Gene L. Bidwell
Associate Vice Chancellor for Research
Department:
SER-Office-Vice Chancellor
Email:
gbidwell@umc.edu
Work Phone:
(601) 984-6787
Education
| University of Mississippi Medical Center, Postdoctoral Fellow, Biochemistry | 2007 |
| University of Mississippi Medical Center, PhD, Biochemistry | 2002 |
| University of Mississippi, BA, Biochemistry | 1998 |
Current Positions
| Associate Professor, School of Medicine, Department of Pharmacology / Toxicology | 07/2018 - Present |
| Associate Professor, School of Medicine, Department of Neurology | 07/2018 - Present |
| Associate Professor, School of Medicine, Department of Biochemistry | 07/2016 - Present |
| Member | 2013 - Present |
| Director | 2012 - Present |
| Graduate Faculty, School of Graduate School in the Health Sciences | 2012 - Present |
| Associate Member | 2010 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Academic Appointments or Other Previous Appointments
| Associate Professor, Department of Neurology, University of Mississippi Medical Center, School of Medicine, Department of Neurology | 07/2016 - 06/2018 |
| Assistant Professor, Department of Biochemistry, University of Mississippi Medical Center, School of Medicine, Department of Biochemistry | 2013 - 06/2016 |
| Assistant Professor, Department of Neurology, University of Mississippi Medical Center, School of Medicine, Department of Neurology | 10/2011 - 06/2016 |
| Instructor, Department of Biochemistry, University of Mississippi Medical Center, School of Medicine | 2010 - 2011 |
| Postdoctoral Fellow, Department of Biochemistry, University of Mississippi Medical Center, School of Medicine | 2007 - 2010 |
| Graduate Student, Department of Biochemistry, University of Mississippi Medical Center, School of Medicine | 2002 - 2007 |
| Undergraduate Research Assistant, Department of Chemistry and Biochemistry, University of Mississippi | 2000 - 2002 |
Sponsored Program Funding
| Extramural, An Anti-inflammatory Biologic for Ischemic Stroke, National Institute of Neurological Disorders and Stroke, NIH R21NS121450 (MPI with Eddie Perkins, Pending Review) | 04/2021 - 03/2023 |
| Extramural, Development of Peptide Inhibitors of NF-kB for Treatment of Ischemic Stroke, National Institute of Neurological Diseases and Stroke, NIH F31NS117031 (John Aaron Howell, PI, Pending Review) | 04/2021 - 03/2023 |
| Extramural, sGC Activators for Preeclampsia, National Heart Lung and Blood Institute, NIH R01 (Joey Granger, PI, Pending Review) | 01/2021 - 12/2025 |
| Extramural, Industry Sponsored Research and Licensing Agreement, Industry Partner (confidential, contract negotiations underway) | 09/2020 - 03/2021 |
| Extramural, Drug Delivery Proteins Research and Licensing Agreement, Industry Partner (confidential) | 07/2020 - 12/2020 |
| Extramural, Renal Targeted Vascular Growth Factor Therapy for Polycystic Kidney Disease, Great Ormond Street Hospital (David Long, PI, Pending Review) | 06/2020 - 11/2022 |
| Extramural, A Novel Protein Delivery System for Therapy of Preeclampsia, National Heart Lung and Blood Institute, NIH 2R01HL121527 | 04/2020 - 03/2024 |
| Extramural, The Use of a Biopolymer-fused Form of VEGF-B for Treatment of Preeclampsia, National Heart Lung and Blood Institute, NIH F31HL151180 (Jamarius Waller, PI) | 03/2020 - 02/2023 |
| Extramural, Hypertension in Adult IUGR Offspring: Beneficial Effects of Perinatal Intervention, National Heart Lung and Blood Institute, NIH R01HL143495 (Barbara Alexander, PI) | 11/2019 - 11/2022 |
| Extramural, A Maternally Sequestered sFlt-1 Targeted Biologic for Treatment of Preeclampsia, American Heart Association Translational Project Award (relinquished 3/31/20 to accept R01 funding) | 07/2019 - 06/2022 |
| Extramural, Hypertension in Adult IUGR Offspring: Beneficial Effects of Perinatal Intervention, National Heart Lung and Blood Institute, NIH R56HL143459 (Barbara Alexander, PI) | 09/2018 - 08/2019 |
| Extramural, Precision Medicine: Selective Renal Targeting to Counteract Inflammation in Chronic Kidney Disease via Kidney-specific Drug Delivery Technology, American Heart Association Innovative Project Award (Alejandro Chade, PI) | 07/2018 - 06/2020 |
| Extramural, Novel Therapeutic Interventions in Renovascular Disease, American Heart Association Transformational Project Award (Alejandro Chade, PI, award deferred to accept R01) | 07/2018 - 06/2021 |
| Extramural, Microcirculation in Renovascular Hypertension., National Heart Lung and Blood Institute, NIH R01HL095638 (Multi-PI with Alejandro Chade) | 07/2018 - 06/2022 |
| Extramural, Therapeutic Angiogenesis for Ischemic Renal Disease, National Institutes of Health Niche Assessment Program, NIH1612TN | 10/2017 - 09/2018 |
| Intramural, Microcirculation in Renovascular Hypertension., UMMC Intramural Research Support Program | 09/2017 - 08/2018 |
| Extramural, Elastin-like Polypeptide – VEGF Fusion Protein for Renal Therapeutic Angiogenesis., National Heart Lung and Blood Institute, NIH SMARTT RSA-000447 | 08/2017 - 08/2018 |
| Extramural, A Novel Therapeutic for Preeclampsia., National Heart Lung and Blood Institute, NIH R01HL137791 (Eric George, PI) | 07/2017 - 06/2022 |
| Extramural, A Preclinical Trial of Therapeutic Angiogenesis Plus Angioplasty and Stenting for Renal Vascular Disease., National Institute of Diabetes and Digestive and Kidney Diseases, NIH R41DK109737 | 04/2017 - 03/2018 |
| Extramural, A Maternally Sequestered Biopolymer Drug Delivery System for Therapy of Preeclampsia., American Heart Association Postdoctoral Fellowship (Omar Logue, PI) | 01/2017 - 12/2018 |
| Extramural, A Novel Therapeutic for Preeclampsia. (Relinquished 6/30/2017 to accept R01 funding), American Heart Association Grant in Aid (Eric George, PI) | 07/2016 - 06/2018 |
| Extramural, A Novel Protein Delivery System for Therapy of Preeclampsia, National Heart Lung and Blood Institute, NIH 1R01HL121527 | 01/2014 - 12/2019 |
| Extramural, Novel Therapeutic Interventions In Renovascular Disease, American Heart Association Established Investigator Award (Alejandro Chade, PI) | 01/2014 - 12/2018 |
| Extramural, A Novel Protein Delivery System for Therapy of Preeclampsia (Relinquished 1/15/2014 to accept R01 funding), American Heart Association Scientitst Development Grant | 07/2013 - 06/2017 |
| Intramural, Development of an anti-angiogenic sFlt miniprotein for treatment of corneal neovascularization, UMMC Intramural Research Support Program | 05/2013 - 04/2014 |
| Extramural, Thermally Targeted Delivery of Therapeutic Peptides, National Cancer Institute, NIH R43CA135799 (Drazen Raucher, PI) | 07/2009 - 06/2010 |
| Extramural, Thermally Targeted Delivery of a c-Myc Inhibitory Peptide In Vivo Using Elastin-like Polypeptide, Department of Defense (DoD) Breast Cancer Research Program (BCRP) Era of Hope Postdoctoral Award | 10/2008 - 09/2012 |
| Extramural, Thermally Targeted Delivery of Doxorubicin to Solid Tumors in vivo using Elastin-like Polypeptide, The Milheim Foundation for Cancer Research | 09/2007 - 08/2008 |
Publications
Patents | |
| Bidwell, G.L. III, and Perkins, E. ELP Delivered Therapeutics for Cerebrovascular and Neurological Disorders. US Provisional Patent filed March 31, 2020. | 2020 |
| Bidwell, G.L. III, and George, E.M. Molecular Size of Elastin-like Polypeptide Delivery System for Therapeutics Modulates Deposition in The Placenta. US Provisional Patent filed March 29, 2019. Converted to Continuation-in-part of US patent 10081667 March 30, 2020. | 2019 |
| Bidwell, G.L. III, and Chade, A.R. Molecular Size of Elastin-like Polypeptide Delivery System for Therapeutics Modulates Intrarenal Deposition and Bioavailability. US Provisional Patent filed March 29, 2019. US Full Utility Patent filed March 30, 2020. | 2019 |
| Bidwell, GL III and George, EM. Ocular Compositions and Methods Thereof. PCT Full Utility patent filed April 29, 2015. US Full Utility Patent Filed October 27, 2016. | 2015 |
| Chade, AR and Bidwell, GL III. Kidney-targeted Drug Delivery Systems. PCT Full Utility patent filed November 2015. US Full Utility Patent issued June 18, 2019. European National Phase application filed July 27, 2017. | 2015 |
| Bidwell, GL III, and George, EM. Composition And Method For Therapeutic Agent Delivery During Pregnancy. PCT Full Utility patent filed October 1, 2014. US Full Utility Patent issued September 25, 2018. Patent Number 10081667. European National Phase Application issued May 6, 2020. | 2014 |
| Raucher, D and Bidwell, GL III. Targeted Delivery of Therapeutic Peptides by Thermally Responsive Biopolymers. USPTO Full Utility patent issued September 2014. Patent Number 12/789,215. | 2014 |
| Raucher, D, Bidwell, GL III, Fokt I, and Priebe W. Thermally Targeted Delivery of Medicaments. USPTO Full Utility patent issued July 2012. Patent Number 12/162,283. | 2012 |
| Raucher, D. Bidwell, GL III, and Perkins, E. Cell Penetrating Peptide Fused Elastin-like Polypeptides for Delivery of Agents Across the Blood Brain Barrier. USPTO Full Utility patent filed April 2011. Patent Number 61/326,336. | 2011 |
| Raucher, D, Bidwell, GL III, and Kratz, F. Composition for targeted delivery of an active agent and method for use thereof. USPTO Full Utility patent filed December 2010. Patent Number 12/964,099. | 2010 |
| Raucher, D, Bidwell, GL III, and Massodi, I. Inhibition of Cancer Metastasis by Cell Penetrating Peptides Fused to Elastin-like Biopolymers. USPTO full utility patent filed May 2010. USPTO full utility patent issued June, 2017. Patent Number 12/789,236. | 2010 |
Policy Paper | |
| Ilekis J, Tsilou E, Fisher S, Abrahams V, Soares M, Cross J, Zamudio S, Illsley N, Myatt,L, Colvis C, Costantine M, Haas D, Sadovsky,Y, Weiner C, Rytting E, and Bidwell GL III. Placental Origins of Adverse Pregnancy Outcomes: Potential Molecular Targets- An Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. American Journal of Obstetrics and Gynecology. 215(1 Suppl):S1-S46, 2016. | 2016 |
Journal Article | |
| Gurumurthy, B., Tucci, M. A., Fan, L. W., Benghuzzi, H. A., Pal, P., Bidwell, G. L. III, Marocho, S. M. S., Cason, Z., Gordy, D., and Janorkar, A. V. Collagen-Elastin-Like Polypeptide-Bioglass Scaffolds for Guided Bone Regeneration. Advanced Healthcare Materials. 9(4):e1901385, 2020. | 2020 |
| Waller, J. P., Burke, S., Engel, J. E., Chade, A. R., and Bidwell, G. L. III. Dose-Escalating Toxicology of the Candidate Biologic ELP-VEGF. Journal of Controlled Release. In Revision, 2020. | 2020 |
| Engel, J. E., Williams, M. L., Williams, E., Azar, C., Taylor, E. B., Bidwell, G. L. III, and Chade, A. R. Recovery of Renal Function Following Kidney Specific VEGF Therapy in Experimental Renovascular Disease. American Journal of Nephrology. In Press, 2020. | 2020 |
| Eddy, A. C., Howell, J. A., Chapman, H., Taylor, E., Mahdi, F., George, E. M., and Bidwell, G. L. III. A Biopolymer-delivered, Maternally Sequestered NF-kB Inhibitory Peptide for Treatment of Preeclampsia. Hypertension. 75(1):193-201, 2020. | 2020 |
| Chade, A. R., Williams, M. L., Engel, J. E., Williams, E., and Bidwell, G. L. III. Molecular Targeting of Renal Inflammation using Drug Delivery Technology to Inhibit NF-kB Improves Renal Recovery in Chronic Kidney Disease. American Journal of Physiology – Renal Physiology. 319(1):F139-F148, 2020. | 2020 |
| Guise, E., Engel, J. E., Williams, M. L., Mahdi, F., Bidwell, G. L. III, and Chade, A. R. Biopolymer-delivered Vascular Endothelial Growth Factor Improves Renal Outcomes Following Revascularization. American Journal of Physiology – Renal Physiology. 316(5):F1016-F1025, 2019. | 2019 |
| Engel, J. E., Williams, E., Williams, M. L., Bidwell, G. L. III, and Chade, A. R. Targeted VEGF therapy induces long-term renal recovery in chronic kidney disease via macrophage polarization. Hypertension. 74(5):1113-1123, 2019. | 2019 |
| Mahdi, F., Chade, A. R., and Bidwell, G. L. III. Utilizing a Kidney-Targeting Peptide to Improve Renal Deposition of a Pro-Angiogenic Protein Biopolymer. Pharmaceutics, 11(10). pii: E542, 2019. | 2019 |
| Giambrone, A. B., Logue, O. C., Shao, Q., Bidwell, G. L. III, and Warrington, J. P. Perinatal Microbleeds and Neuroinflammation in E19 Rat Fetuses Exposed to Placental Ischemia. International Journal of Molecular Sciences. 20(16), pii: E4051, 2019. | 2019 |
| Kuna, M., Waller, J. P., Logue, O. C., and Bidwell, G. L. III. Polymer Size Affects Biodistribution and Placental Accumulation of the Drug Delivery Biopolymer Elastin-Like Polypeptide in a Rodent Pregnancy Model. Placenta. 72–73 (2018) 20–27, 2018. | 2018 |
| Kuna, M., Mahdi, F., Chade, A. R., and Bidwell, G. L. III. Molecular Size Modulates Pharmacokinetics, Biodistribution, and Renal Deposition of the Drug Delivery Biopolymer Elastin-like Polypeptide. Scientific Reports. May 21;8(1):7923, 2018. | 2018 |
| Zhang Y., Zai-Rose V., Price C.J., Ezzell N.A., Bidwell, G. L. III, Correia J.J., and Fitzkee N.C. Modeling Early Stages of Phase Separation in Disordered Elastin-Like Proteins. Biophysical Journal. 114(7):1563-1578, 2018. | 2018 |
| Bidwell G. III, Mahdi F, Shao Q, Logue OC, Waller JP, Reese C, and Chade AR. A Kidney-selective Biopolymer for Targeted Drug Delivery. American Journal of Physiology - Renal Physiology. 312(1):F54-F64, 2017. | 2017 |
| Logue OC, Mahdi F, Chapman H, George EM, and Bidwell G. III. A Maternally Sequestered, Biopolymer-stabilized VEGF Chimera for Treatment of Preeclampsia. Journal of the American Heart Association. 6(12), 6:e007216, 2017 | 2017 |
| Chade, AR, Williams ML, Guise E, Vincent LJ, Harvey TW, Kuna M, Mahdi F, and Bidwell GL III. Biopolymer-delivered VEGF for Therapeutic Angiogenesis in Experimental Renovascular Disease: Targeting the Kidney via Systemic Administration. Kidney International. Dec 19. pii: S0085-2538(17)30787-1, 2017. | 2017 |
| Chade AR, Tullos NA, Harvey TW, Mahdi F, and Bidwell GL 3rd. Renal Therapeutic Angiogenesis using Bioengineered Polymer-Stabilized VEGF Constructs. Journal of the American Society of Nephrology, 27(6):1741-52, 2016. | 2016 |
| George EM, Mahdi F, Logue OC, Robinson G, and Bidwell GL III. Corneal Penetrating Elastin-like Polypeptide Carriers. Journal of Ocular Pharmacology and Therapeutics. 32:3, 2016. | 2016 |
| McGowan JWD, Shao Q, Vig PJS, and Bidwell GL III. Intranasal Administration of Elastin-like Polypeptide for Therapeutic Delivery to the Central Nervous System. Drug Design, Development, and Therapy. 2016(10): 2803-13, 2016. | 2016 |
| McGowan JWD and Bidwell GL III. The Use of Ex Vivo Whole Organ Imaging and Quantitative Tissue Histology to Determine the Biodistribution of Fluorescently Labeled Molecules. J Vis Exp. Dec 24;(118), 2016. | 2016 |
| Bae J, McNamara LE, Nael MA, Mahdi F, Doerksen RJ, Bidwell GL 3rd, Hammer NI, Jo S. Nitroreductase-triggered activation of a novel caged fluorescent probe obtained from methylene blue. Chem Commun (Camb). 2015 Aug 18;51(64). | 2015 |
| George, E. M., Liu, H., Robinson, G., Mahdi, F., Perkins, E.,P., and Bidwell, G. L. III. Growth Factor Purification and Delivery Systems (PADS) for Therapeutic Angiogenesis. Vascular Cell, 7:1, 2015. | 2015 |
| George EM, Liu H, Robinson GG, Bidwell GL 3rd. A polypeptide drug carrier for maternal delivery and prevention of fetal exposure. J Drug Target. 2014 Dec;22(10):935-47. | 2014 |
| Lyons DF, Le V, Kramer WH, Bidwell GL 3rd, Lewis EA, Raucher D, Correia JJ. Effect of basic cell-penetrating peptides on the structural, thermodynamic, and hydrodynamic properties of a novel drug delivery vector, ELP[V5G3A2-150]. Biochemistry. 2014 Feb 18;53(6):1081-91. | 2014 |
| Lyons DF, Le V, Bidwell GL 3rd, Kramer WH, Lewis EA, Raucher D, Correia JJ. Structural and hydrodynamic analysis of a novel drug delivery vector: ELP[V5G3A2-150]. Biophys J. 2013 May 7;104(9):2009-21. | 2013 |
| Bidwell, G. L. III, Perkins, E., Hughes, J. D., Khan, M., James, J. R., and Raucher, D. Thermally Targeted Delivery of a c-Myc Inhibitory Polypeptide Inhibits Tumor Progression and Extends Survival in a Rat Glioma Model. PLoS One, 8(1), 2013. | 2013 |
| Bidwell GL 3rd, Perkins E, Raucher D. A thermally targeted c-Myc inhibitory polypeptide inhibits breast tumor growth. Cancer Lett. 2012 Jun 28;319(2):136-43. | 2012 |
| Bidwell GL 3rd, Whittom AA, Thomas E, Lyons D, Hebert MD, Raucher D. A thermally targeted peptide inhibitor of symmetrical dimethylation inhibits cancer-cell proliferation. Peptides. 2010 May;31(5):834-41. | 2010 |
| Massodi I, Moktan S, Rawat A, Bidwell GL 3rd, Raucher D. Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. Int J Cancer. 2010 Jan 15;126(2):533-44. | 2010 |
| Bidwell GL 3rd, Davis AN, Raucher D. Targeting a c-Myc inhibitory polypeptide to specific intracellular compartments using cell penetrating peptides. J Control Release. 2009 Apr 2;135(1):2-10. | 2009 |
| Massodi I, Bidwell GL 3rd, Davis A, Tausend A, Credit K, Flessner M, and Raucher D Inhibition of ovarian cancer cell metastasis by a fusion polypeptide Tat-ELP Clin Exp Metastasis. 2009;26(3):251-60 | 2009 |
| Bidwell GL 3rd, Davis AN, Fokt I, Priebe W, Raucher D. A thermally targeted elastin-like polypeptide-doxorubicin conjugate overcomes drug resistance. Invest New Drugs. 2007 Aug;25(4):313-26. | 2007 |
| Bidwell GL 3rd, Fokt I, Priebe W, Raucher D. Development of elastin-like polypeptide for thermally targeted delivery of doxorubicin. Biochem Pharmacol. 2007 Mar 1;73(5):620-31. | 2007 |
| Bidwell GL 3rd, Raucher D. Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc. Biochem Pharmacol. 2006 Jan 12;71(3):248-56. | 2006 |
| Massodi I, Bidwell GL 3rd, Raucher D. Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery. J Control Release. 2005 Nov 28;108(2-3):396-408. | 2005 |
| Jia H, Satumba WJ, Bidwell GL 3rd, Mossing MC. Slow assembly and disassembly of lambda Cro repressor dimers. J Mol Biol. 2005 Jul 29;350(5):919-29. | 2005 |
| Bidwell GL 3rd, Raucher D. Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy. Mol Cancer Ther. 2005 Jul;4(7):1076-85. | 2005 |
Review Article | |
| Howell, J. A. and Bidwell, G. L. III. Targeting the Nuclear Factor kappa B Pathway for Therapy of Ischemic Stroke. Therapeutic Delivery. 11(2):113-123, 2020. | 2020 |
| Eddy, A. C., Bidwell, G. L. III, and George, E. M. Pro-angiogenic Therapeutics for Preeclampsia. Biology of Sex Differences. Aug 25;9(1):36, 2018. | 2018 |
| Logue OC, George EM, and Bidwell GL III. Preeclampsia and the Brain: Neural Control of Cardiovascular Changes During Pregnancy and Neurological Outcomes of Preeclampsia. Clinical Science. 130(16):1417-34, 2016. | 2016 |
| Logue OC, McGowan JWD, George EM, and Bidwell GL III. Therapeutic Angiogenesis by VEGF Supplementation for Treatment of Renal Disease. Current Opinion in Nephrology and Hypertension. 25(5):404-9, 2016. | 2016 |
| McGowan JW, Bidwell GL 3rd, Vig PJ. Challenges and new strategies for therapeutic peptide delivery to the CNS. Ther Deliv. 2015 Jul;6(7):841-53. | 2015 |
| Bidwell, G. L. III and George, E. M. Maternally Sequestered Therapeutic Polypeptides - A New Approach for the Management of Preeclampsia. Frontiers in Pharmacology, 5;5:201, 2014. | 2014 |
| Bidwell GL 3rd. Peptides for cancer therapy: a drug-development opportunity and a drug-delivery challenge. Ther Deliv. 2012 May;3(5):609-21. | 2012 |
| Bidwell GL 3rd, Raucher D. Cell penetrating elastin-like polypeptides for therapeutic peptide delivery. Adv Drug Deliv Rev. 2010 Dec 30;62(15):1486-96. | 2010 |
| Raucher D, Moktan S, Massodi I, Bidwell GL 3rd. Therapeutic peptides for cancer therapy. Part II - cell cycle inhibitory peptides and apoptosis-inducing peptides. Expert Opin Drug Deliv. 2009 Oct;6(10):1049-64. | 2009 |
| Bidwell GL 3rd, Raucher D. Therapeutic peptides for cancer therapy. Part I - peptide inhibitors of signal transduction cascades. Expert Opin Drug Deliv. 2009 Oct;6(10):1033-47. | 2009 |
| Raucher D, Massodi I, Bidwell GL. Thermally targeted delivery of chemotherapeutics and anti-cancer peptides by elastin-like polypeptide. Expert Opin Drug Deliv. 2008 Mar;5(3):353-69. | 2008 |
Editorial Commentary | |
| George EM, Bidwell GL 3rd. STOX1: a new player in preeclampsia? Hypertension. 2013 Mar;61(3):561-3. | 2013 |
Presentations
| Poster Presentation, Maeda, K. J., Hoskins, G. A., Bidwell, G. L., III, Garrett, M. R., and Sasser, J. M. Blood Brain Barrier Permeability and Brain Capillary Endothelial Cell Tight Junctions in the Dahl S Model of Spontaneous Superimposed Preeclampsia., Experimental Biology Annual Meeting (not presented due to coronavirus pandemic), San Diego, CA | 2020 |
| State/Local Invited Seminars/Lectures, Therapeutic Angiogenesis Using a New Class of Elastin-based Biologics, University of Mississippi Department of Biomolecular Sciences seminar, Oxford, MS | 2020 |
| Poster Presentation, Chade, A. R. and Bidwell, G. L., III. Chronic Kidney Disease, Inflammation, And Heart Failure with Preserved Ejection Fraction: A Renal-cardio Axis?, European Renal Association/ European Dialysis and Transplant Association 57th Congress (presented virtually), Milan, Italy | 2020 |
| Poster Presentation, Bidwell, G. L., III, Waller, J. P., Engel, J. E., and Chade, A. R. Dose Escalating Toxicology Study of ELP-VEGF, a Novel Biologic for Renal Therapeutic Angiogenesis., European Renal Association/ European Dialysis and Transplant Association 57th Congress (not presented due to coronavirus pandemic), Milan, Italy | 2020 |
| Poster Presentation, Akinleye, A., Burke, S., and Bidwell, G. L., III. Proximal Tubule Epithelial Cell Reabsorption of the Drug Delivery Protein Elastin-like Polypeptide., Experimental Biology Annual Meeting (not presented due to coronavirus pandemic), San Diego, CA | 2020 |
| Poster Presentation, Waller, J. P., Burke, S., Engel, J. E., Chade, A. R., and Bidwell, G. L., III. Determining the Effects of Pro-angiogenic ELP-VEGF-A Therapy on Tumor Growth and Progression., Experimental Biology Annual Meeting (not presented due to coronavirus pandemic), San Diego, CA | 2020 |
| State/Local Invited Seminars/Lectures, Chair, Biotechnology Session, Second Annual Mississippi IDeA Conference, Jackson, MS | 2019 |
| Regional Invited Seminars/Lectures, Developing New Therapeutics using the Elastin-like Polypeptide Drug Delivery System, Southeastern Regional Biophysical Consortium, Baton Rouge, LA | 2019 |
| State/Local Invited Seminars/Lectures, Developmental Therapeutics for Renal Disease, UMMC Pharmacology departmental seminar, Jackson, MS | 2019 |
| State/Local Invited Seminars/Lectures, Elastin-like Polypeptide Fusion Proteins: A New Class of Biological Therapeutics, Advanced Topics in Biomedical Research Seminar Series, G.V. Sonny Montgomery Veterans Affairs Medical Center, Jackson, MS | 2019 |
| Poster Presentation, Gurumurthy, B., Tucci, M. A., Fan, L. W., Benghuzzi, H. A., Pal, P., Bidwell, G. L., III, Salazar Marocho, S. M., Cason, Z., and Janorkar, A. V. In vivo Evaluation of Biocompatibility, Degradability, and Bone Regenerative Potential of Collagen-Elastin-like Polypeptide Bioglass Composite Scaffolds., Society for Biomaterials Annual Meeting, Seattle, WA | 2019 |
| Poster Presentation, Logue, O. C., Eddy, A. C., Moore, K., Chapman, H., George, E. M., and Gene L. Bidwell, III. The ELP-VEGF Fusion Protein is Bioavailable after Subcutaneous Administration and Prevents Increased Blood Pressure in Response to Placental Ischemia., American Heart Association Council on Hypertension, New Orleans, LA | 2019 |
| Poster Presentation, Chade, A. R., Engel, J. E., Williams, E., and Bidwell, G. L., III. A Novel Kidney-targeted Bioengineered Carrier for VEGF Delivery in Experimental Renovascular Disease: Proof of Concept., European Renal Association/ European Dialysis and Transplant Association 56th Congress, Budapest, Hungary | 2019 |
| Poster Presentation, Chade, A. R., Engel, J. E., Williams, E., and Bidwell, G. L., III. Molecular Targeting of Renal Inflammation Using Drug Delivery Technology in Chronic Kidney Disease., European Renal Association/ European Dialysis and Transplant Association 56th Congress, Budapest, Hungary | 2019 |
| Poster Presentation, Waller, J. P., Burke, S., Logue, O. C., and Bidwell, G. L., III. A Biopolymer-fused Form of VEGF-B for Treatment of Preeclampsia., Experimental Biology Annual Meeting, Orlando, FL | 2019 |
| Poster Presentation, Howell, J. A., Perkins, E., and Bidwell, G. L., III. Development of Peptide Inhibitors of Nuclear Factor kappa B as Therapeutics for Ischemic Stroke., Experimental Biology Annual Meeting, Orlando, FL | 2019 |
| Poster Presentation, Guise, E., Engel, J. E., Williams, M. L., Bidwell, G. L., III, and Chade, A. R., Bioengineered VEGF Therapy Following Angioplasty in Renovascular Disease: More and Better Microvessels., Experimental Biology Annual Meeting, Orlando, FL | 2019 |
| Poster Presentation, Engel, J. E., Guise, E., Bidwell, G. L., III, and Chade, A. R. VEGF Therapy Shifts Macrophage Phenotype and Improves Renal Recovery in Chronic Kidney Disease., Experimental Biology Annual Meeting, Orlando, FL | 2019 |
| Poster Presentation, Giambrone, A. B., Logue, O. C., Shao, Q., Bidwell, G. L., III, and Warrington, J. P. Placental Ischemia Exposure Leads to Increased Cerebral Microbleeds in Embryonic Day 19 Rat Offspring., International Stroke Conference, Honolulu, HI | 2019 |
| State/Local Invited Seminars/Lectures, Performing Drug Development Research at an Academic Medical Center, Millsaps College Senior Seminar, Jackson, MS | 2018 |
| State/Local Invited Seminars/Lectures, Developing New Therapies for Renal Disease, UMMC Pathology Research Day, Jackson, MS | 2018 |
| Poster Presentation, Chade, A. R., Engel, J. E., Williams, M., and Bidwell, G. L., III. Therapeutic Angiogenesis Promotes Renal Recovery in CKD Partly by Shifting Macrophage Phenotype., European Renal Association/ European Dialysis and Transplant Association 55th Congress, Copenhagen, Denmark | 2018 |
| Poster Presentation, Bidwell, G. L., III, Kuna, M., Logue, O. C., Eddy, A., Chapman, H., and George, E. M. Maternally Sequestered Biologics for Treatment of Preeclampsia., International Society for the Study of Hypertension in Pregnancy, Amsterdam, Netherlands | 2018 |
| Poster Presentation, Eddy, A., Chapman, H., George, E. M, and Bidwell, G. L., III. A Novel NF-κB Inhibitory Peptide-Based Therapeutic for the Management of Preeclampsia., International Society for the Study of Hypertension in Pregnancy, Amsterdam, Netherlands | 2018 |
| Poster Presentation, Eddy, A., Mahdi, F., Chapman, H., Bidwell, G. L., III, and George, E. M. A Novel Peptide-Based Antagonist of sFlt-1., International Society for the Study of Hypertension in Pregnancy, Amsterdam, Netherlands | 2018 |
| Poster Presentation, Logue, O. C., Burke, S. P., George, E. M., and Bidwell, G. L., III. Daily Subcutaneous Administration of a Biopolymer-Stabilized VEGF Chimera Optimizes Therapeutic Efficacy in Treating a Rodent Model of Placental Ischemia., American Heart Association Council on Hypertension, Chicago, IL | 2018 |
| Poster Presentation, Warrington, J. P., Logue, O. C., Bidwell, G. L., III, and Shao, Q. Placental Ischemia Exposure leads to a Pro-Inflammatory Environment in Brains of Embryonic Day 19 Rat Offspring., American Heart Association Council on Hypertension, Chicago, IL | 2018 |
| Poster Presentation, Kuna, M., Waller, J. P., Logue, O. C., and Bidwell, G. L., III. Polymer Size Affects Biodistribution and Placental Accumulation of Elastin-like Polypeptide in a Rodent Pregnancy Model., Experimental Biology Annual Meeting, San Diego, CA | 2018 |
| Poster Presentation, Logue, O. C., Mahdi, F., George, E. M., and Bidwell, G. L., III, Alternative Administration Routes of a Biopolymer-Stabilized VEGF Chimera to Optimize Therapeutic Efficacy in Treating a Rodent Model of Placental Ischemia., Experimental Biology Annual Meeting, San Diego, CA | 2018 |
| Poster Presentation, Eddy, A. C., Chapman, H., Mahdi, F., George, E. M., and Bidwell, G. L., III, A Novel Anti-Inflammatory Agent for the Management of Preeclampsia., Experimental Biology Annual Meeting, San Diego, CA | 2018 |
| Poster Presentation, Ross, C. A., Maeda, K. J., Logue, O. C., Bidwell, G. L., III, Garrett, M. R., Sasser, J. M. ELP-VEGF Treatment Improves the Maternal Syndrome of Preeclampsia in the Dahl Salt Sensitive Rat., Experimental Biology Annual Meeting, San Diego, CA | 2018 |
| Regional Invited Seminars/Lectures, Therapeutic Growth Factor Delivery using the Elastin-like Polypeptide Biopolymer Platform., 33rd Southern Biomedical Engineering Conference, Gulfport, MS | 2017 |
| State/Local Invited Seminars/Lectures, Targeting sFlt-1 for the Treatment of Preeclampsia., UMMC Physiology departmental seminar, Jackson, MS | 2017 |
| State/Local Invited Seminars/Lectures, Elastin-like Polypeptide Fusion Proteins, a Novel Class of Biologics., UMMC Pharmacology departmental seminar, Jackson, MS | 2017 |
| Poster Presentation, Chade, A. R., Guise, E., Williams, M., Harvey, T., and Bidwell, G. L., III. Reversal of Renal Dysfunction And Injury By Therapeutic Angiogenesis In Chronic Renal Disease: Not Everything Is Lost., European Renal Association/ European Dialysis and Transplant Association 54th Congress, Madrid, Spain | 2017 |
| Poster Presentation, Logue, O. C., Mahdi, F., George, E. M., and Bidwell, G. L. III. A Biopolymer-Stabilized VEGF Chimera is Maternally Sequestered and Prevents Placental Ischemia Induced Increases in Blood Pressure in the Reduced Uterine Perfusion Pressure Model of Preeclampsia., Experimental Biology Annual Meeting, Chicago, IL | 2017 |
| Poster Presentation, Kuna, M., Mahdi, F., McGowan J. W. D., and Bidwell, G. L. III. Impact of Molecular Weight on Pharmacokinetics, Biodistribution, and Renal Deposition of the Drug Delivery Biopolymer Elastin-Like Polypeptide., Experimental Biology Annual Meeting, Chicago, IL | 2017 |
| Poster Presentation, Kuna, M., Mahdi, F., McGowan J. W. D., and Bidwell, G. L. III. Pharmacokinetics and Intra-renal Accumulation of the Drug Delivery Biopolymer Elastin-like Polypeptide is Dependent on its Molecular Weight., American Society of Nephrology Annual Meeting, New Orleans, LA | 2017 |
| Poster Presentation, Chade, A. R., Williams, M., and Bidwell, G. L., III. Therapeutic Angiogenesis in Chronic Renal Disease: Underlying Mechanisms of a Potential Novel Strategy., American Society of Nephrology Annual Meeting, New Orleans, LA | 2017 |
| Regional Invited Seminars/Lectures, Developing the Elastin-like Polypeptide Biopolymer for Delivery of Growth Factor Therapeutics, Mississippi Regional Biophysical Consortium, Starkville, MS | 2016 |
| State/Local Invited Seminars/Lectures, Elastin-like Polypeptide as a Carrier for Ocular Drug Delivery, Research in Ophthalmology and Vision Sciences Seminar Series, UMMC Department of Ophthalmology, Jackson, MS | 2016 |
| Poster Presentation, Zamarripa, A. C., Lawson, W., Grill, R. J., Bidwell, G. L. III, and Grayson, B. E. Altered blood-barriers following rodent vertical sleeve gastrectomy., UM/UMMC Research Day, Jackson, MS | 2016 |
| Poster Presentation, Logue, O. C., Mahdi, F., George, E. M., and Bidwell, G. L. III. A Biopolymer-stabilized VEGF Chimera Reverses Angiogenic Imbalance In The Reduced Uterine Perfusion Pressure Model Of Preeclampsia., Experimental Biology Annual Meeting, San Diego, CA | 2016 |
| Poster Presentation, Chade, A. R., Vincent, L. J., Mahdi, F., Shao, Q., and Bidwell, G. L., III. A Novel Kidney-targeted Bioengineered Protein Carrier for Drug Delivery Binds to the Kidney Independent of the Species, Experimental Biology Annual Meeting, San Diego, CA | 2016 |
| Poster Presentation, McGowan J. W. D., Vig P. J. S., and Bidwell, G. L., III. The Use of Intransally-delivered Elastin-like Polypeptide for Drug Delivery to the Central Nervous System, Experimental Biology Annual Meeting, San Diego, CA | 2016 |
| Poster Presentation, Chade, A. R., Vincent, L. J., and Bidwell, G. L., III. A Novel Biopolymer-delivered VEGF for Therapeutic Angiogenesis in Renovascular Disease: Targeting the Kidney via Systemic Administration, European Renal Association/ European Dialysis and Transplant Association 53rd Congress, Vienna, Austria | 2016 |
| Poster Presentation, Lawson, W., Spann, R., Bidwell, G. L. III, Garrett, M. R., and Grayson, B. E. Altered barrier permeability and placental expression of MMP9, ILR1N and occludin in rat placenta following VSG, The Obesity Society Annual Meeting, New Orleans, LA | 2016 |
| Poster Presentation, Chade, A. R., Guise, E., Vincent, L. J., and Bidwell, G. L., III. PTRA Combined with Intra-renal Administration Of A Biopolymer-delivered VEGF Construct To Improve Renal Recovery: A New Therapeutic Strategy, American Society of Nephrology Annual Meeting, Chicago, IL | 2016 |
| Poster Presentation, Stewart, W., Chapman, H., Mahdi, F., Bidwell, G. L., III, and George, E. M. Characterization of a Novel Maternally Restricted Pro-angiogenic Therapeutic for Preeclampsia, American Heart Association Council on Hypertension, Orlando, FL | 2016 |
| National and International Invited Seminars/Lectures, Maternally Sequestered Delivery Systems for Prevention of Fetal Drug Exposure, NIH/NICHD Placental Origins of Adverse Pregnancy Outcomes: Potential Molecular Targets Workshop, Bethesda, MD | 2015 |
| State/Local Invited Seminars/Lectures, Maternally sequestered proteins for the treatment of preeclampsia, UMMC Pharmacology departmental seminar, Jackson, MS | 2015 |
| Platform Presentations, Logue, O. C., Mahdi, F., George, E. M., and Bidwell, G. L. III. A Biopolymer-Stabilized VEGF Chimera Reverses Angiogenic Imbalance In Vitro in the Reduced Uterine Perfusion Pressure Model of Preeclampsia, American Heart Association Council for Hypertension, Washington, DC | 2015 |
| Poster Presentation, Bidwell, G. L., III, Reese, C., Shao, Q., and Chade, A. R. A Kidney-targeted Protein Biopolymer Drug Delivery System, Experimental Biology Annual Meeting, Boston, MA | 2015 |
| Poster Presentation, McGowan J. W. D., Vig P. J. S., and Bidwell, G. L. III. Cell Penetrating Peptide Biopolymers for Drug Delivery to the Central Nervous System, Experimental Biology Annual Meeting, Boston, MA | 2015 |
| Poster Presentation, Zhang, Y., Bidwell, G. L. III, Correia, J. J., and Fitzkee, N. C. Simulating the Early Stages of ELP Aggregation Using a Biased Structural Model, Gibbs Conference on Biothermodynamics, Carbondale, IL | 2015 |
| Platform Presentations, Chade A. R. and Bidwell, G. L., III. Therapeutic Angiogenesis in Renal Artery Stenosis: Intra-renal Therapy Using a Biopolymer-delivered VEGF Ameliorates Microvascular Dysfunction and Damage, European Renal Association/ European Dialysis and Transplant Association 52nd Congress, London, UK | 2015 |
| Poster Presentation, Chade A. R., Harvey T. W., and Bidwell, G. L. III. Systemic Administration of a Biopolymer-delivered VEGF Improved Renal Hemodynamics and Microvascular Rarefaction in Renal Artery Stenosis, Experimental Biology Annual Meeting, Boston, MA | 2015 |
| Poster Presentation, Perez, A., Rey-Dios, R., Khan, M., Bidwell, G. L. III, and Perkins, E. Comparative Volumetric Assessment of a Murine Xenograft Malignant Glioma Model via Gadolinium Enhancement Pattern and Extent of Tissue Fluorescence (5-ALA, Fluorescein Sodium), Congress of Neurological Surgeons Annual Meeting, New Orleans, LA | 2015 |
| Poster Presentation, Zhang, Y., Bidwell, G. L. III, Correia, J. J., Fitzkee, N. C. Studying ELP Aggregation Using Computational Methods and NMR, Mississippi Academy of Sciences Annual Meeting, Hattiesburg, MS | 2015 |
| State/Local Invited Seminars/Lectures, Process of Intellectual Property Protection and Technology Transfer, UMMC Career Opportunity and Professional Development Lecture Series, Jackson, MS | 2015 |
| Poster Presentation, Lawson, W., Zamarripa, A. C., Spann, R., Enns, B., Bidwell, G. L. III, and Grayson, B. E. Maternal vertical sleeve gastrectomy results in reduced maternal-fetal barrier during gestation, Mississippi Academy of Sciences Annual Meeting, Hattiesburg, MS | 2015 |
| State/Local Invited Seminars/Lectures, The Elastin-like Polypeptide Drug Delivery System: Cancer Therapy, Preeclampsia, and Beyond, UMMC Neurobiology and Anatomical Sciences departmental seminar, Jackson, MS | 2014 |
| State/Local Invited Seminars/Lectures, Therapeutic Applications of the Elastin-like Polypeptide Drug Delivery System, University of Mississippi School of Pharmacy American Association of Pharmaceutical Sciences lecture, Oxford, MS | 2014 |
| Poster Presentation, Bidwell, G. L. III and George, E.M. Maternally Sequestered Polypeptide-based Therapeutics to Treat Preeclampsia, International Society for the Study of Hypertension in Pregnancy World Congress, New Orleans, LA | 2014 |
| Poster Presentation, Chade, A. R., Tullos, N. A., and Bidwell, G. L. III. Administration of elastin-like polypeptide-VEGF in the stenotic kidney: a novel targeted treatment to recover renal function, American Society of Nephrology Annual Meeting, Philadelphia, PA | 2014 |
| Poster Presentation, Bidwell, G. L. III, Liu, H., Robinson, G., Marquart, M., and George, E.M. A corneal penetrating drug delivery system based on elastin-like polypeptide, Experimental Biology Annual Meeting, San Diego, CA | 2014 |
| State/Local Invited Seminars/Lectures, The Elastin-like Polypeptide Drug Delivery System, Jackson State University Interdisciplinary Center of Nanotoxicity Seminar Series, Jackson, MS | 2013 |
| State/Local Invited Seminars/Lectures, The Elastin-like Polypeptide Drug Delivery System, Belhaven University Senior Toxicology Seminar Series, Jackson, MS | 2013 |
| State/Local Invited Seminars/Lectures, Maternally Restricted Therapeutic Proteins for Treatment of Preeclampsia, UMMC Biochemistry departmental seminar, Jackson, MS | 2013 |
| National and International Invited Seminars/Lectures, Delivery of an Anti-inflammatory NF-κB Inhibitory Polypeptide to Treat Preeclampsia, American Heart Association Council for High Blood Pressure Research Scientific Sessions, New Orleans, LA | 2013 |
| Poster Presentation, George, E. M., Liu, H., and Bidwell, G. L. III. Development of a Stabilized Bioactive VEGF Chimera for the Management of Preeclampsia, American Heart Association Council for High Blood Pressure Research Scientific Sessions, New Orleans, LA | 2013 |
| Poster Presentation, Bidwell, G. L. III, Liu, H., and George, E. M. A delivery system for protein and peptide-based therapeutics to treat preeclampsia, Experimental Biology Annual Meeting, Boston, MA | 2013 |
| State/Local Invited Seminars/Lectures, The Elastin-like Polypeptide Drug Delivery System, University of Mississippi Medical Center’s Center of Excellence in Cardiovascular-Renal Research Innovative Methods Seminar, Jackson, MS | 2012 |
| Poster Presentation, Bidwell, G. L. III, Perkins, E., Hughes, J., Khan, M, James, J., and Raucher, D. Treatment of Malignant Gliomas Using Thermally Targeted Peptide Therapeutics, American Academy for Neurology Annual Meeting, New Orleans, LA | 2012 |
| Poster Presentation, Bidwell, G. L. III, Perkins, E., and Raucher, D. Thermally Targeted Delivery of a c-Myc Inhibitory Peptide to Breast Tumors in vivo using Elastin-like Polypeptide, Department of Defense Breast Cancer Research Program (BCRP) Era of Hope Meeting, Washington, DC | 2011 |
| Poster Presentation, Bidwell, G. L. III, Perkins, E., and Raucher, D. Thermally Targeted Delivery of a c-Myc Inhibitory Peptide using Elastin-like Polypeptide: Project Year 3 Advancements, Department of Defense Breast Cancer Research Program (BCRP) Leading Innovative Networking and Knowledge Sharing (LINKS) Conference, Washington, DC | 2011 |
| Poster Presentation, Bidwell, G. L. III, Perkins, E., and Raucher, D. Thermally Targeted Delivery of a c-Myc Inhibitory Peptide to Breast Tumors in vivo using Elastin-like Polypeptide, American Association for Cancer Research Annual Meeting, Orlando, FL | 2011 |
| State/Local Invited Seminars/Lectures, Thermally Targeted Delivery of Therapeutic Peptides Using Elastin-like Polypeptide, 3rd Annual Mississippi Biophysical Constortium, Jackson, MS | 2010 |
| Poster Presentation, Bidwell, G. L. III, Benghuzzi, H., and Raucher, D. Thermally Targeted Delivery of a c-Myc Inhibitory Peptide using Elastin-like Polypeptide: Project Year 2 Advancements, Department of Defense Breast Cancer Research Program (BCRP) Leading Innovative Networking and Knowledge Sharing (LINKS) Conference, Washington, DC | 2010 |
| Poster Presentation, Bidwell, G. L. III, Hughes, J., Perkins, E., Raucher, D. A cell penetrating c-Myc inhibitory polypeptide accumulates in brain tumors in rats and inhibits tumor growth, American Association for Cancer Research Annual Meeting, Washington, DC | 2010 |
| State/Local Invited Seminars/Lectures, Thermally Targeted Delivery of a c-Myc Inhibitory Peptide Using Elastin-like Polypeptide, Drug Delivery Minisymposium, Mississippi Academy of Sciences Annual Meeting, Olive Branch, MS | 2009 |
| Poster Presentation, Bidwell, G. L. III, Benghuzzi, H., and Raucher, D. Thermally Targeted Delivery of a c-Myc Inhibitory Peptide using Elastin-like Polypeptide, Department of Defense Breast Cancer Research Program (BCRP) Leading Innovative Networking and Knowledge Sharing (LINKS) Conference, Washington, DC | 2009 |
| Poster Presentation, Bidwell, G. L. III, Davis, A.N., and Raucher, D. Targeting a Thermally Responsive c-Myc Inhibitory Polypeptide to Specific Intracellular Compartments Using Cell Penetrating Peptides, American Association for Cancer Research Annual Meeting, San Diego, CA | 2008 |
| Poster Presentation, Bidwell, G. L. III, Davis, A.N., Fokt, I., Priebe, W., and Raucher, D. An elastin-like polypeptide - Doxorubicin fusion for thermally-targeted delivery and evasion of multidrug resistance, American Association for Cancer Research Annual Meeting, Los Angeles, CA | 2007 |
| Poster Presentation, Bidwell, G.L. III and Raucher D. Enhancing toxicity of topoisomerase II inhibitors using a c-Myc inhibiting polypeptide, American Association for Cancer Research Annual Meeting, Anaheim, CA | 2005 |
| Poster Presentation, Bidwell, G.L. III and Raucher D. Enhancing antiproliferative effect of topoisomerase II inhibitors using a c-Myc inhibiting polypeptide, Mississippi Academy of Sciences Annual Meeting | 2005 |
| Poster Presentation, Massodi I., Bidwell, G. L. III, and Raucher D. Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery, Mississippi Academy of Sciences Annual Meeting | 2005 |
| Poster Presentation, Massodi I., Bidwell, G. L. III, and Raucher D. Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery, American Society for Cell Biology 44th Annual Meeting, Washington, DC | 2004 |
| Poster Presentation, Bidwell, G.L. III and Raucher D. Application of thermally responsive polypeptides directed against the c-Myc oncogene for cancer therapy, AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, MA | 2003 |
| Poster Presentation, Bidwell, G.L. III, Skertich M., and Raucher D. Targeted delivery of thermally sensitive cytotoxic polypeptides, Mississippi Academy of Sciences Annual Meeting | 2003 |
| Poster Presentation, Bidwell, G.L. III and Mossing, M.C. Energy transfer studies of folding and dimerization of lambda Cro repressor variants, Experimental Biology (FASEB) Annual Meeting, New Orleans, LA | 2002 |
Honors, Awards, and Recognition
| 1st Annual Intellectual Property Recognition (3 invention disclosures, 3 provisional patent applications, 2 non-provisional patent applications, 2 issued patents, 1 spinoff company founded), University of Mississippi Medical Center | 2019 |
| Excellence in Research Award - Gold Medal, University of Mississippi Medical Center | 2017 |
| Translational Research Team Award (with Alejandro Chade), University of Mississippi Medical Center | 2016 |
| Early Career Investigator Award, University of Mississippi Medical Center | 2015 |
| Excellence in Research Award - Silver Medal, University of Mississippi Medical Center | 2014 |
| Early Career Reviewer Program, NIH Center for Scientific Review | 2013 |
| Breast Cancer Research Program Era of Hope Conference Distinguished Postdoctoral Poster Award, Department of Defense | 2011 |
| Radiology Research Day Second Prize, University of Mississippi Medical Center | 2011 |
| Sanofi-Aventis Scholar-in-training Award, American Association for Cancer Research | 2010 |
| Excellence in Research Award - Bronze Medal, The Univeristy of Mississippi Medical Center | 2009 |
| Dean's Graduate Research Award - First Prize, The University of Mississippi Medical Center | 2007 |
| OSI Pharmaceuticals Scholar-in-Training Award, American Association for Cancer Research | 2007 |
| Taylor Medalist, University of Mississippi | 2002 |
| Undergraduate Poster Contest - First Prize, American Society for Biochemistry and Molecular Biology | 2002 |
| Alpha Epsilon Delta Scholarship, University of Mississippi | 2001 |
| Golden Key, University of Mississippi | 2000 |
| Phi Beta Kappa, University of Mississippi | 2000 |
| Phi Kappa Phi Scholarship, University of Mississippi | 2000 |
| Chancellor's Leadership Scholarship, University of Mississippi | 1998 |
| All American Scholar, University of Mississippi | 1998 |
| Chancellor's Honor Roll, University of Mississippi | 1998 |
| Mississippi Eminent Scholars Grant, University of Mississippi | 1998 |
| Robert C. Byrd Scholarship, University of Mississippi | 1998 |
Professional Membership and Service
| American Heart Association, Member | 2013 - Present |
| American Physiological Society, Member | 2012 - Present |
| American Association for Cancer Research, Member | 2003 - 2011 |
Committee Service
| Neurology Research Executive Committee, Chair | 2019 - Present |
| American Physiological Society Animal Care and Experimentation Committee, Member | 2019 - Present |
| Cancer Center and Research Institute Scientific Leadership Council, Member | 2018 - Present |
| Program in Neuroscience Admissions Committee, Member | 2017 - 2019 |
| Program in Neuroscience Curriculum Committee, Member | 2017 - 2019 |
| Program in Neuroscience Executive Committee, Member | 2016 - 2019 |
| Faculty Search Committee, University of Mississippi School of Pharmacy, Department of Pharmaceutics and Drug Delivery, Member | 2015 - 2015 |
| American Physiological Society Central Nervous System Steering Committee, Secretary/Treasurer | 2014 - 2018 |
| UMMC Experimental Models Space Committee, Member | 2013 - Present |
| UMMC Patent Committee, Member | 2013 - Present |
| MEDICAL CENTER-ANIMAL CARE AND USE, Member | 2011 - Present |
| UMMC School of Graduate Studies in the Health Sciences Alumni Board of Directors, Member | 2010 - 2013 |
Community Service
| Physiology Understanding (PhUn) Week at the MS Children's Museum Event, Volunteer | 11/2014 - 11/2014 |
| Jackson Preparatory School, Career Day-Presenter | 02/2012 - 02/2012 |
Other Service
| Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Sustained Release Drug Delivery (SRDD) Review Panel, Chair | 09/2020 - 11/2020 |
| Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Sustained Release Drug Delivery (SRDD) Discovery Award Review Panel, Panel Reviewer | 06/2020 - 07/2020 |
| NIH Special Emphasis Panel ZRG1 DKUS-L 11 B for Nephrology Small Business, Panel Reviewer | 05/2020 - 07/2020 |
| Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Sustained Release Drug Delivery (SRDD) Preapplication Review Panel, Panel Reviewer | 05/2020 - 07/2020 |
| Advanced Drug Delivery Reviews, Ad hoc reviewer | 2020 - Present |
| Cellular Signaling, Ad hoc reviewer | 2020 - Present |
| Cell Transplantation, Ad hoc reviewer | 2020 - Present |
| Heliyon, Ad hoc reviewer | 2020 - Present |
| Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Peer Review Cancer Research Program (PRCRP), Panel Reviewer | 10/2019 - 12/2019 |
| NIH Special Emphasis Panel ZRG1 DKUS-L 11 B for Nephrology Small Business, Panel Reviewer | 09/2019 - 11/2019 |
| NIH Special Emphasis Panel ZRG1 DKUS-L 11 B for Nephrology Small Business, Panel Reviewer | 05/2019 - 07/2019 |
| Netherlands Organisation for Scientific Research Vidi Talent Programme, Panel Reviewer | 2019 - 12/2019 |
| Nature Reviews Nephrology, Ad hoc reviewer | 2019 - Present |
| Circulation Research, Ad hoc reviewer | 2019 - Present |
| Stem Cells Translational Medicine, Ad hoc reviewer | 2019 - Present |
| Acta Biomaterialia, Ad hoc reviewer | 2019 - Present |
| Artificial Cells, Blood Substitutes, and Biotechnology, Ad hoc reviewer | 2019 - Present |
| ACS Applied Materials and Interfaces, Ad hoc reviewer | 2019 - Present |
| NIH NCATS ZTR1 CI-4 (02) 1 CTSA Collaborative Innovation Awards Review Meeting, Panel Reviewer | 10/2018 - 11/2018 |
| Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Sustained Release Drug Delivery (SRDD) Review Panel, Chair | 09/2018 - 11/2018 |
| EBioMedicine, Ad hoc reviewer | 2018 - Present |
| Biomaterials, Ad hoc reviewer | 2018 - Present |
| Biomedicine and Pharmacotherapy, Ad hoc reviewer | 2018 - Present |
| Genes, Ad hoc reviewer | 2018 - Present |
| Pharmaceutical Medicine, Ad hoc reviewer | 2018 - Present |
| Pharmaceutics, Ad hoc reviewer | 2018 - Present |
| NIH Genes and Drug Delivery (GDD) Study Section, Panel Reviewer | 06/2017 - 06/2017 |
| NIH Genes and Drug Delivery (GDD) Study Section, Panel Reviewer | 02/2017 - 02/2017 |
| American Heart Association Fellowship Basic Cell – Membranes and Subcellular Organelles Study Section, Panel Reviewer | 2017 - 12/2017 |
| Center of Excellence in Perinatal Research COBRE Small Grants Program, University of Mississippi Medical Center, Panel Reviewer | 2017 - Present |
| Mississippi Center for Clinical and Translational Research Small Grants Program, University of Mississippi Medical Center, Panel Reviewer | 2017 - Present |
| Neuro Institute Pilot Grants Program, University of Mississippi Medical Center, Panel Reviewer | 2017 - Present |
| Hypertension, Ad hoc reviewer | 2017 - Present |
| Clinical Science, Ad hoc reviewer | 2017 - Present |
| Journal of Controlled Release, Ad hoc reviewer | 2017 - Present |
| American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, Ad hoc reviewer | 2017 - Present |
| Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Peer Reviewed Cancer Research Program (PRCRP) Pancreatic Cancer, Panel Reviewer | 12/2016 - 12/2016 |
| NIH NICHD Special Emphasis Panel for Assessing Human Placental Development and Function Using Existing Data (Human Placenta Project), Panel Reviewer | 12/2016 - 12/2016 |
| American Heart Association Basic Cell MSO Study Section, Panel Reviewer | 10/2016 - 10/2016 |
| Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Breast Cancer Research Program (BCRP), Panel Reviewer | 06/2016 - 06/2016 |
| NIH NICHD Special Emphasis Panel/Scientific Review Group 2016/05 ZHD1 DSR-Z (50) 1 for Using Omics to Define Human Placental Development and Function Across Pregnancy (Human Placenta Project), Panel Reviewer | 03/2016 - 03/2016 |
| Interdisciplinary Research Initiation Award, University of Toledo, Panel Reviewer | 2016 - 01/2016 |
| Journal of Ocular Pharmacology and Therapeutics, Ad hoc reviewer | 2016 - Present |
| Center for Psychiatric Neuroscience COBRE Small Grants Program, University of Mississippi Medical Center, Panel Reviewer | 06/2015 - 06/2015 |
| NIH NICHD Special Emphasis Panel/Scientific Review Group 2015/08 ZHD1 DSR-Z (50/51) for Novel Tools to Assess Human Placental Structure and Function (Human Placenta Project), Panel Reviewer | 03/2015 - 03/2015 |
| Center for Obesity Research COBRE Small Grants Program, University of Mississippi Medical Center, Panel Reviewer | 01/2015 - 01/2015 |
| Pharmaceutics, Editorial Board Member | 2015 - Present |
| Nanomedicine, Ad hoc reviewer | 2015 - Present |
| Molecules, Ad Hoc Reviewer | 2015 - Present |
| NIH Xenobiotic and Nutrient Disposition and Action (XNDA) Study Section, Early Career Reviewer | 01/2014 - 01/2014 |
| Journal of Drug Targeting, Ad Hoc Reviewer | 2014 - Present |
| Biochimica et Biophysica Acta-General Subjects, Ad Hoc Reviewer | 2014 - Present |
| Proteins, Ad Hoc Reviewer | 2014 - Present |
| Cancer Research, Ad Hoc Reviewer | 2014 - Present |
| Intramural Research Support Program (IRSP), University of Mississippi Medical Center, Panel Reviewer | 2014 - Present |
| BioMed Research International, Editorial Board Member | 01/2013 - 12/2013 |
| Biomed Research International, Ad Hoc Reviewer | 2013 - Present |
| Cell and Molecular Life Sciences, Ad Hoc Reviewer | 2013 - Present |
| Anticancer Drugs, Ad Hoc Reviewer | 2013 - Present |
| Expert Opinion on Drug Delivery, Ad Hoc Reviewer | 2013 - Present |
| PLOS One, Ad Hoc Reviewer | 2013 - Present |
| Neurological Disorders and Therapy, Editorial Board Member | 2013 - Present |
| International Journal of Nanomedicine, Ad Hoc Reviewer | 2012 - Present |
| Anti-Cancer Agents in Medicinal Chemistry, Ad Hoc Reviewer | 2012 - Present |
| BMC Cancer, Ad Hoc Reviewer | 2012 - Present |
| Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Peer Review Cancer Research Program (PRCRP), Panel Reviewer | 11/2011 - 11/2011 |
| Cancer Letters, Ad Hoc Reviewer | 2011 - Present |
| Department of Basic Sciences Annual Research Grant Program for the College of Veterinary Medicine, Mississippi State University, Reviewer | 2011 - 12/2015 |
Teaching Experience
| NSCI 701, Graduate, Course, Lecturer, Principles of Neuroscience | Fall 2020 |
| Graduate, Course, Lecturer, Responsible Conduct of Research for Postdoctoral Fellows | Fall 2020 |
| PHARM 723, Graduate, Course, Lecturer, Mechanisms of Drug Action | Spring 2020 |
| NSCI 710, Graduate, Course, Lecturer, Experimental Design and Biostatistics | Spring 2020 |
| ID 714, Graduate, Course, Lecturer, Professional Skills | Spring 2020 |
| Graduate, Course, Lecturer, Responsible Conduct of Research for Postdoctoral Fellows | Fall 2019 |
| PHARM 723, Graduate, Course, Lecturer, Mechanisms of Drug Action | Spring 2019 |
| NSCI 708, Graduate, Course, Course Director, Special Topics in Neuroscience | Summer 2019 |
| NSCI 710, Graduate, Course, Lecturer, Experimental Design and Biostatistics | Spring 2019 |
| ID 714, Graduate, Course, Lecturer, Professional Skills | Spring 2019 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Spring 2019 |
| NSCI 701, Graduate, Course, Lecturer, Principles of Neuroscience | Fall 2019 |
| NSCI 708, Graduate, Course, Lecturer, Special Topics in Neuroscience | Summer 2018 |
| NSCI 708, Graduate, Course, Course Director, Special Topics in Neuroscience | Summer 2018 |
| NSCI 710, Graduate, Course, Lecturer, Experimental Design and Biostatistics | Spring 2018 |
| ID 727, Graduate, Course, Lecturer, Current Issues in Biomedical Research | Fall 2018 |
| ID 714, Graduate, Course, Lecturer, Professional Skills | Spring 2018 |
| BCH 740, Graduate, Course, Lecturer, Biochemical Methods | Fall 2018 |
| NSCI 701, Graduate, Course, Lecturer, Principles of Neuroscience | Fall 2018 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Fall 2018 |
| ID 727, Graduate, Course, Lecturer, Current Issues in Biomedical Research | Fall 2017 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Spring 2017 |
| NSCI 701, Graduate, Course, Lecturer, Principles of Neuroscience | Fall 2017 |
| BCH 740, Graduate, Course, Lecturer, Biochemical Methods | Fall 2017 |
| BCH 742, Graduate, Course, Lecturer, Research Tools in Molecular Biology | Spring 2017 |
| ID 727, Graduate, Course, Lecturer, Current Issues in Biomedical Research | Spring 2017 |
| PATH 748, Graduate, Course, Lecturer, Problems in Cancer Biology | Spring 2017 |
| NSCI 710, Graduate, Course, Lecturer, Experimental Design and Biostatistics | Spring 2017 |
| NSCI 708, Graduate, Course, Course Director, Special Topics in Neuroscience | Summer 2017 |
| ID 714, Graduate, Course, Lecturer, Professional Skills | Spring 2016 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Fall 2016 |
| NSCI 701, Graduate, Course, Lecturer, Principles of Neuroscience | Fall 2016 |
| BCH 740, Graduate, Course, Lecturer, Biochemical Methods | Fall 2016 |
| ID 714, Graduate, Course, Lecturer, Professional Skills | Spring 2015 |
| BCH 742, Graduate, Course, Lecturer, Research Tools in Molecular Biology | Spring 2015 |
| ID 721, Graduate, Course, Lecturer, Molecular Oncology | Spring 2015 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Spring 2015 |
| NSCI 701, Graduate, Course, Lecturer, Principles of Neuroscience | Fall 2015 |
| BCH 740, Graduate, Course, Lecturer, Biochemical Methods | Fall 2015 |
| BCH 740, Graduate, Course, Lecturer, Biochemical Methods | Fall 2014 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Fall 2014 |
| NSCI 701, Graduate, Course, Lecturer, Principles of Neuroscience | Fall 2014 |
| NSCI 701, Graduate, Course, Lecturer, Principles of Neuroscience | Fall 2013 |
| ID 714, Graduate, Course, Lecturer, Molecular Oncology | Spring 2013 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Spring 2013 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Fall 2012 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Spring 2011 |
| BCH 743/744, Graduate, Course, Lecturer, Cellular Biochemistry | Fall 2010 |
| Premed Portal Program, Course, Lecturer, Health Careers Opportunity Program Biochemistry | 2004 - 2005 |
| Undergraduate Lab, Course, Teaching Assistant, Undergraduate Laboratory, Department of Biology | 1999 - 2000 |
Directed Student Learning
| Supervised Research, Advised: William Doyle | 2020 - 2020 |
| Supervised Research, Advised: Hali Peterson | 2020 - Present |
| Supervised Research, Advised: Elizabeth Gordineer | 2020 - 2020 |
| Dissertation Committee Member, Advised: Katheryn Lett | 2020 - Present |
| Dissertation Committee Member, Advised: Owen Herrock | 2020 - Present |
| Dissertation Committee Chair, Advised: Adesanya Akinleye | 2020 - Present |
| Supervised Research, Advised: Loc Pham | 2019 - 2019 |
| Chair, Graduate Qualifying Exam Committee, Advised: Kendra Stansak | 2019 - 2019 |
| Supervised Research, Advised: Owen Herrock | 2019 - 2019 |
| Dissertation Committee Member, Advised: Kyle Moore | 2019 - Present |
| Dissertation Committee Member, Advised: Ciara McKnight | 2019 - Present |
| Research Advisor, An MMP-2 inhibitory biologic for treatment of renal disease Advised: Adesanya Akinleye | 2019 - Present |
| Supervised Research, Advised: Adesanya Akinleye | 2018 - 2018 |
| Supervised Research, Advised: Shelly Rae Edwards | 2018 - 2018 |
| Supervised Research, Advised: Charles Barnes | 2018 - 2018 |
| Vice Chair, Graduate Qualifying Exam Committee, Advised: Grahan Casey | 2018 - 2018 |
| Vice Chair, Graduate Qualifying Exam Committee, Advised: Carlos Zamarripa | 2018 - 2018 |
| Vice Chair, Graduate Qualifying Exam Committee, Advised: Sid Gaikwad | 2018 - 2018 |
| Vice Chair, Graduate Qualifying Exam Committee, Advised: Redin Spann | 2018 - 2018 |
| Dissertation Committee Member, Advised: Dipa Mitra | 2018 - Present |
| Dissertation Committee Member, Advised: Carlos Zamarripa | 2018 - Present |
| Dissertation Committee Chair, Advised: Jamarius Waller | 2018 - Present |
| Dissertation Committee Chair, Advised: John Aaron Howell | 2018 - Present |
| Dissertation Committee Member, Advised: Redin Spann | 2018 - 2020 |
| Dissertation Committee Member, Advised: Jason Engel | 2018 - 2020 |
| Research Advisor, The use of a biopolymer-fused form of ELP-VEGFB as a treatment for Preeclampsia Advised: Jamarius Waller | 2018 - Present |
| Research Advisor, Development of Peptide Inhibitors of Nuclear Factor Kappa B as Therapeutics for Ischemic Stroke Advised: John Aaron Howell | 2018 - Present |
| Supervised Research, Advised: John Aaron Howell | 2017 - 2017 |
| Supervised Research, Advised: Daniel MacArthur | 2017 - 2017 |
| Member, Qualifying Exam Committee, Advised: Walker Wiggins | 2017 - 2017 |
| Dissertation Committee Member, Advised: Erika Guise | 2017 - 2019 |
| Dissertation Committee Member, Advised: Jared Cobb | 2017 - 2020 |
| Dissertation Committee Member, Advised: Sonja Dragojevic | 2017 - 2019 |
| Dissertation Committee Member, Advised: Adrian Eddy | 2017 - 2019 |
| Supervised Research, Advised: Sid Gaikwad | 2016 - 2016 |
| Chair, Graduate Qualifying Exam Committee, Advised: Xiao Zhang | 2016 - 2016 |
| Dissertation Committee Member, Advised: Ramana Vaka | 2016 - 2019 |
| Dissertation Committee Member, Advised: Robert Wright | 2016 - 2018 |
| Supervised Research, Advised: Kazimir Smolenski | 2015 - 2015 |
| Supervised Research, Advised: Ezekiel Gonzalez-Fernandez | 2015 - 2015 |
| Supervised Research, Advised: Jamarius Waller | 2015 - 2015 |
| Research Advisor, Effect of Polymer Size on Pharmacokentics and Biodistribution of Elastin-like Polypeptides Advised: Marija Kuna | 2015 - 2018 |
| Supervised Research, Advised: Sonja Dragojevic | 2015 - 2015 |
| Supervised Research, Advised: Jordan Herring | 2015 - 2015 |
| Supervised Research, Advised: Leia Golden | 2015 - 2015 |
| Dissertation Committee Chair, Advised: Marija Kuna | 2015 - 2018 |
| Dissertation Committee Member, Advised: Valeria Zai-Rose | 2015 - 2018 |
| Research Advisor, Advised: Caleb Reese | 2014 - 2015 |
| Research Advisor, Delivery of Neuroprotective Growth Factors to the Central Nervous System for Treatment of Spinocerebellar Ataxia Advised: Jeremy McGowan | 2014 - 2017 |
| Dissertation Committee Chair, Advised: Jeremy McGowan | 2013 - 2017 |
| Supervised Teaching Activity, Advised: Hannah Dye | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Conner Graham | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Jordan Hester | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Kelsey Hillhouse | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Kelli Hartman | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Ashley Holyfield | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Lindsay Macher | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Brandice Palmer | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Arthi Reddy | 2013 - 2013 |
| Supervised Teaching Activity, Advised: John Suedel | 2013 - 2013 |
| Supervised Teaching Activity, Advised: Sajal Tiway | 2013 - 2013 |
| Supervised Research, Advised: Andy Danandeh | 2013 - 2013 |
| Supervised Research, Advised: Chen Liu | 2013 - 2013 |
| Research Advisor, Advised: Sarah Elizabeth Scales | 2012 - 2014 |
Fellows supervised
| T32 and AHA funded fellow, Cardiovascular-Renal Research Center, Research Advisor, 1 fellows supervised | 09/2014 - 12/2018 |