Jay G. Shake, MD
Professor
Department:
SOM-Surgery-Cardiothoracic
Email:
jshake@umc.edu
Work Phone:
(601) 984-5174
Education
| University of Minnesota, MD, Medicine | 1997 |
| University of Minnesota, MS, Physiology | 1991 |
| University of Minnesota, BA, Physiology | 1988 |
| The Johns Hopkins Hospital, General Surgery, Surgery | |
| The Johns Hopkins Hospital, Surgical Critical Care Fellowship, Critical Care | |
| Mayo Clinic, visiting fellow, Surgery | |
| The Johns Hopkins Hospital, Cardiac Surgery, Surgery | |
| The Johns Hopkins Hospital, General Surgery, Surgery |
Specialty Certification Licensure
| DEA, Controlled Substance Registration Certificate | 01/2015 - Present |
| NPI | |
| Licensure, MS State Board of Medical Licensure | 09/2014 - 06/2015 |
| Certification, American Board of Surgery | 09/2011 - 07/2022 |
| Certification, American Board of Thoracic Surgery | 06/2007 - 12/2017 |
| Certification, American Board of Surgery | 10/2005 - 07/2016 |
Current Positions
| Associate Chief of Staff, School of Medicine | 07/2023 - Present |
| Associate Professor, School of Medicine, Department of Surgery | 09/2014 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Publications
Journal Article | |
| Khawaja M Talha, Joseph M Brewer, Jay G Shake, Ashok C Jeyakumar, Adam N Protos, Gabriel A Hernandez Ventilatory Failure And Pulmonary Embolism In Covid-19 Requiring Enhanced Venous Drainage For Extracorporeal Membrane Oxygenation Port J Card Thorac Vas Surg. 2023 Jan 14;29(4):51-54 | 2023 |
| Greenleaf CE, Griffin LA, Shake JG, Orr WS. Hypertensive crisis secondary to pheochromocytoma. Proc Bayl Univ Med Center 2017 Jul;30(3):314-315 | 2017 |
| Choi CH, Konda S., Shake JG. Angiosarcoma of the right atrium presenting as hemoptysis. Proc (Bayl Univ Med Center). 2016 Jan; 29(1):79-80. | 2016 |
| Dixon JL, Stagg HW, Wehbe-Janek H, Jo C, Culp WC Jr, Shake JG. A standard handoff improves cardiac surgical patient transfer: operating room to intensive care unit. J Healthc Qual. 2015 Jan-Feb;37(1):22-32. | 2015 |
| Dixon JL, Papaconstantinou HT, Hodges B, Korsmo RS, Jupiter D, Shake JG, Sareyyupoglu B, Rascoe PA, Reznik SI. Redundancy and variability in quality and outcome reporting for cardiac and thoracic surgery. Proc (Bayl Univ Med Cent). 2015 Jan;28(1):14-7. | 2015 |
| Elahi MM, Choi CH, Konda S, Shake JG. Consequence of patient substitution of nattokinase for warfarin after aortic valve replacement with a mechanical prosthesis. Proc (Bayl Univ Med Cent). 2015 Jan;28(1):81-2. | 2015 |
| Shake JG, Pronovost PJ, Whitman GJ. Cardiac surgical ICU care: eliminating "preventable" complications. J Card Surg. 2013 Jul;28(4):406-13. doi: 10.1111/jocs.12124. Epub 2013 May 30. | 2013 |
| Emery RW, Emery AM, Raikar GV, Shake JG. Anticoagulation for mechanical heart valves: a role for patient based therapy J Thromb Thrombolysis. 2008 Feb;25(1):18-25. Epub 2007 Dec 4. | 2008 |
| Emery RW, Emery AM, Krogh C, Shake JG, Holter AR, Blake DP, Raikar GV. The St. Jude Medical cardiac valve prosthesis: long-term follow up of patients having double valve replacement. J Heart Valve Dis. 2007 Nov;16(6):634-40. | 2007 |
| Kaushal S, Shake JG, Yuh DD. Mycotic innominate artery pseudoaneurysm presenting as an embolic stroke. J Thorac Cardiovasc Surg. 2005 Apr;129(4):945-6. | 2005 |
| Dodd-o JM, Welsh LE, Salazar JD, Walinsky PL, Peck EA, Shake JG, Caparrelli DJ, Ziegelstein RC, Zweier JL, Baumgartner WA, Pearse DB. Effect of NADPH oxidase inhibition on cardiopulmonary bypass-induced lung injury. Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H927-36. | 2004 |
| Dodd-o JM, Welsh LE, Salazar JD, Walinsky PL, Peck EA, Shake JG, Caparrelli DJ, Bethea BT, Cattaneo SM, Baumgartner WA, Pearse DB. Effect of bronchial artery blood flow on cardiopulmonary bypass-induced lung injury. Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H693-700. Epub 2003 Oct 16. | 2004 |
| Caparrelli DJ, Cattaneo SM, Bethea BT, Shake JG, Eberhart C, Blue ME, Marbán E, Johnston MV, Baumgartner WA, Gott VL. Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia. Ann Thorac Surg. 2002 Sep;74(3):838-44; discussion 844-5 | 2002 |
| Shake JG, Gruber PJ, Baumgartner WA, Senechal G, Meyers J, Redmond JM, Pittenger MF, Martin BJ. Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects. Ann Thorac Surg. 2002 Jun;73(6):1919-25; discussion 1926. | 2002 |
| Caparrelli DJ, Shake JG, Cattaneo SM 2nd, Chang BY, Baumgartner WA, Conte JV Jr, George P. Heterotopic abdominal heart transplantation: a pilot study Curr Opin Cardiol. 2002 Mar;17(2):145-51. | 2002 |
| Shake JG, Larson DW, Kulick DM, Salerno CT, Bianco RW, Bolman RM. Transmural atrial insulating lesions using epicardially applied radiofrequency energy coupled with saline irrigation. J Invest Surg. 2002 Mar-Apr;15(2):101-7. | 2002 |
| Gott VL, Cameron DE, Alejo DE, Greene PS, Shake JG, Caparrelli D, Deitz HC. Aortic root replacement in 271 Marfan patients: a 24-year experience. Ann Thorac Surg. 2002 Feb;73(2):438-43. | 2002 |
| Kim AY1, Walinsky PL, Kolodgie FD, Bian C, Sperry JL, Deming CB, Peck EA, Shake JG, Ang GB, Sohn RH, Esmon CT, Virmani R, Stuart RS, Rade JJ. Early loss of thrombomodulin expression impairs vein graft thromboresistance: implications for vein graft failure. Circ Res. 2002 Feb 8;90(2):205-12. | 2002 |
| Shake JG, Peck EA, Marban E, Gott VL, Johnston MV, Troncoso JC, Redmond JM, Baumgartner WA. Pharmacologically induced preconditioning with diazoxide: a novel approach to brain protection. Ann Thorac Surg. 2001 Dec;72(6):1849-54. | 2001 |
| Caparrelli DJ1, Shake JG, Baumgartner WA, Conte JV. Heterotopic abdominal heart transplantation: the answer to the donor shortage? J Heart Lung Transplant. 2001 Feb;20(2):187-188. | 2001 |
| Perler BA, Murphy K, Sternbach Y, Gailloud P, Shake JG. Immediate postoperative thrombolytic therapy: an aggressive strategy for neurologic salvage when cerebral thromboembolism complicates carotid endarterectomy. J Vasc Surg. 2000 May;31(5):1033-7. | 2000 |
| Shake JG. Farewell to a surgical giant. A tribute to C. Walton Lillehei, M.D., Ph.D. Minn Med. 1999 Dec;82(12):60-1. | 1999 |
| Salerno CT, Ouyang DW, Pederson TS, Larson DM, Shake JG, Johnson EM, Maddaus MA Surgical therapy for pulmonary aspergillosis in immunocompromised patients. Ann Thorac Surg. 1998 May;65(5):1415-9 | 1998 |
| Shake JG, Larson DW, Salerno CT, Bianco RW, Bolman RM. The role of electrolyte in lesion size using an irrigated radiofrequency electrode. J Invest Surg. 1997 Nov-Dec;10(6):339-46; discussion 346-8. | 1997 |
| Opsahl JA, Abraham PA, Shake JG, Katz SA. Role of renin isoelectric heterogeneity in renal storage and secretion of renin. J Am Soc Nephrol. 1993 Oct;4(4):1054-63. | 1993 |
| Shake JG, Kronz JD, Rodeberg DA, Colombani PM Foreign bodies within the appendix: a case report and literature review. Contemporary Surgery 200;56(1):10-14 | |
| Carter KT, Kutcher ME, Shake JG, Panos Al, Cochran RP, Creswell LL, Copeland HJ. Heparin-Sparing Anticoagulation Strategies Are Viable Options for Patients on Veno-Venous ECMO J Surge Res. 2019 Nov;243:399-409. doi: 10.1016/j.jss.2019.05.050. Epub 2019 Jul 2.PMID:31277018 | |
| Arora RC, Chatterjee S, Shake JG, Hirose H, Engelman DT, Rabin J, Firstenberg M, Moosdorf RGH, Geller CM, Hiebert B, Whitman GJ, Society of Thoracic Surgeons Workforce for Critical Care (STS WFCC). Survey of Contemporary Cardiac Surgery Intensive Care Unit Models in the United States Ann Thorac Surg. 2020 Mar;109(3):702-710. doi:10.1016/j.athoracsur.2019.06.077.Epub 2019 Aug 15.PMID: 31421102 | |
Dissertation | |
| Shake JG (Advisor Stephen A. Katz Ph.D.) Renin synthesis inhibition in the in-vivo perfused rabbit kidney. | 1991 |
Book Chapter | |
| Shake JG, Williams GM Aortic Dissection The Johns Hopkins Manual of Cardiothoracic Surgery. Yuh DD, Vricella LA (eds): McGraw-Hill 2007 | |
| Barreiro CJ, Shake JG Reoperative coronary artery bypass surgery The Johns Hopkins Textbook of Cardiothoracic Surgery. Yuh DD, Vricella LA, Yang S, Doty J (eds): McGraw-Hill 2014. | |
| Shake JG, Ciceri DP Cardiovascular Pharmacology Current Surgical Therapy (11th edition). Cameron JL and Cameron AM (eds). Elsevier 2014. | |
| Shake JG, Ciceri DP. Inotropes Current Therapy in Thoracic and Cardiovascular Surgery (2nd edition). Yang SC and Cameron DE (eds). Elsevier 2014. | |
Electronic Publications | |
| Greenleaf CE, Shake JG, Cheng AM. Post-operative Care of the Cardiac Surgical Patient. Society of Thoracic Surgery (STS) eBook. 8/2017 | |
Presentations
| National and International Invited Seminars/Lectures, Heparin-Sparing Anticoagulation Strategies are Viable Options for Patients on Veno-venous ECMO. Kristen Carter, Ramola Panchal, Jay Shake, Anthony Panos, Richard P Cochran, Lawrence C. Creswell, Matthew E. Kutcher, and Hannah Copeland., Acadmic Surgical Congress, Houston, TX | 02/2019 |
| National and International Invited Seminars/Lectures, Society of Thoracic Surgeons Annual Meeting- Critical Care Symposium. Session organizer and moderator, 54th Annual Meeting Society of Thoracic Surgeons, Fort Lauderdale, FL | 01/2018 |
| Poster Presentation, Pheochromocytoma: A case of devastating respiratory failure with ECMO salvage, 69th Annual Meeting of the Southwest Surgical Congress, Maui, HI | 04/2017 |
| National and International Invited Seminars/Lectures, Society of Thoracic Surgeons- Poster Crawl. Moderator, 53rd Annual Meeting of the Society of Thoracic Surgeons, Houston, TX | 01/2017 |
| National and International Invited Seminars/Lectures, Critical Care Parallel Session- Moderator, 53rd Annual Meeting of the Society of Thoracic Surgeons, Houston, TX | 01/2017 |
| National and International Invited Seminars/Lectures, STS/AATS Critical Care Symposium - Discussant, 53rd Annual Meeting of the Society of Thoracic Surgeons, Houston, TX | 01/2017 |
| State/Local Invited Seminars/Lectures, A Ferrari Team Approach to Critical Care Management of the Congenital Heart Patient, Innovations in the Treatment of Congenital Heart Disease. University of Mississippi Medical Center, Jackson, MS | 04/2016 |
| Poster Presentation, Implementing Lean Methodology to Improve Operative Efficiency in Cardiac Surgery, 68th Annual meeting of the Southwestern Surgical Congress Annual Meeting, Coronado, CA | 04/2016 |
| National and International Invited Seminars/Lectures, Critical Care Sessions - STS/SCA Lectures. Session organizer and moderator, 52nd Annual Meeting of the Society of Thoracic Surgeons, Phoenix, AZ | 01/2016 |
| National and International Invited Seminars/Lectures, Billing and Coding in the Cardiothoracic Intensive Care Unit. Early Riser Session., 52nd Annual Meeting of the Society of Thoracic Surgeons, Phoenix, AZ | 01/2016 |
| National and International Invited Seminars/Lectures, Society of Thoracic Surgeons- Poster Crawl. Moderator, 52nd Annual Meeting of the Society of Thoracic Surgeons, Phoenix, AZ | 01/2016 |
| National and International Invited Seminars/Lectures, Critical Care Session - STS/SCA lectures. Session organizer and moderator, 51st Annual Meeting of the Society of Thoracic Surgeons, San Diego, CA | 01/2015 |
| National and International Invited Seminars/Lectures, Billing and Coding in the Cardiothoracic Intensive Care Unit - Early Riser Session, 51st Annual Meeting of the Society of Thoracic Surgeons, San Diego, CA | 01/2015 |
| Society of Thoracic Surgeons Roundtable Video Series - ECMO, 51st Annual Meeting of the Society of Thoracic Surgeons, San Diego, CA | 01/2015 |
| National and International Invited Seminars/Lectures, Society of Thoracic Surgeons- Poster Crawl. Moderator, 51st Annual Meeting of the Society of Thoracic Surgeons, San Diego, CA | 01/2015 |
| Invited Symposia, Checklists, handoffs, and multidisciplinary communication in the cardiac ICU, Bakoulev/Johns Hopkins Hospital Cardiovascular Critical Care Symposia, Moscow, Russia | 11/2014 |
| Invited Symposia, Blood product utilization in the CTICU, Bakoulev/Johns Hopkins Hospital Cardiovascular Critical Care Symposia, Moscow, Russia | 11/2014 |
| National and International Invited Seminars/Lectures, Billing and Coding in the Cardiothoracic Intensive Care Unit, Early Riser Session. 50th Annual Meeting of the Society of thoracic Surgeons, Orlando, FL | 10/2014 |
| National and International Invited Seminars/Lectures, Society of Thoracic Surgeons- Poster Crawl. Moderator, Society of Thoracic Surgeons, Orlando, FL | 01/2014 |
| National and International Invited Seminars/Lectures, Critical Care Symposium - Moderator, 50th Annual Meeting of the Society of Thoracic Surgeons, Orlando, FL | 01/2014 |
| National and International Invited Seminars/Lectures, Apples to apples? Redundancy and variability in quality and outcomes reporting for cardiac and thoracic surgery, 50th Annual Congress of the Society of Thoracic Surgeons, Orlando, FL | 01/2014 |
| National and International Invited Seminars/Lectures, Implementation of a standard handoff process facilitates transfer of care of cardiac surgical patients from operating room to ICU, 99th Annual Clinical Congress of The American College of Surgeons, Washington, DC | 10/2013 |
| State/Local Invited Seminars/Lectures, Operating room to ICU handoffs: Cardiac Surgery, Quality Improvement in Healthcare Symposium. Scott & White Memorial Hospital, Temple, Tx | 09/2013 |
| Regional Invited Seminars/Lectures, Multidisciplinary collaboration to produce a high quality CTICU, Department of Surgery Grand Rounds, Atlanta, GA | 08/2013 |
| National and International Invited Seminars/Lectures, Cardiothoracic ICUs should only be managed by a board certified intensivist. PRO/CON debate, 49th Annual Congress of the Society of Thoracic Surgeons, Los Angeles, CA | 01/2013 |
| National and International Invited Seminars/Lectures, Anticoagulation for mechanical heart valves: a role for patient based therapy., 9th National Conference of Anticoagulant Therapy, Chicago, IL | 05/2007 |
| State/Local Invited Seminars/Lectures, Innovations in Cardiovascular Surgery, Medicine Grand Rounds, Fairmont, MN | 01/2007 |
| National and International Invited Seminars/Lectures, The role of NADPH oxidase in ischemia-reperfusion lung injury., 2nd Annual Meeting of the American Transplant Congres, Washington, DC | 04/2002 |
| National and International Invited Seminars/Lectures, Reduction of neurologic injury following aortic cross-clamp using the mitochondrial potassium channel opener diazoxide., 48th Annual Meeting of the Southern Thoracic Surgical Association | 11/2001 |
| National and International Invited Seminars/Lectures, Pharmacologic preconditioning significantly ameliorates neurological injury in a model of spinal cord ischemia., 48th Annual Meeting of the Southern Thoracic Surgical Association, San Antonio, TX | 11/2001 |
| National and International Invited Seminars/Lectures, Cellular cardiomyoplasty with allogeneic mesenchymal stem cells results in improved cardiac performance in a swine model of myocardial infarction., American Heart Association, Anaheim, CA | 11/2001 |
| National and International Invited Seminars/Lectures, Heterotopic abdominal heart transplantation: the answer to the donor shortage?, 21st Annual Meeting and Scientific Sessions of the international Society of Heart and Lung Transplantation, Vancouver, BC, Canada | 04/2001 |
| National and International Invited Seminars/Lectures, Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects., Society of Thoracic Surgeons 37th Annual Meeting | 01/2001 |
| National and International Invited Seminars/Lectures, Pharmacologically induced preconditioning with diazoxide: a novel approach to brain protection., Society of Thoracic Surgeons 37th Annual Meeting | 01/2001 |
| National and International Invited Seminars/Lectures, Altered thrombomodulin expression diminishes the thromboresistance of autologous vein., American Heart Association | 11/2000 |
| National and International Invited Seminars/Lectures, Pre-test mapping with cold Ringer's solution via screw-tip catheter before radiofrequency ablation., American Heart Association | 11/1995 |
| National and International Invited Seminars/Lectures, Intramural ablation using screw-tip catheter and saline electrode produces predictable lesion size., American Heart Association | 11/1995 |
| National and International Invited Seminars/Lectures, Improving intramural radiofrequency ablation utilizing a screw-tip catheter and saline infusion "virtual electrode", North American Society of Pacing and Electrophysiology | 05/1995 |
| National and International Invited Seminars/Lectures, Angiotensin II induces actin polymerization within the glomerular filtration barrier: possible role in the regulation of ultrafiltration., American Society of Nephrology | 11/1992 |
| National and International Invited Seminars/Lectures, Protein Synthesis inhibition does not affect acute renin synthesis (RS) in the in-vivo perfused rabbit kidney., American Society of Nephrology | 12/1990 |
Honors, Awards, and Recognition
| LEAP Leader Award - 100 day Workout for Growth and Leakage, University of Mississippi Medical Center Administration | 2016 |
| President's Award 2014, Baylor Scott & White Health | 2014 |
| George D. Zuidema Surgical Residents Research Award, Johns Hopkins Department of Surgery | 2002 |
| Resident Research Award- top in USA, Thoracic Surgery Directors Association | 2001 |
| The Irene Piccinni Investigator in Cardiac Surgery, Johns Hopkins Hospital Cardiac Surgery | 1999 |
| Surgical Student Research Award, Association for Academic Surgery | 1997 |
| AOA membership, Alpha Omega Alpha National Honor Medical Society | 1996 |
| Gerald P. Plaisance Scholarship, Minnesota Medical Foundation | 1996 |
| Research Scholarship- Large animal study in xenotransplantation, Minnesota Medical Foundation | 1995 |
| MMF Centennial Scholarship, Minnesota Medical Foundation | 1995 |
| Walter and Elva Lovell Scholarship, Minnesota Medical Foundation | 1995 |
| James H. Moller Scholarship, American Heart Association - MN affiliate | 1995 |
| Minnesota Medical Foundation Scholarship, Minnesota Medical Foundation | 1994 |
Professional Membership and Service
| Society of Critical Care Medicine, Member | 2012 - Present |
| American College of Surgeons, Fellow | 2009 - Present |
| The Society of Thoracic Surgeons, Member | 2008 - Present |
| The Johns Hopkins Medical and Surgical Association, Member | 1997 - Present |
| American Medical Association, Member |
Committee Service
| THE UNIVERSITY HOSPITALS AND CLINICS-CRITICAL CARE, Chair | 2015 - Present |
| MEDICAL CENTER-INSTITUTIONAL REVIEW BOARD 2, Member | 2015 - 2015 |
| Cardiothoracic Surgery Clinical Competency Committee, Member | 2014 - Present |
| VAD and Heart Transplant QAPI, Member | 2014 - Present |
| Society of Thoracic Surgeons- ICU Workforce, Task Force Member | 2012 - Present |
| Society of Critical Care Medicine, In-Training Section, Secretary | 2012 - 2014 |
| VAT Committee (Value Analysis Team), Member | |
| Mortality Review Committee, Chair |
Teaching Experience
| Medicine, Course, Preceptor, Surgical Critical Care Clerkship | Annual |
Directed Student Learning
| Preceptor, Advised: Charles Choi | 2014 - 2016 |
| Preceptor | 2013 - Present |
Fellows supervised
| Cardiothoracic Surgery- UMMC, Preceptor, 0 fellows supervised | 07/2015 - 06/2017 |
| Cardiothoracic Surgery, Attending Physician, 4 fellows supervised, CVICU- critical care | 09/2014 - Present |
| Cardiac Surgery- Johns Hopkins, Preceptor, 0 fellows supervised | 07/2013 - 06/2014 |
| CT Surgery- Baylor Scott & White, Preceptor, 0 fellows supervised | 07/2012 - 06/2013 |
Residency Training
| Anesthesiology- UMMC, Preceptor | 2016 - Present |
| Surgery- UMMC, Attending Physician | 2016 - 06/2017 |
| Anesthesiology- UMMC, Attending Physician | 2016 - 06/2017 |
| Anesthesiology- UMMC, Preceptor | 2015 - 06/2016 |
| Surgery- Baylor Scott & White, Preceptor | 2013 - Present |
| Surgery- Baylor Scott & White, Preceptor | 2013 - Present |
| Surgery- Baylor Scott & White, Preceptor | 2013 - Present |
| Surgery- Baylor Scott & White, Preceptor | 2011 - 01/2014 |