Journal Article |
| Sharma A, Vikramdeo KS, Sudan SK, Anand S, Deshmukh SK, Singh AP, Singh S, Cortisol affects macrophage polarization by inducing miR-143/145 cluster to reprogram glucose metabolism and by promoting TCA cycle anaplerosis. The Journal of biological chemistry, 2024 Oct;300(10):107753 | 2024 |
| Sudan SK, Sharma A, Vikramdeo KS, Davis W, Deshmukh SK, Poosarla T, Holliday NP, Prodduturvar P, Nelson C, Singh KP, Singh AP, Singh S, Obesity and Early-Onset Breast Cancer and Specific Molecular Subtype Diagnosis in Black and White Women: NIMHD Social Epigenomics Program. JAMA network open, 2024 Jul 1;7(7):e2421846 | 2024 |
| Anand S, Vikramdeo KS, Sudan SK, Sharma A, Acharya S, Khan MA, Singh S, Singh AP, From modulation of cellular plasticity to potentiation of therapeutic resistance: new and emerging roles of MYB transcription factors in human malignancies. Cancer metastasis reviews, 2024 Mar;43(1):409-421 | 2024 |
| Haastrup MO, Vikramdeo KS, Anand S, Khan MA, Carter JE, Singh S, Singh AP, Dasgupta S, Mitochondrial Translocase TOMM22 Is Overexpressed in Pancreatic Cancer and Promotes Aggressive Growth by Modulating Mitochondrial Protein Import and Function. Molecular cancer research : MCR, 2024 Feb 1;22(2):197-208 | 2024 |
| Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ, MISEV Consortium, Théry C, Witwer KW, Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of extracellular vesicles, 2024 Feb;13(2):e12404 | 2024 |
| Khan MA, Acharya S, Anand S, Sameeta F, Pramanik P, Keel C, Singh S, Carter JE, Dasgupta S, Singh AP, MYB exhibits racially disparate expression, clinicopathologic association, and predictive potential for biochemical recurrence in prostate cancer. iScience, 2023 Dec 15;26(12):108487 | 2023 |
| Vikramdeo KS, Anand S, Sudan SK, Pramanik P, Singh S, Godwin AK, Singh AP, Dasgupta S, Profiling mitochondrial DNA mutations in tumors and circulating extracellular vesicles of triple-negative breast cancer patients for potential biomarker development. FASEB bioAdvances, 2023 Oct;5(10):412-426 | 2023 |
| Hertweck KL, Vikramdeo KS, Galeas JN, Marbut SM, Pramanik P, Yunus F, Singh S, Singh AP, Dasgupta S, Clinicopathological significance of unraveling mitochondrial pathway alterations in non-small-cell lung cancer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023 Jul;37(7):e23018 | 2023 |
| Kakkat S, Pramanik P, Singh S, Singh AP, Sarkar C, Chakroborty D, Cardiovascular Complications in Patients with Prostate Cancer: Potential Molecular Connections. International journal of molecular sciences, 2023 Apr 10;24(8) | 2023 |
| Vikramdeo KS, Sharma A, Anand S, Sudan SK, Singh S, Singh AP, Dasgupta S, Mitochondrial Alterations in Prostate Cancer: Roles in Pathobiology and Racial Disparities. International journal of molecular sciences, 2023 Feb 24;24(5) | 2023 |
| Haastrup MO, Vikramdeo KS, Singh S, Singh AP, Dasgupta S, The Journey of Mitochondrial Protein Import and the Roadmap to Follow. International journal of molecular sciences, 2023 Jan 27;24(3) | 2023 |
| Anand S, Khan MA, Zubair H, Sudan SK, Vikramdeo KS, Deshmukh SK, Azim S, Srivastava SK, Singh S, Singh AP, MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming. EMBO reports, 2023 Mar 6;24(3):e55643 | 2023 |
| Acharya S, Anand S, Khan MA, Zubair H, Srivastava SK, Singh S, Singh AP, Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer. The Journal of biological chemistry, 2023 Jan;299(1):102725 | 2023 |
| Vikramdeo KS, Anand S, Khan MA, Khushman M, Heslin MJ, Singh S, Singh AP, Dasgupta S, Detection of mitochondrial DNA mutations in circulating mitochondria-originated extracellular vesicles for potential diagnostic applications in pancreatic adenocarcinoma. Scientific reports, 2022 Nov 2;12(1):18455 | 2022 |
| Vikramdeo KS, Anand S, Pierce JY, Singh AP, Singh S, Dasgupta S, Distribution of microbiota in cervical preneoplasia of racially disparate populations. BMC cancer, 2022 Oct 18;22(1):1074 | 2022 |
| Vikramdeo KS, Sudan SK, Singh AP, Singh S, Dasgupta S, Mitochondrial respiratory complexes: Significance in human mitochondrial disorders and cancers. Journal of cellular physiology, 2022 Nov;237(11):4049-4078 | 2022 |
| Nguyen A, Battle K, Paudel SS, Xu N, Bell J, Ayers L, Chapman C, Singh AP, Palanki S, Rich T, Alvarez DF, Stevens T, Tambe DT, Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence. Journal of visualized experiments : JoVE, 2022 Mar 5;(181) | 2022 |
| Srivastava SK, Khan MA, Anand S, Zubair H, Deshmukh SK, Patel GK, Singh S, Andrews J, Wang B, Carter JE, Singh AP, MYB interacts with androgen receptor, sustains its ligand-independent activation and promotes castration resistance in prostate cancer. British journal of cancer, 2022 May;126(8):1205-1214 | 2022 |
| Saranyutanon S, Acharya S, Deshmukh SK, Khan MA, Singh S, Singh AP, Nicotine causes alternative polarization of macrophages via Src-mediated STAT3 activation: Potential pathobiological implications. Journal of cellular physiology, 2022 Feb;237(2):1486-1497 | 2022 |
| Zubair H, Khan MA, Anand S, Srivastava SK, Singh S, Singh AP, Modulation of the tumor microenvironment by natural agents: implications for cancer prevention and therapy. Seminars in cancer biology, 2022 May;80:237-255 | 2022 |
| Deshmukh SK, Srivastava SK, Zubair H, Khan MA, Singh AP, Singh S, Resistin Induces LIN28A-Mediated Let-7a Repression in Breast Cancer Cells Leading to IL-6 and STAT3 Upregulation. Cancers, 2021 Sep 7;13(18) | 2021 |
| Khan MA, Vikramdeo KS, Sudan SK, Singh S, Wilhite A, Dasgupta S, Rocconi RP, Singh AP, Platinum-resistant ovarian cancer: From drug resistance mechanisms to liquid biopsy-based biomarkers for disease management. Seminars in cancer biology, 2021 Dec;77:99-109 | 2021 |
| Khushman M, Prodduturvar P, Mneimneh W, Zotto VD, Akbar S, Grimm L, Rider P, Hunter J, Alkharabsheh O, Patel GK, Fabregas JC, Singh AP, The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma. Oncotarget, 2021 Jul 20;12(15):1490-1498 | 2021 |
| Miree O, Srivastava SK, Khan MA, Sameeta F, Acharya S, Ndetan H, Singh KP, Hertweck KL, Dasgupta S, da Silva LM, Rocconi RP, Carter JE, Singh S, Singh AP, Clinicopathologic significance and race-specific prognostic association of MYB overexpression in ovarian cancer. Scientific reports, 2021 Jun 18;11(1):12901 | 2021 |
| Adebayo M, Singh S, Singh AP, Dasgupta S, Mitochondrial fusion and fission: The fine-tune balance for cellular homeostasis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021 Jun;35(6):e21620 | 2021 |
| Khushman M, Patel GK, Maharjan AS, McMillin GA, Nelson C, Hosein P, Singh AP, The prevalence and clinical relevance of 2R/2R TYMS genotype in patients with gastrointestinal malignancies treated with fluoropyrimidine-based chemotherapy regimens. The pharmacogenomics journal, 2021 Jun;21(3):308-317 | 2021 |
| Deshmukh SK, Khan MA, Singh S, Singh AP, Extracellular Nanovesicles: From Intercellular Messengers to Efficient Drug Delivery Systems. ACS omega, 2021 Jan 26;6(3):1773-1779 | 2021 |
| Saranyutanon S, Deshmukh SK, Dasgupta S, Pai S, Singh S, Singh AP, Cellular and Molecular Progression of Prostate Cancer: Models for Basic and Preclinical Research. Cancers, 2020 Sep 17;12(9) | 2020 |
| Kanchanapally R, Khan MA, Deshmukh SK, Srivastava SK, Khushman M, Singh S, Singh AP, Exosomal Formulation Escalates Cellular Uptake of Honokiol Leading to the Enhancement of Its Antitumor Efficacy. ACS omega, 2020 Sep 15;5(36):23299-23307 | 2020 |
| Sudan SK, Deshmukh SK, Poosarla T, Holliday NP, Dyess DL, Singh AP, Singh S, Resistin: An inflammatory cytokine with multi-faceted roles in cancer. Biochimica et biophysica acta. Reviews on cancer, 2020 Dec;1874(2):188419 | 2020 |
| Anand S, Khan MA, Khushman M, Dasgupta S, Singh S, Singh AP, Comprehensive Analysis of Expression, Clinicopathological Association and Potential Prognostic Significance of RABs in Pancreatic Cancer. International journal of molecular sciences, 2020 Aug 4;21(15) | 2020 |
| Khan MA, Srivastava SK, Zubair H, Patel GK, Arora S, Khushman M, Carter JE, Gorman GS, Singh S, Singh AP, Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer. The Journal of biological chemistry, 2020 Jun 19;295(25):8413-8424 | 2020 |
| Zubair H, Patel GK, Khan MA, Azim S, Zubair A, Singh S, Srivastava SK, Singh AP, Proteomic Analysis of MYB-Regulated Secretome Identifies Functional Pathways and Biomarkers: Potential Pathobiological and Clinical Implications. Journal of proteome research, 2020 Feb 7;19(2):794-804 | 2020 |
| Khan MA, Zubair H, Anand S, Srivastava SK, Singh S, Singh AP, Dysregulation of metabolic enzymes in tumor and stromal cells: Role in oncogenesis and therapeutic opportunities. Cancer letters, 2020 Mar 31;473:176-185 | 2020 |
| Patton MC, Zubair H, Khan MA, Singh S, Singh AP, Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival. Journal of cellular biochemistry, 2020 Jan;121(1):828-839 | 2020 |
| Saranyutanon S, Srivastava SK, Pai S, Singh S, Singh AP, Therapies Targeted to Androgen Receptor Signaling Axis in Prostate Cancer: Progress, Challenges, and Hope. Cancers, 2019 Dec 23;12(1) | 2019 |
| Deshmukh SK, Srivastava SK, Poosarla T, Dyess DL, Holliday NP, Singh AP, Singh S, Inflammation, immunosuppressive microenvironment and breast cancer: opportunities for cancer prevention and therapy. Annals of translational medicine, 2019 Oct;7(20):593 | 2019 |
| Patel GK, Khan MA, Zubair H, Srivastava SK, Khushman M, Singh S, Singh AP, Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications. Scientific reports, 2019 Mar 29;9(1):5335 | 2019 |
| Khushman M, Patel GK, Laurini JA, Bhardwaj A, Roveda K, Donnell R, Sherling K, Case B, Frankel AE, Pai S, Taylor W, Tan MCB, Mizrahi M, Nelson C, Wyatt M, Patton M, McClellan S, Singh S, Wang B, Singh AP, Exosomal markers (CD63 and CD9) expression and their prognostic significance using immunohistochemistry in patients with pancreatic ductal adenocarcinoma. Journal of gastrointestinal oncology, 2019 Aug;10(4):695-702 | 2019 |
| Chavva SR, Deshmukh SK, Kanchanapally R, Tyagi N, Coym JW, Singh AP, Singh S, Epigallocatechin Gallate-Gold Nanoparticles Exhibit Superior Antitumor Activity Compared to Conventional Gold Nanoparticles: Potential Synergistic Interactions. Nanomaterials (Basel, Switzerland), 2019 Mar 8;9(3) | 2019 |
| Maharjan AS, McMillin GA, Patel GK, Awan S, Taylor WR, Pai S, Frankel AE, Nelson C, Wang B, Hosein PJ, Singh AP, Khushman M, The Prevalence of DPYD*9A(c.85T>C) Genotype and the Genotype-Phenotype Correlation in Patients with Gastrointestinal Malignancies Treated With Fluoropyrimidines: Updated Analysis. Clinical colorectal cancer, 2019 Sep;18(3):e280-e286 | 2019 |
| Deshmukh SK, Tyagi N, Khan MA, Srivastava SK, Al-Ghadhban A, Dugger K, Carter JE, Singh S, Singh AP, Gemcitabine treatment promotes immunosuppressive microenvironment in pancreatic tumors by supporting the infiltration, growth, and polarization of macrophages. Scientific reports, 2018 Aug 10;8(1):12000 | 2018 |
| Tyagi N, Deshmukh SK, Srivastava SK, Azim S, Ahmad A, Al-Ghadhban A, Singh AP, Carter JE, Wang B, Singh S, ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1. Molecular cancer research : MCR, 2018 Feb;16(2):187-196 | 2018 |
| Deshmukh SK, Singh AP, Singh S, ETV4: an emerging target in pancreatic cancer. Oncoscience, 2018 Sep;5(9-10):260-261 | 2018 |
| Khushman M, Patel GK, Hosein PJ, Laurini JA, Cameron D, Clarkson DR, Butler TW, Norden CW, Baliem W, Jones V, Bhadkamkar S, Nelson C, Lee F, Singh AP, Taylor WR, Germline pharmacogenomics of DPYD*9A (c.85T>C) variant in patients with gastrointestinal malignancies treated with fluoropyrimidines. Journal of gastrointestinal oncology, 2018 Jun;9(3):416-424 | 2018 |
| Srivastava SK, Ahmad A, Zubair H, Miree O, Singh S, Rocconi RP, Scalici J, Singh AP, MicroRNAs in gynecological cancers: Small molecules with big implications. Cancer letters, 2017 Oct 28;407:123-138 | 2017 |
| Khan MA, Azim S, Zubair H, Bhardwaj A, Patel GK, Khushman M, Singh S, Singh AP, Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward. International journal of molecular sciences, 2017 Apr 6;18(4) | 2017 |
| Deshmukh SK, Srivastava SK, Zubair H, Bhardwaj A, Tyagi N, Al-Ghadhban A, Singh AP, Dyess DL, Carter JE, Singh S, Resistin potentiates chemoresistance and stemness of breast cancer cells: Implications for racially disparate therapeutic outcomes. Cancer letters, 2017 Jun 28;396:21-29 | 2017 |
| Zubair H, Azim S, Ahmad A, Khan MA, Patel GK, Singh S, Singh AP, Cancer Chemoprevention by Phytochemicals: Nature's Healing Touch. Molecules (Basel, Switzerland), 2017 Mar 3;22(3) | 2017 |
| Patel GK, Khan MA, Bhardwaj A, Srivastava SK, Zubair H, Patton MC, Singh S, Khushman M, Singh AP, Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK. British journal of cancer, 2017 Feb 28;116(5):609-619 | 2017 |
| Ahmad A, Azim S, Zubair H, Khan MA, Singh S, Carter JE, Rocconi RP, Singh AP, Epigenetic basis of cancer health disparities: Looking beyond genetic differences. Biochimica et biophysica acta. Reviews on cancer, 2017 Aug;1868(1):16-28 | 2017 |
| Srivastava SK, Ahmad A, Miree O, Patel GK, Singh S, Rocconi RP, Singh AP, Racial health disparities in ovarian cancer: not just black and white. Journal of ovarian research, 2017 Sep 21;10(1):58 | 2017 |
| Deshmukh SK, Srivastava SK, Tyagi N, Ahmad A, Singh AP, Ghadhban AAL, Dyess DL, Carter JE, Dugger K, Singh S, Emerging evidence for the role of differential tumor microenvironment in breast cancer racial disparity: a closer look at the surroundings. Carcinogenesis, 2017 Aug 1;38(8):757-765 | 2017 |
| Bhardwaj A, Srivastava SK, Khan MA, Prajapati VK, Singh S, Carter JE, Singh AP, Racial disparities in prostate cancer: a molecular perspective. Frontiers in bioscience (Landmark edition), 2017 Jan 1;22(5):772-782 | 2017 |
| Zubair H, Azim S, Srivastava SK, Ahmad A, Bhardwaj A, Khan MA, Patel GK, Arora S, Carter JE, Singh S, Singh AP, Glucose Metabolism Reprogrammed by Overexpression of IKKε Promotes Pancreatic Tumor Growth. Cancer research, 2016 Dec 15;76(24):7254-7264 | 2016 |
| Azim S, Zubair H, Srivastava SK, Bhardwaj A, Zubair A, Ahmad A, Singh S, Khushman M, Singh AP, Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer. Scientific reports, 2016 Jun 29;6:28446 | 2016 |
| Zubair H, Azim S, Khan HY, Ullah MF, Wu D, Singh AP, Hadi SM, Ahmad A, Mobilization of Intracellular Copper by Gossypol and Apogossypolone Leads to Reactive Oxygen Species-Mediated Cell Death: Putative Anticancer Mechanism. International journal of molecular sciences, 2016 Jun 20;17(5) | 2016 |
| Tyagi N, Srivastava SK, Arora S, Omar Y, Ijaz ZM, Al-Ghadhban A, Deshmukh SK, Carter JE, Singh AP, Singh S, Comparative analysis of the relative potential of silver, Zinc-oxide and titanium-dioxide nanoparticles against UVB-induced DNA damage for the prevention of skin carcinogenesis. Cancer letters, 2016 Dec 1;383(1):53-61 | 2016 |
| Averett C, Bhardwaj A, Arora S, Srivastava SK, Khan MA, Ahmad A, Singh S, Carter JE, Khushman M, Singh AP, Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk. Carcinogenesis, 2016 Nov 1;37(11):1052-1061 | 2016 |
| Bhardwaj A, Srivastava SK, Singh S, Tyagi N, Arora S, Carter JE, Khushman M, Singh AP, MYB Promotes Desmoplasia in Pancreatic Cancer through Direct Transcriptional Up-regulation and Cooperative Action of Sonic Hedgehog and Adrenomedullin. The Journal of biological chemistry, 2016 Jul 29;291(31):16263-70 | 2016 |
| Tyagi N, Marimuthu S, Bhardwaj A, Deshmukh SK, Srivastava SK, Singh AP, McClellan S, Carter JE, Singh S, p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling. Cancer letters, 2016 Jan 28;370(2):260-7 | 2016 |
| Tyagi N, Arora S, Deshmukh SK, Singh S, Marimuthu S, Singh AP, Exploiting Nanotechnology for the Development of MicroRNA-Based Cancer Therapeutics. Journal of biomedical nanotechnology, 2016 Jan;12(1):28-42 | 2016 |
| Khan MA, Srivastava SK, Bhardwaj A, Singh S, Arora S, Zubair H, Carter JE, Singh AP, Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications. Oncotarget, 2015 Nov 17;6(36):39140-50 | 2015 |
| Srivastava SK, Bhardwaj A, Arora S, Singh S, Azim S, Tyagi N, Carter JE, Wang B, Singh AP, MYB is a novel regulator of pancreatic tumour growth and metastasis. British journal of cancer, 2015 Dec 22;113(12):1694-703 | 2015 |
| Tyagi N, Bhardwaj A, Srivastava SK, Arora S, Marimuthu S, Deshmukh SK, Singh AP, Carter JE, Singh S, Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis. Scientific reports, 2015 Sep 9;5:13894 | 2015 |
| Srivastava SK, Bhardwaj A, Arora S, Tyagi N, Singh S, Andrews J, McClellan S, Wang B, Singh AP, MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways. British journal of cancer, 2015 Aug 11;113(4):660-8 | 2015 |
| Srivastava SK, Bhardwaj A, Arora S, Tyagi N, Singh AP, Carter JE, Scammell JG, Fodstad Ø, Singh S, Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis. British journal of cancer, 2015 May 26;112(11):1772-81 | 2015 |
| Deshmukh SK, Srivastava SK, Bhardwaj A, Singh AP, Tyagi N, Marimuthu S, Dyess DL, Dal Zotto V, Carter JE, Singh S, Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation. Oncotarget, 2015 May 10;6(13):11231-41 | 2015 |
| Palanki R, Arora S, Tyagi N, Rusu L, Singh AP, Palanki S, Carter JE, Singh S, Size is an essential parameter in governing the UVB-protective efficacy of silver nanoparticles in human keratinocytes. BMC cancer, 2015 Sep 15;15:636 | 2015 |
| Arora S, Tyagi N, Bhardwaj A, Rusu L, Palanki R, Vig K, Singh SR, Singh AP, Palanki S, Miller ME, Carter JE, Singh S, Silver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis. Nanomedicine : nanotechnology, biology, and medicine, 2015 Jul;11(5):1265-75 | 2015 |
| Bhardwaj A, Srivastava SK, Singh S, Arora S, Tyagi N, Andrews J, McClellan S, Carter JE, Singh AP, CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1. Oncotarget, 2014 Nov 30;5(22):11490-500 | 2014 |
| Bhardwaj A, Singh S, Srivastava SK, Arora S, Hyde SJ, Andrews J, Grizzle WE, Singh AP, Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model. British journal of cancer, 2014 Apr 15;110(8):2000-10 | 2014 |
| Srivastava SK, Arora S, Singh S, Bhardwaj A, Averett C, Singh AP, MicroRNAs in pancreatic malignancy: progress and promises. Cancer letters, 2014 Jun 1;347(2):167-74 | 2014 |
| Tyagi N, Bhardwaj A, Singh AP, McClellan S, Carter JE, Singh S, p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway. Oncotarget, 2014 Sep 30;5(18):8778-89 | 2014 |
| Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Nirodi CS, Piazza GA, Grizzle WE, Owen LB, Singh AP, An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4. The Journal of biological chemistry, 2013 Jul 19;288(29):21197-21207 | 2013 |
| Srivastava SK, Bhardwaj A, Leavesley SJ, Grizzle WE, Singh S, Singh AP, MicroRNAs as potential clinical biomarkers: emerging approaches for their detection. Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2013 Oct;88(7):373-87 | 2013 |
| Bhardwaj A, Arora S, Prajapati VK, Singh S, Singh AP, Cancer "stemness"- regulating microRNAs: role, mechanisms and therapeutic potential. Current drug targets, 2013 Sep;14(10):1175-84 | 2013 |
| Singh AP, Arora S, Bhardwaj A, Srivastava SK, Kadakia MP, Wang B, Grizzle WE, Owen LB, Singh S, CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions. The Journal of biological chemistry, 2012 Nov 9;287(46):39115-24 | 2012 |
| Srivastava SK, Bhardwaj A, Singh S, Arora S, McClellan S, Grizzle WE, Reed E, Singh AP, Myb overexpression overrides androgen depletion-induced cell cycle arrest and apoptosis in prostate cancer cells, and confers aggressive malignant traits: potential role in castration resistance. Carcinogenesis, 2012 Jun;33(6):1149-57 | 2012 |
| Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP, Honokiol: a novel natural agent for cancer prevention and therapy. Current molecular medicine, 2012 Dec;12(10):1244-52 | 2012 |
| Srivastava SK, Bhardwaj A, Singh S, Arora S, Wang B, Grizzle WE, Singh AP, MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. Carcinogenesis, 2011 Dec;32(12):1832-9 | 2011 |
| Bhardwaj A, Singh S, Srivastava SK, Honkanen RE, Reed E, Singh AP, Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implications. Molecular cancer therapeutics, 2011 May;10(5):720-31 | 2011 |
| Singh S, Srivastava SK, Bhardwaj A, Owen LB, Singh AP, CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy. British journal of cancer, 2010 Nov 23;103(11):1671-9 | 2010 |
| Singh S, Singh AP, Sharma B, Owen LB, Singh RK, CXCL8 and its cognate receptors in melanoma progression and metastasis. Future oncology (London, England), 2010 Jan;6(1):111-6 | 2010 |
| Singh AP, Senapati S, Ponnusamy MP, Jain M, Lele SM, Davis JS, Remmenga S, Batra SK, Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer. The Lancet. Oncology, 2008 Nov;9(11):1076-85 | 2008 |
| Bafna S, Singh AP, Moniaux N, Eudy JD, Meza JL, Batra SK, MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells. Cancer research, 2008 Nov 15;68(22):9231-8 | 2008 |
| Ponnusamy MP, Singh AP, Jain M, Chakraborty S, Moniaux N, Batra SK, MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells. British journal of cancer, 2008 Aug 5;99(3):520-6 | 2008 |
| Chaturvedi P, Singh AP, Chakraborty S, Chauhan SC, Bafna S, Meza JL, Singh PK, Hollingsworth MA, Mehta PP, Batra SK, MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells. Cancer research, 2008 Apr 1;68(7):2065-70 | 2008 |
| Chaturvedi P, Singh AP, Batra SK, Structure, evolution, and biology of the MUC4 mucin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008 Apr;22(4):966-81 | 2008 |
| Singh AP, Bafna S, Chaudhary K, Venkatraman G, Smith L, Eudy JD, Johansson SL, Lin MF, Batra SK, Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells. Cancer letters, 2008 Jan 18;259(1):28-38 | 2008 |
| Andrianifahanana M, Singh AP, Nemos C, Ponnusamy MP, Moniaux N, Mehta PP, Varshney GC, Batra SK, IFN-gamma-induced expression of MUC4 in pancreatic cancer cells is mediated by STAT-1 upregulation: a novel mechanism for IFN-gamma response. Oncogene, 2007 Nov 8;26(51):7251-61 | 2007 |
| Chaturvedi P, Singh AP, Moniaux N, Senapati S, Chakraborty S, Meza JL, Batra SK, MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins. Molecular cancer research : MCR, 2007 Apr;5(4):309-20 | 2007 |
| Singh AP, Chaturvedi P, Batra SK, Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy. Cancer research, 2007 Jan 15;67(2):433-6 | 2007 |
| Chen SJ, Karan D, Johansson SL, Lin FF, Zeckser J, Singh AP, Batra SK, Lin MF, Prostate-derived factor as a paracrine and autocrine factor for the proliferation of androgen receptor-positive human prostate cancer cells. The Prostate, 2007 Apr 1;67(5):557-71 | 2007 |
| Ponnusamy MP, Venkatraman G, Singh AP, Chauhan SC, Johansson SL, Jain M, Smith L, Davis JS, Remmenga SW, Batra SK, Expression of TAG-72 in ovarian cancer and its correlation with tumor stage and patient prognosis. Cancer letters, 2007 Jun 28;251(2):247-57 | 2007 |
| Singh AP, Chauhan SC, Andrianifahanana M, Moniaux N, Meza JL, Copin MC, van Seuningen I, Hollingsworth MA, Aubert JP, Batra SK, MUC4 expression is regulated by cystic fibrosis transmembrane conductance regulator in pancreatic adenocarcinoma cells via transcriptional and post-translational mechanisms. Oncogene, 2007 Jan 4;26(1):30-41 | 2007 |
| Wittel UA, Singh AP, Henley BJ, Andrianifahanana M, Akhter MP, Cullen DM, Batra SK, Cigarette smoke-induced differential expression of the genes involved in exocrine function of the rat pancreas. Pancreas, 2006 Nov;33(4):364-70 | 2006 |
| Chauhan SC, Singh AP, Ruiz F, Johansson SL, Jain M, Smith LM, Moniaux N, Batra SK, Aberrant expression of MUC4 in ovarian carcinoma: diagnostic significance alone and in combination with MUC1 and MUC16 (CA125). Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2006 Oct;19(10):1386-94 | 2006 |
| Moniaux N, Junker WM, Singh AP, Jones AM, Batra SK, Characterization of human mucin MUC17. Complete coding sequence and organization. The Journal of biological chemistry, 2006 Aug 18;281(33):23676-85 | 2006 |
| Singh AP, Chauhan SC, Bafna S, Johansson SL, Smith LM, Moniaux N, Lin MF, Batra SK, Aberrant expression of transmembrane mucins, MUC1 and MUC4, in human prostate carcinomas. The Prostate, 2006 Mar 1;66(4):421-9 | 2006 |
| Jain M, Chauhan SC, Singh AP, Venkatraman G, Colcher D, Batra SK, Penetratin improves tumor retention of single-chain antibodies: a novel step toward optimization of radioimmunotherapy of solid tumors. Cancer research, 2005 Sep 1;65(17):7840-6 | 2005 |
| Andrianifahanana M, Agrawal A, Singh AP, Moniaux N, van Seuningen I, Aubert JP, Meza J, Batra SK, Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways. Oncogene, 2005 Sep 8;24(40):6143-54 | 2005 |
| Singh AP, Moniaux N, Chauhan SC, Meza JL, Batra SK, Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis. Cancer research, 2004 Jan 15;64(2):622-30 | 2004 |
| Karan D, Chen SJ, Johansson SL, Singh AP, Paralkar VM, Lin MF, Batra SK, Dysregulated expression of MIC-1/PDF in human prostate tumor cells. Biochemical and biophysical research communications, 2003 Jun 6;305(3):598-604 | 2003 |
| Anand S, Vikramdeo KS, Singh S, Singh AP, Dasgupta S, Racial disparities in the genetic landscape of lung cancer. Cancer health disparities, 2022;6 | |
| Goswami S, Sarkar C, Singh S, Singh AP, Chakroborty D, Racial differences in prostate tumor microenvironment: implications for disparate clinical outcomes and potential opportunities. Cancer health disparities, 2022;6 | |
| Brady KC, Stephens CP, Sudan SK, Singh AP, Dasgupta S, Singh S, Breast and Cervical cancer disparities in Alabama: current scenario, ongoing efforts to reduce the disparity gaps, and what more we could be doing. Cancer health disparities, 2022;6:e1-e10 | |
| Khan MA, Anand S, Deshmukh SK, Singh S, Singh AP, Determining the Size Distribution and Integrity of Extracellular Vesicles by Dynamic Light Scattering. Methods in molecular biology (Clifton, N.J.), 2022;2413:165-175 | |
| Miree O, Srivastava SK, Dasgupta S, Singh S, Rocconi R, Singh AP, Current and Futuristic Roadmap of Ovarian Cancer Management: An Overview. Advances in experimental medicine and biology, 2021;1330:1-19 | |
| Patel GK, Perry JB, Abdul-Rahim O, Frankel AE, Cameron D, Taylor W, Rocconi RP, Abushahin L, Nelson C, Singh AP, Khushman M, Epidermal growth factor receptor-activating mutation(E746_T751>VP) in pancreatic ductal adenocarcinoma responds to erlotinib, followed by epidermal growth factor receptor resistance-mediating mutation (A647T): A case report and literature review. Journal of cancer research and therapeutics, 2020 Jul-Sep;16(4):950-954 | |
| Zubair H, Bhardwaj A, Ahmad A, Srivastava SK, Khan MA, Patel GK, Singh S, Singh AP, Hydroxytyrosol Induces Apoptosis and Cell Cycle Arrest and Suppresses Multiple Oncogenic Signaling Pathways in Prostate Cancer Cells. Nutrition and cancer, 2017 Aug-Sep;69(6):932-942 | |
| Deshmukh SK, Azim S, Ahmad A, Zubair H, Tyagi N, Srivastava SK, Bhardwaj A, Singh S, Rocconi RP, Singh AP, Biological basis of cancer health disparities: resources and challenges for research. American journal of cancer research, 2017;7(1):1-12 | |
| Khan MA, Zubair H, Srivastava SK, Singh S, Singh AP, Insights into the Role of microRNAs in Pancreatic Cancer Pathogenesis: Potential for Diagnosis, Prognosis, and Therapy. Advances in experimental medicine and biology, 2015;889:71-87 | |
| Averett C, Arora S, Zubair H, Singh S, Bhardwaj A, Singh AP, Molecular Targets of Honokiol: A Promising Phytochemical for Effective Cancer Management. The Enzymes, 2014;36:175-93 | |
| Khan MA, Patel GK, Srivastava SK, Carter JE, Pierce JY, Rocconi RP, Singh S, Singh AP, Looking at cancer health disparities without the colored lenses. Cancer health disparities, 2019;3:e1-e9 | |
| Kanchanapally R, Deshmukh SK, Chavva SR, Tyagi N, Srivastava SK, Patel GK, Singh AP, Singh S, Drug-loaded exosomal preparations from different cell types exhibit distinctive loading capability, yield, and antitumor efficacies: a comparative analysis. International journal of nanomedicine, 2019;14:531-541 | |
| Srivastava SK, Arora S, Averett C, Singh S, Singh AP, Modulation of microRNAs by phytochemicals in cancer: underlying mechanisms and translational significance. BioMed research international, 2015;2015:848710 | |
| Arora S, Swaminathan SK, Kirtane A, Srivastava SK, Bhardwaj A, Singh S, Panyam J, Singh AP, Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy. International journal of nanomedicine, 2014;9:2933-42 | |
| Arora S, Bhardwaj A, Srivastava SK, Singh S, McClellan S, Wang B, Singh AP, Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells. PloS one, 2011;6(6):e21573 | |
| Bhardwaj A, Singh S, Singh AP, MicroRNA-based Cancer Therapeutics: Big Hope from Small RNAs. Molecular and cellular pharmacology, 2010;2(5):213-219 | |
| Patel GK, Taylor W, Singh S, Khushman M, Singh AP, Revisiting the Clinical Importance of DPYD*9A (c.85T>C) Variant of Dihydropyrimidine Dehydrogenase (DPYD) Gene in Patients Treated with Fluoropyrimidine-Based Chemotherapy. Journal of molecular biomarkers & diagnosis, 2018;9(3) | |
| Patel GK, Patton MC, Singh S, Khushman M, Singh AP, Pancreatic Cancer Exosomes: Shedding Off for a Meaningful Journey. Pancreatic disorders & therapy, 2016;6(2):e148 | |
Editorial |
| Chakroborty D, Singh AP, Prostate Cancer: Insights into Disease Progression and Therapeutic Challenges. International journal of molecular sciences, 2024 Feb 20;25(5) | 2024 |
| Singh S, Singh AP, Mitra R, Cancer-Associated Fibroblasts: Major Co-Conspirators in Tumor Development. Cancers, 2024 Jan 2;16(1) | 2024 |
| Sharma A, Singh AP, Singh S, Shaping Up the Tumor Microenvironment: Extracellular Vesicles as Important Intermediaries in Building a Tumor-Supportive Cellular Network. Cancers, 2023 Jan 13;15(2) | 2023 |
| Anand S, Khan MA, Singh AP, Turning Adversity into Strength and Transferring It to the Uninitiated: The Tricks Cancer Cells Play to Survive Hypoxic Stress and Fight Chemotherapy. Cancers, 2022 Dec 28;15(1) | 2022 |
| Singh S, Singh AP, Exosomes: Tools and targets for cancer diagnosis, prognosis, and therapy. Cancer letters, 2022 Oct 28;547:215865 | 2022 |
