Corbin A. Shields, PhD

Corbin A. Shields, PhD

Instructor

Department:
SOM-Pharmacology/Toxicology

Email:
cashields@umc.edu

Work Phone:
(601) 984-1697

Education

University of Mississippi Medical Center, PhD, Experimental Therapeutics and Pharmacology2021

Current Positions

Instructor, School of Medicine, Department of Pharmacology / Toxicology02/2023 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Publications

Journal Article

Poudel B, Ekperikpe US, Mandal S, Wilson GE, Shields CA, Cornelius DC, Williams JM, Chronic treatment with IL-25 increases renal M2 macrophages and reduces renal injury in obese Dahl salt-sensitive rats during the prepubescent stage. American journal of physiology. Renal physiology, 2023 Jul 1;325(1):F87-F982023
Wang X, Shields CA, Ekperikpe U, Amaral LM, Williams JM, Cornelius DC, VASCULAR AND RENAL MECHANISMS OF PREECLAMPSIA. Current opinion in physiology, 2023 Jun;332023
Wang X, Travis OK, Shields CA, Tardo GA, Giachelli C, Nutter CW, Glenn HL, Cooper OG, Davis T, Thomas R, Williams JM, Cornelius DC, NLRP3 inhibition improves maternal hypertension, inflammation, and vascular dysfunction in response to placental ischemia. American journal of physiology. Regulatory, integrative and comparative physiology, 2023 Apr 1;324(4):R556-R5672023
Shields CA, Wang X, Cornelius DC, Sex differences in cardiovascular response to sepsis. American journal of physiology. Cell physiology, 2023 Feb 1;324(2):C458-C4662023
Ekperikpe US, Poudel B, Shields CA, Mandal S, Cornelius DC, Williams JM, Neutralizing MIP3α Reduces Renal Immune Cell Infiltration and Progressive Renal Injury in Young Obese Dahl Salt-Sensitive Rats. The Journal of pharmacology and experimental therapeutics, 2023 Mar;384(3):445-4542023
Poudel B, Shields CA, Ekperikpe US, Brown AK, Travis OK, Maury JC, Fitzgerald S, Smith SV, Cornelius DC, Williams JM, The SS(LepR) mutant rat represents a novel model to study obesity-induced renal injury before puberty. American journal of physiology. Regulatory, integrative and comparative physiology, 2022 Apr 1;322(4):R299-R3082022
Borges-Rodriguez M, Shields CA, Travis OK, Tramel RW, Baik CH, Giachelli CA, Tardo GA, Williams JM, Cornelius DC, Platelet Inhibition Prevents NLRP3 Inflammasome Activation and Sepsis-Induced Kidney Injury. International journal of molecular sciences, 2021 Sep 25;22(19)2021
Poudel B, Shields CA, Brown AK, Ekperikpe U, Johnson T, Cornelius DC, Williams JM, Depletion of macrophages slows the early progression of renal injury in obese Dahl salt-sensitive leptin receptor mutant rats. American journal of physiology. Renal physiology, 2020 Jun 1;318(6):F1489-F14992020
McPherson KC, Shields CA, Poudel B, Johnson AC, Taylor L, Stubbs C, Nichols A, Cornelius DC, Garrett MR, Williams JM, Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats. American journal of physiology. Renal physiology, 2020 Apr 1;318(4):F911-F9212020
Cornelius DC, Baik CH, Travis OK, White DL, Young CM, Austin Pierce W, Shields CA, Poudel B, Williams JM, NLRP3 inflammasome activation in platelets in response to sepsis. Physiological reports, 2019 May;7(9):e140732019
McPherson KC, Shields CA, Poudel B, Fizer B, Pennington A, Szabo-Johnson A, Thompson WL, Cornelius DC, Williams JM, Impact of obesity as an independent risk factor for the development of renal injury: implications from rat models of obesity. American journal of physiology. Renal physiology, 2019 Feb 1;316(2):F316-F3272019
Spires D, Poudel B, Shields CA, Pennington A, Fizer B, Taylor L, McPherson KC, Cornelius DC, Williams JM, Prevention of the progression of renal injury in diabetic rodent models with preexisting renal disease with chronic endothelin A receptor blockade. American journal of physiology. Renal physiology, 2018 Oct 1;315(4):F977-F9852018
Shields CA, McCalmon M, Ibrahim T, White DL, Williams JM, LaMarca B, Cornelius DC, Placental ischemia-stimulated T-helper 17 cells induce preeclampsia-associated cytolytic natural killer cells during pregnancy. American journal of physiology. Regulatory, integrative and comparative physiology, 2018 Aug 1;315(2):R336-R3432018
Brown AK, Nichols A, Coley CA, Ekperikpe US, McPherson KC, Shields CA, Poudel B, Cornelius DC, Williams JM, Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure. Frontiers in physiology, 2021;12:765305
Shields CA, Poudel B, McPherson KC, Brown AK, Ekperikpe US, Browning E, Sutton L, Cornelius DC, Williams JM, Treatment With Gemfibrozil Prevents the Progression of Chronic Kidney Disease in Obese Dahl Salt-Sensitive Rats. Frontiers in physiology, 2020;11:566403

Honors, Awards, and Recognition

Juan Carlos Romero and Water and Electrolyte Homeostasis Section Postdoctoral Research Recognition Award, American Physiological Society2023

Professional Membership and Service

American Physiological Society, Member2021 - Present

Committee Service

APS Water and Electrolyte Homeostasis Steering Committee, Steering Comittee Member2022 - 2024

Teaching Experience

PH723, Medicine, Lecture, Lecturer, Mechanisms of Drug ActionFall 2024
Graduate, Lecture, Facilitator, Responsible Conduct of ResearchSpring 2023