Daniela Rueedi-Bettschen, PhD
Assistant Professor
Department:
SOM-Psychiatry
Email:
drueedibettschen@umc.edu
Work Phone:
(601) 984-5890
Education
| Neuroscience Center Zurich, Switzerland, PhD, International Ph.D. Program in Neuroscience | 2004 |
| Laboratory of Behavioral Neurobiology, ETH Zurich, Zuric, PhD, Ph.D Behavioral Neuroscience | 2004 |
| ETH Zurich (Eidgenössische Technische Hochschule Zürich), Zurich, Switzerland, MS, Biology of Behavior Studies | 2000 |
| University of Bern, Bern, Switzerland, Veterinary Medicine Studies | 1995 |
Current Positions
| Director Animal Behavior Core, School of Medicine | 11/2021 - Present |
| Assistant Professor, School of Medicine, Department of Psychiatry | 07/2021 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Academic Appointments or Other Previous Appointments
| Associate Director CPN Animal Behavior Core, University of Mississippi Medical Center, School of Medicine, Department of Psychiatry | 08/2016 - 10/2021 |
| Instructor, University of Mississippi Medical Center, School of Medicine, Department of Psychiatry | 10/2013 - 06/2021 |
| Instructor, University of Arkansas for Medical Sciences, School of Medicine, Department of Pharmacology / Toxicology | 05/2008 - 08/2013 |
| Postdoctroal Research Fellow, Harvard Medical School, New England Primate Research, School of Medicine | 01/2006 - 04/2008 |
| Postdoctoral Research Fellow, ETH Zurich (Eidgenössische Technische Hochschule Zürich) | 2005 - 09/2005 |
Sponsored Program Funding
| Extramural, Consequences of fentanyl self-administration during pregnancy, NIH/NIDA | 04/2021 - 03/2023 |
| Extramural, GABA-A receptor subtype mechanisms and the abuse-related effects of alcohol, NIH/NIAAA | 09/2020 - 07/2025 |
| Intramural, Methamphetamine use during pregnancy, NIH/NIGMS | 06/2020 - 05/2022 |
| Intramural, Consequences of methamphetamine use during pregnancy, NIH/NIGMS | 06/2018 - 05/2019 |
| Intramural, Long-term consequences of in utero methamphetamine exposure, NIH/NIGMS | 09/2014 - 07/2017 |
| Extramural, Opioid Receptor Polymorphisms and Nonhuman Primate Models of Alcohol Abuse, NIH / NIAAA | 01/2009 - 01/2014 |
| Extramural, Active Immunization for Treating Methamphetamine Abuse, NIH / NIDA | 01/2007 - 01/2013 |
| Extramural, GABA-A receptor subtype mechanisms and the abuse-related effects of alcohol., NIH/NIAAA | 09/2006 - 07/2025 |
| Extramural, GABAA-Receptor Subtype Mechanisms in Nonhuman Primate Models of Alcohol Abuse, NIH / NIAAA | 01/2006 - 01/2017 |
| Extramural, Immunotherapy for Drug Abuse., NIH / NIDA | 01/1992 - 01/2009 |
Publications
Journal Article | |
| Golani L, Platt D, Rüedi-Bettschen D, Edwanker C, Huang S, Poe M, Furtmuller R, Sieghart W, Cook JM, Rowlett JK 8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABA A Receptor Front Pharmacol. 2021; 12:625233 | 2021 |
| Pryce CR, Rüedi-Bettschen D, Dettling AC, Weston A, Russig H, Ferger B, Feldon J Long-term effects of early-life environmental manipulations in rodents and primates: Potential animal models in depression research. Neurosci Biobehav Rev. 2005;29(4-5):649-74 | 2005 |
Abstracts | |
| Sasser J, Platt DM, Rüedi-Bettschen D Extended access to methamphetamine self-administration leads to altered maternal physiology and impaired offspring development College on Problems of Drug Dependence 82nd Annual Meeting, Hollywood, FL. | 2020 |
| Platt DM, Rüedi-Bettschen D, Cook LE, Li G, Poe M, Methuku K and Cook JM Contribution of alpha 2/3 GABA-A receptors to the abuse-related effects of ethanol in rhesus monkeys. Alcoholism: Clinical and Experimental Research. 2017; 41(S1):1A-363A | 2017 |
| Rüedi-Bettschen D, Rallapalli S, Clayton T, Cook J, Platt D Reinforcing effects of ethanol are attenuated by α5GABAA receptor inverse agonists in monkeys Alcoholism: Clinical and Experimental Research. 2015; 39(S1): 12A–249A | 2015 |
| Platt DM, Rüedi-Bettschen D, Rallapalli S, Cook JM Role of alpha-5/GABA(A) receptor mechanisms in the reinforcing effects of ethanol in monkeys. Behav Pharmacol 18, S29-30 | 2007 |
| Rüedi-Bettschen D, Zhang W, Weston A, Feldon J, Pryce CR Postnatal Manipulation leads to increased behavioural and cardiophysiological reactivity to aversive challenge in adult Fischer rats Acta Neurobiologiae Experimentalis. 2003; 63(5): E34 | 2003 |
Book Chapter | |
| Chandler CM, Overton JS, Rüedi-Bettschen D, Platt DM GABAA Receptor Subtype Mechanisms and the Abuse-Related Effects of Ethanol: Genetic and Pharmacological Evidence Grant K., Lovinger D. (eds) The Neuropharmacology of Alcohol. Handbook of Experimental Pharmacology, vol 248. Springer, Cham, 2018 | 2017 |
| Pryce CR, Rüedi-Bettschen D, Dettling AC, Feldon J Early-life environmental manipulations in rodents and primates: potential animal models in depression research. Handbook on Stress, Immunology and Behaviour Vol. 2. (Steckler T, Reul H, Kalin NH, eds). Amsterdam: Elsevier science, pp. 23-50. | 2005 |
Presentations
| State/Local Invited Seminars/Lectures, Drug use during pregnancy: lessons from a translationally- relevant rat model, Psychiatry Grand Rounds, UMMC | 02/2022 |
| Platform Presentations, Sex differences in offspring of maternal methamphetamine use, American Physiological Society; New Trends in Sex and Gender Medicine, Virtual Meeting | 10/2021 |
| Poster Presentation, Fentanyl abuse during pregnancy: deleterious effects on offspring development, MS IdeA, Jackson, MS | 07/2018 |
| Poster Presentation, Combination with pregnanolone increases the sedative effects of triazolam and zolpidem in rhesus macaques, CPDD, San Diego, CA | 06/2018 |
| Platform Presentations, In utero exposure to moderate doses of methamphetamine alters sensitivity to the same drug in adults, College on Problems of Drug Dependence, Montreal, Canada | 07/2017 |
| Poster Presentation, Methamphetamine self-administration during pregnancy in the rat: effects on dams and offspring., NIH, NIGMS Biennial IdeA Symposium of Biomedical Research Excellence, Washington, DC | 07/2016 |
| Poster Presentation, Consequences of self-administered methamphetamine throughout pregnancy on rat dams and their offspring., SE Regional IDeA Meeting, Biloxi, MS | 11/2015 |
| Poster Presentation, Consequences of self-administered methamphetamine throughout pregnancy on rat dams and their offspring., Society for Neuroscience, Chicago, IL | 10/2015 |
| Poster Presentation, Reinstatement of drug-seeking behavior in rats trained to self-administer intravenous injections of midazolam, The College on Problems of Drug Dependence, Phoenix, AZ | 06/2015 |
| Poster Presentation, Safety and efficacy of a novel anti-(+)-methamphetamine (METH) vaccine, The Collegeon Problems of Drug Dependence, Palm Springs, CA | 06/2012 |
| Poster Presentation, Efficacy and safety of chronic anti(+)-methamphetamine mAb7F9 treatment of (+)-methamphetamine (METH) induced locomotor activity in rats., AAPS National Biotechnology Conference, San Diego, CA | 05/2012 |
| Poster Presentation, Effects of early life stress on behaviour and hippocampal volume in adult Wistar and Lewis rats, Federation of European Neuroscience Societies, Amsterdam, Netherlands | 07/2010 |
| Poster Presentation, Alpha-5/GABAA receptor mechanisms and the reinforcing effects of ethanol in monkeys, College on Problems of Drug Dependence, San Juan, Puerto Rico | 06/2008 |
| National and International Invited Seminars/Lectures, The use of non-human primates in addiction research: Impact of receptor mechanisms on substance abuse and relapse, Universitäre Psychiatrische Kliniken, Basel, Switzerland | 04/2008 |
| Poster Presentation, Involvement of 5-HT2C receptor mechanisms in the serotonergic modulation of cocaine priming-induced reinstatement in squirrel monkeys, Society for Neuroscience, San Diego, CA | 10/2007 |
| Poster Presentation, Serotonergic modulation of cocaine priming-induced reinstatement: focus on 5-HT2C receptor mechanisms, College on Problems of Drug Dependence, Quebec City, Canada | 06/2007 |
| Poster Presentation, Early deprivation leads to reduced motivation for reward that can be restored with fluoxetine in adult Wistar rats, Society for Neuroscience, San Diego, CA | 10/2006 |
| Poster Presentation, Mu opioid receptor polymorphisms and naltrexone response in rhesus monkeys trained to self-administer alcohol, Society for Neuroscience, Atlanta, GA | 10/2006 |
| Poster Presentation, Effects of early maternal deprivation on anxiety- and depression-like behaviour and regional density of insulin receptors in adult Wistar rats, Federation of European Neuroscience Societies, Lisbon, Portugal | 07/2004 |
| Poster Presentation, Postnatal Manipulation leads to increased behavioural and cardiophysiological reactivity to aversive challenge in adult Fischer rats, Society for Neuroscience, New Orleans, LA | 11/2003 |
| Platform Presentations, Early Deprivation leads to reduced motivation and increased behavioural despair in the adult rat, International Behavioral Neuroscience Society | 06/2002 |
Honors, Awards, and Recognition
| Excellence in Research – Silver Medal Award, University of Mississippi Medical Center | 2021 |
| Young Investigator Travel Award, NIH, NIGMS Biennial National IdeA Symposium of Biomedical Research Excellence | 2016 |
| Travel Award, The College on Problems of Drug Dependence | 2007 |
| Smotherman-Hennessey-Wiley Award, Best student paper published in Developmental Psychobiology | 2005 |
| Travel Award, Swiss Society for Neuroscience | 2003 |
| Travel Award, International Behavioral Neuroscience Society | 2002 |
Professional Membership and Service
| The College on Problems of Drug Dependence, Member | 2019 - Present |
| American Association of Pharmaceutical Scientists, Member | 2012 |
| International Study Group Investigating Drugs as Reinforcers, Member | 2010 - Present |
| Society for Neuroscience, Member | 2008 - Present |
| Swiss Society for Neuroscience, Member | 2003 - 2005 |
Committee Service
| MEDICAL CENTER-ANIMAL CARE AND USE, Member | 2022 - Present |
| Institutional Animal Care and Use Committee, Member | 2012 - 2013 |
| Department of Animal Laboratory Medicine Advisory Committee, Member | 2009 - 2013 |
| Needle stick Committee, Member | 2007 - 2008 |
Teaching Experience
| NSCI701, Graduate, Course, Lecturer, Foundations of Neuroscience | Spring 2022 |
| NSCI 701, Graduate, Course, Lecturer, Foundations of Neuroscience | Spring 2021 |
| NSCI 708, Graduate, Course, Lecturer, Special Topics in Neuroscience | Summer 2020 |
| NSCI 701, Graduate, Course, Lecturer, Foundations of Neuroscience | Spring 2020 |
| 701, Graduate, Course, Lecturer, Foundations of Neuroscience | Spring 2019 |
| NSCI 701, Graduate, Course, Lecturer, Foundations of Neuroscience | Spring 2018 |
| NSCI 701, Graduate, Course, Lecturer, Foundations in Neuroscience | Spring 2017 |
| NSCI 701, Graduate, Course, Lecturer, Foundations in Neuroscience | Spring 2016 |
| NSCI 701, Graduate, Course, Lecturer, Foundations in Neuroscience | Spring 2015 |
Directed Student Learning
| Supervised Research, Advised: David Majure | 2019 - 2019 |
| Supervised Research, Advised: Ray Antonyraj | 2018 - 2018 |
| Supervised Research, Advised: Mitchell Read | 2017 - 2017 |
| Supervised Research, Advised: Brett Westbrook | 2009 - 2009 |
| Supervised Research, Advised: Eileen Kessler | 2007 - 2007 |
| Supervised Research, Advised: Anna Weston | 2003 - 2003 |