Heng Zeng, MD

Heng Zeng, MD

Assistant Professor

Department:
SOM-Pharmacology/Toxicology

Email:
hzeng@umc.edu

Work Phone:
(601) 984-1611

Biography

After receiving M.D. Degree in medical school from the University of South China in 1987, Dr. Zeng worked as a Surgeon at the Department of Surgery of Hengyang Medical First Hospital for ten years. In 1997, she came to U.S. A, to study postdoctoral training at Southern Illinois University School of Medicine. In 1999-2011, she worked at Vanderbilt University Medical Center. She joined the University of Mississippi Medical Center in 2011. She has been an assistant professor at the Department of Pharmacology and Toxicology since 2020.
Her research interest focuses on elucidating the novel roles of the mitochondrial frataxin-Sirtuin 3-TIGAR signaling pathway and mitochondrial ferroptosis/iron-sulfur cluster that regulate vascular endothelial metabolisms, mitochondrial dysfunction, and heart failure of diabetic cardiomyopathy, cardiomyopathy of Friedreich’s Ataxia by using endothelial-specific knockout, cardiomyocyte-specific knockout mouse models. She is also interested in gender differences in pressure-induced coronary autoregulation in heart failure.

Education

University of South China, MD, Medicine1987
University of Southern Illinois, USA , School of Medicine, postdoctoral, Pharmacology

Current Positions

Assistant Professor, School of Medicine07/2020 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Scientist, University of Mississippi Medical Center, School of Medicine, Department of Pharmacology / Toxicology09/2011 - 06/2020
Scientist, Vanderbilt University, School of Medicine, Department of Pediatrics07/2005 - 08/2011
Research Associate, Vanderbilt University, School of Medicine, Department of Medicine10/1999 - 06/2005
Postdoctoral fellow, South Illinois University, School of Medicine, Department of Pharmacology / Toxicology10/1997 - 09/1999
Assistant Professor, University of South China, School of Medicine, Department of Surgery07/1987 - 09/1997

Sponsored Program Funding

Extramural, Coronary microvascular dysfunction and diastolic dysfunction in diabetes, NHLBI10/2025 - 09/2029
Extramural, Inactivation of Sirtuin 3-mediated TIGAR in heart of Friedreich's ataxia, NHLBI10/2025 - 09/2029
Extramural, Coronary Microvascular Dysfunction in Friedreich's Ataxia, NHLBI07/2025 - 06/2029
Intramural, p53 acetylation in microvascular rarefaction and heart failure, UMMC11/2023 - 11/2025
Extramural, p53 acetylation in microvascular rarefaction and heart failure, NHLBI09/2022 - 08/2024
Extramural, Endothelial glucose metabolism and Coronary microvascular dysfunction in aged female, P20NIH/GM104357 pilot grant12/2021 - 04/2023
Extramural, Endothelial PHD2 in hypertensive vascular remodeling, NHLBI09/2021 - 08/2025
Extramural, Coronary microvascular rarefaction in diabetic/obese heart, NHLBI03/2017 - 02/2022

Publications

Journal Article

He X, Cantrell AC, Williams QA, Gu W, Chen Y, Chen JX, Zeng H, p53 Acetylation Exerts Critical Roles in Pressure Overload-Induced Coronary Microvascular Dysfunction and Heart Failure in Mice. Arteriosclerosis, thrombosis, and vascular biology, 2024 Apr;44(4):826-8422024
Cantrell AC, Zeng H, Chen JX, The Therapeutic Potential of Targeting Ferroptosis in the Treatment of Mitochondrial Cardiomyopathies and Heart Failure. Journal of cardiovascular pharmacology, 2024 Jan 1;83(1):23-322024
He X, Williams QA, Cantrell AC, Besanson J, Zeng H, Chen JX, TIGAR Deficiency Blunts Angiotensin-II-Induced Cardiac Hypertrophy in Mice. International journal of molecular sciences, 2024 Feb 19;25(4)2024
Pan L, He X, Xu R, Bhattarai U, Niu Z, do Carmo J, Sun Y, Zeng H, Clemmer JS, Chen JX, Chen Y, Endothelial specific prolyl hydroxylase domain-containing protein 2 deficiency attenuates aging-related obesity and exercise intolerance. GeroScience, 2024 Aug;46(4):3945-39562024
Cantrell AC, Besanson J, Williams Q, Hoang N, Edwards K, Bishop GR, Chen Y, Zeng H, Chen JX, Ferrostatin-1 specifically targets mitochondrial iron-sulfur clusters and aconitase to improve cardiac function in Sirtuin 3 cardiomyocyte knockout mice. Journal of molecular and cellular cardiology, 2024 Jul;192:36-472024
Liu B, Zeng H, Su H, Williams QA, Besanson J, Chen Y, Chen JX, Endothelial Cell-Specific Prolyl Hydroxylase-2 Deficiency Augments Angiotensin II-Induced Arterial Stiffness and Cardiac Pericyte Recruitment in Mice. Journal of the American Heart Association, 2024 Aug 20;13(16):e0357692024
Bhattarai U, Xu R, He X, Pan L, Niu Z, Wang D, Zeng H, Chen JX, Clemmer JS, Chen Y, High selenium diet attenuates pressure overload-induced cardiopulmonary oxidative stress, inflammation, and heart failure. Redox biology, 2024 Oct;76:1033252024
Chen JX, Zhang J, Chen Y, Zeng H, Knockout of Sirtuin 3 in endothelial cells impairs endothelial-dependent relaxation and myogenic response in mice. Physiological reports, 2024 Oct;12(20):e700602024
Chen JX, Li L, Cantrell AC, Williams QA, Zeng H, High Glucose Activates Prolyl Hydroxylases and Disrupts HIF-α Signaling via the P53/TIGAR Pathway in Cardiomyocyte. Cells, 2023 Mar 31;12(7)2023
Su H, Cantrell AC, Chen JX, Gu W, Zeng H, SIRT3 Deficiency Enhances Ferroptosis and Promotes Cardiac Fibrosis via p53 Acetylation. Cells, 2023 May 19;12(10)2023
He X, Cantrell AC, Williams QA, Gu W, Chen Y, Chen JX, Zeng H, P53 Acetylation Exerts Critical Roles In Pressure Overload Induced Coronary Microvascular Dysfunction and Heart Failure. bioRxiv : the preprint server for biology, 2023 Feb 9;2023
He X, Cantrell AC, Williams QA, Chen JX, Zeng H, TIGAR deficiency sensitizes angiotensin-II-induced renal fibrosis and glomerular injury. Physiological reports, 2022 Apr;10(8):e152342022
He X, Zeng H, Cantrell AC, Williams QA, Chen JX, Knockout of TIGAR enhances myocardial phosphofructokinase activity and preserves diastolic function in heart failure. Journal of cellular physiology, 2022 Aug;237(8):3317-33272022
He X, Zeng H, Cantrell AC, Chen JX, Regulatory role of TIGAR on endothelial metabolism and angiogenesis. Journal of cellular physiology, 2021 Nov;236(11):7578-75902021
Su H, Cantrell AC, Zeng H, Zhu SH, Chen JX, Emerging Role of Pericytes and Their Secretome in the Heart. Cells, 2021 Mar 4;10(3)2021
Li L, Zeng H, He X, Chen JX, Sirtuin 3 Alleviates Diabetic Cardiomyopathy by Regulating TIGAR and Cardiomyocyte Metabolism. Journal of the American Heart Association, 2021 Feb;10(5):e0189132021
Zeng H, He X, Chen JX, A Sex-Specific Role of Endothelial Sirtuin 3 on Blood Pressure and Diastolic Dysfunction in Female Mice. International journal of molecular sciences, 2020 Dec 21;21(24)2020
Feng X, Su H, He X, Chen JX, Zeng H, SIRT3 Deficiency Sensitizes Angiotensin-II-Induced Renal Fibrosis. Cells, 2020 Nov 20;9(11)2020
Su H, Zeng H, He X, Zhu SH, Chen JX, Histone Acetyltransferase p300 Inhibitor Improves Coronary Flow Reserve in SIRT3 (Sirtuin 3) Knockout Mice. Journal of the American Heart Association, 2020 Sep 15;9(18):e0171762020
Zhao Y, Zeng H, Liu B, He X, Chen JX, Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury. American journal of physiology. Renal physiology, 2020 Aug 1;319(2):F345-F3572020
Zeng H, He X, Chen JX, Endothelial Sirtuin 3 Dictates Glucose Transport to Cardiomyocyte and Sensitizes Pressure Overload-Induced Heart Failure. Journal of the American Heart Association, 2020 Jun 2;9(11):e0158952020
Su H, Zeng H, Liu B, Chen JX, Sirtuin 3 is essential for hypertension-induced cardiac fibrosis via mediating pericyte transition. Journal of cellular and molecular medicine, 2020 Jul;24(14):8057-80682020
Zeng H, Chen JX, Sirtuin 3, Endothelial Metabolic Reprogramming, and Heart Failure With Preserved Ejection Fraction. Journal of cardiovascular pharmacology, 2019 Oct;74(4):315-3232019
He X, Zeng H, Chen JX, Emerging role of SIRT3 in endothelial metabolism, angiogenesis, and cardiovascular disease. Journal of cellular physiology, 2019 Mar;234(3):2252-22652019
He X, Zeng H, Roman RJ, Chen JX, Inhibition of prolyl hydroxylases alters cell metabolism and reverses pre-existing diastolic dysfunction in mice. International journal of cardiology, 2018 Dec 1;272:281-2872018
He X, Zeng H, Chen ST, Roman RJ, Aschner JL, Didion S, Chen JX, Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction. Journal of molecular and cellular cardiology, 2017 Nov;112:104-1132017
Wang S, Zeng H, Chen ST, Zhou L, Xie XJ, He X, Tao YK, Tuo QH, Deng C, Liao DF, Chen JX, Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice. Journal of cellular and molecular medicine, 2017 Sep;21(9):1967-19782017
Tao YK, Zeng H, Zhang GQ, Chen ST, Xie XJ, He X, Wang S, Wen H, Chen JX, Notch3 deficiency impairs coronary microvascular maturation and reduces cardiac recovery after myocardial ischemia. International journal of cardiology, 2017 Jun 1;236:413-4222017
Wang S, Zeng H, Xie XJ, Tao YK, He X, Roman RJ, Aschner JL, Chen JX, Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling. Oncotarget, 2016 Sep 13;7(37):58848-588612016
He X, Zeng H, Chen JX, Ablation of SIRT3 causes coronary microvascular dysfunction and impairs cardiac recovery post myocardial ischemia. International journal of cardiology, 2016 Jul 15;215:349-572016
Zeng H, He X, Tuo QH, Liao DF, Zhang GQ, Chen JX, LPS causes pericyte loss and microvascular dysfunction via disruption of Sirt3/angiopoietins/Tie-2 and HIF-2α/Notch3 pathways. Scientific reports, 2016 Feb 12;6:209312016
Hou X, Zeng H, Tuo QH, Liao DF, Chen JX, Apelin Gene Therapy Increases Autophagy via Activation of Sirtuin 3 in Diabetic Heart. Diabetes research (Fairfax, Va.), 2015 Oct;1(4):84-912015
Zeng H, Vaka VR, He X, Booz GW, Chen JX, High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss. Journal of cellular and molecular medicine, 2015 Aug;19(8):1847-562015
Hou X, Zeng H, He X, Chen JX, Sirt3 is essential for apelin-induced angiogenesis in post-myocardial infarction of diabetes. Journal of cellular and molecular medicine, 2015 Jan;19(1):53-612015
Zeng H, He X, Hou X, Li L, Chen JX, Apelin gene therapy increases myocardial vascular density and ameliorates diabetic cardiomyopathy via upregulation of sirtuin 3. American journal of physiology. Heart and circulatory physiology, 2014 Feb 15;306(4):H585-972014
Li L, Zeng H, Chen JX, Apelin-13 increases myocardial progenitor cells and improves repair postmyocardial infarction. American journal of physiology. Heart and circulatory physiology, 2012 Sep 1;303(5):H605-182012
Chen JX, Zeng H, Reese J, Aschner JL, Meyrick B, Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model. American journal of physiology. Heart and circulatory physiology, 2012 Feb 15;302(4):H1003-122012
Tuo QH, Xiong GZ, Zeng H, Yu HD, Sun SW, Ling HY, Zhu BY, Liao DF, Chen JX, Angiopoietin-1 protects myocardial endothelial cell function blunted by angiopoietin-2 and high glucose condition. Acta pharmacologica Sinica, 2011 Jan;32(1):45-512011
Erez A, Nagamani SC, Shchelochkov OA, Premkumar MH, Campeau PM, Chen Y, Garg HK, Li L, Mian A, Bertin TK, Black JO, Zeng H, Tang Y, Reddy AK, Summar M, O'Brien WE, Harrison DG, Mitch WE, Marini JC, Aschner JL, Bryan NS, Lee B, Requirement of argininosuccinate lyase for systemic nitric oxide production. Nature medicine, 2011 Nov 13;17(12):1619-262011
Vadivel A, Aschner JL, Rey-Parra GJ, Magarik J, Zeng H, Summar M, Eaton F, Thébaud B, L-citrulline attenuates arrested alveolar growth and pulmonary hypertension in oxygen-induced lung injury in newborn rats. Pediatric research, 2010 Dec;68(6):519-252010
Fike CD, Pfister SL, Slaughter JC, Kaplowitz MR, Zhang Y, Zeng H, Frye NR, Aschner JL, Protein complex formation with heat shock protein 90 in chronic hypoxia-induced pulmonary hypertension in newborn piglets. American journal of physiology. Heart and circulatory physiology, 2010 Oct;299(4):H1190-2042010
Aschner JL, Zeng H, Kaplowitz MR, Zhang Y, Slaughter JC, Fike CD, Heat shock protein 90-eNOS interactions mature with postnatal age in the pulmonary circulation of the piglet. American journal of physiology. Lung cellular and molecular physiology, 2009 Mar;296(3):L555-642009
Tuo QH, Zeng H, Stinnett A, Yu H, Aschner JL, Liao DF, Chen JX, Critical role of angiopoietins/Tie-2 in hyperglycemic exacerbation of myocardial infarction and impaired angiogenesis. American journal of physiology. Heart and circulatory physiology, 2008 Jun;294(6):H2547-572008
Zeng H, Ornatowska M, Joo MS, Sadikot RT, TREM-1 expression in macrophages is regulated at transcriptional level by NF-kappaB and PU.1. European journal of immunology, 2007 Aug;37(8):2300-82007
Aschner JL, Foster SL, Kaplowitz M, Zhang Y, Zeng H, Fike CD, Heat shock protein 90 modulates endothelial nitric oxide synthase activity and vascular reactivity in the newborn piglet pulmonary circulation. American journal of physiology. Lung cellular and molecular physiology, 2007 Jun;292(6):L1515-252007
Chen JX, Zeng H, Tuo QH, Yu H, Meyrick B, Aschner JL, NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation. American journal of physiology. Heart and circulatory physiology, 2007 Apr;292(4):H1664-742007
Sadikot RT, Zeng H, Azim AC, Joo M, Dey SK, Breyer RM, Peebles RS, Blackwell TS, Christman JW, Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2. European journal of immunology, 2007 Apr;37(4):1001-92007
Chen JX, Zeng H, Lawrence ML, Blackwell TS, Meyrick B, Angiopoietin-1-induced angiogenesis is modulated by endothelial NADPH oxidase. American journal of physiology. Heart and circulatory physiology, 2006 Oct;291(4):H1563-722006
Sadikot RT, Zeng H, Joo M, Everhart MB, Sherrill TP, Li B, Cheng DS, Yull FE, Christman JW, Blackwell TS, Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa. Journal of immunology (Baltimore, Md. : 1950), 2006 Apr 15;176(8):4923-302006
Everhart MB, Han W, Parman KS, Polosukhin VV, Zeng H, Sadikot RT, Li B, Yull FE, Christman JW, Blackwell TS, Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation. Journal of leukocyte biology, 2005 Feb;77(2):173-802005
Sadikot RT, Zeng H, Yull FE, Li B, Cheng DS, Kernodle DS, Jansen ED, Contag CH, Segal BH, Holland SM, Blackwell TS, Christman JW, p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia. Journal of immunology (Baltimore, Md. : 1950), 2004 Feb 1;172(3):1801-82004
Chen JX, Zeng H, Chen X, Su CY, Lai CC, Induction of heme oxygenase-1 by Ginkgo biloba extract but not its terpenoids partially mediated its protective effect against lysophosphatidylcholine-induced damage. Pharmacological research, 2001 Jan;43(1):63-92001
Zeng H, Chen JX, Microvascular Rarefaction and Heart Failure With Preserved Ejection Fraction. Frontiers in cardiovascular medicine, 2019;6:15
Zhou LY, Zeng H, Wang S, Chen JX, Regulatory Role of Endothelial PHD2 in the Hepatic Steatosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018;48(3):1003-1011
Zeng H, Chen JX, Conditional knockout of prolyl hydroxylase domain protein 2 attenuates high fat-diet-induced cardiac dysfunction in mice. PloS one, 2014;9(12):e115974
Zeng H, Li L, Chen JX, Loss of Sirt3 limits bone marrow cell-mediated angiogenesis and cardiac repair in post-myocardial infarction. PloS one, 2014;9(9):e107011
Li L, Zeng H, Hou X, He X, Chen JX, Myocardial injection of apelin-overexpressing bone marrow cells improves cardiac repair via upregulation of Sirt3 after myocardial infarction. PloS one, 2013;8(9):e71041
Zeng H, Li L, Chen JX, Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts. PloS one, 2012;7(4):e35905
Chen JX, Tuo Q, Liao DF, Zeng H, Inhibition of protein tyrosine phosphatase improves angiogenesis via enhancing Ang-1/Tie-2 signaling in diabetes. Experimental diabetes research, 2012;2012:836759
Caito S, Zeng H, Aschner JL, Aschner M, Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS. PloS one, 2014;9(5):e98161
He X, Xu R, Pan L, Bhattarai U, Liu X, Zeng H, Chen JX, Hall ME, Chen Y, Inhibition of NK1.1 signaling attenuates pressure overload-induced heart failure, and consequent pulmonary inflammation and remodeling. Frontiers in immunology, 2023;14:1215855

Presentations

Platform Presentations, Endothelial Phd2 Deficiency Impairs Endothelial-Dependent Relaxation And Promotes Coronary, International Vascular Biology Meeting - IVBM, Amsterdam, Netherlands07/2024
State/Local Invited Seminars/Lectures, P53 acetylation in cardiac fibrosis microvascular dysfunction, and heart failure in mice, Department of Pharmacology, Department of Pharmacology, UMMC02/2024
Poster Presentation, Deficiency Of Sirtuin 3 In Endothelium Reduces Endothelial-Dependent Relaxation And Impairs Myogenic Response In Coronary And Middle Cerebral Arteries Of Mice., AHA, Philadelphia. PA11/2023
Poster Presentation, Endothelial Phd2 Deficiency Promotes Angiotensin-Ii-Induced Arterial Stiffness And Coronary Microvascular Dysfunction., NAVB, Newport, Ri10/2023
Poster Presentation, Treatment with PFKFB3 inhibitor potentially improves diastolic function and arterial stiffness in PHD2ECKO mice., APS Physiology, Long Beach, LA04/2023
State/Local Invited Seminars/Lectures, Sex differences of endothelial Sirt3 in Angiotensin-II induced perivascular fibrosis and cardiac dysfunction., Department of Pharmacology, Department of Pharmacology, UMMC02/2023
Platform Presentations, Sex differences of endothelial Sirt3 in Angiotensin-II induced perivascular fibrosis and cardiac dysfunction, External Advisory Board (EAC) meeting, UMMC09/2022
Poster Presentation, Ferrostatin-1 Ameliorates Cardiac Dysfunction in a Cardiomyocyte-Specific SIRTUIN 3 Knockout Mouse Model., AHA hypertension meeting, San Diego, CA09/2022
Poster Presentation, Regulatory Role Of Endothelial Phd2 On Hypertensive Arterial Stiffness And Vascular Calcification. Vascular Discovery: From Genes to Medicine, Scientific Sessions, Seattle, WA05/2022
Poster Presentation, Treatment with PFKFB3 inhibitor potentially improves diastolic function and arterial stiffness in PHD2ECKO mice., APS Physiology, Long Beach, LA04/2022
Poster Presentation, Novel Regulatory Role Of SIRT3 On Cardiomyocyte Mitochondrial Frataxin And Ferroptosis., Experimental Biology Meeting, Philadelphia, PA04/2022
State/Local Invited Seminars/Lectures, Sirt3 deficiency in blood pressure, diastolic dysfunction, and renal fibrosis. Department of Pharmacology, Department of Pharmacology, Department of Pharmacology, UMMC02/2022
Platform Presentations, DEFICIENCY OF SIRTUIN3 DISRUPTS ENDOTHELIAL GLUCOSE METABOLISM AND SENSITIZES PRESSURE OVERLOAD­INDUCED HEART FAILURE, AHA Scientific sessions, philadelphia, PA11/2019
Platform Presentations, Role of p53 acetylation in mediating myocardial angiogenesis and diabetic cardiomyopathy., AHA BCVS meeting, Boston, MA08/2019
Poster Presentation, Deficiency of sirtuin 3 accentuates angiotensin ii-induced arterail stiffness/myocardial fibrosis and hypertension., Experimental Biology, Orlando, Florida04/2019
Platform Presentations, regulatory role of endothelial sirt3 on blood pressure and diastolic dysfunction in a female mice., AHA council on hypertension, Chicago, IL09/2018
Poster Presentation, ablation of endothelial sirt3 exacerbates pressure overload-induced heart failure., AHA BCVS meeting, San Antonio08/2018
Platform Presentations, Sirtuin 3 attenuates diabetic cardiomyopathy via suppression of p53 acetylation and regulating cardiomyocyte metabolism., Experimental Biology, San Diego04/2018
Poster Presentation, Deletion of endothelial Sirt3 causes diastolic dysfunction, AHA council on hypertension, San Francisco, CA09/2017
Poster Presentation, Treatment with Prolyl Hydroxylase Inhibitor Reverses Pre-Existing Diastolic Dysfunction in the Aged SIRT3 Knockout Mice, EB meeting, Chicago04/2017
Poster Presentation, Deletion of Endothelial Sirt3 Causes Coronary Microvascular Dysfunction and HFpEF., Experimental Biology, San Diego, CA04/2016
Poster Presentation, Sirt3 regulates oxygen sensors and blood vessel formation in the heart., AHA, New Orleans, LA09/2013
Platform Presentations, Sirt3 is essential for apelin-gene therapy mediated cardiac repair in post-myocardial infarction of diabetes., AHA meeting, New orleans09/2013
Poster Presentation, SIRT3 Deficiency Impairs Hypoxic Signaling, Reprograms Basal Glycolytic Metabolism and Exacerbates Myocardial Ischemic Injury, Experimental Biology, Boston, MA04/2013
Poster Presentation, Apelin-13 Increases Myocardial Progenitor Cells and Improves Myocardial Remodeling of Post-myocardial, AHA meeting, New orleans09/2012
Poster Presentation, Apelin Reduces Myocardial Infarction Size and Promotes Angiogenesis by Increasing SDF-1/CXCR4 and AKT/eNOS/VEGF pathways, AHA meeting, Dallas07/2012
Poster Presentation, Regulation Of Sirt3 And Autophagy By Bone Marrow Cells Therapy Improves Cardiac Repair In Post-myocardial Infarction Mice, AHA meeting, Dallas07/2012
Poster Presentation, Ang-1 reduces myocardial infarction via upregulation of SDF-1/CXCR4 and recruiting hematopoietic progenitor cells in the diabetic db/db mouse model., AHA meeting, Orlando, FL11/2011
Platform Presentations, Hypoxia/reoxygenation-induced myocardial angiogenesis: Role of NADPH oxidase derived reactive oxygen species (ROS), AHA meeting, CIRCULATION 114: 155-155; 2006., AHA meeting, Chicago11/2006
Poster Presentation, Role of NADPH oxidase-derived reactive oxygen species (ROS) in angiopoietin-1-induced angiogenesis, FASEB JOURNAL 18: A385-A385; 2004., EB meeting, Washington DC03/2004

Honors, Awards, and Recognition

Excellence in Research Award (Bronze), The University of Mississippi Medical Center2023

Professional Membership and Service

North American Vascular Biology organization, Member2023 - Present
American Physiology Society, Member2023 - Present
AHA, Member2020 - Present

Committee Service

Mentor member of Dr. Joey's T32 training grant, Member2023 - Present
Cardiac Discussion group, Member2023 - Present
cardiac grant review member, Member2023 - Present
Co-Mentor, PhD student's Dissertation Committee Member, Member2020 - Present

Other Service

Digital Chinese Medicine05/2024 - Present
International Journal of Medical Sciences05/2024 - Present
Journal of Advanced Research05/2024 - Present
JoVE Journal09/2023 - Present

Teaching Experience

4, Medicine, Small Group, Facilitator, pharmacology small groupFall 2021 - 2021

Directed Student Learning

Research Advisor, Advised: Ziru Niu2024 - Present
Supervised Research, Advised: Jacob Hearin2024 - 2024
Supervised Research, Advised: Kendall Curry2023 - 2023
Supervised Research, Advised: Savanna Sheppard2023 - 2023
Supervised Research, Advised: Bryce Little2023 - 2023
Dissertation Committee Member, Endothelial PHD2 in heart failure
Advised: Quinesha Williams		2021 - Present
Dissertation Committee Member, Targeting ferroptosis in mitochondrial cardiomyopathy
Advised: Aubrey C Cantrell		2020 - 2024
Research Advisor, Advised: Ubong S Ekperikpe2019 - 2019
Research Advisor, Advised: Nathan E campbell2019 - 2019
Supervised Research, The role of pericyte in hypertensive heart failure
Advised: Han Su		2018 - 2020
Research Advisor, Advised: Sumit Sontakke2017 - 2017
Research Advisor, The role of mitochondrial oxidative stress in the pathophysiology of Preeclampsia
Advised: Venkata Ramana Vaka		2014 - 2015
Research Advisor, The Role of Endothelial SIRT3 in Cardiac Hypertrophy and Heart Failure
Advised: Xiaochen He		2012 - 2017

Fellows supervised

Research Advisor, 12 fellows supervised, G754, G32510/2011 - 12/2024