John J. Correia, PhD
Professor Emeritus
Department:
SOM-Cell and Molecular Biology
Email:
jcorreia@umc.edu
Work Phone:
(601) 984-1522
Education
| University of Connecticut, Storrs, CT, PhD, Biophysics | 1981 |
| Vanderbilt University, Postgraduate Training, Microtubule Biochemistry | 1981 |
| Villanova University, Villanova, PA, BA, General Science | 1972 |
Current Positions
| Professor, School of Medicine, Department of Biochemistry | 07/1997 - Present |
| The University of Mississippi Medical Center Jackson, Mississippi 39216 | |
Academic Appointments or Other Previous Appointments
| Associate Professor, The University of Mississippi Medical Center, School of Medicine, Department of Biochemistry | 07/1992 - 06/1997 |
| Assistant Professor, The University of Mississippi Medical Center, School of Medicine, Department of Biochemistry | 11/1987 - 06/1992 |
Sponsored Program Funding
| Extramural, Systems Biology of Antimitotic Drugs and Chemotherapy, Charles Morgan Carraway and Joanne M. Carraway Charitable Foundation | 04/2007 - 03/2008 |
| Extramural, Structural Basis of Regulation of Interferon Regulatory Factor, NIH, 1 RO1 - PI: Kai Lin at U Mass Medical School | 07/2004 - 01/2008 |
| Extramural, Development of AUC Fluorescence Methods for Hetero-Protein Interactions, BITC (Biomolecular Interaction Technologies Center @ Univ. of NH) | 05/2004 - 04/2006 |
| Extramural, Basis of Phosphorylation in TGF- Signaling., NIH, 1 RO1 CA81106-01A2 -PI: Kai Lin at U Mass Medical School | 07/2003 - 06/2004 |
| Extramural, "Interaction of Antimitotics with Tubulin Isotypes, NSF | 05/1993 - 04/1998 |
| Extramural, "Dynamics of Microtubule Assembly/Disassembly, NIH | 12/1988 - 11/1993 |
Publications
Journal Article | |
| P. Holland Alday and John J. Correia "Macromolecular Interaction of Halichondrin B analogs Eribulin (E7389) and ER-076349 with Tubulin by Analytical Ultracentrifugation." Biochemistry, 48, 7927-7938. | 2009 |
| CORREIA, J. J., Alday, P.H., Sherwood, P. and Stafford, W. F. Effect of Kinetics on Sedimentation Velocity Profiles and the Role of Intermediates. Ed. Michael L. Johnson) Vol 467, Numerical Methods, 467:135-61 | 2009 |
| Steven S. Rosenfeld, Marilyn Van Duffelen, Will Parks, Christopher Beadle, John J. Corrreia, and Jun Xing THE ATPase Cycle of the Mitotic Motor CENP-E. JBC, 284, 32858–32868. | 2009 |
| George J. Turner, Shirisha Chittiboyina, Lauren Pohren, Kirk G. Hines, John J. Correia, and The Bacteriorhodopsin Carboxyl-Terminus Contributes to Proton Recruitment and Protein Stability. Biochemistry. 2009; in press | 2009 |
| Weijun Chen, Suvana S. Lam, Hema Srinath, Zhaozhao Jiang, John J CORREIA, Celia A. Schiffer, Katherine A. Fitzgerald, Kai Lin & William E. Royer Jr. Interferon regulatory factor activation revealed by the crystal structure of dimeric IRF-5 Nature Structural & Molecular Biol. 2008; 15, 1213-1220 | 2008 |
| Ashish Aggarwal, Anna Kruczynski, Anthony Frankfurter, John J. CORREIA and Sharon Lobert Murine Leukemia P388 Vinorelbine-Resistant Cell Lines Are Sensitive to Vinflunine Investigational New Drugs. 2008; 26, 319-330 | 2008 |
| Valeria Cucchiarelli, Laree Hiser, Hilda Smith, Anthony Frankfurter, Anthony Spano, β-Tubulin Isotype Classes II and V Expression Patterns in Nonsmall Cell Lung Carcinomas. Cell Motil. Cytoskel. 2008; 65, 675-685 | 2008 |
| S. S. Dignam, J. J. CORREIA, S. A. Nada, J. P. Trempe, J. D. Dignam Activation of the ATPase Activity of Adenoassociated Virus Rep68 and Rep78 Biochemistry. 2007; 46: 6364-6374 | 2007 |
| Montserrat Bosch, Kim Ho Diep Le, Beata Bugyi, John J. CORREIA, Louis Renault and Marie-France Carlier Analysis of the function of Spire in actin assembly and its synergy with formin and profiline Mol Biol Cell. 2007; 28:555-68 | 2007 |
| Anthony J. Spano, Frank S. Chen, Benjamin E. Goodman, Agnes E. Sabat, Martha N. Simon, Joseph S. Wall, John J. CORREIA, Wilson McIvor, William W. Newcomb, Jay C. Brown, Joel M. Schnur and Nikolai Lebedev In vitro assembly of a Prohead-like Structure of Rhodobacter capsulatus Gene Transfer Agent. Virology. 2007; 364: 95-102 | 2007 |
| S. Lobert, J.W. Ingram and J.J. CORREIA The Thermodynamics of Vinca Alkaloid-Induced Tubulin Spiral Formation. Biophys. Chem. 2007; Special Issue, Festschrift for Julian Sturtevant, 126: 50-58. | 2007 |
| S. Lobert and J.J. CORREIA “Methods for studying vinca alkaloid interaction with tubulin .” Humana Press, (Ed., Jin Zhou), Chapter 18, pp 261-280. | 2007 |
| L. Hiser, A. Aggarwal, R. Young, A. Frankfurter, A, Spano, J. J. CORREIA, and S. Lobert, “Correlation of Beta-Tubulin mRNA and Protein Levels in Twelve Human Cancer Cell Lines” Cell Motility & Cytoskeleton, 63, 41. | 2006 |
| B. Qin, C. Liu, H. Srinath, S. S. Lam, J. J. CORREIA, R. Derynck, K. Lin, Crystal Structure of IRF-3 in Complex with CBP Structure, 13, 1-9. | 2005 |
| . J. CORREIA, C. A. Sontag, W. F. Stafford and P. J. Sherwood, “Models for Direct Boundary Fitting of Indefinite Ligand-Linked Self-Association” in Analytical Ultracentrifugation: Techniques and Methods. (Ed. D. Scott, S. Harding and A. Rowe) pp 51-63. | 2005 |
| J. Li, J. J. CORREIA, L. Wang, J. O. Trent & J. B. Chaires “Not So Crystal Clear: The Structure of the Human Telomere G-quadruplex in Solution Differs from that Seen in the Crystal | 2005 |
| A.T. Mackey, C.A. Sontag, L.L. Satterwhite, J.J. CORREIA, and Susan P. Gilbert, “The ATPase Mechanism Behind the Microtubule-Based Motility of GST-Kar3” JBC, 279, 51354-61. | 2004 |
| A.T. Mackey, C.A. Sontag, L.L. Satterwhite, J.J. CORREIA, and Susan P. Gilbert “The ATPase Mechanism Behind the Microtubule-Based Motility of GST-Kar3” JBC, 279, 51354-61. | 2004 |
| CORREIA, J. J., and Stafford, W. F. (2009) Extracting equilibrium constants from kinetically limited reacting systems. (Ed. Michael L. Johnson) Vol 455, Biothermodynamics, Part A, pp. 419-46 | |
| Lyons DF, Le V, Kramer WH, Bidwell GL 3rd, Lewis EA, Raucher D, Correia JJ, Effect of basic cell-penetrating peptides on the structural, thermodynamic, and hydrodynamic properties of a novel drug delivery vector, ELP[V5G3A2-150]. Biochemistry, 2014 Feb 18;53(6):1081-91 | 2014 |
| Reilly SM, Lyons DF, Wingate SE, Wright RT, Correia JJ, Jameson DM, Wadkins RM, Folding and hydrodynamics of a DNA i-motif from the c-MYC promoter determined by fluorescent cytidine analogs. Biophysical journal, 2014 Oct 7;107(7):1703-11 | 2014 |
| Lyons DF, Lary JW, Husain B, Correia JJ, Cole JL, Are fluorescence-detected sedimentation velocity data reliable? Analytical biochemistry, 2013 Jun 15;437(2):133-7 | 2013 |
| Lyons DF, Le V, Bidwell GL 3rd, Kramer WH, Lewis EA, Raucher D, Correia JJ, Structural and hydrodynamic analysis of a novel drug delivery vector: ELP[V5G3A2-150]. Biophysical journal, 2013 May 7;104(9):2009-21 | 2013 |
| Alberico EO, Lyons DF, Murphy RJ, Philip JT, Duan AR, Correia JJ, Goodson HV, Biochemical evidence that human EB1 does not bind preferentially to the microtubule seam. Cytoskeleton (Hoboken, N.J.), 2013 Jun;70(6):317-27 | 2013 |
| Kumar A, Paslay LC, Lyons D, Morgan SE, Correia JJ, Rangachari V, Specific soluble oligomers of amyloid-β peptide undergo replication and form non-fibrillar aggregates in interfacial environments. The Journal of biological chemistry, 2012 Jun 15;287(25):21253-64 | 2012 |
| Correia JJ, Stafford WF, Sedimentation Velocity: A Classical Perspective. Methods in enzymology, 2015;562:49-80 | |
| Acar S, Carlson DB, Budamagunta MS, Yarov-Yarovoy V, Correia JJ, Niñonuevo MR, Jia W, Tao L, Leary JA, Voss JC, Evans JE, Scholey JM, The bipolar assembly domain of the mitotic motor kinesin-5. Nature communications, 2013;4:1343 | |
Review Article | |
| M.A. Jordan, S.B. Horowitz, S. Lobert, J.J. CORREIA Exploring the Mechanisms of Action of the Novel Microtubule Inhibitor Vinflunine. Seminars in Oncology. 2208; 35, S6-S12 | 2008 |
Thesis | |
| J.J. CORREIA Analytical Ultracentrifuge Techniques for Unstable Protein Systems PhD Thesis, University of Connecticut | 1981 |
Book Chapter | |
| J. J. CORREIA and S. Lobert Molecular Mechanisms of Micotubule Acting Cancer Drugs in Microtubule Targets in Cancer Therapy, Humana Press (Ed., Tito Fojo) 2008 | 2008 |
| S. Lobert and J.J. CORREIA Methods for studying vinca alkaloid interaction with tubulin. Humana Press, (Ed., Jin Zhou), Chapter 18, pp 261-280 | 2007 |
Presentations
| "The use of AUC (Analytical Ultracentrifugation) to characterize drug delivery systems." October, 12 2012., Mississippi State University, Department of Chemistry | 10/2012 |
| Scientific Presentations, "FDS Hydrodynamic Characterization of an Elastin-Like Drug Delivery Peptide in Plasma." April 13, 2012., Notre Dame University, Department of Chemistry and Biochemistry | 04/2012 |
| Scientific Presentations, "FDS Hydrodynamic Characterization of an Elastin-Like Drug Delivery Peptide in Plasma." Dec 1, 2011, Univ Colorado Anschutz Medical Campus, Department of Pharmaceutical Sciences | 12/2011 |
| National and International Invited Seminars/Lectures, Introduction to session on Biothermodynamics and Disease: From Free Energy to the Clinic, 25th Gibbs Conference on Biothermodynamics | 09/2011 |
| National and International Invited Seminars/Lectures, UMC Biochemistry Retreat, Jackson, MS | 09/2011 |
| National and International Invited Seminars/Lectures, FDS Hydrodynamic Characterization of an Elastin-Like Drug Delivery Peptide in Plasma, UNH AUC Workshop, Durham, UNH | 07/2011 |
| National and International Invited Seminars/Lectures, The Use of Fluorescence Detection in AUC studies: Advantages and Challenges, Mississippi Biophysical Consortium, Oxford, MS | 06/2011 |
| National and International Invited Seminars/Lectures, Progress on the Biophysics of Anti-Cancer Drugs, UMMC, Department of Biochemistry | 11/2010 |
| National and International Invited Seminars/Lectures, The Use of Fluorescence Optics in Analytical Ultracentrifugation Studies: A Goal of In Vivo Biophysics, University Southern Mississippi | 10/2010 |
| National and International Invited Seminars/Lectures, The Use of Simulations in Understanding AUC Analysis Methods, BBRI AUC Workshop, Boston, MA | 05/2010 |
| National and International Invited Seminars/Lectures, Simulation and Investigation of Macromolecular Interactions by AUC: Drugs, Kinetics and Fluorescence Detection, Johns Hopkins University, Baltimore, MD | 05/2010 |
| National and International Invited Seminars/Lectures, Macromolecular Interaction of Halichondrin B Analogues Eribulin (E7389) and ER-076349 with Tubulin by Analytical Ultracentrifugation, 125th The Svedberg Anniversary, 18th International AUC Conference, Uppsala, Sweden | 09/2009 |
| National and International Invited Seminars/Lectures, Anti-Mitotic Drugs: Do In Vitro Measurements Translate to In Vivo Mechanisms, University of Colorado, Boulder, CO | 05/2009 |
| National and International Invited Seminars/Lectures, Energetics, Regulation and Modeling of Mitotic Microtubule Complexes: Windows into the Biology of Anti-Mitotic Drugs, Medical College of South Carolina, Charleston, SC | 04/2008 |
| Scientific Presentations, Energetics, Regulation and Modeling of Mitotic Microtubule Complexes: Windows into the Biology of Anti-Mitotic Drugs., Medical College of South Carolina, Medical College of South Carolina, Charleston, SC | 04/2008 |
| National and International Invited Seminars/Lectures, How to Integrate Clinical Correlations into Medical Biochemistry, Medical Biochemistry Education Strategies Workshop, Myrtle Beach, SC | 04/2008 |
| National and International Invited Seminars/Lectures, Energetics, Regulation and Modeling of Mitotic Microtubule Complexes, RASMB Gordon Research Conference, Ventura, CA | 01/2008 |
| National and International Invited Seminars/Lectures, Vinflunine microtubule binding/ microtubule dynamics, Vinflunine Basic Science Summit, hosted by Bristol-Myers Squibb and Pierre Fabre Oncology, Paris, France | 03/2007 |
| National and International Invited Seminars/Lectures, Comparative AUC Studies on Tubulin:Stathmin and Actin:Spire Complexes, CNRS, Gif sur Yvette, France | 03/2007 |
| National and International Invited Seminars/Lectures, The Effect of Kinetics on Sedimentation Velocity Profiles: The Role of Intermediates, 15th International AUC Workshop and Symposium, University College London | 04/2006 |
| National and International Invited Seminars/Lectures, E7389 suppresses Tubulin assembly and binding of Stathmin: biophysical characterization by quantitative sedimentation velocity, Eisai, Andover, MA | 03/2006 |
| National and International Invited Seminars/Lectures, The Use of Multi-wavelength and Fluorescence AUC: Case Studies of Tubulin Regulatory Factors and Antimitotic Drugs, 19th Gibbs Conference on Biothermodynamics | 10/2005 |
| National and International Invited Seminars/Lectures, The Use of Muti-wavelength and Fluorescence AUC in Drug Discovery: Studies on Tubulin, Regulatory Factors and Antimitotic Drugs, Louisville University | 08/2005 |
| National and International Invited Seminars/Lectures, Interaction of Stathmin-Tubulin-Vinblastine by Multi-wavelength and Fluorescence AUC Techniques, EMBL, Heidelberg, Germany | 06/2005 |
| National and International Invited Seminars/Lectures, The Mechanism of Action of AntiMitotic Drugs: Implications for Drug Discovery, Department Pharmacognosy, Univ of Mississippi, Oxford, MS | 04/2005 |
| National and International Invited Seminars/Lectures, The Use of XLA- and XLF-AUC Techniques to Dissect the Energetics of Tight Interactions Between Tubulin, Drugs and Regulatory Proteins, Amgen, Los Angeles, CA | 01/2005 |
| National and International Invited Seminars/Lectures, The Use of Fluorescence Optics to Investigate Interactions Between Tubulin, Regulatory Factors and Anti-Mitotc Drugs, BITC annual meeting, Los Angeles, CA | 01/2005 |
| National and International Invited Seminars/Lectures, The Use of Multi-Wavelength and Fluorescence AUC Techniques to Measure the Energetics of Tight Interactions Between Tubulin, Drugs and Regulatory Proteins, UC Santa Barbara | 01/2005 |
| National and International Invited Seminars/Lectures, Direct Boundary Fitting of Hetero-Association, Finally!, NAUCF Workshop Symposium, Storrs, CT | 06/2004 |
| National and International Invited Seminars/Lectures, Direct Boundary Fitting of Indefinite Ligand-Linked Self-Association: New Insights, European UK AUC meeting, Oxford, UK | 04/2004 |
| National and International Invited Seminars/Lectures, Quantifying Ternary Interactions Between Antimitotic Drugs, Tubulin and Regulatory Proteins: A Window on Drug Resistance, The University of Texas Medical Branch, Galveston, TX | 03/2004 |
| National and International Invited Seminars/Lectures, Model Building and Analysis Methods for Indefinite Associating Systems, NAUCF Workshop Symposium, Storrs, CT | 06/2003 |
| National and International Invited Seminars/Lectures, Do Tubulin Drugs Disrupt or Mimic Interactions with Regulatory Factors Through Ternary Complex Formation?, Madrid, Spain, CIB | 05/2003 |
| National and International Invited Seminars/Lectures, Using AUC to Study Anti-Mitotic Drugs and the Microtubule Interactome, NAUCF Workshop Symposium, Storrs, CT | 06/2002 |
| National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets.” Or “Antimitotic Drugs and New Targets: From Biophysics to Cellular Effectiveness, Department of Cell Biology and Biophysics, University of Missouri - Kansas City | 04/2002 |
| National and International Invited Seminars/Lectures, The Regulation and Energetics of Receptor Mediated Smad Trimerization, 15th Gibbs Conference on Biothermodynamics | 09/2001 |
| National and International Invited Seminars/Lectures, Tall Tales about the Power of the Almighty Analytical Ultracentrifuge, NAUCF Workshop Symposium, in memory of Todd Schuster, Storrs, CT | 05/2001 |
| National and International Invited Seminars/Lectures, Better (Anti-Cancer) Drugs Through (Bio)Chemistry, UMMC, Campus Research Seminar, Jackson, MS | 05/2001 |
| National and International Invited Seminars/Lectures, What Can Fluorescent Vinca Alkaloids Teach Us?, Castres, France, Pierre Fabre | 04/2001 |
| National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets, French-American Colloquium on the Cytoskeleton and Human Disease, Marseille, France | 04/2001 |
| National and International Invited Seminars/Lectures, The Energetics of Antimitotic Drugs: New Approaches and New Targets, Structure/Function Seminar Series, Univ. Alabama Birmingham | 03/2001 |
| National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets, Department of Pharmacology, Univ. of Mass. Med. School | 02/2001 |
| National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets, Department of Molecular Biology and Molecular Biophysics Program Project Seminar Series, Vanderbilt University | 02/2001 |
| National and International Invited Seminars/Lectures, The Mechanism of Antimitotic Drugs and the Role of Hidden and New Targets, Department of Biology, Georgia Tech, Atlanta, GA | 10/2000 |
| National and International Invited Seminars/Lectures, The Interactions of Vinca Alkaloids with Tubulin and Microtubules: Biophysical Data and Implications for Cancer Chemotherapy, Dept Chemistry, Oxford, MS | 04/2000 |
| National and International Invited Seminars/Lectures, The interaction of tubulin heterodimers with kinesin motor domains: methodology, nucleotide dependence & implications for microtubule dynamics, EMBL, Heidelberg, Germany | 03/1999 |
| National and International Invited Seminars/Lectures, Energetics of Chemotherapeutic Vinca Alkaloids Through Analytical Ultracentrifugation: Implications for Drug Design, Wurzburger Symposium, University of Heidelberg, Heidelberg, Germany | 03/1999 |
| National and International Invited Seminars/Lectures, New Techniques For The Analysis of Hetero-associating Systems, Analytical Ultracentrifuge Workshop at the NSF National Analytical Ultracentrifuge Facility, Univ. of Conn., Storrs, Ct | 03/1999 |
| National and International Invited Seminars/Lectures, Energetics of Chemotherapeutic Vinca Alkaloids Through AUC: Implications for Drug Design, 2nd Beckman Symposium, Seattle, WA | 09/1998 |
| National and International Invited Seminars/Lectures, The Interactions of Vinca Alkaloids with Tubulin and Microtubules: Biophysical Data and Implications for Cancer Chemotherapy, Miss State | 04/1998 |
| National and International Invited Seminars/Lectures, Energetics of Vinca Alkaloid Tubulin and Tubulin Kinesin Motor Domain Interactions, Department of Pharmacology, UT - SW Medical Center | 03/1998 |
| National and International Invited Seminars/Lectures, The Analysis of Interacting Systems by Sedimentation Velocity, Analytical Ultracentrifuge Workshop at the NSF National Analytical Ultracentrifuge Facility, Univ. of Conn., Storrs, Ct | 03/1998 |
| National and International Invited Seminars/Lectures, Biophysical Studies of Vinca Alkaloid -Tubulin/Microtubule Interactions: Mechanistic and Clinical Implications, Univ. Of Miss. Medical Center, Department of Physiology and Biophysics | 02/1998 |
| National and International Invited Seminars/Lectures, Analysis of Weight Average Sedimentation Velocity Data, 1st Beckman Symposium, Galveston, TX | 11/1997 |
| National and International Invited Seminars/Lectures, The Use of Analytical Ultracentrifugation to Extract the Energetics of Vinca Alkaloid Tubulin Interactions, 3rd Annual Beckman Seminar, Univ. of Texas Health Science Center, San Antonio, TX. | 04/1997 |
| National and International Invited Seminars/Lectures, Quantitative Interpretation of Weight Average Sedimentation Velocity Data, 10th Symposium on Analytical Ultracentrifugation, University of Regensberg, Regensberg, Germany | 03/1997 |
| National and International Invited Seminars/Lectures, The Quantitative Interpretation of Weight Average Sedimentation Velocity Data, Analytical Ultracentrifuge Workshop at the NSF National Analytical Ultracentrifuge Facility, Univ. of Conn., Storrs, Ct | 03/1997 |
| National and International Invited Seminars/Lectures, Sedimentation Studies on Kinesin and NCD Motor Domain Constructs, Biophysical Society Meeting, New Orleans, LA | 02/1997 |
| National and International Invited Seminars/Lectures, Sedimentation Velocity Studies of the Vinca Alkaloid Induced Self Association of Tubulin, SPIE's International Symposium, BIOS'97, Biomedical Optics, San Jose, CA | 02/1997 |
| National and International Invited Seminars/Lectures, Sedimentation Velocity Studies of the Vinca Alkaloid Induced Self Association of Tubulin and Tubulin Isotypes, 10th Annual Gibbs Conference on Biothermodynamics, Carbondale, Il | 10/1996 |
| National and International Invited Seminars/Lectures, Sedimentation Velocity and Kinetic Studies on the Interaction of Vinca Alkaloids with Tubulin and B Tubulin Isotypes, Texas Medical Center, Houston, TX. | 04/1996 |
| National and International Invited Seminars/Lectures, Interaction of Vinca Alkaloids with Tubulin, Analytical Ultracentrifuge Workshop at the NSF National Analytical Ultracentrifuge Facility, Univ. of Conn., Storrs, Ct | 03/1996 |
| National and International Invited Seminars/Lectures, What Have Nonhydrolyzable GTP Analogs Taught us About Microtubule Assembly and Structure?, American Society for Cell Biology, Symposium on GTPases | 12/1995 |
| National and International Invited Seminars/Lectures, The Interaction of Vinca Alkaloids with Tubulin by Analytical Ultracentrifugation, A meeting on The Cytoskeleton and Cancer, Ile des Embiez, France | 09/1995 |
| National and International Invited Seminars/Lectures, The Interaction of Vinca Alkaloids with Tubulin by Analytical Ultracentrifugation: Clinical Implications, CNRS, Gif sur Yvette, France | 09/1995 |
| National and International Invited Seminars/Lectures, Vinblastine Induced and Divalent Cation Induced Self Association of Tubulin and Tubulin Isotypes, Symposium on Analytical Ultracentrifugation, Berlin, Germany | 03/1995 |
| National and International Invited Seminars/Lectures, Analytical Ultracentrifugation: A 'New' Technique for the Investigation of Macromolecular Association, Department of Biochemistry, University of Mississippi Medical Center | 02/1995 |
| National and International Invited Seminars/Lectures, Microtubule Assembly and the Role of Nucleotides, Tubulin Isotypes, MAPs and Antimitotic Drugs, Department of Biochemistry, Louisiana St. School of Medicine, Shreveport, LA | 11/1994 |
| National and International Invited Seminars/Lectures, The Interaction of Tubulin With Vanadate: Photoirradiation and Microtubule Polymerization Studies, Department of Medicinal Chemistry and Pharmacognosy, University of Mississippi | 04/1993 |
| National and International Invited Seminars/Lectures, Structural Probes of Microtubule Dynamics, Department of Physiology, University of Mississippi Medical Center | 05/1992 |
| National and International Invited Seminars/Lectures, Structural Probes of Microtubule Dynamics, Department of Physiology, University of Mississippi Medical Center | 10/1991 |
| National and International Invited Seminars/Lectures, Structural Studies on the Role of Divalent Cations in Microtubule Dynamics, University of Illinois at Chicago, Chicago, IL | 10/1991 |
| National and International Invited Seminars/Lectures, Error Propagation and Parameter Determination in Fitting Binding Data to the Exclusion Model, 4th Southeast DNA Symposium, October, 1990, University of Mississippi, Oxford, MS | 10/1990 |
| National and International Invited Seminars/Lectures, Tubulin Microtubule Dynamics: The Role of Metals and Nucleotides, Yoknapatawpha Conference on Biomolecular Science, University of Mississippi, Oxford, MS | 11/1989 |
| National and International Invited Seminars/Lectures, Mg+2 Dependence of Guanine Nucleotide Binding to Tubulin, Meeting On The Cytoskeleton, Oxford, England | 10/1988 |
| National and International Invited Seminars/Lectures, The Role of Divalent Cations in Microtubule Assembly and Dynamics, Mississippi State University, Starkville, MS | 03/1988 |
Professional Membership and Service
| Gibbs Conference on Biothermodynamics, Officer, Treasurer | 2010 - Present |
| Mississippi Biophysical Consortium, Meeting Organizer | 2008 - Present |
| Academic Appointment - University of Mississippi, Oxford, Joint Appointment | 2006 |
| Beckman XLA/XLI Analytical Ultracentrifuges, Ad Hoc Member, NIH Shared Instrumentation Study Section for Beckman XLA/XLI Analytical Ultracentrifuges | 2002 - 2003 |
| Gibbs Society of Biological Thermodynamics, Inc, President Elect, President Elect of the Gibbs Society of Biological Thermodynamics, Inc | 2001 - 2003 |
| Beckman XLA Analytical Ultracentrifuges, Ad Hoc Member, NIH Shared Instrumentation Study Section for Beckman XLA Analytical Ultracentrifuges | 1993 - 1995 |
| Gibbs Society of Biological Thermodynamics, Inc, Member, Gibbs Society of Biological Thermodynamics, Inc | 1991 - Present |
| Academic Appointment - Vanderbilt University, Research Insructor of Molecular Biology | 1985 - 1987 |
| American Association for the Advancement of Science, Member | |
| American Heart Association, Reviewer, Grant Proposal | |
| American Society for Cell Biology, Member | |
| Analytical Biochemistry, Reviewer, Journal Article | |
| Association of Biochemistry Course Directors, Member | |
| BBA, Reviewer, Journal Article | |
| Biochemistry, Reviewer, Journal Article | |
| Biophysical Journal, Reviewer, Journal Article | |
| Biophysical Society, Member | |
| Biopolymers, Reviewer, Journal Article | |
| European J. Medicinal Chemistry, Reviewer, Journal Article | |
| J. Biological Chemistry, Reviewer, Journal Article | |
| J. Medicinal Chemistry, Reviewer, Journal Article | |
| J. Mol. Biol., Reviewer, Journal Article | |
| J. Molecular Biology, Reviewer, Journal Article | |
| J. Neuroscience, Reviewer, Journal Article | |
| J. Theor. Biol., Reviewer, Journal Article | |
| Molecular Pharmaceutics, Reviewer, Journal Article | |
| NASA, Reviewer, Grant Proposal | |
| Nature Structural & Molecular Biology, Reviewer, Journal Article | |
| Nature, Reviewer, Journal Article | |
| NSF, Reviewer, Grant Proposal | |
| 25th Annual Gibbs Conference, Co-Organizer, 25th Annual Gibbs Conference on Biothermodynamics, September, Carbondale, Il | 2011 |
| Biophysical Chemistry, Co-Editor, Special Issue in Honour of 25th Annual Gibbs Conference on Biothermodynamics, Biophysical Chemistry | 2011 |
| Methods in Cell Biology, Co-Editor, Methods in Cell Biology, Vol 95, Microtubules, in vitro | 2010 |
| Methods in Cell Biology, Co-Editor, Methods in Cell Biology, Vol 89, Biophysical Tools for Biologists, Volume 2, in vivo Techniques | 2009 |
| NIH Shared Instrumentation Study Section, Ad Hoc Member, NIH Shared Instrumentation Study Section for Beckman XLA/XLI Analytical Ultracentrifuges, CD's and purification systems | 2009 |
| Methods in Cell Biology, Co-Editor, Methods in Cell Biology, Vol 84, Biophysical Tools for Biologists, Volume 1, in vitro Techniques, pp. 1-972 | 2008 |
| Beckman XLA/XLI Analytical Ultracentrifuges, Ad Hoc Member, NIH Shared Instrumentation Study Section for Beckman XLA/XLI Analytical Ultracentrifuges | 2006 |
| American Heart Association - National Center, Attendee, Meeting, BASIC 1 (Basic Cell & Molecular Biology 1) Study Group, Chicago, IL | 2005 |
| NIH Panel, Ad Hoc Member, NIH Panel on Continued Development and Maintenance of Bioinformatics and Computational Biology Software | 2005 |
| American Heart Association - National Center, Attendee, Meeting, BASIC 1 (Basic Cell & Molecular Biology 1) Study Group, Dallas, TX | 2005 |
| Biophysical Chemistry, Co-Editor, Special Issue in Honour of David Yphantis, Vol 108 | 2004 |
| Biophysical Society Meeting, Workshop Organizer, Hetero-Association Methods: Quantifying Reversible Macromolecular Association, at Biophysical Society Meeting in San Antonio | 2003 |
| Awards Committee, 2nd Beckman Symposium, Committee Member, Awards Committee, 1st Beckman Symposium | 1998 |
| Biophysics Society, Workshop Organizer, Analytical Ultracentrifuge Applications Workshop at the 1997 Biophysics Society Meeting | 1997 |
| Awards Committee, 1st Beckman Symposium, Committee Chair, 1st Beckman Symposium | 1997 |
| 11th Annual Gibbs Conference, Co-Organizer, 11th Annual Gibbs Conference on Biothermodynamics | 1997 |
| BRSG Study Section, Ad Hoc Member, BRSG Study Section, Univ. of Mississippi | 1992 |
Committee Service
| Peterson’s Guide Committee | 2001 - 2009 |
| Graduate Student Recruitment Committee, Chair | 2001 - 2005 |
| Biochemistry Search Committee for Faculty Positions | 2000 - 2002 |
| Course Coordinators Manual Subcommittee, Chair | 1998 - 2001 |
| Course Evaluation Subcommittee, Chair | 1998 - 2001 |
| CC Evaluation Subcommittee, Member | 1997 - 2000 |
| School Of Medicine - Curriculum, Member | 1997 - 2000 |
| Biochemistry Committee on Graduate Curriculum, Chair | 1992 - 1999 |
| Biochemistry Poster Committee, Member | 1989 - 2001 |
| Biochemistry Graduate Student Guidelines Committee, Member | 1989 - 1997 |
| Information Technology Subcommittee of the LCME Self Study | |
| Research Subcommittee of the LCME Self Study | |
| Faculty Senate Subcommittee on University Research Brochure, Chair |
Other Service
| Information Systems Strategic Planning Report - Basic Science Working Group | 12/2000 - 2001 |
| Academic Appointment, Professor of Biochemistry | 07/1997 - Present |
| UMMC Analytical Ultracentrifuge Center, Director | 1995 - Present |
| Medical Biochemistry, 610, Course Coordinator | 1995 - 2007 |
| Academic Appointment, Associate Professor of Biochemistry | 07/1992 - 06/1997 |
| Faculty Senate | 1992 - 1995 |
| Graduate Biochemistry, Course Coordinator | 1990 - 2008 |
| Biochemistry Journal Club, Coordinator | 1988 - 1993 |
| Academic Appointment, Assistant Professor of Biochemistry | 11/1987 - 06/1992 |
Teaching Experience
| Course, Medical Biochemistry 610 | |
| Course, Physical Biochemistry | |
| Course, Portal Biochemistry | |
| Small Group, Proteomics, Structural Proteomics and Bioinformatics: New | Winter 2002 |
| Small Group, Concepts in Linkage and Cooperativity | Winter 2000 |
| Small Group, Molecular Motors | Fall 1996 |
| Lecture, Lecturer, Analytical Ultracentrifugation/XLA Workshop for Shared Instrumentation Grant | 1995 |
| Course, Proteins | 1993 |
| Small Group, Cooperativity | Spring 1993 |
| Small Group, Microtubules and Mitosis | Winter 1991 |
| Small Group, Macromolecular Assembly | Spring 1989 |
Directed Student Learning
| Doctoral Advisory Committee Member, Advised: Daniel Lyons | |
| Doctoral Advisory Committee Member, Advised: Thomas Flanagan | |
| Doctoral Advisory Committee Member, Advised: Andrew Gilder | |
| Doctoral Advisory Committee Member, Advised: Payal Vayas | |
| Doctoral Advisory Committee Chair, Advised: Holland Alday | |
| Doctoral Advisory Committee Member, Advised: Eric George | |
| Master's Thesis Committee Member, Advised: Valeria Cucchiarelli | |
| Doctoral Advisory Committee Member, Advised: Asish Aggarwal | |
| Doctoral Advisory Committee Member, Advised: Dan Yellajoshyula | |
| Doctoral Advisory Committee Member, Advised: Xiaochun Shi | |
| Doctoral Advisory Committee Member, Advised: Alka Prasad | |
| Doctoral Advisory Committee Member, Advised: Jing Li | |
| Doctoral Advisory Committee Member, Advised: Patrick Kyle | |
| Doctoral Advisory Committee Member, Advised: Kiranan Chatti | |
| Doctoral Advisory Committee Member, Advised: Nian Huang | |
| Doctoral Advisory Committee Chair, Advised: Chris Sontag | |
| Doctoral Advisory Committee Member, Advised: Moonkyu Kang | |
| Doctoral Advisory Committee Member, Advised: Sid De | |
| Master's Thesis Committee Member, Advised: Nancy Stubbs | |
| Doctoral Advisory Committee Member, Advised: Kamini Hingorani | |
| Doctoral Advisory Committee Member, Advised: Meylssa Bratton | |
| Doctoral Advisory Committee Member, Advised: Akash Gunjan | |
| Doctoral Advisory Committee Member, Advised: Zhenyu Zhu | |
| Doctoral Advisory Committee Chair, Advised: Bojana Vulevic | |
| Doctoral Advisory Committee Member, Advised: Fenfei Leng | |
| Doctoral Advisory Committee Member, Advised: Reid Bishop | |
| Master's Thesis Committee Member, Advised: Oca Cossio | |
| Doctoral Advisory Committee Chair, Advised: Bettye Sue Hennington | |
| Doctoral Advisory Committee Member, Advised: Stan Smith | |
| Doctoral Advisory Committee Member, Advised: Harold Brooks | |
| Doctoral Advisory Committee Member, Advised: T.K. Harris | |
| Doctoral Advisory Committee Member, Advised: Dong Chul Suh | |
| Doctoral Advisory Committee Member, Advised: Julio Herrera | |
| Doctoral Advisory Committee Member, Advised: Tamba Dunbar |