John J. Correia, PhD

John J. Correia, PhD

Professor Emeritus

Department:
SOM-Cell and Molecular Biology

Email:
jcorreia@umc.edu

Work Phone:
(601) 984-1522

Education

University of Connecticut, Storrs, CT, PhD, Biophysics1981
Vanderbilt University, Postgraduate Training, Microtubule Biochemistry1981
Villanova University, Villanova, PA, BA, General Science1972

Current Positions

Professor, School of Medicine, Department of Biochemistry07/1997 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Associate Professor, The University of Mississippi Medical Center, School of Medicine, Department of Biochemistry07/1992 - 06/1997
Assistant Professor, The University of Mississippi Medical Center, School of Medicine, Department of Biochemistry11/1987 - 06/1992

Sponsored Program Funding

Extramural, Systems Biology of Antimitotic Drugs and Chemotherapy, Charles Morgan Carraway and Joanne M. Carraway Charitable Foundation04/2007 - 03/2008
Extramural, Structural Basis of Regulation of Interferon Regulatory Factor, NIH, 1 RO1 - PI: Kai Lin at U Mass Medical School07/2004 - 01/2008
Extramural, Development of AUC Fluorescence Methods for Hetero-Protein Interactions, BITC (Biomolecular Interaction Technologies Center @ Univ. of NH)05/2004 - 04/2006
Extramural, Basis of Phosphorylation in TGF- Signaling., NIH, 1 RO1 CA81106-01A2 -PI: Kai Lin at U Mass Medical School07/2003 - 06/2004
Extramural, "Interaction of Antimitotics with Tubulin Isotypes, NSF05/1993 - 04/1998
Extramural, "Dynamics of Microtubule Assembly/Disassembly, NIH12/1988 - 11/1993

Publications

Journal Article

P. Holland Alday and John J. Correia "Macromolecular Interaction of Halichondrin B analogs Eribulin (E7389) and ER-076349 with Tubulin by Analytical Ultracentrifugation." Biochemistry, 48, 7927-7938.2009
CORREIA, J. J., Alday, P.H., Sherwood, P. and Stafford, W. F. Effect of Kinetics on Sedimentation Velocity Profiles and the Role of Intermediates. Ed. Michael L. Johnson) Vol 467, Numerical Methods, 467:135-612009
Steven S. Rosenfeld, Marilyn Van Duffelen, Will Parks, Christopher Beadle, John J. Corrreia, and Jun Xing THE ATPase Cycle of the Mitotic Motor CENP-E. JBC, 284, 32858–32868.2009
George J. Turner, Shirisha Chittiboyina, Lauren Pohren, Kirk G. Hines, John J. Correia, and The Bacteriorhodopsin Carboxyl-Terminus Contributes to Proton Recruitment and Protein Stability. Biochemistry. 2009; in press2009
Weijun Chen, Suvana S. Lam, Hema Srinath, Zhaozhao Jiang, John J CORREIA, Celia A. Schiffer, Katherine A. Fitzgerald, Kai Lin & William E. Royer Jr. Interferon regulatory factor activation revealed by the crystal structure of dimeric IRF-5 Nature Structural & Molecular Biol. 2008; 15, 1213-12202008
Ashish Aggarwal, Anna Kruczynski, Anthony Frankfurter, John J. CORREIA and Sharon Lobert Murine Leukemia P388 Vinorelbine-Resistant Cell Lines Are Sensitive to Vinflunine Investigational New Drugs. 2008; 26, 319-3302008
Valeria Cucchiarelli, Laree Hiser, Hilda Smith, Anthony Frankfurter, Anthony Spano, β-Tubulin Isotype Classes II and V Expression Patterns in Nonsmall Cell Lung Carcinomas. Cell Motil. Cytoskel. 2008; 65, 675-6852008
S. S. Dignam, J. J. CORREIA, S. A. Nada, J. P. Trempe, J. D. Dignam Activation of the ATPase Activity of Adenoassociated Virus Rep68 and Rep78 Biochemistry. 2007; 46: 6364-63742007
Montserrat Bosch, Kim Ho Diep Le, Beata Bugyi, John J. CORREIA, Louis Renault and Marie-France Carlier Analysis of the function of Spire in actin assembly and its synergy with formin and profiline Mol Biol Cell. 2007; 28:555-682007
Anthony J. Spano, Frank S. Chen, Benjamin E. Goodman, Agnes E. Sabat, Martha N. Simon, Joseph S. Wall, John J. CORREIA, Wilson McIvor, William W. Newcomb, Jay C. Brown, Joel M. Schnur and Nikolai Lebedev In vitro assembly of a Prohead-like Structure of Rhodobacter capsulatus Gene Transfer Agent. Virology. 2007; 364: 95-1022007
S. Lobert, J.W. Ingram and J.J. CORREIA The Thermodynamics of Vinca Alkaloid-Induced Tubulin Spiral Formation. Biophys. Chem. 2007; Special Issue, Festschrift for Julian Sturtevant, 126: 50-58.2007
S. Lobert and J.J. CORREIA “Methods for studying vinca alkaloid interaction with tubulin .” Humana Press, (Ed., Jin Zhou), Chapter 18, pp 261-280.2007
L. Hiser, A. Aggarwal, R. Young, A. Frankfurter, A, Spano, J. J. CORREIA, and S. Lobert, “Correlation of Beta-Tubulin mRNA and Protein Levels in Twelve Human Cancer Cell Lines” Cell Motility & Cytoskeleton, 63, 41.2006
B. Qin, C. Liu, H. Srinath, S. S. Lam, J. J. CORREIA, R. Derynck, K. Lin, Crystal Structure of IRF-3 in Complex with CBP Structure, 13, 1-9.2005
. J. CORREIA, C. A. Sontag, W. F. Stafford and P. J. Sherwood, “Models for Direct Boundary Fitting of Indefinite Ligand-Linked Self-Association” in Analytical Ultracentrifugation: Techniques and Methods. (Ed. D. Scott, S. Harding and A. Rowe) pp 51-63.2005
J. Li, J. J. CORREIA, L. Wang, J. O. Trent & J. B. Chaires “Not So Crystal Clear: The Structure of the Human Telomere G-quadruplex in Solution Differs from that Seen in the Crystal2005
A.T. Mackey, C.A. Sontag, L.L. Satterwhite, J.J. CORREIA, and Susan P. Gilbert, “The ATPase Mechanism Behind the Microtubule-Based Motility of GST-Kar3” JBC, 279, 51354-61.2004
A.T. Mackey, C.A. Sontag, L.L. Satterwhite, J.J. CORREIA, and Susan P. Gilbert “The ATPase Mechanism Behind the Microtubule-Based Motility of GST-Kar3” JBC, 279, 51354-61.2004
CORREIA, J. J., and Stafford, W. F. (2009) Extracting equilibrium constants from kinetically limited reacting systems. (Ed. Michael L. Johnson) Vol 455, Biothermodynamics, Part A, pp. 419-46

Review Article

M.A. Jordan, S.B. Horowitz, S. Lobert, J.J. CORREIA Exploring the Mechanisms of Action of the Novel Microtubule Inhibitor Vinflunine. Seminars in Oncology. 2208; 35, S6-S122008

Thesis

J.J. CORREIA Analytical Ultracentrifuge Techniques for Unstable Protein Systems PhD Thesis, University of Connecticut1981

Book Chapter

J. J. CORREIA and S. Lobert Molecular Mechanisms of Micotubule Acting Cancer Drugs in Microtubule Targets in Cancer Therapy, Humana Press (Ed., Tito Fojo) 20082008
S. Lobert and J.J. CORREIA Methods for studying vinca alkaloid interaction with tubulin. Humana Press, (Ed., Jin Zhou), Chapter 18, pp 261-2802007

Presentations

"The use of AUC (Analytical Ultracentrifugation) to characterize drug delivery systems." October, 12 2012., Mississippi State University, Department of Chemistry10/2012
Scientific Presentations, "FDS Hydrodynamic Characterization of an Elastin-Like Drug Delivery Peptide in Plasma." April 13, 2012., Notre Dame University, Department of Chemistry and Biochemistry04/2012
Scientific Presentations, "FDS Hydrodynamic Characterization of an Elastin-Like Drug Delivery Peptide in Plasma." Dec 1, 2011, Univ Colorado Anschutz Medical Campus, Department of Pharmaceutical Sciences12/2011
National and International Invited Seminars/Lectures, Introduction to session on Biothermodynamics and Disease: From Free Energy to the Clinic, 25th Gibbs Conference on Biothermodynamics09/2011
National and International Invited Seminars/Lectures, UMC Biochemistry Retreat, Jackson, MS09/2011
National and International Invited Seminars/Lectures, FDS Hydrodynamic Characterization of an Elastin-Like Drug Delivery Peptide in Plasma, UNH AUC Workshop, Durham, UNH07/2011
National and International Invited Seminars/Lectures, The Use of Fluorescence Detection in AUC studies: Advantages and Challenges, Mississippi Biophysical Consortium, Oxford, MS06/2011
National and International Invited Seminars/Lectures, Progress on the Biophysics of Anti-Cancer Drugs, UMMC, Department of Biochemistry11/2010
National and International Invited Seminars/Lectures, The Use of Fluorescence Optics in Analytical Ultracentrifugation Studies: A Goal of In Vivo Biophysics, University Southern Mississippi10/2010
National and International Invited Seminars/Lectures, The Use of Simulations in Understanding AUC Analysis Methods, BBRI AUC Workshop, Boston, MA05/2010
National and International Invited Seminars/Lectures, Simulation and Investigation of Macromolecular Interactions by AUC: Drugs, Kinetics and Fluorescence Detection, Johns Hopkins University, Baltimore, MD05/2010
National and International Invited Seminars/Lectures, Macromolecular Interaction of Halichondrin B Analogues Eribulin (E7389) and ER-076349 with Tubulin by Analytical Ultracentrifugation, 125th The Svedberg Anniversary, 18th International AUC Conference, Uppsala, Sweden09/2009
National and International Invited Seminars/Lectures, Anti-Mitotic Drugs: Do In Vitro Measurements Translate to In Vivo Mechanisms, University of Colorado, Boulder, CO05/2009
National and International Invited Seminars/Lectures, Energetics, Regulation and Modeling of Mitotic Microtubule Complexes: Windows into the Biology of Anti-Mitotic Drugs, Medical College of South Carolina, Charleston, SC04/2008
Scientific Presentations, Energetics, Regulation and Modeling of Mitotic Microtubule Complexes: Windows into the Biology of Anti-Mitotic Drugs., Medical College of South Carolina, Medical College of South Carolina, Charleston, SC04/2008
National and International Invited Seminars/Lectures, How to Integrate Clinical Correlations into Medical Biochemistry, Medical Biochemistry Education Strategies Workshop, Myrtle Beach, SC04/2008
National and International Invited Seminars/Lectures, Energetics, Regulation and Modeling of Mitotic Microtubule Complexes, RASMB Gordon Research Conference, Ventura, CA01/2008
National and International Invited Seminars/Lectures, Vinflunine microtubule binding/ microtubule dynamics, Vinflunine Basic Science Summit, hosted by Bristol-Myers Squibb and Pierre Fabre Oncology, Paris, France03/2007
National and International Invited Seminars/Lectures, Comparative AUC Studies on Tubulin:Stathmin and Actin:Spire Complexes, CNRS, Gif sur Yvette, France03/2007
National and International Invited Seminars/Lectures, The Effect of Kinetics on Sedimentation Velocity Profiles: The Role of Intermediates, 15th International AUC Workshop and Symposium, University College London04/2006
National and International Invited Seminars/Lectures, E7389 suppresses Tubulin assembly and binding of Stathmin: biophysical characterization by quantitative sedimentation velocity, Eisai, Andover, MA03/2006
National and International Invited Seminars/Lectures, The Use of Multi-wavelength and Fluorescence AUC: Case Studies of Tubulin Regulatory Factors and Antimitotic Drugs, 19th Gibbs Conference on Biothermodynamics10/2005
National and International Invited Seminars/Lectures, The Use of Muti-wavelength and Fluorescence AUC in Drug Discovery: Studies on Tubulin, Regulatory Factors and Antimitotic Drugs, Louisville University08/2005
National and International Invited Seminars/Lectures, Interaction of Stathmin-Tubulin-Vinblastine by Multi-wavelength and Fluorescence AUC Techniques, EMBL, Heidelberg, Germany06/2005
National and International Invited Seminars/Lectures, The Mechanism of Action of AntiMitotic Drugs: Implications for Drug Discovery, Department Pharmacognosy, Univ of Mississippi, Oxford, MS04/2005
National and International Invited Seminars/Lectures, The Use of XLA- and XLF-AUC Techniques to Dissect the Energetics of Tight Interactions Between Tubulin, Drugs and Regulatory Proteins, Amgen, Los Angeles, CA01/2005
National and International Invited Seminars/Lectures, The Use of Fluorescence Optics to Investigate Interactions Between Tubulin, Regulatory Factors and Anti-Mitotc Drugs, BITC annual meeting, Los Angeles, CA01/2005
National and International Invited Seminars/Lectures, The Use of Multi-Wavelength and Fluorescence AUC Techniques to Measure the Energetics of Tight Interactions Between Tubulin, Drugs and Regulatory Proteins, UC Santa Barbara01/2005
National and International Invited Seminars/Lectures, Direct Boundary Fitting of Hetero-Association, Finally!, NAUCF Workshop Symposium, Storrs, CT06/2004
National and International Invited Seminars/Lectures, Direct Boundary Fitting of Indefinite Ligand-Linked Self-Association: New Insights, European UK AUC meeting, Oxford, UK04/2004
National and International Invited Seminars/Lectures, Quantifying Ternary Interactions Between Antimitotic Drugs, Tubulin and Regulatory Proteins: A Window on Drug Resistance, The University of Texas Medical Branch, Galveston, TX03/2004
National and International Invited Seminars/Lectures, Model Building and Analysis Methods for Indefinite Associating Systems, NAUCF Workshop Symposium, Storrs, CT06/2003
National and International Invited Seminars/Lectures, Do Tubulin Drugs Disrupt or Mimic Interactions with Regulatory Factors Through Ternary Complex Formation?, Madrid, Spain, CIB05/2003
National and International Invited Seminars/Lectures, Using AUC to Study Anti-Mitotic Drugs and the Microtubule Interactome, NAUCF Workshop Symposium, Storrs, CT06/2002
National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets.” Or “Antimitotic Drugs and New Targets: From Biophysics to Cellular Effectiveness, Department of Cell Biology and Biophysics, University of Missouri - Kansas City04/2002
National and International Invited Seminars/Lectures, The Regulation and Energetics of Receptor Mediated Smad Trimerization, 15th Gibbs Conference on Biothermodynamics09/2001
National and International Invited Seminars/Lectures, Tall Tales about the Power of the Almighty Analytical Ultracentrifuge, NAUCF Workshop Symposium, in memory of Todd Schuster, Storrs, CT05/2001
National and International Invited Seminars/Lectures, Better (Anti-Cancer) Drugs Through (Bio)Chemistry, UMMC, Campus Research Seminar, Jackson, MS05/2001
National and International Invited Seminars/Lectures, What Can Fluorescent Vinca Alkaloids Teach Us?, Castres, France, Pierre Fabre04/2001
National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets, French-American Colloquium on the Cytoskeleton and Human Disease, Marseille, France04/2001
National and International Invited Seminars/Lectures, The Energetics of Antimitotic Drugs: New Approaches and New Targets, Structure/Function Seminar Series, Univ. Alabama Birmingham03/2001
National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets, Department of Pharmacology, Univ. of Mass. Med. School02/2001
National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets, Department of Molecular Biology and Molecular Biophysics Program Project Seminar Series, Vanderbilt University02/2001
National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets, Department of Biology, Georgia Tech, Atlanta, GA10/2000
National and International Invited Seminars/Lectures, The Interactions of Vinca Alkaloids with Tubulin and Microtubules: Biophysical Data and Implications for Cancer Chemotherapy, Dept Chemistry, Oxford, MS04/2000
National and International Invited Seminars/Lectures, The interaction of tubulin heterodimers with kinesin motor domains: methodology, nucleotide dependence & implications for microtubule dynamics, EMBL, Heidelberg, Germany03/1999
National and International Invited Seminars/Lectures, Energetics of Chemotherapeutic Vinca Alkaloids Through Analytical Ultracentrifugation: Implications for Drug Design, Wurzburger Symposium, University of Heidelberg, Heidelberg, Germany03/1999
National and International Invited Seminars/Lectures, New Techniques For The Analysis of Hetero-associating Systems, Analytical Ultracentrifuge Workshop at the NSF National Analytical Ultracentrifuge Facility, Univ. of Conn., Storrs, Ct03/1999
National and International Invited Seminars/Lectures, Energetics of Chemotherapeutic Vinca Alkaloids Through AUC: Implications for Drug Design, 2nd Beckman Symposium, Seattle, WA09/1998
National and International Invited Seminars/Lectures, The Interactions of Vinca Alkaloids with Tubulin and Microtubules: Biophysical Data and Implications for Cancer Chemotherapy, Miss State04/1998
National and International Invited Seminars/Lectures, Energetics of Vinca Alkaloid Tubulin and Tubulin Kinesin Motor Domain Interactions, Department of Pharmacology, UT - SW Medical Center03/1998
National and International Invited Seminars/Lectures, The Analysis of Interacting Systems by Sedimentation Velocity, Analytical Ultracentrifuge Workshop at the NSF National Analytical Ultracentrifuge Facility, Univ. of Conn., Storrs, Ct03/1998
National and International Invited Seminars/Lectures, Biophysical Studies of Vinca Alkaloid -Tubulin/Microtubule Interactions: Mechanistic and Clinical Implications, Univ. Of Miss. Medical Center, Department of Physiology and Biophysics02/1998
National and International Invited Seminars/Lectures, Analysis of Weight Average Sedimentation Velocity Data, 1st Beckman Symposium, Galveston, TX11/1997
National and International Invited Seminars/Lectures, The Use of Analytical Ultracentrifugation to Extract the Energetics of Vinca Alkaloid Tubulin Interactions, 3rd Annual Beckman Seminar, Univ. of Texas Health Science Center, San Antonio, TX.04/1997
National and International Invited Seminars/Lectures, Quantitative Interpretation of Weight Average Sedimentation Velocity Data, 10th Symposium on Analytical Ultracentrifugation, University of Regensberg, Regensberg, Germany03/1997
National and International Invited Seminars/Lectures, The Quantitative Interpretation of Weight Average Sedimentation Velocity Data, Analytical Ultracentrifuge Workshop at the NSF National Analytical Ultracentrifuge Facility, Univ. of Conn., Storrs, Ct03/1997
National and International Invited Seminars/Lectures, Sedimentation Studies on Kinesin and NCD Motor Domain Constructs, Biophysical Society Meeting, New Orleans, LA02/1997
National and International Invited Seminars/Lectures, Sedimentation Velocity Studies of the Vinca Alkaloid Induced Self Association of Tubulin, SPIE's International Symposium, BIOS'97, Biomedical Optics, San Jose, CA02/1997
National and International Invited Seminars/Lectures, Sedimentation Velocity Studies of the Vinca Alkaloid Induced Self Association of Tubulin and Tubulin Isotypes, 10th Annual Gibbs Conference on Biothermodynamics, Carbondale, Il10/1996
National and International Invited Seminars/Lectures, Sedimentation Velocity and Kinetic Studies on the Interaction of Vinca Alkaloids with Tubulin and B Tubulin Isotypes, Texas Medical Center, Houston, TX.04/1996
National and International Invited Seminars/Lectures, Interaction of Vinca Alkaloids with Tubulin, Analytical Ultracentrifuge Workshop at the NSF National Analytical Ultracentrifuge Facility, Univ. of Conn., Storrs, Ct03/1996
National and International Invited Seminars/Lectures, What Have Nonhydrolyzable GTP Analogs Taught us About Microtubule Assembly and Structure?, American Society for Cell Biology, Symposium on GTPases12/1995
National and International Invited Seminars/Lectures, The Interaction of Vinca Alkaloids with Tubulin by Analytical Ultracentrifugation, A meeting on The Cytoskeleton and Cancer, Ile des Embiez, France09/1995
National and International Invited Seminars/Lectures, The Interaction of Vinca Alkaloids with Tubulin by Analytical Ultracentrifugation: Clinical Implications, CNRS, Gif sur Yvette, France09/1995
National and International Invited Seminars/Lectures, Vinblastine Induced and Divalent Cation Induced Self Association of Tubulin and Tubulin Isotypes, Symposium on Analytical Ultracentrifugation, Berlin, Germany03/1995
National and International Invited Seminars/Lectures, Analytical Ultracentrifugation: A 'New' Technique for the Investigation of Macromolecular Association, Department of Biochemistry, University of Mississippi Medical Center02/1995
National and International Invited Seminars/Lectures, Microtubule Assembly and the Role of Nucleotides, Tubulin Isotypes, MAPs and Antimitotic Drugs, Department of Biochemistry, Louisiana St. School of Medicine, Shreveport, LA11/1994
National and International Invited Seminars/Lectures, The Interaction of Tubulin With Vanadate: Photoirradiation and Microtubule Polymerization Studies, Department of Medicinal Chemistry and Pharmacognosy, University of Mississippi04/1993
National and International Invited Seminars/Lectures, Structural Probes of Microtubule Dynamics, Department of Physiology, University of Mississippi Medical Center05/1992
National and International Invited Seminars/Lectures, Structural Probes of Microtubule Dynamics, Department of Physiology, University of Mississippi Medical Center10/1991
National and International Invited Seminars/Lectures, Structural Studies on the Role of Divalent Cations in Microtubule Dynamics, University of Illinois at Chicago, Chicago, IL10/1991
National and International Invited Seminars/Lectures, Error Propagation and Parameter Determination in Fitting Binding Data to the Exclusion Model, 4th Southeast DNA Symposium, October, 1990, University of Mississippi, Oxford, MS10/1990
National and International Invited Seminars/Lectures, Tubulin Microtubule Dynamics: The Role of Metals and Nucleotides, Yoknapatawpha Conference on Biomolecular Science, University of Mississippi, Oxford, MS11/1989
National and International Invited Seminars/Lectures, Mg+2 Dependence of Guanine Nucleotide Binding to Tubulin, Meeting On The Cytoskeleton, Oxford, England10/1988
National and International Invited Seminars/Lectures, The Role of Divalent Cations in Microtubule Assembly and Dynamics, Mississippi State University, Starkville, MS03/1988

Professional Membership and Service

Gibbs Conference on Biothermodynamics, Officer, Treasurer2010 - Present
Mississippi Biophysical Consortium, Meeting Organizer2008 - Present
Academic Appointment - University of Mississippi, Oxford, Joint Appointment2006
Beckman XLA/XLI Analytical Ultracentrifuges, Ad Hoc Member, NIH Shared Instrumentation Study Section for Beckman XLA/XLI Analytical Ultracentrifuges2002 - 2003
Gibbs Society of Biological Thermodynamics, Inc, President Elect, President Elect of the Gibbs Society of Biological Thermodynamics, Inc2001 - 2003
Beckman XLA Analytical Ultracentrifuges, Ad Hoc Member, NIH Shared Instrumentation Study Section for Beckman XLA Analytical Ultracentrifuges1993 - 1995
Gibbs Society of Biological Thermodynamics, Inc, Member, Gibbs Society of Biological Thermodynamics, Inc1991 - Present
Academic Appointment - Vanderbilt University, Research Insructor of Molecular Biology1985 - 1987
American Association for the Advancement of Science, Member
American Heart Association, Reviewer, Grant Proposal
American Society for Cell Biology, Member
Analytical Biochemistry, Reviewer, Journal Article
Association of Biochemistry Course Directors, Member
BBA, Reviewer, Journal Article
Biochemistry, Reviewer, Journal Article
Biophysical Journal, Reviewer, Journal Article
Biophysical Society, Member
Biopolymers, Reviewer, Journal Article
European J. Medicinal Chemistry, Reviewer, Journal Article
J. Biological Chemistry, Reviewer, Journal Article
J. Medicinal Chemistry, Reviewer, Journal Article
J. Mol. Biol., Reviewer, Journal Article
J. Molecular Biology, Reviewer, Journal Article
J. Neuroscience, Reviewer, Journal Article
J. Theor. Biol., Reviewer, Journal Article
Molecular Pharmaceutics, Reviewer, Journal Article
NASA, Reviewer, Grant Proposal
Nature Structural & Molecular Biology, Reviewer, Journal Article
Nature, Reviewer, Journal Article
NSF, Reviewer, Grant Proposal
25th Annual Gibbs Conference, Co-Organizer, 25th Annual Gibbs Conference on Biothermodynamics, September, Carbondale, Il2011
Biophysical Chemistry, Co-Editor, Special Issue in Honour of 25th Annual Gibbs Conference on Biothermodynamics, Biophysical Chemistry2011
Methods in Cell Biology, Co-Editor, Methods in Cell Biology, Vol 95, Microtubules, in vitro2010
Methods in Cell Biology, Co-Editor, Methods in Cell Biology, Vol 89, Biophysical Tools for Biologists, Volume 2, in vivo Techniques2009
NIH Shared Instrumentation Study Section, Ad Hoc Member, NIH Shared Instrumentation Study Section for Beckman XLA/XLI Analytical Ultracentrifuges, CD's and purification systems2009
Methods in Cell Biology, Co-Editor, Methods in Cell Biology, Vol 84, Biophysical Tools for Biologists, Volume 1, in vitro Techniques, pp. 1-9722008
Beckman XLA/XLI Analytical Ultracentrifuges, Ad Hoc Member, NIH Shared Instrumentation Study Section for Beckman XLA/XLI Analytical Ultracentrifuges2006
American Heart Association - National Center, Attendee, Meeting, BASIC 1 (Basic Cell & Molecular Biology 1) Study Group, Chicago, IL2005
NIH Panel, Ad Hoc Member, NIH Panel on Continued Development and Maintenance of Bioinformatics and Computational Biology Software2005
American Heart Association - National Center, Attendee, Meeting, BASIC 1 (Basic Cell & Molecular Biology 1) Study Group, Dallas, TX2005
Biophysical Chemistry, Co-Editor, Special Issue in Honour of David Yphantis, Vol 1082004
Biophysical Society Meeting, Workshop Organizer, Hetero-Association Methods: Quantifying Reversible Macromolecular Association, at Biophysical Society Meeting in San Antonio2003
Awards Committee, 2nd Beckman Symposium, Committee Member, Awards Committee, 1st Beckman Symposium1998
Biophysics Society, Workshop Organizer, Analytical Ultracentrifuge Applications Workshop at the 1997 Biophysics Society Meeting1997
Awards Committee, 1st Beckman Symposium, Committee Chair, 1st Beckman Symposium1997
11th Annual Gibbs Conference, Co-Organizer, 11th Annual Gibbs Conference on Biothermodynamics1997
BRSG Study Section, Ad Hoc Member, BRSG Study Section, Univ. of Mississippi1992

Committee Service

Peterson’s Guide Committee2001 - 2009
Graduate Student Recruitment Committee, Chair2001 - 2005
Biochemistry Search Committee for Faculty Positions2000 - 2002
Course Coordinators Manual Subcommittee, Chair1998 - 2001
Course Evaluation Subcommittee, Chair1998 - 2001
CC Evaluation Subcommittee, Member1997 - 2000
School Of Medicine - Curriculum, Member1997 - 2000
Biochemistry Committee on Graduate Curriculum, Chair1992 - 1999
Biochemistry Poster Committee, Member1989 - 2001
Biochemistry Graduate Student Guidelines Committee, Member1989 - 1997
Information Technology Subcommittee of the LCME Self Study
Research Subcommittee of the LCME Self Study
Faculty Senate Subcommittee on University Research Brochure, Chair

Other Service

Information Systems Strategic Planning Report - Basic Science Working Group12/2000 - 2001
Academic Appointment, Professor of Biochemistry07/1997 - Present
UMMC Analytical Ultracentrifuge Center, Director1995 - Present
Medical Biochemistry, 610, Course Coordinator1995 - 2007
Academic Appointment, Associate Professor of Biochemistry07/1992 - 06/1997
Faculty Senate1992 - 1995
Graduate Biochemistry, Course Coordinator1990 - 2008
Biochemistry Journal Club, Coordinator1988 - 1993
Academic Appointment, Assistant Professor of Biochemistry11/1987 - 06/1992

Teaching Experience

Course, Medical Biochemistry 610
Course, Physical Biochemistry
Course, Portal Biochemistry
Small Group, Proteomics, Structural Proteomics and Bioinformatics: NewWinter 2002
Small Group, Concepts in Linkage and CooperativityWinter 2000
Small Group, Molecular MotorsFall 1996
Lecture, Lecturer, Analytical Ultracentrifugation/XLA Workshop for Shared Instrumentation Grant 1995
Course, Proteins 1993
Small Group, CooperativitySpring 1993
Small Group, Microtubules and MitosisWinter 1991
Small Group, Macromolecular AssemblySpring 1989

Directed Student Learning

Doctoral Advisory Committee Member, Advised: Daniel Lyons
Doctoral Advisory Committee Member, Advised: Thomas Flanagan
Doctoral Advisory Committee Member, Advised: Andrew Gilder
Doctoral Advisory Committee Member, Advised: Payal Vayas
Doctoral Advisory Committee Chair, Advised: Holland Alday
Doctoral Advisory Committee Member, Advised: Eric George
Master's Thesis Committee Member, Advised: Valeria Cucchiarelli
Doctoral Advisory Committee Member, Advised: Asish Aggarwal
Doctoral Advisory Committee Member, Advised: Dan Yellajoshyula
Doctoral Advisory Committee Member, Advised: Xiaochun Shi
Doctoral Advisory Committee Member, Advised: Alka Prasad
Doctoral Advisory Committee Member, Advised: Jing Li
Doctoral Advisory Committee Member, Advised: Patrick Kyle
Doctoral Advisory Committee Member, Advised: Kiranan Chatti
Doctoral Advisory Committee Member, Advised: Nian Huang
Doctoral Advisory Committee Chair, Advised: Chris Sontag
Doctoral Advisory Committee Member, Advised: Moonkyu Kang
Doctoral Advisory Committee Member, Advised: Sid De
Master's Thesis Committee Member, Advised: Nancy Stubbs
Doctoral Advisory Committee Member, Advised: Kamini Hingorani
Doctoral Advisory Committee Member, Advised: Meylssa Bratton
Doctoral Advisory Committee Member, Advised: Akash Gunjan
Doctoral Advisory Committee Member, Advised: Zhenyu Zhu
Doctoral Advisory Committee Chair, Advised: Bojana Vulevic
Doctoral Advisory Committee Member, Advised: Fenfei Leng
Doctoral Advisory Committee Member, Advised: Reid Bishop
Master's Thesis Committee Member, Advised: Oca Cossio
Doctoral Advisory Committee Chair, Advised: Bettye Sue Hennington
Doctoral Advisory Committee Member, Advised: Stan Smith
Doctoral Advisory Committee Member, Advised: Harold Brooks
Doctoral Advisory Committee Member, Advised: T.K. Harris
Doctoral Advisory Committee Member, Advised: Dong Chul Suh
Doctoral Advisory Committee Member, Advised: Julio Herrera
Doctoral Advisory Committee Member, Advised: Tamba Dunbar