Kenneth J. Hardy
PROFESSOR EMERITUS
Department:
SOM-Medicine-RHEUM
Email:
khardy@umc.edu
Education
| University of California SChool of Medicine, San Francisco, CA, Rheumatology/Clinical Immunology | 1986 |
| University of California School of Medicine, Davis, CA | 1983 |
| Louisiana State University School of Medicine, MD, Medicine | 1980 |
| University of Texas Graduatre School of Biomedical Sciences, MD Anderston Hospital and Tumopr Institute, PhD, Biochemistry/Molecular Biology | 1977 |
| University of New Orleans, New Orleans, LA, MS, Biological Sciences/Biochemistry | 1973 |
| University of New Orleans, BS, Biological Sciences | 1968 |
Specialty Certification Licensure
| Licensure, Louisiana medical license | |
| Licensure, Mississippi State Board of Medical Licensure | |
| NPI, National Provider Identification Number | 06/2006 - Present |
| DEA, Drug Enforcement Administration | 10/2011 |
Current Positions
| Professor, School of Medicine, Department of Medicine | 2005 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Academic Appointments or Other Previous Appointments
| Professor, University of Mississippi Medical Center, Jackson, MS, School of Medicine, Department of Medicine | 11/1993 - 2005 |
| Professor, University of Mississippi Medical Center, Jackson, MS, School of Medicine, Department of Medicine | 11/1993 - 2004 |
| Associate Professor, University ofAlabama School of Medicine, School of Medicine, Department of Medicine | 09/1990 - 11/1993 |
| Attending Physician, VA Hospital, School of Medicine, Department of Medicine | 09/1990 - 11/1993 |
| Assistant Professor, Baylor College of Medicine, School of Medicine, Department of Medicine | 04/1989 - 09/1990 |
| Attending and Consulting Physician, Harris County Hospitals, School of Medicine, Department of Medicine | 07/1986 - 09/1990 |
| Attending and Consulting Physician, Houston VA Hospital, School of Medicine, Department of Medicine | 07/1986 - 09/1990 |
| Attending and Consulting Physician, Methodist Hospital, School of Medicine, Department of Medicine | 06/1986 - 09/1990 |
| Assistant Professor, Baylor College of Medicine, School of Medicine, Department of Medicine | 07/1986 - 04/1989 |
| Assistant Professor, University of California School of Medicine, School of Medicine, Department of Medicine | 1986 - 07/1986 |
Publications
Journal Article | |
| Hardy KJ, Singh A and deShazo R Immune Complex Diseases Version 2.0. Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester. Doi:10.1002/9780470015902.a0002164.pub2. | 2009 |
| Sanders S, Hardy, KJ, and McMurray RW New Diagnostic and Treatment Approaches for Spondyloarthritis Arthritis Research: Treatment and Management, pp. 27-58. Nova Science Publishers | 2005 |
| Jenkins JJ and Hardy KJ Biological Modifiers in the Treatment of Rheumatoid Arthritis Am. J. of Med. Sci., 323:197-205 | 2002 |
| McMurray RW and Hardy KJ Cox-2 Inhibitors: Today and Tomorrow Am. J. of Med. Sci., 323:181-189 | 2002 |
| Hardy KJ and deShazo R Immune Complex Disease Encyclopedia of Life Sciences 1st Edition, Vol. 9, pp. 478-485. London: Nature Publishing Group | 2002 |
| Hardy, K.J. and deShazo, R. Immune Complex Disease, Version 1.0 Encyclopedia of life Sciences. London: Nature Publishing Group, 2002, Vol 9, pp 478-485 | 2002 |
| Jenkins JJ, Hardy KJ and McMurray RW The Pathogenesis of Rheumatoid Arthritis: A Guide to Therapy Am. J. of Med. Sci. 323:171-180 | 2002 |
| McMurray RW, Ndebele K, Hardy KJ and Jenkins JK 17-β-Estradiol suppresses IL-2 and IL-2 receptor Cytokine, 14:324-333 | 2001 |
| Lorenz HM, Lagoo AS, Lagoo-Deenadayalay SA, Barber HW, Kalden JR and KJ Hardy Epitope-specific signaling through CD45 on T-lymphocytes leads to CAMP synthesis in monocytes after ICAM-1 dependent cellular interaction Eur. J. of Immunology, 28:2306-2310 | 1998 |
| Hauser CJ, Pratibha J, Xinchun Z, Kregor P, Hardy KJ, Devidas M, Scott P and Hughes JL Production of Interleukin-10 In Human Fracture Soft-tissue Hematomas Shock, 6:3-6 | 1996 |
| Lagoo AS, George JF, Naftel DC, Griffin AK, Kirklin JK, Lagoo-Deenadayalan S, Hardy KJ, Savune T, and McGiffin DC Semi-quantitative measurement of cytokine mRNA in endomyocardium and PMBC's from human heart transplant recipients J. Heart and Lung Transplantation 15: 206-217 | 1996 |
| Lagoo-Deenadayalan S, Lagoo, AS, Lemons JA, Lorenz H, McDaniel O, Hardy K. and Barber WH Donor Specific Bone Marrow Cells Suppress Lymphocyte Reactivity to Donor Antigens and Differentially Modulate TH1 and TH2 Cytokine Gene Expression in the Responder Cell Population Transplant Immunology, 3:107-127 | 1995 |
| Hauser CJ, Lagoo-Deenadayalan S Lagoo, AS, Hale E, Hardy K.J, Barber WH, Bass JD, and Poole GV Human peripheral mononuclear cells do not show pro-inflammatory patterns of cytokine transcription in early trauma Shock, 4:247-250 | 1995 |
| Hardy, KJ The Immunology of Inflammation Society Pages, J. Lab. Clin. Med, 125:293-297 | 1995 |
| Young HA and KJ Hardy The Role of Interferon- in Immune Cell Regulation J of Leucocyte Biology 58:373-381 | 1995 |
| Hauser CJ, Lagoo-Deenadayalan S, Lagoo AS, Hale E, Hardy KJ, Barber, WH, Bass, JD and Poole GV TNF-a gene expression by human peritoneal macrophages is suppressed by extra-abdominal trauma Arch. Surg., 130:1186-1191 | 1995 |
| Lorenz, H, Lagoo, AS and KJ Hardy A role for CD45 in LFA-1/ICAM-1 dependent cellular adhesion: Protein kinase C independent (CD45) versus protein kinase C-dependent (PMA) pathways to differential LFA-1 activation Blood, 83:1862-1870 | 1994 |
| Ye J, Gosh, P Cippitelli, M Subleskei J, Hardy, KJ, Ontaldo J.R and Young HA Characterization of Silencer Regulatory Element in the Human Promoter J. Biol. & Chem. 269:25728-25734 | 1994 |
| Lagoo AS, Lagoo-Deenadayalan, S Lorenz, H, Barber W H and KJ Hardy IL-2, IL-4, and IFN- gene expression and secretion in superantigen-activated T cells: distinct requirement for costimulatory signals through adhesion molecules J. Immunology, 152:1641-1652 | 1994 |
| Hardy KJ, Young HA, and AS Lagoo Molecular Diagnostics Immunology and Allergy Clinics of North America; Diagnostic Laboratory Immunology, W.B. Saunders Co., Vol. 14, No.2, 199-223 | 1994 |
| Lagoo, AS, Eldridge, JH, Lagoo-Deenadaylan, S Barber, HW Black, CA, Hardy, KJ McGhee, JR and Beagley, KW Peyer's Patch CD8 Positive Memory T Cells Secrete Th1 and Th2 Cytokines and Provide Help for Immunoglobulin Secretion. Eur. J. of Immunology, 29:3087-3092. | 1994 |
| Lagoo-Deenadayalan, S Lagoo, AS, Barber HW and KJ Hardy A standardized approach to PCR-based semi-quantitation of multiple cytokine gene transcripts from small cell samples Lymphokine and Cytokine Research, 12:59-67 | 1993 |
| Hardy KJ and RR Rich Molecular biology: An overview of its principles, applications, and contributions to allergy/immunology Allergy: Principles and Practice, 4th Edition, E. Middleton, Jr., C.E. Reed, E.F. Ellis, N. F. Adkinson, Jr., J.W. Yunginger, editors. C.V. Mosby Company, Vol. 2, pp 22-46 | 1993 |
| Lagoo-Deenadayalan,S, Lagoo, AS, Hardy K.J. and EA Grimm Tumor recognition and lytic competence of IL-2 activated lymphocytes: Regulation of both antibody-independent and dependent cellular cytotoxicity via p75 IL-2R Lymphokine and Cytokine Research, 11:207-213 | 1993 |
| Whelan, JP Shearer, WT, Gilliam, EB, and K J Hardy A PKC-activating phorbol ester accelerates the T cell antigen receptor-stimulated PI cycle in normal human CD4+ T cells J. Immunol. 148:2872-2878. | 1992 |
| Hardy J and M Everson Cytokines: Mediators of the immune system. UAB Insight Spring Edition, UAB Press, p. 5 | 1992 |
| Hardy, K.J. and H.A. Young IFN- gene structure and regulation. Interferon: Principles and Medical Applications, S. Baron, et al, editors, 47-76 | 1992 |
| Hardy KJ and R Rich Molecular biology and the study of allergy and immunology Allergy: Principles and Practice, 3rd Edition, Update Series. Vol. 8, 1-17. E. Middleton, Jr., C.E. Reed, E.F. Ellis, N.F. Adkinson, Jr., J.W. Yunginger, editors. Merrell Dow, U.S.A. | 1991 |
| Chrivia, JC T Wedrychowicz HA Young and KJ Hardy A model of human cytokine regulation based on transfection of gamma interferon gene fragments directly into isolated peripheral blood T lymphocytes J. Exp. Med. 172:661-664 | 1990 |
| Ciccarone VC, JC Chrivia, KJ Hardy and HA Young Identification of enhancer-like elements in the human interferon- genomic DNA. J. Immunol. 144:725-730 | 1990 |
| Young, HA and KJ Hardy Interferon-: Producer cells, activation, stimuli, and molecular genetic regulation Pharmac. Ther. 45:137-151 | 1990 |
| Young, HA, M Beckwith, AN Scott, KJ Hardy, and VC Ciccarone Role of genomic DNA sequences in the control of interferon gamma gene expression. In The Biology of the Interferon System 1988, Y. Kawade and S. Kobayashi, eds., Kodansha Scientific Ltd., Tokyo, p. 19-24. | 1989 |
| Hardy, KJ and T Sawada The product of the human gamma interferon gene superinduces its own gene expression in human peripheral blood lymphocytes J. Exp. Med. 170:1021-1026 | 1989 |
| Hardy KJ, JC Chrivia, JS Smith, SS Rich, HA Young and T Sawada Positive and negative effectors of gamma interferon gene regulation The Biology of the Interferon System, Y. Kawade and S. Kobayashi, eds., Kodansha Scientific Ltd., Tokyo, p. 33-38 | 1988 |
| Peterlin B.M, KJ Hardy and A Larsen Chromatin structure of the human HLA DR a gene in different functional states of MHC class II gene expression Mol. Cell Biol. 7:1967-1972 | 1987 |
| Hardy K B, Manger M Newton and J Stobo Molecular events involved in regulating human interferon gene expression during T cell activation J Immunol 138:2353-2358 | 1987 |
| Hellman, D, KJ Hardy, SM Lindenfeld and E.J. Ring Takayasu's arteritis associated with crescentic glomerulonephritis Arth. Rheum, Vol 30:451-454. | 1987 |
| Manger, B, A Weiss, K Hardy and J Stobo A transferrin receptor antibody represents one signal for the induction of IL 2 production by a human T cell line J. Immunol. 136:532-537 | 1986 |
| Manger, B., K. Hardy, A. Weiss, and J.D. Stobo Cyclosporin A does not block the phorbol ester/protein kinase C regulated pathway of T cell activation Fed. Proc. 45:505 | 1986 |
| Manger B, K Hardy A, Weiss and J Stobo. Differential effect of Cyclosporin A on activation signaling in human T cell lines J. Clin. Invest. 77:1501-1506. | 1986 |
| WeissA, J. Imboden, K Hardy, B Manger C Terhorst and J Stobo The role of the T3/antigen receptor complex in T cell activation In Annual Review of Immunology, Vol. 4, p. 593-619 | 1986 |
| Hardy, KJ, BM Peterlin, RE Atchison and JD Stobo Regulation of expression of the human interferon gene Proc. Natl. Acad. Sci. USA 82:8173-8177 | 1985 |
| Beary, DA, DL Vizard, RA LaBaiche, KJ Hardy and SE Bryan Preliminary characterization of chelation sensitive nucleoprotein particles Biochem. Biophys. Res. Comm. 104:491-497 | 1982 |
| Kilianska Z, KJ Hardy, JD Chiu and LS Hnilica Inhibition of DNA transcription by chromosomal non histone proteins. Internatl. J. Biochem.3:1127-1132 | 1981 |
| Bryan, SE, DL Vizard, D.A. Beary, RA LaBaiche and K J Hardy Partitioning of zinc and cooper within subnuclear nucleoprotein particles Acids Res. 9:5811-5823 | 1981 |
| Hardy K and M Alspaugh The induction of antinuclear antibodies with specificity for nuclear antigens of transformed human lymphocytes Cell Different. 10:93-99 | 1981 |
| Hnilica, L, J Chiu, K Hardy, H Fujitani, and R Briggs Antibodies to nuclear chromatin fractions In The Cell Nucleus, E. Harris Busch, ed. Academic Press, 2nd Ed., Ch. 9, p. 307-331. | 1978 |
| Hnilica, LS, JF Chiu, H Fugitani, KJ Hardy, and RC Briggs Antigenic properties of non histone proteins in chromatin. In Differentiation and Development, W.J. Whilan and J. Schultz, eds. Academic Press, p. 237-245 | 1978 |
| Hnilica, L S, J F Chiu, K J Hardy, and H Fujitani Chromosomal proteins in differentiation. In Cell Differentiation and Neoplasia Grady F. Saunders, ed. Academic Press, p. 325-346 | 1978 |
| Hardy KJ, JF Chiu, K Sakuma and L S Hnilica Distribution of globin specific DNA sequences in fractionated chromatin Int. J. Biochem. 9:357-363 | 1978 |
| Hardy, KJ, JF Chiu, AL Beyer and LS Hnilica Immunological properties of fractionated avian erythroid nuclei J. Biol. Chem. 253:5825-5831 | 1978 |
| Hardy, KJ, H Fujitani, JF Chiu, and LS Hnilica Functional organization of chromatin. In Receptors and Hormone Action, Burt O'Malley, ed. Academic Press, Vol. I, p. 151-194. | 1977 |
| Bryan, SE, SS Simons, DL Vizard, and KJ Hardy Interactions of mercury and copper with constitutive heterochromatin and euchromatin in vivo and in vitro. Biochemistry 15:1667-1676 | 1976 |
| Hardy, KJ, and S E Bryan In vivo and in vitro uptake of mercury and copper into discrete regions of mouse liver nuclei. In The Biological Implications of Metals in the Environment ERDA Symp. Ser. 42:488-506 | 1975 |
| Hardy, KJ, and SE Bryan Localization of uptake of copper into chromatin Toxicol. and Appl. Pharmacol. 33:62-6. | 1975 |
| Sakuma, K and K Hardy The Florida colloquium on molecular biology Prot. Nucl. Acids Enzym. 20:1240-1242 | 1975 |
| Bryan, S, S Simons, C Lambert, and K Hardy Intranuclear uptake of mercury in vivo. Science 186:832-834 | 1974 |
| Bryan, SE, AL Guy and KJ Hardy Metal constituents of chromatin. Interactions of mercury in vivo Biochemistry 13:313-319 | 1974 |
| Sweet, BH, JS McHale, KJ Hardy, and E Klein Concentration of virus from water by electro endosmosis and forced flow electrophoresis Prep. Biochem. 1:77-89. | 1971 |
| Sweet B, J McHale, K Hardy, F Morton, F Smith, and E Klein Concentration of virus from water by osmotic ultrafiltration I. Biological aspects. Water Res. 5:823-825. | 1971 |
| Hardy, KJ Methods of Molecular Medicine. Molecular Biology Course Syllabus: Proc. 45th Ann. Meet., Am. Acad. All. Immunol., Milwaukee, AAAI, p. 13-8. | 1989 |
Abstracts | |
| CJ Hauser, S Lagoo, A Lagoo, . Hale, KJ Hardy WH Barber JD Bass and GV Poole Constitutive priming of Tumor Necrosis, Factor-a, but not IL-1b transcription in normal human peritoneal macrophages J. Miss. Acad. Sci. 50:61 | 1995 |
| CJ Hauser, S Lagoo, A Lagoo E Hale, KJ Hardy WH Barber and GV Poole Priming of Human Peritoneal macrophages is suppressed by extra-abdominal trauma Surgical Infection Society 63 | 1995 |
| GV Poole CJ Hauser, S Lagoo, KJ Hardy and A Lagoo Trauma upregulates human periheral monoculear cell expression of IL-10, not pro-inflammatory cytokines Shock 3(suppl):18 | 1995 |
| Hardy KJ and A Lagoo Exploring a completely new approach to the therapy of autoimmunity Clinical Research 39:457A | 1991 |
| Smith JG, KJ Hardy and SS Rich Role of TGF in suppressor T cell factor regulation of lymphokine gene expression. J. Cell. Biochem., Suppl. 13a, 315. | 1989 |
| Hardy, KJ and HA Young Positive and negative genetic regulatory elements mediate transcriptional regulation of human gamma IFN gene expression Arthritis Rheum. 31:S84 | 1988 |
| Hardy, K.J. and H.A. Young. Interdomain communication between intronic and 5 flanking regions of the human IFN gamma gene during T cell activation J. Interf. Res. 7:697 | 1987 |
| Hardy, KJ, B Manger, BM Peterlin and J.D. Stobo T cell activation and mechanisms of regulating human lymphokine gene expression Clin. Res. 34:495A | 1986 |
| Peterlin, BM and KJ Hardy Changes in chromatin structure with HLA Dr alpha gene activation Fed. Proc. 44:783 | 1985 |
| Hardy K, R Atchison, M Peterlin and J Stobo Regulation of human gamma interferon gene expression: DNase I mapping Fed. Proc. 44:1310 | 1985 |
Editorial Commentary | |
| Bianchi, N, J Ayres, K Hardy, and M Mouton Karyological characterization of primary cells from New Zealand rabbits Mammalian Chromosome Newsletter 13:69-70 | 1972 |
| Bianchi, NO, BH Sweet, KJ Hardy, and M Mouton Repetitive heterochromatin and chromosomal transformation in continuous cell lines from New Zealand rabbits Mammalian Chromosome Newsletter 13:60-61 | 1972 |
| Bianchi, NO, BH Sweet, KJ Hardy, and D Unthank Repetitive heterochromatin distribution in the chromosome complement of normal and transformed cells from the African green monkey Mammalian Chromosome Newsletter 13:59-60 | 1972 |
| KJ Hardy, JS McHale, HE Hopps, BC Meyer, JT McHale, N.O. Bianchi, and BH Sweet. Chromosome analysis of four continuous cultures of rabbit somatic cells Mammalian Chromosome Newsletter 12:16-17 | 1971 |
Presentations
| Invited Symposia, Evaluation of Metabolic Bone disease and Low Bone Mass in a VA Hospital Renal Dialysis Population, Amgen Rheumatology Fellowship Symposium | 2004 |
| National and International Invited Seminars/Lectures, Efficacy of Melatonin versus Bromcriptine in the Treatment of Primary Fibromyalgia Syndrome (PFS) in a Double Blind, Placebo Controlled Trial., American College of Rheumatology, International Meeting, San Diego, CA | 1998 |
| National and International Invited Seminars/Lectures, Variations in Frequency Distribution of DR Genotypes in African Americans, 21st. Annual Meeting, American Society for Histocompatibility and Immunogenetics, Dallas, Texas | 09/1995 |
| National and International Invited Seminars/Lectures, Accessory Pathways of T Cell Activation: Interactions with Human and Porcine Endothelial Cells, FASEB, San Francisco, Ca | 1995 |
| National and International Invited Seminars/Lectures, Early Suppression of Cytokine Transcription by Human Peritoneal Macrophages in Extra-Abdominal Trauma, 56th Annual Meeting of the Society of University Surgeons, Denver, Co | 1995 |
| National and International Invited Seminars/Lectures, Rheumatoid Arthritis Synovial Fibroblasts Support Distinct Patterns of Cytokine Gene Induction in Naive and Memory T Cells, FASEB, San Francisco, Ca | 1995 |
| National and International Invited Seminars/Lectures, Accessory Pathways of T Cell Activation in Xenotransplantation., 20th Annual Meeting of the American Society for Histocompatibility and Immunogenetics, Pittsburgh, Penn | 10/1994 |
| National and International Invited Seminars/Lectures, Donor-specific bone marrow cells modulate cytokine expression levels in MLR: Possible mechanisms of enhancement of graft survival., FASEB, Anaheim, Ca | 10/1994 |
| National and International Invited Seminars/Lectures, Accessory cells differentially modulate Levels of cytokine gene expression in superantigen-activated human naive T cells, FASEB, Anaheim, Ca | 1994 |
| National and International Invited Seminars/Lectures, Cytokine gene expression in superantigen-activated naive and memory T cells from adult human peripheral blood., American Association of Immunologist/Clinical Immunology Society Meeting, Denver, Co | 05/1993 |
| National and International Invited Seminars/Lectures, Cytokine gene transcripts in peripheral blood mononuclear cells of renal transplant patients: Effect of post-transplantation donor specific bone marrow infusion, Nineteenth Annual Meeting of the American Society of Transplant Surgeons, Houston, TX | 05/1993 |
| National and International Invited Seminars/Lectures, Endothelial cells provide accessory signals for cytokine gene expression by superantigen - and anti-CD2 Activated T cells, American Association of Immunology/Clinical Immunology Society Meeting, Denver, Co | 05/1993 |
| National and International Invited Seminars/Lectures, On the mode of action of CD45: Signals through different CD45 epitopes induce different intracellular signals, American Association of Immunology/Clinical Immunology Society Meeting, Denver, Co | 05/1993 |
| National and International Invited Seminars/Lectures, Asensitive, non radioactive assay for measuring the expression of cytokine mRNA transcripts in cardiac transplant patients., Thirteenth Annual Meeting of the International Society for Heart and Lung Transplantation, Boca Raton, Fla | 04/1993 |
| Invited Symposia, Proinflammatory cytokine production by rheumatoid arthritis synovial fibroblasts, Keystone Symposia on Molecular and Cellular Biology: Cytokines and Cytokine Receptors: From Cloning to the Clinic, Keystone, Co | 1993 |
| Invited Symposia, The role of CD45 in modulating human peripheral blood mononuclear cell adhesion and T-lymphocyte responsiveness., . Keystone Symposia on Molecular and Cellular Biology: Cytokines and Cytokine Receptors: From Cloning to the Clinic, Keystone, Co | 1993 |
| National and International Invited Seminars/Lectures, Adhesion and signal transduction through LFA-1 and LFA-3 adhesion molecules is required for super-antigen-induced T-cell proliferation, 8th World Congress on Immunology, Budapest, Hungary | 08/1992 |
| Invited Symposia, Adhesion and signal transduction through LFA-1 and LFA-3 adhesion molecules is required for super-antigen-induced T-cell proliferation, UAB Department of Medicine 8th Annual Trainee Research Symposium, Birmingham, AL | 1992 |
| Invited Symposia, CD45 MAB induces adhesion in human PBMC through a PKC-independent pathway, UAB Department of Medicine 8th Annual Trainee Research Symposium, Birmingham, AL | 1992 |
| National and International Invited Seminars/Lectures, CD45 MAB induces adhesion in human PBMCs through a PKC-independent pathway, 8th World Congress on Immunology, Budapest, Hungary | 1992 |
| Invited Symposia, PCR-based semiquantitative analysis of multiple cytokine mRNAs, UAB Department of Medicine 8th Annual Trainee Research Symposium, Birmingham, AL | 1992 |
| National and International Invited Seminars/Lectures, Exploring a completely new approach to the therapy of autoimmunity, Fellows 40th Anniversary Conference, Snowbird Resort, Utah | 06/1991 |
| National and International Invited Seminars/Lectures, Role of DNA binding proteins in the regulation of human IFN- gene expression, International Society for Interferon Research, Nice, Italy | 1991 |
| National and International Invited Seminars/Lectures, Human cytokine regulation: New hypotheses derived from the study of regulatory elements in the human gamma interferon gene, Washington, DC, Annual meeting of the American Federation for Clinical Research | 05/1990 |
| National and International Invited Seminars/Lectures, Signal transduction in normal human T cells is poorly recapitulated by tumor cell models., Annual meeting of the American Federation for Clinical Research, Washinton,DC | 05/1990 |
| National and International Invited Seminars/Lectures, Cytokine gene regulation: A new hypothesis derived from the study of negative regulatory elements in the human gamma interferon gene, Midwinter Conference of Immunologists, Monterey, CA | 01/1990 |
| National and International Invited Seminars/Lectures, Regulation of human gamma interferon gene expression: The cytokine network, Arthritis Foundation Fellows Conference, Amelia Island Plantation, FL | 01/1990 |
| National and International Invited Seminars/Lectures, Regulation of human gamma interferon gene expression: The cytokine network, Arthritis Foundation Fellows Conference, Florence, Italy | 12/1989 |
| National and International Invited Seminars/Lectures, Positive and negative regulating elements in the human gamma interferon gene defined by transfection directly into peripheral blood T lymphocytes, 1989 Annual Meeting of the International Society for Interferon Research, Florence, Italy | 10/1989 |
| National and International Invited Seminars/Lectures, Functional elements regulating human interferon-gamma gene expression, Annual Meeting of the International Society for Interferon Research, Florence, Italy | 09/1989 |
| National and International Invited Seminars/Lectures, Tissue specific regulation of human interferon-gamma gene expression involves multiple DNA elements, Eighth Cold Spring Harbor Laboratory Conference on Cancer Cells, Cold Spring Harbor, NY | 09/1989 |
| National and International Invited Seminars/Lectures, PHA or OKT3 stimulation of CD4+ T cells sensitizes membrane phosphoinositide metabolism to modulation by phorbol ester, 7th International Congress of Immunology, Berlin, W. Germany | 07/1989 |
| National and International Invited Seminars/Lectures, Analysis of enhancer-like elements in human interferon- genomic DNA, FASEB Summer Research Conferences on Cellular and Molecular Genetics, Saxtons River, VT ( | 06/1989 |
| National and International Invited Seminars/Lectures, Cytokine update: function, networking, and molecular regulation, Winter Rheumatology Symposium, Snowmass, CO | 1989 |
| Scientific Presentations, Expression of human interferon genomic DNA in transgenic mice and analysis of enhancer like elements, FASEB Meeting, New Orleans, LA | 1989 |
| National and International Invited Seminars/Lectures, Human gamma interferon gene structure, function, and molecular regulation, FASEB Meeting, New Orleans, LA | 1989 |
| Scientific Presentations, Lectin and phorbol ester interactively modulate synthesis of selected phospholipids in human CD4+ T lymphocytes in a manner correlating with cell activation., FASEB Meeting, New Orleans, LA | 1989 |
| National and International Invited Seminars/Lectures, Methods in molecular medicine, 45th Annual Meeting of the American Academy of Allergy and Immunology, San Antonio, TX | 1989 |
| National and International Invited Seminars/Lectures, Positive and negative effectors of gamma interferon gene regulation, Annual Meeting of the International Society for Interferon Research: ISIR-JSIR Meeting on Interferon and Cytokines, p. 50. | 1989 |
| National and International Invited Seminars/Lectures, Role of genomic DNA sequences in the control of interferon gamma gene expression., Annual Meeting of the International Society for Interferon Research: ISIR-JSIR Meeting on Interferon and Cytokines, p. 4. | 1989 |
| Invited Symposia, Role of TGF in suppressor T cell factor regulation of lymphokine gene expression., UCLA Symposia, Keystone, CO | 1989 |
| National and International Invited Seminars/Lectures, Activation of stimulated human CD4+ cells correlates with phorbol ester induced modulation of selected phospholipid metabolism, 6th Annual Texas Immunology Conference, Galveston, TX | 1988 |
| National and International Invited Seminars/Lectures, Chromatin restriction release: A novel approach to the isolation and characterization of intact eukaryotic genes from isolated nuclei, 6th Annual Texas Immunology Conference, Galveston. TX | 1988 |
| National and International Invited Seminars/Lectures, Solubilization of native endogenous human gamma interferon genes directly from peripheral blood lymphocyte nuclei: Chromatin restriction release (CRR)., Annual Meeting of the International Society for Interferon Research: ISIR-JSIR Meeting on Interferon and Cytokines, p. 49., Abst. 1-23 | 1988 |
| Scientific Presentations, Chromatin structure and regulation of human gamma interferon gene expression/The Role of Chromosomal Proteins in Gene Structure and Function, L.S. Hnilica Memorial Symposium/Vanderbilt Medical Science, Nashville, TN | 1987 |
| State/Local Invited Seminars/Lectures, Molecular approaches to the diagnosis of immunologic Diseases, American College of Physicians Postgraduate Course Syllabus | 1987 |
| National and International Invited Seminars/Lectures, Molecular strategy and preliminary results at cloning a trans activator of human class II MHC gene expression, 5th Annual Texas Immunology Meeting Abstract M9, Austin, TX | 1987 |
| National and International Invited Seminars/Lectures, A monoclonal antibody directed against the transferrin receptor on a human T cell line provides one stimulus for its activation, 25th Midwinter Conference of Immunologist, Pacific Grove, CA | 1986 |
| National and International Invited Seminars/Lectures, Recombinant DNA technology and modern immunology, Plenary Session Speaker, California Association of Medical Technology Symposium | 1986 |
| National and International Invited Seminars/Lectures, T cell activation and transcriptional regulation of the human gamma interferon gene, ARA/AHPA Science Abstract, S102. | 1986 |
| National and International Invited Seminars/Lectures, T cell activation, chromatic structure, and transcriptional regulation at the human IFN- gene foci, 4th Annual Texas Immunology Meeting, Lake Texoma, TX | 1986 |
| National and International Invited Seminars/Lectures, Partitioning of zinc within subnuclear fractions, American Association for the Advancement of Science, San Francisco, CA | 1980 |
| National and International Invited Seminars/Lectures, Immunoanatomy of eucaryotic nuclear differentiation, Midwest Student Research Forum, Omaha, NE | 1978 |
| National and International Invited Seminars/Lectures, Immunoanatomy of eucaryotic nuclear differentiation, National Medical Student Research Forum, Galveston, TX | 1978 |
| National and International Invited Seminars/Lectures, Immunologically specific and transcriptionally active fraction of reticulocyte chromatin, Biophysiology Society, New Orleans, LA | 1977 |
| National and International Invited Seminars/Lectures, Non histone repressors in rat liver nuclei, Cell Biologists Meeting, Boston, MA. | 1977 |
| National and International Invited Seminars/Lectures, Globin specific transcripts of avian reticulocyte nuclei, American Society of Biological Chemists, San Francisco, CA | 1976 |
| National and International Invited Seminars/Lectures, Immunospecificity of avian reticulocyte chromatin, Federation Meeting, Atlantic City, NJ | 1976 |
| National and International Invited Seminars/Lectures, In vivo and in vitro uptake of mercury and copper into discrete regions of mouse liver nuclei, 15th Annual Hanford Life Science Symposium, Richland, WA | 1975 |
| National and International Invited Seminars/Lectures, An in vivo study of copper accumulation by liver nuclei, 9th International Congress of Biochemistry, Stockholm, Sweden | 1973 |
| National and International Invited Seminars/Lectures, An in vivo study of copper accumulation by liver nuclei, American Chemical Society Meeting, Baton Rouge, LA | 1972 |
| National and International Invited Seminars/Lectures, Chromosome analysis of four continuous cultures of rabbit somatic cells, Somatic Cellular Genetics Conference, Galveston, TX | 1970 |
| National and International Invited Seminars/Lectures, Concentration of virus from water by forced flow electrophoresis and electroendosmosis, 70th Annual Meeting of the American Society of Microbiologists, Boston, MA | 1970 |
| National and International Invited Seminars/Lectures, Sex differences in phospholipid content of serum, liver and brown fat following cold induced mobilization, 61st Annual Meeting of the American Oil Chemists Society, New Orleans, LA | 1970 |
| National and International Invited Seminars/Lectures, Spontaneous transformation in two rabbit cell cultures, Fall Meeting of the American Society of Microbiology, Tulane University, New Orleans, LA | 1970 |
| National and International Invited Seminars/Lectures, Use of electro osmosis and forced flow electrophoresis to concentrate virus from water, Meeting of the South Central Branch American Society of Microbiologists, Tulane University, New Orleans, LA | 1969 |
Honors, Awards, and Recognition
| Best Doctors in America, 11th Edition, Aiken, N. C.. | 2008 |
| Top Physicians in Americian, Consumers' Research Council of America | 2008 |
| Best Doctors in America, 10th Edition, Aiken, N. C. | 2007 |
| Best Doctors in America, 7th Edition, Aiken, N.C. | 2005 |
| Best Doctors in Americia, 6th Edition, Aiken, N.C. | 2004 |
| Best Doctors in America, 5th Edition , Aiken, N.C. | 2002 |
| Best Doctors in America, 4th Edition, Aiken, N.C. | 2001 |
| Board of Directions, MS Arthrisit Foundation | 1994 |
| Who's Who, Who's Who in the South and Southwest | 1994 |
| Merit Review Award Recipient, Veterans Administration | 1992 |
| J.V. Satterfield Arthritis Investigator Award, National Arthritis Foundation | 1988 |
| Scientific Excellence Award, International Interferon Research Society | 1988 |
| Recipient/ Investigator Award, Arthritis Foundation | 1987 |
| Scientific Excellence Award, International Interferon Research Society | 1987 |
| Scholor Award/ARA Senior Rheumatology Award, Merck, Sharp & Dohme | 1986 |
| Finalist, National Midwest Medical Student Research Forum | 1977 |
| Fellowship Award, Greater New Orleans Cancer Association | 1972 |
| Beta Beta Beta/Biological Honor Society, University of New Orleans | 1971 |
Professional Membership and Service
| Abbott, Amgen, Merck, Wyeth and Endo Pharmceutical Companies, Guest Speaker, Speaker's Bureau | 2005 - Present |
| Professional Consulting Services, Chairperson | 2004 - Present |
| Professional Consulting Servies, CEO | 2004 - Present |
| Searle, Pfizer, Amgen and merck Pharmaceutical Companies, Speaker's Bureau | 2004 - Present |
| Molecular Division of the "UAB Cytokine Core Facility, Director, University of Alabama School of Medicine at Birmingham | 1991 - 1993 |
| Rheumatology at HealthSouth Hospital, Originator and Research Director, University of Alabama Birmingham | 1991 - 1993 |
| STAR "Salellite Treatment of Arthritis and Rheumatism'" Program, Originator and Director, University of Alabama Birmingham | 1991 - 1993 |
| Multipurpose Arthritis Center, Scientist, University of Alabama School of Medicine at Birmingham | 1990 - 1993 |
| Hoefer Scientific instruments, Inc., Consultant | 1983 - 1990 |
| Department of Biological Sciences, Research Consultant, University of New orleans | 1976 - 1980 |
| Department of Biochemistry, Cancer Center, Predoctoral Research Associate, Vanderbilt University School of Medicine | 1973 - 1976 |
| American Association of Immunologists, Member | |
| American College of Rheumatology, Member | |
| American Colllege of Physicians, Member | |
| Association of Subspecialty Professors, Member | |
| International Society of Clinical Densitometry, Member | |
| Mississippi Arthritis and Rheumatism Society, Member |
Committee Service
| Senior Faculty Mentoring Committee, Chair | 2011 - Present |
| Faculty Mentoring Committee- Jason Taylor, MD, Chair | 2011 - Present |
| Faculy Mentoring Committe- Susanne Sanders, M.D., Chair | 2011 - Present |
| Rheumatology Fellows Review Committee, Member | 1998 - Present |
Community Service
| Professional Photography and Choriography, Volunteer Assistant with Ballet Mississippi | 2008 - Present |
Teaching Experience
| Medicine, Lecture, Lecturer, Rheumatology Sign Ins | Winter |
| 631, Medicine, Lecture, Lecturer, Internal Medicine Clerkship | Fall 2011 |
| Medicine, Lecture, Lab Presenter, Rheumatology SignIns | Spring 2011 |
| Medicine, Lecture, Lecturer, Rheumatology SignIns | Winter 2011 |
| Medicine, Lecture, Lecturer, Rheumatology Signins | Fall 2010 |
| Medicine, Lecture, Lecturer, Rheumatology Signin | Summer 2010 |
| Medicine, Lecture, Lecturer, Rheumatology Signins | Summer 2010 |
Residency Training
| Rheumatology Fellowship Training Program, Program Director | 2004 - 2004 |