Eric M. George

Eric M. George

Associate Professor

Department:
SOM-Physiology & Biophysics

Email:
egeorge@umc.edu

Work Phone:
(601) 984-5299

Education

University of Mississippi Medical Center, PhD, Biochemistry2010
University of Mississippi Medical Center, MS, Biological Sciences2009
University of Mississippi, BA, Biochemistry/History2002

Current Positions

Assistant Professor, School of Medicine, Department of Biochemistry08/2013 - Present
Assistant Professor, School of Medicine, Department of Physiology And Biophysics03/2013 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Instructor, University of Mississippi Medical Center, School of Medicine, Department of Physiology And Biophysics07/2011 - 07/2011

Sponsored Program Funding

Extramural, A novel Therapy for Preeclampsia, NIH/NLBI07/2017 - 06/2022
Extramural, A novel proangiogenic therapy for preeclampsia, AHA07/2016 - 06/2018
Extramural, A novel proangiogenic therapy for preeclampsia, NIGMS03/2014 - 03/2016
Extramural, Hypertensive Mechanisms in Preeclampsia, NHLBI03/2014 - 02/2017
Extramural, A Novel Protein Delivery System for Therapy of Preeclampsia, NHLBI01/2014 - 12/2018
Intramural, Development of an anti-angiogenic sFlt-1 miniprotein for treatment of corneal neovascularization, IRSP05/2013 - 04/2014
Extramural, The Kidney and Pregnancy, American Heart Association07/2011 - 06/2013

Publications

Journal Article

George EM The disease of theories: unravelling the mechanisms of preeclampsia The Biochemist. 39:1: 22-25.2017

Review Article

Palei AC, Spradley FT, Warrington JP, George EM, and Granger JP Pathophysiology of Hypertension in Preeclampsia: A Lesson in Integrative Physiology Acta Physiol (Oxf). 2013 Apr 16. Epub ahead of print2013

Abstracts

Colson AS, DixonJ, George EM, and Granger JP Heme oxygenase-1 attenuates hypoxia-induced superoxide production in placental villi FASEB J March 17, 2011 25:836.92011
George EM, Cockrell K, Arany M, Stec DE, and Granger JP Heme oxygenase-1 induction attenuates sFlt-1 induced hypertension in pregnant rats FASEB J March 17, 2011 25:836.72011
George EM, Adair TH, and Granger JP Regulation of sFlt-1 secretion by adenosine receptor signaling in rat placental villous explants FASEB J, Apr 2010: 24: 1041.112010

Book Chapter

George EM and Granger JP Animal models for investigating pathophysiological mechanisms of preeclampsia In Lindheimer MD, Roberts JM, and Cunningham FG (Eds.), Chesley’s Hypertensive Disorders of Pregnancy, 4th Edition. Elsevier.2015
Granger JP and George EM Role of the Kidneys in Hypertension In Schrier RW, Coffman TM, Falk RJ, Molitoris BA, and Neilson EG. (Eds.), Schrier’s Diseases of the Kidney, 9th ed. Lippincott Williams & Wilkins.2012
George EM and Granger JP Vascular Mechanisms of Hypertension in the Pathophysiology of Preeclampsia In Hill, J.A., Griendling, K., and Olson, E.N. (Eds.), Muscle: Fundamental Biology and Mechanisms and Disease. Elsevier.2012

Presentations

National and International Invited Seminars/Lectures, Shedding of the Placental Glycocalyx in Response to Ischemia and Hypoxia., International Society for Hypertension in Pregnancy 2018, Amsterdam, The Netherlands10/2018
State/Local Invited Seminars/Lectures, Preeclampsia: Unanswered Questions and New Opportunities, UMMC Department of Physiology, Jackson, MS07/2018
National and International Invited Seminars/Lectures, Animal Models for Preeclampsia, Predicting, Preventing and Treating Preeclampsia Workshop. NIH., Bethesda Maryland03/2018
State/Local Invited Seminars/Lectures, Preeclampsia: Challenges and Opportunities, UMMC Department of Physiology, Jackson, MS06/2017
State/Local Invited Seminars/Lectures, The Placental Glycocalyx in Pregnancy and Preeclampsia, UMMC Department of Physiology, Jackson, MS05/2016
National and International Invited Seminars/Lectures, Extracellular Matrix Remodeling in the Etiology of Preeclampsia., Experimental Biology 2016, Boston, MA04/2016
State/Local Invited Seminars/Lectures, Novel anti-angiogenic therapies for ocular disorders, UMMC CRRC, Jackson, MS05/2015
State/Local Invited Seminars/Lectures, New Molecular Mechanisms in the Pathogenesis of Preeclampsia., UMMC Department of Pharmacology, Jackson, MS11/2014
National and International Invited Seminars/Lectures, Preeclampsia and Cardiovascular Disease., International Society for Hypertension 2014, Athens, Greece06/2014
State/Local Invited Seminars/Lectures, New Pathogenic Mechanisms in Preeclampsia, Department of Biochemistry, Jackson, MS10/2013
National and International Invited Seminars/Lectures, Transcriptomics of placental ischemia/new peptide therapies for preeclampsia, Tox Talx 2013, Mill Valley, CA06/2013
National and International Invited Seminars/Lectures, Hypoxia-induced Heparanase Regulates sFlt-1 Release from Placental Chorionic Villi, American Heart Association’s Council on High Blood Pressure Research 2012 Scientific Sessions, Washington, DC09/2012
National and International Invited Seminars/Lectures, Is HO-1 a potential therapeutic of pre-eclampsia, 7th International Congress on Heme Oxygenases and Related Enzymes, Edinburgh, Scotland05/2012
National and International Invited Seminars/Lectures, Heme Oxygenase-1 as a Potential Therapeutic Target for the Treatment of Preeclampsia, • APS Physiology of Cardiovascular Disease: Gender Disparities, Jackson MS10/2011
Invited Symposia, Heme Oxygenase-1 Negatively Regulates sFlt-1 Production in Placental Villi by its Metabolic Byproducts Carbon Monoxide and Bilirubin, American Heart Association, Council on High Blood Pressure Research, Orlando, FL09/2011
Invited Symposia, Heme oxygenase-1 induction attenuates sFlt-1 induced hypertension in pregnant rats, FASEB, Washington, DC04/2011
State/Local Invited Seminars/Lectures, New insights into the function of linker histones, • Engineer Research and Development Center, US Army Corps of Engineers, Visksburg, MS02/2011

Honors, Awards, and Recognition

University of Mississippi Medical Center Excellence in Research Award-Gold Medal, UMMC2018
APS Early Career Advocacy Fellowship, American Physiological Society2016
APS WEH New Investigator Award, American Physiological Society2015
University of Mississippi Medical Center Excellence in Research Award-Silver Medal, UMMMC2015
University of Mississippi Medical Center Excellence in Research Award – Bronze Medal, UMMC2014
HBPR Trainee Advocacy New Investigator Travel Award, American Heart Association2011
American Heart Association Hypertension Summer School Travel Award, American Heart Association2010

Professional Membership and Service

Society for Reproductive Investigation, Member2018 - Present
American Heart Association, Member2010 - Present
American Physiological Society, Member2009 - Present

Committee Service

AHA High Blood Pressure Council Leadership Committee Advocacy Representative, Steering Comittee Member2018 - Present
AHA Vascular Biology and Blood Pressure Fellowship Study Section, Member2018 - Present
University of Mississippi Medical Center Postdoctoral Advisory Committee, Member2015 - 2016
Trainee Advocacy Committee, APS Sex and Gender Research Interest Group, Steering Comittee Member2015 - Present
University of Mississippi Medical Center School of Graduate Studies in the Health Sciences Alumni Board of Directors, Member2013 - 2016
AHA Summer Undergraduate Fellowship Study Section, Member2012 - Present
Research Trainee Advisory Subcommittee for the AHA’s Council on High Blood Pressure, Member2010 - 2017

Other Service

AHA Vascular Biology and Blood Pressure Fellowship Study Section07/2018 - Present
Physiological Genomics05/2017 - Present
MSU Veterinary School Intramural Research Grant Review Panel07/2016 - 06/2017
Hypertension07/2015 - Present
Medical Research Council, United Kingdom2015 - Present
French National Research Agency2015 - Present
Italian National Research Agency2015 - Present
Obstetric and Pediatric Pharmacology2015 - Present
Intramural Research Support Program (IRSP) Reviewer2013 - Present
AHA Summer Undergraduate Research Fellowship Study Section07/2011 - Present
Reproduction, Fertility and Development
Redox Report
Frontiers in Pharmacology
Clinical Biochemistry
Journal of Molecular Histology
Experimental Physiology
PLOS ONE
Reproductive Sciences
Journal of Cardiovascular Pharmacology
Clinical and Experimental Hypertension
BioMed Research International
Current Molecular Medicine
Gynecology and Obstetrics: Current Research
Placenta
Biochemistry and Cell Biology
International Journal of Hypertension
European Journal of Obstetrics & Gynecology and Reproductive Biology
Clinical Sciences
American Journal of Hypertension
International Journal of Biological Sciences

Teaching Experience

PHYSIO611, Graduate, Course, Lecturer, Advanced EndocrinologyAnnual 2018
NSCI708, Graduate, Course, Guest Presenter, Special Topics in NeuroscienceSummer 2018
PHYSIO717, Graduate, Course, Lecturer, Circulatory PhysiologyFall 2017
PHYSIO611, Medicine, Lecture, Guest Presenter, Medical PhysiologySpring 2016
PHYSIO727, Graduate, Course, Lecturer, Physiological Applications of Molecular BiologyfAnnual 2015
ID709, Graduate, Course, Lecturer, Responsible Conduct of ResearchAnnual 2015 - 2016
PHYSIO725, Graduate, Lecture, Lecturer, Principles of PhysiologyAnnual 2014
PHYSIO611, Medicine, Small Group, Preceptor, Medical PhysiologyAnnual 2014
BCH740, Graduate, Lecture, Lecturer, Research Tools in Molecular BiologyAnnual 2013
PHYSIO625, Dentistry, Lecture, Lecturer, Principles of PhysiologyAnnual 2013

Directed Student Learning

Dissertation Committee Member, Advised: Subhi Younes2018 - Present
Dissertation Committee Member, Advised: Jason Engel2018 - Present
Dissertation Committee Member, Advised: Tyler Lomax2018 - Present
Supervised Research, Advised: Haley Murphy2018 - 2018
Dissertation Committee Chair, Advised: Kyle Moore2018 - Present
Dissertation Committee Member, Advised: Erika Guise2017 - Present
Dissertation Committee Member, Advised: Ashley Newsome2016 - 2018
Dissertation Committee Member, Advised: Marija Kuna2016 - 2018
Supervised Research, Advised: London Williams2016 - 2017
Dissertation Committee Chair, Advised: Adrian Eddy2016 - Present
Master's Thesis Committee Member, Advised: Jeremy McGowan2015 - 2017
Preceptor, Advised: William Stewart2015 - 2018
Supervised Research, Advised: Kevin Garman2014 - 2014
Supervised Research, Advised: Logan Wilson