Pier Paolo Claudio

Pier Paolo Claudio

Professor

Department:
SOM-Pharmacology/Toxicology

Email:
pclaudio@umc.edu

Work Phone:
(601) 984-1600

Biography

Dr. Pier Paolo Claudio is a Professor of Pharmacology and Toxicology at the University of Mississippi Medical Center (UMMC), where he also holds appointments in Radiation Oncology and Maxillofacial Surgery. He serves on the Cancer Institute Research Advisory Committee and chairs the Oversight Subcommittee of the Intellectual Property Committee. Dr. Claudio earned his MD and doctoral degrees *summa cum laude* from the University of Naples Frederick II. His research focuses on innovative cancer therapies, including ultrasound-guided gene delivery and the ChemoID drug response assay, both protected by multiple U.S. and international patents. He has secured over $21 million in research funding and published nearly 200 peer-reviewed papers. His ChemoID assay has been validated in multi-institutional clinical trials and recently received FDA Breakthrough Device Designation for glioblastoma. Dr. Claudio bridges basic and clinical cancer research across UMMC and the University of Mississippi, advancing precision oncology. He has taught cancer biology, translational medicine, and radiobiology to medical, graduate, and resident students since 1998. He is Editor-in-Chief of the *International Journal of Translational Medicine* and serves on several editorial boards. His career reflects a dedication to translating laboratory discoveries into meaningful clinical applications.

Education

Massachusetts Institute of Technology, Certification, Drugs and Medical Device Development2023
University of Naples "Federico II", PhD, Surgery1994
University of Naples "Federico II", Residency, Surgery1994
University of Naples "Federico II", MD, Medicine1989

Specialty Certification Licensure

Certification, Strategies for Drugs and Device Development, MIT06/2023 - Present

Current Positions

Professor, School of Medicine, Department of Pharmacology / Toxicology2023 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Professor, University of Mississippi, School of Pharmacy, Department of BioMolecularSciences07/2015 - 2023
Director, Marshall University, School of Medicine, Department of Translational Genomics Research Institute (TGRI)2009 - 12/2015
Associate Professor, Marshall University, School of Medicine, Department of Biochemistry and Microbiology2006 - 12/2015
Director, Temple University, School of Medicine, Department of Molecular Therapeutics Program2002 - 12/2006
Associate Professor, Temple University, School of Medicine, Department of Biology2002 - 12/2006
Associate Professor, Thomas Jefferson University, School of Medicine, Department of Pathology2000 - 12/2002
Assistant Professor, University of Naples Federico II, School of Medicine, Department of Head & Neck Surgery1998 - 12/2004
Assistant Professor, Thomas Jefferson University, School of Medicine, Department of Pathology1998 - 12/2000
Instructor, Thomas Jefferson University, School of Medicine, Department of Pathology1996 - 12/1998

Sponsored Program Funding

Extramural, Functional Precision Medicine Assay for Brain Metastasis, DOD01/2026 - 12/2030
Extramural, In vitro Production of Red Blood Cells for Transfusion Readiness, DOD01/2026 - 12/2030
Extramural, In vitro Production of Red Blood Cells for Transfusion Readiness, NIH12/2025 - 01/2029
Intramural, Personalized Functional Medicine Testing for Unresectable Glioblastoma with Unmethylated MGMT Promoter, CCRI Catalyst Award Fund08/2025 - 07/2026
Extramural, Antibody delivery for immunotherapy, Vesselon01/2025 - 12/2026
Intramural, Small scale Red Blood Cells Production and Characterization, MCCTR01/2024 - 12/2025
Extramural, Preclinical study on a new paclitaxel formulation (ART207), in Cancer Stem Cells (CSCs) and Bulk of Tumor Cells from patient-derived cell lines of ovarian, breast colon, pancreas, and lung cancer origin., Romolus Therapeutics08/2023 - 12/2023
Extramural, Preclinical study on a new paclitaxel formulation (ART207), in Cancer Stem Cells (CSCs) and Bulk of Tumor Cells from patient-derived cell lines of ovarian, breast colon, pancreas, and lung cancer origin., Romolus Therapeutics08/2023 - 07/2024
Extramural, Improving AAV delivery for immunotherapy, Vesselon01/2022 - 12/2023
Intramural, Ultrasound targeted microbubble destruction for anticancer gene delivery., UMMC Intramural grant01/2021 - 12/2022
Intramural, Sensitizing Effects of Benzyl Isothiocyanate (BITC) on standard treatment for Head and Neck Cancer, CCTS UM/UMMC Preclinical/Translational Unit Award06/2020 - 06/2021
Extramural, Gene therapy is a new approach to treating prostate cancer (PC)., Brown Foundation01/2020 - 12/2022
Extramural, Standard Chemotherapy versus Cancer Stem Cell Assay Directed Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer. NCT0394928301/2019 - 12/2024
Extramural, Standard chemotherapy versus chemotherapy chosen by cancer stem cell chemosensitivity testing in the management of patients with recurrent Glioblastoma Multiforme (GBM).
NCT03632135
01/2017 - 12/2023
Extramural, Preclinical study on a new paclitaxel formulation (ART207), in Cancer Stem Cells (CSCs) and Bulk of Tumor Cells from patient-derived cell lines of ovarian, breast colon, pancreas, and lung cancer origin., Romolus Therapeutics01/2017 - 12/2023
Intramural, Ultrasound targeted microbubble destruction for anticancer gene delivery, UMMC Intramural Grant01/2016 - 12/2017
Extramural, Chemotherapy resistance and sensitivity testing in lung tumors., CTSA MARSHALL/UK12/2012 - 01/2014
Intramural, Chemotherapy resistance and sensitivity testing in tumors of the central nervous system, Dept Neuroscience Marshall University12/2012 - 01/2014
Extramural, Identifying the Role of P53 and PRB Regulated Protein RGS16 in Osteosarcoma Proliferation and Chemoresistance., NASA07/2012 - 06/2013
Intramural, Chemotherapy resistance and sensitivity testing in tumors of the central nervous system, Marshall Univeristy Translational Award07/2012 - 06/2014
Extramural, WV Cancer Genomics Network07/2012 - 06/2017
Extramural, Characterization of HUS1B: a novel player in the p53/pRb tumor suppressor pathways, NASA07/2011 - 06/2012
Extramural, Chemosensitization of Non-Small Lung Cancer Stem Cells with Isothiocyanates., NASA07/2011 - 06/2012
Extramural, Exploring BITC Ability to Enhance Chemosensitivity and Reduce the Metastatic Potential of Head and Neck Cancer Cells., NASA07/2011 - 06/2012
Extramural, Dry beans and colon cancer stem-like cells, from mechanisms to therapy, Northern Bean Growers Association03/2010 - 03/2011
Extramural, Ultrasound-guided gene delivery in pancreatic cancer., NIH08/2009 - 07/2013
Extramural, Ultrasound-guided site-specific gene delivery in prostate cancer, NIH01/2009 - 03/2013
Intramural, Microgravity sensitization to chemotherapy of multi-drug resistant cancer cells, CDDC01/2006 - 12/2008
Extramural, Ultrasound enhancement of viral-mediated gene transfer following systemic administration, WW Smith Foundation01/2004 - 12/2006
Extramural, pRb2/p130 from the mechanism to therapy., NIH01/2003 - 12/2008
Extramural, Role of the RB Family in JC virus-induced glioblastomas., NIH01/2002 - 12/2006

Publications

Letter

Cortese A, Tomeo M, Borri A, Claudio PP, New strategy treatment by epi-mucosa fixation and autologous platelet-rich fibrin in medical related osteonecrosis of the jaws. Minerva stomatologica, 2019 Oct;68(5):274-2752019
Cortese A, Amato M, Pantaleo G, Claudio PP, A Patient With a Rare Single Mandibular Localization of Non-Hodgkin B-Cell Lymphoma: Early Differential Diagnosis With Dental Lesions. The Journal of craniofacial surgery, 2015 Jun;26(4):e365-62015

Randomized Controlled Trial

Ranjan T, Sengupta S, Glantz MJ, Green RM, Yu A, Aregawi D, Chaudhary R, Chen R, Zuccarello M, Lu-Emerson C, Moulding HD, Belman N, Glass J, Mammoser A, Anderson M, Valluri J, Marko N, Schroeder J, Jubelirer S, Chow F, Claudio PP, Alberico AM, Lirette ST, Denning KL, Howard CM, Cancer stem cell assay-guided chemotherapy improves survival of patients with recurrent glioblastoma in a randomized trial. Cell reports. Medicine, 2023 May 16;4(5):1010252023

Journal Article

Diana Polania Villanueva, Charles Ingraham, Annamarie Macaluso, Cecilia Vittori, Jean- Jacques Hunter, Monika Rak, Pier Paolo Claudio, Mahomed A. Ibrahim, Luis Del Valle, Francesca Peruzzi, Branko S Jursic, and Krzysztof Reiss. Antiglioblastoma Drug Candidates Targeting Mitochondrial Respiration. Journal Cell Physiology (in press 2025)2025
Herzog TJ, Krivak TC, Bush S 2nd, Diaz JP, Lentz S, Nair N, Zgheib NB, Gunderson-Jackson C, Barve A, Denning KL, Lirette ST, Howard CM, Valluri J, Claudio PP, ChemoID-guided therapy improves objective response rate in recurrent platinum-resistant ovarian cancer randomized clinical trial. NPJ precision oncology, 2025 Mar 25;9(1):862025
Sitta J, De Carlo F, Kirven I, Tackett JH, Penfornis P, Dobbins GC, Barbier M, Del Valle L, Larsen CT, Schutt EG, Li R, Howard CM, Claudio PP, Microbubble-Protected Oncolytic Virotherapy Targeted by Sonoporation Induces Tumor Necrosis and T-Lymphocyte Infiltration in Humanized Mice Bearing Triple-Negative Breast Cancer. International journal of molecular sciences, 2024 Dec 21;25(24)2024
Bizzoca ME, Caponio VCA, Lo Muzio L, Claudio PP, Cortese A, Methods for Overcoming Chemoresistance in Head and Neck Squamous Cell Carcinoma: Keeping the Focus on Cancer Stem Cells, a Systematic Review. Cancers, 2024 Aug 29;16(17)2024
Spirito F, Claudio PP, Howard CM, Valluri J, Denning KL, Muzio LL, Cortese A. A New and Effective Procedure for Advanced Oral Cancer Therapy: The Potential of a Cancer Stem Cell Assay in Guiding Chemotherapy. Spirito F, Claudio PP, Howard CM, Valluri J, Denning KL, Muzio LL, Cortese A. A New and Effective Procedure for Advanced Oral Cancer Therapy: The Potential of a Cancer Stem Cell Assay in Guiding Chemotherapy. Transl Med UniSa. 2023 Dec 8;25(1):16-27. doi: 10.37825/2239-9747.1042. PMID: 381435092023
Isahia A. Edwards, Flavia De Carlo, Juliana Sitta, William Varner, Candace M. Howard, Pier Paolo Claudio. Ultrasound Enhanced Targeted Therapy in Breast Cancer. Isahia A. Edwards, Flavia De Carlo, Juliana Sitta, William Varner, Candace M. Howard, Pier Paolo Claudio. Ultrasound Enhanced Targeted Therapy in Breast Cancer. Int. J. Mol. Sci. 2023, 24(6), 5474; PMID: 369825482023
Cortese A, Spirito F, Claudio PP, Lo Muzio L, Ruggiero A, Gargiulo M, Mandibular Reconstruction after Resection of Ameloblastoma by Custom-Made CAD/CAM Mandibular Titanium Prosthesis: Two Case Reports, Finite Element Analysis and Discussion of the Technique. Dentistry journal, 2023 Apr 20;11(4)2023
Singh S, De Carlo F, Ibrahim MA, Penfornis P, Mouton AJ, Tripathi SK, Agarwal AK, Eastham L, Pasco DS, Balachandran P, Claudio PP, The Oligostilbene Gnetin H Is a Novel Glycolysis Inhibitor That Regulates Thioredoxin Interacting Protein Expression and Synergizes with OXPHOS Inhibitor in Cancer Cells. International journal of molecular sciences, 2023 Apr 23;24(9)2023
Edwards IA, De Carlo F, Sitta J, Varner W, Howard CM, Claudio PP, Enhancing Targeted Therapy in Breast Cancer by Ultrasound-Responsive Nanocarriers. International journal of molecular sciences, 2023 Mar 13;24(6)2023
Lawrence LM, Salary RR, Miller V, Valluri A, Denning KL, Case-Perry S, Abdelgaber K, Smith S, Claudio PP, Day JB, Osteoregenerative Potential of 3D-Printed Poly ε-Caprolactone Tissue Scaffolds In Vitro Using Minimally Manipulative Expansion of Primary Human Bone Marrow Stem Cells. International journal of molecular sciences, 2023 Mar 3;24(5)2023
Khan MIH, Mahdi F, Penfornis P, Akins NS, Hossain MI, Kim SJ, Sulochana SP, Adam AT, Tran TD, Tan C, Paolo Claudio P, Paris JJ, Le HV, Synthesis and biological evaluation of tert-butyl ester and ethyl ester prodrugs of L-γ-methyleneglutamic acid amides for cancer. Bioorganic & medicinal chemistry, 2023 Jan 15;78:1171372023
Cortese, S. Catalano, C.M. Howard, P.P. Claudio. New minimally invasive intraoral procedure for condylar fractures: clinical case and considerations on current techniques. Cortese, S. Catalano, C.M. Howard, P.P. Claudio. New minimally invasive intraoral procedure for condylar fractures: clinical case and considerations on current techniques. Journal of Maxillofacial Surgery, 2022 May 1;33(3):e245-e247. doi: 10.1097/SCS.0000000000008028. PMID: 344061542022
Cortese A, Catalano S, Rauso R, Claudio PP. Condylar Fractures: Multistep Surgical Planning by Mini-Invasive Approach, Patient Series. Cortese A, Catalano S, Rauso R, Claudio PP. Condylar Fractures: Multistep Surgical Planning by Mini-Invasive Approach, Patient Series. J Craniofac Surg. 2022 Mar 11. doi: 10.1097/SCS.0000000000008643. Online ahead of print. PMID: 352758572022
Sitta J, Claudio PP, Howard CM, Virus-Based Immuno-Oncology Models. Biomedicines, 2022 Jun 18;10(6)2022
Cortese A, Catalano S, Giunta AAM, Borri A, Panetta D, Claudio PP, Lip Reconstruction by Double Layer and Double Flap New Combination Technique: A Case Series. Dentistry journal, 2022 Jan 27;10(2)2022
Haider S, Penfornis P, Claudio PP, McChesney JD, Chittiboyina AG, Balancing the efficacy vs. the toxicity of promiscuous natural products: Paclitaxel-based acid-labile lipophilic prodrugs as promising chemotherapeutics. European journal of medicinal chemistry, 2022 Jan 5;227:1138912022
Candace M. Howard, Stephen Bush II, Nadim Bou Zgheib, Antonio Cortese, Antonio Mollo, Jagan Valluri, and Pier Paolo Claudio. Cancer Stem Cell Assay for the treatment of Recurrent Ovarian Cancer. Candace M. Howard, Stephen Bush II, Nadim Bou Zgheib, Antonio Cortese, Antonio Mollo, Jagan Valluri, and Pier Paolo Claudio. Cancer Stem Cell Assay for the treatment of Recurrent Ovarian Cancer. J Stem Cell Res Dev Ther 2021, 7: 076. DOI: 10.24966/SRDT-2060/1000762021
Cortese A, Casarella A, Howard CM, Claudio PP, Epi-Mucosa Fixation and Autologous Platelet-Rich Fibrin Treatment in Medication-Related Osteonecrosis of the Jaw. Dentistry journal, 2021 Apr 30;9(5)2021
Cortese A, Borri A, Bergaminelli M, Bergaminelli F, Claudio PP, Condylar Neck and Sub-Condylar Fractures: Surgical Consideration and Evolution of the Technique with Short Follow-Up on Five Cases. Dentistry journal, 2020 Nov 3;8(4)2020
Howard CM, Zgheib NB, Bush S 2nd, DeEulis T, Cortese A, Mollo A, Lirette ST, Denning K, Valluri J, Claudio PP, Clinical relevance of cancer stem cell chemotherapeutic assay for recurrent ovarian cancer. Translational oncology, 2020 Dec;13(12):1008602020
Lawrence LM, Russell R, Denning CE, Zgheib NB, Salisbury T, Lirette ST, Valluri J, Claudio PP, Denning KL, Expression of poly-ADP-ribose polymerase (PARP) in endometrial adenocarcinoma: Prognostic potential. Pathology, research and practice, 2020 Jun;216(6):1529652020
Ranjan T, Howard CM, Yu A, Xu L, Aziz K, Jho D, Leonardo J, Hameed MA, Karlovits SM, Wegner RE, Fuhrer R, Lirette ST, Denning KL, Valluri J, Claudio PP, Cancer Stem Cell Chemotherapeutics Assay for Prospective Treatment of Recurrent Glioblastoma and Progressive Anaplastic Glioma: A Single-Institution Case Series. Translational oncology, 2020 Apr;13(4):1007552020
Sakiyama MJ, Espinoza I, Reddy A, de Carlo F, Kumar A, Levenson AS, Bae S, Zhou X, Claudio PP, Lewin J, Manucha V, Pound CR, Vijayakumar S, Gomez CR, Race-associated expression of MHC class I polypeptide-related sequence A (MICA) in prostate cancer. Experimental and molecular pathology, 2019 Jun;108:173-1822019
Lawrence LM, Cottrill A, Valluri A, Marenzi G, Denning KL, Valluri J, Claudio PP, Day JB, Minimally Manipulative Method for the Expansion of Human Bone Marrow Mesenchymal Stem Cells to Treat Osseous Defects. International journal of molecular sciences, 2019 Jan 31;20(3)2019
De Carlo F, Thomas L, Brooke B, Varney ET, Nande R, Boskovic O, Marshall GD, Claudio PP, Howard CM, Microbubble-mediated delivery of human adenoviruses does not elicit innate and adaptive immunity response in an immunocompetent mouse model of prostate cancer. Journal of translational medicine, 2019 Jan 11;17(1):192019
Carlino F, Claudio PP, Tomeo M, Cortese A, Mandibular bi-directional distraction osteogenesis: A technique to manage both transverse and sagittal mandibular diameters via a lingual tooth-borne acrylic plate and double-hinge bone anchorage. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2019 Oct;47(10):1521-15292019
Cortese A, Pantaleo G, Caggiano M, Gargiulo M, Claudio PP, Amato M, Lip reconstruction by new split cheek flap. Minerva stomatologica, 2018 Jun;67(3):139-1402018
Cortese A, Pantaleo G, Caggiano M, Amato M, Claudio PP, New technique for large mandibular and surrounding soft tissue reconstruction that uses an intraoral three-dimensional distractor for one step transport disc distraction osteogenesis. Minerva stomatologica, 2018 Aug;67(4):179-1812018
Timothy G. DeEulis, Candace M. Howard, Jagan Valluri, and Pier Paolo Claudio. Efficacy of ChemoID guided drug selection for palliative chemotherapy in advanced recurrent high-grade ovarian adenocarcinoma: Case Study. Translational Medicine Reports, vol 1: 6701, 70-75, 2017. Timothy G. DeEulis, Candace M. Howard, Jagan Valluri, and Pier Paolo Claudio. Efficacy of ChemoID guided drug selection for palliative chemotherapy in advanced recurrent high-grade ovarian adenocarcinoma: Case Study. Translational Medicine Reports, vol 1: 6701, 70-75, 2017.2017
Cortese A, Pantaleo G, Amato M, Howard CM, Pedicini L, Claudio PP, Platelet-Rich Fibrin (PRF) in Implants Dentistry in Combination with New Bone Regenerative Flapless Technique: Evolution of the Technique and Final Results. Open medicine (Warsaw, Poland), 2017 Jan;12:24-322017
Howard CM, Valluri J, Alberico A, Julien T, Mazagri R, Marsh R, Alastair H, Cortese A, Griswold M, Wang W, Denning K, Brown L, Claudio PP, Analysis of Chemopredictive Assay for Targeting Cancer Stem Cells in Glioblastoma Patients. Translational oncology, 2017 Apr;10(2):241-2542017
Greco A, Albanese S, Auletta L, DE Carlo F, Salvatore M, Howard CM, Claudio PP, Advances in molecular preclinical therapy mediated by imaging. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2017 Mar;61(1):76-942017
Cortese A, Pantaleo G, Borri A, Amato M, Claudio PP, Necrotizing odontogenic fasciitis of head and neck extending to anterior mediastinum in elderly patients: innovative treatment with a review of the literature. Aging clinical and experimental research, 2017 Feb;29(Suppl 1):159-1652017
Carlino F, Villani GP, Berti A, Pantaleo G, Cortese A, Claudio PP, Osteodistraction With Dental Implant-Borne Devices for Bone Regeneration in Atrophied Premaxilla. The Journal of craniofacial surgery, 2016 Nov;27(8):e776-e7792016
Cortese A, D'Alessio G, Brongo S, Gargiulo M, Claudio PP, Management of Zygomatic Fractures in Young Patients: Technical Modifications for Aesthetic and Functional Results. The Journal of craniofacial surgery, 2016 Nov;27(8):2073-20772016
Carlino F, Pantaleo G, Ciuffolo F, Claudio PP, Cortese A, New Technique for Mandibular Symphyseal Distraction by a Double-Level Anchorage and Fixation System: Advantages and Results. The Journal of craniofacial surgery, 2016 Sep;27(6):1469-752016
Cortese A, D'Alessio G, Brongo S, Amato M, Sarno MR, Claudio PP, New Techniques in Relation to New Concepts of the Aesthetic of the Face: Technical Considerations and Aesthetic Evaluation. The Journal of craniofacial surgery, 2016 Oct;27(7):e693-e6952016
Cortese A, Pantaleo G, Amato M, Claudio PP, Ridge Expansion by Flapless Split Crest and Immediate Implant Placement: Evolution of the Technique. The Journal of craniofacial surgery, 2016 Mar;27(2):e123-82016
Carper MB, Claudio PP, Clinical potential of gene mutations in lung cancer. Clinical and translational medicine, 2015 Dec;4(1):332015
Hampton KK, Stewart R, Napier D, Claudio PP, Craven RJ, PGRMC1 Elevation in Multiple Cancers and Essential Role in Stem Cell Survival. Advances in lung cancer (Irvine), 2015 Sep;4(3):37-512015
Koc EC, Haciosmanoglu E, Claudio PP, Wolf A, Califano L, Friscia M, Cortese A, Koc H, Impaired mitochondrial protein synthesis in head and neck squamous cell carcinoma. Mitochondrion, 2015 Sep;24:113-212015
Cortese A, Pantaleo G, Amato M, Claudio PP, Chin Wing Osteotomy for Bilateral Goldenhar Syndrome Treated by "Chin Wing Mentoplasty": Aesthetic, Functional, and Histological Considerations. The Journal of craniofacial surgery, 2015 Jul;26(5):1628-302015
Morra F, Luise C, Merolla F, Poser I, Visconti R, Ilardi G, Paladino S, Inuzuka H, Guggino G, Monaco R, Colecchia D, Monaco G, Cerrato A, Chiariello M, Denning K, Claudio PP, Staibano S, Celetti A, FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC. Oncotarget, 2015 May 20;6(14):12697-7092015
Carper MB, Denvir J, Boskovic G, Primerano DA, Claudio PP, RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells. Genes & cancer, 2014 Nov;5(11-12):420-352014
Cortese A, Savastano G, Amato M, Pantaleo G, Claudio PP, Intraoral epimucosal fixation for reducible maxillary fractures of the jaws; surgical considerations in comparison to current techniques. The Journal of craniofacial surgery, 2014 Nov;25(6):2184-72014
Cortese A, Savastano G, Amato M, Cantone A, Boschetti C, Claudio PP, New palatal distraction device by both bone-borne and tooth-borne force application in a paramedian bone anchorage site: surgical and occlusal considerations on clinical cases. The Journal of craniofacial surgery, 2014 Mar;25(2):589-952014
Cortese A, Savastano M, Cantone A, Claudio PP, A new palatal distractor device for bodily movement of maxillary bones by rigid self-locking miniplates and screws system. The Journal of craniofacial surgery, 2013 Jul;24(4):1341-62013
Bagashev A, Fan S, Mukerjee R, Claudio PP, Chabrashvili T, Leng RP, Benchimol S, Sawaya BE, Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein. Cell cycle (Georgetown, Tex.), 2013 May 15;12(10):1569-772013
Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP, Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer. Current gene therapy, 2013 Jun 1;13(3):163-742013
Cortese A, Savastano M, Savastano G, Claudio PP, One-step transversal palatal distraction and maxillary repositioning: technical considerations, advantages, and long-term stability. The Journal of craniofacial surgery, 2011 Sep;22(5):1714-92011
Dash R, Azab B, Shen XN, Sokhi UK, Sarkar S, Su ZZ, Wang XY, Claudio PP, Dent P, Dmitriev IP, Curiel DT, Grant S, Sarkar D, Fisher PB, Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic. Discovery medicine.., 2011 Jan;11(56):46-562011
Gossman MS, Das IJ, Sharma SC, Lopez JP, Howard CM, Claudio P, A novel phantom model for mouse tumor dose assessment under MV beams. Health physics, 2011 Dec;101(6):746-532011
Mukerjee R, Claudio PP, Chang JR, Del Valle L, Sawaya BE, Transcriptional regulation of HIV-1 gene expression by p53. Cell cycle (Georgetown, Tex.), 2010 Nov 15;9(22):4569-782010
Aimola P, Desiderio V, Graziano A, Claudio PP, Stem cells in cancer therapy: From their role in pathogenesis to their use as therapeutic agents. Drug news & perspectives, 2010 Apr;23(3):175-832010
Kelly SE, Di Benedetto A, Greco A, Howard CM, Sollars VE, Primerano DA, Valluri JV, Claudio PP, Rapid selection and proliferation of CD133+ cells from cancer cell lines: chemotherapeutic implications. PloS one, 2010 Apr 8;5(4):e100352010
Cortese A, Savastano M, Savastano G, Papa F, Howard CM, Claudio PP, Maxillary constriction treated by a new palatal distractor device: surgical and occlusal evaluations of 10 patients. The Journal of craniofacial surgery, 2010 Mar;21(2):339-432010
Greco A, Di Benedetto A, Howard CM, Kelly S, Nande R, Dementieva Y, Miranda M, Brunetti A, Salvatore M, Claudio L, Sarkar D, Dent P, Curiel DT, Fisher PB, Claudio PP, Eradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach. Molecular therapy : the journal of the American Society of Gene Therapy, 2010 Feb;18(2):295-3062010
Vogiatzi P, Cassone M, Claudio L, Claudio PP, Targeted therapy for advanced prostate cancer: Looking through new lenses. Drug news & perspectives, 2009 Dec;22(10):593-6012009
Papa F, Cortese A, Sagliocco R, Farella M, Banzi C, Maltarello MC, Pellegrini C, D'Agostino E, Aimola P, Claudio PP, Outcome of 47 consecutive sinus lift operations using aragonitic calcium carbonate associated with autologous platelet-rich plasma: clinical, histologic, and histomorphometrical evaluations. The Journal of craniofacial surgery, 2009 Nov;20(6):2067-742009
Sammartino G, Tia M, Gentile E, Marenzi G, Claudio PP, Platelet-rich plasma and resorbable membrane for prevention of periodontal defects after deeply impacted lower third molar extraction. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009 Nov;67(11):2369-732009
Vattemi E, Claudio PP, The feasibility of gene therapy in the treatment of head and neck cancer. Head & neck oncology, 2009 Jan 12;1:32009
Sammartino G, Marenzi G, Howard CM, Minimo C, Trosino O, Califano L, Claudio PP, Chondrosarcoma of the jaw: a closer look at its management. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008 Nov;66(11):2349-552008
Vogiatzi P, Aimola P, Scarano MI, Claudio PP, Epigenome-derived drugs: recent advances and future perspectives. Drug news & perspectives, 2007 Dec;20(10):627-332007
Vattemi E, Claudio PP, Tumor suppressor genes as cancer therapeutics. Drug news & perspectives, 2007 Oct;20(8):511-202007
Abbadessa G, Vogiatzi P, Rimassa L, Claudio PP, Antiangiogenic drugs currently used for colorectal cancer: what other pathways can we target to prolong responses? Drug news & perspectives, 2007 Jun;20(5):307-132007
De Falco G, Leucci E, Lenze D, Piccaluga PP, Claudio PP, Onnis A, Cerino G, Nyagol J, Mwanda W, Bellan C, Hummel M, Pileri S, Tosi P, Stein H, Giordano A, Leoncini L, Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors. Blood, 2007 Aug 15;110(4):1301-72007
Caracciolo V, Reiss K, Crozier-Fitzgerald C, De Pascali F, Macaluso M, Khalili K, Giordano A, Claudio PP, Interplay between the retinoblastoma related pRb2/p130 and E2F-4 and -5 in relation to JCV-TAg. Journal of cellular physiology, 2007 Jul;212(1):96-1042007
Bagella L, Sun A, Tonini T, Abbadessa G, Cottone G, Paggi MG, De Luca A, Claudio PP, Giordano A, A small molecule based on the pRb2/p130 spacer domain leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo. Oncogene, 2007 Mar 22;26(13):1829-392007
Mattioli E, Vogiatzi P, Sun A, Abbadessa G, Angeloni G, D'Ugo D, Trani D, Gaughan JP, Vecchio FM, Cevenini G, Persiani R, Giordano A, Claudio PP, Immunohistochemical analysis of pRb2/p130, VEGF, EZH2, p53, p16(INK4A), p27(KIP1), p21(WAF1), Ki-67 expression patterns in gastric cancer. Journal of cellular physiology, 2007 Jan;210(1):183-912007
Quinti I, Soresina A, Spadaro G, Martino S, Donnanno S, Agostini C, Claudio P, Franco D, Maria Pesce A, Borghese F, Guerra A, Rondelli R, Plebani A, Italian Primary Immunodeficiency Network, Long-term follow-up and outcome of a large cohort of patients with common variable immunodeficiency. Journal of clinical immunology, 2007 May;27(3):308-162007
Vogiatzi P, Cassone M, Claudio PP, Personalizing gene therapy in gastric cancer. Drug news & perspectives, 2006 Nov;19(9):533-402006
Vogiatzi P, Cassone M, Abbadessa G, Claudio PP, The limitless role of p53 in cell cycle machinery: good news or bad news? Cancer biology & therapy, 2006 Sep;5(9):1090-32006
Genovese C, Trani D, Caputi M, Claudio PP, Cell cycle control and beyond: emerging roles for the retinoblastoma gene family. Oncogene, 2006 Aug 28;25(38):5201-92006
Howard CM, Forsberg F, Minimo C, Liu JB, Merton DA, Claudio PP, Ultrasound guided site specific gene delivery system using adenoviral vectors and commercial ultrasound contrast agents. Journal of cellular physiology, 2006 Nov;209(2):413-212006
Claudio PP, Cui J, Ghafouri M, Mariano C, White MK, Safak M, Sheffield JB, Giordano A, Khalili K, Amini S, Sawaya BE, Cdk9 phosphorylates p53 on serine 392 independently of CKII. Journal of cellular physiology, 2006 Sep;208(3):602-122006
Vogiatzi P, De Falco G, Claudio PP, Giordano A, How does the human RUNX3 gene induce apoptosis in gastric cancer? Latest data, reflections and reactions. Cancer biology & therapy, 2006 Apr;5(4):371-42006
Merola E, Mattioli E, Minimo C, Zuo W, Rabitti C, Cicala M, Caviglia R, Pollice L, Gabbrielli A, Giordano A, Claudio PP, Immunohistochemical evaluation of pRb2/p130, VEGF, EZH2, p53, p16, p21waf-1, p27, and PCNA in Barrett's esophagus. Journal of cellular physiology, 2006 May;207(2):512-92006
Giacinti L, Claudio PP, Lopez M, Giordano A, Epigenetic information and estrogen receptor alpha expression in breast cancer. The oncologist, 2006 Jan;11(1):1-82006
Sanseverino F, Santopietro R, Torricelli M, D'Andrilli G, Russo G, Cevenini G, Bovicelli A, Leoncini L, Scambia G, Petraglia F, Claudio PP, Giordano A, pRb2/p130 and VEGF expression in endometrial carcinoma in relation to angiogenesis and histopathologic tumor grade. Cancer biology & therapy, 2006 Jan;5(1):84-82006
Merola E, Claudio PP, Giordano A, p53 and the malignant progression of Barrett's esophagus. Journal of cellular physiology, 2006 Mar;206(3):574-72006
Papa F, Cortese A, Maltarello MC, Sagliocco R, Felice P, Claudio PP, Outcome of 50 consecutive sinus lift operations. The British journal of oral & maxillofacial surgery, 2005 Aug;43(4):309-132005
Russo G, Zamparelli A, Howard CM, Minimo C, Bellan C, Carillo G, Califano L, Leoncini L, Giordano A, Claudio PP, Expression of cell cycle-regulated proteins pRB2/p130, p107, E2F4, p27, and pCNA in salivary gland tumors: prognostic and diagnostic implications. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005 May 1;11(9):3265-732005
Claudio PP, Russo G, Kumar CA, Minimo C, Farina A, Tutton S, Nuzzo G, Giuliante F, Angeloni G, Maria V, Vecchio FM, Campli CD, Giordano A, pRb2/p130, vascular endothelial growth factor, p27(KIP1), and proliferating cell nuclear antigen expression in hepatocellular carcinoma: their clinical significance. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004 May 15;10(10):3509-172004
Tonini T, Bagella L, D'Andrilli G, Claudio PP, Giordano A, Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A. Oncogene, 2004 Jun 17;23(28):4930-72004
Russo G, Claudio PP, Fu Y, Stiegler P, Yu Z, Macaluso M, Giordano A, pRB2/p130 target genes in non-small lung cancer cells identified by microarray analysis. Oncogene, 2003 Oct 9;22(44):6959-692003
Tonini T, Rossi F, Claudio PP, Molecular basis of angiogenesis and cancer. Oncogene, 2003 Sep 29;22(42):6549-562003
De Falco G, Bellan C, Lazzi S, Claudio P, La Sala D, Cinti C, Tosi P, Giordano A, Leoncini L, Interaction between HIV-1 Tat and pRb2/p130: a possible mechanism in the pathogenesis of AIDS-related neoplasms. Oncogene, 2003 Sep 18;22(40):6214-92003
Condorelli G, Morisco C, Latronico MV, Claudio PP, Dent P, Tsichlis P, Condorelli G, Frati G, Drusco A, Croce CM, Napoli C, TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002 Nov;16(13):1732-72002
Claudio PP, Tonini T, Giordano A, The retinoblastoma family: twins or distant cousins? Genome biology, 2002 Aug 28;3(9):reviews30122002
Lazzi S, Bellan C, De Falco G, Cinti C, Ferrari F, Nyongo A, Claudio PP, Tosi GM, Vatti R, Gloghini A, Carbone A, Giordano A, Leoncini L, Tosi P, Expression of RB2/p130 tumor-suppressor gene in AIDS-related non-Hodgkin's lymphomas: implications for disease pathogenesis. Human pathology, 2002 Jul;33(7):723-312002
Pucci B, Claudio PP, Masciullo V, Bellincampi L, Terrinoni A, Khalili K, Melino G, Giordano A, pRb2/p130 promotes radiation-induced cell death in the glioblastoma cell line HJC12 by p73 upregulation and Bcl-2 downregulation. Oncogene, 2002 Aug 29;21(38):5897-9052002
Tonini T, Hillson C, Claudio PP, Interview with the retinoblastoma family members: do they help each other? Journal of cellular physiology, 2002 Aug;192(2):138-502002
Claudio PP, Zamparelli A, Garcia FU, Claudio L, Ammirati G, Farina A, Bovicelli A, Russo G, Giordano GG, McGinnis DE, Giordano A, Cardi G, Expression of cell-cycle-regulated proteins pRb2/p130, p107, p27(kip1), p53, mdm-2, and Ki-67 (MIB-1) in prostatic gland adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002 Jun;8(6):1808-152002
Zini N, Trimarchi C, Claudio PP, Stiegler P, Marinelli F, Maltarello MC, La Sala D, De Falco G, Russo G, Ammirati G, Maraldi NM, Giordano A, Cinti C, pRb2/p130 and p107 control cell growth by multiple strategies and in association with different compartments within the nucleus. Journal of cellular physiology, 2001 Oct;189(1):34-442001
Galderisi U, Melone MA, Jori FP, Piegari E, Di Bernardo G, Cipollaro M, Cascino A, Peluso G, Claudio PP, Giordano A, pRb2/p130 gene overexpression induces astrocyte differentiation. Molecular and cellular neurosciences, 2001 Mar;17(3):415-252001
Claudio PP, Cinti C, Giordano A, Application of the primer in situ DNA synthesis (PRINS) technique to titer recombinant virus and evaluation of the efficiency of viral transduction. Analytical biochemistry, 2001 Apr 1;291(1):96-1012001
Claudio PP, Stiegler P, Howard CM, Bellan C, Minimo C, Tosi GM, Rak J, Kovatich A, De Fazio P, Micheli P, Caputi M, Leoncini L, Kerbel R, Giordano GG, Giordano A, RB2/p130 gene-enhanced expression down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in vivo. Cancer research, 2001 Jan 15;61(2):462-82001
Cinti C, Claudio PP, Luca AD, Cuccurese M, Howard CM, D'Esposito M, Paggi MG, Sala DL, Azzoni L, Halazonetis TD, Giordano A, Maraldi NM, A serine 37 mutation associated with two missense mutations at highly conserved regions of p53 affect pro-apoptotic genes expression in a T-lymphoblastoid drug resistant cell line. Oncogene, 2000 Oct 19;19(44):5098-1052000
Perrotti D, Iervolino A, Cesi V, Cirinná M, Lombardini S, Grassilli E, Bonatti S, Claudio PP, Calabretta B, BCR-ABL prevents c-jun-mediated and proteasome-dependent FUS (TLS) proteolysis through a protein kinase CbetaII-dependent pathway. Molecular and cellular biology, 2000 Aug;20(16):6159-692000
Howard CM, Claudio PP, De Luca A, Stiegler P, Jori FP, Safdar NM, Caputi M, Khalili K, Giordano A, Inducible pRb2/p130 expression and growth-suppressive mechanisms: evidence of a pRb2/p130, p27Kip1, and cyclin E negative feedback regulatory loop. Cancer research, 2000 May 15;60(10):2737-442000
Claudio PP, Caputi M, Giordano A, The RB2/p130 gene: the latest weapon in the war against lung cancer? Clinical cancer research : an official journal of the American Association for Cancer Research, 2000 Mar;6(3):754-642000
Cinti C, Leoncini L, Nyongo A, Ferrari F, Lazzi S, Bellan C, Vatti R, Zamparelli A, Cevenini G, Tosi GM, Claudio PP, Maraldi NM, Tosi P, Giordano A, Genetic alterations of the retinoblastoma-related gene RB2/p130 identify different pathogenetic mechanisms in and among Burkitt's lymphoma subtypes. The American journal of pathology, 2000 Mar;156(3):751-602000
Cinti C, Claudio PP, Howard CM, Neri LM, Fu Y, Leoncini L, Tosi GM, Maraldi NM, Giordano A, Genetic alterations disrupting the nuclear localization of the retinoblastoma-related gene RB2/p130 in human tumor cell lines and primary tumors. Cancer research, 2000 Jan 15;60(2):383-92000
Claudio PP, Howard CM, Pacilio C, Cinti C, Romano G, Minimo C, Maraldi NM, Minna JD, Gelbert L, Leoncini L, Tosi GM, Hicheli P, Caputi M, Giordano GG, Giordano A, Mutations in the retinoblastoma-related gene RB2/p130 in lung tumors and suppression of tumor growth in vivo by retrovirus-mediated gene transfer. Cancer research, 2000 Jan 15;60(2):372-822000
De Falco G, Bagella L, Claudio PP, De Luca A, Fu Y, Calabretta B, Sala A, Giordano A, Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation. Oncogene, 2000 Jan 20;19(3):373-92000
Claudio PP, Howard CM, Fu Y, Cinti C, Califano L, Micheli P, Mercer EW, Caputi M, Giordano A, Mutations in the retinoblastoma-related gene RB2/p130 in primary nasopharyngeal carcinoma. Cancer research, 2000 Jan 1;60(1):8-122000
Leoncini L, Bellan C, Cossu A, Claudio PP, Lazzi S, Cinti C, Cevenini G, Megha T, Laurini L, Luzi P, Orcioni GF, Piccioli M, Pileri S, Giardino C, Tosi P, Giordano A, Retinoblastoma-related p107 and pRb2/p130 proteins in malignant lymphomas: distinct mechanisms of cell growth control. Clinical cancer research : an official journal of the American Association for Cancer Research, 1999 Dec;5(12):4065-721999
Claudio PP, Fratta L, Farina F, Howard CM, Stassi G, Numata S, Pacilio C, Davis A, Lavitrano M, Volpe M, Wilson JM, Trimarco B, Giordano A, Condorelli G, Adenoviral RB2/p130 gene transfer inhibits smooth muscle cell proliferation and prevents restenosis after angioplasty. Circulation research, 1999 Nov 26;85(11):1032-91999
Numata S, Claudio PP, Dean C, Giordano A, Croce CM, Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product. Cancer research, 1999 Aug 1;59(15):3741-71999
Cortese A., D’Alessio G., Brongo S., Gargiulo M., Claudio P.P. Management of zygomatic fractures in young patients: Technical modifications for aesthetic and functional results. Cortese A., D’Alessio G., Brongo S., Gargiulo M., Claudio P.P. Management of zygomatic fractures in young patients: Technical modifications for aesthetic and functional results. J. Craniofacial Surgery 2016; Nov 27 (8): 2073-2077. PMID 28005755
Cortese A, D’Alessio G, Brongo S, Amato M, Sarno MR, Claudio PP. New Techniques in Relation to New Concepts of the Aesthetic of the Face: Technical Considerations and Aesthetic Evaluation. Cortese A, D’Alessio G, Brongo S, Amato M, Sarno MR, Claudio PP. New Techniques in Relation to New Concepts of the Aesthetic of the Face: Technical Considerations and Aesthetic Evaluation. J Craniofac Surg 2016, Oct;27(7):e693-e695. PMID: 27564069
Steve J. Bannister, Amir E. Wahba, Mahesh Kumar Gundluru, Igor Nikoulin, Douglas L. Rodenburg, Michael L. Coen, David A. Lewis, Patrice Penfornis, Pier Paolo Claudio, James D. McChesney. TumorSelect® Technology Enhancing the Safety and Efficacy of Cancer Chemotherapy. Steve J. Bannister, Amir E. Wahba, Mahesh Kumar Gundluru, Igor Nikoulin, Douglas L. Rodenburg, Michael L. Coen, David A. Lewis, Patrice Penfornis, Pier Paolo Claudio, James D. McChesney. TumorSelect® Technology Enhancing the Safety and Efficacy of Cancer Chemotherapy. BMC Cancer. DOI 10.21203/rs.3.rs-701601/v1
Cortese A, Pantaleo G, Amato M, Lawrence L, Mayes V, Brown L, Sarno MR, Valluri J, Claudio PP, A new complementary procedure for patients affected by head and neck cancer: Chemo-predictive assay. International journal of surgery case reports, 2016;26:42-6
Nande R, Howard CM, Claudio PP, Ultrasound-mediated oncolytic virus delivery and uptake for increased therapeutic efficacy: state of art. Oncolytic virotherapy, 2015;4:193-205
Mathis SE, Alberico A, Nande R, Neto W, Lawrence L, McCallister DR, Denvir J, Kimmey GA, Mogul M, Oakley G 3rd, Denning KL, Dougherty T, Valluri JV, Claudio PP, Chemo-predictive assay for targeting cancer stem-like cells in patients affected by brain tumors. PloS one, 2014;9(8):e105710
Wolf MA, Claudio PP, Benzyl isothiocyanate inhibits HNSCC cell migration and invasion, and sensitizes HNSCC cells to cisplatin. Nutrition and cancer, 2014;66(2):285-94
De Carlo F, Witte TR, Hardman WE, Claudio PP, Omega-3 eicosapentaenoic acid decreases CD133 colon cancer stem-like cell marker expression while increasing sensitivity to chemotherapy. PloS one, 2013;8(7):e69760
Nande R, Di Benedetto A, Aimola P, De Carlo F, Carper M, Claudio CD, Denvir J, Valluri J, Duncan GC, Claudio PP, Targeting a newly established spontaneous feline fibrosarcoma cell line by gene transfer. PloS one, 2012;7(5):e37743
Aimola P, Carmignani M, Volpe AR, Di Benedetto A, Claudio L, Waalkes MP, van Bokhoven A, Tokar EJ, Claudio PP, Cadmium induces p53-dependent apoptosis in human prostate epithelial cells. PloS one, 2012;7(3):e33647
Greco A, Mancini M, Gargiulo S, Gramanzini M, Claudio PP, Brunetti A, Salvatore M, Ultrasound biomicroscopy in small animal research: applications in molecular and preclinical imaging. Journal of biomedicine & biotechnology, 2012;2012:519238
Pedersini R, Vattemi E, Claudio PP, Adenoviral gene therapy in high-grade malignant glioma. Drug news & perspectives, 2010 Jul-Aug;23(6):368-79
Vattemi E, Claudio PP, Adenoviral gene therapy in head and neck cancer. Drug news & perspectives, 2006 Jul-Aug;19(6):329-37
Tonini T, Claudio PP, Giordano A, Romano G, Retroviral and lentiviral vector titration by the analysis of the activity of viral reverse transcriptase. Methods in molecular biology (Clifton, N.J.), 2004;285:155-7
Tonini T, Claudio PP, Giordano A, Romano G, Determination of functional viral titer by drug-resistance colony assay, expression of green fluorescent protein, and beta-galactoside staining. Methods in molecular biology (Clifton, N.J.), 2004;285:149-53
Tonini T, Claudio PP, Giordano A, Romano G, Transient production of retroviral- and lentiviral-based vectors for the transduction of Mammalian cells. Methods in molecular biology (Clifton, N.J.), 2004;285:141-8
Romano G, Claudio PP, Tonini T, Giordano A, Human immunodeficiency virus type 1 (HIV-1) derived vectors: safety considerations and controversy over therapeutic applications. European journal of dermatology : EJD, 2003 Sep-Oct;13(5):424-9
Claudio PP, Giordano A, Preparation of retroviral vectors for cell-cycle-targeted gene therapy of lung cancer. Methods in molecular medicine, 2003;75:591-605
Papa F, Ferrara S, Felicetta L, Lavorgna G, Matarazzo M, Staibano S, De Rosa G, Troisi S, Claudio PP, Mandibular metastatic hepatocellular carcinoma: report of a case involving severe and uncontrollable hemorrhage. Anticancer research, 2001 May-Jun;21(3C):2121-30
Pagnini U, Pacilio C, Florio S, Crispino A, Claudio PP, Giordano A, Pagnini G, Medroxyprogesterone acetate increases anthracyclines uptake in chronic lymphatic leukemia cells: role of nitric oxide and lipid peroxidation. Anticancer research, 2000 Jan-Feb;20(1A):33-42
Olmi S, Cesana G, Sagutti L, Pagano C, Vittoria G, Croce E, Laparoscopic incisional hernia repair with fibrin glue in select patients. JSLS : Journal of the Society of Laparoendoscopic Surgeons, 2010 Apr-Jun;14(2):240-5
Ranjan T, Yu A, Elhamdani S, Howard CM, Lirette ST, Denning KL, Valluri J, Claudio PP, Treatment of unmethylated MGMT-promoter recurrent glioblastoma with cancer stem cell assay-guided chemotherapy and the impact on patients' healthcare costs. Neuro-oncology advances, 2023 Jan-Dec;5(1):vdad055
Cortese A, Catalano S, Rauso R, Claudio PP, Condylar Fractures: Multistep Surgical Planning by Mini-Invasive Approach, Patient Series. The Journal of craniofacial surgery, 2022 Jul-Aug 01;33(5):e532-e537
Howard CM, Bush S 2nd, Zgheib NB, Lirette ST, Cortese A, Mollo A, Valluri J, Claudio PP, Cancer Stem Cell Assay for the Treatment of Platinum-Resistant Recurrent Ovarian Cancer. HSOA journal of stem cells research, development & therapy, 2021;7(3)
Eastham LL, Howard CM, Balachandran P, Pasco DS, Claudio PP, Eating Green: Shining Light on the Use of Dietary Phytochemicals as a Modern Approach in the Prevention and Treatment of Head and Neck Cancers. Current topics in medicinal chemistry, 2018;18(3):182-191
Florez E, Fatemi A, Claudio PP, Howard CM, Emergence of Radiomics: Novel Methodology Identifying Imaging Biomarkers of Disease in Diagnosis, Response, and Progression. SM journal of clinical and medical imaging, 2018;4(1)
Cortese A, Barbaro R, Troisi D, D'Alessio G, Amato M, Lo Giudice R, Paolo Claudio P, Distraction techniques for face and smile aesthetic preventing ageing decay. Open medicine (Warsaw, Poland), 2016;11(1):433-442
Spirito F, Claudio PP, Howard CM, Valluri J, Denning KL, Muzio LL, Cortese A, A New and Effective Procedure for Advanced Oral Cancer Therapy: The Potential of a Cancer Stem Cell Assay in Guiding Chemotherapy. Translational medicine @ UniSa, 2023;25(1):16-27

Book Chapter

Rounak Nande and Pier Paolo Claudio Ultrasound Contrast Agents in Cancer Therapy. Rounak Nande and Pier Paolo Claudio. (2014) Ultrasound Contrast Agents in Cancer Therapy. In P.P. Claudio & V. Vogiatzi (Eds.), Cutting edge therapies for cancer in the 21st century. Oak Park, IL: Bentham Science Publishers Ltd.2014
Wolf, M.A. and P.P. Claudio Isothiocyanates target carcinogenesis during tumor initiation, promotion, and progression Wolf, M.A. and P.P. Claudio (2012). Isothiocyanates target carcinogenesis during tumor initiation, promotion, and progression/Article. In P.P. Claudio & R.M. Niles (Eds.), Nutrition and Cancer: From Epidemiology to Biology (p79-86). Oak Park, IL: Bentham Science Publishers Ltd.2012
Paraskevi Vogiatzi, Maria Irene Scarano, and Pier Paolo Claudio Epigenetic Targets and Drug Development. In Cancer Epigenetics: Paraskevi Vogiatzi, Maria Irene Scarano, and Pier Paolo Claudio. Chapter 14. Epigenetic Targets and Drug Development. In Cancer Epigenetics: Biomolecular Therapeutics in Human Cancer. John Wiley and Sons Ltd, March 2012, Pages: 436.2012
Claudio P.P. and Vogiatzi P. Distinct roles of the pocket proteins in the control of cell cycle. Claudio P.P. and Vogiatzi P. (2010): Distinct roles of the pocket proteins in the control of cell cycle. In: Signal Transduction: Pathways, Mechanisms, and Diseases. Springer Ed. 353-374.2010
Claudio P.P. and Denning D. Nasopharyngeal carcinoma. In Cancer Research, an encyclopedic reference book. Claudio P.P. and Denning D. (2007): Nasopharyngeal carcinoma. In Cancer Research, an encyclopedic reference book. Springer Ed. 615-618.2007
Alessandro Bovicelli, Pier Paolo Claudio and Antonio Giordano. The multidisciplinary therapeutic approach to gynecological cancer in the new millennium. Molecular Pathology of Gynecological Cancer. Part VII: The multidisciplinary therapeutic approach to gynecological cancer in the new millennium. Chapter 13: The Holistic Approach to Female Cancer Patients. Alessandro Bovicelli, Pier Paolo Claudio and Antonio Giordano. Humana Press.2007
Pier Paolo Claudio, Antonio Giordano Angiogenesis and cancer. Practical Medical Oncology. Pier Paolo Claudio, Antonio Giordano. Angiogenesis and cancer. Practical Medical Oncology. Ed M. Lopez. Second Edition 2005.2005
Tiziana Tonini, Pier Paolo Claudio, Antonio Giordano and Gaetano Romano. Retroviral and lentiviral vector titration by the analysis of the activity of viral reverse transcriptase. Tiziana Tonini, Pier Paolo Claudio, Antonio Giordano and Gaetano Romano. (2004): in Methods in Molecular Biology. Cell cycle control and dysregulation protocols. Part IV RETROVIRIDAE-BASED VECTORS: PROTOCOLS FOR LENTIVIRAL – AND RETROVIRAL-MEDIATED GENE TRANSFER TO ENGINEER CELL CULTURE SYSTEMS. Retroviral and lentiviral vector titration by the analysis of the activity of viral reverse transcriptase. Humana Press. Chapter 20.2004
Tiziana Tonini, Pier Paolo Claudio, Antonio Giordano and Gaetano Romano. Determination of functional viral titer by drug-resistance colony assay, expression, expression of green fluorescent protein, and beta-galactosidase staining Tiziana Tonini, Pier Paolo Claudio, Antonio Giordano and Gaetano Romano. (2004): in Methods in Molecular Biology. Cell cycle control and dysregulation protocols. Part IV RETROVIRIDAE-BASED VECTORS: PROTOCOLS FOR LENTIVIRAL – AND RETROVIRAL-MEDIATED GENE TRANSFER TO ENGINEER CELL CULTURE SYSTEMS. Determination of functional viral titer by drug-resistance colony assay, expression, expression of green fluorescent protein, and beta-galactosidase staining. Humana Press, Chapter 19.2004
Tiziana Tonini, Pier Paolo Claudio, Antonio Giordano and Gaetano Romano. Transient production of retroviral-and lentiviral-based vectors for the transduction of mammalian cells. Tiziana Tonini, Pier Paolo Claudio, Antonio Giordano and Gaetano Romano. (2004): in Methods in Molecular Biology. Cell cycle control and dysregulation protocols. Part IV RETROVIRIDAE-BASED VECTORS: PROTOCOLS FOR LENTIVIRAL – AND RETROVIRAL-MEDIATED GENE TRANSFER TO ENGINEER CELL CULTURE SYSTEMS. Transient production of retroviral-and lentiviral-based vectors for the transduction of mammalian cells. Humana Press, Chapter 18.2004
Claudio, F., Claudio, P.P. I tumori della lingua. Claudio, F., Claudio, P.P. (2003): I tumori della lingua. Capitolo 36. In Mazzeo, F., Forestieri, P. Ed. Piccin Nuova Libraria Padova. Trattato di Chirurgia Oncologica. Vol 2, pag. 39.1-39.42.2003
Montella, M., Gallipoli, A., Lorusso, A., Creazzola, S., Claudio, P.P., D’Errico, G. L’organizzazione della lotta contro i tumori Montella, M., Gallipoli, A., Lorusso, A., Creazzola, S., Claudio, P.P., D’Errico, G. (2003): L’organizzazione della lotta contro i tumori. Capitolo 36. In Mazzeo, F., Forestieri, P. Ed. Piccin Nuova Libraria Padova. Trattato di Chirurgia Oncologica. Vol 1, pag. 36.1-36.23.2003
Claudio PP, Giordano A. Preparation of retroviral vectors for cell cycle-targeted gene therapy of lung cancer. Claudio PP, Giordano A. (2003): Preparation of retroviral vectors for cell cycle-targeted gene therapy of lung cancer. In Barbara Driscoll (Ed.) Lung Cancer, volume II, Diagnostic and therapeutic methods and reviews. Methods Mol Med. Humana Press. 75: 591-605.2003
Claudio P. P., Giordano A. RB1 and RB2. Claudio P. P., Giordano A. (2000): RB1 and RB2. In Pass H.I., Mitchell J.B., Johnson D.H., Turrisi A.T., Minna J.D. (Ed.) Lung Cancer: Principles and Practice. Lippincott Williams & Wilkins. 7: 133-1552000
Howard C.M., Claudio P.P., Carbone M., Giordano A. SV40 and Human Cancer. Howard C.M., Claudio P.P., Carbone M., Giordano A. (1998): SV40 and Human Cancer. in Samuels, S.W. and Upton, A.C. Genes, Cancer and Ethics In the Work Environment. OEM Press, Beverly, MA. 167-174.1998
De Luca A., Baldi A., Claudio P.P., Howard C.M., Campisi S., Giordano A., Condorelli G. The retinoblastoma gene and its role in cancer and differentiation. De Luca A., Baldi A., Claudio P.P., Howard C.M., Campisi S., Giordano A., Condorelli G. (1995): The retinoblastoma gene and its role in cancer and differentiation. In Future Trends in Endocrinology. Ares-Serono Symposia Series-Frontiers in Endocrinology 14: 197-206.1995

Book

Claudio P.P., Vogiatzi, V., Editors. “Cutting edge therapies for cancer in the 21st century”. Claudio P.P., Vogiatzi, V., Editors. “Cutting edge therapies for cancer in the 21st century”. Bentham, May 2014. eISBN:978-1-60805-880-8, 2014 
ISBN:978-1-60805-881-5.2014
Claudio, P.P., Niles, R.M., Editors. “Nutrition and Cancer, from Epidemiology to Biology”. Claudio, P.P., Niles, R.M., Editors. “Nutrition and Cancer, from Epidemiology to Biology”. Bentham, August 2012. DOI: 10.2174/97816080544731120101
eISBN: 978-1-60805-447-3, 2012
ISBN: 978-1-60805-506-72012
Califano L., Claudio P.P. Parotid tumors. Califano L., Claudio P.P. (1995): Parotid tumors. Ed. Scientifiche Italiane. Napoli, 1-1481995
Claudio P.P., Savastano G. Cutaneous tumors of the face. Reconstructive surgery after ablation. Claudio P.P., Savastano G. (1992): Cutaneous tumors of the face. Reconstructive surgery after ablation. Ed. Scientifiche Italiane. Napoli, 1 - 160.1992

Editorial Commentary

Candace M. Howard, Jagan Valluri, and Pier Paolo Claudio. Functional drug response assay for cancer stem cells in the era of precision medicine. Candace M. Howard, Jagan Valluri, and Pier Paolo Claudio. Functional drug response assay for cancer stem cells in the era of precision medicine. Translational Medicine Reports (Invited Editorial), vol 1 (1), 2017. DOI: http://dx.doi.org/10.4081/tmr.6421 .2017
Candace M. Howard, Jagan Valluri, and Pier Paolo Claudio. T The Future of Precision Medicine in Oncology: Targeting Cancer Stem Cells. Candace M. Howard, Jagan Valluri, and Pier Paolo Claudio. The Future of Precision Medicine in Oncology: Targeting Cancer Stem Cells. Clinics in Oncology (Invited Editorial), 2017, Vol. 2, Article 1187.2017

Clinical Trial

Sammartino G, Tia M, Marenzi G, di Lauro AE, D'Agostino E, Claudio PP, Use of autologous platelet-rich plasma (PRP) in periodontal defect treatment after extraction of impacted mandibular third molars. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2005 Jun;63(6):766-702005

Comment

Vogiatzi P, Claudio PP, Efficacy of abiraterone acetate in post-docetaxel castration-resistant prostate cancer. Expert review of anticancer therapy, 2010 Jul;10(7):1027-302010
Gray SG, Guo X, Kedra D, Teh BT, Guo X, Min HQ, Correspondence re: P. P. Claudio et al., Mutations in the retinoblastoma-related gene RB2/p130 in primary nasopharyngeal carcinoma. Cancer Res., 60: 8-12, 2000. Cancer research, 2001 Aug 1;61(15):5950-32001
Claudio PP, Immunohistochemical investigation of new suppressor oncogene p130 in oral squamous cell carcinoma, vol.35 (1999), 321-325. Oral oncology, 2000 Sep;36(5):4972000

Editorial

Vattemi E, Claudio PP, Gene therapy for lung cancer: practice and promise. Annali italiani di chirurgia, 2004 May-Jun;75(3):279-89

Presentations

National and International Invited Seminars/Lectures, Cancer Stem Cells to Advance Functional Medicine in the Era of Precision Oncology, SICMF, Naples, Italy06/2025
National and International Invited Seminars/Lectures, Using Cancer Stem Cells to Advance Functional Medicine in the Era of Precision Oncology.
Pier Paolo Claudio. AACR Meeting 2025, March 10 - 13.
Oral presentation to the Plenary Session at AACR 2025, Boston., AACR, Boston
03/2025
National and International Invited Seminars/Lectures, Relationship of cancer stem cell functional assay and objective response rate of patients with recurrent platinum-resistant ovarian cancer in a randomized trial.

Oral presentation to the Gynecology Oncology Plenary Session at ASCO 2024, Chicago, IL., ASCO, Chicago
06/2024
National and International Invited Seminars/Lectures, Precision Medicine Trial for Newly Diagnosed High-Grade Gliomas., NRG Oncology, Philadelphia, PA07/2023
National and International Invited Seminars/Lectures, Precision medicine through cancer stem cells., University Federico II of Naples, Naples, Italy03/2023
National and International Invited Seminars/Lectures, Multi-institutional randomized phase-3 trial comparing cancer stem cell-targeted vs physician-choice treatments in patients with recurrent high-grade gliomas (NCT03632135), SNO/ASCO CNS Clinical Trial and Brain Metastasis Conference, Toronto, Canada08/2022
National and International Invited Seminars/Lectures, Recurrent Anaplastic Green Ependymoma Supplement Study (RAGES study), BRAIN TUMOR CENTER NEURO-ONCOLOGY CLINICAL RESEARCH DAY Seattle, Seattle10/2021
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: Precision medicine through a functional cancer stem cells assay and the potential of green chemotherapy to improve patients’ outcomes, Cancer Grand Rounds, Seattle Science Foundation., Seattle08/2021
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: ChemoID - Cancer Stem Cell Drug Response Assay to Personalize Cancer Management., Temple University - FELS INSTITUTE, Philadelphia, PA04/2019
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: ChemoID - Cancer Stem Cell Drug Response Assay to Personalize Cancer Management., Louisiana Sate University, New Orleans04/2019
State/Local Invited Seminars/Lectures, CANCER GRAND ROUNDS: ChemoID - Use of Cancer Stem Cell Drug Response Assay to Improve the Outcome of Cancer Patients, UMMC, Jackson MS03/2019
National and International Invited Seminars/Lectures, Prospective Analysis of Chemo-predictive Assay to Target Cancer Stem Cells in Glioblastoma Patients, Cancer Stem Cell Meeting, Austria12/2018
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: Personalizing treatment in the management of cancer. School of Medicine, University of Salerno, Italy, Salerno, Italy06/2018
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: ChemoID- personalizing treatment in the management of newly diagnosed and recurrent glioblastoma, PennState University, Hershey, PA05/2018
National and International Invited Seminars/Lectures, Prospective Analysis of Chemo-predictive Assay to Target Cancer Stem Cells in Glioblastoma Patients., Society of NeuroOncology Annual Meeting, New Orleans04/2018
State/Local Invited Seminars/Lectures, Personalizing treatment in the management of cancer., UMMC-School of Dentistry, Jackson, MS03/2018
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: ChemoID- personalizing treatment in the management of newly diagnosed and recurrent glioblastoma, University of CIncinnati, Cincinnati, OH03/2018
National and International Invited Seminars/Lectures, Efficacy of in vitro ChemoID guided drug selection for palliative chemotherapy in advanced recurrent ovarian adenocarcinoma: a case study., MD Anderson, Houston10/2017
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: Prospective Analysis of Chemo-predictive Assay to Target Cancer Stem Cells in Glioblastoma Patients, Toledo University, Toledo, OH06/2017
National and International Invited Seminars/Lectures, ChemoID a Chemo-predictive Assay to Target Cancer Stem Cells in Head and Neck Cancer Patients, International Meeting INTHEMA, Naples, Italy03/2017
National and International Invited Seminars/Lectures, ChemoID is a Chemo-predictive Assay to Target Cancer Stem Cells in Cancer Patients., Italian Institute of Technology (ITT), Genova, Italy03/2017
National and International Invited Seminars/Lectures, Prospective Analysis of Chemo-predictive Assay to Target Cancer Stem Cells in Glioblastoma Patients, International Cancer Study & Therapy Conference, Baltimore02/2017
Regional Invited Seminars/Lectures, Prospective Analysis of Chemo-predictive Assay to Target Cancer Stem Cells in Glioblastoma., Southern Regional Meeting, New Orleans02/2017
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: Chemosensitivity assay for targeting cancer stem-like cells in Glioblastoma., CAMC Hospital, Charleston, WV12/2016
National and International Invited Seminars/Lectures, Prospective Analysis of Chemo-Predictive Assay for Targeting Cancer Stem Cells in Glioblastoma Patients, Cleveland Clinic, Cancer Stem Cell Conference, Cleveland, OH09/2016
National and International Invited Seminars/Lectures, Development of Innate Immune Enhancing Botanicals and Identification of Tumor-Specific Chemotherapy/Botanical Combinations, University Federico II of Naples, Naples, Italy05/2016
State/Local Invited Seminars/Lectures, NEURO-ONCOLOGY GRAND ROUNDS: Chemosensitivity assay for targeting cancer stem-like cells in malignant solid tumors., UMMC Neuro-Oncology, Jackson, MS04/2016
National and International Invited Seminars/Lectures, Chemosensitivity assay for targeting cancer stem-like cells in malignant solid tumors of the head and neck, 23rd International meeting of Head and Neck Academicians, Naples, Italy04/2016
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: Chemosensitivity assay for targeting cancer stem-like cells in Glioblastoma., West Virginia University Hospital, Morgantown, WV02/2016
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: Chemosensitivity assay for targeting cancer stem-like cells in Glioblastoma, West Virginia University Hospital, Charleston, WV02/2016
National and International Invited Seminars/Lectures, CANCER GRAND ROUNDS: Chemosensitivity assay for targeting cancer stem-like cells in malignant solid tumors., University of Cincinnati, Comprehensive Cancer Center and University Hospitals, Cincinnati OH09/2014
National and International Invited Seminars/Lectures, Chemosensitivity assay for targeting cancer stem-like cells in malignant solid tumors., OleMiss, Oxford, MS09/2014

Honors, Awards, and Recognition

https://www.uc.edu/news/articles/2025/04/chemoid-test-leads-to-better-outcomes-in-platinum-resistant-ovarian-cancer.html, Press Release2025
https://www.news-medical.net/news/20250404/ChemoID-test-leads-to-better-outcomes-in-platinum-resistant-ovarian-cancer.aspx, Press Release2025
https://www.insideprecisionmedicine.com/topics/oncology/brain-cancer/stem-cell-based-treatment-selection-assay-led-to-improved-recurrent-glioblastoma-survival/, Press Release2025
https://www.stemcellsciencenews.com/newsletter/206290/, Press Release2025
Breakthrough Device Designation (BDD) status is awarded to ChemoID Assay by the Food and Drug Administration (FDA) to diagnose and treat unmethylated MGMT promoter glioblastoma, FDA2024
https://www.businesswire.com/news/home/20190917005129/en/Immuno-oncology-Innovator-Vesselon-Expands-Portfolio-Patented-Technology, Press Release2024
https://www.uc.edu/news/articles/2023/05/study-finds-chemoid-platform-predicted-treatments-lead-to-longer-survival.html, Press Release2024
https://www.news-medical.net/news/20230505/Cancer-stem-cell-test-can-lead-to-increased-survival-for-patients-with-glioblastoma.aspx, Press Release2024
https://www.news-medical.net/news/20230505/Cancer-stem-cell-test-can-lead-to-increased-survival-for-patients-with-glioblastoma.aspx, Press Release2024
https://www.psychreg.org/chemoid-platform-predicted-treatments-lead-longer-survival-glioblastoma-patients/, Perss Release2024
https://www.m3india.in/contents/clinical_news/study-chemoid-platform-predicted-treatments-lead-to-longer-survival-for-glioblastoma?feed=97390114, Pres Release2024
https://www.youtube.com/watch?v=YaD8-Y6QtB0, Press Release2024
https://www.medimagazine.it/glioblastoma-piattaforma-chemoid-aumenta-la-sopravvivenza/, Press Release2024
https://tvfcommunications.com/blog/cancer-treatment-is-getting-personal/, Press Release2024
https://clpmag.com/disease-states/cancer/unknown-other-cancer/chemoid-test-can-lead-to-longer-glioblastoma-patient-survival/, Press Release2024
https://www.labmedica.com/immunology/articles/294797119/cancer-stem-cell-test-improves-survival-of-patients-with-deadly-brain-tumor.html, Press Release2024
https://ichgcp.net/clinical-trials-registry/NCT03949283, Press Release2024
https://www.wvgazettemail.com/news/health/new-technology-develops-better-personalized-cancer-treatments/article_9c2a1775-c04a-5a02-a53c-2396fb8d8f1c.html, Press Release2024
https://www.thehealthsite.com/diseases-conditions/cancer/heath-tech-4-innovative-technologies-that-will-change-cancer-treatment-734440/, Press Release2024
https://www.tgh.org/institutes-and-services/cancer-institute/neurological-cancer-program, Press Release2023
https://www.uc.edu/news/articles/2022/05/vjoncology--chemoid-trial-shows-increased-survival.html, Press Release2022
https://www.medscape.com/viewarticle/972276, Press Release2022
https://www.mdedge.com/hematology-oncology/article/253824/cns/brain-cancer/assay-guided-chemo-recurrent-glioma-linked, Press Release2022
https://www.cancertherapyadvisor.com/home/news/conference-coverage/american-association-for-cancer-research-aacr/aacr-2022/high-grade-glioma-assay-guided-therapy-improves-survival/, Press Release2022
https://www.pvhomed.com/new-technology-is-making-a-difference-in-the-fight-against-cancer/, Press Release2022
https://www.uc.edu/news/articles/2022/05/vjoncology--chemoid-trial-shows-increased-survival.html, Press Release2022
https://www.thehealthsite.com/diseases-conditions/cancer/heath-tech-4-innovative-technologies-that-will-change-cancer-treatment-734440/, Press Release2022
https://www.ahn.org/services/cancer/types/brain/treatment.html, Press Release2021
www.uc.edu/news/articles/2019/01/n2062227.html, Press Release2019
https://www.umc.edu/news/News_Articles/2017/February/Researcher-s-goal--Find-the-best-chemo-for-each-patient.html, Press Release2017
Poster Communication Award, UMMC - The Center for Bioethics and Medical Humanities & the Rowland Medical Library2016
European Patent Serial Number 09721750.9 “Method for Stem Cell Production and Therapy”, issued on April 29, 2016., European Patent Office2016
U.S. Patent Serial Number: 9,316,632: “Methods of screening chemotherapeutic agents and treating cancer”, issued Feb 9, 2016., USPTO2016
https://nuemd.com/news/2016/09/22/3-new-technologies-field-cancer-treatment, Press Release2016
ChemoID trademark, allowed in 2016, USPTO2016
U.S. Patent Serial Number: 8,993,231: “Methods for stem cells production and therapy”, issued March 31, 2015., USPTO2015
U.S. Patent Serial Number 8,454,937: “Method and composition for the site-selective delivery using viruses encapsulated in microbubbles”, issued on June 4, 2013., USPTO2013
Stem Cell Research Award, Lion’s Club Fondi, Italy2008
BioMedical Sciences Award, International Award “Sebetia-Ter”2007
Outstanding Achievements in Gene Therapy Award, Rotary Club – Napoli2004
U.S. Patent Serial Number 10/250,805: “Method for quantification of recombinant viruses”, issued on February 12, 2004., USPTO2004
U.S. Patent Serial Number 6596698. “Methods of inhibiting smooth muscle cell proliferation and preventing restenosis with a vector expressing RB2/p130”, issued on July 22, 2003., USPTO2003
Who’s Who in Science and Engineering, Who’s Who in Science and Engineering2002
Outstanding achievement in cancer research., Lions Club Napoli-Mergellina1999
Research Fellowship Award, Associazione Leonardo di Capua”, Napoli, Italy1999
Research Fellowship from the “Associazione Leonardo di Capua”, Napoli, Italy, for a research project on Nasopharyngeal Cancer., Associazione Leonardo di Capua1999
Research Fellowship Award, American-Italian Cancer Foundation, New York, USA.1995
Research Fellowship from the American-Italian Cancer Foundation, New York, USA., American-Italian Cancer Foundation1995
Summa cum Laude, University Federico II of Naples, Italy1994
Research Fellowship Award, Lega Nazionale Lotta Contro I Tumori” of the National Institute of Tumor “Fondazione Senatore Pascale,” Naples, Italy.1994
Research Fellowship from “Lega Nazionale Lotta Contro I Tumori” of the National Institute of Tumor “Fondazione Senatore Pascale,” Naples, Italy., National Cancer Institute, Italy1994
Summa cum Laude, University Federico II of Naples, Italy1989
Fellowship Training Award, Head & Neck Surgery at the University of Naples “Federico II,” Italy.1989
Training Fellowship awarded for training in Head & Neck Surgery at the University of Naples “Federico II,” Italy., University of Naples “Federico II,” Italy.1989
II Edition of the National Award for Young Researchers “A. Schweitzer”, Italy., II Edition of the National Award for Young Researchers “A. Schweitzer”, Italy1987

Professional Membership and Service

International non-transfusional Hemocomponents Academy (intHEMA)., Officer, Vice President2023 - Present
Society of Neuro-Oncology (SNO), Member2019 - Present
International non-transfusional Hemocomponents Academy (intHEMA)., Officer, Vice President2016 - Present
International non-transfusional Hemocomponents Academy (intHEMA)., Founder Member2015 - Present
Mississippi Academy of Sciences, Member2015 - Present
American Association Clinical Oncology (ASCO)., Member2011 - Present
American Society for Gene & Cell Therapy (ASGCT)., Member2009 - Present
Head & Neck Optical Diagnostics Society (HNODS)., Member2009 - Present
American Association for Cancer Research (AACR), Member2000 - Present
European Association for Cranio-Maxillo-Facial Surgery (E.A.C.M.F.), Member1991 - Present
Societa’ italiana dei Giovani Chirurghi (S.P.I.G.C.), Member1990 - Present
Societa' Italiana di Chirurgia Maxillo Facciale (S.I.C.M.F.), Member1990 - Present

Committee Service

CCRI membership committee, Member2025 - Present
CCRI Experimental Therapeutics Program, Member2025 - Present
Dept. of Pharmacology hiring committee, Chair2024 - Present
Intellectual Property Executive Committee, Member2021 - Present
Intellectual Property Oversight Committee, Chair2021 - Present
CCRI Experimental Therapeutics Program, Member2018 - 2023
Scientific Leadership Council, University of Mississippi Medical Center, Cancer Center & Research Institute., Member2017 - 2023
SCHOOL OF DENTISTRY-RESEARCH ADVISORY, Member2017 - Present

Teaching Experience

Medicine, Course, Course Director, Radiobiology for Radiation Oncology ResidentsAnnual 2023-present
MSCI740, Medicine, Lecture, Lecturer, Master of Science in Clinical Investigation (MSCI 740) courseSummer 2023-present
Medicine, Lecture, Lecturer, Mechanisms of Drug ActionSummer 2023-present
Pharm 792-4, Medicine, Lecture, Lecturer, PHARM 792 Research in Pharmacology and ToxicologyAnnual 2023-
SOM614, Medicine, Lecture, Course Presenter, SOM 614Fall 2015-present
Medicine, Course, Course Presenter, Radiobiology for Radiation Oncology ResidentsAnnual 2015-2023 - 2023

Directed Student Learning

Supervised Research, Advised: Turner Smith2025 - Present
Dissertation Defense Committee Member, Advised: Francesca Spirito2025 - Present
Supervised Research, Advised: John Holly Tacket2023 - Present
Dissertation Committee Chair, Advised: Imani Kirven2023 - Present
Dissertation Defense Committee Member, Advised: Elliot Varney2019 - 2024
Dissertation Defense Committee Member, Advised: Juliana Sitta2018 - 2024
Supervised Research, Advised: Grace Thaggard2017 - 2019
Internship Advisor, Advised: Afsana Jahan2017 - 2018
Internship Advisor, Advised: Brooke Bell2016 - 2023
Internship Advisor, Advised: Litty Thomas2015 - 2017

Fellows supervised

CCRI, Post-Doc Advisor, 1 fellows supervised01/2015 - 01/2023

Residency Training

Biomedical Imaging & Engineering, Research Advisor2019 - 12/2024