Premature Infants Receiving Milking or Delayed Cord Clamping: Randomized Controlled Multicenter Non-Inferiority Trial: PREMOD2

About this Study

This study will compare the incidence of long-term neurodevelopmental outcomes at 24 months in premature infants receiving umbilical cord milking (UCM) to those receiving delayed cord clamping (DCC).

Sponsor Protocol ID:1612901
IRB Number:2019-0159
Actively Enrolling
Interventional
Phase 1
November 25, 2019
Eligibility Criteria
8 years old
Both Male and Female
No
Yes
Yes

Exclusion Criteria

  • Congenital anomalies of newborn
  • Cardiac defects other than small VSD and PDA
  • Placenta abruption or previa with active bleeding, cutting through the placenta (Note: Partial abruptions are not excluded)
  • Cord prolapse
  • Hydrops
  • Bleeding Accreta
  • Monochorionic twins (Di/Mo or Mo/Mo)
  • Fetal risk or maternal risk for severe compromise at delivery identified by obstetrician or neonatologist 
  • Families unlikely to return for neurodevelopmental testing at 24 months

Categories Click category to view its trials.
Pediatrics
Women's Health
Participating Locations
Batson Children’s Hospital
Wiser Hospital for Women and Infants
Contact Information
Contact Name: Sandra Tyler
Email: sltyler@umc.edu
Principal Investigator:Karam, Simon, M.D.
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