Gunjan Sharma, PhD
Instructor-Research
Department:
SOM-Cell and Molecular Biology
Email:
gsharma@umc.edu
Work Phone:
(601) 984-5350
Education
| University of Mississippi Medical Center, USA, Postdoctoral Research Fellow, Cell and Molecular Biology | 2025 |
| University of Nebraska Medical Center, USA, Postdoctoral Research Associate, Biochemistry and Molecular Biology | 2024 |
| Hebrew University of Jerusalem, Israel, Postdoctoral Research Fellow, Immunology and Cancer Research | 2021 |
| Banaras Hindu University, Varanasi, UP, India, PhD, Biotechnology | 2018 |
Current Positions
| Instructor, School of Medicine, Department of Cell and Molecular Biology | 07/2025 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Publications
Journal Article | |
| Abdullah KM, Sharma G, Anjum B, Alam MF, Yadav S, Singh Y, Sinha RA, Venkatesh V, Siddiqui JA, Chakravarti B, Insulin resistance: The central node of convergence between unfolded protein response, diabetes, and cancer. Molecular aspects of medicine, 2026 Apr;108:101458 | 2026 |
| Abdullah KM, Sharma G, Singh AP, Siddiqui JA, Nanomedicine in Cancer Therapeutics: Current Perspectives from Bench to Bedside. Molecular cancer, 2025 Jun 9;24(1):169 | 2025 |
| Kaushal JB, Raut P, Halder S, Alsafwani ZW, Parte S, Sharma G, Abdullah KM, Seshacharyulu P, Lele SM, Batra SK, Siddiqui JA, Oncogenic potential of truncated-Gli3 via the Gsk3β/Gli3/AR-V7 axis in castration-resistant prostate cancer. Oncogene, 2025 Apr;44(15):1007-1023 | 2025 |
| Chakravarti B, Tomar MS, Qais FA, Raza S, Abdullah KM, Sharma G, Tewari A, Yadav A, Gupta P, Chattopadhyay N, Shrivastava A, Sinha RA, Siddiqui JA, Alpha lipoic acid modulates metabolic reprogramming in breast cancer stem cells enriched 3D spheroids by targeting phosphoinositide 3-kinase: In silico and in vitro insights. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2025 Jun;187:118121 | 2025 |
| Takkar S, Sharma G, Kaushal JB, Abdullah KM, Batra SK, Siddiqui JA, From orphan to oncogene: The role of GPR35 in cancer and immune modulation. Cytokine & growth factor reviews, 2024 Jun;77:56-66 | 2024 |
| Sharma G, Sultana A, Abdullah KM, Pothuraju R, Nasser MW, Batra SK, Siddiqui JA, Epigenetic regulation of bone remodeling and bone metastasis. Seminars in cell & developmental biology, 2024 Feb 15;154(Pt C):275-285 | 2024 |
| Abdullah KM, Kaushal JB, Takkar S, Sharma G, Alsafwani ZW, Pothuraju R, Batra SK, Siddiqui JA, Copper metabolism and cuproptosis in human malignancies: Unraveling the complex interplay for therapeutic insights. Heliyon, 2024 Mar 15;10(5):e27496 | 2024 |
| Abdullah KM, Sharma G, Takkar S, Kaushal JB, Pothuraju R, Chakravarti B, Batra SK, Siddiqui JA, α-lipoic acid modulates prostate cancer cell growth and bone cell differentiation. Scientific reports, 2024 Feb 22;14(1):4404 | 2024 |
| Sharma G, Abdullah KM, Qais FA, Khan P, Cox JL, Sarwar T, Nasser MW, Batra SK, Siddiqui JA, Clofazimine inhibits small-cell lung cancer progression by modulating the kynurenine/aryl hydrocarbon receptor axis. International journal of biological macromolecules, 2024 Dec;282(Pt 3):136921 | 2024 |
| Abdullah KM, Sharma G, Qais FA, Khan I, Takkar S, Kaushal JB, Kanchan RK, Sarwar T, Chakravarti B, Siddiqui JA, Hydroxychloroquine interaction with phosphoinositide 3-kinase modulates prostate cancer growth in bone microenvironment: In vitro and molecular dynamics based approach. International journal of biological macromolecules, 2024 May;266(Pt 1):130912 | 2024 |
| Britan-Rosich Y, Ma J, Kotler E, Hassan F, Botvinnik A, Smith Y, Moshel O, Nasereddin A, Sharma G, Pikarsky E, Ross S, Kotler M, APOBEC3G protects the genome of human cultured cells and mice from radiation-induced damage. The FEBS journal, 2023 Apr;290(7):1822-1839 | 2023 |
| Siddiqui JA, Pothuraju R, Khan P, Sharma G, Muniyan S, Seshacharyulu P, Jain M, Nasser MW, Batra SK, Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia. Cytokine & growth factor reviews, 2022 Apr;64:71-83 | 2022 |
| Sharma G, Pothuraju R, Kanchan RK, Batra SK, Siddiqui JA, Chemokines network in bone metastasis: Vital regulators of seeding and soiling. Seminars in cancer biology, 2022 Nov;86(Pt 3):457-472 | 2022 |
| Mughees M, Kaushal JB, Sharma G, Wajid S, Batra SK, Siddiqui JA, Chemokines and cytokines: Axis and allies in prostate cancer pathogenesis. Seminars in cancer biology, 2022 Nov;86(Pt 3):497-512 | 2022 |
| Botvinnik A, Shivam P, Smith Y, Sharma G, Olshevsky U, Moshel O, Manevitch Z, Climent N, Oliva H, Britan-Rosich E, Kotler M, APOBEC3G rescues cells from the deleterious effects of DNA damage. The FEBS journal, 2021 Oct;288(20):6063-6077 | 2021 |
| Paul A, Hazra S, Sharma G, Guedes da Silva MFC, Koch B, Pombeiro AJL, Unfolding biological properties of a versatile dicopper(II) precursor and its two mononuclear copper(II) derivatives. Journal of inorganic biochemistry, 2017 Sep;174:25-36 | 2017 |
| Agrawal P, Singh RP, Sonali, Kumari L, Sharma G, Koch B, Rajesh CV, Mehata AK, Singh S, Pandey BL, Muthu MS, TPGS-chitosan cross-linked targeted nanoparticles for effective brain cancer therapy. Materials science & engineering. C, Materials for biological applications, 2017 May 1;74:167-176 | 2017 |
| Mukhopadhyay S, Singh RS, Paitandi RP, Sharma G, Koch B, Pandey DS, Influence of substituents on DNA and protein binding of cyclometalated Ir(iii) complexes and anticancer activity. Dalton transactions (Cambridge, England : 2003), 2017 Jul 4;46(26):8572-8585 | 2017 |
| Singh RP, Sharma G, Sonali, Singh S, Bharti S, Pandey BL, Koch B, Muthu MS, Chitosan-folate decorated carbon nanotubes for site specific lung cancer delivery. Materials science & engineering. C, Materials for biological applications, 2017 Aug 1;77:446-458 | 2017 |
| Sharma G, Rana NK, Singh P, Dubey P, Pandey DS, Koch B, p53 dependent apoptosis and cell cycle delay induced by heteroleptic complexes in human cervical cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017 Apr;88:218-231 | 2017 |
| Agrawal P, Sonali, Singh RP, Sharma G, Mehata AK, Singh S, Rajesh CV, Pandey BL, Koch B, Muthu MS, Bioadhesive micelles of d-α-tocopherol polyethylene glycol succinate 1000: Synergism of chitosan and transferrin in targeted drug delivery. Colloids and surfaces. B, Biointerfaces, 2017 Apr 1;152:277-288 | 2017 |
| Goutam J, Sharma G, Tiwari VK, Mishra A, Kharwar RN, Ramaraj V, Koch B, Isolation and Characterization of "Terrein" an Antimicrobial and Antitumor Compound from Endophytic Fungus Aspergillus terreus (JAS-2) Associated from Achyranthus aspera Varanasi, India. Frontiers in microbiology, 2017;8:1334 | 2017 |
| Singh RP, Sharma G, Sonali, Agrawal P, Pandey BL, Koch B, Muthu MS, Transferrin receptor targeted PLA-TPGS micelles improved efficacy and safety in docetaxel delivery. International journal of biological macromolecules, 2016 Feb;83:335-44 | 2016 |
| Sonali, Singh RP, Sharma G, Kumari L, Koch B, Singh S, Bharti S, Rajinikanth PS, Pandey BL, Muthu MS, RGD-TPGS decorated theranostic liposomes for brain targeted delivery. Colloids and surfaces. B, Biointerfaces, 2016 Nov 1;147:129-141 | 2016 |
| Hazra S, Paul A, Sharma G, Koch B, da Silva MFCG, Pombeiro AJL, Sulfonated Schiff base Sn(IV) complexes as potential anticancer agents. Journal of inorganic biochemistry, 2016 Sep;162:83-95 | 2016 |
| Singh RP, Sharma G, Sonali, Singh S, Kumar M, Pandey BL, Koch B, Muthu MS, Vitamin E TPGS conjugated carbon nanotubes improved efficacy of docetaxel with safety for lung cancer treatment. Colloids and surfaces. B, Biointerfaces, 2016 May 1;141:429-442 | 2016 |
| Singh RP, Sharma G, Sonali, Singh S, Patne SCU, Pandey BL, Koch B, Muthu MS, Effects of transferrin conjugated multi-walled carbon nanotubes in lung cancer delivery. Materials science & engineering. C, Materials for biological applications, 2016 Oct 1;67:313-325 | 2016 |
| Singh RS, Gupta RK, Paitandi RP, Dubey M, Sharma G, Koch B, Pandey DS, Morphological tuning via structural modulations in AIE luminogens with the minimum number of possible variables and their use in live cell imaging. Chemical communications (Cambridge, England), 2015 Jun 4;51(44):9125-8 | 2015 |
| Paul A, Anbu S, Sharma G, Kuznetsov ML, Guedes da Silva MF, Koch B, Pombeiro AJ, Intracellular detection of Cu(2+) and S(2-) ions through a quinazoline functionalized benzimidazole-based new fluorogenic differential chemosensor. Dalton transactions (Cambridge, England : 2003), 2015 Oct 14;44(38):16953-64 | 2015 |
| Paul A, Anbu S, Sharma G, Kuznetsov ML, Koch B, Guedes da Silva MF, Pombeiro AJ, Synthesis, DNA binding, cellular DNA lesion and cytotoxicity of a series of new benzimidazole-based Schiff base copper(II) complexes. Dalton transactions (Cambridge, England : 2003), 2015 Dec 14;44(46):19983-96 | 2015 |
| Paitandi RP, Gupta RK, Singh RS, Sharma G, Koch B, Pandey DS, Interaction of ferrocene appended Ru(II), Rh(III) and Ir(III) dipyrrinato complexes with DNA/protein, molecular docking and antitumor activity. European journal of medicinal chemistry, 2014 Sep 12;84:17-29 | 2014 |
| Gupta RK, Sharma G, Pandey R, Kumar A, Koch B, Li PZ, Xu Q, Pandey DS, DNA/protein binding, molecular docking, and in vitro anticancer activity of some thioether-dipyrrinato complexes. Inorganic chemistry, 2013 Dec 16;52(24):13984-96 | 2013 |
| Gupta RK, Pandey R, Sharma G, Prasad R, Koch B, Srikrishna S, Li PZ, Xu Q, Pandey DS, DNA binding and anti-cancer activity of redox-active heteroleptic piano-stool Ru(II), Rh(III), and Ir(III) complexes containing 4-(2-methoxypyridyl)phenyldipyrromethene. Inorganic chemistry, 2013 Apr 1;52(7):3687-98 | 2013 |
| Siddiqui JA, Swarnkar G, Sharan K, Chakravarti B, Sharma G, Rawat P, Kumar M, Khan FM, Pierroz D, Maurya R, Chattopadhyay N, 8,8''-Biapigeninyl stimulates osteoblast functions and inhibits osteoclast and adipocyte functions: Osteoprotective action of 8,8''-biapigeninyl in ovariectomized mice. Molecular and cellular endocrinology, 2010 Jul 29;323(2):256-67 | 2010 |
Editorial | |
| Sharma G, Ponzetti M, Siddiqui JA, Editorial: Bone metastasis in the milieu of osteoimmunology. Frontiers in immunology, 2023;14:1265434 | 2023 |
| Sharma G, Dal Col J, Siddiqui JA, Editorial: Rising stars in molecular and cellular oncology 2022. Frontiers in oncology, 2023;13:1136335 | 2023 |
| Sharma G, Barbieri I, Blandino G, Poli V, Siddiqui JA, Editorial: Roles of non-coding RNAs in tumor growth and development. Frontiers in oncology, 2022;12:1098315 | 2022 |