David A. Cretella

David A. Cretella

Clinical Pharmacy Specialist

Department:
Antibiotic Stewardship Program

Email:
dcretella@umc.edu

Work Phone:
(601) 815-2721

Biography

Dr. Cretella received his doctor of pharmacy from the University of North Carolina and completed PGY1 pharmacy residency in Savannah GA, then a PGY2 infectious disease residency at the University of Mississippi medical center. Upon completion of residency, he entered a newly created position as an antimicrobial stewardship pharmacist at UMMC. He remains in that position with a practice that includes daily prospective audits with feedback and larger infectious disease projects. In 2018 he received an appointment in the division of infectious diseases. David lives with his wife and three children in Madison, Mississippi.

Education

University of North Carolina, PharmD, Pharmacy2013
University of Tennessee, BS, Chemistry2009

Specialty Certification Licensure

Certification, Infectious Disease Pharmacotherapy Board Certification, Board of Pharmacy Specialties06/2021 - 06/2028
Licensure, Registered Pharmacist, State of Georgia06/2024 - 12/2022
Licensure, Registered Pharmacist, State of North Carolina06/2013 - 12/2024
Licensure, Registered Pharmacist, State of Mississippi06/2014 - 12/2024

Current Positions

Assistant Professor, School of Medicine, Department of Medicine2018 - Present
Instructor, School of Pharmacy, Department of Pharmacy Practice07/2016 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Publications

Journal Article

Wingler MJB, Cretella DA, Parham J Navigating COVID-19 Experimental Treatments: A Comprehensive Review of the Medical Literature Journal of the Mississippi Medical Association, 2020 61(8), 184-1912020
Cretella DA, King ST, Parham J, Stover KR Change in meropenem utilization following the implementation of a targeted antimicrobial stewardship audit and feedback program Journal of the Mississippi Medical Association, 2017 8(5), 162-1672017
Roper S, Wingler MJB, Cretella DA, Antibiotic De-Escalation in Critically Ill Patients with Negative Clinical Cultures. Pharmacy (Basel, Switzerland), 2023 Jun 16;11(3)2023
Puzz L, Plauche EA, Cretella DA, Harrison VA, Wingler MJB, Evaluation of a Pediatric Community-Acquired Pneumonia Antimicrobial Stewardship Intervention at an Academic Medical Center. Antibiotics (Basel, Switzerland), 2023 Apr 19;12(4)2023
Vance MK, Cretella DA, Ward LM, Vijayvargiya P, Garrigos ZE, Wingler MJB, Risk Factors for Bloodstream Infections Due to ESBL-Producing Escherichia coli, Klebsiella spp., and Proteus mirabilis. Pharmacy (Basel, Switzerland), 2023 Apr 13;11(2)2023
Keck JM, Cretella DA, Stover KR, Wagner JL, Barber KE, Jhaveri TA, Vijayvargiya P, Garrigos ZE, Wingler MJB, Evaluation of an Antifungal Stewardship Initiative Targeting Micafungin at an Academic Medical Center. Antibiotics (Basel, Switzerland), 2023 Jan 17;12(2)2023
Markovich K, Wingler MJB, Stover KR, Barber KE, Wagner JL, Cretella DA, Analysis of the Clinical Impact of the BioFire FilmArray Meningitis Encephalitis Panel on Antimicrobial Use and Duration of Therapy at an Academic Medical Center. Diseases (Basel, Switzerland), 2022 Nov 20;10(4)2022
Wingler MJB, Cretella DA, Wagner JL, Barber KE, Bookstaver PB, Freeman L, Covington EW, Bland CM, Jones BM, Tran M, Stramel SA, Turner M, Childress D, Stover KR, Evaluation of Pharmacy Residency Recruitment and Interview Processes during the COVID-19 Pandemic (2020-2021 Application Cycle). Journal of the American College of Clinical Pharmacy : JACCP, 2022 Jul 20;2022
Hawkins BK, Barnard M, Barber KE, Stover KR, Cretella DA, Wingler MJB, Wagner JL, Diabetic foot infections: A microbiologic review. Foot (Edinburgh, Scotland), 2022 May;51:1018772022
Gunter SG, Wingler MJB, Cretella DA, Wagner JL, Barber KE, Stover KR, Intravenous versus Oral Step-Down for the Treatment of Staphylococcus aureus Bacteremia in a Pediatric Population. Pharmacy (Basel, Switzerland), 2022 Jan 15;10(1)2022
Esquer Garrigos Z, Wingler MJB, Svoronos PA, Vijayvargiya P, Goodman-Meza D, O'Horo JC, Navalkele BD, Cretella D, Frame IJ, Parham J, Lucar J, Increased rates of blood culture contamination during the coronavirus disease 2019 pandemic. Infection control and hospital epidemiology, 2022 Nov;43(11):1719-17212022
Lucar J, Wingler MJB, Cretella DA, Ward LM, Sims Gomillia CE, Chamberlain N, Shimose LA, Brock JB, Harvey J, Wilhelm A, Majors LT, Jeter JB, Bueno MX, Albrecht S, Navalkele B, Mena LA, Parham J, Epidemiology, Clinical Features, and Outcomes of Hospitalized Adults with COVID-19: Early Experience from an Academic Medical Center in Mississippi. Southern medical journal, 2021 Mar;114(3):144-1492021
Chastain DB, White BP, Cretella DA, Bland CM, Is It Time to Rethink the Notion of Carbapenem-Sparing Therapy Against Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Bloodstream Infections? A Critical Review. The Annals of pharmacotherapy, 2018 May;52(5):484-4922018
Cretella D, Barber KE, King ST, Stover KR, Comparison of susceptibility patterns using commercially available susceptibility testing methods performed on prevalent Candida spp. Journal of medical microbiology, 2016 Dec;65(12):1445-14512016
Keck JM, Wingler MJB, Cretella DA, Vijayvargiya P, Wagner JL, Barber KE, Jhaveri TA, Stover KR, Approach to fever in patients with neutropenia: a review of diagnosis and management. Therapeutic advances in infectious disease, 2022 Jan-Dec;9:20499361221138346
Tsai YV, Bookstaver PB, Kohn J, Justo JA, Childress D, Stramel S, Slain D, Tu P, Wingler MJB, Jones BM, Anderson DT, Seddon MM, Cretella DA, Eudy J, Winders H, Antosz K, Bailey P, Al-Hasan MN, The prevalence of gram-negative bacteria with difficult-to-treat resistance and utilization of novel β-lactam antibiotics in the southeastern United States. Antimicrobial stewardship & healthcare epidemiology : ASHE, 2024;4(1):e35
Stover KR, Hawkins BK, Keck JM, Barber KE, Cretella DA, Antifungal resistance, combinations and pipeline: oh my! Drugs in context, 2023;12
Wingler MJB, Cretella DA, Wagner JL, Barber KE, Bookstaver PB, Jones BM, Bland CM, Covington EW, Tran M, Stramel SA, Childress D, Turner M, Freeman L, Stover KR, Rethinking residency recruitment, application, and interview processes to benefit applicants and programs long-term. Journal of the American Pharmacists Association : JAPhA, 2022 Nov-Dec;62(6):1756-1760
Hawkins BK, Wingler MJB, Cretella DA, Barber KE, Stover KR, Wagner JL, An evaluation of antipseudomonal dosing on the incidence of treatment failure. SAGE open medicine, 2021;9:20503121211000927
Brock JB, Cretella DA, Parham JJ, An Antimicrobial Stewardship Intervention Improves Adherence to Standard of Care for Staphylococcus aureus Bloodstream Infection. Journal for healthcare quality : official publication of the National Association for Healthcare Quality, 2019 Nov Dec;41(6):e83-e89

Electronic Publications

David Cretella Interactive Case: Decreasing Blood Culture Contamination Rates American College of Clinical Pharmacy Infectious Disease Self-Assessment Program (IDSAP) Interactive Case IDSAP Critical Care Module2023

Presentations

Platform Presentations, Do We Need That Much Information? Rapid Respiratory Diagnostics, Division of Infectious Diseases, Jackson, MS03/2024
Poster Presentation, Azithromycin Dosing for Hospitalized Patients with Community Acquired Pneumonia, Vizient pharmacy network poster session, Virtual12/2023
Poster Presentation, Implementation of a Pharmacist/Physician Collaborative Practice Pilot for Patients with CAP and COPD Acute Exacerbations, ASHP Midyear, Orlando FL12/2023
Poster Presentation, Treatment of Pediatric Urinary Tract Infections at an Academic Medical Center, Vizient pharmacy network poster session, Virtual12/2023
Poster Presentation, Review of Oral Vancomycin for the Treatment of C. difficile Infections, Vizient pharmacy network poster session, Virtual12/2023
Platform Presentations, Oral Antimicrobial Therapy for Serious Infections, Division of Infectious Diseases, Jackson MS09/2023
Poster Presentation, Impact of a Direct Stewardship Intervention on Prescribing Practices for the Management of Uncomplicated Gram-Negative Bloodstream Infections, MAD-ID, Orlando FL05/2023
Poster Presentation, Impact of Removal of Default Durations and Pharmacist-Led Education On Discharge Antibiotic Prescribing in the Emergency Department, MAD-ID, Orlando, FL05/2023
State/Local Invited Seminars/Lectures, Applying Antimicrobial Stewardship to Critically Ill Patients, Mississippi Critical Care Conference (MCCC), Table 100 Conference Center, Flowood MS04/2023
Platform Presentations, Glucocorticoids for CAP. Have we Solved the Mystery?, Division of Infectious Diseases, Jackson MS03/2023
Platform Presentations, What Am I supposed to do with Antifungals?, Division of Infectious Diseases, Jackson, MS02/2023
Poster Presentation, Community Acquired Pneumonia Disease State Evaluation, Vizient annual meeting, Virtual12/2022
Poster Presentation, Temporal Trends in Antibiotic Use of New β-lactams for Gram-Negative Bacteria With Difficult-to-Treat Resistance in the Southeastern United States, IDSA ID Week, Washington DC10/2022
Platform Presentations, Is That TEE NEE-ded? Can a Scoring System Help?, Division of Infectious Diseases, Jackson MS06/2022
State/Local Invited Seminars/Lectures, COVID-19 Treatment Update: Winter 2021, Southwest MS Regional Medical Center (, Virtual2022
State/Local Invited Seminars/Lectures, COVID-19 in Winter 2021: Boosters, New Treatments and the Omicron Variant, Mississippi AETC, Virtual12/2021
Platform Presentations, Literature Update: COVID Corner, Division of Infectious Diseases, Jackson MS12/2021
Poster Presentation, Evaluation of Outpatient Antibiotic Prescribing for Upper Respiratory Infections at an Academic Medical Center, ASHP Midyear, Virtual12/2021
Poster Presentation, Evaluation of Gram-negative Bacteremias in Adult and Pediatric Patients at the University of Mississippi Medical Center., ASHP Midyear, Virtual12/2021
Poster Presentation, An Evaluation of Antibiotic Prescribing Patterns in Patients with COVID-19, ASHP Midyear, Virtual12/2021
Poster Presentation, Evaluation of Antibiotic Prescribing for Upper Respiratory Tract Infections in Outpatient Clinics Associated with an Academic Medical Center, ASHP Midyear Meeting, Virtual12/2021
Poster Presentation, Assessing Discontinuation of Antifungals after a Negative 1,3-Beta-D-Glucan Assay, ASHP Midyear Meeting, Virtual12/2021
Poster Presentation, Evaluation of MRSA-active Agents in Children Admitted to a Pediatric Intensive Care Unit, ASHP Midyear clinical meeting, Virtual12/2021
Poster Presentation, Antibiotic De-escalation in Critically Ill Patients with Negative Clinical Cultures, Vizient Annual Meeting, Virtual12/2021
State/Local Invited Seminars/Lectures, Treatment and Prevention of Coronavirus Disease 2019 (COVID-19) What do we know now ant what questions remain?, Mississippi Society of Health System Pharmacists annual meeting, Jackson MS07/2021
Platform Presentations, ASP Updates and Deep Dive Into the Biofire ME Panel, Division of Infectious Diseases, Jackson, MS04/2021
Platform Presentations, Literature Update: COVID Corner, Mississippi AETC, Virtual02/2021
Poster Presentation, Evaluation of the Impact of the Biofire FilmArray Meningitis/Encephalitis Panel (MEP) on Antimicrobial De-escalation, ASHP Midyear, Virtual12/2020
Poster Presentation, Appropriateness of Surgical Antimicrobial Prophylaxis in Total Knee and Hip Arthroplasty Post-Implementation of Institutional Guidelines, ASHP Midyear, Virtual12/2020
Poster Presentation, Retrospective Evaluation of Hospitalized Pediatric Patients with Acute Bacterial Skin and Skin Structure Infections at a Tertiary Academic Center, ASHP Midyear, Virtual12/2020
Poster Presentation, An Evaluation of the Methicillin-Resistant Staphylococcus aureus Nasal Screening in Patients with SSTIs, DFIs, and Bone and Joint Infections, ASHP Midyear, Virtual12/2020
Poster Presentation, Evaluation of the Biofire FilmArray Gastrointestinal Pathogen Panel: An Opportunity for Diagnostic Stewardship, ASHP Midyear, Virtual12/2020
Poster Presentation, Evaluation of Antibiotic Prescribing Patterns in Patients with Low Serum Procalcitonin Levels at a Tertiary Academic Medical Center, ASHP Midyear, Las Vegas, NV12/2019
Poster Presentation, Implementation of the Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Polymerase Chain Reaction (PCR) for Vancomycin De-escalation, ASHP Midyear, Las Vegas, NV12/2019
State/Local Invited Seminars/Lectures, Antimicrobial Stewardship and Infection Prevention and Control: A Collaborative Approach, Association for Professional in Infection Control in Epidemiology (MS), Pearl, MS11/2019
Poster Presentation, Treatment of Staphylococcus aureus Bacteremia in a Pediatric Population: A Retrospective Cohort Analysis, IDSA ID Week, Washington, DC10/2019
State/Local Invited Seminars/Lectures, Approaching Antibiotic Allergies, 2019 Advanced Practice Providers Conference, Jackson, MS09/2019
Poster Presentation, Impact of a Multidisciplinary Team on Reducing Hospital-onset Clostridioides difficile Infections at an Academic Medical Center, SHEA Annual Meeting, Boston, MA04/2019
Platform Presentations, The Good, The Bad, The Ugly: A Literature Update, Division of Infectious Diseases, Jackson, MS02/2019
Poster Presentation, Evaluation of Antibiotic Lock Therapy Use in Patients with Catheter Related Bloodstream Infections, ASHP Midyear, Anaheim, CA12/2018
Poster Presentation, Evaluation of Methicillin-Resistant Staphylococcus Aureus (MRSA) Nasal Colonization and Risk of MRSA Infection: An Opportunity for Stewardship, ASHP Midyear, Anaheim CA12/2018
State/Local Invited Seminars/Lectures, Antimicrobial Stewardship as a Component of Quality Improvement, UMMC Quality Improvement Conference, Jackson, MS11/2018
Platform Presentations, The Role of Negative Methicillin-Resistant Staphylococcus aureus Nasal Surveillance Swabs in Predicting the Need for Empiric Vancomycin Therapy In Intensive Care Unit Patients, Division of Infectious Diseases, Jackson MS03/2018
Platform Presentations, Gram Negative Bacteremia Duration of Therapy: A Literature Update, Division of Infectious Diseases, Jackson, MS2018
Poster Presentation, Automated Alerts Coupled with Antimicrobial Stewardship Intervention for Gram-Positive Bacteremia, ASHP Midyear, Orlando FL12/2017
State/Local Invited Seminars/Lectures, Don’t Panic! Applying the Principles of Rational Antibiotic Selection, Mississippi Pharmacists Association Consulting Seminar, Jackson, MS09/2017
Platform Presentations, Antibiotic Stewardship, Pharmacology, and More!, 2017 Advanced Practice Providers Conference, Pearl MS09/2017
Platform Presentations, Has monitoring procalcitonin changed antibiotic use in US ICUs, Division of Infectious Diseases, Jackson, MS05/2017
Platform Presentations, Non-Carbapenem Treatment of Infections Caused by Extended Spectrum Beta-Lactamase Producing Bacteria, Division of Infectious Diseases, Jackson, MS03/2017
Poster Presentation, Rate of Appropriate Management of Asymptomatic Bacteriuria at a Large, Academic Medical Center, Rho Chi Student Research Day, Oxford, MS03/2017
Platform Presentations, Impact of Reported Beta-Lactam Allergy on Inpatient Outcomes, Division of Infectious Disease, Jackson, MS12/2016
Platform Presentations, Rising Vancomycin Minimum Inhibitory Concentrations: Cause for Concern?, Division of Infectious Diseases, Jackson, MS09/2016
Poster Presentation, Prevalence of Candida Species and Comparison of Susceptibility Patterns Using Commercially Available Susceptibility Testing Methods, IDSA ID Week, New Orleans, LA09/2016
State/Local Invited Seminars/Lectures, Getting to the Bottom of the Bottle: Responding to Positive Blood Cultures, Mississippi Society of Health System Pharmacists annual meeting, Biloxi, MS07/2016
Platform Presentations, Update on Candidemia and Invasive Candidiasis, Division of Infectious Diseases, Jackson, MS04/2016
Platform Presentations, Clinical and Economic Impact of Antimicrobial Stewardship Interventions with the FilmArray BCID, Division of Infectious Diseases, Jackson, MS02/2016
Poster Presentation, Change in Meropenem Utilization Following the Implementation of a Targeted Antimicrobial Stewardship Audit and Feedback Program, ICAAC Annual Meeting, San Diego, CA09/2015
Platform Presentations, Epidemiology and Susceptibility Patterns of Candida Species Using Commercially Available Susceptibility Testing Methods, Mid-South Regional Pharmacy Residents Conference, Memphis, TN04/2015
Platform Presentations, Epidemiology and Susceptibility of Clinical Yeast at UMMC, Division of Infectious Diseases, Jackson, MS02/2015
Platform Presentations, FKS Mutant Candida Glabrata: Risk Factors and Outcomes in Patients with Candidemia, Division of Infectious Diseases, Jackson, MS2015
Poster Presentation, A Medication Utilization Review of Extended Treatment Duration with Piperacillin-Tazobactam at an Academic Medical Center, ASHP Midyear, Las Vegas, NV12/2012
Poster Presentation, Evaluation of Vancomycin Dosing in Patients with End Stage Renal Disease Receiving High Flux Hemodialysis in a Large Community Hospital, ASHP Midyear Meeting, New Orleans, LA12/2011

Professional Membership and Service

Infectious diseases society of America, Member2016 - 2023
Mississippi Society of Health-System Pharmacists, Member2015 - Present
American Society for Microbiology, Member2014 - 2016
Society of Infectious Disease Pharmacists, Member2014 - Present
American Society of Health Systems Pharmacists, Member2011 - 2023
North Carolina Association of Pharmacists, Member2011 - 2013
University of North Carolina Student Congress, Member2011 - 2012
Phi Delta Chi (Pharmacy), Officer, Other Officer2009 - 2013

Committee Service

THE UNIVERSITY HOSPITALS AND CLINICS-INFECTION PREVENTION, Member2023 - Present
Quality Improvement: MRSA2022 - Present
Perioperative antibiotic committee, Member2018 - 2021
Quality Improvement: C. difficile and MRSA, Member2017 - 2018
Medication Management, Member2016 - Present
PGY1 Pharmacy resident research committee, Member2016 - 2019
Quality Improvement: Hospital acquired infections, Member2016 - 2017
Antimicrobial Stewardship Committee, Co-Chair2015 - Present

Teaching Experience

Pharmacy, Lecture, Course Presenter, Infectious Disease ElectiveFall 2021

Directed Student Learning

Preceptor, Advised:2016 - Present

Fellows supervised

Infectious Disease Fellowship, Preceptor, 6 fellows supervised, Antimicrobial Stewardship06/2017 - Present

Residency Training

UMMC PGY2 Infectious Disease Pharmcy Residency, Preceptor2015 - Present
UMMC PGY1 Pharmacy Residency, Preceptor2015 - Present