Journal Article |
| Intapad S, Tull FL, Brown AD, Dasinger JH, Ojeda NB, Fahling JM, Alexander BT. Renal Denervation Abolishes the Age-Dependent Increase in Blood Pressure in Female Intrauterine Growth-Restricted Rats at 12 Months of Age. Hypertension. 2013;61(4):828-834. | 2013 |
| Ojeda NB, Royals TP, Alexander BT. Sex differences in the enhanced responsiveness to acute angiotensin II in growth-restricted rats: Role of fasudil, a Rho kinase inhibitor. Am J Physiol Renal Physiol. 2013;304(7):F900-F907. | 2013 |
| Flynn ER, Alexander BT, Lee J, Hutchens ZM Jr, Maric-Bilkan C. High-fat/fructose feeding during prenatal and postnatal development in female rats increases susceptibility to renal and metabolic injury later in life. Am J Physiol Regul Integr Comp Physiol. 2013 Feb;304(4):R278-85. | 2013 |
| Ojeda NB, Hennington BS, Williamson DT, Hill ML, Betson NE, Sartori-Valinotti JC, Reckelhoff JF, Royals TP, Alexander BT. Oxidative stress contributes to sex differences in blood pressure in adult growth-restricted offspring. Hypertension, 2012: 60:114-122. | 2012 |
| Campbell LR, Pang Y, Ojeda NB, Zheng B, Rhodes PG, Alexander BT Intracerebral lipopolysaccharide induces neuroinflammatory change and augmented brain injury in growth-restricted neonatal rats. Pediatr Res. 2012;71(6):645-52. | 2012 |
| Jackson CM, Alexander BT, Roach L, Haggerty D, Marbury DC, Hutchens ZM, Flynn ER, Maric-Bilkan C. Exposure to maternal overnutrition and a high fat diet during early postnatal development increases susceptibility to renal and metabolic injury later in life. Am J Physiol Renal Physiol. 2012;302(6):F774-83. | 2012 |
| Ojeda NB, Intapad S, Royals TP, Black JT, Dasinger JH, Tull FL, Alexander BT. Hypersensitivity to acute angiotensin II in female growth-restricted offspring is exacerbated by ovariectomy. Am J Physiol Regul Integr Comp Physiol. 2011;301(4):1421-1427. | 2011 |
| Ojeda NB, Royals TP, Black JT, Dasinger, JH, Johnson JM, Alexander BT. Enhanced sensitivity to acute angiotensin II is testosterone dependent in adult male growth-restricted offspring. Am J Physiol Regul Integr Comp Physiol. 2010;298:1421-1427 | 2010 |
| Ojeda NB, Johnson WR, Dwyer TM, Alexander BT. Early renal denervation prevents development of hypertension in growth-restricted offspring. Clin Exp Pharmacol Physiol, 2007;34:1212-1216. | 2007 |
| Ojeda NB, Grigore D, Robertson EB, Alexander BT. Estrogen protects against increased blood pressure in postpubertal female growth restricted offspring. Hypertension. 2007; 50:679-685. | 2007 |
| Grigore D, Ojeda NB, Robertson EB, Dawson AS, Huffman C, Bourassa E, Speth RC, Brosnihan, KB, Alexander BT. Placental insufficiency results in temporal alterations in the renin angiotensin system in male hypertensive growth restricted offspring. Am J Physiol Regul Integr Comp Physiol. 2007;293(2):R804-R811. | 2007 |
| Joyner J, Neves LA, Granger JP, Alexander BT, Merrill DC, Chappell MC, Ferrario CM, Davis WP, Brosnihan KB. Temporal-spatial expression of angiotensin-(1-7) and angiotensin converting enzyme 2 in the kidney of normal and hypertensive pregnant rats. Am J Physiol Regul Integr Comp Physiol, 2007;293(1):R169-R177. | 2007 |
| Ojeda NB, Grigore D, Yanes LL, Iliescu R, Robertson EB, Zhang H, Alexander BT. Testosterone contributes to marked elevations in mean arterial pressure in adult male intrauterine growth restricted offspring. Am J Physiol Regul Integr Comp Physiol. 2007;292(2):R758-63. | 2007 |
| Alexander BT, Hendon AE, Ferril G, Dwyer TM. Renal denervation abolishes hypertension in low birth weight offspring from pregnant rats with reduced uterine perfusion. Hypertension, 2005, 45(2):754-758. | 2005 |
| Lamarca BB, Bennett WA, Alexander BT, Cockrell K, Granger JP. Hypertension Produced by Reductions in Uterine Perfusion in the Pregnant Rat. Role of Tumor Necrosis Factor-{alpha}. Hypertension, 2005; 46(4):1022-1025. | 2005 |
| Alexander BT, Llinas MT, A., Kruckeberg WC, and Granger JP L-arginine attenuates hypertension in pregnant rats with reduced uterine perfusion pressure. Hypertension, 2004;43(4):832-836. | 2004 |
| Payne JA, Alexander BT, Khalil RA. Decreased endothelium-dependent NO-cGMP vascular relaxation and hypertension in growth-restricted rats on a high-salt diet. Hypertension, 2004;43(2):420-7. | 2004 |
| Llinas MT, Alexander BT, Capparelli MF, Carroll MA and Granger JP. Cytochrome P-450 inhibition attenuates hypertension and renal vasoconstriction induced by chronic reductions in uterine perfusion pressure in pregnant rats. Hypertension, 2004;43(3):623-628. | 2004 |
| Moore LE, Wallace KL, Alexander BT, May WL, Thigpen BD, Bennett WA. Reduced placental perfusion causes an increase in maternal serum leptin. Placenta, 2003;24(8-9):877-81. | 2003 |
| Sedeek MH, Llinas MT, Drummond H, Fortepiani L, Abram SR, Alexander BT, Reckelhoff JF, and Granger JP. Role of reactive oxygen species in endothelin-induced hypertension. Hypertension, 2003;42(4):806-10. | 2003 |
| Alexander, BT. Placental insufficiency leads to development of hypertension in growth restricted offspring. Hypertension, 2003;41(3):457-462. | 2003 |
| Payne JA, Alexander BT, and Khalil RA. Reduced endothelial vascular relaxation in growth-restricted offspring of pregnant rats with reduced uterine perfusion. Hypertension. 2003;42(4):768-74. | 2003 |
| Llinas MT, Alexander BT, Seedek M, Abram SR, Crell A, and Granger JP. Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant rats. Am J Hypertens, 2002;15(9):793-797. | 2002 |
| Alexander BT, Cockrell K.L., Cline FD, and Granger JP. Inducible nitric oxide synthase inhibition attenuates renal hemodynamics during pregnancy. Hypertension, 2002;39(2 Pt 2):586-590. | 2002 |
| Davis JR, Giardina JB, Green GM, Alexander BT, Granger JP, and Khalil RA. Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant rats. Am J Physiol Regul Integr Comp Physiol, 2002;282(2):R390-R399. | 2002 |
| Alexander BT, Cockrell KL, Massey M.B, Bennett WA, and Granger JP. Tumor necrosis factor-alpha induced hypertension in pregnant rats results in decreased renal neuronal nitric oxide synthase expression. Am J Hypertens, 2002;15(2 Pt 1):170-175. | 2002 |
| Alexander BT, Cockrell K, Cline FD, Llinas MT, Sedeek M, and Granger JP. Effect of angiotensin II synthesis blockade on the hypertensive response to chronic reductions in uterine perfusion pressure in pregnant rats. Hypertension, 2001;38:742-745. | 2001 |
| Abram SR, Alexander BT, Bennett WA, Granger JP. Role of neuronal nitric oxide synthase in mediating renal hemodynamic changes during pregnancy Am J Physiol Regul Integr Comp Physiol, 2001;281(5):R1390-1393. | 2001 |
| Alexander BT, Rinewalt AN, Cockrell KL, Bennett WA, and Granger JP. Endothelin type A receptor blockade attenuates the hypertension in response to chronic reductions in uterine perfusion pressure. Hypertension, 2001;37(2 Part 2):485-489. | 2001 |
| Alexander BT. Cockrell KL, Rinewalt AN, Herrington JN, and Granger JP. Enhanced renal expression of preproendothelin mRNA during chronic angiotensin II hypertension. Am J Physiol Regul Integr Comp Physiol, 2001;280(5):R1388-R1392. | 2001 |
| Kanashiro CA, Cockrell KL. Alexander BT, Granger JP, and Khalil RA. Pregnancy-associated reduction in vascular protein kinase C activity rebounds during inhibition of NO synthesis. American Journal of Physiology Integr Comp Physiol, 2001;278(2): R295-303. | 2001 |
| Alexander BT, Kassab SE, Miller MT, Abram SR, Reckelhoff JF, Bennett WA, and Granger JP. Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide. Hypertension, 2001;37(4):1191-1195. | 2001 |
| Gunjan A, Alexander BT, Sittman DB, Brown DT. Effects of H1 histone variant overexpression on chromatin structure. J Biol Chem. 1999 274(53):37950-6. | 1999 |
| Kanashiro CA, Alexander BT, Granger JP, and Khalil RA. Ca2+-insensitive vascular protein kinase C during pregnancy and NOS inhibition. Hypertension, 1999;34(2):924-930. | 1999 |
| Alexander BT, Miller TM, Kassab S, Novak J, Reckelhoff JF, Kruckeberg WC, and Granger JP. Differential expression of renal nitric oxide synthase isoforms during pregnancy in rats. Hypertension, 1999;33(part II):435-439. | 1999 |
| Brown DT, Gunjan A, Alexander BT, Sittman DB. Differential effect of H1 variant overproduction on gene expression is due to differences in the central globular domain. Nucleic Acids Res. 1997;25(24):5003-9. | 1997 |
| Brown DT, Alexander BT, Sittman DB. Differential effect of H1 variant overexpression on cell cycle progression and gene expression. | 1996 |
Olson MO, Rivers ZM, Thompson BA, Kao WY, Case ST.
Note Dr. Alexander has published under the name BA Thompson. Interaction of nucleolar phosphoprotein C23 with cloned segments of rat ribosomal deoxyribonucleic acid. Biochemistry. 1983;22(14):3345-51. | 1983 |
Pao CC, Dyess BT.
Note that Dr. Alexander has published under the name BT Dyess. Effect of unusual guanosine nucleotides on the activities of some Escherichia coli cellular enzymes. Biochim Biophys Acta. 1981;677(3-4):358-62. | 1981 |
Pao CC, Dyess BT.
Note that Dr. Alexander has published under the name BT Dyess. Regulation of small RNAs in Escherichia coli. Alteration in the intracellular concentrations of small RNAs during amino acid and energy starvation. Biochim Biophys Acta. 1981;653(1):1-8. | 1981 |
| Pao CC, Dyess BT. Stringent control of RNA synthesis in the absence of guanosine 5'-diphosphate-3'-diphosphate. J Biol Chem. 1981;256(5):2252-7. | 1981 |
| Pao CC, Fleckenstein J, Dyess BT. Role of peptide chain elongation factor G in guanosine 5'-diphosphate 3'-diphosphate synthesis. J Bacteriol. 1981;145(1):429-33. | 1981 |
| Maric-Bilkan C, Symonds M, Ozanne S, Alexander BT. Impact of maternal obesity and diabetes on long-term health of the offspring. Exp Diabetes Res. 2011:163438 | 2011 |
| Alexander BT Gender medicine in the field of developmental origins of adult disease. Gend Med. 2010;7(5):379-380. | 2010 |
| Alexander BT. Mentoring Forum: Early years and planning for tenure review. The Physiologist. 2008;51(2):64-65. | 2008 |
Review Article |
| Intapad S, Ojeda NB, Dasinger JH, Alexander BT. Sex differences in the developmental origins of cardiovascular disease. Physiology. 2014;29(2):122-132. | 2014 |
| 1. Ojeda NB, Intapad S, Alexander BT. Sex differences in the developmental programming of hypertension. Acta Physiol (Oxf). 2013 Nov 23. doi: 10.1111/apha.12206. [Epub ahead of print] | 2013 |
| Paixão AD, Alexander BT How the Kidney Is Impacted by the Perinatal Maternal Environment to Develop Hypertension. Biol Reprod. 2013 [in press] | 2013 |
| Intapad S, Alexander BT. Pregnancy Complications and Later Development of Hypertension. Curr Cardiovasc Risk Rep. 2013, 7:183-189. | 2013 |
| Nuyt AM, Alexander BT. Developmental programming of hypertension. Curr Opin Nephrol Hypertens. 2009;18(2):144-52. | 2009 |
| Ojeda NB, Grigore D, Alexander BT. Developmental programming of hypertension: Insight from animal models of nutritional manipulation. Hypertension. 2008;52:44-50. | 2008 |
| Ojeda NB, Grigore D, Alexander BT. Intrauterine growth Restriction: Fetal programming of hypertension and kidney disease. Adv Chronic Kidney Dis. 2008;15(2):101-106. | 2008 |
| LaMarca BB, Alexander BT, Gilbert JS, Ryan MJ, Sedeek M, Murphy SR, Granger JP. Pathophysiology of Hypertension in Response to Placental Ischemia during Pregnancy: A Central Role for Endothelin? Gend Med. 2008; 5(Suppl A): S133-S138. | 2008 |
| Ojeda NB, Grigore D, Alexander BT. Role of fetal programming in the development of hypertension. Future Cardiol. 2008;4(2):163-174. | 2008 |
| Grigore D, Ojeda NB, Alexander BT. Sex differences in the fetal programming of hypertension. Gend Med., 2008; 5(Suppl A): S121-S132. | 2008 |
| Ojeda NB, Grigore D, Hennington BS, Alexander BT. Prenatal programming of hypertension. Brazilian Journal of Hypertension. 2008;15(1):3-8. | 2008 |
| Alexander, BT Fetal Programming of Hypertension Am J Physiol; 2006;290(1):R1-R10. | 2006 |
| Granger JP, Alexander BT, Llinas M. Mechanisms of pressure natriuresis. Curr Hypertens Rep, 2002;4(2):152-159. | 2002 |
| Granger JP, Alexander BT, Llinas MT, Bennett WA, and Khalil RA. Pathophysiology of preeclampsia: linking placental ischemia/hypoxia with microvascular dysfunction. Microcirculation, 2002;9:147-160. | 2002 |
| Granger JP, Alexander BT, Llinas MT, Bennett WA, and Khalil RA. Pathophysiology of hypertension during preeclampsia linking placental ischemia with endothelial dysfunction. Hypertension, 2001;38(3 Pt 2):718-722. | 2001 |
| Granger JP, Alexander BT, Bennett WA, and Khalil RA. Pathophysiology of pregnancy-induced hypertension. Am J Hypertens, 2001;14(6):178S-185S. | 2001 |
| Alexander BT, Bennett WA, Khalil RA, and Granger JP. Preeclampsia: linking placental ischemia with cardiovascular-renal dysfunction. News Physiol Sci, 2001;16:282-286. | 2001 |
| Granger JP and Alexander BT. Abnormal pressure-natriuresis in hypertension: role of nitric oxide. Acta Physiol Scand, 2000;168(1):161-168. | 2000 |
| Granger JP and Alexander BT. Pathogenesis of pregnancy-induced hypertension. Current concepts in hypertension, 1999;3(4):5-6 | 1999 |
| Olson MO, Thompson BA. Distribution of proteins among chromatin components of nucleoli. Biochemistry. 1983;22(13):3187-93. | 1983 |
Abstracts |
| Intapad S, Dasinger JH, Backstrom MA, Alexander BT. Blockade of the renin angiotensin system abolishes age-dependent hypertension in female intrauterine growth restricted rats in the absence of an enhanced sensitivity to acute angiotensin II. 2014 The FASEB J, 1085.2 | 2014 |
| Dasinger JH, Intapad S, Backstrom MA, Alexander BT. Age impacts the developmental programming of blood pressure regulation in the intrauterine growth-restricted male rat. 2014 The FASEB J, 1085.10 | 2014 |
| Ryan MJ, Sasser JM, Alexander BT Kidney, Heart, Lung PhUn at the Mississippi Children’s Museum, 2014 The FASEB J | 2014 |
| Intapad S, Warrington JP, Spradley FT, Palei A, Drummond HE, Ryan MJ, Granger JP, Alexander BT. A reduction in uterine perfusion pressure induces hypertension during pregnancy in the mouse. 2014 The FASEB J, 1084.5 | 2014 |
| Intapad S, Brown AD, Tull FL, Fahling JM, Dasinger JH, Ojeda NB, Alexander BT. Renal denervation abolishes age-dependent hypertension in female intrauterine growth restricted rats. The FASEB J, 2013. | 2013 |
| Intapad S, Brown AD, Tull FL, Fahling JM, Dasinger JH, Ojeda NB, Alexander BT. Impaired pancreatic function contributes to the age-dependent development of metabolic syndrome in female intrauterine growth restricted rats. The FASEB J, 2013. | 2013 |
| Intapad S, Brown AD, Tull FL, Dasinger JH, Ojeda NB, Alexander BT. A Postnatal Diet Rich in Fat and Sucrose Leads to the Differential Alterations in Renal Function and Metabolic Health in Male Control and Intrauterine Growth Restricted Offspring. Hypertension. 2012;60:A18. | 2013 |
| Intapad S, Fahling JM, Alexander BT. Age impacts circulating testosterone levels in male intrauterine growth restricted rats leading ot glucose intolerance and alterations in programmed hypertension. Hypertension. 2013, A218. | 2013 |
| tapad S, Brown AD, Tull FL, Dasinger JH, Ojeda NB, Alexander BT. A Postnatal Diet Rich in Fat and Sucrose Leads to the Differential Alterations in Renal Function and Metabolic Health in Male Control and Intrauterine Growth Restricted Offspring. Hypertension. 2012;60:A18. | 2012 |
| Bettye Sue Hennington, Norma B. Ojeda, Danielle T Williamson, Melanie L Hill, Nicole E.E. Betson, and Barbara T. Alexander Sex differences in antioxidant capacity contributes to hypertension in adult intrauterine growth restricted offspring FASEB J 2012 26:lb838 | 2012 |
| Suttira Intapad, L Fred Tull, Andrew D Brown, John Henry Dasinger, Norma B Ojeda, and Barbara T Alexander Intrauterine growth restriction induces a greater susceptibility to hypertension and metabolic dysfunction with aging in female growth-restricted rats FASEB J 2012 26:1101.4 | 2012 |
| Norma Beatriz Ojeda, Steven Wilkening, John Dasinger, Barbara T Alexander, Glen Graves, and Phil Rhodes Antioxidant treatment during development prevents low birth weight, hypertension, and enhanced sensitivity to mild renal ischemia in offspring exposed to placental insufficiency FASEB J 2012 26:1101.1 | 2012 |
| Royals TP, Ojeda NB, Manigrasso MB, Tucci MA, Alexander BT. Response of bone remodeling biomarkers following ovariectomy in female intrauterine growth restricted rats. 2011, J Bone Miner Res 26(Suppl 1): SU0395 | 2011 |
| Intapad, S., Tull, FL., Dasinger, JH., Ojeda, NB., Alexander, BT. Differential programming of endothelin receptor expression contributes to sex differences in adult blood pressure regulation in intrauterine growth restricted offspring. The Physiologist, 2011;54(6):4.27. | 2011 |
| Glenn T, Intapad S, Tull FL, Lin RCS, Alexander BT, Paul IA. Perinatal exposure to an SSRI antidepressant programs sex difference in adult cardiovascular risk in rodent offspring. The Physiologist, 2011;54(6):4.23. | 2011 |
| S Intapad, FL Tull, JH Dasinger, JT Black, NB Ojeda, BT Alexander. Sex-specific mechanisms contribute to the pressor response to acute angiotensin II in a rat model of intrauterine growth restriction. The FASEB J, 2011 25:1029.6 | 2011 |
| Christine Maric, Jonathan Lee, Zachary M Hutchens, Barbara T Alexander, and Elizabeth R Flynn Exposure to maternal obesity and a high fat diet during early postnatal development increases susceptibility to renal injury later in life. The FASEB J; 2011 25:836.2 | 2011 |
| S Intapad, JM Wiseman, FL Tull, JH Dasinger, JT Black, NB Ojeda, C Maric, BT Alexander. A mismatch of fetal and postnatal nutrition leads to sex dependent differences in postnatal growth and blood glucose levels. Experimental Biology Meeting, Washington DC 2011. A mismatch of fetal and postnatal nutrition leads to sex dependent differences in postnatal growth and blood glucose levels. FASEB J 2011 25:1029.5 | 2011 |
| Melanie L. Hill, Andrew Perkins, Erdogan Memili, Barbara T. Alexander, and Bettye Sue Hennington Regulation of NOS enzymes by splice variants FASEB J 2011 25:1029.9 | 2011 |
| Bettye Sue Hennington, Danielle Marie Trocquet, LaTeia S. Taylor, Melanie Hill, Norma Ojeda, and Barbara T Alexander Chronic L-NAME leads to differential expression of renal NOS isoform and renal antioxidant expression in control and intrauterine growth restricted rats. The FASEB J 2011 25:1029.10 | 2011 |
| Intapad, S., Tull, FL., Dasinger, JH., Fan, F., Roman, RJ., Ojeda, NB., Alexander, BT. 20-HETE contributes to hypersensitivity to acute angiotensin II in intrauterine growth restricted rats. Hypertension, 2011;58:e33-e183. | 2011 |
| Campbell L, Pang Y, Zheng B, Ojeda B, Rhodes PG, Alexander BT. Neuroinflammation and brain damage following intracerebral lipopolysaccharide insult in growth restricted rat pups. Neuroscience 2010 S-10022 SfN. | 2010 |
| Maric C, Roach L, Haggerty D, Richard A, Marbury DC, Alexander BT. Impact of maternal diabetes on short- and long-term renal injury in the offspring. FASEB J 2010;812.2. | 2010 |
| Ojeda NB, Romero DG, Dasinger, JH, Alexander BT, Rhodes P. Aldosterone levels are inversely correlated to superoxide dismutase activity in the low birth weight newborn. FASEB J 2010;629.6 | 2010 |
| Ojdea NB, Royals TP, Alexander BT. Ovariectomy induces an enhanced sensitivity to angiotensin II in female growth restricted rats. FASEB J 2010;1041.8. | 2010 |
| Hennington BS, Jones EJ, Taylor L, Trocquet DM, Ojeda NB, Royals TP, Alexander BT. Bioavailability of nitric oxide is impaired in hypertensive male IUGR offspring. FASEB J 2010; 1041.7 | 2010 |
| Alexander BT, Royals TP, Ojeda NB. Enhanced responsiveness to angiotensin II is androgen dependent in a rodent model of intrauterine growth restriction induced by placental insufficiency. The Physiologist 2009; 1041.8. | 2009 |
| Hennington BS, Dawson A, NB Ojeda, TP Royals, BT Alexander. Oxidant status is maintained through different mechanisms in male and female intrauterine growth restricted offspring. The FASEB J. 2009. | 2009 |
| Ojeda NB, Royals TP, BT Alexander. Endothelin receptor blockade abolishes acute angiotensin II sensitivity in intrauterine growth restricted rats The FASEB J. 2009. | 2009 |
| Campbell LR, Zheng B, Ojeda NB, Royals TP, Rhodes PG, Pang Y, BT Alexander. Intrauterine growth restriction inhibits cell proliferation within the subventricular zone and white matter of rat offspring. The FASEB J. 2009. | 2009 |
| Ojeda NB, Royals TP, Alexander BT. Sensitivity to angiotensin II contributes to sex differences in a model of fetal programming of hypertension. Hypertension. 2008, 52:e34-e131 (P282). | 2008 |
| Llinas MT, Alexander BT, Capparelli M, Carroll MA, Granger JP. Role of CYP-450 metabolites of arachidonic acid during pregnancy induced hypertension in rat American Journal of Hypertension, Vol. 15, 4, 2002. | 2008 |
| Grigore D, Ojeda NB, Alexander BT Estrogen is nephroprotective in the rat remnant kidney in a rat model of intrauterine growth restriction. The FASEB J. 2008; 22:941.6. | 2008 |
| Grigore D, Ojeda NB, LaMarca BB, Alexander BT. Inflammatory cytokines are elevated in intrauterine growth restricted offspring in response to placental insufficiency. The FASEB J. 2008; 22:923.6. | 2008 |
| Ojeda NB, Grigore D, Royals TP, Alexander BT. Susceptibility to renal injury is increased in a rat model of intrauterine growth restriction. The FASEB J. 2008; 22: 941.5. | 2008 |
| Ojeda NB, Royals TP, Alexander BT. Responsiveness to acute angiotensin II is increased in intrauterine growth restricted rats. The FASEB J. 2008; 22:735.7. | 2008 |
| Norma B Ojeda, Julio C Sartori-Valinotti, Daniela Grigore, Elliott B Robertson, Barbara T Alexander. Chronic administration of tempol abolishes programmed hypertension induced by placental insufficiency in the rat. Hypertension 2007;50(4):e78. | 2007 |
| Daniela Grigore, Norma B Ojeda, Elliott B Robertson, Barbara T Alexander. Chronic ETA receptor blockade attenuates hypertension in intrauterine growth restricted offspring. Hypertension 2007;50(4):e109. | 2007 |
| Norma Ojeda, Daniela Grigore, Elliott B. Robertson Barbara T. Alexander. Estradiol has protective effects on female growth restricted offspring in a model of programmed hypertension. Faseb J ; 2007; 21(6, Pt II):A1417. | 2007 |
| Norma Ojeda, Daniela Grigore, Elliott B. Robertson Barbara T. Alexander. Tempol abolishes hypertension induced by ovariectomy in a model of programmed hypertension. Faseb J 2007; 21(6, Pt II):A1417. | 2007 |
| Daniela Grigore, Norma Ojeda, Elliott B. Robertson, Barbara T. Alexander. Up-regulation of renal ACE2 is associated with gender differences in a model of fetal programming of hypertension induced by placental insufficiency. Hypertension 2006;48(4):e25, P5. | 2006 |
| Norma Ojeda, Daniela Grigore, Elliott B. Robertson Barbara T. Alexander. Ovariectomy induces hypertension in adult growth restricted female offspring in a model of fetal programming due to placental insufficiency. Hypertension 2006;48(4):e25, P10. | 2006 |
| Ojeda N, Grigore D, Robertson EB, Alexander BT. Sex differences in fetal programming of hypertension. The FASEB J, 2006;20(5, Pt 2):A1191. | 2006 |
| Dawson AS, Ojeda N, Grigore D, Robertson EB, and Alexander BT. Effect of early inhibition of the renin angiotensin system on the development of hypertension in a model of low birth weight induced by reduced uterine perfusion in the pregnant rat. The FASEB J, 2006;20(4, Pt 1):A758. | 2006 |
| Grigore D, Ojeda N, Robertson EB, Alexander BT. Hypertension in adult growth restricted offspring is associated with activation of the renal renin angiotensin system. The FASEB J, 2006;20(4, Pt 1):A757. | 2006 |
| Llinas M, Wallukat G, Dechend R, Mueller DN, Luft FC, Alexander BT, LaMarca B, Granger JP. Agonistic autoantibodies to the At1 receptor in a rat model of preeclampsia induce by chronic reductions in uterine perfusion pressure. Hypertension. 2005; 46:884. | 2005 |
| Ojeda N, Johnson WR, and Alexander BT. Early renal denervation abolishes hypertension in low birth weight offspring from pregnant rats with reduced uterine perfusion. FASEB J. 2005;19(5):A1586. | 2005 |
| Alexander BT, Hendon AE, Dwyer TM. Renal denervation abolishes hypertension in low birth weight offspring from pregnant rats with reduced uterine perfusion. Hypertension, 2004;44(4):500. | 2004 |
| Alexander BT and Hendon AE. Hypertension in low birth weight offspring from pregnant rats with reduced uterine perfusion is associated with a reduction in pressure natriuresis. FASEB J, 2004;18(4):A738. | 2004 |
| Alexander BT and Hendon AE. Angiotensin II type 1 receptor antagonism attenuates hypertension in low birth weight offspring from pregnant rats with reduced uterine perfusion. FASEB J, 2004;18(4):A737. | 2004 |
| Granger, JP, Rinewalt AN, Llinas MT and Alexander BT. Effects of hypercholesterolemia on the blood pressure response to reductions in uterine perfusion pressure in pregnant rats. FASEB J, 2004;18(4):A742. | 2004 |
| Sedeek MH, Alexander BT, Sholook MM, Chandler, DL, Abram SR, and Granger JP. Renal cortical NADPH oxidase and superoxide dismutase activity in response to reduced uterine perfusion pressure in pregnant rats. FASEB J, 2004;18(4):A740. | 2004 |
| Payne JA, Alexander BT, and Khalil RA. Reduced endothelium-dependent NO-cGMP vascular relaxation and hypertension in growth-restricted rats on high salt diet. Hypertension, 2003; 42(3):393. | 2003 |
| Alexander BT, Llinas MT, Rinewalt AN, Brosnihan KB, Neves LA, and Granger JP. Chronic reductions in uterine perfusion pressure in the pregnant rat results in marked elevations in arterial pressure and increased sensitivity to angiotensin II. Scientific Meeting of the Inter-American Society of Hypertension, Program Book, 2003;119. | 2003 |
| Alexander BT, and Hendon AE. Converting enzyme inhibition attenuates the hypertension in low birth weight offspring from pregnant rats with reduced uterine perfusion. FASEB J. 2003;17:A486. | 2003 |
| Llinas MT, Alexander BT, Cockrell K, Balzli C, and Granger JP. Angiotensin AT1 receptor blockade prevents the hypertension in response to chronic reductions in uterine perfusion pressure in pregnant rats. FASEB J. 2003;17:A487. | 2003 |
| Abram SR, Alexander BT, Llinas MT, Sedeek M, and Granger JP. Hypertension induced by chronic endothelin type B (ETB) receptor blockade attenuates the production of renal medullary nitric oxide in rats. Hypertension, 2002;40(3):406. | 2002 |
| Llinas MT, Alexander BT, Sedeek M, Abram S, and Granger JP. Enhanced renal cortical expression of COX-1 and COX-2 isoforms during pregnancy. Hypertension, 2002;40(3):425. | 2002 |
| Alexander BT, Steijen CL, and Cockrell K A reduction in uterine perfusion pressure in the pregnant rat results in low birth weight offspring predisposed to development of hypertension. FASEB J, 2002;16(5),Pt. 2:A686. | 2002 |
| Rinewalt AN, Llinas MT, Alexander BT, Granger JP. Effects of hypercholesterolemia on blood pressure during pregnancy in rats. FASEB J, 2002;6(5), Pt. 2: A868. | 2002 |
| Llinas MT, Alexander BT, Capparelli MF, Carroll MA, Granger JP. Role of CYP450 metabolites of arachidonic acid(CYP450-AA metabolites) in a rat model of preeclampsia. FASEB J,l 2002:16(5), Pt. 2: A868. | 2002 |
| Alexander BT, Cockrell K, and Granger JP. Inducible nitric oxide synthase inhibition attenuates relaxin-induced increases in renal hemodynamics in non-pregnant rats. FASEB J, 2002;16(5),Pt. 2:A686. | 2002 |
| Abram SA, Alexander BT, Llinas MT, Sedeek M, Granger JP. Endothelin Type B (ETB) receptor blockade-induced hypertension during changes in dietary sodium intake: Role of nitric oxide. FASEB J, 2002;16(5), Pt. 2: A838. | 2002 |
| Alexander BT, Llinas MT, and Granger JP. L-arginine supplementation attenuates the hypertension produced in response to chronic reductions in uterine perfusion pressure in the pregnant rat. FASEB J, 2002;16(5),Pt. 2:A686. | 2002 |
| Alexander BT, Cockrell KL, Cline FD, and Granger JP. Inducible nitric oxide synthase inhibition attenuates renal hemodynamics during normal pregnancy. Hypertension, 2001;38:499. Hypertension, 2001;38:499. | 2001 |
| Granger JP, Alexander BT, Abram SR, Reckelhoff JF, Wilson J, and Rinewalt AN. Chronic reductions in uterine perfusion pressure in the pregnant rat produces hypertension and reduces pressure-natriuresis. Hypertension, 2001;37(3):1013. | 2001 |
| Alexander BT, Cockrell KL, Sedeek M, and Granger JP. Role of the renin-angiotensin system in meditating the hypertension produced by chronic reductions in uterine perfusion pressure in the pregnant rat. Hypertension, 2001;37(3):986. | 2001 |
| Sedeek MH, Alexander BT, Sholook MM, Chandler, DL, Abram SR, and Granger JP. Renal cortical NADPH oxidase and superoxide dismutase activity in response to reduced uterine perfusion pressure in pregnant rats. FASEB J, 2004;18(4):A740. | 2001 |
| Llinas MT, Alexander BT, Abram SR, Sedeek M, and Granger JP. Enhanced production of thromboxane A2 in response to chronic reductions in uterine perfusion pressure in pregnant rats. FASEB J, 2001;15(5 part II):A788. | 2001 |
| Alexander BT, Kline F, Abram SR, Sedeek M, and Granger JP. Blockade of the renin-angiotensin system does not alter the hypertension produced by chronic reductions in uterine perfusion pressure in the pregnant rat. FASEB J, 2001;15(4 part I):A136. | 2001 |
| Abram SR, Alexander BT, Sedeek M, and Granger JP. Role of endothelin type B receptors in modulating the chronic hypertensive effects of angiotensin II. FASEB J, 2001;15(4 part I):A136.. | 2001 |
| Sedeek M, Alexander BT, Abram SR, and Granger JP. Role of oxidative stress in endothelin-induced hypertension in rats. FASEB J, 2001;15(5 part II):A785. | 2001 |
| Granger JP, Cockrell KL, Rinewalt AN, and Alexander BT. Endothelin-B receptors play an important role in modulating chronic pressure-natriuresis and blood pressure regulation in response to changes in dietary sodium intake. Hypertension, 2000;36(4):682. | 2000 |
| Alexander BT, Rinewalt AN, Massey MB, Bennett WA, and Granger JP. Endothelin-A Receptor Blockade Attenuates the Hypertension in a Rat Model of Pregnancy-Induced Hypertension. Hypertension, 2000;36(4):679. | 2000 |
| Sirous ZN, Cockrell KL, Alexander BT, Granger JP, and Khalil RA. TNF-alpha induced hypertension in pregnant rats is associated with increased [Ca2+] signaling in renal arterial smooth muscle. Hypertension, 2000;36(4):688. | 2000 |
| Alexander BT, Rinewalt AN, Bennett WM, and Granger JP. The hypertensive response to chronic reductions in uterine perfusion pressure is associated with elevated renal expression of preproendothelin. Am J Hypertension, 2000;13(4): 244A. | 2000 |
| Murphy JG, Fleming JB, Alexander BT, Granger JP, and Khalil RA. Increased [Ca2+] signaling in renal arterial smooth muscle cells during inhibition of nitric oxide synthesis in pregnant rats. FASEB J, 2000;114(4): A137. | 2000 |
| Granger JP, Alexander BT, Rinewalt AN, Herrington JN, and Opgenorth TJ. Role of endothwlin in mediating the chronic renal and hypertensive actions of angiotensin II (ANG II) in rats. FASEB J, 2000;114(4):A656. | 2000 |
| Alexander BT, Massey MB, Cockrell KL, Bennett WA, and Granger J P. Elevations in plasma TNFalpha in pregnant rats decreases renal nNOS and iNOS and results in hypertension. FASEB J, 2000;114(4):A137. | 2000 |
| Alexander BT, Cockrell KL, Herrington JN, and Granger JP. Enhanced renal expression of preproendothelin mRNA during chronic Angiotensin II hypertension. Hypertension, 1999;34(2):362. | 1999 |
| Granger JP, Bennett WM, Alexander BT, Cockrell K., and Whitworth NS. Long-term elevation of plasma TNF-alpha increases arterial pressure and reduces kidney function in pregnant rats. Hypertension, 1999;34(2):337. | 1999 |
| Alexander BT, Kassa, SE, Abrams SR, Reckelhoff JF, and Granger JP. Renal protein expression of neuronal NOS is reduced in a rat model of pregnancy-induced hypertension. Hypertension, 1999;34(2):368. | 1999 |
| Kassab S, Alexander BT, Miller TM, Reckelhoff JF, and Granger JP. Bilateral renal function responses to chronic endothelin-A receptor antagonism in two-kidney, one-clip Goldblatt hypertensive rats. Hypertension, 1999;33(5):1290. | 1999 |
| Alexander BT, Herrington JN, Kassab S, Reckelhoff JF, and Granger JP. Role of nitric oxide in a rat model of pregnancy-induced hypertension. Hypertension, 1999;33(5):1252. | 1999 |
| Alexander BT, Herrington JN, Kassab S, Reckelhoff JF, and Granger JP. Nitric oxide production in a rat model of pregnancy-induced-hypertension. FASEB J, 1999;13(5):788.17. | 1999 |
| Abram SR, Alexander BT, Cockrell KL, Herrington JN, and Granger JP. Role of neuronal nitric oxide synthase (nNOS) in mediating renal hemodynamic changes during pregnancy. FASEB J, 1999;13 (5):788.16. | 1999 |
| Granger JP, Cockrell K, Kassab S, and Alexander BT. Endothelin-A receptor antagonism attenuates the acute renal actions of angiotensin II in conscious rats. Hypertension, 1998;32(2):623. | 1998 |
| Alexander BT, Reckelhoff JF, Kassab S, and Granger JP. Differential expression of renal nitric oxide synthase isoforms during pregnancy. Hypertension, 1998;32(2): 622. | 1998 |
| Alexander BT, Reckelhoff JF, Kassab S, and Granger JP Expression of renal endothelial nitric oxide (NO) synthases (eNOS) during pregnancy in rats. FASEB J, 1998;12(4):A53. | 1998 |
| Alexander BT, Brown DT, and Sittman DB. Effects of overexpression of histone H1o on chromatin structure. Mol Biol Cell, 1995;6:75a. | 1995 |
| Brown DT, Alexander BT, and Sittman DB. Transient inhibition of DNA replication in H1 variant-overproducing cell lines is associated with a high H1/nucleosome ratio. Mol Biol Cell, 1993;4:397a. | 1993 |
Book Chapter |
| Ojeda NB, Grigore D, Alexander BT. Developmental programming of hypertension by placental insufficiency. In: Developmental Programming of Diabetes and Metabolic Syndrome Transworld Research Network. Marlon Cerf, Editor. 2008, pp 51-66. | 2008 |
Book |
| Barbara T Alexander Developmental Programming of Cardiovascular Disease Morgan and Claypool | 2013 |
Editorial Commentary |
| Hennington BS, Alexander BT. Linking IUGR and Blood Pressure: Insight into the Human Origins of Cardiovascular Disease. Circulation. 2013;128(20):2179-80. | 2013 |
| Intapad S, Alexander BT Activation of the sympathetic nervous system, is it key to the developmental origins of enhanced cardiovascular risk? Am J Physiol Renal Physiol. 2013 In Press. | 2013 |
| Intapad S, Alexander BT. Future Cardiovascular Risk: Interpreting the Importance of Increased Blood Pressure during Pregnancy. Circulation. 2013;127(6):668-9. | 2013 |
| Intapad S, Alexander BT. The double hit of growth restriction: its origins and outcome on this generation and the next. J Physiol. 2012;590(Pt 5):1019. doi: 10.1113/jphysiol.2011.226720 | 2012 |
| Alexander BT, Intapad S. Preterm Birth: A Novel Risk Factor for Higher Blood Pressure in Later Life. Hypertension 2012;59(2):189-910 | 2012 |
| Alexander BT Early life exposure to hypoxia: a developmental insult critical to the programming of cardiovascular risk. Am J Hypertens. 2010;23(11):1158. | 2010 |
| Alexander BT Epigenetic changes in gene expression. Focus on "The Liver X-Receptor (LXR) gene promoter is hypermethylated in a mouse model of prenatal protein restriction" Am J Physiol Regul Integr Comp Physiol. 2009;298(2):R272-274. | 2010 |
| Alexander BT Is maternal blood pressure the key to vascular dysfunction in preterm offspring with elevated blood pressure? Hypertension. 2010;56(1):34-35 | 2010 |
| Alexander BT Developmental programming of sex-dependent alterations in lipid metabolism: A role for long-term, sex-specific alterations in LDL receptor expression. Am J Physiol Regul Integr Comp Physiol. 2009;296(4):R1027-8. | 2009 |
| Alexander BT, Ojeda NB. Prenatal inflammation and the early origins of hypertension. Clin Exp Pharmacol Physiol. 2008;35(12):1403-4. | 2008 |
| Alexander BT, Ojeda NB Slow pre-natal growth; accelerated post-natal growth: Critical influences on adult blood pressure. Hypertension. 2008;52:1-2. | 2008 |
| Alexander BT. Divergent origins of slow fetal growth. Relevance to adult cardiovascular disease. Hypertension. 2007;50(3):465-466. | 2007 |
| Alexander BT. Divergent pathways of programming: Pre-natal versus post-natal protein undernutrition. Am J Physiol Regul Integr Comp Physiol. 2007;293(3):R1257-1258. | 2007 |
| Alexander BT. Pre-natal influences and endothelial dysfunction: a link between reduced placental perfusion and preeclampsia Hypertension, 2007;49(4):775-6. | 2007 |
| Alexander, BT. Intrauterine growth restriction and reduced glomerular number: role of apoptosis. Am J Physiol Regul Integr Comp Physiol, 2003;285(5):R933-4. | 2003 |
Editorial |
| Simon C. Langley-Evans, 1Barbara Alexander, Harry J. McArdle, and Deborah M. Sloboda Developmental origins of health and disease. J Nutr Metab. 2012:838640 | 2012 |
