William B. Hillegass, MD, PhD
Professor
Department:
SPH-Dept of Data Science
Email:
whillegass@umc.edu
Work Phone:
(601) 815-3479
Biography
William Hillegass, MD, PhD is an Associate Professor of Data Science and Medicine. As a clinical investigator during 25 years of interventional cardiovascular practice, Dr. Hillegass employed a broad range of research methods including prospective randomized trials, observational studies, and comparative effectiveness analyses. His applied research includes antithrombotic therapies, acute coronary syndromes, peripheral vascular diseases, diabetes, and endovascular interventional therapies. His basic statistical methods research concerns indirect treatment comparison methods. He has focused on quantitative methods to verify the assumptions and validity of indirect treatment comparison methods such as network meta-analysis as well developed methods to improve robustness of indirect treatment effect estimators and hypothesis testing procedures. Additional methodological areas of research include individual patient data meta-analysis, retrospective harmonization of studies; databases, adaptive clinical trial designs, simulated clinical trials, bioinformatics for precision medicine, and health economic analyses.
Dr. Hillegass studied molecular genetics and econometrics as a Yale undergraduate. Medicine and clinical research design & application at Harvard Medical School, Harvard School Public Health, and Brigham and Womens Hospital. He trained in cardiovascular diseases and research at Duke University Medical Center and the Duke Clinical Research Institute. His PhD training in biostatistics was at the University of Alabama at Birmingham.
Education
University of Alabama at Birmingham, PhD, Biostatistics | 2017 |
Duke University Medical Center, General & Interventional Cardiovascular Fellowship, Cardiovascular Disease | 1994 |
Brigham and Womens Hospital, Internal Medicine Residency, Internal Medicine | 1990 |
Harvard School of Public Health, MPH, Translational Research | 1988 |
Harvard Medical School, MD, Medicine | 1988 |
Yale University, BA, Molecular Biophysics & Biochemistry | 1983 |
Yale University, BA, Economics & Political Science | 1983 |
Specialty Certification Licensure
Licensure, Mississippi Medical License | 02/2024 - Present |
Re-certification | 10/1995 - 10/2025 |
Certification, Diplomate, NBME | 07/1988 - Present |
Certification, Endovascular Medicine, ABVM | 07/2006 - Present |
Certification, Vascular Medicine, ABVM | 07/2006 - Present |
Re-certification, Interventional Cardiovascular, ABIM | 07/2011 - 07/2021 |
Certification, Interventional Cardiovascular, ABIM | 07/2000 - 07/2011 |
Re-certification, Internal Medicine, ABIM | 07/2011 - 07/2021 |
Re-certification, Internal Medicine, ABIM | 07/2002 - 07/2012 |
Certification, Internal Medicine, ABIM | 07/1992 - 07/2002 |
Current Positions
Professor, School of Population Health, Department of Medicine | 07/2024 - Present |
The University of Mississippi Medical Center Jackson, Mississippi 39216 |
Academic Appointments or Other Previous Appointments
Associate Professor, University of Mississippi Medical Center, School of Population Health, Department of Data Science | 2019 - 06/2024 |
Associate Professor, University of Alabama at Birmingham, School of Medicine | 03/2017 - 12/2018 |
Assistant Professor, University of Alabama at Birmingham, School of Population Health | 03/2017 - 12/2018 |
Fellow in Comparative Effectiveness Research, University of Alabama at Birmingham, School of Medicine | 07/2011 - 06/2013 |
Interventional Cardiologist/Researcher, Heart South Cardiovascular | 02/2011 - 03/2017 |
Associate Professor, University of Alabama at Birmingham, School of Medicine | 07/2005 - 09/2013 |
Assistant Professor, University of AAlabama at Birmingham, School of Medicine | 11/2000 - 07/2005 |
Director, Heart Group & Heartcare Health System | 08/1999 - 09/2000 |
Assistant Professor, Vanderbilt University Medical Center, School of Medicine | 1995 - 08/1999 |
Sponsored Program Funding
Extramural, Spirulina Oral Supplement for Enhancing Host Resilience to Virus Infection, NIH | 07/2024 - 06/2025 |
Extramural, UAB CTSA Renewal, NIH/NCATS | 05/2024 - 04/2031 |
Extramural, Reducing CV Risk in Rural MS, AHA | 04/2024 - 03/2028 |
Extramural, Mississippi Kidney Health Initiative, NIH | 04/2024 - 03/2029 |
Extramural, Mississippi Practice-Based Research Network EHR Enhancement to Advance Health, NIGMS/NIH | 11/2023 - 10/2024 |
Extramural, Teen Mom Study: Confirmatory Cluster Randomized Effectiveness Trial, NIH | 10/2023 - 06/2026 |
Extramural, Maternal Child Health Multicenter Grant, NIH | 09/2023 - 08/2030 |
Extramural, National COVID Cohort Collaborative (N3C) Supplement YR 4, NIH/NIGMS | 09/2023 - 08/2024 |
Extramural, Mechanisms of transition from acute to chronic pain in Non-Hispanic Black and White injury patients, NIH | 07/2023 - 06/2025 |
Extramural, National COVID Cohort Collaborative (N3C) Supplement YR 3, NIH/NIGMS | 08/2022 - 07/2023 |
Extramural, CLIF-VIP Gun Violence, NIH | 07/2022 - 06/2027 |
Extramural, Mississippi Center for Clinical and Translational Research, NIH/NIGMS | 10/2021 - 09/2026 |
Extramural, National COVID Cohort Collaborative (N3C) CTR Consortium YR 2, NIH/NIGMS | 08/2021 - 07/2022 |
Extramural, National COVID Cohort Collaborative (N3C) CTR Consortium, NIH/NIGMS | 07/2020 - 06/2021 |
Extramural, Individual- and area-level risk factors for COVID-19 disparities in Alabama, Mississippi, and Louisiana, University of Alabama at Birmingham | 06/2020 - 06/2022 |
Intramural, Innovative Children’s Healthcare Delivery: A Simulation Study, UMMC | 02/2020 - 01/2021 |
Extramural, Diabetic foot ulcer treatment trial, Corporate Sponsor | 01/2020 - Present |
Extramural, Simulation to guide implementation of telemedicine cardiorenal interventions to reduce health disparities., Health Resources and Services Administration | 01/2020 - 02/2022 |
Extramural, Mississippi Center for Clinical and Translational Research, NIH | 10/2016 - 09/2021 |
Publications
Letter | |
Hess CN, Peterson ED, Neely ML, Dai D, Hillegass WB, Krucoff MW, Kutcher MA, Messenger JC, Pancholy S, Piana RN, Rao SV, Response to letter regarding article, "The learning curve for transradial percutaneous coronary intervention among operators in the United States: a study from the National Cardiovascular Data Registry". Circulation, 2015 Feb 24;131(8):e358 | 2015 |
Xiang DC, Hillegass WB, Luo GX, He JX, Treatment of refractory iatrogenic femoral artery pseudoaneurysm with a vascular closure device. Journal of vascular and interventional radiology : JVIR, 2009 Dec;20(12):1639-40 | 2009 |
Multicenter Study | |
Garg PM, Rebentisch A, Zhang M, Ware J, Pippins M, Taylor C, Reddy K, Lewis T, Inder TE, Hillegass WB, Clinical impact of analgesic-sedative agents and peri-operative clinical status on white matter brain injury in preterm infants following surgical NEC. Journal of neonatal-perinatal medicine, 2023;16(3):527-537 | |
Journal Article | |
Anzalone AJ, Jackson LE, Singh N, Danila MI, Reisher E, Patel RC, Singh JA, National COVID Cohort Collaborative Consortium, Long-Term Mortality Following SARS-CoV-2 Infection in Rural Versus Urban Dwellers With Autoimmune or Inflammatory Rheumatic Disease: A Retrospective Cohort Analysis From the National COVID Cohort Collaborative. Arthritis care & research, 2025 Jan;77(1):143-155 | 2025 |
Anzalone AJ, Beasley WH, Murray K, Hillegass WB, Schissel M, Vest MT, Chapman SA, Horswell R, Miele L, Porterfield JZ, Bunnell HT, Price BS, Patrick S, Rosen CJ, Santangelo SL, McClay JC, Hodder SL, National COVID Cohort Collaborative (N3C) Consortium, Associations between COVID-19 therapies and outcomes in rural and urban America: A multisite, temporal analysis from the Alpha to Omicron SARS-CoV-2 variants. The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2025 Jan;41(1):e12857 | 2025 |
Garg PM, Pippin M, Zhang M, Ware J, Nelin S, Paschal J, Varshney N, Hillegass WB, Clinical Correlates of Moderate-to-Severe Bronchopulmonary Dysplasia in Preterm Infants following Surgical Necrotizing Enterocolitis. American journal of perinatology, 2024 Jul;41(10):1348-1358 | 2024 |
Zhang M, Hillegass WB, Yu X, Majumdar S, Daryl Pollard J, Jackson E, Knudson J, Wolfe D, Kato GJ, Maher JF, Mei H, Genetic variants and effect modifiers of QT interval prolongation in patients with sickle cell disease. Gene, 2024 Jan 10;890:147824 | 2024 |
Garg PM, Lett K, Ansari MAY, Cunningham H, Ware J, Pittman I, Riddick R, Sawaya D, Berch B, Morris M, Varshney N, Shenberger JS, Taylor C, Reddy K, Hillegass W, Outcomes by disease onset, sex, and intervention in neonates with SIP and surgical NEC. Pediatric research, 2024 Mar;95(4):1009-1021 | 2024 |
Sokol R, Walton M, Lee D, Seewald L, Del Toro VM, Farooqui M, Sallabank G, Zimmerman M, Edberg M, Wang Y, Zakrison T, Tung EL, Hillegass WB, Vearrier L, Zhang L, Kutcher ME, Blachman-Demner D, Carter PM, Advancing Science to Prevent Firearm Violence in Communities: A Process for Harmonizing Studies to Develop Research Infrastructure. Prevention science : the official journal of the Society for Prevention Research, 2024 Oct;25(7):1122-1132 | 2024 |
Garg PM, Riddick RA, Ansari MAY, Meilstrup AC, Zepponi D, Smith A, Mungan N, Shenberger J, Hillegass WB, Garg PP, Clinical and Growth Correlates of Retinopathy of Prematurity in Preterm Infants with Surgical Necrotizing Enterocolitis and Intestinal Perforation. American journal of perinatology, 2024 Nov;41(15):2152-2164 | 2024 |
Hillegass WB, Vascular closure after transfemoral transcatheter aortic valve replacement: Further randomized trials are justified. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2023 Apr;101(5):965-966 | 2023 |
Anzalone AJ, Horswell R, Hendricks BM, Chu S, Hillegass WB, Beasley WH, Harper JR, Kimble W, Rosen CJ, Miele L, McClay JC, Santangelo SL, Hodder SL, National COVID Cohort Collaborative (N3C) Consortium, Higher hospitalization and mortality rates among SARS-CoV-2-infected persons in rural America. The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2023 Jan;39(1):39-54 | 2023 |
Clemmer JS, Hillegass WB, Taylor EB, Antihypertensive effects of immunosuppressive therapy in autoimmune disease. Journal of human hypertension, 2023 Apr;37(4):300-306 | 2023 |
Dickens H, Rao U, Sarver D, Bruehl S, Kinney K, Karlson C, Grenn E, Kutcher M, Iwuchukwu C, Kyle A, Goodin B, Myers H, Nag S, Hillegass WB, Morris MC, Racial, Gender, and Neighborhood-Level Disparities in Pediatric Trauma Care. Journal of racial and ethnic health disparities, 2023 Jun;10(3):1006-1017 | 2023 |
Garg PM, Lett K, Ansari MAY, Pittman I, Riddick R, Varshney N, Morris M, Sawaya D, Taylor C, Reddy K, Porcelli P, Hillegass W, Postoperative Outcomes, and Growth and Brain Injury Outcomes in Spontaneous Intestinal Perforation vs Surgical Necrotizing Enterocolitis in Preterm Infants. Indian pediatrics, 2023 Nov 15;60(11):922-926 | 2023 |
Garg PM, Riddick R, Ansari MAY, Pittman I, Hillegass W, Clinical impact of timing of surgery on outcomes in preterm infants with surgical necrotizing enterocolitis. Research square, 2023 Jun 26; | 2023 |
Garg PM, Pittman IA, Ansari MAY, Yen CW, Riddick R, Jetton JG, South AM, Hillegass WB, Gestational age-specific clinical correlates of acute kidney injury in preterm infants with necrotizing enterocolitis. Pediatric research, 2023 Dec;94(6):2016-2025 | 2023 |
Lee M, Smolderen KG, Ionescu C, Hillegass WB, Romain G, Mena-Hurtado C, Lower extremity symptoms and ankle-brachial index screening as predictors of cardiovascular outcomes in Black adults. Vascular medicine (London, England), 2023 Jun;28(3):197-204 | 2023 |
Garg PM, Pittman I, Taylor C, Reddy K, Varshney N, Hillegass WB, Shetty A, Yi J, Inder T, Garg P, Clinical Correlates of Cerebellar Injury in Preterm Infants with Surgical Necrotizing Enterocolitis. Research square, 2023 Dec 11; | 2023 |
Winscott JG, Hillegass WB, Drug-coated balloon treatment of complex femoropopliteal disease yields favorable and durable outcomes at 5 years. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2022 Dec;100(7):1284-1285 | 2022 |
Winscott JG, Hillegass WB, Percutaneous coronary intervention in the polyvascular patient remains a high-risk procedure. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2022 Nov;100(5):747-748 | 2022 |
Garg PM, Middleton C, Zhang M, Paschal JL, Kurundkar AR, Sonani H, Varshney N, Hillegass WB, Clinical and histopathological correlates of intestinal repair in preterm infants following surgical necrotizing enterocolitis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022 Dec;35(26):10565-10576 | 2022 |
Garg PM, Paschal JL, Zhang M, Pippins M, Taylor C, Sanderson K, Reddy K, Askenazi D, Padbury JF, Hillegass WB, Clinical impact of severe acute kidney injury on post-operative and brain injury outcomes in preterm infants following surgical necrotizing enterocolitis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022 Dec;35(25):10124-10136 | 2022 |
Heindl B, Clarkson S, Parcha V, Dillon C, Narayan R, Usifo E, Hillegass W, Irvin MR, Arora P, Zhai G, Beasley M, Limdi N, Risk of Postdischarge Bleeding From Dual Antiplatelet Therapy After Percutaneous Coronary Intervention Among US Black and White Adults. Journal of the American Heart Association, 2022 Sep 20;11(18):e024412 | 2022 |
Ashley KE, Hillegass WB, Ticagrelor monotherapy after coronary stenting in patients requiring proton pump inhibitor and prolonged antiplatelet therapy. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2022 Jul;100(1):83-84 | 2022 |
Grenn E, Kutcher M, Hillegass WB, Iwuchukwu C, Kyle A, Bruehl S, Goodin B, Myers H, Rao U, Nag S, Kinney K, Dickens H, Morris MC, Social determinants of trauma care: Associations of race, insurance status, and place on opioid prescriptions, postdischarge referrals, and mortality. The journal of trauma and acute care surgery, 2022 May 1;92(5):897-905 | 2022 |
Garg PM, Paschal JL, Zhang M, Pippins M, Matthews A, Adams K, Taylor C, Reddy K, Inder TE, Hillegass WB, Brain injury in preterm infants with surgical necrotizing enterocolitis: clinical and bowel pathological correlates. Pediatric research, 2022 Apr;91(5):1182-1195 | 2022 |
Deer RR, Rock MA, Vasilevsky N, Carmody L, Rando H, Anzalone AJ, Basson MD, Bennett TD, Bergquist T, Boudreau EA, Bramante CT, Byrd JB, Callahan TJ, Chan LE, Chu H, Chute CG, Coleman BD, Davis HE, Gagnier J, Greene CS, Hillegass WB, Kavuluru R, Kimble WD, Koraishy FM, Köhler S, Liang C, Liu F, Liu H, Madhira V, Madlock-Brown CR, Matentzoglu N, Mazzotti DR, McMurry JA, McNair DS, Moffitt RA, Monteith TS, Parker AM, Perry MA, Pfaff E, Reese JT, Saltz J, Schuff RA, Solomonides AE, Solway J, Spratt H, Stein GS, Sule AA, Topaloglu U, Vavougios GD, Wang L, Haendel MA, Robinson PN, Characterizing Long COVID: Deep Phenotype of a Complex Condition. EBioMedicine, 2021 Dec;74:103722 | 2021 |
Bennett TD, Moffitt RA, Hajagos JG, Amor B, Anand A, Bissell MM, Bradwell KR, Bremer C, Byrd JB, Denham A, DeWitt PE, Gabriel D, Garibaldi BT, Girvin AT, Guinney J, Hill EL, Hong SS, Jimenez H, Kavuluru R, Kostka K, Lehmann HP, Levitt E, Mallipattu SK, Manna A, McMurry JA, Morris M, Muschelli J, Neumann AJ, Palchuk MB, Pfaff ER, Qian Z, Qureshi N, Russell S, Spratt H, Walden A, Williams AE, Wooldridge JT, Yoo YJ, Zhang XT, Zhu RL, Austin CP, Saltz JH, Gersing KR, Haendel MA, Chute CG, National COVID Cohort Collaborative (N3C) Consortium, Clinical Characterization and Prediction of Clinical Severity of SARS-CoV-2 Infection Among US Adults Using Data From the US National COVID Cohort Collaborative. JAMA network open, 2021 Jul 1;4(7):e2116901 | 2021 |
Leesar MA, Saif I, Hagood KL, Powell LC, Hillegass WB, Brott BC, A New Method to Optimize Stent Deployment by High-Definition Intravascular Ultrasound. The Journal of invasive cardiology, 2021 Jul;33(7):E532-E539 | 2021 |
Oates GR, Juarez LD, Horswell R, Chu S, Miele L, Fouad MN, Curry WA, Fort D, Hillegass WB, Danos DM, The Association Between Neighborhood Social Vulnerability and COVID-19 Testing, Positivity, and Incidence in Alabama and Louisiana. Journal of community health, 2021 Dec;46(6):1115-1123 | 2021 |
Tang SC, Capra CL, Ajebo GH, Meza-Junco J, Mairs S, Craft BS, Zhu X, Maihle N, Hillegass WB, Systemic toxicities of trastuzumab-emtansine predict tumor response in HER2+ metastatic breast cancer. International journal of cancer, 2021 Apr 12;149(4):909-16 | 2021 |
Langford AT, Akinyelure OP, Moore TL Jr, Howard G, Min YI, Hillegass WB, Bress AP, Tajeu GS, Butler M, Jaeger BC, Yano Y, Shimbo D, Ogedegbe G, Calhoun D, Booth JN 3rd, Muntner P Underutilization of Treatment for Black Adults With Apparent Treatment-Resistant Hypertension: JHS and the REGARDS Study. Hypertension (Dallas, Tex. : 1979) 2020 Sep 14: HYPERTENSIONAHA12014836 | 2020 |
Limdi NA, Cavallari LH, Lee CR, Hillegass WB, Holmes AM, Skaar TC, Pisu M, Dillon C, Beitelshees AL, Empey PE, Duarte JD, Diaby V, Gong Y, Johnson JA, Graves J, Garbett S, Zhou Z, Peterson JF, Implementing GeNomics In pracTicE (IGNITE) Network Pharmacogenetic Working Group (IGNITE-PGx), Cost-effectiveness of CYP2C19-guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data. The pharmacogenomics journal, 2020 Oct;20(5):724-735 | 2020 |
Langford AT, Akinyelure OP, Moore TL Jr, Howard G, Min YI, Hillegass WB, Bress AP, Tajeu GS, Butler M, Jaeger BC, Yano Y, Shimbo D, Ogedegbe G, Calhoun D, Booth JN 3rd, Muntner P, Underutilization of Treatment for Black Adults With Apparent Treatment-Resistant Hypertension: JHS and the REGARDS Study. Hypertension (Dallas, Tex. : 1979), 2020 Nov;76(5):1600-1607 | 2020 |
Cai A, Dillon C, Hillegass WB, Beasley M, Brott BC, Bittner VA, Perry GJ, Halade GV, Prabhu SD, Limdi NA, Risk of Major Adverse Cardiovascular Events and Major Hemorrhage Among White and Black Patients Undergoing Percutaneous Coronary Intervention. Journal of the American Heart Association, 2019 Nov 19;8(22):e012874 | 2019 |
Zoghbi GJ, Misra VK, Brott BC, Papapietro SE, Dai D, Wang TY, Klein LW, Messenger JC, Hillegass WB. Contemporary Percutaneous Coronary Intervention for Patients with Acute Myocardial Infarction and Left Main Culprit Lesions: A Report from the NCDR. Open J Cardiol Heart Dis. 1(3). OJCHD.000513.2018. | 2018 |
Cavallari LH, Lee CR, Beitelshees AL, Cooper-DeHoff RM, Duarte JD, Voora D, Kimmel SE, McDonough CW, Gong Y, Dave CV, Pratt VM, Alestock TD, Anderson RD, Alsip J, Ardati AK, Brott BC, Brown L, Chumnumwat S, Clare-Salzler MJ, Coons JC, Denny JC, Dillon C, Elsey AR, Hamadeh IS, Harada S, Hillegass WB, Hines L, Horenstein RB, Howell LA, Jeng LJB, Kelemen MD, Lee YM, Magvanjav O, Montasser M, Nelson DR, Nutescu EA, Nwaba DC, Pakyz RE, Palmer K, Peterson JF, Pollin TI, Quinn AH, Robinson SW, Schub J, Skaar TC, Smith DM, Sriramoju VB, Starostik P, Stys TP, Stevenson JM, Varunok N, Vesely MR, Wake DT, Weck KE, Weitzel KW, Wilke RA, Willig J, Zhao RY, Kreutz RP, Stouffer GA, Empey PE, Limdi NA, Shuldiner AR, Winterstein AG, Johnson JA, IGNITE Network, Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention. JACC. Cardiovascular interventions, 2018 Jan 22;11(2):181-191 | 2018 |
Hillegass WB, The many radial access learning curves. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017 Apr;89(5):865-866 | 2017 |
Ikeno F, Brooks MM, Nakagawa K, Kim MK, Kaneda H, Mitsutake Y, Vlachos HA, Schwartz L, Frye RL, Kelsey SF, Waseda K, Hlatky MA, BARI-2D Study Group, SYNTAX Score and Long-Term Outcomes: The BARI-2D Trial. Journal of the American College of Cardiology, 2017 Jan 31;69(4):395-403 | 2017 |
Harada S, Zhou Y, Duncan S, Armstead AR, Coshatt GM, Dillon C, Brott BC, Willig J, Alsip JA, Hillegass WB, Limdi NA, Precision Medicine at the University of Alabama at Birmingham: Laying the Foundational Processes Through Implementation of Genotype-Guided Antiplatelet Therapy. Clinical pharmacology and therapeutics, 2017 Sep;102(3):493-501 | 2017 |
Hillegass WB, Bradford GS, Risk guided use of the direct thrombin inhibitor bivalirudin: insights from recent trials and analyses. Journal of thoracic disease, 2016 Sep;8(9):E1034-E1040 | 2016 |
Hillegass WB, Limdi NA, Valvular Heart Disease and Acquired Type 2A von Willebrand Syndrome: The "Hemostatic" Waring Blender Syndrome. JAMA cardiology, 2016 May 1;1(2):205-6 | 2016 |
Hess CN, Peterson ED, Neely ML, Dai D, Hillegass WB, Krucoff MW, Kutcher MA, Messenger JC, Pancholy S, Piana RN, Rao SV, The learning curve for transradial percutaneous coronary intervention among operators in the United States: a study from the National Cardiovascular Data Registry. Circulation, 2014 Jun 3;129(22):2277-86 | 2014 |
Zhang J, Chen L, Delzell E, Muntner P, Hillegass WB, Safford MM, Millan IY, Crowson CS, Curtis JR, The association between inflammatory markers, serum lipids and the risk of cardiovascular events in patients with rheumatoid arthritis. Annals of the rheumatic diseases, 2014 Jul;73(7):1301-8 | 2014 |
Zhang J, Chen L, Delzell E, Muntner P, Hillegass WB, Safford MM, Millan IY, Crowson CS, Curtis JR, Republished: The association between inflammatory markers, serum lipids and the risk of cardiovascular events in patients with rheumatoid arthritis. Postgraduate medical journal, 2014 Dec;90(1070):722-9 | 2014 |
Feldman DN, Swaminathan RV, Kaltenbach LA, Baklanov DV, Kim LK, Wong SC, Minutello RM, Messenger JC, Moussa I, Garratt KN, Piana RN, Hillegass WB, Cohen MG, Gilchrist IC, Rao SV, Adoption of radial access and comparison of outcomes to femoral access in percutaneous coronary intervention: an updated report from the national cardiovascular data registry (2007-2012). Circulation, 2013 Jun 11;127(23):2295-306 | 2013 |
Hillegass WB, Patel MR, Klein LW, Gurm HS, Brennan JM, Anstrom KJ, Dai D, Eisenstein EL, Peterson ED, Messenger JC, Douglas PS, Long-term outcomes of older diabetic patients after percutaneous coronary stenting in the United States: a report from the National Cardiovascular Data Registry, 2004 to 2008. Journal of the American College of Cardiology, 2012 Dec 4;60(22):2280-9 | 2012 |
Brennan JM, Dai D, Patel MR, Rao SV, Armstrong EJ, Messenger JC, Curtis JP, Shunk KA, Anstrom KJ, Eisenstein EL, Weintraub WS, Peterson ED, Douglas PS, Hillegass WB, Characteristics and long-term outcomes of percutaneous revascularization of unprotected left main coronary artery stenosis in the United States: a report from the National Cardiovascular Data Registry, 2004 to 2008. Journal of the American College of Cardiology, 2012 Feb 14;59(7):648-54 | 2012 |
Klein LW, Ho KK, Singh M, Anderson HV, Hillegass WB, Uretsky BF, Chambers C, Rao SV, Reilly J, Weiner BH, Kern M, Bailey S, Society of Cardiovascular Angiography and Interventions, Quality assessment and improvement in interventional cardiology: a Position Statement of the Society of Cardiovascular Angiography and Interventions, Part II: public reporting and risk adjustment. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011 Oct 1;78(4):493-502 | 2011 |
Klein LW, Uretsky BF, Chambers C, Anderson HV, Hillegass WB, Singh M, Ho KK, Rao SV, Reilly J, Weiner BH, Kern M, Bailey S, Society of Cardiovascular Angiography and Interventions, Quality assessment and improvement in interventional cardiology: a position statement of the Society of Cardiovascular Angiography and Interventions, part 1: standards for quality assessment and improvement in interventional cardiology. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011 Jun 1;77(7):927-35 | 2011 |
Brooks MM, Chung SC, Helmy T, Hillegass WB, Escobedo J, Melsop KA, Massaro EM, McBane RD, Hyde P, Hlatky MA, Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Study Group, Health status after treatment for coronary artery disease and type 2 diabetes mellitus in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial. Circulation, 2010 Oct 26;122(17):1690-9 | 2010 |
Hlatky MA, Chung SC, Escobedo J, Hillegass WB, Melsop K, Rogers W, Brooks MM, BARI 2D Study Group, The effect of obesity on quality of life in patients with diabetes and coronary artery disease. American heart journal, 2010 Feb;159(2):292-300 | 2010 |
Mehta RH, Ou FS, Peterson ED, Shaw RE, Hillegass WB Jr, Rumsfeld JS, Roe MT, American College of Cardiology-National Cardiovascular Database Registry Investigators, Clinical significance of post-procedural TIMI flow in patients with cardiogenic shock undergoing primary percutaneous coronary intervention. JACC. Cardiovascular interventions, 2009 Jan;2(1):56-64 | 2009 |
Zoghbi GJ, Goyal M, Hage F, Meyers RP, Papapietro SE, Brott BC, Misra VK, Iskandrian AE, Hillegass WB, Pretreatment with nitroprusside for microcirculatory protection in saphenous vein graft interventions. The Journal of invasive cardiology, 2009 Feb;21(2):34-9 | 2009 |
BARI 2D Study Group, Frye RL, August P, Brooks MM, Hardison RM, Kelsey SF, MacGregor JM, Orchard TJ, Chaitman BR, Genuth SM, Goldberg SH, Hlatky MA, Jones TL, Molitch ME, Nesto RW, Sako EY, Sobel BE, A randomized trial of therapies for type 2 diabetes and coronary artery disease. The New England journal of medicine, 2009 Jun 11;360(24):2503-15 | 2009 |
Koshy SK, Kleiman NS, George LK, Misra V, Hillegass WB, Brott BC, Vascular changes and black hole phenomenon after coronary brachytherapy: a pathologically distinct entity. The Journal of invasive cardiology, 2008 Oct;20(10):560-2 | 2008 |
Bypass Angioplasty Revascularization Investigation 2 Diabetes Study Group, Baseline characteristics of patients with diabetes and coronary artery disease enrolled in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial. American heart journal, 2008 Sep;156(3):528-536, 536.e1-5 | 2008 |
Hillegass WB, Gupta H, Katragadda R, Knoblauch J, Coghlan C, Misra VK, Ruptured giant right coronary artery aneurysm percutaneously plugged. The Journal of invasive cardiology, 2007 Mar;19(3):139-41 | 2007 |
Rajdev S, Hillegass WB, Misra V, First human case description of TandemHeart-assisted high-risk percutaneous balloon aortic valvuloplasty using bivalirudin anticoagulation. The Journal of invasive cardiology, 2007 Jan;19(1):E5-8 | 2007 |
Brott BC, Anayiotos AS, Chapman GD, Anderson PG, Hillegass WB, Severe, diffuse coronary artery spasm after drug-eluting stent placement. The Journal of invasive cardiology, 2006 Dec;18(12):584-92 | 2006 |
Hillegass WB, Goyal M, Misra VK, Jordan WD, Cypher drug-eluting stent treatment of tibioperoneal obstructive disease: a case report. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2005 Feb;64(2):237-41 | 2005 |
Zoghbi GJ, Misra VK, Chapman GD, Hillegass WB, Brott BC, Aqel RA, Bourge RC, Long-term follow-up of brachytherapy for treatment of allograft in-stent restenosis. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2004 Feb;61(2):217-21 | 2004 |
Hillegass WB, Zoghbi GJ, Pandey A, Misra VK, Chapman GD, Brott BC, Treatment of in-stent restenosis in a gastroepiploic artery coronary bypass graft with brachytherapy. The Journal of invasive cardiology, 2003 Nov;15(11):677-80 | 2003 |
Hillegass WB, Brott BC, Chapman GD, Phillips HR, Stack RS, Tcheng JE, Califf RM, Relationship between activated clotting time during percutaneous intervention and subsequent bleeding complications. American heart journal, 2002 Sep;144(3):501-7 | 2002 |
Hillegass WB, Dean NA, Liao L, Rhinehart RG, Myers PR, Treatment of no-reflow and impaired flow with the nitric oxide donor nitroprusside following percutaneous coronary interventions: initial human clinical experience. Journal of the American College of Cardiology, 2001 Apr;37(5):1335-43 | 2001 |
Hillegass WB, Newman AR, Raco DL, Glycoprotein IIb/IIIa receptor therapy in percutaneous coronary intervention and non-ST-segment elevation acute coronary syndromes. Estimating the economic implications. PharmacoEconomics, 2001 Jan;19(1):41-55 | 2001 |
Singh M, Reeder GS, Ohman EM, Mathew V, Hillegass WB, Anderson RD, Gallup DS, Garratt KN, Holmes DR Jr, Does the presence of thrombus seen on a coronary angiogram affect the outcome after percutaneous coronary angioplasty? An Angiographic Trials Pool data experience. Journal of the American College of Cardiology, 2001 Sep;38(3):624-30 | 2001 |
Hillegass WB, Newman AR, Raco DL, Economic issues in glycoprotein IIb/IIIa receptor therapy. American heart journal, 1999 Jul;138(1 Pt 2):S24-32 | 1999 |
Goklaney AK, Murphy JD, Hillegass WB Jr, Abciximab therapy in percutaneous intervention: economic issues in the United States. European heart journal, 1998 Apr;19 Suppl D:D52-8 | 1998 |
Ferguson JJ, Kereiakes DJ, Adgey AA, Fox KA, Hillegass WB Jr, Pfisterer M, Vassanelli C, Safe use of platelet GP IIb/IIIa inhibitors. European heart journal, 1998 Apr;19 Suppl D:D40-51 | 1998 |
Goklaney AK, Murphy JD, Hillegass WB Jr, Abciximab therapy in percutaneous intervention: economic issues in the United States. American heart journal, 1998 Apr;135(4):S90-7 | 1998 |
Ferguson JJ, Kereiakes DJ, Adgey AA, Fox KA, Hillegass WB Jr, Pfisterer M, Vassanelli C, Safe use of platelet GP IIb/IIIa inhibitors. American heart journal, 1998 Apr;135(4):S77-89 | 1998 |
Agirbasli M, Hillegass WB Jr, Chapman GD, Brott BC, Stent procedure complicated by thrombus formation distal to the lesion within a muscle bridge. Catheterization and cardiovascular diagnosis, 1998 Jan;43(1):73-6 | 1998 |
Califf RM, Tardiff BE, Pieper KS, Hillegass WB, Use of calcium channel antagonists in myocardial revascularization procedures. The American journal of cardiology, 1996 Jun 20;77(16):26D-31D | 1996 |
Narins CR, Hillegass WB Jr, Nelson CL, Tcheng JE, Harrington RA, Phillips HR, Stack RS, Califf RM, Relation between activated clotting time during angioplasty and abrupt closure. Circulation, 1996 Feb 15;93(4):667-71 | 1996 |
Hillegass WB, Jollis JG, Granger CB, Ohman EM, Califf RM, Mark DB, Intracranial hemorrhage risk and new thrombolytic therapies in acute myocardial infarction. The American journal of cardiology, 1994 Mar 1;73(7):444-9 | 1994 |
Boehme AK, Pamboukian SV, George JF, Beasley TM, Kirklin JK, Tallaj J, Dillon C, Levitan EB, Griffin R, McGwin G Jr, Hillegass WB, Limdi NA, Anticoagulation Control in Patients With Ventricular Assist Devices. ASAIO journal (American Society for Artificial Internal Organs : 1992), 2017 Nov Dec;63(6):759-765 | |
Hillegass WB, Brott BC, Dobbs JC, Papapietro SE, Misra VK, Zoghbi GJ, Oral antiplatelet therapy in diabetes mellitus and the role of prasugrel: an overview. Vascular health and risk management, 2011;7:445-59 | |
Hillegass WB, The Economics of IIb/IIIa Therapy. The Journal of invasive cardiology, 1996;8 Suppl B:30B-33B | |
Moradi H, Bunnell HT, Price BS, Khodaverdi M, Vest MT, Porterfield JZ, Anzalone AJ, Santangelo SL, Kimble W, Harper J, Hillegass WB, Hodder SL, National COVID Cohort Collaborative (N3C) Consortium, Assessing the effects of therapeutic combinations on SARS-CoV-2 infected patient outcomes: A big data approach. PloS one, 2023;18(3):e0282587 | |
Anzalone AJ, Sun J, Vinson AJ, Beasley WH, Hillegass WB, Murray K, Hendricks BM, Haendel M, Geary CR, Bailey KL, Hanson CK, Miele L, Horswell R, McMurry JA, Porterfield JZ, Vest MT, Bunnell HT, Harper JR, Price BS, Santangelo SL, Rosen CJ, McClay JC, Hodder SL, National COVID Cohort Collaborative (N3C) Consortium, Community risks for SARS-CoV-2 infection among fully vaccinated US adults by rurality: A retrospective cohort study from the National COVID Cohort Collaborative. PloS one, 2023;18(1):e0279968 | |
Garg PM, Denton MX, Talluri R, Ostrander MM, Middleton C, Sonani H, Varshney N, Hillegass WB, Clinical determinants and impact of hemorrhagic lesions on intestinal pathology in preterm infants with surgical necrotizing enterocolitis. Journal of neonatal-perinatal medicine, 2023;16(1):119-128 | |
Garg PM, Paschal JL, Ansari MAY, Sonani H, Grey C, Chan S, Varshney N, Hillegass W, Clinical outcomes and gestational age based prediction of pneumatosis intestinalis in preterm infants with necrotizing enterocolitis. Journal of neonatal-perinatal medicine, 2022;15(4):803-812 | |
Senitko M, Oberg CL, Abraham GE, Hillegass WB, Akhtar I, Folch E, Microwave Ablation for Malignant Central Airway Obstruction: A Pilot Study. Respiration; international review of thoracic diseases, 2022;101(7):666-674 | |
Garg PM, Pittman I, Yi J, Shetty A, Taylor C, Reddy K, Inder TE, Varshney N, Hillegass WB, Garg PP, Clinical correlates of cerebellar injury in preterm infants with surgical necrotizing enterocolitis. Journal of neonatal-perinatal medicine, 2024;17(5):705-716 | |
Garg PM, Denton MX, Talluri R, Ansari MAY, Riddick R, Ostrander MM, McDonald AG, Premkumar MH, Hillegass WB, Garg PP, Clinical determinants of intestinal failure and death in preterm infants with surgical necrotizing enterocolitis. Journal of neonatal-perinatal medicine, 2023;16(4):589-596 | |
Clinical Trial | |
Tolleson TR, O'Shea JC, Bittl JA, Hillegass WB, Williams KA, Levine G, Harrington RA, Tcheng JE, Relationship between heparin anticoagulation and clinical outcomes in coronary stent intervention: observations from the ESPRIT trial. Journal of the American College of Cardiology, 2003 Feb 5;41(3):386-93 | 2003 |
Lederman RJ, Mendelsohn FO, Anderson RD, Saucedo JF, Tenaglia AN, Hermiller JB, Hillegass WB, Rocha-Singh K, Moon TE, Whitehouse MJ, Annex BH, TRAFFIC Investigators, Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial. Lancet (London, England), 2002 Jun 15;359(9323):2053-8 | 2002 |
Hillegass WB, Ohman EM, Leimberger JD, Califf RM, A meta-analysis of randomized trials of calcium antagonists to reduce restenosis after coronary angioplasty. The American journal of cardiology, 1994 May 1;73(12):835-9 | 1994 |
Comment | |
Brott BC, Hillegass WB, ACP Journal Club: 24- and 6-month dual antiplatelet therapy after coronary stenting did not differ for clinical outcomes. Annals of internal medicine, 2012 Aug 21;157(4):JC2-9 | 2012 |
Hillegass WB, A full toolbox fixes the roadblocks. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011 Apr 1;77(5):759-60 | 2011 |
Hillegass WB, ACP Journal Club. Review: Third-generation P2Y12 inhibitors reduce mortality after PCI more than clopidogrel. Annals of internal medicine, 2011 Mar 15;154(6):JC3-6 | 2011 |
Hillegass WB, DES in SVGs: safe and at least short-term effective. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011 Feb 15;77(3):356-7 | 2011 |
Hillegass WB, Drug-eluting or bare metal stents for diabetics: clinical judgment still wins. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010 Oct 1;76(4):482-3 | 2010 |
Hillegass WB, The Holy Grail for DES: does efficacy translate into real world effectiveness? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010 Sep 1;76(3):381-2 | 2010 |
Hillegass WB, Which DES for diabetics? Round 1: A draw. Round 2: Everolimus leading? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010 Jul 1;76(1):58-9 | 2010 |
Hillegass WB, Brott BC, ACP Journal Club. Prasugrel prevented ischemic events compared with clopidogrel in patients having PCI for STEMI. Annals of internal medicine, 2009 Jun 16;150(12):JC6-10 | 2009 |
Hillegass WB, A third dimension to uncloud the funnel plot of operator quality. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009 Apr 1;73(5):595-6 | 2009 |
Hillegass WB, Brott BC, Prasugrel reduced ischemic outcomes more than did clopidogrel in patients receiving stents for ACS. ACP journal club, 2008 Sep 16;149(3):12 | 2008 |
Brott BC, Hillegass WB, Review: late percutaneous coronary intervention after AMI improves survival more than optimal medical therapy. ACP journal club, 2008 Jul;149(1):6 | 2008 |
Hillegass WB, DES in saphenous bypass grafts: A treatment in vain? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008 Jul 1;72(1):21-2 | 2008 |
Hillegass WB, PCI with bivalirudin and provisional GP IIb/IIIa inhibition is more cost-effective than heparin plus routine GP IIb/IIIa inhibition. Commentary. Evidence-based cardiovascular medicine, 2005 Mar;9(1):68-71 | 2005 |
Hillegass WB, Dorfman TA, Aspirin was cost-effective for primary prevention of cardiovascular events in older women at moderate risk. ACP journal club, 2007 Jul-Aug;147(1):24 | |
Hillegass WB, Brott BC, Urgent revascularization with PCI was more cost-effective than CABG in medically refractory, high-risk myocardial ischemia. ACP journal club, 2007 Mar-Apr;146(2):49 | |
Suarez A, Rajdev S, Hillegass WB, Review: evidence supporting reduced death and reinfarction by percutaneous coronary intervention after thrombolysis is inconclusive. ACP journal club, 2006 May-Jun;144(3):60-1 | |
Suarez A, Rajdev S, Hillegass WB, Rescue angioplasty reduced cardiovascular and cerebrovascular outcomes in acute MI after failed thrombolytic therapy. ACP journal club, 2006 May-Jun;144(3):60-1 | |
Hillegass WB, McElderry HT Jr, Prophylactic implantable cardioverter-defibrillators increased life expectancy with an acceptable cost-effectiveness ratio. ACP journal club, 2006 Mar-Apr;144(2):52 | |
Hillegass WB, Brott BC, Invasive strategy within 24 hours of thrombolysis reduced death, nonfatal reinfarction, and ischemia-induced revascularization in STEMI. ACP journal club, 2005 Mar-Apr;142(2):38 | |
Hillegass WB, Alam GK, High-dose atorvastatin was superior to standard-dose pravastatin for reducing death or major cardiovascular events in acute coronary syndromes. ACP journal club, 2004 Sep-Oct;141(2):33 | |
Hillegass WB, Brott BC, Review: low-molecular-weight heparin is effective and safe in the acute coronary syndromes. ACP journal club, 2003 Nov-Dec;139(3):58 | |
Brott BC, Hillegass WB, An early invasive strategy reduced death, myocardial infarction, and hospital readmissions at 2 years in unstable CAD. ACP journal club, 2003 Sep-Oct;139(2):30 | |
Hillegass WB, Brott BC, An interventional strategy was better than a conservative strategy in unstable angina or non-ST-elevation MI. ACP journal club, 2003 Mar-Apr;138(2):32 | |
Hillegass WB, Epstein AE, Cardiac resynchronization was effective for moderate-to-severe heart failure with intraventricular conduction delay. ACP journal club, 2002 Nov-Dec;137(3):82 | |
Editorial | |
Winscott JG, Hillegass WB, Successfully treating the common femoral artery "no go zone" with directional atherectomy plus antirestenotic therapy (DAART). Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2022 Mar;99(4):1317-1318 | 2022 |
Winscott JG, Hillegass WB, Covered stents favored in complex aortoiliac disease. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021 Nov 1;98(5):938-939 | 2021 |
Hillegass WB, Diabetes and everolimus eluting bioresorbable poly-L-lactide vascular scaffolds for coronary artery disease: Dead-end or some path forward? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021 Oct;98(4):721-722 | 2021 |
Winscott JG, Hillegass WB, Critical limb ischemia in the end stage renal disease patient: Some next steps. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021 Aug 1;98(2):308-309 | 2021 |
Ashley KE, Hillegass WB, Genotype-guided antiplatelet therapy for acute coronary syndrome percutaneous coronary intervention patients: A new standard of care? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021 Apr 1;97(5):795-796 | 2021 |
Ashley KE, Hillegass WB, Antiplatelet therapy regimen and duration after percutaneous coronary intervention: Combining prediction scores with clinical judgment. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021 Mar;97(4):579-580 | 2021 |
Winscott JG, Hillegass WB, Everolimus eluting bioresorbable vascular scaffolds for infrapopliteal critical limb ischemia: Moving beyond grasping at metal straws. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021 Jan 1;97(1):150-151 | 2021 |
Ashley KE, Hillegass WB, Insulin-treated diabetes mellitus: An actionable risk factor and marker after percutaneous coronary intervention. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Aug;96(2):309-310 | 2020 |
Winscott JG, Hillegass WB, A step forward in predicting anterograde crossing success for infrapopliteal chronic total occlusions. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Mar 1;95(4):756-757 | 2020 |
Winscott JG, Hillegass WB, Prior probability of significant obstructive arterial disease in the contralateral lower extremity. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Feb;95(2):307-308 | 2020 |
Ashley KE, Hillegass WB, Ticagrelor monotherapy: When is mono-antiplatelet therapy (MAPT) equivalent or better? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Dec;96(7):1379-1380 | 2020 |
Ashley KE, Hillegass WB, Radial access and risk guided use of bivalirudin? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Nov;96(6):1249-1250 | 2020 |
Winscott JG, Hillegass WB, Safety and efficacy of paclitaxel drug-coated balloon treatment of femoropopliteal claudicants: Data and analytic methods matter. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Nov;96(5):1100-1101 | 2020 |
Winscott JG, Hillegass WB, A step toward physiologically guided chronic limb-threatening ischemia intervention. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Oct 1;96(4):913-914 | 2020 |
Ashley KE, Hillegass WB, Clopidogrel pretreatment may reduce early acquired thrombocytopenia after transcatheter aortic valve replacement (TAVR). Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019 Nov 15;94(6):818-819 | 2019 |
Ashley KE, Hillegass WB, Costs of postoperative delirium with transcatheter aortic valve replacement: Improved yet still present. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019 May 1;93(6):1137 | 2019 |
Chatterjee A, Leesar MA, Hillegass WB, Intravascular ultrasound of normal left main arteries: Insights for stent optimization and standardization. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019 Feb 1;93(2):239-240 | 2019 |
Chatterjee A, Hillegass WB, Patent foramen ovale closure for cryptogenic stroke: Effective, but only in select patients. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2018 Jul;92(1):174-175 | 2018 |
Chatterjee A, Hillegass WB, Embolic stroke of undetermined source and patent foramen ovale closure: Practice insights from meta-analysis? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2018 Nov 15;92(6):1161-1162 | 2018 |
Chatterjee A, Hillegass WB, "Expanding the frame" for valve-in-valve therapy in small bioprostheses: Encouraging signs for the road ahead. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2018 Sep 1;92(3):555-556 | 2018 |
Chatterjee A, Hillegass WB, Surgical aortic valve replacement and transcatheter aortic valve implantation for severe aortic stenosis: Equipoise remains a tenable assumption. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2018 Aug 1;92(2):431-432 | 2018 |
Xie R, Hillegass WB, Long-term survival prospects of patients undergoing percutaneous coronary intervention: Envisioning the future. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2018 Mar 1;91(4):696 | 2018 |
Chatterjee A, Hillegass WB, The promise of effective P2Y(12) platelet receptor pretreatment: Not crushed yet. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2018 Feb 1;91(2):251-252 | 2018 |
Chatterjee A, Hillegass WB, Patient preference: An important emerging factor in operator access site selection. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2018 Jan 1;91(1):25-26 | 2018 |
Chatterjee A, Hillegass WB, Individualizing dual antiplatelet therapy duration: Prediction tools, genomics, and clinical judgment. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017 Jul;90(1):38 | 2017 |
Chatterjee A, Hillegass WB, Length and pressure matter: Expediting evidence-based progress in femoropoliteal intervention. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017 Jun 1;89(7):1257-1258 | 2017 |
Chatterjee A, Hillegass WB, Unprotected Left Main Disease and Percutaneous Intervention: A Prototype for Precision Medicine. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017 Jan;89(1):11-12 | 2017 |
Segrest JH, Hillegass WB, Radial Access Optimization in the Nascent Post-Adoption Era. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016 Dec;88(7):1044-1045 | 2016 |
Sarraf M, Hillegass W, Routine invasive evaluation in non ST elevation myocardial infarction (NSTEMI-ACS): Optimizing best. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016 Nov;88(5):775-776 | 2016 |
Hillegass WB, Insulin-treated diabetes mellitus: An important, actionable risk marker after coronary stenting. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016 Jan 1;87(1):63-4 | 2016 |
Hillegass WB, End of the bare metal stent era? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016 Jul;88(1):49-50 | 2016 |
Hillegass WB, Risk-guided use of the direct thrombin inhibitor bivalirudin. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016 Feb 15;87(3):401-2 | 2016 |
Hillegass WB, Diabetes is not sufficient justification for IIb/IIIa use in percutaneous coronary intervention. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015 Sep;86(3):376-7 | 2015 |
Segrest JH, Hillegass WB, Renal artery stenting: patient selection post-CORAL. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015 Aug;86(2):310-1 | 2015 |
Hillegass WB, Brott BC, Obesity and percutaneous coronary intervention outcomes: beware the extremes. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015 May;85(6):959-60 | 2015 |
Hillegass WB, Brott BC, Percutaneous coronary intervention: ever closer to real world silver bullets!? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015 Apr;85(5):807-8 | 2015 |
Hillegass WB, Brott BC, Can femoral access bleeding outcomes be improved? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015 Feb 15;85(3):380-1 | 2015 |
Hillegass WB, Brott BC, Optimal DAPT duration: each in their own time. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015 Jan 1;85(1):41-2 | 2015 |
Hillegass WB, Diabetes and everolimus-eluting stents: good offense scores but defense wins tough games. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013 Apr;81(5):766-7 | 2013 |
Hillegass WB, Stent paleology: diabetic lessons from extinct stents. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013 Jun 1;81(7):1125-6 | 2013 |
Hillegass WB, Brott BC, Thromboaspiration and IIb/IIIa therapy in STEMI: abciximab redux? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013 Oct 1;82(4):612-3 | 2013 |
Hillegass WB, Brott BC, Saphenous vein grafts: two substrates, two treatments? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012 Dec 1;80(7):1137 | 2012 |
Hillegass WB, Benefit of renal artery stenting: is on-target therapy the observational bias? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012 Sep 1;80(3):351 | 2012 |
Hillegass WB, Rotational atherectomy for heavily calcified unprotected left main disease: proceed with caution. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012 Aug 1;80(2):221 | 2012 |
Hillegass WB, Implicit rationing of percutaneous coronary intervention: the left main test case. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012 Jun 1;79(7):1117 | 2012 |
Hillegass WB, Diabetes and percutaneous coronary intervention drug-eluting: stents whenever feasible. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011 Nov 1;78(5):718-9 | 2011 |
Hillegass WB, Shock and age: the role of an early invasive strategy. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011 Oct 1;78(4):512-3 | 2011 |
Hillegass WB, High glycemic stenting menu. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010 Dec 1;76(7):934-5 | 2010 |
Hillegass WB, Bifurcation stenting: a commitment to always kiss. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010 Mar 1;75(4):614-5 | 2010 |
Hillegass WB, Length matters: outcomes of superficial femoral artery (SFA) endovascular interventions. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009 Dec 1;74(7):1096 | 2009 |
Hillegass WB, As goes the access, so goes the intervention? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009 Nov 15;74(6):932-3 | 2009 |
Hillegass WB, The modern axis of peri-procedural evil. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009 Jul 1;74(1):56-7 | 2009 |
Honors, Awards, and Recognition
Gold Research Excellence Award, UMMC | 2022 |
Silver Research Award, UMMC | 2021 |
Bronze Research Award, UMMC | 2020 |
Frank Hildner Elite Reviewer Award, Society of Cardiovascular Angiography and Intervention | 2017 |
Naomi Fineberg Distiguished New Researcher Award, Department of Biostatistics, University of Alabama at Birmingham | 2015 |
Fellow Society of Cardiovascular Angiography and Intervention (FSCAI), Society of Cardiovascular Angiography and Intervention | 2008 |
Fellow Society of Vascular Medicine and Biology (FSVMB), Society for Vascular Medicine | 2006 |
Fellow American College of Cardiology (FACC), American College of Cardiology | 2000 |
Henry Christain Award for Clinical Research, American Federation for Clinical Research | 1993 |
Young Trainee Investigator Award, American Federation for Clinical Research | 1993 |
Truman Scholar, Harry S. Truman Memorial Foundation | 1981 |
Townsend Prize, Yale University | 1980 |
Professional Membership and Service
Mississippi Chapter, American College of Cardiology, Member | 2019 - Present |
Mississippi-Alabama Chapter, American Statistical Association, Member | 2019 - Present |
American Statistical Association, Member | 2017 - Present |
Society of Vascular Medicine, Fellow | 2006 - Present |
Society of Cardiovascular Angiography and Intervention, Fellow | 1995 - Present |
American College of Cardiology, Fellow | 1990 - Present |
Committee Service
MEDICAL CENTER-FACULTY SENATE, Member | 2023 - Present |
SOM-Systems Based Practice, Member | 2021 - Present |
DEI Committee, Member | 2021 - Present |
Clinical Learning Environment Committee, Evidence Based Medicine/Epidemiology/Statistics, Member | 2020 - Present |
Steering Committee MCCTR, Member | 2019 - Present |
Internal Advisory Committee, Mississippi Center for Clinical and Translational Research/COBRE., Member | 2019 - Present |
Other Service
Cochrane Comparing Multiple Interventions Methods Group, Member | 2020 - Present |
Journal of Interventional Cardiology | 2020 - Present |
Kirklin Institute for Research of Surgical Outcomes (KIRSO), University of Alabama at Birmingham, Statistician/Participant | 08/2017 - 12/2018 |
National Cardiovascular Data Registry Pinnacle Registry Limited Data Set Workgroup, Chair | 2017 - 12/2017 |
National Cardiovascular Data Registry Science and Quality Oversight Committee Data Governance Subcommittee, Scientific Oversight of NCDR | 04/2016 - Present |
Interventional Cardiovascular Maintenance of Certification Exam beta tester, American Board of Internal Medicine., Test and Advise Board Certification Exam Questions | 2014 - 2018 |
Pharmacoepidemiology and Economics Research (PEER) Group, University of Alabama at Birmingham, Member/Participant | 2011 - 2017 |
Real World PCI Outcomes Registry, Steering Committee | 2009 - 12/2010 |
American College of Cardiology Foundation/Brookings Project Longitudinal PCI Registry Internal Workgroup, Member/Participant | 2009 - 2010 |
Catheterization and Cardiovascular Interventions | 2008 - Present |
Ad Hoc Peripheral Vascular Disease Committee, Society for Cardiovascular Angiography and Intervention, Member/Participant | 03/2007 - 03/2011 |
American College of Cardiology Live Programs Committee., Participant/Member | 2007 - 2010 |
Research and Publications Subcommittee, American College of Cardiology -National Cardiovascular Data Registry (ACC-NCDR) CathPCI Registry., Reviewed and Graded Research Proposals for CathPCI NCDR Registry | 03/2006 - 03/2013 |
Peripheral Vascular Disease Writing Committee, BARI 2D Trial, Participant/Member | 2006 - 2010 |
Quality of Life Writing Committee, BARI 2D Trial, Member/Participant/Researcher | 2006 - 2012 |
Training Program Standards Committee, Society for Cardiovascular Angiography and Intervention, Member/Participant | 2005 - 12/2010 |
Sound Wave Inhibition of Neointimal Growth Trial. Data and Safety Monitoring Board (DSMB)., Member | 2000 - 12/2002 |
Peripheral Atherosclerosis Research Consortium, Founding Member | 1998 - 12/2001 |
Patient outcomes in acute coronary syndrome registry. (PRO-ACS) Scientific Advisory Group, Scientific Advisory Group Member | 1998 - 12/2000 |
Lamifiban with thrombolysis in acute MI PARADIGM Trial. Data and Safety Monitoring Board (DSMB), Member of DSMB | 1995 - 12/1996 |
Epic Trial Clinical Endpoints Review Committee, Member Adjudicating Events | 1992 - 12/1993 |
Teaching Experience
Population Health, Course, Preceptor, Dissertation Research - Ward | Spring 2024 |
Population Health, Course, Preceptor, Dissertation Research - Ward | Fall 2024 |
Population Health, Course, Preceptor, Dissertation Research - McNeill | Fall 2024 |
Population Health, Course, Preceptor, Dissertation Research - Christman | Fall 2024 |
Population Health, Course, Course Director, Bayesian Statistical Methods | Fall 2024 |
Population Health, Course, Preceptor, Dissertation Research - McNeill | Spring 2024 |
Population Health, Course, Preceptor, Dissertation Research - Christman | Spring 2024 |
BDS 750, Population Health, Course, Course Director, Study Design and Clinical Trials | Spring 2023 - 2023 |
PHS 753, Population Health, Course, Course Director, Systems Science and Economics for Population Health | Spring 2023 - 2023 |
BDS 750, Population Health, Course, Course Director, Study Design and Clinical Trials | Fall 2023 |
BDS 797, Population Health, Course, Course Director, Advanced Study Design and Network Meta-Analysis Methods | Fall 2023 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Ward | Spring 2023 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Ward | Fall 2023 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Ward | Summer 2023 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Christman | Summer 2023 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Christman | Fall 2023 |
BDS 750, Population Health, Course, Course Director, Study Design and Clinical Trials | Spring 2022 - 2022 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Adnan | Spring 2022 |
BDS 792, Population Health, Course, Course Director, Biostatistical Consulting | Fall 2021 - 2021 |
BDS 750, Population Health, Course, Course Director, Study Design and Clinical Trials | Spring 2021 - 2021 |
PHS 753, Population Health, Course, Course Director, Systems Science for Population Health | Spring 2021 - 2021 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Adnan | Spring 2021 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Adnan | Summer 2021 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Adnan | Fall 2021 |
BDS 792, Population Health, Course, Course Director, Biostatistical Consulting | Fall 2020 |
BDS 750, Population Health, Course, Course Director, Study Design | Spring 2020 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Adnan | Spring 2020 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Adnan | Fall 2020 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Adnan | Summer 2020 |
BDS 750, Population Health, Course, Course Director, Study Design | Spring 2019 |
BDS 792, Population Health, Course, Course Director, Biostatistical Consulting | Fall 2019 |
BDS 798, Population Health, Course, Preceptor, Dissertation Research - Adnan | Fall 2019 |
Directed Student Learning
Dissertation Committee Member, Environmental Exposures and Health Advised: Lauren Pongetti | 2023 - Present |
Dissertation Committee Member, Genetic Risk of Dementia Advised: Hunter Sylvester | 2023 - Present |
Dissertation Committee Member, Cardiometabolic Risk in Children Advised: Quest Whalen | 2023 - Present |
Dissertation Committee Member, Obesity in Children Advised: Kisa Harris | 2023 - Present |
Research Advisor, Diagnosis and Progression of CKD Advised: Wesley Zhang | 2022 - Present |
Dissertation Committee Chair, Count Endpoints in Cluster Randomized Trials Advised: Taylor Ward | 2022 - Present |
Internship Advisor, Time to Life Insurance Cancellation Advised: Kendall Churchwell | 2022 - 2022 |
Research Advisor, Factors Associated with Suicidal Behaviors in MS Youth Advised: Brian Christman | 2021 - Present |
Dissertation Committee Member, QT Prolongation in Sickle Cell Disease Advised: Mengna Zhang | 2021 - Present |
Dissertation Committee Chair, A Classification and Design Framework for Run-in Phases in Comparative Therapeutic Efficacy (CTE) Trials with Quantitative Performance Assessment Advised: Mohiuddin Adnan | 2019 - 2022 |
Dissertation Committee Member, Complex Longitudinal and Survival Modeling Advised: Md. Roungu | 2019 - 2022 |
Preceptor, Clinical Training - 52 students | 2000 - 2018 |
Research Advisor, Clinical Research - 4 students | 1995 - 1999 |
Preceptor, Clinical Training - 15 students | 1995 - 1999 |
Fellows supervised
University of Alabama at Birmingham, Fellowship Director, 21 fellows supervised, Interventional Cardiovascular | 01/2003 - 12/2009 |
University of Alabama at Birmingham, Research Advisor, 6 fellows supervised | 11/2000 - 12/2018 |
University of Alabama at Birmingham, Attending Physician, 78 fellows supervised, Cardiovascular | 11/2000 - 12/2018 |
Vanderbilt University Medical Center, Research Advisor, 3 fellows supervised, Interventional Clinical Research | 01/1995 - 08/1999 |
Vanderbilt University Medical Center, Attending Physician, 39 fellows supervised | 01/1995 - 08/1999 |
Residency Training
University of Alabama at Birmingham (39 residents), Attending Physician | 2000 - 12/2018 |
Vanderbilt University Medical Center (20 residents), Attending Physician | 1995 - 08/1999 |