Peter N. Mittwede, MD, PhD

Peter N. Mittwede, MD, PhD

Assistant Professor

Department:
SOM-Orthopedic Surgery

Email:
pmittwede@umc.edu

Work Phone:
(601) 984-6525

Biography

Dr. Mittwede was born in South Carolina, but spent much of his childhood in Ankara, Turkey. He returned to the United States to attend Belhaven University. He then completed the MD/PhD program at the University of Mississippi Medical Center, with a PhD under the mentorship of Dr. Robert Hester in the Department of Physiology. His research collaborations led him to an interest in orthopaedic surgery. He then left Mississippi to complete an orthopaedic surgery residency program at UPMC in Pittsburgh, followed by a fellowship in orthopaedic trauma at Shock Trauma in Baltimore. In addition to his clinical practice, Dr. Mittwede is interested in education, community service, and orthopaedic trauma research, and hopes to foster continued growth within the department in these areas. Outside of medicine, Dr. Mittwede enjoys spending time with his family (wife and three children) and friends, as well as watching and playing a variety of sports.

Education

R Adams Cowley Shock Trauma Center, University of Maryland, Fellowship, Orthopaedic Trauma2023
University of Pittsburgh, Orthopaedic Surgery Residency, Clinician Scientist Training Track2022
University of Mississippi Medical Center, MD/PhD, Medicine/Physiology2016
Belhaven University, BS, Sports Medicine2008

Current Positions

Assistant Professor, School of Medicine09/2023 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Publications

Meta-Analysis

Isla A, Landy D, Teasdall R, Mittwede P, Albano A, Tornetta P 3rd, Bhandari M, Aneja A, Postoperative mortality in the COVID-positive hip fracture patient, a systematic review and meta-analysis. European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023 May;33(4):927-9352023

Consensus Development Conference

Mittwede PN, Murawski CD, Ackermann J, Görtz S, Hintermann B, Kim HJ, Thordarson DB, Vannini F, Younger ASE, International Consensus Group on Cartilage Repair of the Ankle, Revision and Salvage Management: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot & ankle international, 2018 Jul;39(1_suppl):54S-60S2018

Letter

Mittwede P, Wellness: A Surgical Resident's Perspective. Academic medicine : journal of the Association of American Medical Colleges, 2017 Jul;92(7):9002017
Mittwede PN, Noch EK, Guo MH, A closer look at attrition in MD–PhD programs. Academic medicine : journal of the Association of American Medical Colleges, 2014 Jul;89(7):958-92014

Journal Article

Murawski CD, Mittwede PN, Wawrose RA, Belayneh R, Tarkin IS, Management of High-Energy Tibial Pilon Fractures. The Journal of bone and joint surgery. American volume, 2023 Jul 19;105(14):1123-11372023
Charles SJ, Chen SR, Mittwede P, Rai A, Moloney G, Sabzevari S, Lin A, Risk factors for complications and reoperation following operative management of displaced midshaft clavicle fractures. Journal of shoulder and elbow surgery, 2022 Oct;31(10):e498-e5062022
Mittwede PN, CORR Insights®: Are 3D-printed Models of Tibial Plateau Fractures a Useful Addition to Understanding Fractures for Junior Surgeons? Clinical orthopaedics and related research, 2022 Jun 1;480(6):1178-11802022
Tarkin IS, Murawski CD, Mittwede PN, Temporizing Care of Acute Traumatic Foot and Ankle Injuries. The Orthopedic clinics of North America, 2022 Jan;53(1):95-1032022
Hogan MV, Ahn J, Egol KA, Mittwede PN, Research During Orthopaedic Training. The Journal of the American Academy of Orthopaedic Surgeons, 2022 Feb 15;30(4):e461-e4692022
Aneja A, Landy DC, Mittwede PN, Albano AY, Teasdall RJ, Isla A, Kavolus M, Inflammatory cytokines associated with outcomes in orthopedic trauma patients independent of New Injury Severity score: A pilot prospective cohort study. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2022 Jul;40(7):1555-15622022
Watters RJ, Verdelis K, Lucas PC, Jiang S, Chen Y, Lu F, Martin BM, Lukashova L, Pecar G, Morales-Restrepo A, Hankins M, Zhu L, Mittwede P, Hartmaier RJ, Alexander PG, Tseng GC, Weiss KR, Galson DL, Lee AV, Lee B, Oesterreich S, A Novel Mouse Model for SNP in Steroid Receptor Co-Activator-1 Reveals Role in Bone Density and Breast Cancer Metastasis. Endocrinology, 2021 Aug 1;162(8)2021
Mittwede PN, Gibbs CM, Ahn J, Bergin PF, Tarkin IS, Is Obesity Associated With an Increased Risk of Complications After Surgical Management of Acetabulum and Pelvis Fractures? A Systematic Review. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2021 Apr 19;5(4)2021
Yagi H, Kihara S, Mittwede PN, Maher PL, Rothenberg AC, Falcione ADCM, Chen A, Urish KL, Tuan RS, Alexander PG, Development of a large animal rabbit model for chronic periprosthetic joint infection. Bone & joint research, 2021 Mar;10(3):156-1652021
Mittwede PN, CORR Insights®: Surgical Skill Can be Objectively Measured From Fluoroscopic Images Using a Novel Image-based Decision Error Analysis (IDEA) Score. Clinical orthopaedics and related research, 2021 Jun 1;479(6):1395-13972021
Mittwede PN, CORR Insights®: Early Antibiotic Administration Is Associated with a Reduced Infection Risk When Combined with Primary Wound Closure in Patients. Clinical orthopaedics and related research, 2021 Mar 1;479(3):620-6222021
Mittwede PN, CORR Insights®: Residency Selection Preferences and Orthopaedic Career Perceptions: A Notable Mismatch. Clinical orthopaedics and related research, 2020 Jul;478(7):1526-15282020
Mittwede PN, Morales-Restrepo A, Fourman MS, Fu FH, Lee JY, Ahn J, Egol KA, Hogan MV, Research-Track Residency Programs in Orthopaedic Surgery: A Survey of Program Directors and Recent Graduates. The Journal of bone and joint surgery. American volume, 2019 Aug 7;101(15):1420-14272019
Xiang L, Thompson MS, Clemmer JS, Mittwede PN, Khan T, Hester RL, Early treatment with GLP-1 after severe trauma preserves renal function in obese Zucker rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2019 May 1;316(5):R621-R6272019
Narra SP, Mittwede PN, DeVincent Wolf S, Urish KL, Additive Manufacturing in Total Joint Arthroplasty. The Orthopedic clinics of North America, 2019 Jan;50(1):13-202019
Mittwede PN, Gottardi R, Alexander PG, Tarkin IS, Tuan RS, Clinical Applications of Bone Tissue Engineering in Orthopedic Trauma. Current pathobiology reports, 2018 Jun;6(2):99-1082018
Clemmer JS, Xiang L, Lu S, Mittwede PN, Hester RL, Hyperglycemia-Mediated Oxidative Stress Increases Pulmonary Vascular Permeability. Microcirculation (New York, N.Y. : 1994), 2016 Apr;23(3):221-92016
Mittwede PN, Clemmer JS, Bergin PF, Xiang L, OBESITY AND CRITICAL ILLNESS: INSIGHTS FROM ANIMAL MODELS. Shock (Augusta, Ga.), 2016 Apr;45(4):349-582016
Xiang L, Mittwede PN, Clemmer JS, Glucose Homeostasis and Cardiovascular Alterations in Diabetes. Comprehensive Physiology, 2015 Sep 20;5(4):1815-392015
Mittwede PN, Xiang L, Lu S, Clemmer JS, Hester RL, Oxidative stress contributes to orthopedic trauma-induced acute kidney injury in obese rats. American journal of physiology. Renal physiology, 2015 Jan 15;308(2):F157-632015
Clemmer JS, Xiang L, Lu S, Mittwede PN, Hester RL, β2-adrenergic regulation of stress hyperglycemia following hemorrhage in the obese Zucker rat. Physiological reports, 2014 Dec 1;2(12)2014
Lu S, Xiang L, Clemmer JS, Mittwede PN, Hester RL, Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels. Microcirculation (New York, N.Y. : 1994), 2014 Nov;21(8):754-602014
Xiang L, Lu S, Mittwede PN, Clemmer JS, Husband GW, Hester RL, β(2)-Adrenoreceptor blockade improves early posttrauma hyperglycemia and pulmonary injury in obese rats. American journal of physiology. Heart and circulatory physiology, 2014 Aug 15;307(4):H621-72014
Xiang L, Lu S, Mittwede PN, Clemmer JS, Hester RL, Inhibition of NADPH oxidase prevents acute lung injury in obese rats following severe trauma. American journal of physiology. Heart and circulatory physiology, 2014 Mar 1;306(5):H684-92014
Mittwede PN, Xiang L, Lu S, Clemmer JS, Hester RL, A novel experimental model of orthopedic trauma with acute kidney injury in obese Zucker rats. Physiological reports, 2013 Oct;1(5):e000972013
Xiang L, Clemmer JS, Lu S, Mittwede PN, Impaired blood pressure compensation following hemorrhage in conscious obese Zucker rats. Life sciences, 2013 Aug 14;93(5-6):214-2192013
Lu S, Xiang L, Clemmer JS, Gowdey AR, Mittwede PN, Hester RL, Impaired vascular KATP function attenuates exercise capacity in obese zucker rats. Microcirculation (New York, N.Y. : 1994), 2013 Oct;20(7):662-92013
Xiang L, Hester RL, Fuller WL, Sebai ME, Mittwede PN, Jones EK, Aneja A, Russell GV, Orthopedic trauma-induced pulmonary injury in the obese Zucker rat. Microcirculation (New York, N.Y. : 1994), 2010 Nov;17(8):650-92010

Editorial

Mittwede PN, Young Investigator Perspectives. A delicate balance: career development activities and laboratory research. American journal of physiology. Gastrointestinal and liver physiology, 2015 May 15;308(10):G805-62015

Honors, Awards, and Recognition

Outstanding Senior Resident Award, Department of Orthopaedic Surgery, University of Pittsburgh2022
Emerging Leader, American Orthopaedic Association2022
Distinguished Alumnus Award, Department of Sports Medicine, Belhaven University2016
Excellence in Medicine Leadership Award, AMA Foundation2015
Robert A. Mahaffey Memorial Award, School of Graduate Studies, University of Mississippi Medical Center2015
Caroline tum Suden/Frances Hellebrandt Professional Opportunity Award, American Physiological Society2015
Student of the Year Award, Associated Student Body, University of Mississippi Medical Center2014
Dean’s Service Award, School of Graduate Studies, University of Mississippi Medical Center2014
Young Investigator Award, Society for Experimental Biology and Medicine2014
Most Outstanding Student Award, Department of Sports Medicine, Belhaven University2008