Rathi V. Iyer

Rathi V. Iyer

PROFESSOR EMERITUS

Education

Children's Hospital of Michigan, Detroit, MI, MBBS, Fellowship in pediatric hematology/oncology1970
Detroit General Hospital and Sinai Hospital, Detroit, MBBS, Pediatric Residency1968
Worcester City Hospital, Worcester, Massachusetts, MBBS, Internship1967
Gandhi Hospital, MBBS, House Surgeon1966
Gandhi Medical College of Osmania University, MBBS, Medicine1966

Specialty Certification Licensure

UPIN, UPIN
Certification, American Bord of Pediatrics; Hem/Onc Subboard1976 - Present
Certification, American Board of Pediatrics1975 - Present
DEA, (DEA) Controlled Substance Registration Certificate10/2009 - 11/2012
Certification, PALS Provider, American Heart Association04/2010 - 04/2012
Licensure, Sate of Mississippi Medical License, Mississippi State Boad of Medical Licensure07/1973 - 06/2011

Current Positions

Director of Hematology Services, School of Medicine, Department of Pediatrics07/2007 - Present
Professor, School of Medicine, Department of Pediatrics07/1993 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Associate Professor, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics07/1986 - 06/1993
Assistant Professor, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics07/1973 - 06/1986

Sponsored Program Funding

Extramural, Public Health Surveillance for the Prevention of Complications of Bleeding and Clotting Disorders, CDC/The American Thrombosis and Hemostasis Network (ATHN)/HOG09/2012 - 09/2014
Extramural, TCD with Transfusions Changing to Hydroxyurea (TWiTCH), NIH/Baylor08/2012 - 07/2013
Extramural, MSDH Pediatric Sickle Cell/Hemoglobinopathy Program, Mississippi State Department of Health07/2012 - 06/2013
Extramural, MSDH Sickle Cell Case Management and Referral Services, Mississippi State Department of Health07/2012 - 06/2013
Extramural, Comprehensive Care in Hemophilia Patients, Department of Health, Education and Welfare Maternal Child Health06/2012 - 05/2013
Extramural, Prevention of Stroke after Stop, A Retrospective Chart Review (Post-Stop), Medical University of South Carolina06/2012 - 05/2013
Extramural, Blood Safety Surveillance Among Persons with Sickle Cell Disease in Mississippi, CDC05/2012 - 04/2014
Extramural, BABY HUG Follow-Up Study - II Clinical Sites, National Heart, Lung and Blood Institute01/2012 - 12/2016
Extramural, A Phase III Prospective, Randomized, Double-blind Placebo-controlled, Paralle-group, Multicenter Study of L-Glutamine Therapy for sickle Cell Anemia and Sickle B-Thalassemea, Emmaus Medical Inc11/2011 - 12/2012
Extramural, MSDH Pediatric Sickle Cell/Hemoglobinopathy Program, Mississippi State Department of Health07/2011 - 06/2012
Extramural, MSDH Sickle Cell Case Management and Referral Services, Mississippi State Department of Health07/2011 - 06/2012
Extramural, Comprehensive Care in Hemophilia Patients, Department of Health, Education and Welfare Maternal Child Health06/2011 - 05/2012
Extramural, Patent Foramen Ovale and Strokein Sickle Cell Disease (PFAST), Doris Duke Foundation/University of Texas Southwestern Medical Center03/2011 - 04/2013
Extramural, Children's Oncology Group Chairs Grant, National Childhood Cancer Foundation03/2011 - 02/2012
Extramural, ATHNdataquality.counts, American Thrombosis & Hemostatsis Network01/2011 - 01/2013
Extramural, Region IV South Program for the Prevention of the Complications of Hemophilia Through Hemophilia Treatment Centers, Centers for Disease Control and Prevention10/2010 - 09/2011
Extramural, Hemoglobinopathy surveillance Data and Education Services, Mississippi State Department of Health09/2010 - 07/2011
Extramural, MSDH Pediatric Sickle Cell/Hemoglobinopathy Program, Mississippi State Department of Health07/2010 - 06/2011
Extramural, MSDH/CMP Sickle Cell Care Coordination Service Program, Mississippi State Department of Health07/2010 - 06/2011
Extramural, A 5-year Prospective, Non-interventional Multicenter Registry in Sickle Cell Disease, Novartis Pharmaceuticals01/2010 - 12/2017
Extramural, A Phase 2 Randomized, Double-blind, Placebo-controlled Study of the Efficacy, Safety, and
Pharmacokinetics of GMI-1070, a Pan-Selectin Inhibitor, In Subjects Hospitalized For Sickle Cell
Vaso-occlusive Crisis
12/2009 - Present
Extramural, The Mechanisms of Race-Based Differences in Factor Viii Immunogenicity in Hemophilia, NIh/NHLBI/Sepulveda Research Corporation09/2009 - 08/2011
Extramural, Investigation of Gene Variants Associated with Resistance and Susceptibility to HIV-1 Exposed but Uninfected Individuals with Hemophilia A (CHAVI 014), NIH07/2009 - 06/2010
Extramural, Hemophilia Inhibitor Genetics Study (HIGS), Baxter Bio-Science/RHO Inc05/2009 - 09/2011
Extramural, Additional Centers for the Sickle Cell Disease Clinical Research Network Study #1: PROACTIVE Feasibility; Study #2 Improve, NIH /New England Research Institute01/2009 - 03/2011
Extramural, Stroke with Transfusions Changing to Hydorxyurea (SWiTCH), National Institute of Health08/2008 - 07/2010
Extramural, Iron Loading in Children with Sickle Cell Disease on Chronic Transfusion for Primary Stroke
Prevention (STOP/STOPII liver iron ancillary study). Protocol No. CICL670AUS06., Morehouse School of Medicine
01/2006 - 12/2006
Extramural, The HTRS Registry, Hemophilia and Thrombosis Research Society12/2004 - 09/2012
Extramural, Silent Cerebral Infarct Multi-Center Clinical Trial (SIT), National Institute of Health09/2003 - 12/2012
Extramural, Second Multicenter Hemophilia Cohort Study( MHCS-II ) Study of hepatitis C and complications
in hemophilia patients, The Viral Epidemiology Branch of NCI
01/2001 - 12/2005
Extramural, Pediatric Hydroxyurea Phase III Clinical Trial and Follow-up, National Heart, Lung and Blood Institute09/2000 - 06/2012
Extramural, Optimizing Primary Stroke Prevention in Children with Sickle Cell Anemia (STOP II), NIH/Medical College of Georgia08/2000 - 07/2005
Extramural, Intron A+ Ribavirin for Treatment of Patients with Inherited Coagulation Disorders and Chronic Hepatitis C, Schering Plough Corporation01/1999 - 12/2001
Extramural, Multicenter Study of Hip Coring Decompression of AVN in Sickle Cell Disease01/1998 - 12/2003
Extramural, Ryan White Care Act III - Outpatient Early Intervention Services with Respect to HIV Diseases, HRSA01/1991 - 12/1998

Publications

Journal Article

Thornburg C, Files B, Lue Z, Miller S, Kalpatthi R, Iyer R, Seaman P, Lebensburger J, Alvarez O, Thompson B, Ware R, Wang W: Impact of Hydroxyurea on clinical events in the
BABY HUG trial Blood August 22, 2012 blood-2012-03-419879. Impact of Hydroxyurea on clinical events in the
BABY HUG trial
Blood. August 22, 2012; blood-2012-03-419879.
2012
Ware RE, Helms RW, for the SWiTCH Investigators Stroke with Transfusions Changing to Hydroxyurea (SWiTCH) Blood. 2012;119:3925-39322012
Majumdar S, Ahmad N, Karlson C, Morris A, Iyer R Does weight reduction in haemophilia lead to a decrease in joint bleeds? Haemophilia. May 2012; Volume 18: issue 3, e82-e842012
DeBaun MR, Sarnaik SA, Rodeghier MJ, Minniti CP, Howard TH, Iyer RV, Inusa B, Telfer PT, Kirby-Allen M, Quinn CT, Bernaudin F, Airewele G, Woods GM, Panepinto JA, Fuh B, Kwiatkowski JK, King AA, Rhodes MM, Thompson AA, Heiny ME, Redding-Lallinger RC, Kirkham FJ, Sabio H, Gonzalez CE, Saccente SL, Kalinyak KA, Strouse JJ, Fixler JM, Gordon MO, Miller JP, Michael J. Noetzel MJ, Ichord RN, and Casella JF. Associated risk factors for silent cerebral infarcts in sickle cell anemia: low baseline hemoglobin, sex, and relative high systolic blood pressure. Blood 2012 119:3684-3690; published ahead of print November 17, 2011, doi:10.1182/blood-2011-05-3496212012
Styles L, Wager CG, Labotka RJ, Smith-Whitley K, Thompson AA, Lane PA, McMahon LE, Miller R, Roseff SD, Iyer RV, Hsu LL, Castro OL, Ataga KI, Onyekwere O, Okam M, Bellevue R, Miller ST; for the Sickle Cell Disease Clinical Research Network (SCDCRN). Refining the value of secretory phospholipase A(2) as a predictor of acute chest syndrome in sickle cell disease: results of a feasibility study (PROACTIVE). Br J Haematol. 2012, 157, 627-6362012
Ware RE, Schultz WH, Yovetich N, Mortier NA, Alvarez O, Hilliard L, Iyer RV, Miller ST, Rogers ZR, Scott JP, Waclawiw M, Helms RW Stroke with transfusions changing to hydroxyurea (SWiTCH): A phase III randomized clinical trial for treatment of children with sickle cell anemia, stroke, and iron overload. Pediatric Blood Cancer. 2011 Dec 1;57(6):1011-1017. doi: 10.1002/pbc.231452011
Lebensburger JD, Miller St, Howar TH, Casella JF, Brown RC, Lu M, Iyer RV, Sarnaik s, Rogers
ZR, Wang WC Influence of severity of anemia on clinical findings in infants with sickle cell
anemia: Analyses from the BABY HUG study.
Pediatric Blood Cancer. 2011; 59:675-678
2011
Wang W, Ware R, Miller S, Iyer R, Casella J, Minniti C, Rana S, Thornburg C, Rogers Z, Kalpatthi R, Barredo J, Brown RC, Sarnaik S, Howard T, Wynn L, Kutlar A, Armstrong D, Files B, Goldsmith J, Waclawiw M, Huange X, Thompson B, for the BABY HUG investigators Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG) The Lancet. 2011; 377, 9778, 1663 - 1672 doi:10.1016/S0140-6736(11)60355-3 Cite or Link Using DOI
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(11)60355-3/fulltext
2011
Rogers ZR, Wang WC, Luo Z, Iyer RV, Shalaby-Rana E, Dertinger SD, Shulkin BL, Miller JH, Files B, Lane PA, Thompson BW, Miller ST, Ware RE, and for the BABY HUG Investigators Biomarkers of splenic function in infants with sickle cell anemia: baseline data from the BABY HUG Trial BLOOD, 3 March 2011, Vol. 117, No. 9, pp. 2614-2617.
Prepublished online as a Blood First Edition Paper on January 7, 2011; DOI 10.1182/blood-2010-04-278747.
2011
Majumdar S, Ostrenga A, Latzman R , Payen C, Hunt Q, Morris A, Iyer R Pharmacoeconomic impact of obesity in
hemophilia in children with severe hemophilia in a single institution
Haemophilia, 2010 IN PRESS

Article first published online: 16 FEB 2011
DOI: 10.1111/j.1365-2516.2010.02462.x
2011
Latzman R, Majumdar S, Bigelow C, Elkin D, Smith M, Megason G, Srivastava P, and Iyer R Transitioning to adult care among adolescents with sickle cell disease: A transitioning clinic based on patient and caregiver concerns and needs International Journal of Child and Adolescent
Health, Special Edition, 2010;3(4):00-00.
2010
Majumdar S, Morris, A, Gordon C, Kermode JC, Forsythe A, Herrington B, Megason, GC, Iyer RV Alarmingly high prevalence of obesity in haemophilia in the state of Mississippi Haemophilia Vol 16: 3: pp 455-459, May 2010

DOI: 10.1111/j.1365-2516.2009.02187.x
2010
Majumdar S, Robertson Z, Robinson A, Starnes S, Iyer R, Megason GC: Outcome of hematopoietic cell transplantation in children with sickle cell disease, a single center’s experience. Bone Marrow Transplant. 2010; 45(5): 895-9002010
Thompson B, Miller S, Rogers Z, Rees R, Ware R, Waclawiw M, Iyer R, Casella J, Luchtman-Jones L, Rana S, Thornburg C, Kalpatthi R, Barredo J, Brown R, Sarnaik S, Howard T, Luck L, Wang W The pediatric hydroxyurea phase III clinical trial (BABY HUG): Challenges of study design Pediatric Blood and Cancer 54:250-255, February 2010

DOI: 10.1002/pbc.22269
2010
Pavlakis S, Rees R, Huang X, Brown R, Casella J, Iyer R, Kalpatthi R, Luden J, Miller S, Rogers Z, Thornburg C, Wang W, Adams R, for the BABY HUG Investigators Transcranial doppler ultrasonography (TCD) in infants with sickle cell anemia: Baseline data from the BABY HUG Trial Pediatric Blood & Cancer 54:256-259, February 2010

DOI: 10.1002/pbc.22282
2010
Miller ST, Wang WC, Iyer R, Rana S, Lane P, Ware RE, Li D, Rees RC, Clinical Trials & Surveys
Corporation, for the BABY UG investigators Urine concentrating ability in infants with sickle cell disease: Baseline data from the phase III trial of Hydroxyurea (BABY HUG) Pediatric Blood and Cancer 54:265-268
2010
The BABY HUG Investigators, Ware R, Rees R, Sarnaik S, Iyer R, Alvarez O, Casella J, Shulkin
B, Shalaby-Rana E, Strife C, Miller J, Lane P, Wang W, Miller S, Renal function in Infants with Sickle Cell Anemia: Baseline Data from the BABY HUG Trial The Journal of Pediatrics 156:66-70, January 2010

doi:10.1016/j.jpeds.2009.06.060
2010
Adamkiewicz T, Abboud M, Paley C, Olivieri N, Kirby-Allen M, Vichinsky E, Casella J, Alvarez O, Barredo J, Lee M, Iyer R, Kutlar A, McKie K, McKie V, Odo N, Gee B, Kwiatkowski J, Woods G, Coates T, Wang W, Adams R Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are non-linear, and are associated with iron load and liver injury Blood, 19 November 2009, Vol. 114, No. 21, pp. 4632-4638.

DOI 10.1182/blood-2009-02-203323.
2009
Majumdar S, Robertson Z, Robinson A, Starnes S, Iyer R, Megason G Outcome of hematopoietic cell transplantation in children with sickle cell disease, a single center’s experience: Bone Marrow Transplantation. 2009.244 doi:10.1038/bmt.2009.2442009
Viel KR, Ameri A, Abshire T, Iyer R, Watts R, Lutcher C, Channell C, Cole S, Fernstrom K, Nakaya S, Kasper C, Thompson A, Almasy A, Howard T Inhibitors of Factor VIII in Black Patients with Hemophilia New England Journal of Medicine 2009; 360:1618-272009
Thornburg CD, Rogers ZB, Wang W, Jeng M, Rana SR, Iyer RV, Faughman L, Marshall J, Hassen L, McDonald R, Rees RC Study Drug and Visit Adherence: Data from the BABY HUG Trial Blood. 2008; 112: 12752008
Jordan S, Hilker K, Stoppelbein L, Elkin D, Applegate H, Iyer R Nocturnal Enuresis and Psychosocial Problems in Pediatric Sickle Cell Disease and Sibling Controls Journal of Developmental and Behavioral Pediatrics Vol.26, No.6, December 20052005
Adamkiewicz T, Sarnaik S, Buchanan G, Iyer R, Miller S, Pegelow C, Rogers Z, Vichinsky E, Elliott J, Facklam R, O'Brien K, Schwartz B, Cannon M, Eckman J, Keyserling H, Sullivan K, Wong W, Wang W Invasive pneumococcal infections in children with sickle cell disease in the era of penicillin prophylaxis, antibiotic resistance, and 23-valent pneumococcal polysaccharide vaccination Journal of Pediatrics, Volume 143: 438-444, October 20032003
Dean D; Neumayr L; Kelly DM; Ballas SK; Kleman K; Robertson S; Iyer RV; Ware RE; Koshy M; Rackoff WR; Pegelow CH; Waldron P; Benjamin L; Vichinsky E Acute Chest Syndrome Study Group: Chlamydia pneumoniae and acute chest syndrome in patients with sickle cell disease Journal of Pediatric Hematology/Oncology 01-Jan-2003;25(1):46-552003
Malouf A, Hamrick-Turner J, Doherty M, Dhillon G, Iyer R, Smith MG Implementation of the STOP protocol for stroke prevention in sickle cell anemia utilizing duplex power doppler: a prospective study Radiology, 2001, 219: 359 - 3652001
Iyer R, Baliga R, Nagel RL, Brugnara C, Kirchner K, Hogan S, Steinberg MH Maximum urine concentrating ability and hematological indices in children with Hb SC disease: Effects of Hydroxyurea American Journal of Hematology, 2000 64:47-52
DOI: 10.1002/(SICI)1096-8652(200005)
2000
Neul S, Elkin TD, Applegate H, Griffin K, Bockewitz L, Iyer R, Smith MG, Mitchell T Developmental Concepts of Disease and Pain in Pediatric Sickle Cell Patients Children’s Health Care, 2003, 32(2), 81-101
Applegate H, Webb P, \Elkin TD, Neul S, Drabman R, Moll G, Jr, Pullen J, Smith MG, Iyer R, Megason G Improving Parent Participation at Pediatric Diabetes and Sickle Cell Appointments Using a Brief Intervention Children’s Health Care, 2003, 32(2), 125-136.

DOI: 10.1207/S15326888CHC3202_4

Abstracts

Rogers Z, Rees R, Files B, Iyer RV, Shulkin B, halaby-Rana E, Miller J, Dertinger S, Lane P, Wang W, Ware R and the BABY HUG Investigators Spleen Function in Infants with Sickle Cell Anemia: Baseline Data from the BABY HUG trial. Annual SCD Scientific Meeting, Ft. Lauderdale, FL2009
Wang WC, Rees RC, Miller ST, Brown RC, Casella JF, Iyer R, Kalpatthi R, Luden J, Rogers ZR, Thornburg C, Adams RJ, Pavlakis S for the BABY HUG Investigators Transcranial Doppler (TCD) ultrasonography in infants with sickle cell anemia: baseline data from the BABY HUG Trial 50th Annual Meeting, ASH, San Francisco CA, December 2008. Blood 2008:112:1436.2008
Ware RE, Rees RC, Sarnaik SA, Iyer RV, Alvarez OA, Casella JF, Shulkin BL, Shalaby-Rana E, Strife CF, Miller JH, Lane PA, Wang WC, Miller ST, and The BABY HUG Investigators Renal Function in Infants with Sickle Cell Anemia: Baseline Data from the BABY HUG Trial Blood. 2008; 112: 14142008
Miller S, Ware R, Kutlar A, Alvarez O, Iyer R, Sarnaik S, Rana S, Rogers Z, Lane P,Rees R, The BABY HUG Investigators Serum Cystatin-C Levels in Infants with Sickle Cell Anemia: Baseline Data from the BABY HUG Trial Blood (ASH Annual Meeting Abstracts), Nov 2008; 112: 4791.2008
Rogers ZR, Rees RC, Files B, Iyer RV, Shulkin BL, Shalaby-Rana E, Miller JH, Dertinger SD, Lane PA, Wang WC, Ware RE, The BABY HUG Investigators Spleen Function in Infants with Sickle Cell Anemia: Baseline Data from the BABY HUG Trial Blood. 2008; 112: 14162008
Thornburg CD, MD, Rogers ZB, Wang w, Jeng M, Rana SR, Iyer RV, Faughman L, Marshall J, Hassen L, McDonald R, Rees RC Study Drug and Visit Adherence: Data from the BABY HUG Trial Blood (ASH Annual Meeting Abstracts), Nov 2008; 112: 1275.2008
Miller ST, Wang WC, Iyer RV, Rana SR, Lane PA, Jr., Ware RE, Rees RC, The BABY HUG Investigators Sickle Cell Anemia: Baseline Data from the BABY HUG Trial Urine Concentrating Ability in Infants with Sickle Cell Anemia: Baseline Data from the BABY HUG Trial. Blood. 2008; 112:14132008
Majumdar S, Smith mg, Megason gc, Iyer RV, Kermode JC In vitro platelet activation in sickle cell disease under pathophysiological shear stress Presented 21st Annual ASPHO Meeting Abstracts, May 2008. Abstract 1275. Poster 143.2008
Majumdar S, Robertson Z, Robinson A, Starnes S, Iyer R, Megason G Outcome of Hematopoietic Cell Transplantation in Children with Sickle Cell Disease, a Single Center’s Experience Blood. 2007; 110: 11122007
Ware RE, McMurray MA, Schultz WH, Alvarez OA, Aygun B, Academic Community Standards for Chronic Transfusion Therapy in Children with Sickle Cell Anemia and Stroke Blood. 2006; 108:12132006
Howard TE, Viel KR, Fernstrom KM, Deshpande S, Afshin am, Showkat A, Channell C, Iyer RV, Watts RG, Lutcher C, Nakaya S, Kasper CK, Thompson AR, Abshire TC, Almasy L Allelically Mismatched Replacement Therapy Due to Common African-Restricted Haplotypes of the Factor (F)VIII Protein May Underlie the Increased Incidence of FVIII Inhibitors Observed in Hemophilia-A Patients of
African-Descent
Simultaneous Session: Coagulation and Hemophilia: Oral Session: Presented
at 48th Annual Meeting December, 2006. Blood (ASH Annual Meeting Abstracts), Nov 2006; 108: 765.
2006
Adamkiewicz T, Abboud MR, Barredo JC, Kirby-Allen M, Alvarez OA, Serum Ferritin in Children with Sickle Cell Disease on Chronic Transfusion: Measure of Iron Overload or End Organ Injury? STOP/STOP II Liver Iron Ancillary Study Blood, 2006; 108: 7912006
Adamkiewicz T, Abboud MR, Barredo JC, Kirby-Allen M, Alvarez OA, Casella JF, Iyer RV, McKie V, Woods GM, Kutlar A, Paley C, Peterson J, Rackoff E, Merelles-Pulcini , Dackiw E, Stegenga K, Odo N, Lou M, Adams R Serum Ferritin in Children with Sickle Cell Disease on Chronic Transfusion: Measure of Iron Overload or End Organ Injury? STOP/STOP II Liver Iron Ancillary Study Oral Session: Simultaneous Session: Hemolysis, Transfusion, and End Organ Dysfunction in Sickle Cell Disease: Presented at 48th Annual Meeting December, 2006. Blood (ASH Annual Meeting Abstracts), Nov 2006; 108: 791.2006
Neumayr L, Morris C, Wen A, Earles A, Robertson S, Abboud M, Ballas S, Browning I, Bellevue R, Daeschner C, Groncy P, Hume HA, Iyer RV, McMahon L, Moncino M, Orringer E, Swerdlow P,Waldron P, Ware R, Vichinsky E National Acute Chest Study Group (NACSG). Presented at the Oral Session: 47th ASH Annual Meeting, December 2005.2005
Adams RJ, Barredo J, Bonds DR, Brown C, Casella J, Daner L, Gerber AR, Iyer RV, Luden J, Miller S, Minniti C, Rana S, Rees R, Rogers Z, Toledano S, Wang W, Ware R, Zimmerman S TCD in Infants: A Report from the BABY HUG Trial Presented at the Poster Session: Basic Science and Clinical Practice in Blood Transfusion. 47th ASH Annual Meeting, December, 2005. Blood 2005; 106:280a2005
Rogers ZR, Thompson B, Ware RE, Wang WC, Iyer RV, Miller ST, Minniti C, Rana S, Barredo JC
Toledano S, Casella JF, Zimmerman SA, Files BA, Waclawiw M, Bonds DR Pharmacokinetics of hydroxyurea in young children with sickle cell anemia: a report from the BABY HUG Trial Blood. 2005;106:890a
2005
Howard T, Machiah D, Viel K, Channel C, Ameri A, Iyer R,
Watts R, Lutcher C, Davis J, Abshire T, Almasy L The Pharmacogenetics and Inhibitor Risk (PIR) Study: Establishing the Spectrum of Factor (F) VIII Gene (F8) in African-American Hemophilia A Patients Blood (ASH Annual Meeting Abstracts) 2005 106: Abstract 3207
2005
Ware RE, Miller ST, Rees RC, Iyer RV, Rogers ZR, Zimmerman SA, Minitti C, Barredo J, Rana S, Casella J, Toledano S, Dnner L, Thompson B, Wang WC Assessment of Renal Function in the Phase III Multi Center Hydroxyurea (BABY HUG) Trial For Infants With Sickle Cell Anemia Presented at the annual Sickle Cell Disease Clinical Research Meetings, August 29 – September 2, 2005.2005
Rogers ZR, Rees RR, Wang WC, Li D, Iyer RV, Rana S, Barredo JC, Casella JF, Driscoll C, Toledano S, Miller ST, Zimmerman SA, Miller JH, Shalaby-Ranha E, Dertinger S, Thompson B, Ware RE Evaluation of Splenic Function in Infants with Sickle Cell Anemia in the BABY HUG Trial Presented at the annual Sickle Cell Disease Clinical Research Meetings, August 29 – September 2, 2005.2005
Rogers ZR, Thompson B, Ware RE, Wang WC, Iyer RV, Miller ST, Minniti C, Rana S, Barredo JC, Toledano S, Zimmerman SA, Casella JF, Files BA, Waclawiw MA, Gerber AR, Bonds DR Pharmacokinetics of Hydroxyurea in Young Children with Sickle Cell Anemia: A Report from the BABY HUG Trial. Presented at the annual Sickle Cell Disease Clinical Research Meetings, August 29 – September 2, 2005.2005
Miller S, Barredo J,Brown CR, Bonds DR, Casella JF, Daner L, Rees R, Thompson B, Gerber AR, Iyer RV, Minniti C, Rana S, Rogers ZR, Toledano S, Wang W, Ware R, Zimmerman S Renal Concentrating Ability in Infants With Sickle Cell Anemia; Preliminary Data From BABY HUG, A Multicenter Trial Presented at the annual Sickle Cell Disease Clinical Research Meetings, August 29 – September 2, 2005.2005
Ware RE, Miller ST, Rees RC, Iyer RV, Rogers ZR, Zimmerman SA, Minitti C, Barredo J, Rana S, Casella JF, Toledano S, Li D, Thompson B, Wang WC Assessment of Renal Function in the Phase III Multi Center Hydroxyurea (BABY HUG) Trial For Infants With Sickle Cell Anemia Presented at the annual Sickle Cell Disease Clinical Research Meetings2005
Rogers ZR, Rees RR, Wang WC, Li D, Iyer RV, Rana S, Barredo JC, Casella JF, Driscoll C,
Toledano S, Miller ST, Zimmerman SA, Miller JH, Shalaby-Rana E, Dertinger SD, Thompson B,
Ware RE. Evaluation of splenic function in infants with sickle cell anemia in the BABY HUG Trial. Evaluation of splenic function in infants with sickle cell anemia in the BABY HUG Trial.
2005.Blood 2004;104:975a.
28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati OH, April 2005
2005
JF Casella, WC Wang, ZR Rogers, RC Rees, RV Iyer, S Rana, MC Driscoll, ST Miller, S Toledano, Barredo, SA Zimmerman, D Li, RE Ware, B Thompson Progress of the Multicenter Trial of Hydroxyurea in Infants with Sickle Cell Anemia (BABY HUG) and Assessment of Baseline Splenic and Renal Function ASPHO/PAS, Washington DC2005
Wang W, Rees R, Li, Rogers Z, Iyer R, Rana S, Barredo J, Casella J, Driscoll C, Toledano S,
Miller S, Zimmerman S, Shalaby-Rana,E Miller J, Thompson B, Ware R Evaluation of Renal Function By Glomerular Filtratio Rate (GFR) In Infants With Sickle Cell Anemia Presented 46th ASH Annual Meeting, San Diego, California
2004
Smith MG, Pullen J, Megason G, Mitchell T, Iyer R Streptococcus pneumoniae endophthalmitis in a patient with homozygous sickle cell disease 24th Annual Meeting of the National Sickle Cell Disease Program, Philadelphia, PA. April 8 - 12, 2000.2000
Mitchell TE, Smith MG, Iyer RV, Pullen DJ, Jones BP Zeroderma Pigmentosum presenting as squamous cell carcinoma of the eyelid in a patient with sickle cell disease 24th Annual meeting of the National Sickle Cell Disease Program, Philadelphia, PA. April 8 - 12, 2000.2000

Presentations

Poster Presentation, Comparison of Hematologic Measurements Between Local and Central Data from BABY HUG., ASPHO, ASPHO, Baltimore, MD04/2011
Platform Presentation, Effects of Hydroxyurea on Cerebral Blood Flow in Sickle Cell Anemia: Results From The BABU HIG Trial, ASPHO, ASPHO Baltimore MD04/2011
Poster Presentation, Febrile Episodes and Infections in Young Children with Sickle Cell Anemia (SCA), ASPHO, ASPHO BALTIMORE MD04/2011
Poster Presentation, The physiological and clinical effects of interrupting a treatment regimen of hydroxyurea in young children with sickle cell anemia (SCA)., ASH, ASH 2011 accepted as Poster Presentation.2011
Poster Presentation, In vitro platelet activation in sickle cell disease under pathophysiological shear stress, ASPHO, 21st Annual ASPHO Meeting05/2008
Poster Presentation, Academic Community Standards for Chronic Transfusion Therapy in Children with Sickle Cell Anemia and Stroke. Session Type: Poster Session, Board #341-I, 48th ASH Annual Meeting, Presented at the Poster Session: 48th ASH Annual Meeting December, 2006. Blood (ASH Annual Meeting Abstracts), Nov 2006; 108: 1213.11/2006
Poster Presentation, Evaluation of Splenic Function in Infants with Sickle Cell Anemia in the BABY HUG Trial, Presented, 46th ASH Annual Meeting, San Diego, California. December 4 – 7, 2004 (poster)12/2004
Poster Presentation, Developmental aspects of pain in children with sickle cell disease., Annual Meeting of the National Sickle Cell Group, New York, NY03/2001

Honors, Awards, and Recognition

Gold Award for Excellence in Research at UMMC, University of Mississippi Medical Center
UMC Captains Chair in appreciation of 20 years of service, University of Mississippi Medical Center
Hollaman Award for Outstanding Faculty, Department of Pediatrics, UMMC
letter award - Recognition for Teaching, Dept Chairman, Pediatrics, UMMC

Professional Membership and Service

Pediatric Blood and Cancer, Reviewer, Journal Article, Pediatric Blood and Cancer2012 - Present
Jackson State University, Adjunct Graduate Faculty2010 - Present
Writing Committee Sickle Cell Disease Clinical Research Network, Member2010 - Present
Publication Committee Sickle Cell Disease Clinical Research Network, Member2009 - Present
Writing Committee BABY HUG, Member2006 - Present
Publication Committee BABY HUG, Member, Publication Committee Conference Calls2004 - Present

Committee Service

The University Hospitals and Clinics - Blood Transfusion, Member2007 - Present

Community Service

Links UMMC Sickle Cell Fund, Member1999 - Present
Camp Sickle Stars, Camp Physician1998 - Present
MSDH Transition Advisory Committee, Member1998 - Present
Mississippi Childrens Medical Program, Member1997 - Present
Mississippi Sickle Cell Foundation, Medical Advisor1997 - Present
Misissippi Society of Oncology, Member1992 - Present
Mississippi Chapter, National Hemophilia Foundaton, Advisory Member1989 - Present
MSDH Newborn Screening for Hemoglobinopathy and Follow-up, Physician Member - Advisory1988 - Present
Genetic Advisory Comittee MS State Board of Health, Chairman1988 - 1991
Camp Rainbow, Camp Physician1984 - Present
Camp Rainbow for Children with Cancer committee, Member1984 - Present
Mississippi State Health Adviory Board for Sickle Cell Disease, Member1979 - 1981

Teaching Experience

Medicine, Lecture, Lecturer
Medicine, Lecture, Lecturer

Directed Student Learning

Dissertation Committee Member, An Investigation of Complimentary Alternative Methods in Conjunction with Pharmacologic Methods of Pain Control For Sickle Cell Disease Patients
Advised: Wendy Thompson
2009 - Present

Fellows supervised

Pediatric Hem/Onc Fellowship Program, A Faculty Supervisor, 5 fellows supervised07/1990 - Present

Residency Training

Pediatric Residency Program, Attending Physician1973 - Present