James P. Shaffery

James P. Shaffery

PROFESSOR EMERITUS

Department:
SOM-Psychiatry

Email:
jshaffery@umc.edu

Biography

My research focuses upon the study of the basic mechanisms underlying the developmental function for rapid eye-movement (REM) sleep in brain maturation, the "Ontogenetic Hypothesis." Our early work on cats and rats in this area has provided a major proportion of the available data that supports the ontogenetic hypothesis, which posits a role for REM sleep in cortical development. Our work has uncovered some of the electrophysiological and molecular mechanisms that contribute to the effects the REM sleep state has on synaptic plasticity during development of both visual cortex and hippocampus. Research in my laboratory also has provided the first data demonstrating that REM sleep deprivation during an early critical period directly affects plasticity mechanisms involved in synaptic connectivity in the developing brain. My work in this area also includes the develop of a novel, computer controlled method for automatically manipulating REM sleep that is not subject to many of the critiques of the typically used ‘flower pot’ techniques, while being just as effective in reducing REM sleep but without disturbing slow wave sleep amounts. Overall, I have a demonstrated record of successful and productive research on REM sleep and its role in brain maturation utilizing both in vivo and in vitro electrophysiological techniques. Our work on synaptic plasticity studies of long-term potentiation (LTP) and long-term-depression (LTD) induction in brain slices have demonstrated that REM sleep deprivation in early life affects LTP and LTD in both visual cortex and hippocampus.

Education

University of Texas Southwestern Medical School, INRSA/HIMH, Sleep Neurophysiology1993
University of Texas Southwestern Medical School, Post-Doctoral Fellow, Sleep Neurophysiology1991
Oxford Univeristy, DPhil, Zoology/Ethology1984
Castleton State College, BA, Psychology1978
Castleton State College, AA, Chemistry1978

Current Positions

Assistant Professor, School of Graduate School in the Health Sciences, Department of Pharmacology / Toxicology07/2003 - Present
Associate Professor, School of Graduate School in the Health Sciences07/2003 - Present
Associate Professor, School of Medicine, Department of Psychiatry07/2002 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Assistant Professor, University of Mississippi Medical Center, School of Medicine, Department of Psychiatry08/1995 - 06/2002
Assistant Professor, U.T. Southwestern Medical center at Dallas, Department of Psychiatry1994 - 1995
Instructor, U. T. Southwestern Medical Center, School of , Department of Psychiatry1993 - 1994
NIMH INRSA Postdoctoral Fellow, U.T. Southwestern Medical Center at Dallas, Department of Psychiatry1990 - 1993
Postdoctoral Research Fellow, U.T. Southwestern Medical Center at Dallas, School of1988 - 1989
Visiting Assistant Professor/Research Fellow, University of Arkansas, School of1985 - 1987
Research Associate, Walla Walla College, Department of Biological Sciences06/1983 - 12/1985

Sponsored Program Funding

Extramural, Mechanisms of Seizure in
Pregnancy and Preeclampsia, NIH/ National Heart Lung and Blood Institute
10/2021 - 09/2022
Extramural, EEG Telemetry in Monkeys: Potential Markers of Benzodiazepine Action, NIH/ NIDA07/2019 - 06/2021
Intramural, Discriminating between anxiolytic and sedative actions of Benzodiazepine-type compounds, UMMC Institutional Reasearch Support Program06/2019 - 04/2021
Extramural, Astrocyte gap junctions, myelin integrity and depression-like behaviors, NIH/ National Institute of Mental Health07/2017 - 06/2018
Extramural, Center for Psychiatric Neuroscience, NIH/National Institute of General Medical Sciences01/2016 - 01/2018
Extramural, Center for Psychiatric Neuroscience, NIH/National Institute of General Medical Sciences01/2015 - 01/2016
Extramural, "Effects of early-life sleep abnormalities in the production of depressive-like features in a rat model of human MDD", Center for Research Excellence in Psychiatric Neuroscience-NIH/NCRR01/2009 - 12/2011
Extramural, Effects of eszopiclone (ESZ) and/or fluoxetine (FLX) on hippocampal neurogenesis in sleep-deprived (SD) rats, Sepracor, Inc.09/2007 - 08/2009
Extramural, Center for Research Excellence in Psychiatric Neuroscience, National Center for Research Resources07/2007 - 12/2012
Intramural, "REM Sleep and Developmental Synaptic Plasticity", University of Mississippi Medical Center Intramural Research Support Program01/2006 - 12/2007
Extramural, Brain Maturation: Function of Rapid Eye-Movement Sleep"., Supplement to NIH/NINDS/NIMH Grant (NS3172-06 2A)04/2004 - 03/2006
Extramural, Center for Research Excellence in Psychiatric Research, NIH/National Center for Research Resources09/2002 - 09/2007
Extramural, "Brain Maturation: Function of Rapid Eye-Movement Sleep"., NIH/NINDS/NIMH Grant (NS31720-06 2A)04/2001 - 03/2005
Intramural, "The Effects of Irradiation on Neonatal Sleep"., UMMC, Department of Psychiatry and Human Behavior01/2001 - 12/2002
Intramural, "The Effects of MK-801 on REMS and Brain Development in Critical Period Kittens"., UMMC Institutional Research Support Program01/2000 - 12/2001
Intramural, "Modeling Suicide in a New Animal Paradigm of Human Depression"., American Suicide Foundation/UMMC01/1998 - 12/1999
Extramural, "Cerebral Monoamines in an Animal Model of Human Depressive Disorder"., Oak Ridge Associated Universities01/1997 - 12/1998
Extramural, "Brain Maturation: Function of Rapid Eye-Movement Sleep"., NIH/NINDS Grant (NS31720)01/1995 - 12/1997
Extramural, "Brain Maturation: Function of Rapid Eye-Movement Sleep"., NIN/NINDS Grant (NS31720)01/1993 - 12/1995
Extramural, "Testing the Ontogenetic Hypothesis of REM Sleep"., NIH / NINH INRSA09/1990 - 08/1993
Intramural, "Developmental consequences of REM Sleep in Kitten Visual Cortex"., NIH/UT Southwestern Institutional Biomedical Research Support Grant09/1988 - 08/1990
Intramural, "Sleep Physiology and Behavior of Mallard"., NIH/UArkansas Institutional Biomedical Research Support01/1987 - 07/1988
Extramural, "Telemetric Studies In Bobwhite Behavior"., Arkansas Game and Fish Commission01/1986 - 12/1987

Publications

Journal Article

Jones-Muhammad M, Shao Q, Cain-Shields L, Shaffery J P, & Warrington J P Acid Sensing Ion Channel 2a Is Reduced in the Reduced Uterine Perfusion Pressure Mouse Model and Increases Seizure Susceptibility in Pregnant Mice Cells, 10(5), 1135. doi:10.3390/cells100511352021
Ou Y, Clifton B A, Li J, Chen T, Huang J, Li N, Wu L, Sandlin D, Allison J, Shaffery J P, Fan F, Roman R J, Zhou W, Pang Y, Zhu H, Traumatic brain injury induced by exposure to blast overpressure via the ear canal Neural Regen Res, 17(1), 115-121. doi:10.4103/1673-5374.3143112021
Wang S L W, Zhang H, Liu Y, Li L, Jefferson J R, Guo Y, Li M, Gao W, Fang X, Paul I A, Rajkowska G, Shaffery J P, Mosley T H, Hu X, Liu R, Wang Y, Yu H, Roman R J and Fan F Aging exacerbates impairments of cerebral blood flow autoregulation and cognition in diabetic rats Geroscience. doi:10.1007/s11357-020-00233-w2020
Himel AR, Cabral SA, Shaffery JP and Grayson BE Anxiety behavior and hypothalamic-pituitary-adrenal axis altered in a female rat model of vertical sleeve gastrectomy PLoS ONE, 13(7), e0200026. doi:10.1371/journal.pone.02000262018
Wallace K, Bean C, Bowles T, Spencer S K, Randle W, Kyle P B, & Shaffery J Hypertension, Anxiety, and Blood-Brain Barrier Permeability Are Increased in Postpartum Severe Preeclampsia/Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome Rats. Hypertension, 72(4), 946-954. doi:10.1161/hypertensionaha.118.117702018
Lu S, Shaffery JP, Pang Y, Tien LT, Fan LW Rapid Eye Movement Sleep Homeostatic Response: A Potential Marker for Early Detection of Parkinsons Disease. J Alzheimers Dis Parkinsonism 6: 255. doi: 10.4172/2161-0460.2016
Shaffery JP, Allard JS, Manaye K, and Roffwarg, HP Selective Rapid Eye Movement Sleep Deprivation Affects Cell Size and Number in Kitten Locus Coeruleus Front. Neur., 15 May 2012 | doi: 10.3389/fneur.2012.000692012
J.P. Shaffery, J.S. Allard, K. Manaye, H.P. Roffwarg Selective Rapid Eye Movement Sleep Deprivation Affects Cell Size and Number in Kitten Locus Coeruleus. Front. Neur., 15 May 2012;/doi: 10.3389/fneur.2012.000692012
J.P. Shaffery, J. Lopez, G. Bissette, H.P. Roffwarg Brain-derived neurotrophic factor (BDNF) reverses the effects of rapid eye movement sleep deprivation (REMSD) on developmentally regulated, long-term potentiation (LTP) in visual cortex slices. Neurosci. Lett., 2012; 512(1):84-882012
K L Wallace, J Lopez, J P Shaffery, I A Paul, W A Bennett Interleukin-10/Ceftriaxone prevents E.Coli-induced delays in sensorimotor task learning and spatial memory in neonatal and adult Sprague Dawley rats. Brain Research Bulletin. 2010; 15;81(1):141-8.2010
Lopez J, Roffwarg HP, Dreher A, Bissette G, Karolewicz B, Shaffery JP REM sleep deprivation decreases LTP stability and affects some glutamatergic signaling proteins during hippocampal development. Neuroscience 2008;153:44-53.2008
Allard JS, Tizabi Y, Shaffery JP, Manaye K Effects of rapid eye movement sleep deprivation on hypocretin neurons in the hypothalamus of a rat model of depression Neuropeptides 41:329-3372007
Shaffery JP, Lopez J, Bissette G, Roffwarg HP Rapid eye movement sleep deprivation increases cortical excitability in post-critical period, adolescent rats alters the balance between inhibitory and excitatory mechanisms in visual cortex. Neurosci Lett 2006;393:131-135.2006
Shaffery JP, Lopez J, Bissette G, Roffwarg HP Rapid eye movement sleep deprivation revives a form of developmentally regulated synaptic plasticity in the visual cortex of post-critical period rats. Neurosci Lett 2006;391:96-101.2006
Allard JS, Tizabi Y, Shaffery JP, Trouth CO, Manaye K. Stereological analysis of the hypothalamic hypocretin/orexin neurons in an animal model of depression. Neuropeptides 2004;38(5):311-5.2004
Shaffery JP, Roffwarg HP Rapid eye movement sleep (REMS) deprivation does not "rescue" a developmentally regulated long-term potentiation (LTP) in ca cortex of mature rats. Neurosci Lett 2003;342(3):196-200.2003
Marks GA, Shaffery JP, Speciale SG, Birabil CG Enhancement of rapid eye movement sleep in the rat by actions at A1 and A2a adenosine receptor subtypes with a differential sensitivity to atropine. Neuroscience 2003;116 (3):913-20.2003
J.P.Shaffery, R. Armitage, R. Hoffman The Neurobiology of Depression: Perspectives from Animal and Human Sleep Studies The Neuroscientist 9(1):82-98.2003
Shaffery JP, Sinton CM, Roffwarg HP, Bissette G, Marks GA REM sleep deprivation (RD) regulates long-term potentiation (LTP) in visual cortex of young rats. Neuroscience 2002;110:431-43.2002
D. Hogan, H.P. Roffwarg, and J.P. Shaffery Effects of One Week of Rapid Eye-Movement Sleep Deprivation on Parvalbumin and Calbindin Immunoreactive Neurons in Central Visual Pathways of Kittens Journal of Sleep Research.2001;10:285-296.2001
Shaffery JP, Roffwarg HP, Speciale SG, Marks GA PGO-wave suppression amplifies LGN cell-size changes in monocularly deprived kittens. Dev Brain Res 1999;114(1):109-119.1999
Marks GA, Shaffery JP, Roffwarg HP Neuronal activity in the lateral geniculate nucleus associated with ponto-geniculo-occipital waves lacks lamina specificity. Brain Res 1999;815:21-8.1999
Shaffery JP, Oksenberg A, Marks GA, Speciale SG, Mihailoff G, Roffwarg HP REM Sleep deprivation in monocularly occluded kittens reduces the size of cells in the LGN monocular segment. Sleep 1998;21(8):837-45.1998
Oksenberg A, Shaffery JP, Marks GA, Speciale SP, Mihailoff G, Roffwarg HP Rapid eye movement sleep deprivation amplifies LGN cell-size disparity induced by monocular deprivation in kittens. Dev Brain Res 1996;97(1):51-61.1996
Marks GA, Shaffery JP A preliminary study of sleep in the ferret, Mustela putorius furo: a carnivore with an extremely high proportion of REM sleep. Sleep 1996;19(2):83-93.1996
G.A. Marks, J.P. Shaffery, A. Oksenberg, S.G. Speciale, and H.P. Roffwarg A Functional Role for REM Sleep in Brain Maturation Behav Brain Res, 69:1-11.1995
J.P. Shaffery, N.J. Ball, and C.J. Amlaner, Jr. Daytime Sleep in Herring Gulls: A Time-Budget Manipulation. Animal Behaviour, 33:566-572.1985
N.J. Ball, Shaffery J.P., C.J. Amlaner, Jr. Sleeping Gulls and Predator Avoidance. Animal Behaviour 1984;32:1253-1266.1984
J.P.Shaffery comments on Dumoulin Bridi et al. Science Advances 03 Jul 2015:Vol. 1, no. 6,
e1500105 DOI: 10.1126/sciadv.1500105) as reported in: http://www.biosciencetechnology.com/articles/2015/07/disrupted-rem-sleep-can-rewire-young-brains
2015
J.P. Shaffery, J. Lopez and H.P. Roffwarg Enhanced Cortical Synaptic Plasticity in Post Critical Period (CP) Rats After Rapid Eye
Movement Sleep Deprivation (REMSD).
Society for Neuroscience Press Book, 2003
2003
J. Lopez, J.P. Shaffery and H.P. Roffwarg Rapid Eye Movement Sleep Deprivation (REMSD) Increases the Likelihood that Low-
Frequency Stimulation (LFS) Induces Cortical Long-Term Potentiation (LTP) in Post-Critical Period (CP), pre-adult rats
Society for Neuroscience Press Book, 2003
2003
J. P. Shaffery Lab Reports: The Animal Sleep Laboratory, University of Mississippi 2001 Sleep Research Society Bulletin. 7(1): 19-20.2001
J.P. Shaffery and H.P. Roffwarg Rapid eye-movement sleep deprivation regulates long-term potentiation in visual cortex of
young rats.
Society for Neuroscience Press Book, 1998
1998

Abstracts

C. Stewart, H.P. Roffwarg, and J.P. Shaffery Early Life REM Sleep-Deprivation Affects Synaptic Plasticity and mTOR Signaling in Hippocampus of Adult Rats Sleep Regulation & Function, Gordon Research Conference, Hotel Galvez, Galveston, TX, Mar, 13-18.2016
A. J. Bhatt, H. Zhu, J. Shen, A. M. Kaizaki, L.-T. Tien, Y. Pang, J. P. Shaffery, S. Tanaka, S. Numazawa, L.-W. Fan Celecoxib ameliorates neonatal lipopolysaccharide-induced long-lasting brain dopaminergic neuronal injury and improves neurobehavioral performance in adult rats Pediatric Academic Societies (PAS), 2015 Annual Meeting, San Diego, CA, USA, April 25-28, 20152015
Shaffery JP, Roffwarg HP Early Life REM Sleep-Deprivation has Sexually Dimorphic Effects on Hippocampal Synaptic Plasticity in Adult Rats. Sleep 38 (Supp) A17:462015
J.P. Shaffery and H.P. Roffwarg Early-Life REM Sleep Deprivation has Sexually Dimorphic Effects on Hippocampal Synaptic Plasticity in Adult Rats, Sleep Regulation & Function Gordon Research Conference, Hotel Galvez, Galveston, TX, Mar, 13-16.2014
D. Kay, C. Stewart, J.P. Shaffery and H.P. Roffwarg Early-Life REM Sleep Deprivation Affects SWS Power in Young Adult Rats Sleep, 36 (Supp), A20:442013
G. Dembla, J.P. Shaffery and H.P. Roffwarg The Effect of Different Lighting Schedules on the Sleep of the Laboratory Rat Sleep, 36 (Supp), A64:1702013
J.P. Shaffery, M.C. Austin, D. Goswami, P. Sanapureddy, R. Armitage, H.P. Roffwarg Early-Life REM Sleep Deprivation affects mRNA Expression in Frontal Cortex in Young Adult Rats, Rats Sleep 35 (Supp), A26:42012
J.P. Shaffery, D. Goswami, P. Sanapureddy, I.A. Paul, M.C Austin, R, Armitage, H.P. Roffwarg Early-Life REM Deprivation Reduces mRNA, Hippocampal Synaptic Plasticity and Delta EEG, but increase Spindle Frequency in SWS in Young Adult Rats. SE Regional IDeA Meeting, New Orleans, LA2011
J.P. Shaffery, I.A. Paul, P. Goswami, P. Sanapureddy, M.C. Austin, R. Armitage, H.P. Roffwarg Early-Life REM Sleep Deprivation Reduces mRNA, Hippocampal Synaptic Plasticity and SWS Spindle and Theta Frequencies in Young Adult Rats SLEEP 34 (Supp), A65:01452011
J.P. Shaffery, I.A. Paul, H.P. Roffwarg REM Sleep deprivation early in the critical period of brain maturation increases anxiety-like behavior in adolescents and reduces synaptic plasticity in hippocampus in adults. Program No. 300.11, Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience2010
J.P. Shaffery, H.P. Roffwarg Early Life REM Sleep Disturbance Affects Hippocampal Synaptic Plasticity in Young Adult Rats SLEEP, 33 (Supp), A62:01792010
J.P.Shaffery and H.P. Roffwarg Eszopiclone affects sleep in sleep-disturbed rats: A preliminary report Program No. 276.10, Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience.2009
Shaffery JP, Roffwarg, HP Sleep patterns in sleep-disturbed long evans rats treated with eszopiclone: A preliminary report. SLEEP, 32 (Supp), A287:08782009
J.P. Shaffery Effects of eszopiclone (ESZ) and/or fluoxetine (FLX) on hippocampal neurogenesis in sleep-deprived (SD) rats: Progress report", Oral presentation. Sepracor Scientific Research Forum, Salt Lake City, UT, October 23 to 25, 20082008
J.P. Shaffery and H.P. Roffwarg Rapid eye movement sleep deprivation reduces relative inhibition in the middle layer of primary visual cortex. Program No. 127.1. Washington, DC: Society for Neuroscience2008
J.P. Shaffery, H.P. Roffwarg REMS Deprivation May Reduce Inhibitory Tone in Layer Four to Delay Maturation of Visual Cortex. Sleep, 31 (Supp), A32-00982008
J. Shaffery, J. Allard, K.Manaye, H. Roffwarg Anatomical stress measures are not correlated with reductions in size of locus coeruleus neurons found after REM sleep deprivation Sleep, 30 (Supp), A26:00782007
J. Shaffery, J. Lopez, H.P. Roffwarg REMSD may extend the visual cortical critical period by blocking maturation of inhibitory mechanisms in the middle layer Sleep, 30 (Supp), A7:00202007
J.P. Shaffery, J. Allard, K. Manaye, H.P. Roffwarg Anatomical stress is not correlated with reduction in size of locus coeruleus neurons after REM sleep deprivation. Program No. 736.23. Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience2007
K.L. Wallace, J. Lopez, J.P. Shaffery, I.A. Paul, W.A. Bennett Il-10/Ceftriaxone treatment of bacterial intrauterine infections prevents IL-1Beta induced memory impairment. Program No. 935.20, Bastract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience2007
J. Lopez, H.P. Roffwarg, J.P. Shaffery Rapid eye movement sleep (REMS) is an endogenous source of activity contributing to hippocampal neural circuit formation and stabilization. Program No. 130.14. Abstract Viewer/Itinerary Planner, Washington, DC: Society of Neuroscience2007
J. Lopez, A. Dreher, H.P. Roffwarg, J.p. Shaffery Influence of rapid eye movement sleep deprivation (REMSD) on hippocampal maturation. Slep, 29 (Supp), A38-00082006
J.P. Shaffery, J. Lopez, G. Bissette, H.P. Roffwarg Effects in Kittens of Rapid Eye Movement Sleep Deprivation on Synaptic Plasticity Induced by Monocular Deprivation Are Not Mediated by Stress. Sleep, 28 (Supp), A242005
J. Lopez, A. Dreher, L.S. Spencer, H.P. Roffwarg, J.P. Shaffery Influence of rapid eye movement sleep deprivation (REMSD) on hippocampal maturation. Program No. 62.14, Abstract Viewer/Itinarary Planner, Washington, DC" Society for Neuroscience2005
J.P. Shaffery, J. Lopez, G. Bissette, H.P. Roffwarg REM sleep effects on visual cortical synaptic plasticity in critical period kittens are not determined by stress. Program No. 62.13, Abstract Viewer/Itinerary Planner, Washington, DC: Society for Neuroscience2005
J.P. Shaffery, J. Lopez, H.P. Roffwarg Cortical long term depression (LTD): Effects of rapid eye movement sleep (REMS)- suppression and monocular deprivation (MD) in critical period kittens. Program No. 77.10, Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience2004
J.P. Shaffery, J. Lopez, H.P. Roffwarg Infusion of Brain Derived Neurotropin Factor (BDNF) into Visual Cortex of Juvenile Rats Reverses of Effects of REM Sleep Deprivation (REMSD) on a Form of Developmentally Regulated Synaptic Plasticity. Sleep, 27 (Supp): A342004
S. Regunathan, F. Arcioglu, J.P. Shaffery, J. Lopez Neurobiological role of Agmatine in stress response. Biological Psychiatry, 55:210S2004
J. Allard, Y. Tizabi, J.P. Shaffery, C.O. Trouth, K.f. Manaye Sterological analysis of the hypothalamic hypocretin neurons in an animal model of depression. Program No. 570.18, Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience2004
J.P. Shaffery, J. Lopez, H.P. Roffwarg Enhanced Cortical Synaptic Plasticity in Post-Critical Period Rats After REMS Deprivation. Sleep, 26 (Abs. Supp): A12003
J.P. Shaffery, J. Lopez, H.P. Roffwarg Enhanced Cortical Synaptic Plasticity in Post-Critical Period (CP) Rats After Rapid Eye Movement Sleep Deprivation (REMSD). Program No. 56.7, Abstract Viewer/Itinerary Planner, Washington, DC: Society for Neuroscience2003
J. Lopez, J.P. Shaffery, H.P. Roffwarg Rapid Eye Movement Sleep Deprivation (REMSD) Increased the likelihood that Low-Frequency Stimulation (LFS) induces Cortical Long-Term Potentiation (LTP) in Post-Critical Period (CP), pre adult rats. Program No. 56.1, Abstract Viewer/Itinerary Planner, Washington, DC: Society for Neuroscience2003
J.P. Shaffery, H.P. Roffwarg Effects of MK-801 on Lateral Geniculae Nucleus Cell-size Ratios in Monocularly Occluded Kittens. Soc. Neurosci, Abs.: 28:820.12002
J.P. Shaffery, J.S. Allard, d. Hogan, H.P. Roffwarg, K. Manaye Rapid Eye-movement Sleep (REMS) Deprived Kittens Have Increased EEG Delta Activity and Reduced Levels of Tyrosine Hydroxylase (TH) Immunoreactivity in Locus Ceruleus (LC). Sleep, 25 (supp): A1092002
J.P. Shaffery, J. Johnson, H.P. Roffwarg Rapid Eye Movement Sleep (REMS) Deprivation Does Not "Rescue" a Developmentally Regulated Long-term Potentiation (LTP) in Visual Cortex of Mature Rats. Soc. Neurosci, Abstr:27:524.102001
J.S. Allard, D. Hogan, J. Johnson, H.P. Roffwarg, K. Manaye, C.O. Trouth, J.P. Shaffery Rapid Eye-movement Sleep (REMS) Deprivation in Kittens Affects Tyrosine Hydroxylase (TH) Immunoreactive Cell Density in Locus Coeruleus (LC). Soc. Neurosci. Abstract 27:524.172001
J.P. Shaffery, J. Joyce, H.P. Roffwarg Suppression of Rapid Eye-Movement Sleep in Older Rats Does Not "Rescue" the Age-Related Loss of a Developmentally Regulated Form of Synaptic Plasticity. Sleep, 24 (Supp). A140-1412001
J.P. Shaffery, D. Hogan, H.P. Roffwarg Daily Sleep Quantities in Kittens Receiving Low Doses of MK-801 by Osmotic Minipump Infusion (IP) for One Week. Sleep (Supp) 23(2):A1372000
J.P. Shaffery, D. Hogan, H.P. Roffwarg Sleep in Critical Period Kittens Is Differentially Affected by Two Low Doses of MK-801. Soc. Neurosci. Abstr.,26:1072000
J.P. Shaffery, S.G. Speciale, H.P. Roffwarg, G.A. Marks Effects of REM Sleep Deprivation on Brain Excitability in Wake Are Not Mediated by Alterations in Thalamic Neurons. Soc. Neurosci, Abstr. 25 (2):16141999
J.P. Shaffery, C.M. Sinton, T. Fitch, H.P. Roffwarg, G.A. Marks REM Sleep Deprivation (RD) Regulates Long-Term Potentiation (LTP) in Visual Cortex of Young Rats. Sleep, (Supp) 22(1):B159.A1999
D. Hogan, H.P. Roffwarg, J.P. Shaffery Sleep Architecture Changes in Kittens Deprived of Rapid Eye-Movement Sleep (Rems) by Computer-Controlled Mechanical Shaking. Soc. Neurosci. Abstr., 25 (2):16141999
D.Hogan, H.P. Roffwarg, Z. Li, J.P. Shaffery Calcium-binding Protein Immunoreactive Neurons in Central Visual Pathways are Changed by One Week of Rapid Eye-Movement Sleep (REMS) Deprivation in Kittens. Soc Neurosci, Abstr. 24(2):14301998
J.P. Shaffery, D. Hogan, I.A. Paul, Z. Li, H.P. Roffwarg Effects of REM Sleep Deprivation on Radioligand Binding to GABAA and NMDA Receptors in Frontal and Visual Cortex of Immature Rats. Sleep Res. 21 (Supp):361998
G.Bissette, R. Frederic, H.P. Roffwarg, J.P. Shaffery Neuropeptide Alterations in REM Sleep Deprived Rat Brain Regions. Soc Neurosci. Abstr. 24(2):14301998
J.P. Shaffery. C.M. Sinton, H.P. Roffwarg, G.A. Marks REM Sleep Deprivation (REMSD) Regulates Long-Term Potentiation in Visual Cortex of Young Rats. Soc. Neurosci. Abstr. 24(2):14311998
M. Kimura, S.M. McCann, G.A. Marks, J.P. Shaffery, T. Kodama, S.O. Zhang, S. Inoue A Novel Somnogenic Cytokine: Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF). Soc. Neurosci. Abstr. 23:7921997
J.P. Shaffery, G.A. Marks, S.G. Speciale, H.P. Roffwarg LGN Cell-size Changes Following PGO-wave Elimination in Monocularly Deprived (MD) Kittens. Sleep Res. 26:671997
D. Hogan, J.P. Shaffery, I.A. Paul, A. Li, H.P. Roffwarg Rapid Eye-Movement Sleep (REMS) Deprivation Reduces (3H)Flunitrazepam (Flu) Binding to GABAA Receptors in Frontal Cortex of Immature Rats. Soc. Neurosci. Abstr.23:3131997
J.P. Shaffery, D.Hogan, I.A. Paul, S. Li, H.P. Roffwarg Rapid Eye-Movement Sleep (REMS) Deprivation Doesn Not Affect (3H)MK801 Binding to NMDA Receptors in Frontal Cortex of Immature Rats. Soc Neurosci. Abstr.,23:3131997
G.A. Marks, and J.P.Shaffery A Preliminary Study of Sleep in the Ferret, Mustela putorius furo: A Carnivore With an Extremely High Proportion of REM Sleep Sleep, 19(2):83-931996
J.P. Shaffery, G.A. Marks, S.G. Speciale, H.P. Roffwarg Bilateral, Pontomesencephalic Lesions Increase Monocular Deprivation (MD)-Induced, Plastic Changes In Lateral Geniculate Nucleus (LGN) Cells. Soc. Neurosci. Abst.22:20.01996
J.P. Shaffery, T. Fitch, S.G. Speciale, H.P. Roffwarg, r. Armitage, G. A. Marks The Effects of Bilateral Mesencephalic Lesions That Eliminate PGO-Waves on the Cortical ECoG. Sleep Res. 1996;25:261996
J.P. Shaffery, T. Fitch, S.G. Speciale, H.P. Roffwarg, R. Armitage, G.A. Marks Sleep Architecture in Kittens After Bilateral Mesencephalic Lesions that Eliminate Ponto-Geniculo-Occipital (PGO) Waves in the Lateral Geniculate Nucleus (LGN). Soc Neurosci.Abst. 21:379.71995
J.P. Shaffery, T. Fitch, S.G. Speciale, H.P. Roffwarg, R. Armitage, G.A. Marks Sleep Micro-Architecture Following Bilateral Mesencephalic Lesions that Eliminate PGO-Waves. Sleep Res. 24A:611995
J.P. Shaffery, G.A. Marks Low Doses of Para-Chlorophenylalaine Induces a Partial Insomnia in the Ferret by Reducing REM Sleep Amounts. Soc. Neurosci. Abstr., 20:70.71994
J.P. Shaffery, G.A. Marks REM sleep in the Ferret, II: The Effects of Lighting Schedule. Sleep Res., 23:1771994
J.P. Shaffery, A. Oksenberg, G.A Marks, S.G. Speciale, H.P. Roffwarg REM Sleep Deprivation (REMS DEP) Reduces Cell-size in the Visually Deprived Monocular Segment of Kitten LGN. Soc. Neurosci. Abstr., 19:370.51993
J.P. Shaffery, A. Oksenbert, G.A Marks, S.G. Speciale, H.P. Roffwarg REM Sleep Deprivation Produces Cell-size Reduction in the Visually Deprived Monocular Segment of Kitten LGN. Sleep Res., 22:631993
G. A. Marks, J.P. Shaffery, H.P. Roffwarg Retinal and PGO-related Thalamic Afference Differ in Terms of LGN Lamina Specificity. Sleep Res., 22:691993
J.P. Shaffery, G.A. Marks, S.G. Speciale, H.P, Roffwarg Computer-Aided Sleep-Staging in Young Kittens. Sleep Res., 21:351992
J.P. Shaffery, H.P. Roffwarg, G.A. Marks Facilitation of LGN Unit Activity Associated with the Non-Retinal Ponto-Geniculo-Occipital (PGO) Wave Lacks Lamina Specificity. Soc. Neurosci. Abstr.,18:554.41992
G.A. Marks, J.P. Shaffery, S.G. Speciale, H.P. Roffwarg Investigating the Mechanisms of Auditory Ponto-Geniculo-Occipital Waves in the Cat. Soc. Neurosci. Abs., 1991;17:34141991
J.P. Shaffery, G.A. Marks, S.G. Speciale, H.P. Roffwarg PGO-Wave Suppression During REM-Sleep in Moncularly Deprived Kittens Increases LGN Relay Cell Plasticity. Soc. Neurosci. Abstr., 17:3491991
J.P. Shaffery, G.A. Marks S.G. Speciale, H.P. Roffwarg The Ontogenetic Hypothesis of REM-Sleep, Ponto-Geniculo-Occipital (PGO) Waves and Developmental Plasticity: A Preliminary Report. Sleep Res., 20A:2161991
J.P. Shaffery, G.A. Marks, S.G. Speciale, H.P. Roffwarg An Autoradiographic Study of the Effects of REM-Sleep on Ocular Dominance Patch Formation in Visually Deprived Kittens. Soc. Neurosci. Abstr., 16:476.181990
R. Armitage, J.P.. Shaffery, G.A. Marks, S.G. Sepciale, H.P. Roffwarg Digital Period Analysis of Sleep EEG in Young Kittens: A Preliminary report. Sleep Res., 19:1041990
J.P. Shaffery, G.A. Marks, S.G. Speciale, H.P. Roffwarg REM-Sleep Deprivation on a Vibrating Platform: Automating a Standard Technique. Sleep Res., 19:1101990
J.P. Shaffery, G.A. Marks, S.G. Speciale, H.P. Roffwarg REM-Sleep in the Ferret. Sleep Res., 19:1121990
J.P. Shaffery, G. Buchanan, D.F. Schmidt, N.J. Ball, C.J. Amlaner, Jr. Sleep in the 1-Day Old Mallard. Sleep Res., 18:2911988
J.P. Shaffery, N.J. Ball, M.R. Opp, C.J. Amlaner, Jr Eye-closure Durations in Adult and Nearly Fledged Glaucous-winged Gulls (Larus glaucescens). Sleep Res., 16:1871987
N.J. Ball, J.P. Shaffery, M.R. Opp, C.J. Amlaner, Jr Towards an Understanding of the Function of Natural Sleep. Sleep Res., 16:1911987
N.J. Ball, J.P. Shaffery, M.R. Opp, R.L. Carter, C.J. Amlaner, Jr Asyncohronous Eye Closure of Birds. Sleep Res.,14:871986
J.P. Shaffery, C.J Amlaner, Jr, N.J. Ball, M.R. Opp Ethological and Ecological Correlates of Sleep in Free-ranging glaucous-Winged Gulls (Larus glacescens). Sleep Res., 14:1031986
J.P. Shaffery, N.J. Ball, C.J. Amlaner, Jr, M.R. Opp Ethological Sleep Studies in Glaucous-Winged Gulls Larus glaucescens. Sleep Res., 15:611986

Dissertation

J.P. Shaffery. Foraging Development in the Herring Gull (Larus argentatus). Published D. Phil. Thesis. Oxford University, U.K.1984

Book Chapter

Shaffery JP Sleep and Brain Maturation Hans C. Dringenberg, editor, Handbook of Behavioral Neuroscience, Vol. 30, Amsterdam: Academic Press, 2019, pp. 413-4242019
Shaffery JP, & Roffwarg HP The Ontogenetic Hypothesis of Rapid Eye Movement Sleep Function Revisited Current Advances in Sleep Biology (ed. Frank, M.G.) 177-216 (Nova Science Publishers, New York, 2009)2009
Shaffery JP Radio-Telemetry of Habitat Use and Activity Patterns in Northern Bobwhite in Northwestern Arkansas, pp. 145-150, In: Biotelemetry X, C.J. Amlaner, Jr., (Ed) University of Arkansas Press, Fayetteville1989
D.F. Schmidt, J.P. Shaffery, N.J. Ball, D. Loenneke, and C.J. Amlaner, Jr. Electrophysiological Sleep Characteristics in Bobwhite Quail. Biotelemetry X, 1989;pp. 339-344,University of Arkansas Press, Fayetteville.1989
Ball, N.J., Amlaner, Jr, C.J., Shaffery, J.P. and Opp, M.R. Asynchronous Eye-closure and Unihemispheric Quiet Sleep of Birds. p. 127-128 In: Sleep '86, W.P. Koella, H. Schulz, F. Obal and P. Visser (Eds), Gustav Fischer: Stuttgart1987
Shaffery, J.P. Ball, N.J., Opp, M.R. and Amlaner, C.J. Jr Sleep Ethology in Glaucous-winged Gulls (Larus glaucescens). p. 229-231. In: Sleep '86, W.P. Koella, H. Schulz, F. Obal and P. Visser (Eds)Gustav Fischer: Stuttgart.1987

Presentations

State/Local Invited Seminars/Lectures, Center for Psychiatric Neuroscience Animal Behavior Core: Testing for Learning and Memory, Neuroscience Brown Bag Seminar Series, University of Mississippi Medical Center School of Pharmacy09/2016
State/Local Invited Seminars/Lectures, Early-Life REM Sleep Deprivation Programs Alterations in Hippocampal Synaptic Plasticity, mRNA, Protein and Sleep Architecture in Young, Adult Rats, Center for Developmental Disorders Research Seminar Series, UMMC02/2016
State/Local Invited Seminars/Lectures, Early-Life REM Sleep Deprivation Programs alterations in mRNA, Hippocampal Synaptic Plasticity and Sleep Architecture in Young Adult Rats, Department of Neurobiology and Anatomical Science Seminar Series., UMMC10/2014
National and International Invited Seminars/Lectures, Early-Life REM Sleep Deprivation Programs alterations in mRNA, Hippocampal Synaptic Plasticity and Sleep Architecture in Young Adult Rats: Part I., NIMH, Sleep and Neurodevelopment Workshop, Bethesda, MD09/2014
National and International Invited Seminars/Lectures, Early-Life REM Sleep Deprivation Programs alterations in mRNA, Hippocampal Synaptic Plasticity and Sleep Architecture in Young Adult Rats: Part II., NIH Sleep and Neurodevelopmental Workshop, Bethesda, MD09/2014
National and International Invited Seminars/Lectures, Effects of eszopiclone (ESZ) and/or fluoxetine (FLX) on hippocampal neurogenesis in sleep-deprived (SD) rats: Progress report, Sepracor Scientific Research Forum, Salt Lake City, UT10/2008
National and International Invited Seminars/Lectures, REM Sleep and Developmental Synaptic Plasticity: Probing Brain Maturation with REMS Deprivation, East Virginia Medical School Physiological Sciences Departmental Seminar Series, Norfolk, VA, East Virginia Medical School04/2006
National and International Invited Seminars/Lectures, REM Sleep Function: Probing the Postnatal Critical Period of Brain Maturation with REMS Deprivation, presented at Department of Physiology and Biophysics Seminar Series in Physiology, Howard University School of Medicine, Department of Physiology and Biophysics Seminar Series in Physiology, Howard University School of Medicine, Washington, D.C.04/2006
National and International Invited Seminars/Lectures, REM Sleep and Developmental Synaptic Plasticity. Winter Conference: Current Issues in Developmental Psychobiology, Developmental Psychobiology, Panama City, Panama02/2006
Invited Symposia, REM Sleep and Developmental Synaptic Plasticity. MS Chapter of the Society for Neuroscience. First Tuesday Seminar, University of Mississippi Medical Center, Jackson, MS02/2006
State/Local Invited Seminars/Lectures, REM Sleep and Developmental Synaptic Plasticity: Probing the Critical Period with REMS Deprivation. Presented at Departmental Research Day Symposium on Sleep, University of Mississippi Medical Center, Jackson, MS03/2004
State/Local Invited Seminars/Lectures, REM Sleep and Developmental Plasticity: Extending the Critical Period, University of Mississippi Medical Center Mississippi Chapter of Society for Neuroscience, Jackson, MS12/2003
National and International Invited Seminars/Lectures, Role of Rapid Eye Movement Sleep in the Developmental Synaptic Plasticity in Rat Visual Cortex, Annual Meeting of the Association of Professional Sleep Societies (APSS), Seattle WA06/2002
National and International Invited Seminars/Lectures, Studies of the Relationship of Rapid Eye Movement (REM) Sleep to Developmental Plasticity and Maturation in the Mammalian Brain., University of Arkansas Medical School, Little Rock, AR04/2001
National and International Invited Seminars/Lectures, The Role of Rapid Eye-Movement Sleep in Synaptic Plasticity During Brain Maturation. Department of Physiology and Biophysics Seminar Series in Physiology, Howard University School of Medicine, Washington, D.C2001
National and International Invited Seminars/Lectures, A Role for Rapid Eye Movement Sleep in Modifying Synaptic Plasticity in Visual Cortex, Congress for World Federation of Sleep Research Societies, Dresden, Germany10/1999
State/Local Invited Seminars/Lectures, Testing the Ontogenetic Hypothesis of Rapid Eye-movement Sleep Function in Brain Development: in vivo and in vitro Studies., University of Mississippi Medical Center,Department of Psychiatry and Human Behavior, Grand Rounds, Jackson, MS09/1999
National and International Invited Seminars/Lectures, REM sleep deprivation (RD) regulates long-term potentiation (LTP) in visual cortex of young rats, Associated Professional Sleep Societies, Orlando, FL06/1999
State/Local Invited Seminars/Lectures, REM Sleep Deprivation (RD) Regulates Long-Term Potentiation (LTP) in Visual Cortex of Young Rats. DNBR Neurobiology & Behavior Workshop, University of Mississippi Medical Center, Jackson, MS06/1999
State/Local Invited Seminars/Lectures, The Role of REM Sleep in CNS Development, Mississippi Chapter of Society for Neuroscience (UMMC), Jackson, MS06/1998
State/Local Invited Seminars/Lectures, The Role of REM Sleep in Development, University of Mississippi Medical Center, Physiology Department Seminar Series, Jackson, MS06/1997

Honors, Awards, and Recognition

Gold Award for Excellence in Research Award, University of Mississippi Medical Center
Silver Award for Excellence in Research Award, University of Mississippi Medical Center
Winner of Departmental Research Day Big Idea Incentive Grant, University of Mississippi Medical Center

Professional Membership and Service

MS Chapter of the Society for Neuroscience, Officer, Treasurer, Treasurer2008 - Present
Sleep Research Society, Member1998 - Present
MS Local Chapter of the Society for Neuroscience, Officer, President/Elect/Past, President1997 - 1999
MS Local Chapter of the Society for Neuroscience, Member1995 - Present
Society for Neuroscience, Member1989 - 2012
World Sleep Research Society1989 - Present

Committee Service

Sleep Research Society, Pipeline Development Committee, Chair2019 - 2022
Sleep Research Society, Pipeline Committee, Member2016 - 2019
Graduate Program in Neuroscience Curriculum Subcommittee, Member2015 - Present
Graduate Program in Neuroscience, Member2015 - Present
Sleep Research Society Educational Committee, Chair2010 - 2014
Institutional Animal Care and Use Committee, Member2008 - Present
Sleep Research Society Educational Committee, Member2008 - 2010
Departmental Performance Improvement Committee, Member2004 - 2007
COBRE-funded Center for Psychiatric Neuroscience Executive Committee, Member2003 - Present
Departmental Grand Rounds Committee, Member2002 - 2004
Ad Hoc Committee on Scientific Network Computing, Member2002 - 2010
Departmental Computer Committee, Member2001 - 2004
Department of Psychiatry, Division of Neurobiology and Behavioral Research Safety Officer, Member2001 - Present
Information Systems Strategic Planning Committee, Education Subcommittee, Clinical Sciences Working Group, Member2000 - 2001
Dean of Research - Ad Hoc Committee on Scientific Network Computing, Member1999 - 1999
Mississippi Chapter of the Society for Neuroscience, President1997 - Present

Community Service

Committee to organize Brain Awareness Week activities, Chair2009 - Present
Committee to organize Brain Awareness Week activities, Chair2007 - Present
Elementary Science Fair, Judge10/1999 - 10/1999
Jackson Elementary Science Fair, Judge09/1989 - 09/1989

Other Service

Department of Defense Congressionally Directed Medical Research Programs (CDMRP), Peer Reviewed Medical Research Program, 10 grant applications reviewed08/2016 - 08/2016
Department of Defense Congressionally Directed Medical Research Programs Focused Program Award Sleep Disorder (FP-SD); FY-15 Peer Reviewed Medicine Program (PRMRP), 1 Program project grant reviewed, consisting of 4 separate projects12/2015 - 12/2015
Brain Sciences, 1 manuscript reviewed11/2015 - Present
Journal of Neurophysiology, 1 manuscript reviewed10/2015 - Present
NIH/NIGMS Support of Competitive Research (SCORE), 2 grant applications reviewed10/2015 - 10/2015
Annals of Medicine, 1 manuscript reviewed08/2015 - Present
Sleep Science, 3 manuscripts reviewed05/2015 - Present
NIH/Neuroendocrine, Neuroimmunology, Rhythms and Sleep Initial Review Group, 10 grant applications reviewed02/2015 - 02/2015
NIH/Neuroendocrine, Neuroimmunology, Rhythms and Sleep Initial Review Group, 10 grant applications reviewed06/2014 - 06/2014
NIH/Neuroendocrine, Neuroimmunology, Rhythms and Sleep Initial Review Group, 9 grant applications reviewed02/2014 - 02/2014
Journal of Clinical Sleep Medicine, 1 manuscript reviewed02/2014 - Present
NIH/Neuroendocrine, Neuroimmunology, Rhythms and Sleep Initial Review Group, 7 grant applications reviewed05/2013 - 05/2013
Neurobiology of Learning and Memory, 2 manuscripts reviewed01/2013 - Present
BMC Neuroscience, 1 manuscript reviewed12/2012 - Present
Brain Research Bulletin, 1 manuscript reviewed09/2012 - Present
Sleep Medicine Reviews, 1 manuscript reviewed05/2012 - Present
Frontiers in Sleep and Chronobiology, 1 manuscript reviewed01/2012 - Present
Frontiers in Neurology, 1 manuscript reviewed01/2012 - Present
NIH/Molecular, Cellular and Developmental Neurosciences Special Interest Panel, 1 grant application reviewed12/2011 - 12/2011
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 1 manuscript reviewed10/2011 - Present
Current Biology, 1 manuscript reviewed10/2011 - Present
NIH/ZRG1 AARR-F (52)-R Initial Review Group, 4 grant applications reviewed10/2011 - 10/2011
NIH/ZRG1 AARR-F (52)-R Initial Review Group, 9 grant applications reviewed05/2011 - 05/2011
NIH/ZRG1 AARR-F (52)-R Initial Review Group, 4 grant applications reviewed02/2011 - 02/2011
Physiology & Behavior, 2 manuscripts reviewed01/2011 - Present
Neuroscience Letters, 3 manuscripts reviewed07/2010 - Present
Behavioral and Brain Functions, 1 manuscript reviewed05/2010 - Present
National Science Foundation, 1 grant application reviewed04/2010 - 04/2010
NIH/ZRG1 AARR-F (50)-R Initial Review Group, 8 applications reviewed02/2010 - 02/2010
NIH/ZRG1 AARR-F (50)-R Initial Review Group, 5 applications reviewed10/2009 - 10/2009
The Open Sleep Journal, 1 manuscript reviewed06/2009 - Present
NIH/ZRG1 AARR-F (50)-R Initial Review Group, 3 grant applications reviewed05/2009 - 05/2009
Epilepsy & Behavior, 1 manuscript reviewed08/2008 - Present
Journal of Neuroscience, 1 manuscript reviewed03/2008 - Present
Scholarpedia, 1 manuscript reviewed06/2007 - Present
Pharmacological Research, 1 manuscript reviewed10/2006 - Present
Neuroscience, 4 manuscripts reviewed09/2006 - Present
Behavioral Brain Research, 7 manuscripts reviewed07/2006 - Present
Neuroscience & Biobehavioral Reviews, 1 manuscript reviewed01/2006 - Present
Brain Research, 5 manuscripts reviewed07/2004 - Present
Journal of Sleep Research, 1 manuscript reviewed06/2004 - Present
Sleep, In the last 10 years I have reviewed over 20 research manuscripts for this journal, not counting re-reviews2004 - Present
Association of Professional Sleep Societies Annual Meetings, Abstract Reviewer for annual SLEEP meeting, 25 abstracts per year2000 - Present

Teaching Experience

NSCI710, Graduate, Course, Course Director, Experimental Design and Biostatistics in NeuroscienceSpring 2017
NSCI701, Graduate, Lecture, Lecturer, Sleep and Sleep DisordersSpring 2017
NSCI701, Graduate, Lecture, Lecturer, Experience and Refinement of Synaptic ConnectionsSpring 2017
NSCI710, Graduate, Lecture, Lecturer, Experimental Design and Biostatistics in Neuroscience: Parametric and Non-Parametric Correlations and RegressionsSpring 2017
Medicine, Small Group, co-discussant, Department of Psychiatry Behavioral Health Clinic Wrap-up SessionsSpring 2017
NSCI701, Graduate, Lab, Lab Presenter, Neurophysiological recording techniques: Voltage/Patch Clamping and extracellular recordingFall 2016
NSCI720, Graduate, Course, Course Director, Program in Neuroscience Student Journal ClubAnnual 2016 - 2017
Medicine, Small Group, Co-discussant., Psychiatry Behavioral Health Specialty Clinic Wrap Up SessionsFall 2016
NSCI701, Graduate, Lecture, Lecturer, Postsynaptic Potentials and Synaptic IntegrationFall 2016
NSCI701, Graduate, Lecture, Lecturer, Overview of Synaptic TransmissionFall 2016
NSCI701, Graduate, Course, Section Director, The SynapseFall 2016
NSCI701, Graduate, Lecture, Lecturer, Sleep NeurobiologySpring 2016
NSCI701, Graduate, Lecture, Lecturer, Experience and Refinement of Synaptic ConnectionsSpring 2016
NSCI 710, Graduate, Course, Course Director, Experimental Design and Biostatistics in NeuroscienceFall 2015
NSCI 720, Graduate, Course, Course Director, Program in Neuroscience Student Journal ClubAnnual 2015 - 2016
Medicine, Small Group, co-discussant, Psychiatry Behavioral Health Specialty Clinic Wrap Up SessionsAnnual 2015 - 2016
NSCI710, Graduate, Lecture, Lecturer, Experimental Design and Biostatistics in Neuroscience: Parametric and Non-Parametric Correlations and RegressionsFall 2015
NSCI701, Graduate, Course, Section Director, The SynapseFall 2015
NSCI701, Graduate, Lecture, Lecturer, Sleep NeurobiologySpring 2015
NSCI701, Graduate, Lecture, Lecturer, Experience and Refinement of Synaptic ConnectionsSpring 2015
NSCI701, Graduate, Lecture, Lecturer, Postsynaptic Potentials and Synaptic IntegrationFall 2015
NSCI701, Graduate, Lecture, Lecturer, Overview of Synaptic TransmissionFall 2015
NSCI701, Graduate, Lab, Lab Presenter, Neurophysiological recording techniques: Voltage/Patch Clamping and extracellular recordingFall 2015
Medicine, Lecture, Lecturer, Medical NeurobiologySpring 2014
NSCI701, Graduate, Lecture, Lecturer, Sleep NeurobiologySpring 2014
NSCI701, Graduate, Lecture, Lecturer, Experience and Refinement of Synaptic ConnectionsSpring 2014
NSCI701, Graduate, Course, Section Director, The SynapseFall 2014
NSCI701, Graduate, Lecture, Lecturer, Postsynaptic Potentials and Synaptic IntegrationFall 2014
NSCI701, Graduate, Lecture, Lecturer, Overview of Synaptic TransmissionFall 2014
NSCI701, Graduate, Lab, Lab Presenter, Neurophysiological recording techniques: Voltage/Patch Clamping and extracellular recordingFall 2014
NSCI701, Graduate, Lecture, Lecturer, Sleep NeurobiologySpring 2013
NSCI701, Graduate, Lecture, Lecturer, Experience and Refinement of Synaptic ConnectionsSpring 2013
NSCI701, Graduate, Course, Section Director, The SynapseFall 2013
NSCI701, Graduate, Lecture, Lecturer, Postsynaptic Potentials and Synaptic IntegrationFall 2013
NSCI701, Graduate, Lecture, Lecturer, Overview of Synaptic TransmissionFall 2013
NSCI 704, Graduate, Course, Lecturer, Behavioral DevelopmentSpring 2013
NSCI701, Graduate, Lecture, Course Director, Fundamentals in NeuroscienceFall 2013
NSCI701, Graduate, Lecture, Lecturer, Neurophysiology of Synaptic Plasticity a & bFall 2013
NSCI701, Graduate, Lab, Lab Presenter, Extracellular Recording in Brian SlicesFall 2013
NSCI701, Graduate, Lecture, Lecturer, Passive Electrical PropertiesFall 2013
NSCI701, Graduate, Lecture, Lecturer, Membrane PotentialsFall 2013
NSCI 701, Graduate, Lecture, Lecturer, NeuronsFall 2013
NSCI 702, Graduate, Course, Lecturer, Protein Phosphorylation/Serine Threonine and Tyrosine PhosphorylationFall 2012 - 2012
NSCI 720, Graduate, Small Group, Guest Presenter, Sleep and Memory: Functions for both sleep statesFall 2012 - 2012
NSCI 704, Graduate, Course, Lecturer, Behavioral DevelopmentSpring 2012
NSCI701, Graduate, Lecture, Course Director, Fundamentals in NeuroscienceFall 2012
NSCI701, Graduate, Lecture, Lecturer, Neurophysiology of Synaptic Plasticity a & bFall 2012
NSCI701, Graduate, Lab, Lab Presenter, Extracellular Recording in Brian SlicesFall 2012
NSCI701, Graduate, Lecture, Lecturer, Passive Electrical PropertiesFall 2012
NSCI701, Graduate, Lecture, Lecturer, Membrane PotentialsFall 2012
NSCI 701, Graduate, Lecture, Lecturer, NeuronsFall 2012
NSCI 730, Graduate, Course, Lecturer, Cellular Mechanism of Learning: Synaptic PlasticitySpring 2012
NSCI 703, Graduate, Course, Course Director, NeurophysiologyFall 2012
NSCI 703, Graduate, Course, Lecturer, Passive Electrical Properties of NeuronsFall 2012
NSCI 704, Graduate, Course, Lecturer, Behavioral DevelopmentSpring 2011 - 2013
NSCI701, Graduate, Lecture, Course Director, Fundamentals in NeuroscienceFall 2011 - 2011
NSCI 701, Graduate, Lecture, Lecturer, NeuronsFall 2011 - 2011
NSCI701, Graduate, Lecture, Lecturer, Membrane PotentialsFall 2011 - 2011
NSCI701, Graduate, Lecture, Lecturer, Passive Electrical PropertiesFall 2011 - 2011
NSCI701, Graduate, Lab, Lab Presenter, Extracellular Recording in Brian SlicesFall 2011 - 2011
NSCI701, Graduate, Lecture, Lecturer, Neurophysiology of Synaptic Plasticity a & bFall 2011 - 2011
NSCI 730, Graduate, Course, Lecturer, Cellular Mechanism of Learning: Synaptic PlasticitySpring 2011
NSCI 703, Graduate, Course, Course Director, NeurophysiologyFall 2011
NSCI 703, Graduate, Course, Lecturer, Passive Electrical Properties of NeuronsFall 2011
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2011
NSCI 730, Graduate, Course, Lecturer, Cellular Mechanism of Learning: Synaptic PlasticitySpring 2010
NSCI 703, Graduate, Course, Course Director, NeurophysiologyFall 2010
NSCI 703, Graduate, Course, Lecturer, Passive Electrical Properties of NeuronsFall 2010
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2010
NSCI 730, Graduate, Course, Lecturer, Cellular Mechanism of Learning: Synaptic PlasticitySpring 2009
NSCI 703, Graduate, Course, Course Director, NeurophysiologyFall 2009
NSCI 703, Graduate, Course, Lecturer, Passive Electrical Properties of NeuronsFall 2009
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2009
NSCI 730, Graduate, Course, Lecturer, Cellular Mechanism of Learning: Synaptic PlasticitySpring 2008 - 2011
NSCI 703, Graduate, Course, Lecturer, Passive Electrical Properties of NeuronsFall 2008 - 2011
NSCI 703, Graduate, Course, Course Director, NeurophysiologyFall 2008 - 2012
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2008
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2007
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2006
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2005
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2004
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2003
PGY-1, Medicine, Lecture, Lecturer, Residents Didactic Series: Basic Neuroscience: Basic NeurophysiologyFall 2002 - 2002
PGY-1, Medicine, Course, Lecturer, Residents Didactic Series: Basic Neuroscience: Review of NeuroanatomyFall 2002
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2002
PHARM 780, Graduate, Course, Lecturer, Neurophysiology and Neuropharmacology of SleepFall 2001 - 2011
SHRP, Lecture, Lecturer, Circadian Rhythms and Sleeping and WakingWinter 2000 - 2000
Medicine, Course, Lecturer, Attention Deficit Hyperactivity DisorderSpring 1997 - 1999
Medicine, Course, Lecturer, Neurophysiology: From Passive Membrane Properties to Action Potential GenerationFall 1997 - 1999
Graduate, Course, Lecturer, Neurophysiology and Pharmacology of SleepFall 1997 - 1999
Medicine, Lecture, Lecturer, Sleep NeurobiologyFall 1997 - 1999

Directed Student Learning

Research Advisor, UMCGS, SURE student
Advised: Amanda Blackwell
2016 - 2016
Supervised Research, Medical Student Research Program-Department of Psychiatry M1 Summer Research
Advised: Sorsha Morris
2016 - Present
Research Advisor, INBRE student
Advised: Alana Knowles
2016 - 2016
Research Advisor, BASE Pair summer intern
Advised: Micaiah Tillman
2016 - Present
Research Advisor, BASE Pair summer intern
Advised: Jose Navas
2016 - Present
Supervised Research, Base Pair High School Research Experience Program
Advised: Tyrone McDonald
2013 - 2014
Research Advisor, Early-Life REM Sleep Deprivation Affects EEG Power in Young Adult Rats
Advised: Daniel Kay
2012 - 2013
Supervised Research, Sleep in antidepressant-treated rats.
Advised: Joseph Creel
2012 - 2012
Research Advisor, Dean's Summer Research Program
Advised: Brannon Griffin
2012 - 2012
Supervised Research, Sleep in Rodents
Advised: Megan Porter
2012 - 2012
Research Advisor, COBRE-CPN-Neuroscience Summer Scholar Program
Advised: Ruigi Feng
2011 - 2011
Research Advisor, COBRE-CPN-Neuroscience Summer Scholar Program
Advised: Brannon Griffin
2010 - 2010
Dissertation Committee Member, Dysregulation of Serotonin During Early Development Alters Interhemispheric Connectivity in Rodents
Advised: Loai Alzghoul
2010 - 2012
Research Advisor, COBRE-CPN-Neuroscience Summer Scholar Program
Advised: Jenny Barnes
2009 - 2009
Dissertation Committee Chair, The effect of prenatal intrauterine infection on behavioral development: Short – and long-term consequences demonstrated in a rodent model
Advised: Kedra Wallace
2008 - 2009
Research Advisor, COBRE-CPN-Neuroscience Summer Scholar Program
Advised: Iman Abdelrahman
2008 - 2008
Supervised Research, Base Pairs Student
Advised: Theresa Raymond
2007 - 2008
Research Advisor, Functional role of rapid eye movement sleep (REMS) in brain development in young and adolescent rats
Advised: Nolan McIntyre
2007 - 2007
Research Advisor, COBRE-CPN-Neuroscience Summer Scholar Program
Advised: Lindsey Berg
2007 - 2007
Research Advisor, Effect of lighting schedules on the Sleep-Wake Behavior in the Rat
Advised: Geetika Dembla
2007 - 2009
Research Advisor, COBRE-CPN-Neuroscience Summer Scholar Program
Advised: Erin Johnson
2006 - 2006
Research Advisor, COBRE-CPN-Neuroscience Summer Scholar Program
Advised: Mark Tadros
2005 - 2005
Dissertation Committee Chair, REM sleep deprivation decreases LTP stability and affects some glutamatergic signaling proteins during hippocampal development
Advised: Jorge Lopez
2005 - 2009
Research Advisor, COBRE-CPN-Neuroscience Summer Scholar Program
Advised: Thomas Rinaldi
2004 - 2004
Supervised Research, COBRE/Center for Psychiatric Neuroscience
Advised: Sonya Jagwani
2003 - 2003
Research Advisor, Stereological Analysis of Noradrenergic and Hypocretinergic Cell Groups After Deprivation of Rapid Eye Movement Sleep
Advised: JoAnne Allard
2001 - 2005
Research Advisor, Brain Maturation: Function of Rapid Eye-Movement Sleep
Advised: Dale Hogan
1997 - 1999
Supervised Research, Ontogeny of Avian Sleep Neurophysiology
Advised: Grace Buchanan
1987 - 1988

Fellows supervised

NIH/NINDS grant, Research Advisor, 1 fellows supervised, NIH/NINDS grant Post-Doctoral fellow09/1997 - 08/1999

Residency Training

Psychiatry Resident Research Council Project, Research Advisor2007 - 05/2009