Frances "Gail" G. Megason, MD

Frances "Gail" G. Megason, MD

Professor Emeritus

Department:
SOM-Pediatrics

Email:
gmegason@umc.edu

Work Phone:
(601) 984-5220

Education

Fred Hutchinson Cancer Research Center, Visiting Professor, Bone Marrow Transplant1994
University of Mississippi Medical Center, MD, Pediatric Hematology Oncology1993
University of Mississippi Medical Center, MD, Pediatrics1988
University of Mississippi Medical Center, MD, Medicine1985
University of Southern Mississippi, BS, Chemistry, ACS certified1981

Specialty Certification Licensure

Certification, Business Advantage, Certificate, Millsaps College12/2009 - Present
Certification, Pediatric Hematology Oncology, American Board of Pediatrics1994 - 12/2020
Certification, Pediatrics, American Board of Pediatrics1989 - 2021
Licensure, State Medical License, Mississippi State Board of Medical Licensure07/1989 - 06/2020

Current Positions

Medical Director, Batson Children's Hospital Lab, School of Medicine, Department of Pediatrics03/2012 - Present
Vice Chair, School of Medicine, Department of Pediatrics07/2006 - Present
Professor, School of Medicine, Department of Pediatrics06/2006 - Present
Director, Pediatric Hematology/Oncology, School of Medicine, Department of Pediatrics11/2005 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Clinical Medical Director, UMMC Cancer Institute, University of Mississippi Medical Center, School of Medicine, Department of Cancer Institute11/2011 - 06/2016
Director, Pediatric Hematology/Oncology Fellowship Program, University of Mississippi Medical Center, Department of Pediatrics07/2005 - 06/2010
Chief of Medical Staff, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics07/2008 - 06/2009
Associate Professor, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics06/2000 - 06/2006
Vice Chair, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics04/2002 - 04/2006
Director, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics04/1996 - 11/2005
Assistant Professor, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics1994 - 06/2000
Fellow, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics12/1991 - 12/1993
Instructor, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics06/1990 - 06/1991

Sponsored Program Funding

Extramural, Follow-up Through 180 Days of Treatment with Remestemcel-L, Mesoblast International05/2016 - 06/2060
Extramural, A Single-Arm, Prospective Study of Remestemcel-L, Ex-Vivo, Mesoblast International Sarl09/2015 - 06/2030
Extramural, A Multicenter, Open –Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Efficacy, and Immunogenicity of Daily Subcutaneous Administration of 5g/kg tbofilgrastim in Infants, Children, and Adolescents with Solid Tumors without Bone Marrow Involvement, PRA Health Sciences05/2015 - 06/2016
Extramural, 2013 Hyundai Hope Grant two-year research award from September 1, 2013-December 1, 2015 in the amount of 250,000. To be distributed in two equal installments. 1st installment, 125,000 on or before October 1, 2013 and 2nd installment 125,000 no later than December 1, 201409/2013 - 12/2015
Extramural, Portable TCD Sickle Cell Satellite Clinics, Mississippi Department of Health07/2008 - 07/2009
Extramural, COG Chair Grant Per case Reimbursement, CI Subaward, NIH, Children's Oncology Group05/2006 - 05/2030
Extramural, Childrens Oncology Group Phase I/Pilot, National Cancer Institute Subaward08/2002 - 01/2007
Extramural, National Childrens Cancer Fund per case and Speciment Reimbursement, NCI01/2001 - Present

Publications

Poster

Smith ML, Searcy J, Graves EP, Megason GC, Elkin D. Associations of Psychological and Demographic Factors Among Long Term Survivors of Pediatric Cancer2014
Hsu J, Gordon C, Herrington B, Majumdar S, Ahmad N, Navalkele P, Megason G Analysis of Provider Compliance with Long-Term Follow-up Children's Oncology Group Guidelines at a Rural University-Based Hospital: A Retrospective Chart Review. ASPHO Annual Conference 2011. Poster Presentation.2011
Forsythe A, Smith M, Megason G, Elkin D Cultural and Environmental Factors Associated with Morality of African American and Caucasian B-Precursor Acute Lymphocytic Leukemia Patients in Mississippi. ASPHO Annual Conference 2011. Poster Presentation2011
N Whipple, S Majumdar, C Gordon, A Hederman, MG Smith, A Forsythe, B Herrington, G Megason, R Iyer A Case Series of Deep Vein Thrombosis in Pediatric Sickle Cell Disease ASPHO (2010).

Poster presentation, ASPHO Meeting

Majumdar S, Smith MG, Megason GC, Iyer R, Kermode J. In vitro platelet activation in sickle cell disease under pathophysiological shear stress. (Poster presentation, ASPHO Annual Meeting) 2008.2008

Journal Article

Newman LA, Luter MA, Davis DB, Abdul-Rahman OA, Johnson JM, Megason GC. Congenital Amegakaryocytic Thrombocytopenia: A Case Series Indicating 2 Founder Variants in the Mississippi Band of Choctaw Indians. J Pediatr Hematol Oncol. 2017 Jul 102017
Ramani R, Megason G, Schallheim J, Karlson C, Vijayakumar V, Vijayakumar S, Hicks C. Integrative Analysis of MircroRNA-Medicated Gene Signatures and Pathways Modulating White Blood Cell Count in Childhood Acute Lymphoblastic Leukemia. Biomarker Insights. Mar 2017:12.2017
Vijayakumar V, Collier III AB, Chun R, Zhang X, Lowery R, Barr J, Hicks C, Megason G, Vijayakumar S. Multimodality Imaging in Pediatric Osteosarcoma in the Era of Image Gently and Image Wisely Campaign With a Close Look at the CT Scan Radiation Dose. J Pediatr Hematol Oncol. 2015 Nov 18.2015
Sitthi-Amorn J, Herrington B, Megason G, Pullen J, Gordon C, Hogan S, Koganti T, Hicks C. Transcriptome Analysis of Minimal Residual Disease in Subtypes of Pediatric B Cell Acute Lymphoblastic Leukemia. Clin Med Insights Oncol. 2015 May 24;9:51-60.2015
Hicks C, Vijayakumar V, Ramani R, Megason G, Schallheim J, Karlson C. Integrative Analysis of miRNA Mediated mRNA Signatures and Pathways Associated with White Blood Cell Count in Childhood ALL. Leukemia Research. 2015 May2015
Karlson CW, Haynes S, Faith MA, Elkin TD, Smith ML, Megason G Development of the family symptom inventory: a psychosocial screener for children with hematology/oncology conditions Pediatr Hematol Oncol. 2015 Mar;37(2):140-6.2015
Vijayakumar V, Lowery R, Zhang X, Rezeanu L, Barr J, Giles H, Vijayakumar S, Megason G. Pediatric Osteosarcoma: A Single Institution's Experience. South Med J. 2014 Nov;107(11):671-5. doi: 10.14423/SMJ.0000000000000187.2014
Majumdar S, Miller M, Khan M, Gordon C, Forsythe A, Smith MG, Megason G, Iyer R Outcome of overst troke in sickle cell anaemia, a single institution's experience. Br J Haematol. 2014 Jun;165(5):707-13. doi: 10.1111/bjh.12795. Epub 2014 Feb 26.2014
Chichar E, Makey KL, Gibson J, Chen F, Cole SA, Megason GC, Vijayakumar S, Miele L, and Gu JW Sunitinib significantly suppresses the proliferation, migration, and apoptosis resistance, tumor angiogenesis and growth of triple-negative breast cancers but increases breast cancer stem cells Vascular Cell 2014, 6:122014
Chindo Hicks1–3, Lucio Miele1, Tejaswi Koganti2, LaFarra Young-Gaylor4, Deidre Rogers2,
Vani Vijayakumar5 and Gail Megason3 Analysis of Patterns of Gene Expression Variation within
and between Ethnic Populations in Pediatric B-ALL
Publication Date: 27 Aug 2013

Type: Original Research

Journal: Cancer Informatics

Citation: Cancer Informatics 2013:12 155-173

doi: 10.4137/CIN.S11831
2013
Majumdar, S., Friedrich, C.A., Koch, C.A., Megason, G.C., Fratkin, J.D., Moll, G.W Compound Heterozygous Mutation With a Novel Splice Donor Region DNA Sequence Variant in the Succinate Dehydrogenase Subunit B Gene in Malignant Paraganglioma Pediatric Blood Cancer 2010, 54:4732010
Brown K, Subramony C, May W, Megason G, Liu H, Bishop P, Walker T, Nowicki M. Hepatic iron overload in children with sickle cell anemia on chronic transfusion therapy Journal of Pediatric Hematology Oncology. 2009; 31 (5): 309-3122009
Abdul-Rahman O, Gay H, Caldwell E, Megason GC Cryptococcal Sepsis Diagnosed by Bone Marrow Examination Journal of Pediatric Hematology/Oncology. 2004; 26 (8): 526-5282004
Caudill J, Giles H, Megason GC, Wyatt-Ashmead J, Nowicki M Recurrent Neuroblastoma with Gastric Invasion Journal of Pediatric Hematology/Oncology. 2004; 26 (8): 476-4792004
Applegate H, Webb P, Elkin TD, Neul S, Drabman R, Moll G, Pullen J, Smith MG, Iyer R, Megason GC Improving Parent Participation at Pediatric Diabetes and Sickle Cell Appointments Using a Brief Intervention Children's Health Care. 2003; 32 (2): 125-1362003
Megason GC Pediatric Bone Marrow Transplantation Pediatric Rounds. 1996; 8 (1): 4-51996
Hardy CL, Megason GC Specificity of Hematopoietic Stem Cell Homing Hematological Oncology. 1996; 14: 17-271996
Megason GC, Smith JC, Iyer RV Aplastic Crisis Due to Human Parvovirus (B19) as an Initial Presentation of Hereditary Spherocytosis Journal of the Mississippi State Medical Association. 1993; 34 (3): 107-1091994
Smith JC, Megason GC, Iyer RV, Andrew ME, Pullen DJ Clinical Characteristics of Children with Hereditary Hemolytic Anemias and Aplastic Crisis: A Seven Year Review Southern Medical Journal. 1994; 87 (7): 702-7081994
Megason GC Congenital Malignancies Mississippi Healthy Baby Update. 1992; 6(2): 21992
Elkin TD, Megason GC, Robinson A, Bock HG, Schrimsher G, Muenzer J Long-Term Neurocognitive Outcome in an Adolescent with Hurler-Scheie Syndrome Neuropsychiatric Disease and Treatment. 2006; 2 (3)
Bomgaars LR, Megason GC, Pullen J, Langevin AM, Kuhn J, Bernstein M, Blaney SM Phase I Trial of Irofulven (MGI-114) in Pediatric Patiens with Solid Tumors Pediatr Blood Cancer,vol. 47,no. 2,pp. 163-168, 2006
Hicks C, Sitthi-Amorn J, Douglas J, Ramani R, Miele L, Vijayakumar V, Karlson C, Chipeta J, Megason G. Molecular Analysis of Central Nervous System Disease Spectrum in Childhood Acute Lymphoblastic Leukemia. Clin Med Insights. 14 Mar 2016:10; 5-15.2016
Gratz KL, Kiel EJ, Latzman RD, Moore SA, Elkin TD, Megason GC, Tull MT Complex Interrelations of Trait Vulnerabilities in Mothers and their Infants. Infancy. 17 Jan 2015;20(3): 306-338.2015
Cuvelier GDE, Nemecek ER, Wahlstrom JT, Kitko CL, Lewis VA, Schechter T, Jacobsohn DA, Harris AC, Pulsipher MA, Bittencourt H, Choi SW, Caywood EH, Kasow KA, Bhatia M, Oshrine BR, Flower A, Chaudhury S, Coulter D, Chewning JH, Joyce M, Savaşan S, Pawlowska AB, Megason GC, Mitchell D, Cheerva AC, Lawitschka A, West LJ, Pan B, Al Hamarneh YN, Halevy A, Schultz KR, Benefits and challenges with diagnosing chronic and late acute GVHD in children using the NIH consensus criteria. Blood, 2019 Jul 18;134(3):304-3162019
Reddy A, Espinoza I, Cole D, Schallheim J, Poosarla T, Bhanat E, Zhou Y, Zabaleta J, Megason G, Gomez CR, Genetic Mutations in B-Acute Lymphoblastic Leukemia Among African American and European American Children. Clinical lymphoma, myeloma & leukemia, 2018 Dec;18(12):e501-e5082018
Whipple NS, Marion LL, Dansie DM, Murina AT, Megason GC, Vijayakumar V, Herrington BL, [(18)F]FDG-PET for evaluating pediatric Rosai-Dorfman disease. Pediatric hematology and oncology, 2018 Apr;35(3):177-1802018
Newman LA, Luter MA, Davis DB, Abdul-Rahman OA, Johnson JM, Megason GC, Congenital Amegakaryocytic Thrombocytopenia: A Case Series Indicating 2 Founder Variants in the Mississippi Band of Choctaw Indians. Journal of pediatric hematology/oncology, 2017 Oct;39(7):573-5752017
Vijayakumar V, Collier AB 3rd, Ruan C, Zhang X, Lowery R, Barr J, Hicks C, Megason G, Vijayakumar S, Multimodality Imaging in Pediatric Osteosarcoma in the Era of Image Gently and Image Wisely Campaign With a Close Look at the CT Scan Radiation Dose. Journal of pediatric hematology/oncology, 2016 Apr;38(3):227-312016
Karlson CW, Haynes S, Faith MA, Elkin TD, Smith ML, Megason G, Development of the family symptom inventory: a psychosocial screener for children with hematology/oncology conditions. Journal of pediatric hematology/oncology, 2015 Mar;37(2):140-62015
Bielack SS, Smeland S, Whelan JS, Marina N, Jovic G, Hook JM, Krailo MD, Gebhardt M, Pápai Z, Meyer J, Nadel H, Randall RL, Deffenbaugh C, Nagarajan R, Brennan B, Letson GD, Teot LA, Goorin A, Baumhoer D, Kager L, Werner M, Lau CC, Sundby Hall K, Gelderblom H, Meyers P, Gorlick R, Windhager R, Helmke K, Eriksson M, Hoogerbrugge PM, Schomberg P, Tunn PU, Kühne T, Jürgens H, van den Berg H, Böhling T, Picton S, Renard M, Reichardt P, Gerss J, Butterfass-Bahloul T, Morris C, Hogendoorn PC, Seddon B, Calaminus G, Michelagnoli M, Dhooge C, Sydes MR, Bernstein M, EURAMOS-1 investigators, Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015 Jul 10;33(20):2279-872015
Fraser C, Brown P, Megason G, Ahn HS, Cho B, Kirov I, Frankel L, Aplenc R, Bensen-Kennedy D, Munteanu M, Weaver J, Harker-Murray P, Open-label bendamustine monotherapy for pediatric patients with relapsed or refractory acute leukemia: efficacy and tolerability. Journal of pediatric hematology/oncology, 2014 May;36(4):e212-82014
Ku E, Thomas M, Ho CH, Whipple NS, Abdul-Rahman O, Megason GC, Herrington BL, Carmody JB, Charlton JR, Index of suspicion. Case 1: fever, diarrhea, jaundice, and confusion in an 18-year-old male. Case 2: severe anemia in a 6-month-old girl. Case 3: red urine in a 4-month-old boy. Pediatrics in review, 2014 Mar;35(3):129-352014
Majumdar S, Miller M, Khan M, Gordon C, Forsythe A, Smith MG, Megason G, Iyer R, Outcome of overt stroke in sickle cell anaemia, a single institution's experience. British journal of haematology, 2014 Jun;165(5):707-132014
Wagner JE Jr, Eapen M, Carter S, Wang Y, Schultz KR, Wall DA, Bunin N, Delaney C, Haut P, Margolis D, Peres E, Verneris MR, Walters M, Horowitz MM, Kurtzberg J, Blood and Marrow Transplant Clinical Trials Network, One-unit versus two-unit cord-blood transplantation for hematologic cancers. The New England journal of medicine, 2014 Oct 30;371(18):1685-942014
Vijayakumar V, Lowery R, Zhang X, Hicks C, Rezeanu L, Barr J, Giles H, Vijayakumar S, Megason G, Pediatric osteosarcoma: a single institution's experience. Southern medical journal, 2014 Nov;107(11):671-52014
Hsu JH, Gordon C, Megason G, Majumdar S, Ostrenga A, Herrington B, A rare case of peripheral neuropathy from relapse of acute lymphoblastic leukemia to the brachial plexus. Journal of pediatric hematology/oncology, 2012 Mar;34(2):e77-92012
Karlson CW, Leist-Haynes S, Smith M, Faith MA, Elkin TD, Megason G, Examination of risk and resiliency in a pediatric sickle cell disease population using the psychosocial assessment tool 2.0. Journal of pediatric psychology, 2012 Oct;37(9):1031-402012
Majumdar S, Friedrich CA, Koch CA, Megason GC, Fratkin JD, Moll GW, Compound heterozygous mutation with a novel splice donor region DNA sequence variant in the succinate dehydrogenase subunit B gene in malignant paraganglioma. Pediatric blood & cancer, 2010 Mar;54(3):473-52010
Baker DL, Schmidt ML, Cohn SL, Maris JM, London WB, Buxton A, Stram D, Castleberry RP, Shimada H, Sandler A, Shamberger RC, Look AT, Reynolds CP, Seeger RC, Matthay KK, Children’s Oncology Group, Outcome after reduced chemotherapy for intermediate-risk neuroblastoma. The New England journal of medicine, 2010 Sep 30;363(14):1313-232010
Brown K, Subramony C, May W, Megason G, Liu H, Bishop P, Walker T, Nowicki MJ, Hepatic iron overload in children with sickle cell anemia on chronic transfusion therapy. Journal of pediatric hematology/oncology, 2009 May;31(5):309-122009
Bomgaars LR, Megason GC, Pullen J, Langevin AM, Dale Weitman S, Hershon L, Kuhn JG, Bernstein M, Blaney SM, Phase I trial of irofulven (MGI 114) in pediatric patients with solid tumors. Pediatric blood & cancer, 2006 Aug;47(2):163-82006
Elkin TD, Megason G, Robinson A, Bock HG, Schrimsher G, Muenzer J, Longitudinal neurocognitive outcome in an adolescent with Hurler-Scheie syndrome. Neuropsychiatric disease and treatment, 2006 Sep;2(3):381-62006
Caudill J, Giles H, Megason G, Wyatt-Ashmead J, Gosche J, Nowicki M, Recurrent neuroblastoma with gastric invasion. Journal of pediatric hematology/oncology, 2004 Aug;26(8):476-92004
Abdul-Rahman OA, Gay H, Caldwell E, Megason GC, Cryptococcal sepsis diagnosed by bone marrow examination. Journal of pediatric hematology/oncology, 2004 Aug;26(8):526-82004
Forsythe A, Breland T, Majumdar S, Elkin TD, Johnson D, Megason G, Gender differences in incidence rates of childhood B-precursor acute lymphocytic leukemia in Mississippi. Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses, 2010 May-Jun;27(3):164-7
Hicks C, Miele L, Koganti T, Young-Gaylor L, Rogers D, Vijayakumar V, Megason G, Analysis of Patterns of Gene Expression Variation within and between Ethnic Populations in Pediatric B-ALL. Cancer informatics, 2013;12:155-73
Chinchar E, Makey KL, Gibson J, Chen F, Cole SA, Megason GC, Vijayakumar S, Miele L, Gu JW, Sunitinib significantly suppresses the proliferation, migration, apoptosis resistance, tumor angiogenesis and growth of triple-negative breast cancers but increases breast cancer stem cells. Vascular cell, 2014;6:12
Sitthi-Amorn J, Herrington B, Megason G, Pullen J, Gordon C, Hogan S, Koganti T, Hicks C, Transcriptome Analysis of Minimal Residual Disease in Subtypes of Pediatric B Cell Acute Lymphoblastic Leukemia. Clinical Medicine Insights. Oncology, 2015;9:51-60
Hicks C, Sitthi-Amorn J, Douglas J, Ramani R, Miele L, Vijayakumar V, Karlson C, Chipeta J, Megason G, Molecular Analysis of Central Nervous System Disease Spectrum in Childhood Acute Lymphoblastic Leukemia. Clinical Medicine Insights. Oncology, 2016;10:5-15

Review Article

Ku E, Whipple NS, Carmody JB, Thomas M, Ho CH, Abdul-Rahman O, Megason GC, Herrington BL, Charlton JR Index of Suspicion Pediatrics in Review;2014;35;129
American Academy of Pediatrics, Elk Grove Village, IL
2014

Abstracts

Karlson, C. W., Leist-Haynes, S., Smith, M., Faith, M. A., Elkin, T. D., & Megason, G. Longitudinal risk and resiliency in a pediatric sickle cell population Journal of Pediatric Psychology, 37, 1031-1040.2012
Gordon C, Megason GC, Ledbetter A Clofarabine-Induced Remission in Relapsed Pediatric Acute Myelogenous Leukemia Biology of Blood and Marrow Transplantation. 2009; 15 (2)2009
Majumdar S, Robertson Z, Robinson A, Starnes S, Iyer R, Megason GC Outcome of Hematopoietic Cell Transplantation in Children with Sickle Cell Disease, A Single Center's Experience Blood. 2007; 110 (11); 337a2007
Herrington BL, Iyer RI, Smith MG, Abdul-Rahman OA, Megason GC Pearson Syndrome Journal of Investigative Medicine. 2007; 55 (1)2007
Majumdar S, Robinson A, Files J, Megason, GC Second Allogeneic Bone Marrow Transplant in a Child With Sickle Cell Disease Using a Reduced-Intensity Conditioning Regimen as a "Boost" For Progressively Decreasing Donor Chimerism Journal of Investigative Medicine. 2007; 55 (1)2007
Megason GC, Venarske DL, Yates AB Bone Marrow Failure Associated with Hypogammaglobulinemia Journal of Investigative Medicine. 2001; 49 (1): 124A2001
Cox JA, Megason GC, Iyer RV, Smith MG, Mitchell TE, Pullen DJ Nasopharyngeal Carcinoma in a Patient with Dominant Dystrophic Epidermolysis Bullosa Journal of Investigative Medicine. 2001; 49 (1): 106A2001
Megason GC, Weitman S, Blaney S, Winick N, Kuhn J, Pullen J, Bernstein M A Trial of 6-Hydroxymethylacylfulvene (MGI-114) in Children With Solid Tumors, A Pediatric Oncology Group (POG) Phase 1 Cooperative Agreement Study Proceedings of American Society of Clinical Oncology. 2000; 19: 201a2000
Mitchell TE, Megason GC, Smith MG Recurrent Neuroblastoma Presenting as an Isolated Central Nervous System Lesion Following Intense Chemotherapy, Surgical Resection and Autologous Stem Cell Transplant Journal of Investigative Medicine. 1999; 47 (2): 115a1999
Mitchell TE, Megason GC, Vedanarayan VV, Yates AB Neurological complications post influenza vaccination in a child with Chediak-Higashi syndrome Journal of Pediatric Hematology/Oncology. 1998; 19 (4): 3821998
Prasad A, Megason GC Retrospective study of acute idiopathic thrombocytopenic purpura (ITP) in children at a tertiary care center Journal of Investigative Medicine. 1997; 45 (1): 10a1997
Megason GC, Sullivan KM, Nims S, Flowers MD, Bowden R, Appelbaum FR, Storb R Osteomyelitis and septic arthritis developing late after bone marrow transplantation Blood. 1995; 86 (10): 958a1995
Coleman M, Megason GC, Steinberg M Delta and Gamma Globin Gene Expression in Bursts of Heterozygous Thalassemia Blood. 1994; 84 (10): 263a1994
Megason GC, Moulder S, Pullen DJ The use of in vitro culture assays to predict in vivo response to various therapeutic modalities in a patient with Diamond Blackfan anemia Journal of Cellular Biochemistry. 1994; 18 (A): 331994
Hatten BH, Megason GC, Kruckeberg WC Concentrations of amino acids in cerebrospinal fluids: Establishing in house reference ranges Proceedings of the Greenwood Genetics Center. 1993; 12:1531993
Megason GC, Hardy CL, DeBauche DM, Lewis RE, Pullen DJ Synergistic effects of hematopoietic cytokines on in vitro cultures from patients with acute myelogenous leukemia Blood. 1993; 82 (10): 651a1993
Megason GC, Hatten BH, Kruckeberg WC, Pullen J The evaluation of secondary hyperphenylalaninemia by measuring the level of phenylalanine in the cerebrospinal fluid of children receiving methotrexate chemotherapy Proceedings of the Greenwood Genetic Center. 1993; 12:1551993
Moulder S, Megason GC, Pullen DJ The use of cell culture models to determine a possible course of treatment for a patient with Diamond Blackfan anemia Journal of Clinical Research. 1993; 40 (4): 730a1993
Megason GC, Smith JC, Iyer RV, Pullen DJ Aplastic crisis due to human parvovirus (B19) in two patients with glucose 6 phosphate dehydrogenase G6PD) deficiency Journal of Clinical Research. 1992; 40 (4): 785a1992
Majumdar, S., Robinson, A., Files, J., Megason, G.C. Division of Pediatric Hematology/Oncology, University of Mississippi Medical Center, Jackson, MS 39216. . “Second Allogeneic Bone Marrow Transplant in a Child With Sickle Cell Disease Using a Reduced-Intensity Conditioning Regimen as a “Boost” For Progressively Decreasing Donor Chimerism Journal of Investigative Medicine. 55 (1) Jan 2007.
Hsu JH, Gordon C, Megason G, Majumdar S, Ostrenga A, Herrington B. A Rare Case of Peripheral Neuropathy From Relapse of Acute Lymphoblastic Leukemia to the Brachial Plexus J Pediatr Hematol Oncol. 2011 Jul 15.
MG smith, C Gordon, A. Palmer, G Megason, R Iyer Chromobacterium Violacum Infection in a Patient with Sickle Cell Anemia (6th Annual Sickle Cell Disease Research and Education Symposium) 6th Annual Sickle Cell Disease Research and Education Symposium) Hollywood Florida; February 2012.
Forsythe,A., Breland,T., Majumdar,S., Elkin,D., Johnson,D., and Megason, G. Gender Differences in Incidence Rates of Childhood B-Precursor Acute Lymphocytic Leukemia in Mississippi Journal of Pediatric Oncology Nursing, May 2010; vol. 27: pp. 164 - 167.
Karlson, C. W., Leist-Haynes, S., Smith, M., Faith, M. A., Elkin, T. D., & Megason, G Longitudinal risk and resiliency in a pediatric sickle cell population. Journal of Pediatric Psychology. doi: 10.1093/jpepsy/jss087
C Fraser, P Brown, G. Megason, H. Ahn, B. Cho, I. Kirov, L. Frankel, R. Aplenc, D. Benson-Kennedy, M. Munteanu, J. Weaver, P. Harker-Murray. Open-Label Bendamustine for Pediatric Patients with Relapsed or Refractory Acute Leukemia: Safety and Efficacy Outcomes Poster Presentation at ASH 2011.
Majumdar S, Robertson Z, Robinson A, Starnes S, Iyer R, Megason GC Outcome of hematopoietic cell transplantation in children with sickle cell disease, a single center’s experience Blood. 2007; 110 (11): 337a (Poster presentation, ASH Annual Meeting, Dec 2007). Manuscript in submission.
Karlson, C. W., Smith, M. L., Leist-Haynes, S., Faith, M. A., Pierce, J., Elkin, T. D., &
Megason, G. Risk for psychosocial problems in pediatric cancer: Impact of socioeconomics. Journal of Child Health Care
Majumdar, S., Morris, A., Gordon,C., Kermode, J.C., Forsythe, A., Herrington, B., Megason,G.C. and Iyer, R., “Alarmingly high prevalence of obesity in haemophilia in the state of Mississippi” Haemaphilia. 2010 May;16(3): 455-459.
21. Herrington, B.L., Iyer, R.V., Smith, M.G., Abdul-Rahman, O.A., Megason, GC. Department of Pediatric Hematology/Oncology, University of Mississippi Medical, Jackson, MS 39216. “Pearson Syndrome.” Journal of Investigative Medicine. 55 (1) Jan 2007

Clinical Trial

Shenoy S, Eapen M, Panepinto JA, Logan BR, Wu J, Abraham A, Brochstein J, Chaudhury S, Godder K, Haight AE, Kasow KA, Leung K, Andreansky M, Bhatia M, Dalal J, Haines H, Jaroscak J, Lazarus HM, Levine JE, Krishnamurti L, Margolis D, Megason GC, Yu LC, Pulsipher MA, Gersten I, DiFronzo N, Horowitz MM, Walters MC, Kamani N, A trial of unrelated donor marrow transplantation for children with severe sickle cell disease. Blood, 2016 Nov 24;128(21):2561-25672016
Darwish M, Megason G, Bond M, Hellriegel E, Robertson P Jr, Grasela T, Phillips L, Population pharmacokinetics and pharmacokinetics/pharmacodynamics of bendamustine in pediatric patients with relapsed/refractory acute leukemia. Current medical research and opinion, 2014 Nov;30(11):2305-152014

Presentations

State/Local Invited Seminars/Lectures, Understanding VOD & Defitelio: The First and Only Approved Treatment of VOD, Jazz Pharmaceuticals, Jackson, MS07/2017
State/Local Invited Seminars/Lectures, Understanding VOD & Defitelio: The First and Only Approved Treatment for VOD with Renal or Pulmonary Dysfunction Post-HSCT, Jazz Pharmaceuticals, Jackson, MS06/2017
Sickle Cell Support Group, Mississippi Sickle Cell Foundation Gulf Coast Chapter Presents "A Sickle Cell Patient/Advocate Support Group", Mississippi Sickle Cell Foundation, Gulfport, MS06/2017
Poster Presentation, Race-specific Genetic Aberrations in B-Acute Lymphoblastic Leukemia in Children, ASCO, Chicago, IL06/2017
State/Local Invited Seminars/Lectures, "Erwinaze in the Treatment of ALL: A Case-Based Approach", Jazz Pharmaceuticals, Ridgeland, MS06/2016
State/Local Invited Seminars/Lectures, "Erwinase", Jazz Pharmaceuticals, Ridgeland, MS05/2015
State/Local Invited Seminars/Lectures, "The Ethics of Authorship", Physiology Conference, CW 30605/2015
Poster Presentation, HSCT Outcomes of Native American Patients with c-MPL Mutations., ASPHO, Phoenix, AZ05/2015
Poster Presentation, Improving Time To Antibiotic Delivery in Patients With Febrile Neutropenia Using An Electronic Standardized Order Set., PAS Annual Meeting, San Diego,CA04/2015
State/Local Invited Seminars/Lectures, "BMT", Mississippi College, Dr. Stephanie Carmicle, Ph.D., Mississippi College02/2015
Invited Discussion on Local Talk Show, "BMT", MS Public Broadcasting, Southern Remedy01/2015
Platform Presentations, "Erwinase", Jazz Pharmaceuticals, Ruth Chris' Steak House06/2014
State/Local Invited Seminars/Lectures, “Staying Connected, Facilitating the Learning Experience During and After Cancer Treatment”, Leukemia & Lymphoma Society, Hattiesburg, MS10/2012
State/Local Invited Seminars/Lectures, “Staying Connected, Facilitating the Learning Experience During and After Cancer Treatment”, Leukemia & Lymphoma Society, Pearl, MS03/2012
State/Local Invited Seminars/Lectures, “How to make Informed Choices about Standard Care and Clinical Trials”, Leukemia & Lymphoma, Jackson, MS11/2011
State/Local Invited Seminars/Lectures, “Childhood Cancers, Who, What, When, Why?”, Mississippi Partnership for Comprehensive Cancer Control Conference, Jackson, MS05/2011
State/Local Invited Seminars/Lectures, “Children with Special Health Care Needs”, Mississippi State Department of Health Conference, Jackson, MS04/2010
State/Local Invited Seminars/Lectures, “Heavy Metal Anemia’s and the Newborn Blues”, American Academy of Pediatrics, Jackson, MS04/2010
Poster Presentation, Clofarabine-Induced Remission in Relapsed Pediatric Acute Myelogenous Leukemia, BMT Tandem Meeting/ASBMT and CIBMTR, Tampa, FL02/2009
Poster Presentation, In vitro platelet activation in sickle cell disease under pathophysiological shear stress, American Society of Pediatric Hematology and Oncology, Cincinati, OH05/2008
Poster Presentation, Outcome of hematopoietic cell transplantation in children with sickle cell disease, a single center’s experience, American Society of Hematology, Atlanta, GA12/2007
National and International Invited Seminars/Lectures, Hematology and Oncology, Prep the Course Conference/American Academy of Pediatrics, Philadelphia, PA09/2007
National and International Invited Seminars/Lectures, Hematology and Oncology, Prep the Course Conference/ American Academy of Pediatrics, Costa Mesa, CA03/2007
State/Local Invited Seminars/Lectures, Pediatric Oncology, Louisana/Mississippi Societies for Clinical Laboratory Science, Jackson, MS04/2006
National and International Invited Seminars/Lectures, Hope Conference, Leuekmia and Lymphoma Society and American Cancer Society02/2005
Poster Presentation, Effect on Platelet and Neutrophil Recovery of Administration of Filgrastim Post Transplant in Autologous Transplant Recipients, American Society of Hematology, San Diego, CA12/2003
Poster Presentation, Treatment of Choctaw Indian Sisters with Concomitant Bone Marrow Failure and Hypogammabloulinemia with Matched Sibling Peripheral Blood Stem Cell Transplantation. Poster Presentation Marrow Transplantation in Children, The Nemours Foundation, Dupont Hospital for Children11/2001
State/Local Invited Seminars/Lectures, Survivor's Perception, American Cancer Society, Petal, MS Relay for Life05/2001
State/Local Invited Seminars/Lectures, New Treatment Approaches in Pediatric Oncology, Louisana/Mississippi Societies for Clinical Laboratory Science, Jackson, MS04/2000
Poster Presentation, A Trial of 6-Hydroxymethylacylfulvene (MGI-114) in Children With Solid Tumors, A Pediatric Oncology Group (POG) Phase 1 Cooperative Agreement Study, American Society of Clinical Oncology2000
State/Local Invited Seminars/Lectures, Research Update, American Cancer Society, Vicksburg, MS Relay for Life11/1999
Poster Presentation, Recurrent Neuroblastoma Presenting as an Isolated Central Nervous System Lesion Following Intense Chemotherapy, Surgical Resection and Autologous Stem Cell Transplant, Southern Society of Pediatric Research, Chicago, IL02/1999
National and International Invited Seminars/Lectures, Reducing Resident Stress, Pediatric Program Coordinators Seminar, San Francisco, CA08/1998
Poster Presentation, Neurological complications post influenza vaccination in a child with Chediak-Higashi syndrome, American Society of Pediatric Hematology and Oncology, ASPHO 1997 Annual Meeting09/1997
Poster Presentation, Delta and Gamma Globin mRNA in Erythroid Bursts in Heterozygous  Thalassemia, Hemoglobin Switching06/1994
Poster Presentation, The use of cell culture models to determine a possible course of treatment for a patient with Diamond Blackfan anemia, Southern Society of Pediatric Research, Seattle, WA02/1994
Poster Presentation, The use of in vitro culture assays to predict in vivo response to various therapeutic modalities in a patient with Diamond Blackfan anemia, Keystone Symposia on Hematopoesis, Breckenridge, CO1994
Poster Presentation, Coagulation abnormalities in patients with sickle cell disease and cerebrovascular accidents, National Sickle Cell Disease Program, Washington, D.C.05/1993
Poster Presentation, Aplastic crisis due to human parvovirus (B19) in two patients with glucose 6 phosphate dehydrogenase G6PD) deficiency, Southern Society of Pediatric Research, New Orleans, LA1993
Poster Presentation, Epidemiology of human parvovirus infection and aplastic crisis in patients with chronic hemolytic anemias in a tertiary care center, Southern Medical Association, San Antonio, TX11/1992
Poster Presentation, Concentrations of amino acids in cerebrospinal fluids: Establishing in house reference ranges, Southern Genetics Group, Greenwood, MS07/1992
Poster Presentation, The evaluation of secondary hyperphenylalaninemia by measuring the level of phenylalanine in the cerebrospinal fluid of children receiving methotrexate chemotherapy, Southern Genetics Group, Greenwood, MS07/1992

Honors, Awards, and Recognition

Best Doctors2020
Evans Award, High Performance and Patient Satisfaction, UMMC, Department of Pediatrics2016
Evans Award, Dept of Pediatrics UMC2016
University of Southern Mississippi Hall of Fame, University of Southern Mississippi2015
Best Doctor 20112011
Guide to America's Top Pediatricians2010
Guide to America's Top Pediatricians2006
Holliman Award for Outstanding Pediatric Faculty, Residents, Department of Pediatrics2000

Professional Membership and Service

Journal of Clinical Psychology in Medical Settings2008 - Present
Mississippi Department of Health Genetics Advisory Board, Member2007 - Present
AAP Prep the Course, Member2007
American Society of Hematology, Member, Government Affairs Committee2007 - 2015
Leukemia and Lymphoma Society, Member, Hope Conference2006
Children's Oncology Group, Principal Investigator2006 - 2016
Leukemia Lymphoma Society, Board of Advisors of a Company2002 - 2012
American Cancer Society, Medical Director, Camp Rainbow Committee2000 - Present
Children's Cancer Fund, Advisory Board2000 - Present
Southern Society of Pediatric Research, Member, Session on Hematology Oncology1999 - 2000
Mississippi Society of Parenteral and Enteral Nutrition, Officer, President/Elect/Past1998 - 1999
Pediatric Program Coordinators Seminar, Reducing Resident Stress1997 - 1998
Southern Society of Pediatric Research, Adolescent Medicine and Medical Education1997 - 1998
Louisiana/Mississippi Societies for Clinical Laboratory Science, Invited Lecture, Annual Meeting2006
American Academy of Pediatrics, Member

Committee Service

SOHO/ASPHO Leukemia/lymphomas/lymphoproliferative disorders review group, Member2017 - 2019
Ambulatory Pediatric Champions Council, Member2013 - 2014
UMMC Cancer Institute Program Directors, Chair2012 - 2016
Batson PeriOperative Committee, Member2011 - Present
IRB Advisory Committee, Chair2011 - 2013
School Of Medicine - Faculty Appointments, Promotions, Chair2011 - 2013
School Of Medicine - Faculty Appointments, Promotions, Member2010 - Present
Ad Hoc Committee to Evaluate Research Conduct, Member2010 - 2012
Medical Center - Compliance, Member2008 - 2009
The University Hospitals and Clinics - Accreditation and Bylaws, Member2008 - 2009
Medical Center - Clinical Cancer Activities, Member2006 - Present
Medical Center - Cancer Institute Steering, Member2006 - 2008
SCHOOL OF MEDICINE-RESIDENCY REVIEW SUBCOMMITTEE, Chair2003 - 2007
THE UNIVERSITY HOSPITALS AND CLINICS-BLOOD TRANSFUSION, Chair2002 - 2004
THE UNIVERSITY HOSPITALS AND CLINICS-BLOOD TRANSFUSION, Member1999 - 2004
School Of Medicine - Graduate Medical Education, Member1996 - 2006
MEDICAL CENTER-CENTERS AND INSTITUTES, Member
MEDICAL CENTER-INSTITUTIONAL REVIEW BOARD 2, Member

Community Service

Jingle Bell Jog Committee, Member10/2011 - Present
Make A Wish, Board Member07/2010 - 05/2014
MS Leukemia and Lymphoma, Member, Physicians Advisiory Council07/2009 - 07/2012
Camp Rainbow Committee, Member and Camp Physician07/2000 - Present

Other Service

Children's Hospital Lab, Medical Director2014 - Present
Institutional Review Board, Member03/2012 - Present
Quality and Safety Task Force, Member09/2008 - Present
Medical Executive Committee, Chief of Staff07/2008 - 06/2009
University Physician Board Meeting, Member07/2008 - 06/2009
Medical Executive Committee, Vice Chair07/2007 - 06/2008
American Cancer Society-Institutional Research Grants Committee, Member2007 - 2009
Pediatric Executive Committee, Executive Vice Chair11/2006 - Present
Pediatric Special Hematology Laboratory, Medical Director11/2006 - 2012
Pediatric Executive Committee, Vice Chair for Education04/2002 - 11/2006
Stem Cell Transplant Program, Director, Pediatric Bone Marrow Transplant07/1994 - Present

Teaching Experience

Lead, Mentor Committee
Course Presenter, Pediatric Hematology Oncology M3 Ambulatory Rotation
Medicine, Course Presenter, Pediatric Hematology Oncology M4 Elective
Medicine, Member, Pediatric Hematology Oncology Fellowship Program Evaluation Committee - 2014

Fellows supervised

Pediatric Hematology Oncology, Training Faculty, 3 fellows supervised, Clinic and Wards07/2011 - 07/2020
Pediatric Hematology Oncology, Training Faculty, 2 fellows supervised07/2005 - 06/2010
Pediatric Hematology Oncology Fellowship, Program Director, 2 fellows supervised07/2005 - 06/2010

Residency Training

Pediatric Residency Program, Program Director1996 - 04/2006
Pediatric Residency Program, Attending Physician1994 - Present
Pediatric Hematology Oncology Fellowship, Attending Physician