Jose Subauste, MD
Professor
Department:
SOM-Medicine-ENDO
Email:
jsubauste@umc.edu
Work Phone:
(601) 984-5525
Education
| University of Michigan, Fellowship, Endocrinology and Metabolism | 1995 |
| Southern Illinois University, Springfield, IL., Residency, Internal Medicine | 1991 |
| Southern Illinois University, Springfield, IL., Internship, Internal Medicine | 1989 |
| University of Alabama, Clerkship, Clerkship | 1988 |
| Universidad Peruana Cayetano Heredia; Lima, Peru, MD, Medicine | 1987 |
Specialty Certification Licensure
| Certification, DEA - Controlled Substance Registration Certificate, Drug Enforcement Administration | |
| Certification, Endocrinology and Metabolism, ABIM | 2009 - Present |
| Certification, ECFMG | 07/1987 - Present |
| Licensure, Mississippi State Board of Medical Licensure, State of Mississippi | 1987 - Present |
| Licensure, Endocrinology and Metabolism, ABIM | 10/1998 - 12/2008 |
| Certification, Internal Medicine, ABIM | 09/1992 - 09/2002 |
Current Positions
| Professor, School of Medicine, Department of Medicine | 07/2013 - Present |
| Professor, School of Medicine, Department of Medicine | 2008 - Present |
| Fellowship Program Director, School of Medicine, Department of Medicine | 2003 - Present |
| Staff Physician, School of , Department of Medicine | 1995 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Academic Appointments or Other Previous Appointments
| Associate Professor, University of Mississippi Medical Center, School of Medicine, Department of Medicine | 2001 - 2008 |
| Assistant Professor, University of Mississippi Medical Center, School of Medicine, Department of Medicine | 1995 - 2001 |
Sponsored Program Funding
| Intramural, Identification and Characterization of a Retinoic Acid Response Element in SHP gene, Intramural Research Support Program-UMC | 01/2008 - 12/2009 |
| Intramural, Dimerization and dominant negative activity of v-erbA, VA Merit Award | 04/2004 - 03/2008 |
| Intramural, Mineralocorticoid receptor and MBPc interaction: Potential role in cardiac remodeling, IRSP - University of Mississippi | 11/2003 - 10/2004 |
| Intramural, V-erbA: DNA binding specificity and function, VA Merit Award | 04/1998 - 03/2001 |
| Intramural, V-erbA: DNA binding specificity and function, Biomedical Research Support Grant of the University of MS Medical Center | 01/1997 - 12/1997 |
Publications
Journal Article | |
| Melcescu E, Phillips J, Moll JG, Subauste JS, Koch CA 11beta-hydroxylase deficiency and other syndromes of mineralocorticoid excess as a rare cause of endocrine hypertension Horm Metab Res 2012; in press | 2012 |
| Ungnapatanin N, Subauste JS, Henderson HM, Koch CA Endocrine aspects in patients infected with the immunodeficiency virus J Miss State Med Assoc 2012; IN PRESS | 2012 |
| East HE, Subauste JS, Gandhi A, Koch CA Secondary causes of diabetes mellitus J Miss State Med Assoc 2012; IN PRESS | 2012 |
| French SE, Subauste JS, Geraci SA Calcium abnormalities in hospitalized patients Southern Medical Journal. 2012; 105:231-237 | 2012 |
| Ventura-Holman T, Mamoon A, Subauste MC, Subauste J The effect of oncoprotein v-erbA on T3-regulated genes in hepatocytes abd their potential role in hepatocellular carcinoma Mol Biol Rep. 2011; 38:1137-1144 | 2011 |
| Chaithongdi N, Subauste J, Koch CA, Geraci S Diagnosis and management of hyperglycemic emergencies Hormones. 2011; 10 | 2011 |
| Newman BD, Maher JF, Subauste JS, Uwaifo GI, Bigler SA, Koch CA Clustering of sebaceous gland carcinoma, papillary thryoid carcinoma, and breast cancer in a woman as a new cancer susceptibility disorder: a case report Journal of Medical Case Reports, 2009; 3:6905-6910 | 2009 |
| Subauste MC, Ventura-Holman T, Du L, Subauste JS, Chan SL, Yu VC, Maher JM RACK1 downregulates levels of the pro-apoptotic protein Fem1b- in apoptosis-resistant colon cancer cells Cancer Biol. Ther. 2009; 8:2297-2305 | 2009 |
| Gerstein HC, Subauste JS Action to Control Cardiovascular Risk in Diabetes Study Group N Eng J Med. 2008; 358: 2545-2559 | 2008 |
| Ventura-Holman T, Mamoon A, Subauste JS Modulation of expression of RA-regulated genes by the oncoprotein v-erbA Gene. 2008; 425: 23-27 | 2008 |
| Mamoon A, Ventrua-Holman T, Maher JM, Subauste JS Retinoic acid responsive genes in the murine hepatocyte cell line AML 12 Gene. 2008; 408: 95-103 | 2008 |
| Ventura-Holman T, Mamoon A, Maher JF, Subauste JS Thyroid hormone responsive genes in the murine hepatocyte cell line AML 12 Gene, 2007 Jul; 396(2):332-7 | 2007 |
| Lu D, Ventura-Holman T, Li J, McMurray RW, Subauste JS, Maher JF Abnormal glucose homeostasis and pancreatic islet function in mice with inactivation of the Fem1b gene Mol Cell Biol. 2005; 25: 6570-6577 | 2005 |
| Maher JF, Hines RS, Futterweit W, Crawford S, Lu D, Shen P, Oefner P, Kazi M, Wilson JG, Subauste JS, Cowan BD Fem1a is a candidate gene for polycystic ovary syndrome Gynecol Endocrinol. 2005; 21: 330-335 | 2005 |
| Ventura-Holman T, Hahn H, Subauste JS, Maher JF The Fem1a gene is down-regulated in rhabdomyosarcoma Tumour Biol. 2005; 26: 294-9 | 2005 |
| Bratton MR, Gomez-Sanchez EP, Gomez-Sanchez CE, Subauste JS The myosin binding protein is a novel mineralocorticoid receptor binding partner Mol Cell Endocrinol 2004; 217:243-249 | 2004 |
| Zubkova I, Subauste JS V-erbA homodimers mediate the potent dominant negative activity of v-erbA on everted repeats Mol Biol Reports. 2004; 31: 131-137 | 2004 |
| Zubkova I, Subauste JS Sequences required for the transition from monomeric to homodimeric forms of thyroid hormone receptor alpha and v-erbA Mol Cell Endocrinol. 2003; 199: 61-72 | 2003 |
| Zubkova I, Subauste JS Dimerization of v-erbA on inverted repeats Biochem Biophys Res Commun. 2002; 294: 35-41 | 2002 |
| Shen Q, Subauste JS Dimerization interfaces of v-erbA homodimers and heterodimers with RXR x J Biol Chem. 2000; 275: 41018-41027 | 2000 |
| Subauste JS, Koenig, RJ Characterization of the DNA binding and dominant negative activity of v-erbA homodimers Mol Endocrinol. 1998; 12: 1380-1392 | 1998 |
| Subauste JS, Koenig RJ Comparison of the DNA binding specificity and function of v-erbA and thyroid hormone receptor J Biol Chem. 1995; 270: 7957-7962 | 1995 |
| Yang YZ, Subauste JS, Koenig RJ Retinoid X receptor x binds with the highest affinity to an imperfect direct repeat response element Endocrinology. 1995; 136: 2896-2903 | 1995 |
| Katz RW, Subauste JS, Koenig RJ The interplay of half-site sequence and spacing on the activity of direct repeat thyroid hormone response elements J Biol Chem. 1995; 270: 5238-5242 | 1995 |
| Subauste JS, Katz RW, Koenig RJ DNA binding specificity and function of retinoid X receptor x J Biol Chem. 1994; 269: 30232-30237 | 1994 |
Abstracts | |
| Phillips J, Melcescu E, Moll G, Subauste JS, Chaithongdi N, Koch CA 11B-hydroxylase deficiency: a rare cause of endocrine hypertension in blacks J Invest Med 2012; 60(1):278 | 2012 |
| Mamoon A, Ventura-Holman T, Subauste C, Subauste J Anti-apoptotic effects of retinoids in non-transformed hepatocytes Proceedings of the 4th Annual Department of Medicine Research Day, 2008, April:26 | 2008 |
| Oswalt C, Cook G, Riche D, Dale D, Subauste J Familial combined hyperlipidemia in the veteran population Proceedings of the 4th annual department of medicine research day, April 2008:5 | 2008 |
| Ventura-Holman T, Mamoon A, Subauste J Modulation of expression of RA-regulated genes by the oncoprotein verba Proceedings of the 4th annual department of medicine research day, April 2008:23 | 2008 |
| Ventura-Holman T, Mamoon A, Nanduri B, Subauste J Regulation of thyroid hormone responsive genes by the oncoprotein verba in the murine hepatocyte cell line AML 12 Proceedings of the 4th annual deparment of medicine research day, April 2008:24 | 2008 |
Thesis | |
| Subauste S Ulcerative Colitis: A Clinical, Radiological and Pathological Correlation in 19 Cases | 1987 |
Book Chapter | |
| Subauste JS, Schteingart DE The Endocrine Paraneoplastic Syndromes - Current Diagnosis 9th Edition Saunders, 1997 | 1997 |
Presentations
| Poster Presentation, 11B-hydroxylase deficiency: a rare cause of endocrine hypertension in blacks, 2012 Southern Regional Meeting, New Orleans, LA | 02/2012 |
| Poster Presentation, 11B-Hydroxylase deficiency: a rare cause of endocrine hypertension in blacks, Pestola Conference 2012, Fort Worth, TX | 01/2012 |
| Poster Presentation, Hypocalcemia: a reversible cause of systolic heart failure, UMMC DOM and ACP Annual Abstract Day Competition, Jackson, MS - UMC | 10/2011 |
| Poster Presentation, Non-uremic Calciphylaxis: Rare disease, common outcome, UMMC DOM and ACP Annual Abstract Day Competition, Jackson, MS UMC | 10/2011 |
| Poster Presentation, Normal alkaline phosphatase in active Paget's disease of bone, UMMC DOM and ACP Annual Abstract Day Competition, Jackson, MS - UMC | 10/2011 |
| Poster Presentation, Calcidiol and Calcitriol Ameliorate Statin-Induced Myopathy in C2C12 Myotubules, The Endocrine Society - Endo 2011, Boston, Massachusetts | 06/2011 |
| Poster Presentation, Severely Decreased Bone Density in Graves Disease, The Endocrine Society - Endo 2011, Boston, Massachusetts | 06/2011 |
| Abstract, Modulation of expression of RA-regulated genes by the oncoprotein v-erbA, Annual Meeting of the Endocrine Society, San Francisco, CA | 06/2008 |
| Abstract, Characterization of the interacting domain of the cardiac myosin binding protein-c (cMBP-c) with the human mineralocorticoid receptor (hMR), Annual Meeting of the Endocrine Society | 06/2007 |
| Abstract, Thyroid hormone responsive genes in the murine hepatocyte cell line AML12, Annual meeting of the Endocrine Society | 06/2007 |
| State/Local Invited Seminars/Lectures, Disorders of HDL Metabolism, Medicine Grand Rounds, Jackson, MS | 2007 |
| State/Local Invited Seminars/Lectures, Multiple Endocrine Neoplasia (MEN), Medicine Grand Rounds, Jackson, MS | 2003 |
| State/Local Invited Seminars/Lectures, Primary Hyperparathyroidism, Medicine Grand Rounds, Jackson, MS | 2001 |
| State/Local Invited Seminars/Lectures, Type 2 Diabetes Mellitus Update, Nurse Practitioners, Jackson, MS | 09/2000 |
| Abstract presentation, Dimerization interfaces of v-erbA homodimers and heterodimers with RXR, 82nd Annual Meeting of the Endocrine Society, Toronto, Canada | 06/2000 |
| State/Local Invited Seminars/Lectures, Gene regulation by the ErbA superfamily, Division of Endocrinology and Metabolism Research Conference, Jackson, MS | 02/1997 |
| Abstract, V-erbA: DNA binding specificity and function, 10th International Endocrine Meeting of the Endocrine Society, San Francisco, CA | 06/1996 |
| State/Local Invited Seminars/Lectures, V-erbA: DNA binding specificity and function, Division of Endocrinology and Metabolism Research Conference, Jackson, MS | 05/1996 |
| State/Local Invited Seminars/Lectures, Diabetes Mellitus-The State of the Art: Hypoglycemia in patients with Diabetes Mellitus, VAMC, Jackson, MS | 03/1996 |
| State/Local Invited Seminars/Lectures, The Endocrine Paraneoplastic Syndromes, Medicine Grand Rounds, Jackson, MS | 1996 |
| State/Local Invited Seminars/Lectures, Diagnosis and Management of Hyperthryoidism, CME, Jackson, MS | 09/1995 |
| Abstract, DNA binding of retinoid X receptor homodimer, 77th Annual Meeting of the Endocrine Society, Washington, DC | 06/1995 |
| State/Local Invited Seminars/Lectures, The Endocrine Paraneoplastic Syndromes, Clinical Conferences, Jackson, MS | 03/1994 |
| Abstract, Identification of DNA sequences which bind v-erbA and RXR x, 75th Annual Meeting of the Endocrine Society, Las Vegas, Nevada | 06/1993 |
| State/Local Invited Seminars/Lectures, Identification of DNA sequences which bind V-erbA and RXRx, Division of Endocrinology and Metabolism Research Conference, Jackson, MS | 02/1993 |
| State/Local Invited Seminars/Lectures, Potential mutations in the DNA binding domain of C-erbAx2 that would transform it into an oncoprotein, Division of Endocrinology and Metabolism Research Conference, Jackson, MS | 12/1992 |
| Endocrinology Board Review (ESAP), ESAP review for fellows, Division of Endocrinology, Diabetes and Metabolism, Jackson, MS | |
| Lectures to third year medical students, Hypercalcemia and Thyroid Disorders, School of Medicine, Jackson, MS | |
| Lectures to second year medical students, Hyperthyroidism, School of Medicine | |
| Clinical Resident Conferences, Hyperthyroidism, hypothyroidism, hirsutism, gynecomastia, hypogonadism, hypercalcemia, hypocalcemia, lipid disorders, Medicine, UMMC, Jackson, MS | |
| State/Local Invited Seminars/Lectures, Introduction to Clinical Medicine Preceptor, School of Medicine, Jackson, MS | |
| Lectures to first year Medical Students, Thyroid Disorders, Diabetes Mellitus, Hypercalcemia, Lipid Disorders, Biochemistry, Physiology, Jackson, MS |
Honors, Awards, and Recognition
| M4 All Star Attending of the Year, Department of Medicine | 2011 |
| Teacher of the Year, University Mississippi Medical Center | 2011 |
| Norman C Nelson Order, University Mississipi Medical Center-Academic Office | 2010 |
| Excellence in Teaching Award, Dept of Medicine, UMMC | 2000 |
| Faculty Teacher of the Year Award, University of Mississippi Medical Center | |
| ALL-STAR Teaching Award, University of Mississippi Medical Center | |
| Evers Society Award - M3 All-star attending, University of Mississippi Medical Center | |
| ALL-STAR Teaching Award, Dept of Medicine, UMMC | |
| Young Faculty Award, SSCI-AFMR |
Professional Membership and Service
| Endocrine Society, Member | 2000 - Present |
| American College of Physicians, Member | 1993 - Present |
| Educational Committee, VAMC, Member, VAMC | |
| R & D Committee, VAMC, Member, VAMC | |
| Alpha Omega Alpha Honor Medical Society, House-staff member, Southern Illinois University | 1990 |
Committee Service
| Houseoffice Selection Committee, Member | 2012 - 2013 |
| DOM Research Council-subcommittee Basic Science, Member | 2011 - 2012 |
| Department of Medicine Houseoffice Selection Committee, Member | |
| Research Council, Member |
Teaching Experience
| Medicine, Lecture, Lecturer, Clinical Conference - M1 Lectures | |
| Medicine, Lecture, Lecturer, Clinical Conference - M2 Lectures | |
| Medicine, Lecture, Lecturer, Clinical Resident Conferences | |
| Graduate, Lecture, Lecturer, Core Lectures for Fellows | |
| Medicine, Consultant, Endocrinology and Metabolism Consultation Service | |
| Graduate, Small Group, Faculty, Endocrinology Board Review (ESAP) | |
| Medicine, Small Group, Faculty, Inpatient Medical Service | |
| Graduate, Small Group, Faculty, Journal Club | |
| 631, Medicine, Lecture, Lecturer, Medicine Clerkship | |
| 633, Medicine, Course, Course Director, Clinical Endocrinology | Spring 2013 |
| 666, Medicine, Course, Course Director, Endocrinology | Spring 2013 |
| 621, Medicine, Course, Preceptor, Introduction to Clinical Medicine | Spring 2013 |
| 621, Medicine, Course, Preceptor, Introduction to Clinical Medicine | Spring 2013 |
| 633, Medicine, Course, Course Director, Clinical Endocrinology | Fall 2012 |
| 666, Medicine, Course, Course Director, Endocrinology | Fall 2012 |
| 621, Medicine, Course, Preceptor, Introduction to Clinical Medicine | Fall 2012 |
| 633, Medicine, Course, Course Director, Clinical Endocrinology | Spring 2012 |
| 666, Medicine, Course, Course Director, Endocrinology | Spring 2012 |
| 633, Medicine, Course, Course Director, Clinical Endocrinology | Fall 2011 |
| 666, Medicine, Course, Course Director, Endocrinology | Fall 2011 |
| 633, Medicine, Course, Course Director, Clinical Endocrinology | Spring 2011 |
| 666, Medicine, Course, Course Director, Endocrinology | Spring 2011 |
| 633, Medicine, Course, Course Director, Clinical Endocrinology | Fall 2010 |
| 633, Medicine, Course, Course Director, Clinical Endocrinology | Fall 2010 |
| 666, Medicine, Course, Course Director, Endocrinology | Fall 2010 |
| Medicine, Lecture, Guest Presenter, Resident Noon Conference | Fall 2009 |
| Medicine, Lecture, Lecturer, Medicine Grand Rounds | 2007 |
| Medicine, Lecture, Lecturer, Medicine Grand Rounds | 2003 |
| Medicine, Lecture, Lecturer, Medicine Grand Rounds | 2001 |
| Nursing, Lecture, Guest Presenter, Clinical Conference - Nurse Practitioner Update | Fall 2000 |
| Medicine, Lecture, Lecturer, Research Conference - Division of Endocrinology and Metabolism | Winter 1997 |
| Medicine, Lecture, Lecturer, Medicine Grand Rounds | 1996 |
| Medicine, Lecture, Guest Presenter, Clinical Conference - Diabetes Mellitus - The State of the Art (VAMC) | Spring 1996 |
| Medicine, Lecture, Lecturer, Research Conference - Division of Endocrinology and Metabolism | Spring 1996 |
| Medicine, Lecture, Lecturer, Clinical Conference - Diagnosis and Management of Hyperthyroidism | Fall 1995 |
| Medicine, Lecture, Lecturer, Clinical Conference - The Endocrine Paraneoplastic Syndromes | Spring 1994 |
| Medicine, Lecture, Lecturer, Research Conference - Division of Endocrinology and Metabolism | Winter 1993 |
| Medicine, Lecture, Lecturer, Research Conference-Division of Endocrinology and Metabolism | Winter 1992 |
Directed Student Learning
| Supervised Research, Advised: Qing Shen, Inna Zubkova, Shema Ahmad |
Fellows supervised
| Endocrinology Fellowship Program, Program Director, 4 fellows supervised, Jana Phillips, Urseline Hawkins, Lane Frey, Timothy Moran | 07/2012 - 06/2013 |
| Endocrinology Fellowship Program, Attending Physician, 5 fellows supervised, VA Endocrine Clinic-Honey East, Nuttha Ungnapatanin, Sarah French, Urseline Hawkins, Jana Phillips | 07/2011 - 06/2012 |
| Endocrinology Fellowship Program, Attending Physician, 4 fellows supervised, VA Lipid Clinic - Sarah French, Urseline Hawkins, Nuttha Ungnapatanin, Jana Phillips | 07/2011 - 06/2012 |
| Endocrine Fellowship Program, Program Director, 5 fellows supervised, VA Endocrine Clinic-Anthony Gannon, Niyutchai Chaithongdi, Sarah French, Honey East, Nuttha Ungnapatanin | 07/2010 - 06/2011 |
| Endocrinology Fellowship Program, Program Director, 4 fellows supervised, VA Lipid Clinic - Niyutchai Chaithongdi, Anthony Gannon, Sarah French, Nuttha Ungnapatanin | 07/2010 - 06/2011 |
| Endocrinology-Laboratory, Training Faculty, 1 fellows supervised, Anthony Gannon | 01/2009 - 01/2011 |
| Endocrinology Fellowship Program, Program Director, 5 fellows supervised | 01/2003 - Present |