Abhay Bhatt, MD

Abhay Bhatt, MD

Professor

Department:
SOM-Peds-Neonatology

Email:
abhatt@umc.edu

Work Phone:
(601) 815-7100

Biography

Dr. Abhay Bhatt is a Professor of Pediatrics and Director of Research in the division of newborn medicine and the department of Pediatrics at UMMC. His primary research interests are hypoxic-ischemic (HI), oxygen, inflammation, and steroid-induced injury to the developing brain. His long-term research goals are to understand how to target molecular mechanisms causing ongoing brain damage following these insults in order to develop improved strategies for the prevention and treatment of brain injury in newborn infants and to develop corticosteroids regimens for the treatment of chronic lung disease of prematurity and vasopressor-resistant hypotension without any major toxicity, particularly neurotoxicity. As director of Research, Dr. Bhatt looks forward to continuing to sustain and expand discovery in the division and thus achieving the vision of Children’s Mississippi to touch the life of every child in Mississippi and help them reach their full potential. As a neonatologist, Dr. Bhatt supports the mission of the newborn division to achieve the highest standards of performance to provide support for critically ill and preterm newborn infants and their families through compassionate clinical care. He also supervises quality improvement projects in the NICU. Dr. Bhatt has a keen interest in educational activities to develop outstanding health care professionals.

Education

Millsaps College, Jackson, MS, Certificate of Completion, Business Advantage Program2013
University of Rochester, Children’s Hospital at Strong, Rochester, NY, MD, Neonatal-Perinatal Medicine1999
Children’s Medical Center at Brooklyn, State University of New York, New York, NY, MD, Pediatrics1996
Gujarat University, Sheth K.M. School of P.G. Medicine & Research, Ahmedabad, India, MD, Pediatrics1992
Gujarat University, Smt. N. H. L. M. Medical College, Ahmedabad, India, MBBS, Medicine1989

Specialty Certification Licensure

Certification, Diplomate in Neonatal-Perinatal Medicine, The American Board of Pediatrics10/1999 - Present
Certification, Neonatal Resuscitation Program (NRP) Provider06/2015
Licensure, Mississippi State Board of Medical Licensure07/2012 - 06/2015
Certification, Diplomate of The American Board of Pediatrics, The American Board of Pediatrics10/1996 - 12/2013
Licensure, Mississippi State Medical Board03/2000 - 06/2012

Current Positions

Physician Liaison/Medical Director, NICU at MHG, School of Medicine01/2018 - Present
Director of Research, Newborn Division, School of Medicine, Department of Pediatrics11/2016 - Present
Professor, School of Medicine, Department of Pediatrics07/2015 - Present
Team Leader VON Database, School of Medicine2012 - Present
The University of Mississippi Medical Center
Jackson, Mississippi 39216

Academic Appointments or Other Previous Appointments

Clinical Science Director of CDDR, Center for Developmental Disorders Research (CDDR), School of Medicine05/2014 - 10/2017
Vice Chair, University of Mississippi Medical Center, Jackson, MS, School of Medicine, Department of Pediatrics2014 - 10/2016
Interim Chief, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics07/2012 - 03/2013
Associate Professor, University Of Mississippi Medical Center, School of Medicine, Department of Pediatrics07/2010 - 06/2015
Medical Director, Newborn Intensive Care Unit, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics2009 - 12/2013
Assistant Professor, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics2006 - 06/2010
Consultant Neonatologist, Ahmedabad, India2004 - 12/2005
Assistant Professor, University of Mississippi Medical Center, School of Medicine, Department of Pediatrics04/2000 - 09/2003

Sponsored Program Funding

Extramural, A Phase 2/3 Randomized, Double-blind, Palivizumab-controlled Study to Evaluate the Safety of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in High-risk Children (MEDLEY), Medlmmune, Inc08/2019 - Present
Extramural, D5290C00004- A Phase 3 Randomized, Double-blind, Placebo-controlled Study to
Evaluate the Safety and Efficacy of MEDI8897, a Monoclonal Antibody With an Extended Half-
Life Against Respiratory Syncytial Virus, In Healthy Late Preterm and Term Infants (MELODY), Medlmmune, Inc		08/2019 - Present
Extramural, A Phase 2b, Multicenter, Randomized, Open-Label, Controlled, 3-Arm Study to Evaluate
the Clinical Efficacy and Safety of SHP607 in Preventing Chronic Lung Disease Through 12
Months Corrected Age Compared to Standard Neonatal Care in Extremely Premature Infants, Shire		03/2019 - Present
Extramural, Multicenter, Prospectively Defined Observational Registry with Retrospective Data Collection, Evaluating Premature and Term-Near-Term Neonates with Pulmonary Hypertension Receiving Inhaled Nitric Oxide via Invasive or Noninvasive Ventilator Support at US Centers., Mallinckrodt Pharmaceuticals, Inc04/2018 - 08/2020
Extramural, Medical Optimization & Management of Pregnancies with Overt Type 2 Diabetes (MOMPOD)., NICHD03/2018 - Present
Extramural, A Phase 2b Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Preterm Infants., Medlmmune, Inc09/2017 - 03/2019
Extramural, A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of a Human Monoclonal Antibody, REGN2222, for the Prevention of Medically Attended RSV Infection in Preterm Infants., Regeneron Pharmaceuticals. Inc.06/2017 - 06/2018
Extramural, Determination of the rhIGF-1/rhIGFBP-3 Dose, Administered as a Continuous Infusion Required to Establish and Maintain Longitudinal Serum IGF-1 Levels Within Physiological Levels in Premature Infants, to Prevent Retinopathy of Prematurity. A Phase 2, Randomized Controlled, Assessor-blind, Dose-confirming, Pharmacokinetic, Safety and Efficacy, Multicenter Study, Shire Human Genetic Therapies, Inc09/2015 - 07/2016

Publications

United States Patent Application

Fan LW, Bhatt AJ Serial No.: 16/891,789: COMPOSITIONS, SYSTEMS, AND METHODS FOR TREATING OR REDUCING HYPOXIA-ISCHEMIA INDUCED BRAIN DAMAGE AND NEUROBEHAVIORAL DYSFUNCTION IN NEONATES2020

Journal Article

Feng Y, Famuyide M, Bhatt AJ Dexamethasone decreases insulin-like growth factor-I and -II via a glucocorticoid receptor dependent mechanism in developing rat brain. Neuro Endocrinol Lett. 2013;34(7):624-342013
Fan LW, Carter K, Bhatt A, Pang Y, Rapid transport of insulin to the brain following intranasal administration in rats. Neural regeneration research, 2019 Jun;14(6):1046-10512019
Narang R, Carter K, Muncie C, Pang Y, Fan LW, Feng Y, Ojeda NB, Bhatt AJ, Intrauterine growth restriction and neonatal hypoxic ischemic brain injury causes sex-specific long-term neurobehavioral abnormalities in rats. Journal of neuroscience research, 2019 Jun;97(6):661-6722019
Lan KM, Tien LT, Cai Z, Lin S, Pang Y, Tanaka S, Rhodes PG, Bhatt AJ, Savich RD, Fan LW, Erythropoietin Ameliorates Neonatal Hypoxia-Ischemia-Induced Neurobehavioral Deficits, Neuroinflammation, and Hippocampal Injury in the Juvenile Rat. International journal of molecular sciences, 2016 Feb 26;17(3):2892016
Pang Y, Lin S, Wright C, Shen J, Carter K, Bhatt A, Fan LW, Intranasal insulin protects against substantia nigra dopaminergic neuronal loss and alleviates motor deficits induced by 6-OHDA in rats. Neuroscience, 2016 Mar 24;318:157-652016
Fan LW, Bhatt A, Tien LT, Zheng B, Simpson KL, Lin RC, Cai Z, Kumar P, Pang Y, Exposure to serotonin adversely affects oligodendrocyte development and myelination in vitro. Journal of neurochemistry, 2015 May;133(4):532-432015
Feng Y, Kumar P, Wang J, Bhatt AJ, Dexamethasone but not the equivalent doses of hydrocortisone induces neurotoxicity in neonatal rat brain. Pediatric research, 2015 May;77(5):618-242015
Lan KM, Tien LT, Pang Y, Bhatt AJ, Fan LW, IL-1 receptor antagonist attenuates neonatal lipopolysaccharide-induced long-lasting learning impairment and hippocampal injury in adult rats. Toxicology letters, 2015 Apr 2;234(1):30-392015
Pang Y, Tien LT, Zhu H, Shen J, Wright CF, Jones TK, Mamoon SA, Bhatt AJ, Cai Z, Fan LW, Interleukin-1 receptor antagonist reduces neonatal lipopolysaccharide-induced long-lasting neurobehavioral deficits and dopaminergic neuronal injury in adult rats. International journal of molecular sciences, 2015 Apr 17;16(4):8635-542015
Feng Y, Bhatt AJ, Corticosteroid responses following hypoxic preconditioning provide neuroprotection against subsequent hypoxic-ischemic brain injury in the newborn rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2015 Aug;44:6-132015
Bhatt A, Fan LW, Pang Y, Strategies for myelin regeneration: lessons learned from development. Neural regeneration research, 2014 Jul 15;9(14):1347-502014
Feng Y, Lu S, Wang J, Kumar P, Zhang L, Bhatt AJ, Dexamethasone-induced neuroprotection in hypoxic-ischemic brain injury in newborn rats is partly mediated via Akt activation. Brain research, 2014 Nov 17;1589:68-772014
Fan LW, Kaizaki A, Tien LT, Pang Y, Tanaka S, Numazawa S, Bhatt AJ, Cai Z, Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats. Neuroscience, 2013 Jun 14;240:27-382013
Kaizaki A, Tien LT, Pang Y, Cai Z, Tanaka S, Numazawa S, Bhatt AJ, Fan LW, Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide. Journal of neuroinflammation, 2013 Apr 5;10:452013
Tien LT, Kaizaki A, Pang Y, Cai Z, Bhatt AJ, Fan LW, Neonatal exposure to lipopolysaccharide enhances accumulation of α-synuclein aggregation and dopamine transporter protein expression in the substantia nigra in responses to rotenone challenge in later life. Toxicology, 2013 Jun 7;308:96-1032013
Bhatt AJ, Feng Y, Wang J, Famuyide M, Hersey K, Dexamethasone induces apoptosis of progenitor cells in the subventricular zone and dentate gyrus of developing rat brain. Journal of neuroscience research, 2013 Sep;91(9):1191-2022013
Pang Y, Fan LW, Tien LT, Dai X, Zheng B, Cai Z, Lin RC, Bhatt A, Differential roles of astrocyte and microglia in supporting oligodendrocyte development and myelination in vitro. Brain and behavior, 2013 Sep;3(5):503-142013
Feng Y, Rhodes PG, Bhatt AJ, Dexamethasone pre-treatment protects brain against hypoxic-ischemic injury partially through up-regulation of vascular endothelial growth factor A in neonatal rats. Neuroscience, 2011 Apr 14;179:223-322011
Feng Y, Rhodes PG, Bhatt AJ, Hypoxic preconditioning provides neuroprotection and increases vascular endothelial growth factor A, preserves the phosphorylation of Akt-Ser-473 and diminishes the increase in caspase-3 activity in neonatal rat hypoxic-ischemic model. Brain research, 2010 Apr 14;1325:1-92010
Hill J, Dierker D, Neil J, Inder T, Knutsen A, Harwell J, Coalson T, Van Essen D, A surface-based analysis of hemispheric asymmetries and folding of cerebral cortex in term-born human infants. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010 Feb 10;30(6):2268-762010
Feng Y, Rhodes PG, Liu H, Bhatt AJ, Dexamethasone induces neurodegeneration but also up-regulates vascular endothelial growth factor A in neonatal rat brains. Neuroscience, 2009 Jan 23;158(2):823-322009
Feng Y, Bhatt AJ, Fratkin JD, Rhodes PG, Neuroprotective effects of sodium orthovanadate after hypoxic-ischemic brain injury in neonatal rats. Brain research bulletin, 2008 May 15;76(1-2):102-82008
Feng Y, Rhodes PG, Bhatt AJ, Neuroprotective effects of vascular endothelial growth factor following hypoxic ischemic brain injury in neonatal rats. Pediatric research, 2008 Oct;64(4):370-42008
Feng Y, Liu YM, Leblanc MH, Bhatt AJ, Rhodes PG, Grape seed extract given three hours after injury suppresses lipid peroxidation and reduces hypoxic-ischemic brain injury in neonatal rats. Pediatric research, 2007 Mar;61(3):295-3002007
Maniscalco WM, Watkins RH, Pryhuber GS, Bhatt A, Shea C, Huyck H, Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons. American journal of physiology. Lung cellular and molecular physiology, 2002 Apr;282(4):L811-232002
Bhatt AJ, Pryhuber GS, Huyck H, Watkins RH, Metlay LA, Maniscalco WM, Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia. American journal of respiratory and critical care medicine, 2001 Nov 15;164(10 Pt 1):1971-802001
Bhatt AJ, Amin SB, Chess PR, Watkins RH, Maniscalco WM, Expression of vascular endothelial growth factor and Flk-1 in developing and glucocorticoid-treated mouse lung. Pediatric research, 2000 May;47(5):606-132000
Pang Y, Dai X, Roller A, Carter K, Paul I, Bhatt AJ, Lin RC, Fan LW, Early Postnatal Lipopolysaccharide Exposure Leads to Enhanced Neurogenesis and Impaired Communicative Functions in Rats. PloS one, 2016;11(10):e0164403
Tien LT, Lee YJ, Pang Y, Lu S, Lee JW, Tseng CH, Bhatt AJ, Savich RD, Fan LW, Neuroprotective Effects of Intranasal IGF-1 against Neonatal Lipopolysaccharide-Induced Neurobehavioral Deficits and Neuronal Inflammation in the Substantia Nigra and Locus Coeruleus of Juvenile Rats. Developmental neuroscience, 2017;39(6):443-459
Ramarao S, Pang Y, Carter K, Bhatt A, Azithromycin Protects Oligodendrocyte Progenitor Cells against Lipopolysaccharide-Activated Microglia-Induced Damage. Developmental neuroscience, 2022;44(1):1-12

Abstracts

Dankhara N*, Lee JW, Ojeda N, Lu S, White E, Xu S, C Glendye C, Pang Y, Bhatt AJ and Fan L *SSPR Basic Science Young Investigator Award Finalist INTRANASAL INSULIN AND SEX-SPECIFIC EFFECTS ON LONG-TERM NEUROBEHAVIORAL OUTCOMES FOLLOWING HYPOXIC-ISCHEMIC BRAIN INJURY IN NEONATAL RATS. SSPR 2021, Abstract 1172021
Desai J, Famuyide M, Patel J, Kalikkot R, Bhatt A. Gender and Racial Disparities of Pulmonary Interstitial Emphysema among Preterm Infants: An Analysis of the National Kids' Inpatient Database. Pediatric Academic Societies 2017, San Francisco, CA, May 2017.2017
Desai J, Savich R, Patel J, Kalikkot R, Bhatt A. Significant Decrease in Critical Congenital Heart Disease in the Neonatal Period Presenting in the Emergency Department After Implementation of CCHD Screening: Analysis of a National Database. Pediatric Academic Societies 2017, San Francisco, CA, May 2017.2017
Narang R, Carter K, Muncie CB, Pang Y, Fan L-W, Feng Y, Ojeda N, Bhatt AJ. Novel model of hypoxic-ischemic brain damage in intra uterine growth restricted newborn rats. Southern Society for Pediatric Research, New Orleans, LA, February 2017.2017
Ramarao S, Pang Y, Carater K. Bhatt A. Macrolides Suppress LPS Induced Inflammatory In vitro Brain Injury Mediated by Microglia. Southern Society for Pediatric Research, New Orleans, LA, February 2017.2017
Fan L-W, Tien L-T,Lee JW, Lu S,Lin RCS, Dai X, Bhatt AJ,Pang Y. Neonatal Exposure to interleukin-1beta enhances adult vulnerability to rotenone neurotoxicity. The 46th Annual Meeting of the Society for Neuroscience, San Diego, CA, November 2016.2016
Bhatt AJ, Fan LW, Dai X, Pang Y Combined treatment of lipopolysaccharide and hyperoxia leads to enhanced neurodevelopment disturbances in neonatal rats. EPAS2015
Bhatt AJ, Feng Y, Kumar P. Hydrocortisone Pre-treatment Reduces Hypoxic Ischemic Brain Injury in Neonatal Rats. E-PAS2014: 4118.2992014
Pang Y Bhatt A, Fan LW, Dai X, Tien LT, Kumar P. The role of microglia in myelination: A friend or a foe. E-PAS2014. 3375.82014
Fan LW, Tien LT, Zhu H, Bhatt AJ, Kumar P, Pang Y Interleukin-1 receptor antagonist attenuates neonatal lipopolysaccharide-enhanced adult susceptibility to the neurodegenerative disorder induced by rotenone. E-PAS2014. 1546.6612014
Bhatt AJ, Feng Y, Kumar P. Hydrocortisone Pre-treatment Reduces Hypoxic Ischemic Brain Injury in Neonatal Rats. Journal of Investigative Medicine • Volume 62, Number 2, February 2014. A 4452014
Pang Y, Tien LT, Zheng B, Bhatt AJ, LIn RCS, Fan LW Do microglia play a role in myelination during development? Soc. Neurosci Abstr. The 43rd Annual Meeting of The Society for Neuroscience, San Diego, CA, Nov.9-13, 2013.2013
Fan LW, Tien LT, Cai Z, Bhatt AJ, Pang Y Intranasal administration of insulin-like growth factor-1 ameliorates dopaminergic neuronal injury and improves motor behavioral performance in juvenile rats following neonatal exposure to liopoplysaccharide Soc. Neurosci Abstr. The 43rd Annual Meeting of The Society for Neuroscience, San Diego, CA, Nov. 9-13, 2013.2013
Bhatt AJ, Feng Y, J Wang, M Famuyide Insulin Like Growth Factor- I Fails To Protect Against Dexamethasone-Induced Neurodegeneration In Neonatal Rats E-PAS2013: 1539.5442013
Feng Y, M Famuyide, Bhatt AJ Glucocorticoid Receptor Blocker Attenuates The Dexamethasone Induced Decrease of Insulin-Like Growth Factor-I and -II in Neonatal Rat Brain Presented at the 42nd International Neuroscience Conference, October 2012, New Orleans, LA2012
Bhatt AJ, Feng Y, J Wang, M Famuyide Dexamethasone but Not Hydrocortisone Decreases Neurogenesis in Neonatal Rats Presented at the 42nd International Neuroscience Conference, October 2012, New Orleans, LA2012
Bhatt AJ, Feng Y, Rhodes PG Dexamethasone but not hydrocortisone decreases proliferating cells in neonatal rat brains E-PAS2012: 1526.4372012
Feng Y, Rhodes PG, J Wang, Bhatt AJ Dexamethasone but not hydrocortisone induces apoptosis in neonatal brain and impairs learning and memory function in later life Presented at the 41th International Neuroscience Conference, November 2011, Washington DC2011
Feng Y, Rhodes PG, Bhatt AJ Dexamethasone induced neuroprotection is mediated in part via Akt activation in yypoxic−ischemic brain injury in newborn rats E-PAS2011: 4533.4782011
Bhatt AJ, Feng Y, Rhodes PG Hydrocortisone is safer than dexamethasone and provides similar neuroprotection against subsequent hypoxic−ischemic brain injury in neonatal rats E-PAS2011: 4533.4792011
Feng Y, Rhodes PG, Bhatt AJ Pituitary adrenal axis adaptation following hypoxic preconditioning provides neuroprotection against subsequent hypoxic-ischemic brain injury in newborn rats International Neuroscience Conference, November 2010, San Diego, CA2010
Bhatt AJ, Feng Y, Rhodes PG Dexamethasone but not the equivalent doses of hydrocortisone induces apoptosis and neurodegeneration in neonatal rat brain Presented at the 40th International Neuroscience Conference, November 2010, San Diego, CA, Program No. 727.72010
Feng Y, Rhodes PG, Bhatt AJ Corticosteroid responses following hypoxic preconditioning provide neuroprotection against subsequent hypoxic-ischemic brain injury in newborn rats E-PAS2010: 3744.4632010
Bhatt AJ, Feng Y, Rhodes PG Dexamethasone induces apoptosis and neurodegeneration in neonatal rat brain E-PAS2010: 3744.4792010
Feng Y, Rhodes PG, Bhatt AJ Dexamethasone induces apoptosis and neurodegeneration in neonatal rat brain Presented at the 39th International Neuroscience Conference, October 2009, Chicago, IL2009
Bhatt AJ, Feng Y, Rhodes PG Dexamethasone decreases Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-II in the neonatal rat brain E-PAS2009: 3871.3292009
Feng Y, Rhodes PG, Bhatt AJ Dexamethasone enhances up-regulation of vascular endothelial growth factor A mRNA expression after hypoxic-ischemic brain injury in neonatal rats Presented at the 38th International Neuroscience Conference, November 2008, Washington DC, Program No. 749.82008
Feng Y, Rhodes PG, Bhatt AJ Dexamethasone Increase Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor A (VEGF) mRNA Expression in the Neonatal Rat Brain E-PAS2008: 5828.182008
Bhatt AJ, Feng Y, Rhodes PG Hypoxic Preconditioning Augments and Preserves the Increase in the mRNA Expression of VEGF Isoforms by Hypoxia-Ischemia in Newborn Rat Brain E-PAS2008: 5828.362008
Feng Y, Rhodes PG, Bhatt AJ Dexamethasone increases total vascular endothelial growth factor A but decreases vascular endothelial growth factor A164 in neonatal rat brain Presented at the 37th International Neuroscience Conference, November 2007, San Diego, CA, Program No. 456.192007
Bhatt AJ, Feng Y, Rhodes PG Neuroprotective Effects of Vascular Endothelial Growth Factor A (VEGF A) following Hypoxic ischemic Brain Injury in Neonatal Rats E-PAS2007: 7350.32007
Bhatt AJ, Hutchins JM, Rhodes PG Hypoxia-Ischemia (HI) Increases Hypoxia-Inducible Factor-1a (HIF-1a) and Vascular Growth Factors (VEGF) in Developing Rat Brain Pediatric Research, 2003; 53, #4, Abstract #1971, 346A2003
Amin SB, Bhatt AJ, Maniscalco WM In-situ antibiotic therapy for confirmed percutaneous central venous catheter (PSC) infections in neonates Pediatric Research, 2001; 49: Abstract #13292001
Bhatt AJ, Watkins RH, Huyck H, Maniscalco WM Decreased Vascular Endothelial Growth Factor (VEGF), VEGF receptor (flt-1) and endothelial marker, PECAM, in premature baboons with chronic lung disease (CLD) American Journal of Respiratory and Critical Care Medicine, May 20002000
Bhatt AJ, Pryhuber GS, Huyck H, Watkins RH, Maniscalco WM Evidence for Disrupted Microvascular Development in Premature Human Infants Dying with bronchopulmonarydysplasia (BPD) American Journal of Respiratory and Critical Care Medicine, May 20002000
Bhatt AJ, Pryhuber GS, Huyck H, Watkins RH, Maniscalco WM Vascular dysmorphic changes in premature human infants dying with bronchopulmonarydysplasia Journal of Investigative Medicine, March 2000. 48, #2, Abstract # 1692000
Bhatt AJ, Watkins RH, Chess PR, Maniscalco WM Dexamethasone induces vascular endothelial growth factor (VEGF) and hypoxia inducible factor-like factor (HLF) mRNA abundance in postnatal mice American Journal of Respiratory and Critical Care Medicine Journal, March 1999; 159:3, A9001999
Bhatt AJ, Watkins RH, Chess PR, Maniscalco WM Vascular Endothelial Growth Factor (VEGF), VEGF Receptor (fLK-1) and Hypoxia Inducible factor-like factor (HLF) mRNA Abundance are Increased by Dexamethasone in Postnatal Mouse Lung Pediatric Research, 1999; 45:48A, Abstract #2751999
Talati C*, Lee JW, Lu S, Nielson T, Raval R, Prakash V, Ojeda N, Pang Y, Bhatt AJ and Fan L *SSPR BASIC SCIENCE YOUNG INVESTIGATOR AWARD Winner REDUCTION OF HYPOXIA-ISCHEMIA INDUCED EARLY BRAIN DAMAGEAND SENSORIMOTOR BEHAVIORAL DISTURBANCES BY INTRANASAL INSULIN TREATMENT IN NEONATAL RATS. J Clin Investi, 2019, Abstract 551
Ojeda NB, Intapad S, Carter AJ, Alexander BT, Bhatt A. Developmental origins of renal diseases: a translational approach. FASEB J. 2013;27:A919.1

Book Chapter

Bhatt AJ, Ryan RM Pulmonary Interstitial Emphysema. Medscape Reference. Updated October 09, 2013.2013
Bhatt AJ, Ryan RM Pulmonary Interstitial Emphysema EMedicine, 3 (5): topic 2596, 20022002

Presentations

Platform Presentations, INTRAPERITONEAL LIPOPOLYSACCHARIDE DISRUPTS EARLY NEURAL DEVELOPMENTAL PROGRAMS AND IMPAIRS BEHAVIORS IN NEONATAL RATS, Southern Society for Pediatric Research, New Orleans, Louisiana02/2016
Platform Presentations, COMBINED EFFECTS OF LIPOPOLYSACCHARIDE AND HYPEROXIA LEADS TO ENHANCED NEURODEVELOPMENTAL DISTURBANCES IN NEONATAL RATS, Southern Society for Pediatric Research, New Orleans, Louisiana02/2015
Scientific Presentations, Hydrocortisone Pre-treatment Reduces Hypoxic Ischemic Brain Injury in Neonatal Rats, Southern Society for Pediatric Research, New Orleans, LA02/2014
Poster Presentation, Insulin Like Growth Factor- I Fails To Protect Against Dexamethasone-Induced Neurodegeneration In Neonatal Rats, Pediatric Academic Societies- Society for Pediatric Research Annual Meeting, Washington, DC05/2013
Scientific Presentations, Insulin-like growth factor-1 fails to protect against dexamethasone-induced neurodegeneration in neonatal rats., Southern Society for Pediatric Research, New Orleans, LA02/2013
Scientific Presentations, Dexamethasone but Not Hydrocortisone Decreases Neurogenesis in Neonatal Rats, International Neuroscience Conference, San Diego, CA10/2012
Scientific Presentations, Glucocorticoid Receptor Blocker Attenuates The Dexamethasone Induced Decrease of Insulin-Like Growth Factor-I and -II in Neonatal Rat Brain, International Neuroscience Conference, San Diego, CA10/2012
Poster Presentation, Dexamethasone but Not Hydrocortisone Decreases Proliferating Cells in Neonatal Rat Brains, Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, Boston, MA04/2012
Platform Presentations, Dexamethasone but Not Hydrocortisone Decreases Proliferating Cells in Neonatal Rat Brains, Southern Society for Pediatric Research Annual Meeting, New Orleans, LA02/2012
Scientific Presentations, Dexamethasone induced neuroprotection is mediated in part via Akt activation in hypoxic-ischemic brain injury in newborn rats, Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, Denver, CO05/2011
Poster Presentation, Hydrocortisone is a safer than dexamethasone and provides similar neuroprotection against subsequent hypoxic-ischemic brain injury in neonatal rats, Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, Denver, CO05/2011
Scientific Presentations, Differences in the apoptotic neurodegenerative effects of different glucocorticoids on developing rat brain, Southern Society of Pediatric Research Annual Conference, New Orleans, LA02/2011
Scientific Presentations, Dexamethasone but not the equivalent doses of hydrocortisone induces apoptosis and neurodegeneration in neonatal rat brain, International Neuroscience Conference, San Diego, CA11/2010
Scientific Presentations, Pituitary Adrenal Axis Adaptation Following Hypoxic Preconditioning provides Neuroprotection Against Subsequent Hypoxic-Ischemic Brain Injury In Newborn Rats, International Neuroscience Conference, San Diego, CA11/2010
State/Local Invited Seminars/Lectures, Quality Improvement Measures-Critical Exercise or Waste of Time?, Neonatal Group Meeting09/2010
Pediatric Grand Rounds, Quality Improvement Measures- Critical Exercise or Waste of time?, UMMC08/2010
Poster Presentation, Dexamethasone Induces Apoptosis And Neurodegeneration In Neonatal Rat Brain., Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, Vancouver, Canada05/2010
Poster Presentation, Corticosteroid Responses Following Hypoxic Preconditioning Provide Neuroprotection Against Subsequent Hypoxic-Ischemic Brain Injury in Newborn Rats, Southern Society of Pediatric Research Annual Conference, New Orleans, LA02/2010
Poster Presentation, Dexamethasone Decreases Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-II in the Neonatal Rat Brain, Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, Baltimore, Maryland05/2009
Scientific Presentations, Dexamethasone Decreases Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-II in the Neonatal Rat Brain, Southern Society of Pediatric Research Annual Conference, New Orleans, LA02/2009
Poster Presentation, Hypoxic Preconditioning Augments and Preserves the Increase in the mRNA Expression of VEGF Isoforms by Hypoxia-Ischemia in Newborn Rat Brain, Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, Honolulu, Hawaii05/2008
Platform Presentations, Neuroprotective Effects of Vascular Endothelial Growth Factor A (VEGF A) Following Hypoxic Ischemic Brain Injury in Neonatal Rats, Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, Toronto, Canada05/2007
Scientific Presentations, Hypoxia-Ischemia (HI) Increases Hypoxia-Inducible Factor 1α
(HIF-1α) in Developing Rat Brain, International Neuroscience Conference, New Orleans, LA		11/2003
Poster Presentation, Hypoxia-Ischemia (HI) Increases Hypoxia-Inducible Factor-1α (HIF-1α) and Vascular Growth Factor (VEGF) in Developing Rat Brain., Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, Seattle, Washington05/2003
Poster Presentation, Decreased Vascular Endothelial Growth Factor (VEGF), VEGF receptor (Flt-1) and Endothelial Marker, PECAM, in Premature Baboons with Chronic Lung Disease (CLD), American Thoracic Society International Conference, Toronto, Canada05/2000
Poster Presentation, Evidence for Disrupted Microvascular Development in Premature Human Infants Dying with Bronchopulmonary Dysplasia (BPD), American Thoracic Society International Conference, Toronto, Canada05/2000
Platform Presentations, Vascular Dysmorphic Changes in Premature Human Infants Dying with Bronchopulmonary Dysplasia., Easter Society of Pediatric Research Annual Conference, Atlantic City, NJ03/2000
Poster Presentation, Vascular Endothelial Growth Factor (VEGF), VEGF Receptor (FLK-1) and Hypoxia Inducible Factor - Like Factor (HLF) mRNA Abundance are Increased by Dexamethasone in Postnatal Mouse Lung, Pediatric Academic Societies - Society for Pediatric Research Annual Meeting, San Francisco, CA05/1999
Scientific Presentations, Dexamethasone Induces Vascular Endothelial Growth Factor (VEGF) and Hypoxia Inducible Factor - Like Factor (HLF) mRNA Abundance in Postnatal Mice., American Thoracic Society International Conference, San Diego, CA04/1999

Honors, Awards, and Recognition

UMMC GWIMS Trailbazer Award, UMMC Group on Woman in Medicine and Science2018
Intramural Funding- Hyperoxia, inflammation and cerebral white matter injury. Role: consultant, IRSP2014

Professional Membership and Service

Southern Society for Pediatric Research, Member
Society Of Pediatric Research, Member

Committee Service

Pedaitric Discovery Council, Member2016 - Present
Newborn Division P2 (Policy and Product Review) Committee, Member2013 - Present
Pediatric Discovery Council, Vice Chair2013 - 2016
Newborn Division Performance Improvement Committee, Member2013 - Present
Neonatal-Perinatal Fellowship Planning Committee, Member2012 - Present
Children's Heart Center Advisory Board, Member2012 - 2013
Pediatric Research Committee, Member2006 - 2013

Other Service

Research, Member, Internal Advisory Committee, Mississippi Center of Excellence in Perinatal Research, Member, Internal Advisory Committee, Mississippi Center of Excellence in Perinatal Research08/2017 - Present
Quality Improvement Project: Nosocomial Infection Prevention Task Force at the Newborn Center of Children’s of Mississippi, Organized the task force, Developed Vision and Goals, Member08/2014 - 05/2015
Quality Improvement Project: Golden Hour PI Team, Member05/2014 - Present
Quality Improvement Project: NICU Surfactant Administration PI Team, Lead Role2013 - 05/2014
Quality Improvement Project: NICU Temperature PI Team, Lead Role2013 - 05/2014
In-Charge Newborn Division Attending Scheduling2012 - Present
Quality Improvement Project: NICU Infection Prevention Team, Lead Role07/2009 - 07/2014

Teaching Experience

Medicine, Course Director, Pediatric Discovery Seminar - 2016
Medicine, Lecture, Course Director, Newborn Research Conference
Medicine, Small Group, Facilitator, Newborn Lab Research Monthly Meeting
Medicine, Small Group, Course Presenter, NICU Residents Morning Lectures

Fellows supervised

Neonata-Perinatal Medicine Fellowship, Research Advisor, 1 fellows supervised07/2019 - Present
Neonata-Perinatal Medicine Fellowship, Research Advisor, 1 fellows supervised12/2018 - Present
Neonatal-Perinatal Medicine, Research Advisor, 1 fellows supervised11/2017 - 06/2020
Neonatal-Perinatal Medicine, Research Advisor, 1 fellows supervised11/2017 - 06/2019
Neonatal-Perinatal Medicine, Academic Mentor, 1 fellows supervised01/2017 - Present
Neonatal_Perinatal Medicine, Research Advisor, 1 fellows supervised10/2015 - 06/2018
Neonatal-Perinatal Medicine, Research Advisor, 1 fellows supervised10/2014 - 07/2017
Neonatal-Perinatal Medicine, Attending Physician, 10 fellows supervised07/2014 - Present

Residency Training

Medicine-Pediatrics, Attending Physician2006 - Present
Pediatrics, Attending Physician2006 - Present
Pediatrics, Attending Physician2000 - 09/2003