic cathinones in rats., College on Problems of Drug Dependence | 06/2015 |
| Poster Presentation, Unpredictable availability as a determinant of cocaine choice., College on Problems of Drug Dependence | 06/2015 |
| Poster Presentation, Unpredictable availability as determinant of cocaine choice in rhesus monkeys., Association for Behavioral Analysis International | 05/2015 |
| Poster Presentation, Hippocampal volume is associated with verbal memory performance in older, but not younger, adults., Society for Neuroscience | 10/2014 |
| Poster Presentation, A procedure for rapid determination of delay discounting of drug and nondrug reinforcers in monkeys., College on Problems of Drug Dependence | 06/2014 |
| Oral Communication, Self-administration of oxycodone alone or as a mixture with the kappa agonist, salvinorin A, by monkeys under a progressive-ratio schedule of reinforcement., College on Problems of Drug Dependence | 06/2014 |
| Invited Symposia, Punishment of drug choice: Insights from the study of drugs as punishers., College on Problems of Drug Dependence | 06/2014 |
| Invited Symposia, The use of choice procedures to understand drug mixtures., Experimental Biology | 04/2014 |
| Poster Presentation, Delay discounting by monkeys in a drug vs. non-drug choice paradigm., College on Problems of Drug Dependence | 06/2013 |
| Poster Presentation, The kappa agonist, salvinorin A, punishes remifentanil and cocaine self-administration in monkeys., College on Problems of Drug Dependence | 06/2013 |
| Poster Presentation, Corn oil is a more effective reinforcer in obese than in lean Zucker rats., Association of Behavior Analysis International | 05/2013 |
| Poster Presentation, Assessment of the kappa agonist, salvinorin A, as a punisher of cocaine and remifentanil self-administration., Behavior, Biology and Chemistry | 03/2013 |
| Poster Presentation, Discounting by monkeys in an allomorphic choice paradigm: Immediate vs. delayed food., College on Problems of Drug Dependence | 06/2012 |
| Poster Presentation, Histamine mixed with cocaine reduces the reinforcing effectiveness of cocaine in rhesus monkeys., Behavioral Pharmacology Society | 04/2012 |
| Poster Presentation, Maintenance on an energy-dense “cafeteria diet” reduces the reinforcing effectiveness of corn oil but not saccharin in rats., Experimental Biology | 04/2012 |
| Poster Presentation, D2 receptor partial agonists: defining the association between intrinsic efficacy and reinforcing properties in monkeys, College on Problems of Drug Dependence | 06/2011 |
| Poster Presentation, Punishment of cocaine choice: effects of delaying punishment, College on Problems of Drug Dependence | 06/2011 |
| Poster Presentation, Self-administration of cocaine and remifentanil by monkeys under concurrent access conditions, College on Problems of Drug Dependence | 06/2011 |
| Oral Communication, The choice between cocaine-remifentanil and either drug alone: Increasing mixture dose, College on Problems of Drug Dependence | 06/2010 |
| Poster Presentation, Self-administration of cocaine, remifentanil, and cocaine-remifentanil mixtures by rhesus monkeys, Amer. College of Neuropsychopharmacology | 12/2009 |
| Oral Communication, Self-administration of cocaine and nicotine mixtures by rhesus monkeys, Behavioral Pharmacology Soc. Conference | 04/2009 |
| Oral Communication, Delay discounting of saccharin in rhesus monkeys, College on Problems of Drug Dependence Conference | 06/2008 |
| Poster Presentation, Noradrenergic antagonism enhances cocaine-induced conditioned taste aversion, Soc. for Neuroscience Conference | 11/2007 |
| Oral Communication, Differential patterns of cocaine self-administration under extended access conditions in Fischer and Lewis rats, International Study Group Investigating Drugs As Reinforcers Conference | 06/2006 |
| Poster Presentation, Assessment of monamine transporter inhibition in the mediation of cocaine-induced conditioned taste aversion, Soc. for Neuroscience Conference | 11/2005 |
| Poster Presentation, Assessment of the contribution of Na+ channel inhibition and general peripheral action in cocaine-induced taste aversion., College on Problems of Drug Dependence Conference | 06/2005 |
| Oral Communication, Cocaine-induced conditioned taste aversions over extended CS-US intervals, Soc. for Neuroscience Conference | 10/2004 |
Honors, Awards, and Recognition
| Trailblazer Teaching Award, UMMC | 2021 |
| Excellence in Research Award - Gold, University of Mississippi Medical Center (Jackson, MS) | 2017 |
| Excellence in Research Award - Silver, University of Mississippi Medical Center (Jackson, MS) | 2016 |
| Early Career Investigator Award, University of Mississippi Medical Center (Jackson, MS) | 2015 |
| Maharaj Ticku Travel Fellowship Award to attend and present an abstract at the 2013 annual meeting (San Antonio, TX), Behavior, Biology, and Chemistry (BBC) | 2013 |
| Travel Award to attend and present an abstract at the 2010 annual meeting (Scottsdale, AZ), College on Problems of Drug Dependence (CPDD) | 2010 |
| Robert M. Hearin Post-Doctoral Fellowship Award, University of Mississippi Medical Center (Jackson, MS) | 2007 |
| Student Award for Outstanding Scholarship at the Graduate Level, American University (Washington, DC) | 2006 |
| College of Arts and Sciences Dissertation Award, American University (Washington, DC) | 2006 |
| College of Arts and Sciences Merit Scholarship, American University (Washington, DC) | 2003 |
| Psi Chi (Psychology Honor Society), University of Mississippi (Oxford, MS) | 2000 |
Professional Membership and Service
| American Psychological Association, Member | 2020 - Present |
| American Society for Pharmacology and Experimental Therapeutics, Member | 2014 - Present |
| Behavioral Pharmacology Society, Member | 2009 - Present |
| College on Problems of Drug Dependence, Member | 2008 - Present |
| International Study Group Investigating Drugs as Reinforcers, Member | 2008 - Present |
| Society for Neuroscience, Member | 2005 - Present |
Committee Service
| Program Committee - College on Problems of Drug Dependence (CPDD), Chair | 2021 - 2025 |
| Study section - NIH/NIMH Conte P50 panel, Member | 2020 - Present |
| Study section - NIH/NIDA RFA Panel, Member | 2020 - Present |
| Discovery Curriculum Subcommittee, Member | 2020 - Present |
| MEDICAL CENTER-ANIMAL CARE AND USE, Based on my performance during a 5-year term (2012-2017), I was asked to serve as an alternate beginning in 2020 to provide expert review on an as-needed basis. | 2020 - Present |
| Committee on Animal Research and Ethics - American Psychological Association, Chair | 2020 - 2022 |
| Study section - NIH RFA panel, Member | 2019 - Present |
| SCHOOL OF MEDICINE-RESIDENCY REVIEW SUBCOMMITTEE, Member | 2018 - 2020 |
| Study section - Veteran's Administration; RRDA, Spinal Cord Injury, Disorder, and Pain Panel, Member | 2017 - Present |
| Study section: Uniformed Services University, Military Women's Health Research Committee, Member | 2017 - Present |
| Inclusion of Basic Science Committee -- CPDD, Member | 2017 - 2017 |
| Mississippi Department of Mental Health, Bureau of Alcohol and Drug Services Advisory Council, Member | 2016 - Present |
| Program Committee - College on Problems of Drug Dependence (CPDD), Member | 2016 - 2019 |
| COBRE Grant Review - Center for Psychiatric Neuroscience, Ad Hoc Reviewer | 2015 - Present |
| The Program in Neurosciences Executive Committee, Member | 2013 - 2015 |
| MEDICAL CENTER-ANIMAL CARE AND USE, Member | 2012 - 2017 |
| Neuroscience Summer Scholars Selection Committee, Member | 2011 - 2011 |
| Intramural Research Support Program Review Committee, Ad Hoc Reviewer | 2011 - 2013 |
| Faculty Merit Committee, American University, Graduate Student representative | 2004 - 2005 |
Community Service
| Gave a talk on rising polydrug-abuse trends for the Bureau of Alcohol and Drug Services, Mississippi Department of Mental Health, Jackson, MS, Speaker | 08/2021 - Present |
| Gave a talk on the impact of abuse-deterrent formulations on prescription opioid abuse for the Mississippi Association of Drug Court Professionals, Tupelo, MS, Speaker | 08/2016 - Present |
| Gave a talk on the impact of abuse-deterrent formulations on prescription opioid abuse for the State Epidemiological Outcomes Workgroup, Mississippi Department of Mental Health, Jackson, MS, Speaker | 05/2016 - Present |
| Gave a talk on synthetic drugs of abuse ("spice" and "bath salts") for the Office of Tobacco Control, Mississippi State Department of Health, Speaker | 11/2015 - Present |
| Gave a talk on synthetic drugs of abuse ("spice" and "bath salts") for the Neuroscience Seminar Series at Millsaps College, Jackson, MS, Speaker | 10/2015 - Present |
| Gave a talk on addiction research and its health implications to an assembly of the high school student body at St. Andrews, Ridgeland, MS, Speaker | 03/2014 - Present |
| Gave a talk on the science of drug abuse research. "Science Literacy Lecture Series" at St. Andrews, Ridgeland, MS, Speaker | 02/2013 - Present |
| Gave a talk on the science of drug and food addiction for the Neuroscience Seminar Series at Millsaps College, Jackson, MS, Speaker | 10/2011 - Present |
| Conducted a NIDA-sponsored seminar on drug abuse at Rosa Scott Middle School, Madison, MS, Speaker | 11/2010 - Present |
Other Service
| Scientific Reports | |
| Neuropsychopharmacology | |
| Journal of Pharmacology and Experimental Therapeutics | |
| Neuroscience | |
| Addiction Biology | |
| Behavioral Pharmacology | |
| Drug and Alcohol Dependence | |
| Pharmacology, Biochemistry and Behavior | |
| Physiology & Behavior | |
| Psychopharmacology |
Teaching Experience
| NSCI701, Graduate, Course, Lecturer, Foundations of Neuroscience | Spring 2021 |
| NSCI708, Graduate, Small Group, Facilitator, Special Topics in Neuroscience | Summer 2021 |
| NSCI710, Graduate, Course, Lecturer, Statistics | Spring 2021 |
| Medicine, Course, Course Director, Resident Scholarship Program | Annual 2021 |
| NSCI721A, Graduate, Course, Course Director, Scientific Writing | Fall 2021 |
| NSCI708, Graduate, Small Group, Facilitator, Special Topics in Neuroscience | Summer 2020 |
| NSCI710, Graduate, Course, Lecturer, Statistics | Spring 2020 |
| Medicine, Course, Course Director, Resident Scholarship Program | Annual 2020 - 2021 |
| NSCI721A, Graduate, Course, Course Director, Scientific Writing | Fall 2020 - 2020 |
| NSCI701, Graduate, Course, Lecturer, Foundations of Neuroscience | Spring 2020 |
| NSCI710, Graduate, Course, Lecturer, Statistics | Spring 2019 |
| Medicine, Course, Course Director, Resident Scholarship Program | Annual 2019 - 2020 |
| NSCI721A, Graduate, Course, Course Director, Scientific Writing | Fall 2019 - 2019 |
| NSCI701, Graduate, Course, Section Director, Foundations of Neuroscience | Spring 2019 |
| NSCI708, Graduate, Small Group, Facilitator, Special Topics in Neuroscience | Summer 2018 |
| NSCI710, Graduate, Course, Lecturer, Statistics | Spring 2018 |
| NSCI701, Graduate, Course, Section Director, Foundations of Neuroscience | Spring 2018 |
| Neuroscience 701, Graduate, Course, Section Director, Foundations of Neuroscience | Spring 2017 |
| NSCI 710, Graduate, Lecture, Lecturer, Tutorials in Neuroscience | Spring 2017 |
| NSCI708, Graduate, Small Group, Facilitator, Special Topics | Summer 2017 |
| Neuroscience 701, Graduate, Lecture, Lecturer, Foundations of Neuroscience | Spring 2017 |
| Biomedical Sci 727, Medicine, Lecture, Lecturer, Current Issues in Biomedical Research and Translational Medicine | Fall 2017 |
| Psych 631, Medicine, Small Group, Facilitator, Clerkship for Medical Students | Annual 2017 |
| NSCI 710, Graduate, Lecture, Lecturer, Tutorials in Neuroscience | Spring 2016 |
| Neuroscience 701, Graduate, Lecture, Lecturer, Foundations of Neuroscience | Spring 2016 |
| Biomedical Sci 727, Medicine, Lecture, Lecturer, Current Issues in Biomedical Research and Translational Medicine | Fall 2016 |
| Psych 631, Medicine, Small Group, Facilitator, Clerkship for Medical Students | Annual 2016 - 2019 |
| Neuroscience 701, Graduate, Course, Section Director, Foundations of Neuroscience | Spring 2016 |
| Neuroscience 701, Medicine, Lecture, Lecturer, Foundations of Neuroscience | Spring 2015 |
| Biomedical Sci 727, Medicine, Lecture, Lecturer, Current Issues in Biomedical Research and Translational Medicine | Spring 2015 |
| Neuroscience 701, Graduate, Course, Section Director, Foundations of Neuroscience | Spring 2015 |
| Psych 631, Medicine, Small Group, Facilitator, Clerkship for Medical Students | Annual 2015 |
| Neuroscience 701, Graduate, Lecture, Lecturer, Foundations of Neuroscience | Spring 2014 |
| Biomedical Sci 727, Medicine, Lecture, Lecturer, Current Issues in Biomedical Research and Translational Medicine | Spring 2014 |
| Neuroscience 701, Graduate, Course, Section Director, Foundations of Neuroscience | Spring 2014 |
| Biomedical Sci 727, Graduate, Lecture, Lecturer, Current Issues in Biomedical Research and Translational Medicine | Spring 2013 |
| Biomedical Sci 727, Graduate, Lecture, Lecturer, Current Issues in Biomedical Research and Translational Medicine | Spring 2012 |
| NSCI 706, Graduate, Lecture, Lecturer, CNS Pharmacology | Annual 2008 - 2013 |
Directed Student Learning
| Supervised Research, Advised: Rose Le | 2021 - 2021 |
| Supervised Research, Advised: Haley Rooks | 2021 - 2021 |
| Doctoral Advisory Committee Chair, Advised: Shelly Rae Edwards | 2021 - Present |
| Supervised Research, Advised: Ricardo Ungo | 2021 - Present |
| Doctoral Advisory Committee Chair, Advised: Loc Pham | 2020 - Present |
| Supervised Research, Advised: Hina Qureshi | 2020 - 2020 |
| Supervised Research, Advised: Heather Hembree | 2019 - 2019 |
| Supervised Research, Advised: Hayley Schrock | 2019 - Present |
| Dissertation Defense Committee Member, Advised: Sydney Vita | 2017 - 2020 |
| Dissertation Committee Chair, Behavioral pharmacology of G-protein biased mu and kappa opioid receptor agonists: Abuse liability, antinociception, and respiratory depression. Advised: Austin Zamarripa | 2017 - 2021 |
| Supervised Research, Advised: John Yi | 2017 - 2020 |
| Doctoral Advisory Committee Member, Advised: Xiao Zhang | 2016 - 2019 |
| Supervised Research, Advised: Tilak Patel | 2016 - 2020 |
| Supervised Research, Advised: Hunter McClendon | 2016 - 2019 |
| Dissertation Committee Member, Preclinical investigation of novel Salvinorin A analogues for the treatment of drug addiction Advised: Amy Ewald | 2015 - 2016 |
| Doctoral Advisory Committee Member, Advised: Cassie Chandler | 2015 - 2018 |
| Dissertation Committee Member, Evaluation of the abuse-related and anxiolytic-like effects of benzodiazepine and neuroactive steroid combinations in rats. Advised: Barak Gunter | 2013 - 2015 |
| Dissertation Committee Chair, Assessment of the effects of kappa opioid agonists on oxycodone's therapeutic and abuse-related effects. Advised: Jennifer Naylor | 2013 - 2015 |
| Dissertation Committee Chair, Effects of nalfurafine on the abuse-related and antinociceptive effects of oxycodone in rats and rhesus monkeys Advised: Drew Townsend | 2012 - 2017 |
| Dissertation Committee Member, Human hippocampal volume and its possible rose as an early life biomarker for cognitive decline. Advised: Mike Schmidt | 2011 - 2016 |
Fellows supervised
| Psychiatry, Research Advisor, 1 fellows supervised | 07/2012 - 04/2017 |
Residency Training
| Resident Scholarship Program, Research Advisor | 2019 - 07/2020 |
| Resident Scholarship Program, Program Director | 2019 - Present |
| Psychiatry Residency, Research Advisor | 2016 - 05/2017 |