Premature Infants Receiving Milking or Delayed Cord Clamping: Randomized Controlled Multicenter Non-Inferiority Trial: PREMOD2

About this Study

This study will compare the incidence of long-term neurodevelopmental outcomes at 24 months in premature infants receiving umbilical cord milking (UCM) to those receiving delayed cord clamping (DCC).

Sponsor Protocol ID:1612901
IRB Number:2019-0159
Actively Enrolling
Phase 1
November 25, 2019
Eligibility Criteria
8 years old
Both Male and Female

Exclusion Criteria

  • Congenital anomalies of newborn
  • Cardiac defects other than small VSD and PDA
  • Placenta abruption or previa with active bleeding, cutting through the placenta (Note: Partial abruptions are not excluded)
  • Cord prolapse
  • Hydrops
  • Bleeding Accreta
  • Monochorionic twins (Di/Mo or Mo/Mo)
  • Fetal risk or maternal risk for severe compromise at delivery identified by obstetrician or neonatologist 
  • Families unlikely to return for neurodevelopmental testing at 24 months

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Women's Health
Participating Locations
Batson Children’s Hospital
Wiser Hospital for Women and Infants
Contact Information
Contact Name: Sandra Tyler
Principal Investigator:Karam, Simon, M.D.
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