Drazen Raucher, PhD
Professor
Department:
SOM-Cell and Molecular Biology
Email:
draucher@umc.edu
Work Phone:
(601) 984-1510
Education
| Institute of Molecular Biophysics, Florida State University, PhD, molecular biophysics | 1995 |
| Josip J. Strossmayer's University, Osijek, Croatia, BS, mathematics and physics | 1988 |
Current Positions
| Professor, School of , Department of Biochemistry | 02/2012 - Present |
| Professor, School of Medicine, Department of Biochemistry | 2010 - Present |
| President and CEO | 07/2008 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Academic Appointments or Other Previous Appointments
| Associate Professor, University of Mississippi Medical Center, School of Graduate, Department of Biochemistry | 2007 - 2010 |
| Assistant Professor, University of Mississippi Medical Center, School of Graduate, Department of Biochemistry | 2002 - 2007 |
| Assistant Research Professor, Duke University, Durham, NC, School of , Department of Biomedical Engineering | 2000 - 2001 |
| Assistant Research Professor, Duke University, Durham, NC, School of , Department of Cell Biology | 1999 - 2000 |
| Post Doctoral fellow, Duke University, Durham, NC, School of , Department of Cell Biology | 1995 - 1999 |
| Teaching and Research Assistant, florida State University, Tallahassee, FL, School of , Department of Institute of Molecular Biophysics | 1991 - 1995 |
| Project Coordinator for Mathematical Models, IQuatro, Osijek, Croatia, School of | 1988 - 1991 |
| Teaching and Research Assistant, Josip J. Strossmayer's Univeristy, Osijek, Croatia, School of , Department of Physics and Mathematics | 1987 - 1988 |
| Project Coordinator for Mathematical Models | 1987 - 1988 |
Sponsored Program Funding
| Extramural, Toward Changing Glioblastoma Outcomes: Targeted drug delivery of an inhibitory biopolymer in conjunction with systemic chemotherapy, NCI | 07/2019 - 06/2022 |
| Extramural, Roles of inflammation and microRNA network in brain metastasis of breast cancer, NIH | 03/2018 - 02/2019 |
| Extramural, INTERN: Thermally Targeted Biopolymers for the Delivery of Anticancer Drugs, NSF | 01/2018 - 03/2018 |
| Extramural, REU :Thermally Targeted Biopolymers for the Delivery of Anticancer Drugs, NSF | 01/2017 - 08/2017 |
| Extramural, Thermally Targeted Biopolymers for the Delivery of Anticancer Drugs, National Science Foundation | 09/2016 - 10/2018 |
| Extramural, Thermally Targeted Biopolymers for the Delivery of Anticancer Drugs, NSF | 09/2016 - 08/2018 |
| Extramural, Mississippi CaP HBCU Undergraduate Research Training Program, Department of Defense | 07/2014 - 06/2017 |
| Extramural, Roles of hyaluronic acid in cancer stem cell niche, NIH | 03/2014 - 02/2019 |
| Extramural, Design of a Multifunctional Polypeptide for Application in Cancer Diagnosis and Treatment, Mississippi INBRE, Institutional Development Award (IDeA) | 10/2013 - 09/2016 |
| Extramural, Thermo-responsive bioploymers for tumor targeted delivery, National Science Foundation, iCorp Program | 10/2012 - 03/2013 |
| Extramural, Targeted Delivery of S100B Inhibitory Peptide to SCA1 Mouse Cerebellum, NIH/NINDS | 07/2010 - 06/2012 |
| Extramural, Thermally Targeted Delivery of c-Myc Inhibitory Polypeptides to Malignant Gliomas, National Cancer Institute/NIH | 07/2010 - 06/2012 |
| Extramural, Thermally Targeted Cell Cycle Inhibitors for the Treatment of Pancreatic Cancer, National Cancer Institute/NIH | 03/2010 - 02/2012 |
| Extramural, MRI-R2: Acquisition of Aviv XL-FDS Fluorescence Detection System, National Science Foundation | 01/2010 - 12/2012 |
| Extramural, Targeted Delivery of Therapeutic Peptides by Genetically Engineered Biopolymers, National Science Foundation | 08/2009 - 07/2012 |
| Extramural, Thermally Targeted Delivery of Therapeutic Peptides, National Cancer Institute | 06/2009 - 05/2010 |
| Intramural, Thermally Targeted Cell Cycle Inhibitory Polypeptides for the Treatment of Pancreatic Cancer, UMMC Intramural Research Support Program | 05/2009 - 04/2010 |
| Extramural, Role of Obesity in Increased Melanoma Tumor Growth, Mississippi INBRE (P20RR016476), from the National Center for Research Resources, National Institutes of Health. to Dr. Elizabeth Brandon | 07/2008 - 06/2012 |
| Extramural, Thermally Targeted Delivery of a c-Myc Inhibitory Peptide In Vivo Using Elastin-like Polypeptide, Department of Defense (DoD) Breast Cancer Research Program (BCRP) Era of Hope | 07/2008 - 06/2011 |
| Extramural, Nuclear bodies and ribonucleoprotein biogenesis, National Institute for Health | 04/2008 - 01/2013 |
| Extramural, Thermally Targeted Delivery of Therapeutic Polypeptides, Mississippi Federal & State Technology Partnership Program's (MS-FAST) | 11/2007 - 05/2008 |
| Extramural, Targeted Delivery of Doxorubicin by Thermoresponsive Polypeptides, SBIR/NCI with Houston Pharmaceuticals, Inc | 09/2007 - 09/2008 |
| Extramural, Targeted Delivery of Doxorubicin to Solid Tumors in vivo using Elastin-like Polypeptide, The Milheim Foundation for Cancer Research | 09/2007 - 08/2008 |
| Extramural, Targeted Delivery of c-Myc Inhibitory Polypeptides, National Cancer Institute | 07/2006 - 06/2008 |
| Extramural, Targeted Delivery of c-Myc Inhibitory Polypeptides, Wendy Will Case Cancer Fund | 07/2005 - 06/2006 |
| Intramural, Targeted Delivery of Doxorubicin by Thermally Sensitive Polypeptides, University of Mississippi Medical Center | 09/2003 - 08/2004 |
| Intramural, Targeted Delivery of Antisense Oligonucleotides to Solid Tumors by Thermally Sensitive, Genetically Engineered Polypeptides, American Cancer Society Institutional Research Grant | 07/2002 - 06/2003 |
Publications
Patent | |
| Raucher D., Bidwell G.L. 3rd, and Felix Kratz Composition for Targeted Delivery of an Active Agent and Method for Use Thereof provisional patent. | 2011 |
PATENTS | |
| Raucher, D., Bidwell, G.L. 3rd, and Eddie Perkins Composition for Targeted Delivery of a Cargo Molecule Across the Blood Brain Barrier and Method for Use Thereof provisional patent filed September 2011. Serial No: 61/326,336. | 2011 |
| Vig, Parminder and Raucher, D Composition and methods for targeted delivery of a THerapeutic Polypeptide to the cerebellum of a subject for treatment of neurodegenerative diseases USPTO provisional patent filed January 2010. Serial No:61/044,398 | 2010 |
| Raucher, D., Bidwell, G.L. 3rd, and Felix Kratz Composition for Targeted Delivery of an Active Agent and Method for Use Thereof provisional patent filed October 2009 | 2009 |
| Raucher, D., Bidwell, G.L. 3rd, and Iqbal Massodi Inhibition of Cancer Metastasis by Cell Penetrating Peptides Fused to Elastin-like Biopolymers US full utility patent filed September 2009. Serial No:61/044,422 | 2009 |
| Raucher, D., Bidwell, G.L. 3rd, and Iqbal Massodi Targeted Delivery of Therapeutic Peptides by Thermally Responsive Polymers US full utility patent filed September 2009. Serial No:61/044,398. | 2009 |
| Raucher, D., Bidwell, G.L. 3rd, Fokt I., and Priebe W Thermally Targeted Delivery of Medicaments PCT/US2007/061240 filed 09/08/2007. | 2007 |
Journal Article | |
| Gene L. Bidwell, III, Eddie Perkins, and Raucher, D A thermally targeted c-Myc inhibitory polypeptide inhibits breast tumor growth Cancer Letters, accepted | 2011 |
| Hearst, S. M., Walker, L.R., Shao, Q., Lopez , M., Raucher, D. and Vig, P. J. G The design and delivery of a thermally responsive peptide to inhibit S100B-mediated neurogeneration Journal of Neuroscience, In press | 2011 |
| Moktan, S., Ryppa, C., Kratz, F., and Raucher, D A thermally responsive biopolymer conjugated to an acidsensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis Investigational New Drugs, Epub 2010 Oct 12. PMID: 20938714 | 2010 |
| Gene Bidwell, III, Angela Whittom, Daniel Lyons, Emily Thomas, Michael Hebert, and Raucher D A Thermally Targeted Peptide Inhibitor of Symmetrical Dimethylation Inhibits Cancer Cell Proliferation Peptides. 2010 May;31(5):834-41. Epub 2010 Feb 16. PMID:20167239. | 2010 |
| Bidwell, G. L. 3rd and Raucher, D Cell penetrating elastin-like polypeptides for therapeutic peptide delivery Adv. Drug Deliv. Rev., 62(15):1486-96. PMID: 20478348. | 2010 |
| Massodi, I , Moktan, S., Rawat, A., Bidwell, G. L. 3rd and Raucher D I Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to thermally responsive polypeptide carrier Int. J. Cancer. 2010 Jan 15;126(2):533-44. | 2010 |
| Bidwell, G. L. 3rd , and Raucher, D Therapeutic Peptides for Cancer Therapy: Part I – Peptide Inhibitors of Signal Transduction Cascades Expert Opin Drug Deliv. 2009 Oct;6 (10):1033-47 | 2009 |
| Raucher, D. Moktan, S. , Massodi, I. and Bidwell, G. L. 3rd Therapeutic Peptides for Cancer Therapy: Part II – Cell Cycle Inhibitory Peptide and Apoptosis Inducing Peptides Expert Opin Drug Deliv. 2009 Oct;6(10):1049-64 | 2009 |
| Massodi, I , Bidwell, G. L. 3rd, Davis, A.N., Credit K. , Flessner M. and Raucher D Inhibition of Ovarian Cancer Cell Metastasis by a Fusion Polypeptide Tat-ELP Clinical and Experimental Metastasis, 2009;26(3):251-60. | 2009 |
| Bidwell, G. L. 3rd, Davis, A.N., and Raucher, D Targeting a c-Myc Inhibitory Polypeptide to Specific Intracellular Compartments using Cell Penetrating Peptides J Control Release. 2009 Apr 2;135(1):2-10. Epub 2008 Nov 28 | 2008 |
| Massodi, I. and Raucher, D. A thermally responsive Tat-elastin-like polypeptide fusion protein induces membrane leakage, apoptosis, and cell death in human breast cancer cells J Drug Targeting, H15H (H9):H 611 – 622. Nov 2007. | 2007 |
| Bidwell, G. L. 3rd and Raucher, D. A thermally targeted Elastin-like polypeptide - doxorubicin conjugate overcomes drug resistance Inv New Drugs, 25(4):313-26, 2007 | 2007 |
| [6] Bidwell, G. L. 3rd, Fokt, I., Priebe, W., and Raucher, D Development of Elastin-like polypeptide for thermally-targeted delivery of doxorubicin Biochem. Pharmacol. 73(5):620-31, 2007 | 2007 |
| Bidwell, G. L., 3rd and Raucher, D Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc Biochem Pharmacol. 2006 Jan 12;71(3):248-56 | 2006 |
| Massodi, I., Bidwell, G. L., 3rd, and Raucher, D Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery J Control Release. 2005 Nov 28;108(2-3):396-408 | 2005 |
| Bidwell, G. L., 3rd and Raucher, D. Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy Mol. Cancer Ther., 4: 1076-1085 | 2005 |
| Dreher M. R., D. Raucher, N. Balu, M. O. Colvin, S. M. Ludeman, A. Chilkoti Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy J. Control Release 91(1-2):31-43 | 2003 |
| [11] Chilkoti A., M.R. Dreher, D.E. Meyer, D. Raucher Targeted drug delivery by thermally responsive polymers Adv. Drug. Deliv. Rev. 54(5) 613-630 | 2002 |
| Raucher D., and A. Chilkoti Enhanced uptake of thermally responsive polypeptide drug carrier by tumor cells in response to its hyperthermia mediated phase transition Cancer Res. 61:7163-7177 | 2001 |
| Raucher D., and M. P. Sheetz Local anesthetics cause decrease in membrane-cytoskeleton adhesion and PIP2 levels J. Cell Sci. 114:3759-3766 | 2001 |
| Raucher D., and M. P. Sheetz Important role of membrane tension in lamellipodial extension J. Cell. Biol. 148(1):127-136 | 2000 |
| Raucher D., Stauffer, T, Chen, W., Shen, K., Guo S.,York, J. D.,Sheetz, M. P., and Meyer, T. Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion Cell 100:221-228 | 2000 |
| Raucher D., and M. P. Sheetz Characteristics of a membrane reservoir studied by membrane tethers extracted by a laser tweezers trap Biophys. J., 77(4):1992-2002 | 1999 |
| Raucher D., and M. P. Sheetz Membrane tension regulates endocytosis in mitosis J.Cell Biol. 144 (3): 497-506 | 1999 |
| Raucher D., Fajer E. A., Sar, C. P., Hideg, K., Zhao, Y., Kawai M. & P.G. Fajer Novel EPR spin label and its applications in actomyosin cycle Biophys J. 68 (4 Suppl):128S-133S | 1995 |
| Raucher D., Sar, C. P., Hideg, K. & P.G. Fajer Myosin catalytic domain flexibility in MgADP Biochemistry 33, 14317-14323 | 1994 |
| Raucher D. & P.G. Fajer Orientation and dynamics of myosin heads in aluminum fluoride induced pre-power stroke states Biochemistry 33, 11993-11999 | 1994 |
| Massodi, I , Thomas, E. and Raucher D I Application of Thermally Responsive Elastin-like Polypeptide Fused to a Lactoferrin-derived Peptide for Treatment of Pancreatic Cancer Molecules, 2009 Jun 4;14(6):1999-2015 | |
Review Article | |
| Raucher, D. Massodi, I. and Bidwell, G. L. 3rd. Thermally targeted delivery of chemotherapeutics and anti cancer peptides by Elastin-like Polypeptide. Expert Opin Drug Deliv. 5(3):353-369, Mar 2008. | 2008 |
Abstracts | |
| Teuta Opacak-Bernardi, Leslie Robinson, Khalid Abu Ajaj, Felix Kratz and Drazen Raucher In vitro evaluation of a thermally targeted conjugate of a highly potent doxorubicin derivative American Association for Cancer Research 102nd Annual Meeting: Proceedings; 2011 Apr 2-6; Orlando, FL | 2011 |
| Teuta Opacak-Bernardi, Lucio Miele, and Drazen Raucher Targeting Notch Signaling Pathway in Malignant Glioma by Inhibiting Mastermind-like (MAML) Transcriptional Function 4th Annual Mississippi Biophysical Consortium Meeting, June 2-3 2011, Oxford, MS | 2011 |
| Gene L. Bidwell, III, Eddie Perkins, and Drazen Raucher Thermally Targeted Delivery of a c-Myc Inhibitory Peptide to Breast Tumors in vivo using Elastin-like Polypeptide American Association for Cancer Research 102nd Annual Meeting: Proceedings; 2011 Apr 2-6; Orlando, FL | 2011 |
| Gene L. Bidwell, III, Eddie Perkins, and Drazen Raucher Thermally Targeted Delivery of a c-Myc Inhibitory Peptide to Breast Tumors in vivo using Elastin-like Polypeptide Department of Defense Era of Hope Meeting. 2011, Aug 2-5; Orlando, FL | 2011 |
| Gene L. Bidwell, III, Eddie Perkins, and Drazen Raucher Thermally Targeted Delivery of a c-Myc Inhibitory Peptide using Elastin-like Polypeptide Department of Defense Leading Innovative Networking and Knowledge Sharing (LINKS) Meeting. 2011, Feb 15-17; Washington, DC | 2011 |
| Leslie Robinson, Eddie Perkins, Lacey McNally, Drazen Raucher Tumor Accumulation and Biodistribution of a Thermally Responsive Cell Cycle Inhibitory Polypeptide In Vivo American Association for Cancer Research 102nd Annual Meeting: Proceedings; 2011 Apr 2-6; Orlando, FL | 2011 |
| Gene L. Bidwell, III, Eddie Perkins, and Drazen Raucher A cell penetrating peptide – fused c-Myc inhibitory polypeptide accumulates in brain tumors in rats and inhibits tumor growth American Association for Cancer Research 101st Annual Meeting: Proceedings; 2010 Apr 17-21; Washington, DC. | 2010 |
| Shama Moktan, Felix Kratz and Drazen Raucher Elastin-like polypeptide based thermally targeted delivery of methotrexate for ovarian cancer therapy American Association for Cancer Research 101st Annual Meeting: Proceedings; 2010 Apr 17-21; Washington, DC. | 2010 |
| Joshua Hughes, Lee Bidwell, Shadon Rollins, Eddie Perkins, Drazen Raucher Novel thermally targeted therapeutic peptide for the treatment of glioblastoma (GBM) American Association for Cancer Research and the Japanese Cancer Association conference Proceedings; 2010 Feb 5-9; Waikoloa, HI. | 2010 |
| Leslie Robinson, Felix Kratz and Drazen Raucher Thermally Targeted Delivery of Acid-labile Derivative of Doxorubicin by Elastin-like Polypeptide American Association for Cancer Research 101st Annual Meeting: Proceedings; 2010 Apr 17-21; Washington, DC. | 2010 |
| Emily Thomas, and Drazen Raucher Thermally targeted NF-kB inhibitory peptide peptide cancer therapy American Association for Cancer Research 101st Annual Meeting: Proceedings; 2010 Apr 17-21; Washington, DC | 2010 |
| Shama Moktan, and Drazen Raucher Thermally targeted proapoptotic peptide for cancer therapy American Association for Cancer Research 101st Annual Meeting: Proceedings; 2010 Apr 17-21; Washington, DC | 2010 |
| Shama Moktan, Claudia Ryppa, Felix Kratz, Drazen Raucher A novel Elastin-like polypeptide based thermally targeted delivery of paclitaxel for breast cancer therapy American Association for Cancer Research Annual Meeting: Proceedings; 2009 Apr 18-22; Denver, CO. Abstract nr 3680 | 2009 |
| Aruna Rawat and Drazen Raucher Application of thermally responsive NF-kB inhibitory peptide for the treatment of breast cancer American Association for Cancer Research Annual Meeting: Proceedings; 2009 Apr 18-22; Denver, CO. Abstract nr 3795. | 2009 |
| Sly, C., Massodi , I. and Raucher D. Thermally targeted delivery of Akt inhibitory peptide fused to thermally responsive Tat-ELP polypeptide Mississippi Academy of Sciences Vol 54,. 1:40 January 2009 | 2009 |
| Massodi, I. and Raucher, D. Inhibition of SKOV-3 ovarian cancer cell proliferation by a C-terminal p21 fragment attached to thermally responsive Bac-7-ELP1 American Association for Cancer Research Annual Meeting: Proceedings; 2008 Apr 14-18; San Diego, CA. Philadelphia (PA): AACR; 20078. Abstract nr 3875. | 2008 |
| Gene L. Bidwell, III, Aisha N. Davis, and Drazen Raucher Utilizing Cell Penetrating Peptides to Enhance the Potency of a Thermally Responsive c-Myc Inhibitory Polypeptide American Association for Cancer Research Annual Meeting: Proceedings; 2008 Apr 14-18; San Diego, CA. Philadelphia (PA): AACR; 2007. Abstract nr 5600. | 2008 |
| Massodi, I, and Raucher, D. A thermally responsive Tat-elastin-like polypeptide fusion protein induces membrane leakage, apoptosis, and cell death in human breast cancer cells In: American Association for Cancer Research Annual Meeting: Proceedings; 2007 Apr 14-18; Los Angeles, CA. Philadelphia (PA): AACR; 2007. Abstract nr 3885. | 2007 |
| Bidwell, G. L. 3rd, Davis, A.N., Fokt, I., Priebe, W., and Raucher, D. An elastin-like polypeptide - Doxorubicin fusion for thermally-targeted delivery and evasion of multidrug resistance. In: American Association for Cancer Research Annual Meeting: Proceedings; 2007 Apr 14-18; Los Angeles, CA. Philadelphia (PA): AACR; 2007. Abstract nr 2305 | 2007 |
| P. Kumar and Raucher D. Development of elastin-like polypeptides as a macromolecular carriers for a cytotoxic peptides Journal of the Mississippi Academy of Sciences, Jan 2006, Vol 51, No. 1. | 2006 |
| Bidwel, G.L. l III and Raucher D. Enhancing toxicity of topoisomerase II inhibitors using a c-Myc inhibiting polypeptide AACR Meeting Abstracts, Apr 2005; 2005: 1168 | 2005 |
| Massodi, G. L. Bidwell, III, and Raucher D. Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery Journal of the Mississippi Academy of Sciences, Vol 50, 1: 44, 2005 | 2005 |
| Bidwell G.L., III and Raucher D. Enhancing antiproliferative effect of topoisomerase II inhibitors using a c-Myc inhibiting polypeptide Journal of the Mississippi Academy of Sciences Vol 50,. 1:40 January 2005 | 2005 |
| Massodi, G. L. Bidwell, III, and Raucher D. Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery Proceedings of the American Society for Cell Biology 44th Annual Meeting International Conference, December 4-8, 2004, Vol 1. page 103. | 2004 |
| G.L. Bidwell III and Raucher D Application of thermally responsive polypeptides directed against c-Myc oncogene for cancer therapy AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Abstracts Nov 2003, 1003 | 2003 |
| Bidwell G.L., Skertich M. and Raucher D. Targeted delivery of thermally sensitive cytotoxic polypeptides Journal of the Mississippi Academy of Sciences, Vol 48, 1:22 , 2003. | 2003 |
| [13] Dreher, M. Raucher, D. Balu, N. Colvin, M. Hudeman, S. Chilkoti, A. Elastin-like polypeptide-doxorubicin conjugates for cancer therapy Engineering in Medicine and Biology, 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference. Vol 1: 524- 525 | 2002 |
| Moktan, Shama, Perkins, E., Kratz, F., and Raucher, D Anti-tumor activity of a thermally responsive polypeptide-doxorubicin conjugate in a syngeneic mouse breast cancer model American Association for Cancer Research 102nd Annual Meeting: Proceedings; 2011 April 2-6; Orlando, Florida | 2001 |
| Raucher D, and Chilkoti A. Enhanced uptake of thermally responsive polypeptide drug carrier by tumor cells in response to its hyperthermia mediated phase transition Proceedings of 28th Controlled Release Society Annual Meeting, Vol 1:23. 2001 | 2001 |
| Sheetz M. P., Felsenfeld D., Raucher D. and Galbraith C. Forces in and on membranes alter motility and adhesion Institute for Mathematics and Its Applications, Workshop proceedings - Cell Adhesion and Motility. Vol 1: p12 | 1999 |
| Raucher D., and M. P. Sheetz Local anesthetics cause decrease in membrane-cytoskeleton adhesion and PIP2 levels Mol. Biol. Cell Vol. 10: 42a | 1999 |
| Hochmuth R.M, Raucher, D., Ting-Beall, H. P.and M.P. Sheetz Membrane-cytoskeleton adhesion and detachment from cells with “excess” area Proceedings of the First Joint BMES/EMBS Conference, vol 1 ,47 | 1999 |
| Raucher D., and M. P. Sheetz Important role of membrane tension in lamellipodial extension Mol. Biol. Cell Vol. 9: 34a | 1998 |
| Raucher D., Stauffer T., Chen, W. York J., M. P. Sheetz and T. Meyer Membrane tension is regulated with phoshoinositol phospholipids Mol. Biol. Cell Vol. 9: 160a | 1998 |
| Raucher D., and M. P. Sheetz Characteristics of a membrane reservoir studied by membrane tethers extracted by a laser tweezers trap Biophys. J. 72. No 2:300a | 1997 |
| Raucher D., and M. P. Sheetz Membrane tension regulates endocytosis in mitosis Mol. Biol. Cell Vol. 9: 112a | 1997 |
| Raucher, D., E. A. Fajer, K. Hideg, C. P. Sár, Y. Zhao, M. Kawai, and P. G. Fajer A novel electron paramagnetic resonance spin label and its application to study the cross-bridge cycle Biophys. J. 68:128S-134S. [*, A4] | 1995 |
| Fajer P. G., Raucher D., Adhikari B. and L. Fajer Disorder-order transition of myosin heads and force generation Proceedings of Australian Society for Biophysics 1995 Annual Conference. Vol 1. p:65 | 1995 |
| Raucher D., Sar, C. P., Hideg, K. & P.G. Fajer Myosin catalytic domain flexibility in MgADP Biophys. J. 68: No 2. 161a | 1995 |
| Raucher D., Fajer E. A., Sar, C. P., Hideg, K., Zhao, Y., Kawai M. & P.G. Fajer Novel EPR spin label and its applications in actomyosin cycle Biophys J. 68 (4 Suppl):128S-133S | 1995 |
| Raucher D., Sar, C. P., Hideg, K. & P.G. Fajer Myosin catalytic domain flexibility in MgADP Biochemistry 33, 14317-14323 | 1994 |
| Raucher D. & P.G. Fajer Orientation and dynamics of myosin heads in aluminum fluoride induced pre-power stroke states Biochemistry 33, 11993-11999 | 1994 |
| Raucher D. and P. G. Fajer Pre-power stroke heads are disordered and immobile-an EPR study Biophys. J. Vol. 66. No 2. 234a | 1994 |
| Raucher D., Fajer E. A.,Sar, C. P., Hideg, K., Zhao, Y., Kawai M. & P.G. Fajer A non-perturbing label for myosin heads Biophys. J. 64:360a | 1993 |
| Gene L. Bidwell, III, Eddie Perkins, and Drazen Raucher Thermally Targeted Delivery of a c-Myc Inhibitory Peptide to Breast Tumors in vivo using Elastin-like Polypeptide Mississippi Biophysical Consortium Annual Meeting. June 2-3, Oxford, MS | |
| Gene L. Bidwell, III, Eddie Perkins, Joshua Hughes, Judy James, Majid Khan, and Drazen Raucher Treatment of Malignant Gliomas Using Thermally Targeted Peptide Therapeutics University of Mississippi Medical Center Radiology Research Day. June 16, Jackson, MS | |
Book Chapter | |
| Raucher D., and Moktan, S Thermo-responsive Polymers, Drug Delivery in Oncology, From Research Concepts to Cancer Therapy chapter to be published May 2010. | 2010 |
| Raucher D Application of Laser Tweezers to Studies of Membrane–Cytoskeleton Adhesion Chapter 17, Methods in Cell Biology, 2008, Pages 451-466 | 2008 |
Presentations
| National and International Invited Seminars/Lectures, Thermally Targeted Delivery of Therapeutic Peptides, Smart Polymer Systems 2010 conference organized by iSmithers, Atlanta, GA | 05/2010 |
| National and International Invited Seminars/Lectures, Thermally Targeted Delivery of Therapeutic Peptides and Chemotherapeutics, Rudjer Boskovic Institute, Zagreb, Croatia | 04/2010 |
| Poster Presentation, Thermally targeted delivery of Akt inhibitory peptide fused to thermally responsive Tat-ELP polypeptide., Mississippi Academy of Sciences, Olive Branch, Mississippi | 01/2009 |
| State/Local Invited Seminars/Lectures, How to get funding for translational research?, Biophysical Consortium, Oxford, MS | 05/2008 |
| State/Local Invited Seminars/Lectures, Thermally Targeted Delivery of Therapeutic Peptides and Chemotherapeutics, Mississippi Technology Alliance, Jackson, MS | 03/2008 |
| State/Local Invited Seminars/Lectures, Thermally Targeted Delivery of Therapeutic Peptides, University of Mississippi Medical Center, Department of Physiology, Jackson, MS | 01/2008 |
| National and International Invited Seminars/Lectures, Application of thermally sensitive genetically engineered elastin-like polypeptides in drug delivery, J. J. Strossmayer University, School of Midicint, J. J. Strossmayer University, Osijek, Croatia | 06/2006 |
| State/Local Invited Seminars/Lectures, Application of thermally sensitive genetically engineered elastin-like polypeptides in drug delivery, Jackson Cancer Research Group, University of Mississippi Medical Center | 06/2004 |
| National and International Invited Seminars/Lectures, Antiproliferative effect of thermally sensitive polypeptides directed against cellular oncogenes., Institute of Molecular Bioplysics, Florida State University, Tallahassee, Florida | 04/2004 |
| National and International Invited Seminars/Lectures, Targeted delivery of thermally sensitive cytotoxic polypeptides, Department of Biochemistry and Molecular Biology, Mississippi State University, Starkville, Mississippi | 03/2003 |
| National and International Invited Seminars/Lectures, Thermally sensitive polymers: physical properties and application in drug delivery, Department of Pharmacology, University of Mississippi Medical Center | 02/2003 |
| National and International Invited Seminars/Lectures, Thermally sensitive polymers: physical properties and application in drug delivery, Department of Physiology, University of Mississippi Medical Center | 10/2002 |
| National and International Invited Seminars/Lectures, Membrane tension is an important regulator of endocytosis: model, application and molecular mechanism., Department of Anatomy and Cell Biology, East Carolina University, Greenville, NC | 11/2001 |
| National and International Invited Seminars/Lectures, Membrane tension is an important regulator of endocytosis: model, application and molecular mechanism, Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia | 02/2001 |
| National and International Invited Seminars/Lectures, Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion, Department of Immunology, Georgia State University, Atlanta, Georgia | 02/2001 |
| National and International Invited Seminars/Lectures, Membrane tension is an important regulator of endocytosis: model, application and molecular mechanism, Department of Molecular Therapeutics, University of Texas, M.D. Anderson Cancer Center | 01/2001 |
| National and International Invited Seminars/Lectures, Membrane tension is an important regulator of endocytosis: model, application and molecular mechanism, Department of Biochemistry, University of Mississippi Medical Center | 01/2001 |
| National and International Invited Seminars/Lectures, Modulation of endocytosis rate during mitosis by membrane tension, AstraZeneca, PLC, Philadelphia, PA | 12/2000 |
| National and International Invited Seminars/Lectures, Membrane tension is an important regulator of endocytosis: model, application and molecular mechanism, Department of Bioengineering, University of California at San Diego | 11/2000 |
| National and International Invited Seminars/Lectures, Membrane tension is an important regulator of endocytosis: model, application and molecular mechanism., Department of Physics, Indiana University, BLoomington, IN | 11/2000 |
| National and International Invited Seminars/Lectures, Modulation of endocytosis rate during mitosis by membrane tension, Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada | 11/2000 |
| National and International Invited Seminars/Lectures, Membrane tension is an important regulator of endocytosis: model, application and molecular mechanism, Wellman Center for Photomedicine, Harvard Medical School, Boston, MA | 10/2000 |
| National and International Invited Seminars/Lectures, Modulation of endocytosis rate during mitosis by membrane tension, Eppley Institute for Research in Cancer, Nebraska Medical Center, Omaha, NE | 10/2000 |
| National and International Invited Seminars/Lectures, Membrane tension is an important regulator of endocytosis: model, application and molecular mechanism, Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI | 10/2000 |
| National and International Invited Seminars/Lectures, Membrane tension regulates cell spreading and lamellipodial extension rate., Department of Biology, University of Virginia, Charlottesville, Virginia | 10/2000 |
| National and International Invited Seminars/Lectures, Phosphatidylinositos 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion, Department of Bioengineering, University of Illinois at Chicato, Chicago, IL | 09/2000 |
| National and International Invited Seminars/Lectures, Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion., Netherlands Cancer Institute, Amsterdam, Netherlands | 09/2000 |
| National and International Invited Seminars/Lectures, Membrane tension regulates cell spreading and lamellipodial extension rate., Department of Pharmacology, University of Illinois at Chicato, Chicago IL | 08/2000 |
| Scientific Presentations, Pre-power stroke heads are disordered and immobile - an EPR study, 36th Biophysical Society Meeting, New Orleans, LA | 03/1994 |
Honors, Awards, and Recognition
| Excellence in Research Award, Gold Level | 2011 |
| Excellence in Research Award, Silver Level | 2010 |
| Excellence in Research Award, Bronze Level | 2006 |
| Michael Kasha Student Publication Award for an Outstanding Publication in Biophysics and Structural Biology, FLorida State University |
Professional Membership and Service
| National Health Institute, Reviewer, Ad Hoc Reviewer | 2010 |
| American Association for Cancer Research, Member | 2002 - Present |
| Mississippi Academy of Science, Member | 2002 - Present |
| Controlled Release Society, Member | 2001 - 2003 |
| American Society for Cell Biology, Member | 1996 - 2000 |
| Biophysical Society, Member | 1991 - 1996 |
| Acta Biomaterialia, Reviewer, Journal Article, Acta Biomaterialia | |
| Anti Cancer Drugs, Reviewer, Journal Article | |
| Anti-Cancer Drug Discovery, Editorial Advisory Board Member for Recent Patents | |
| Bankhead-Coley Cancer Research Program managed by the Florida Department of Health, Reviewer, Grant Proposal | |
| Biochemical Pharmacology, Reviewer, Journal Article | |
| Biomacromolecules, Reviewer, Journal Article | |
| Biomaterials, Reviewer, Journal Article | |
| Biophysical Journal, Reviewer, Journal Article | |
| Cancer Letters, Reviewer, Journal Article | |
| Current Pharmacological Design, Reviewer, Journal Article | |
| Experimental Pathology, Reviewer, Journal Article | |
| Expert Opinion in Drug Delivery, Reviewer, Journal Article | |
| International Journal of Molecular Scienc, Reviewer, Journal Article | |
| Italian Association for Cancer Research, Reviewer, Grant Proposal | |
| James and Esther King Biomedical Research Program, Reviewer, Grant Proposal | |
| Journal of Biomedical Materials Research, Reviewer, Journal Article | |
| Journal of Controlled Release, Reviewer, Journal Article | |
| Molecular Cancer Therapeutics, Reviewer, Journal Article | |
| National Institute for Health, Reviewer, Grant Proposal | |
| National Research Council-Romania, Reviewer, Grant Proposal | |
| National Science Foundation- Biomedical Engineering Program, Reviewer, Grant Proposal | |
| Neoplasia, Reviewer, Journal Article | |
| Oncogene, Reviewer, Journal Article | |
| Recent Patents on Drug Discovery, Reviewer, Journal Article | |
| Regular member- Merit Review Panel for Oncology Section A- Veterans Health Administration, Reviewer, Grant Proposal | |
| Regulatory Peptides, Reviewer, Journal Article | |
| U.S. Civilian Research and Development Foundation (CRDF), Reviewer, Grant Proposal |
Committee Service
| Imaging Core Facility Oversight Committee, Member | 2012 - Present |
| Graduate Program Review Committee, Member | 2009 - Present |
| UMMC Intramural Research Support Program Review Committee | 2008 - 2008 |
| Embryonic Stem Cell Oversight Committee | 2007 - Present |
| Mass Spectrometry Core Facility Oversight Committee, Member | 2007 - Present |
| UMMC ACS IRG Committee | 2007 - Present |
| Coordinating Team for Southern Association for Colleges and Schools accreditation, Member | 2005 - Present |
| School Of Graduate Studies - Curriculum Committee, Member | 2002 - Present |
Other Service
| Director of Graduate Program-Department of Biochemistry, Director | 2003 - Present |
Teaching Experience
| 740, Course Presenter, Advanced Biochemical Methods | |
| 604, Dentistry, Course, Course Presenter, Dental Biochemistry | Fall |
| 720, Department of Biochemistry Journal Club | Fall 2012 |
| 743, Graduate, Lecture, Course Presenter, Cellular Biochemistry II | Spring 2009 |
| 743, Graduate, Lecture, Course Presenter, Cellular Biochemistry I | Winter 2008 |
| 720, Department of Biochemistry Journal Club | Winter 2007 |
| 720, Department of Biochemistry Journal Club | Winter 2003 |
Directed Student Learning
| Internship Advisor, Advised: Ana-Matea Mikecin | 2010 - Present |
| Internship Advisor, Advised: Ashley Wells | 2009 - 2009 |
| Internship Advisor, Advised: Catherine Thomas | 2009 - 2009 |
| Dissertation Committee Chair, Thermally Targeted Delivery of NfKB Inhibitors Advised: Aruna Rawat | 2008 - Present |
| Internship Advisor, Advised: Joshua Hughes | 2008 - Present |
| Internship Advisor, Advised: Teuta Opacak-Bernardi | 2008 - Present |
| Supervised Research, Advised: Leslie Robinson | 2008 - Present |
| Internship Advisor, Advised: Channing Sly | 2008 - 2009 |
| Supervised Research, Advised: Andrew Gilder | 2007 - Present |
| Internship Advisor, Advised: Moonsung Choi | 2007 - Present |
| Internship Advisor, Advised: Sooim Shin | 2007 - Present |
| Internship Advisor, Advised: Preety Kumar | 2006 - 2007 |
| Advised: Aisha Davis | 2004 - 2004 |
| Internship Advisor, Advised: Adrienne Rembert | 2004 - 2004 |
| Internship Advisor, Advised: Brooke Myers | 2004 - 2004 |
| Internship Advisor, Advised: Preety Kumar | 2004 - 2004 |
| Supervised Research, Application of elastin-like polypeptide for delivery of cancer therapeutics and prevention of metastasis Advised: Iqbal Massodi | 2003 - 2007 |
| Dissertation Committee Chair, Application of Elastin-Like Polypeptide for Delivery of Cancer Therapeutics and Prevention of Metastasis Advised: Iqbal Massodi | 2003 - 2008 |
| Supervised Research, Advised: Chinwendu Onwubiko | 2003 - 2003 |
| Supervised Research, Advised: Kristin Weaver | 2003 - 2003 |
| Supervised Research, Biophysical studies of human telomeric DNA Advised: Jing Li | 2002 - 2006 |
| Dissertation Committee Chair, Development of Elastin-like Polypeptides for Thermally Targeted Delivery of Inhibitory Peptides and Small Molecule Drugs Advised: Gene Bidwell | 2002 - 2007 |
| Supervised Research, Development of Elastin-like polypeptides for thermally targeted delivery of inhibitory peptides and small molecule drugs Advised: Gene. L Bidwell III | 2002 - 2007 |
| Supervised Research, H1-mediated changed in the global chromatin dynamics of differentiating murine erythroleukemia cells Advised: Dhananjay Yellajoshyula | 2002 - 2006 |
| Supervised Research, Thermal denaturation studies of sequence and structural-selective nucleic acid binding ligands Advised: Xiaochun Shi | 2002 - 2006 |
| Internship Advisor, Advised: De Suomo | 2002 - 2004 |
| Supervised Research, Quantitative studies f proteins that interact with tubulin by analytical ultracentrifugation Advised: Christopher Sontang | 2002 - 2003 |
| Internship Advisor, Advised: Daniel Lyons | |
| Internship Advisor, Advised: Emily Thomas | |
| Internship Advisor, Advised: Myriam Doger | |
| Internship Advisor, Advised: Aisha Davis |